CN106947668A - A kind of Chinese medicinal liquor with effect for reducing blood fat - Google Patents
A kind of Chinese medicinal liquor with effect for reducing blood fat Download PDFInfo
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Abstract
The present invention relates to the Chinese medicinal liquor with effect for reducing blood fat, the problem of effectively can solving high fat of blood, its technical scheme solved is that the Chinese medicinal liquor is made up of the raw material of following ratio of weight and number：40 50 parts of glutinous rice, 60 70 parts of Chinese medicine, medicine bent 25 30 parts and 15 parts of distiller's yeast；Described Chinese medicine is made up of the material medicine of following ratio of weight and number：12 parts of 40 50 parts of fresh rehmannia root, 38 parts of fresh oriental wormwood, 36 parts of hawthorn, 35 parts of the Radix Astragali, 35 parts of fructus cannabis, 35 parts of almond and Radix Glycyrrhizae；Described distiller's yeast is yellow wine yeast, one kind of red yeast rice or two kinds of mixture；Gained finished product uniform color of the invention is into yellow rice wine sample, 12 20 degree of alcoholic strength, and mouthfeel micro-sweet, acid with medicine fragrance, take safety, effect for reducing blood fat is obvious, is the innovation on wine product.
Description
Technical field
The present invention relates to herb fermenting health product technology field, particularly a kind of Chinese medicinal liquor with effect for reducing blood fat.
Background technology
China is in the high speed development stage, and social competition is extremely fierce, and most people is just faced with society from being born
Huge pressure and quick rhythm of life, cause its body function constantly to decline, and the continuous improvement of living standard, on ordinary days should
Reward is more, changes the dietary structure of people, people constantly feed high heat, higher fatty acid, high sugar, high salt, the food of high cholesterol
Product, and lack motion, cause to occur fat, and then cause the people of hyperlipemia year by year into ascendant trend at full speed, especially in,
Young Patients patient populations rapidly increase, many with light, moderate fatty liver and high fat of blood.
Numerous studies data shows, hyperlipemia is that cerebral apoplexy, coronary heart disease, myocardial infarction, cardiac sudden death are independent and important
Hazards, human body obesity can be caused, organism endocrine is disorderly, accelerate human senility, reduction body immunity.
The medicinal history of Chinese medicinal liquor is very long, in ancient times medical book, such as《General Records of Holy Universal Relief》、《Peaceful holy benevolent prescriptions》、《A thousand pieces of gold will
Side》Deng in ancient book it is on the books, can make us filling in effect it is happy can eat, benefiting energy, improving eyesight of making light of one's life by commiting suicide etc..There are lot of documents report in modern times
On the research of Chinese medicinal liquor effect for reducing blood fat, but more with soaking in Chinese liquor Chinese medicine, then seepage is obtained, and lipid-lowering effect is poor, in
Medicine is unable to good absorption, does not also reach good lipid-lowering effect while wasting Chinese medicine, therefore, the improvement of Chinese medicinal liquor and wound
The problem of being newly current urgent need to resolve.
The content of the invention
For above-mentioned situation, to solve the defect of prior art, the purpose of the present invention, which is just to provide one kind, has reducing blood lipid
The Chinese medicinal liquor of effect, the problem of effectively can solving high fat of blood.
The technical scheme that the present invention is solved is that the Chinese medicinal liquor is made up of the raw material of following ratio of weight and number：Glutinous rice 40-50
1-5 parts of part, 60-70 parts of Chinese medicine, 25-30 parts of medicine song and distiller's yeast；Described Chinese medicine is by the material medicine of following ratio of weight and number
It is made：40-50 parts of fresh rehmannia root, fresh oriental wormwood 3-8 parts, 3-6 parts of hawthorn, 3-5 parts of the Radix Astragali, 3-5 parts of fructus cannabis, 3-5 parts of almond and sweet
It is careless 1-2 parts；Described distiller's yeast is yellow wine yeast, one kind of red yeast rice or two kinds of mixture.
