CN1069600A - Control outside the dynamic chamber of laser energy output - Google Patents

Control outside the dynamic chamber of laser energy output Download PDF

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Publication number
CN1069600A
CN1069600A CN 91105538 CN91105538A CN1069600A CN 1069600 A CN1069600 A CN 1069600A CN 91105538 CN91105538 CN 91105538 CN 91105538 A CN91105538 A CN 91105538A CN 1069600 A CN1069600 A CN 1069600A
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China
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laser
energy
laser beam
pulse
value
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CN 91105538
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Chinese (zh)
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H·阿尔弗雷德·斯克拉
杰兹·欧基泽乌斯基
安德雷·M·里斯特万
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Phoenix Laser Systems Inc
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Phoenix Laser Systems Inc
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Priority to CN 91105538 priority Critical patent/CN1069600A/en
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Abstract

A kind of laser beam delivery system, the device that this system comprises a laser and is used for the pulse laser beam that is produced by laser is carried out the pulse-shaping parameter monitoring, it is characterized in that: an energy output transducer receives the laser beam energy of a part of laser beam delivery system, also has a laser beam intensity attenuator, be arranged on the anterior light path of transducer, be used for changing laser beam intensity, a control device, be used to receive signal from the laser energy transducer, and regulate laser beam strength retrogression device to some decay levels, with output that responds laser energy and the sensing that presets the deviation between the desired energy output valve.

Description

Control outside the dynamic chamber of laser energy output
The present invention relates to make laser energy output to remain on the interior a kind of control system of predetermined limits.
The invention provides a kind of simple, accurate and inexpensive system and method and be used to reduce the pulse of launching from pulse laser to the energy changing between the pulse, this system and method is especially to being used in the pulse laser of surgery system, and keeping its energy output is useful within quite approaching tolerance limit.
Laser is used in ophthalmology and the existing history more than 25 years of other surgical specialties, their successful Application so far, part are based on the surgeon to be had and can reduce or no longer need in some cases the ability that the mode of being in hospital is for a long time finished various processing with a kind of with laser surgical device; Part is based on laser aid and has the ability that generation depth groups loom can damage in seeing through the tissue of laser, than habitual non-laser treatment significantly less wound or damage arranged, and this disposal can be carried out in a kind of mode of expection.
The ophthalmologist is widely used in first expert in the surgery to laser.Traditionally, they avoid laser is mapped to too close responsive tissue place, because the light pulse of penetrating in the mistake in this place, perhaps excessive laser pulse might cause undesirable, even not repairable damage.A kind of method record order in February 6 nineteen ninety that is used to reduce the inaccuracy relevant with the misplace irradiation is submitted to, and the U.S. Patent application U.S.No.475 that is provided by assignee of the present invention is in 657.
The present invention discusses a kind of be restriction and the energy change relevant damage used method and system of undesirable pulse to pulse.
Cause its predictive of degree of tissue disruption to depend on the energy spoke degree and the distribution of this laser pulse to a great extent by a laser pulse.Owing to recognize and monitor and control the needs that pulsed laser energy changes, U.S.'s device and radiation health center (CDRH) and U.S. food and medication management center (FDA) but set up is used for the tolerance limit of the pulse change of Laser emission and repeat its transmission, and before each laser surgery disposes the standard and the criterion of testing laser method for transmitting.FDA requires to trigger a spot of test pulse, and takes a sample, and laser was assessed its performance before carrying out given surgical management.
The technology a kind of commonly used that is used to characterize the Laser emission characteristic is, total emission of a large amount of pulses is measured, if the average magnitude of energy and average deviation are positioned within the predetermined tolerance limit of predetermined value, can think that so this device satisfies the requirement of regulation.In other words, whether these method sighting target standards or average deviation surpass the deviation of maximum pulse to pulse.A used in practice typical standard is that pulse is changed to 20% to pulse energy.
In the photodisruption technology, to the damage of biological tissue or any other kind material normally with to have how many energy to be delivered to material from laser pulse proportional.