The preparation method of the Chinese medicinal liquor, comprises the following steps：
1) above-mentioned Chinese medicine is brewageed into the constitutive material with effect for reducing blood fat Chinese medicinal liquor just handle：
(a) fresh rehmannia root, net system cuts sheet 3mm, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter obtains fresh
Glutinous rehmannia juice and the dregs of a decoction, it is stand-by；
(b) fresh oriental wormwood, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter obtains fresh Oriental wormwood juice, stand-by；
(c) almond, net system, removal is gone mouldy product, put boiled in boiling water to skin it is micro- swollen when, pull out, slightly soaked with cold water, take out, go
Pi Jian, 80 DEG C of dryings obtain benevolence, take benevolence to put in the machine for stir-frying Chinese medicine of preheating to constant weight in drying box, fry slightly yellow to showing with slow fire,
Slightly focal spot, has fragrance, taking-up to be crushed after cooling, crosses No. 1 sieve, and making drugs into frostlike powder of extracting oil obtains almond meal, stand-by；
(d) fructus cannabis, net system is heated with slow fire, is fried to there is fragrance, in slightly yellow, is taken out, crushed after cooling, cross No. 1
Sieve, making drugs into frostlike powder of extracting oil obtains fructus cannabis frost, stand-by；
(e) Radix Astragali, hawthorn and Radix Glycyrrhizae drying removes moisture at 80 DEG C respectively, crushed No. 1 sieve, and obtained the Radix Astragali, hawthorn, sweet
Grass meal end；
2) untill glutinous rice to be dipped to easy two valve of hand stone roller in clear water, the glutinous rice soaked is rinsed well with running water, dripped
Solid carbon dioxide is rearmounted to be lined with the steaming in container of gauze, closed to steam to glutinous rice without the raw heart, loose not paste, thoroughly without rotten, uniformity
Untill, steamed glutinous rice is eluted with cold water, a little cold water is drenched while stirring, rice temperature is quickly down to 28-33 DEG C,
Obtain glutinous rice；
3) prepared by medicine song：By step 1) the fresh rehmannia root dregs of a decoction that prepare mix with wheat bran, flour, the fresh rehmannia root dregs of a decoction and wheat bran,
Flour weight ratio is 8：1：1, add water and be kneaded into agglomerate, be then charged into bent mold forming, curved billet is poured out, and hangs 1-3h, culture of entering the room,
24-36h is cultivated in culturing room, is during which turned over 1 time every 4-6h, temperature control is at 30-37 DEG C, when temperature gradually decreases down 25-
At 27 DEG C, that is, finished medicines song is obtained, it is standby；
4) using step 2) glutinous rice (be used as wine brewing matrix) for preparing, step 1) in the fresh rehmannia root juices of Processing methods, fresh mattress
Old juice, hawthorn fruit, Milkvetch Root, fructus cannabis frost, almond meal and Radix Glycyrrhizae powder, step 3) the medicine Qu Junyu distiller's yeasts that prepare
It is mixed and stirred for uniform；
5) by above-mentioned steps 4) obtained by mixture be transferred in sterilized round, compacting mixture, floating table
Face, middle nest, sealing is placed in incubator and fermented 15-20 days, and solid fermentation-saccharifying is carried out first, and temperature is maintained at
31-35 DEG C, turn over 1-4 times daily, fermentation is to when saccharification juice is at the high 3/5-4/5 in mixture surface, and after 5-7 days, add water 40-
50 parts, secondary fermentation is carried out, turns over 1-3 times within 8-12 days, was turned over every 1 day 1 time daily within 13-20 days；
6) by above-mentioned steps 5) obtained by fermenting mixture carry out expression separation and obtain raw wine, alcoholic strength is measured in 12-20 degree；
7) by above-mentioned steps 6) obtained by raw wine decocted, after intense fire is fried boiling, then to be cooked by slow fire 5min, stand 24h,
Filtering, obtained filtrate is closed, carries out ageing 30 days, gets product Chinese medicinal liquor.
Gained finished product uniform color of the invention is into yellow rice wine sample, alcoholic strength 12-20 degree, mouthfeel micro-sweet, acid, with medicine fragrance,
Safety is taken, effect for reducing blood fat is the innovation on wine product substantially.
Embodiment
The embodiment to the present invention is described in further detail with reference to embodiments.
Embodiment 1
The present invention in the specific implementation, can also be made up of the raw material of following ratio of weight and number：40 parts of glutinous rice, 64 parts of Chinese medicine,
Medicine bent 26 parts and 3 parts of distiller's yeast；Described Chinese medicine is made up of the material medicine of following ratio of weight and number：40 parts of fresh rehmannia root, fresh mattress
1 part of old 5 parts, 5 parts of hawthorn, 5 parts of the Radix Astragali, 5 parts of fructus cannabis, 3 parts of almond and Radix Glycyrrhizae.
Specific preparation method, comprises the following steps:
1) above-mentioned Chinese medicine is brewageed into the constitutive material with effect for reducing blood fat Chinese medicinal liquor just handle：
(a) fresh rehmannia root 40kg, net system cuts sheet 3mm, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter
Fresh rehmannia root juice and the dregs of a decoction are obtained, it is stand-by；
(b) fresh oriental wormwood 5kg, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter obtains fresh Oriental wormwood juice, stand-by；
(c) almond 3kg, net system, removal is gone mouldy product, put boiled in boiling water to skin it is micro- swollen when, pull out, slightly soaked with cold water, taken out,
Peeling point, 80 DEG C of dryings obtain benevolence, take benevolence to put in the machine for stir-frying Chinese medicine of preheating to constant weight in drying box, are fried with slow fire to showing micro- Huang
Color, slightly focal spot, have fragrance, taking-up to be crushed after cooling, cross No. 1 sieve, and making drugs into frostlike powder of extracting oil obtains almond meal, stand-by；
(d) fructus cannabis 5kg, net system is heated with slow fire, is fried to there is fragrance, in slightly yellow, is taken out, crushed after cooling, cross 1
Number sieve, extract oil making drugs into frostlike powder, obtain fructus cannabis frost, it is stand-by；
(e) drying removes moisture at 80 DEG C respectively by Radix Astragali 5kg, hawthorn 5kg and Radix Glycyrrhizae 1kg, crushed No. 1 sieve, and obtained yellow
Stilbene, hawthorn, Radix Glycyrrhizae powder；
2) untill glutinous rice 40kg being dipped into easy two valve of hand stone roller in clear water, the glutinous rice soaked is rinsed dry with running water
Only, drain the water it is rearmounted be lined with the steaming in container of gauze, it is closed to steam to glutinous rice without the raw heart, it is loose not paste, thoroughly without rotten, uniformly
Untill consistent.Steamed glutinous rice is eluted with cold water, a little cold water is drenched while stirring, rice temperature is quickly down to 31
℃；
3) prepared by medicine song：By step 1) prepare the fresh rehmannia root dregs of a decoction mixed with wheat bran, flour, three's weight ratio be 8：1：1,
Add water and be kneaded into agglomerate, be then charged into bent mold forming, curved billet is poured out, and hangs 2h, 28h, phase are cultivated in culture of entering the room in culturing room
Between turned over 1 time every 4h, temperature control is at 35 DEG C, when temperature gradually decreases down 25 DEG C, that is, it is bent to obtain finished medicines, standby；
4) by step 2) glutinous rice for preparing, add step 1) in obtained fresh rehmannia root juice, fresh Oriental wormwood juice, hawthorn fruit,
Milkvetch Root, fructus cannabis frost, almond meal and Radix Glycyrrhizae powder, step 3) medicine for preparing is bent, and distiller's yeast 3kg, mix
Uniformly；
5) by above-mentioned steps 4) obtained by mixture be transferred in sterilized round, compacting mixture, floating table
Face, middle nest, sealing is placed and solid fermentation is carried out in incubator, is fermented 16 days, is turned over daily within first 5 days 3 times, 6-12 days daily
Turn over 2 times, the 7th day 40kg that adds water was turned over 1 time, fermentation temperature is maintained at 32 DEG C for 13-16 days every 1 day；
6) by above-mentioned steps 5) obtained by fermenting mixture carry out expression separation and obtain raw wine, alcoholic strength is measured at 13 degree；
7) by above-mentioned steps 6) obtained by raw wine decocted, after intense fire is fried boiling, then to be cooked by slow fire 5min, stand 24h,
Filtering, obtained filtrate is closed, carries out ageing 30 days, gets product Chinese medicinal liquor.