If energy value considerably beyond energy density and irradiance threshold value, may meet general proportional law less than 20% by the big or small difference of the caused infringement of 20% pulse change.Yet, if disposing task is to have surpassed on a certain value of damage threshold just to carry out.So, in addition by 20% or the difference of the following caused damage infringement of pulse change size may be about 300% to 400%, or higher.
Adopting the shortcoming of strict mean type standard is that average appearance value low concerning a series of laser pulses may be met, but still exists harmful big maximum pulse energy deviation.As above general introduction, big pulse to pulse energy rise and fall and may cause considerable and undesirable infringement in the tissue.Example as this damage is the loss of the endothelial cell that may be caused by the non-general big pulse that excimer laser produced when carrying out cornea refractive surgery.In this example, come off from the front surface of cornea and to spread the intracorneal pressure wave quite powerful endothelial cell dysfunction that causes that may become backward, cause blindness in some cases.
Other example is to carry out the rear part lens capsotomy with laser, and this oculist the lenticular film of laser alignment, and is used up and breaks it.Consider at annual nearly 1,200 ten thousand cataract patients of the U.S. and need carry out operation, and need carry out this rear part lens capsotomy about 20% among the patient, therefore in carrying out this operation, just need carry out completely and effectively control the energy of laser.Many producers' handbook suggestion surgeon or user are mapped to laser on the back crystalline peplos in the vitreum from behind, and progressively convergence is avoided any umbilication of lens that may cause when carrying out cataract operation as the rete of target with this from behind.If primary laser pulse afterwards consequently can not be to the lens capsule of back to leaning on very much, if perhaps the pulse energy of being launched is considerably beyond predetermined value, a very powerful pressure wave energy propagates into the vitreous-body-retina interface so, on retina, cause enough big draw, cause detachment of retina, this detachment of retina is a kind of complication that occurs usually after adopting laser to back lens capsule cutting operation.
According to the present invention, if recognize that first when making great efforts to control the emission of laser energy, the intrinsic parameter of laser is just changed, the variation of this parameter is introduced complicated transient changing through regular meeting.Departing from of this rated value usually is non-linear, and the way that exist to adopt the supposition iteration to reduce is set up a set of pulses specially to pulse output parameter repeatably.Therefore, important point of the present invention is that laser parameters is not modulated or controlled.Have only Laser emission,, just should and be controlled in the predetermined limit value this emission sampling in case exceed resonant cavity and enter the dispensing device of laser system.
A kind of habitual being used for monitors and the energy method for transmitting of controlling the used laser of surgical laser system is: (1) is placed on reflector back in the resonant cavity to energy-probe, (2) get the mean value that the penetration device is transferred to the predetermined pulse number of detector, (3), change the energy that is added on the laser medium in order to the variation that is taken place is compensated according to this mean value of asking for.For excimer laser, can adopt usually to change the change that the voltage make on the sparking electrode that laser medium is excited is obtained energy.The variation of this voltage shows the standard deviation of its energy that is enough to make excimer laser emission, under normal good operation situation, can be limited in 10% the average range of tolerable variance, and to this, can be referring to United States Patent (USP) U.S.P.No.4,611,270.The duration of such one section good surgical procedures condition, the pulse of perhaps control maximum to the variation of pulse is an an open question to excimer laser and many other laser systems.May in Laser emission, cause strong nonlinear change owing to change the voltage that is added to sparking electrode.Therefore, propose these methods are improved, tolerance is further reduced.
At surgery, need better control this requirement to the emission of laser is the requirement of controlling tissue damage from need subtly, to this point, especially more needs in ophthalmologic operation.To surgical laser system, require this system near the work of dielectric breakdown threshold value place, perhaps rely on the abducent shock wave of the result's who decomposes by laser induced plasma generation to produce uniform laser infringement.To this, the energy emission of controlling laser tightly be realize accurately, one of the key of surgical result that can indicate, safety.Photoemissive sampling should be continuous, is not limited to the several representative pulse before operation is disposed, and needs the dynamic interaction sampling to the whole surgery processing procedure.