Embodiment 2
The present invention in the specific implementation, can also be made up of the raw material of following ratio of weight and number：45 parts of glutinous rice, 68 parts of Chinese medicine,
Medicine is bent 27 parts, 4 parts of distiller's yeast；Described Chinese medicine is made up of the material medicine of following ratio of weight and number：45 parts of fresh rehmannia root, fresh oriental wormwood
1 part of 6 parts, 4 parts of hawthorn, 4 parts of the Radix Astragali, 4 parts of fructus cannabis, 4 parts of almond and Radix Glycyrrhizae.
Specific preparation method, comprises the following steps:
1) above-mentioned Chinese medicine is brewageed into the constitutive material with effect for reducing blood fat Chinese medicinal liquor just handle：
(a) fresh rehmannia root 45kg, net system cuts sheet 3mm, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter
Fresh rehmannia root juice and the fresh rehmannia root dregs of a decoction are obtained, it is stand-by；
(b) fresh oriental wormwood 6kg, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter obtains fresh Oriental wormwood juice, stand-by；
(c) almond 4kg, net system, removal is gone mouldy product, put boiled in boiling water to skin it is micro- swollen when, pull out, slightly soaked with cold water, taken out,
Peeling point, 80 DEG C of dryings obtain benevolence, take benevolence to put in the machine for stir-frying Chinese medicine of preheating to constant weight in drying box, are fried with slow fire to showing micro- Huang
Color, slightly focal spot, have fragrance, taking-up to be crushed after cooling, cross No. 1 sieve, and making drugs into frostlike powder of extracting oil obtains almond meal, stand-by；
(d) fructus cannabis 4kg, net system is heated with slow fire, is fried to there is fragrance, in slightly yellow, is taken out, crushed after cooling, cross 1
Number sieve, extract oil making drugs into frostlike powder, obtain fructus cannabis frost, it is stand-by；
(e) drying removes moisture at 80 DEG C respectively by Radix Astragali 4kg, hawthorn 4kg and Radix Glycyrrhizae 1kg, crushed No. 1 sieve, and obtained yellow
Stilbene, hawthorn, Radix Glycyrrhizae powder；
2) untill glutinous rice 45kg being dipped into easy two valve of hand stone roller in clear water, the glutinous rice soaked is rinsed dry with running water
Only, drain the water it is rearmounted be lined with the steaming in container of gauze, it is closed to steam to glutinous rice without the raw heart, it is loose not paste, thoroughly without rotten, uniformly
Untill consistent, steamed glutinous rice is eluted with cold water, a little cold water is drenched while stirring, rice temperature is quickly down to 31
℃；
3) prepared by medicine song：By step 1) prepare the fresh rehmannia root dregs of a decoction mixed with wheat bran, flour, three's weight ratio be 8：1：1,
Add water and be kneaded into agglomerate, be then charged into bent mold forming, curved billet is poured out, and hangs 3h, 28h, phase are cultivated in culture of entering the room in culturing room
Between turned over 1 time every 4h, temperature control is at 37 DEG C, when temperature gradually decreases down 26 DEG C, that is, it is bent to obtain finished medicines, standby；
4) by step 2) glutinous rice for preparing, add step 1) in obtained fresh rehmannia root juice, fresh Oriental wormwood juice, hawthorn fruit,
Milkvetch Root, fructus cannabis frost, almond meal and Radix Glycyrrhizae powder, step 3) medicine for preparing is bent, and distiller's yeast 4kg, mix
Uniformly；
5) by above-mentioned steps 4) obtained by mixture be transferred in sterilized round, compacting mixture, floating table
Face, middle nest, sealing is placed and solid fermentation is carried out in incubator, is fermented 18 days, is turned over daily within first 7 days 4 times, 8-12 days daily
Turn over 2 times, the 7th day 45kg that adds water was turned over 1 time, fermentation temperature is maintained at 34 DEG C for 13-18 days every 1 day；
6) by above-mentioned steps 5) obtained by fermenting mixture carry out expression separation and obtain raw wine, alcoholic strength is measured at 13 degree；
7) by above-mentioned steps 6) obtained by raw wine decocted, after intense fire is fried boiling, then to be cooked by slow fire 5min, stand 24h,
Filtering, obtained filtrate is closed, carries out ageing 30 days, gets product Chinese medicinal liquor.
Embodiment 3
The present invention in the specific implementation, can also be made up of the raw material of following ratio of weight and number：50 parts of glutinous rice, 70 parts of Chinese medicine,
Medicine is bent 28 parts, 5 parts of distiller's yeast；Described Chinese medicine is made up of the material medicine of following ratio of weight and number：50 parts of fresh rehmannia root, fresh oriental wormwood
1 part of 5 parts, 4 parts of hawthorn, 3 parts of the Radix Astragali, 4 parts of fructus cannabis, 3 parts of almond and Radix Glycyrrhizae.
Specific preparation method, comprises the following steps:
1) above-mentioned Chinese medicine is brewageed into the constitutive material with effect for reducing blood fat Chinese medicinal liquor just handle：
(a) fresh rehmannia root 50kg, net system cuts sheet 3mm, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter
Fresh rehmannia root juice and the dregs of a decoction are obtained, it is stand-by；
(b) fresh oriental wormwood 5kg, puts and crushed in juice extractor (80 revs/min) to pulpous state, squeeze and filter obtains fresh Oriental wormwood juice, stand-by；
(c) almond 3kg, net system, removal is gone mouldy product, put boiled in boiling water to skin it is micro- swollen when, pull out, slightly soaked with cold water, taken out,
Peeling point, 80 DEG C of dryings obtain benevolence, take benevolence to put in the machine for stir-frying Chinese medicine of preheating to constant weight in drying box, are fried with slow fire to showing micro- Huang
Color, slightly focal spot, have fragrance, taking-up to be crushed after cooling, cross No. 1 sieve, and making drugs into frostlike powder of extracting oil obtains almond meal, stand-by；
(d) fructus cannabis 4kg, net system is heated with slow fire, is fried to there is fragrance, in slightly yellow, is taken out, crushed after cooling, cross 1
Number sieve, extract oil making drugs into frostlike powder, obtain fructus cannabis frost, it is stand-by；
(e) drying removes moisture at 80 DEG C respectively by Radix Astragali 3kg, hawthorn 4kg and Radix Glycyrrhizae 1kg, crushed No. 1 sieve, and obtained yellow
Stilbene, hawthorn, Radix Glycyrrhizae powder；
2) untill glutinous rice 50kg being dipped into easy two valve of hand stone roller in clear water, the glutinous rice soaked is rinsed dry with running water
Only, drain the water it is rearmounted be lined with the steaming in container of gauze, it is closed to steam to glutinous rice without the raw heart, it is loose not paste, thoroughly without rotten, uniformly
Untill consistent, steamed glutinous rice is eluted with cold water, a little cold water is drenched while stirring, rice temperature is quickly down to 31
℃；
3) prepared by medicine song：By step 1) prepare the fresh rehmannia root dregs of a decoction mixed with wheat bran, flour, three's weight ratio be 8：1：1,
Add water and be kneaded into agglomerate, be then charged into bent mold forming, curved billet is poured out, and hangs 3h, 32h, phase are cultivated in culture of entering the room in culturing room
Between turned over 1 time every 5h, temperature control is at 37 DEG C, when temperature gradually decreases down 27 DEG C, that is, it is bent to obtain finished medicines, standby；
4) by step 2) glutinous rice for preparing, add step 1) in obtained fresh rehmannia root juice, fresh Oriental wormwood juice, hawthorn fruit,