Therefore, the present invention includes the apparatus and method of the energy of lasers output of dynamic monitoring and control surgical system, so that very narrow pulse to pulse error margin can obtain satisfied monitoring.In a preferred embodiment, this monitoring can obtain in the back of the beam splitter of laser beam emitting device by placing a detector, this detector is to the known fraction energy sampling from each laser pulse of system of laser surgery emission, and it is the energy that is come out by the excited target of laser own fully.Amplify with the signal of electronics method detector, and amplifying signal with compare by the software that standard produced of operator's pre-selected, to obtain the energy value that two quilts indicate, with the energy deviation that can receive, adjust output repeatedly until reaching desired value by variable attenuator of computer program operation.Preferably after each pulse, proofread and correct.In system to tolerance under unsatisfied situation, but to safety contact maker or other device move instruction, interrupt the transmission of laser beam.Thereby, the operating procedure that this system can carry out appointment again automatically continuously.
System of the present invention photicly will provide a kind of more uniform result when organizing body to break using superpower laser to cause to cause in biological tissue and other material.
The object of the present invention is to provide a kind of quite simple, but the control system of the laser energy emission value in more accurate, correct, safe and reliable the laser beam feed system that is used for, especially laser surgery field.Other purpose of invention, advantage and characteristic will be by the explanations of following preferred embodiment, and said clearly in conjunction with the accompanying drawings.
Fig. 1, the schematic diagram of a laser beam feed system example of energy monitoring of the present invention and control system is used in expression.
Fig. 2, the schematic diagram of the opticator of expression system shown in Figure 1.
Fig. 3, expression can be used for the schematic diagram of one type energy value detector of system of the present invention.
Fig. 4 to Fig. 8 is illustrated under the different situations, and laser energy is to the plot of laser beam time of being carried out; Fig. 4 to Fig. 6 represents that laser energy is useless to energy management system of the present invention; Fig. 5 to Fig. 7 represents that laser energy uses the obtained control result of control system of the present invention;
The termination that makes Laser emission owing to the energy that surpasses although Fig. 8 represents to add control.
In above-mentioned accompanying drawing, laser transmitting system 10 that is used for medical laser surgery system and surgical management of accompanying drawing 1 expression, at contextual accompanying drawing with in to this discussion of doing, described laser surgical device is relevant with ophthalmology; Yet the microsurgery of the precision of other form and accurate industrial micromachining also can utilize principle of the present invention and system to finish.
As shown in Figure 1, laser beam 12 is launched by lasing light emitter 14, laser 14 encouraged with all laser pulse shapings relevant with it after, laser beam 12 is advanced by the suitable optical element that comprises reflective mirror 16, light beam along as shown in Figure 1 upward to light path advance, until arriving a beam intensity attenuator 18.
Beam intensity attenuator 18 can be got any form, if it can with the quickish response time carry out optical attenuation just can, its response time is less than 1 millisecond of magnitude.In a preferred embodiment of the invention, optical attenuator 18 is made up of a kind of attenuator of polarization-type, and it acts on the linearly polarized laser bundle 12.Thus, attenuator 18 for example can comprise a polarizer 20(, an analyzer) and a half-wave postponement sheet 22.As shown in the figure, half-wave is postponed sheet and is placed on the turntable 24, by turntable half-wave is postponed and can be positioned to different rotational angles increases or reduce light with this degree of decay.Postponing sheet when rotating, be excited the plane of polarization of light beam to rotate in the speed of postponing sheet with two ones.Therefore, postpone sheet 22 rotations and just require plane of polarization to forward another parallel direction to for 45 °, rotated 90 °, just forwarded full attenuation to from total transmissivity from a parallel direction.As everyone knows, polarizer 20, its polarization direction with from the polarization direction of postponing the light beam that sheet 22 comes out when consistent, basically 100% ground sees through light intensity, equally, can decay light intensity, can drop to zero or approaching zero luminous intensity by the angle position of regulating half-wave postponement sheet 22.