Milkvetch Root, fructus cannabis frost, almond meal and Radix Glycyrrhizae powder, step 3) medicine for preparing is bent, and distiller's yeast 5kg, mix
Uniformly；
5) by above-mentioned steps 4) obtained by mixture be transferred in sterilized round, compacting mixture, floating table
Face, middle nest, sealing is placed and solid fermentation is carried out in incubator, is fermented 20 days, is turned over daily within first 7 days 4 times, 8-12 days daily
Turn over 2 times, the 7th day 50kg that adds water was turned over 1 time, fermentation temperature is maintained at 34 DEG C for 13-20 days every 1 day；
6) by above-mentioned steps 5) obtained by fermenting mixture carry out expression separation and obtain raw wine, alcoholic strength is measured at 14 degree；
7) by above-mentioned steps 6) obtained by raw wine decocted, after intense fire is fried boiling, then to be cooked by slow fire 5min, stand 24h,
Filtering, obtained filtrate is closed, carries out ageing 30 days, gets product Chinese medicinal liquor.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and
Within principle, any modifications, equivalent substitutions and improvements that the medicinal liquor fermented using fresh rehmannia root by main ingredient is made etc. should be included in
Within protection scope of the present invention.
Fresh rehmannia root has clearing heat and cooling blood in prescription；Effect of fluid dryness, main acute fever；Unconsciousness due to high fever；Macula；Tianjin wound is tired
Yearningly；The haematemesis of blood-heat bleeding；Uterine bleeding；Have blood in stool；Aphthae；Abscess of throat；Labor heat cough；Injuries from falls as well；It is too fat to move.Fresh oriental wormwood is clear
Damp and hot, removing jaundice subcutaneous ulcer cures mainly jaundice, scanty drak urine, wet sore.Hawthorn appetite-stimulating indigestion-relieving, the stagnant disperse accumulations of change, promoting blood circulation to remove blood stasis, resolving sputum promoting the circulation of qi, are used
In carnivorous stagnant product, a lump in the abdomen causing distension and pain, abdominal distension feeling of fullness, stasis blocking stomachache, phlegm and retained fluid, diarrhea, discharging fresh blood stool etc..The Radix Astragali has invigorating qi for strengthening superficies,
Diuretic and maintain drug, apocenosis, effect of expelling pus and promoting granulation, for treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time is had blood in stool and collapsed
Leakage, exterior deficiency spontaneous perspiration, ulcer is difficult to burst, burst for a long time and does not holds back, blood deficiency chlorosis, Heat Diabetes.Fructus cannabis relaxes bowel, and cures mainly blood
Empty body fluid deficiency, dry constipation of intestines.Almond has sending down abnormally ascending relieving cough and asthma, the effect relaxed bowel, cures mainly cough and asthma fullness sensation in chest abundant expectoration, intestinal dryness is just
It is secret.Radix Glycyrrhizae has invigorating middle warmer and replenishing QI, and relieving spasm to stop pain moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription, for weakness of the spleen and the stomach, lassitude hypodynamia,
Palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle sore tumefacting virus alleviate drug toxicity, strong.
Chinese medicinal liquor prepared by the present invention, feature is to instruct, with reference to Traditional Chinese Medicine clinical application according to traditional Chinese medical theory
Feature, using monarch, minister, helps, makes drug matching as foundation, and medicine is with clearing heat and cooling blood, enriching yin, promoting blood circulation to remove blood stasis, tonifying Qi, and relax bowel medicine
Based on, autotelic processing and processing are carried out to Chinese medicine used, using Modern microbiological microflora fermentation technique and technology, tool is prepared
Have in the Chinese medicinal liquor of effect for reducing blood fat, fermentation process, original composition contained by the Chinese medicine such as fresh rehmannia root is decomposed, and generates substantial amounts of
Secondary metabolite, produces and strengthens its effect for reducing blood fat.Full presciption medicine is simple and work(writes, real through patient clinical application test and pharmacology
Checking is bright to have obvious blood fat reducing function, has the effect for improving immune function of human body concurrently, and the preparation method of Chinese medicinal liquor includes：In
Prepared by medicine pretreatment, medicine song, raw material is mixed, ferment, decoct the process such as wine and ageing, it is ensured that lipid-lowering effect, and is tried through science
Test and practical application, achieve very satisfied Advantageous Effects, relevant testing data is as follows:
First, Chinese medicinal liquor prepared by the present invention has to hyperlipemia rat weight and liver index significantly reduces effect, and nothing
Toxic and side effect：
Healthy male SD rat, adaptability is raised 1 week, claims weight, and extracting 10 using random digits table is only used as sky
White control group, remaining is with lard 10%+ cholesterol 2%+ propylthiouracil 0.2%+ yolk powder 5%+ basal feeds 82.8%
Formula composition high lipid food feed, replicate hyperlipemia card rat model, be divided into the basic, normal, high dosage of model control group, Chinese medicinal liquor
Group model.Compared with blank control group, the weight of model control group, liver index rise have significant difference (P<
0.05), Chinese medicinal liquor each group compared with blank control group without significant difference；Compared with model control group, Chinese medicinal liquor each group
Weight, liver index have the trend of reduction, there is significant difference (P<0.05).Show that Chinese medicinal liquor has the work of reduction hyperlipemia
With being had no significant effect to the weight of hyperlipidemia rat, show that Chinese medicinal liquor has no toxic side effect.
The each group rat weight of table 1 compared with liver index (N=50)
Note：Compared with blank control group, * P<0.05, * * P<0.01；Compared with model control group,△P<0.05,△△P<
0.01。
2nd, Chinese medicinal liquor prepared by the present invention has adjustment effect to hyperlipemia rat blood lipid level：
Compared with Normal group, rat model serum TC (T-CHOL), TG (triglycerides), LDL-C (low density lipoproteins
Albumen), AST (glutamic-oxalacetic transaminease), ALT (glutamic-pyruvic transaminase) significantly raise, difference is statistically significant (P ＜ 0.05), and
Also there is elevated trend to HDL-C (HDL), point out to replicate the success of rat high blood lipid model.With model control group ratio
, middle dose group TC, TG, LDL-C, AST, ALT level high compared with, Chinese medicinal liquor is significantly reduced (P ＜ 0.05), point out Chinese medicinal liquor it is high, in
Dosage has certain effect for reducing fat to hyperlipemia rat, simultaneously effective reduces hepatic lesion caused by hyperlipemia.
Table 2 to hyperlipemia rat blood lipid level influence (N=50)
Note：Compared with blank control group, * P<0.05, * * P<0.01；Compared with model control group,△P<0.05,△△P<
0.01。
3rd, the Chinese medicinal liquor that prepared by the present invention is notable to high fat of blood subject's effect for reducing blood fat
Taken a blood sample 2 times in subject 6 months, 2 T-CHOLs >=5.2mmol/L or triglycerides >=1.65mmol/L,
Without obvious brain, the heart, liver, lung, kidney, Hematological Diseases, no Long-term taking medicine history and voluntarily tested, it is ensured that coordinate, be defined as simple high blood
Fat patient's study subject.At 18~65 years old age, be divided into two groups, Chinese medicinal liquor group 20, male/female is 10/10, the age for (43.52 ±
7.87) year；Control group 20, male/female is 10/10, the age be (45.30 ± 8.38) year；Two groups of sexes, ages are relatively without aobvious
Write difference (P>0.05).Compare no significant difference between TC, TG and HDL-C group of 2 measure of Chinese medicinal liquor group and control group and in group
(P>0.05), test-meal experiment by double-blind study carry out, using itself between group two kinds of control designs.Control group and Chinese medicinal liquor group are tested
It is 10 milliliters that person drinks placebo (white wine and brown sugar, which reconcile, to be formed) and Chinese medicine capacity for liquor every time respectively, early, middle and late respectively to take 1 time, even
Continuous to take 42d, Chinese medicinal liquor group is after test-meal Chinese medicinal liquor, and cholesterol in serum (TC) content reduces the reduction of 11.86%, TG contents
16.07%, HDL-C content raise 0.16mmol/L, and serum TC, TG, HDL-C content are without notable change before and after control group test-meal
Change, illustrate that Chinese medicinal liquor has effect for reducing blood fat, and effect is significantly, the results are shown in Table 3, takes the subject of Chinese medicinal liquor of the present invention, its
Blood fat has a different degrees of reduction, efficient up to 100%, effect it is good, do not expected.