The laser beam 12 that is come out by attenuator 18 can pass through various additional optical elements, as shown in Figure 1, these elements comprise, lens subassembly 26 is used to expand restraints into collimated light beam 12a, 32,34 pairs of collimated light beams 12 of reflective mirror 28,30 and beam splitter reflect and beam splitting, and reflective mirror 30 can be a tiltable beam steering control mirror.
Need to understand, the present invention only is one in the light beam transmitting system shown in Fig. 1 and gives an example.In following Fig. 3, the principle of the present invention of expression is the basic place of light beam transmitting system.
As shown in Figure 1, light 12a through expanding bundle arrives beam splitter 36, by a fraction of light beam 12b of beam splitter 36 transmissions, and remainder light is reflexed to a upper left objective lens unit 38 that is positioned at figure, focus optical beams to a target by object lens 38, for example on the eyes shown in Fig. 1 40.
Fig. 2 schematically illustrates the aft section of the described system of Fig. 1, has beam splitter 34 and 36, and objective lens unit 38 is in order to focused beam is positioned on the eyes 40, and as the accompanying drawing indication, beam splitter 34 and 36 can transmit the light that light returns from eyes to eyes or transmission.But these functions and device do not constitute a part of the present invention, only are as general expression.
The very low-energy light beam part 12b that sees through by beam splitter 36 represents the intensity of laser beam, and representative just sends to the energy level of the light beam of eyes.
In Fig. 1, light beam part 12b directive luminous intensity or energy value transducer 42.This transducer can adopt any intensity or energy sensitive device accurate, response fast, for example adopts by shown in Figure 3 the sort of.
As signal among Fig. 1 (or Fig. 3), transducer 42 sends a signal of telecommunication of representing with straight line 44 to controller, for example on microprocessor 46, controller or processor 46 adopt the suitable algorithm edit routines in order to receive and response receive can value variation, preferably carry out the processing of pulse, this be will be further described below to pulse change.Send into controller 46 from the tolerance limit size compiled program of a predetermined best or needed value preliminary election that output changes to energy, by controller to depart from that preset or required can value can the value variation respond, along diagram straight line 48 signal is sent to turntable 24 by motor driven with the form of formula, come controlling and driving 1/2 wavelength to postpone sheet 22.
Fig. 1 and 3 also represents other characteristic of the present invention, depart from preset value if detect certain laser pulse, this deviation value surpasses the tolerance limit of preliminary election, and the emission of laser stops so, (same) if pulsed laser energy is more much lower than preset value, the laser emission also stops.If detect the Laser emission outside tolerance limit, then microprocessor/or controller 46 just send a signal 49, this signal is sent to beam-switching device 50, simultaneously disconnected this Laser emission of retaining before the next pulse emission immediately.Derailing switch 50 for example can comprise a kind of Vincent Uniblitz switch.
Fig. 3 illustrates a kind of medium-sized integration light intensity detector, expression system of the present invention in the block diagram.Integrating sphere 52 has a perforate 54, allows fraction light by this hole, that is, the processing beam of representing with symbol 56 can enter perforate, and this light beam is represented with straight line 12b in Fig. 1 and 2.Because light beam 12b can be a kind of light beam that expands bundle, light beam focusing is entered in the ball so a positive lens can be set before integrating sphere.
According to well-known principle, the light that integrating sphere 52 focuses on and diffusion is taken a sample can be surveyed through integration sampling light intensity with energy monitor 42.Energy monitor 42 comprises: a photo-detector 58, silicon photo diode for example, in order to receive light by bandpass filter 60, bandpass filter 60 is narrow band pass filters, it can be specially by the wavelength of laser beam, and filtering any other external light, this ambient light may be from the used lighting source of system, or is introduced in the integrating sphere from the non-laser light source that any alternate manner enters system.Known, detector receives and to be similar to become with the approach axis of focused light 56 90 ° incident light, and only in this situation, light is just by second hole 62 in the integrating sphere.
As shown in Figure 3, the signal from photo-detector 58 can enter a sampling and holding device 64, amplifier 66 and buffer 68.Final then processing signals 44 is admitted to microprocessor controller 46.
Fig. 4,5,6,7 and 8 represent laser energy and time relation with graph mode, or laser energy is to the relation of each time Laser emission pulse.The laser energy of a series of continuous impulses that are not controlled that Fig. 4 and 6 expressions are sent by the Nd:YAG laser.Fig. 4 represents different moments with 6 figure that described, with the different trends of expression light energy.In all cases, the preset energy of Nd:YAG laser is 500 millijoules, and the system of the present invention of the graphical representation shown in Fig. 4 to 8 has been subjected to actual control, and used control algolithm is described below.
A kind of optimal algorithm of suitable system of the present invention is for the purpose of control, the moving average of laser energy to be calculated.Best, for SERVO CONTROL, after each Laser emission, calculate the moving average of laser energy once more.In a kind of enforcement of the best, use last 10 light emission, after each emission, calculate the laser energy moving average once more.Get poor between moving average and this system institute's energy requirement or the preset energy.After each emission, regulate the energy (available above-mentioned attenuator 18 is regulated) of light beam with the difference amount.By regulating with to compensating by the represented skew of last moving average calculation.
Be illustrated in Fig. 5 and 7 with the obtained result of system of the present invention, as seen, the output energy value remains in the envelope of closure of required 500 millijoules, rises and falls and is no more than 15% usually from these figure.
Fig. 8 illustrates the feature that stops of above-mentioned Laser emission.In Fig. 8, the output of laser is owing to pulse occurs and surpass the presetting limit value of each pulse and turn-offed by beam-switching device 50, before pulse appears at and turn-offs immediately.In this example, preset limit value and fix on 15% change place that departs from 500 millijoules institute energy requirement.
Preferred embodiment purpose recited above is to illustrate principle of the present invention, but does not limit its scope.Other embodiment and the change that above preferred embodiment is done will be conspicuous to the those skilled in the art of this area, and can not depart from the spirit and scope of the present invention as the regulation of following claim and carry out.

Claims (6)

1, a kind of laser beam delivery system, the device that this system comprises a laser and is used for the pulsed laser beam that is produced by laser is carried out the pulse shaping parameter monitoring, it is characterized in that, an energy output transducer receives the laser beam energy of a part from laser beam delivery system, this energy output transducer is placed in that all are relevant with laser on the laser pulse outbound course that parameter is shaped, the energy output transducer carries out continuous device for monitoring to laser energy during having laser operation, comprising being used to monitor the device of pulse to deviation between interpulse energy and the desirable energy output valve that presets
A laser beam intensity attenuator is arranged on the anterior light path of energy sensor, strength retrogression's utensil laser beam intensity that changes, thus change function by the laser beam energy output of attenuator,
A control device is used to receive the signal from the laser energy transducer, and regulates laser beam strength retrogression device to some decay levels, with the sensing of the deviation between the output of response laser energy and the desired energy output valve that presets.
2, the system as claimed in claim 1, it is characterized in that, control device also comprises the device that is used to turn-off Laser emission, and this device is used in energy sensor and is measured to through the laser beam of attenuator and controller and can value remain on predetermined tolerance limit shutoff Laser emission when interior.
3, system as claimed in claim 2 is characterized in that, the cutoff device of laser beam emission comprises, if any receive in the single laser arteries and veins its can be worth change surpass preset can value predetermined tolerance limit the time just disconnect photoemissive device.
4, described system as claimed in claim 1, it is characterized in that, laser beam is a linear polarization, the laser beam intensity attenuator comprises a linear polarization and a half-wave postponement sheet that is contained on the turntable, and the device that the rotation half-wave is postponed sheet is used for the amplitude of control response from the laser beam of the signal of described control device.
5, the system as claimed in claim 1, it is characterized in that, the algorithm that control device calculates according to the moving average of the selected laser pulse number of the train pulse that has just sent is operated, after each Laser emission, difference between the required value of getting moving average and presetting, variation by the rolling average value representation is compensated with attenuator according to described difference amount again, thereby realize the adjusting that beam energy is exported.
6, system as claimed in claim 5 is characterized in that, control device also be included in a single laser pulse that laser sensor detects its can be worth with preset can value the device that the disconnection laser energy is launched when surpassing predetermined tolerance value that departs from.
CN 91105538 1991-08-12 1991-08-12 Control outside the dynamic chamber of laser energy output Pending CN1069600A (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104741780A (en) * 2013-12-27 2015-07-01 Ap系统股份有限公司 Method and apparatus for compensating laser pulses
CN105167910A (en) * 2009-07-29 2015-12-23 爱尔康蓝斯克斯股份有限公司 Optical System With Movable Lens For Ophthalmic Surgical Laser
CN106238905A (en) * 2016-06-14 2016-12-21 昆山国显光电有限公司 A kind of laser energy automatic compensating method and equipment
CN106264855A (en) * 2016-10-13 2017-01-04 清华大学深圳研究生院 A kind of device for treating cornea tissue disease
CN107647913A (en) * 2017-10-31 2018-02-02 重庆京渝激光技术有限公司 The laser cure apparatus of display screen convenient for cleaning
CN111417487A (en) * 2018-01-24 2020-07-14 极光先进雷射株式会社 Laser processing method and laser processing system
CN112038267A (en) * 2020-09-21 2020-12-04 京东方科技集团股份有限公司 Laser energy adjusting device
CN112276345A (en) * 2020-10-10 2021-01-29 深圳市韵腾激光科技有限公司 Laser processing system and method for monitoring laser power change
CN114502119A (en) * 2019-07-19 2022-05-13 克拉诺瓦公司 Cutting device with optical coupler comprising polarization corrector

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105167910A (en) * 2009-07-29 2015-12-23 爱尔康蓝斯克斯股份有限公司 Optical System With Movable Lens For Ophthalmic Surgical Laser
CN104741780A (en) * 2013-12-27 2015-07-01 Ap系统股份有限公司 Method and apparatus for compensating laser pulses
CN104741780B (en) * 2013-12-27 2017-09-08 Ap系统股份有限公司 Method and apparatus for calibration of laser pulse
CN106238905A (en) * 2016-06-14 2016-12-21 昆山国显光电有限公司 A kind of laser energy automatic compensating method and equipment
CN106238905B (en) * 2016-06-14 2019-06-21 昆山国显光电有限公司 A kind of laser energy automatic compensating method and equipment
CN106264855B (en) * 2016-10-13 2018-11-06 清华大学深圳研究生院 A kind of device for treating cornea tissue disease
CN106264855A (en) * 2016-10-13 2017-01-04 清华大学深圳研究生院 A kind of device for treating cornea tissue disease
CN107647913A (en) * 2017-10-31 2018-02-02 重庆京渝激光技术有限公司 The laser cure apparatus of display screen convenient for cleaning
CN107647913B (en) * 2017-10-31 2023-12-08 重庆京渝激光技术有限公司 Laser therapeutic machine convenient for cleaning display screen
CN111417487A (en) * 2018-01-24 2020-07-14 极光先进雷射株式会社 Laser processing method and laser processing system
CN114502119A (en) * 2019-07-19 2022-05-13 克拉诺瓦公司 Cutting device with optical coupler comprising polarization corrector
CN112038267A (en) * 2020-09-21 2020-12-04 京东方科技集团股份有限公司 Laser energy adjusting device
CN112038267B (en) * 2020-09-21 2024-02-20 京东方科技集团股份有限公司 Laser energy adjusting device
CN112276345A (en) * 2020-10-10 2021-01-29 深圳市韵腾激光科技有限公司 Laser processing system and method for monitoring laser power change
CN112276345B (en) * 2020-10-10 2021-06-01 深圳市韵腾激光科技有限公司 Laser processing system and method for monitoring laser power change

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