The test-meal of table 3 experiment before serum TC, TG, HDL-C level (N=40)
Note：Compared with before test-meal, * P<0.05；Compared with control group,△P<0.05。
Compared with the existing medicinal liquor technology containing glutinous rehmannia, the present invention has advantages below：
1st, in the Chinese medicinal liquor of the present invention with effect for reducing blood fat Chinese medicine each component strictly by traditional Chinese medical science monarch, minister, help, make
It is required that carrying out compatibility, rationally, each traditional Chinese medicinal components have played the effect of Synergistic to scientific formula；
2nd, can with the microorganism species of medicine song culture in the Chinese medicine method for preparing medicated wine of the present invention with effect for reducing blood fat
Sufficiently the beneficial composition of the paired human body of Chinese herbal medicine decomposition and inversion, to compare the Chinese medicinal liquor obtained with immersion, the Chinese medicine such as glutinous rehmannia
In active ingredient more can incorporate in wine, while producing this substantial amounts of life metabolite, clinical test results show reducing blood lipid
Significantly, wide market is worth promoting action effect；
3rd, the flavour of a drug of Chinese medicinal liquor of the present invention are simplified, and medicine is non-toxic Chinese medicine in addition to almond, and almond by frying and
Making drugs into frostlike powder is greatly reduced without additives such as any pigment, spices in its toxic and side effect, preparation process, the Chinese medicine prepared
Wine, taste micro-sweet, acid, aroma and medicine are aromatic strongly fragrant；
4th, Chinese medicinal liquor preparation technology of the present invention is simple, and normal temperature and pressure is brewed, not high to equipment and site requirements, with investment
Few advantage, meets industrialization production requirements, with good economic and social benefit.
Claims (5)
1. a kind of Chinese medicinal liquor with effect for reducing blood fat, it is characterised in that the Chinese medicinal liquor is by the raw material of following ratio of weight and number
It is made：1-5 parts of 40-50 parts of glutinous rice, 60-70 parts of Chinese medicine, 25-30 parts of medicine song and distiller's yeast；Described Chinese medicine is by following parts by weight
The material medicine of number ratio is made：40-50 parts of fresh rehmannia root, fresh oriental wormwood 3-8 parts, 3-6 parts of hawthorn, 3-5 parts of the Radix Astragali, 3-5 parts of fructus cannabis,
1-2 parts of 3-5 parts of almond and Radix Glycyrrhizae；Described distiller's yeast is yellow wine yeast, one kind of red yeast rice or two kinds of mixture.
2. the Chinese medicinal liquor according to claim 1 with effect for reducing blood fat, it is characterised in that by following ratio of weight and number
Raw material is made：40 parts of glutinous rice, 64 parts of Chinese medicine, medicine bent 26 parts and 3 parts of distiller's yeast；Described Chinese medicine is by the original of following ratio of weight and number
Material medicine is made：1 part of 40 parts of fresh rehmannia root, 5 parts of fresh oriental wormwood, 5 parts of hawthorn, 5 parts of the Radix Astragali, 5 parts of fructus cannabis, 3 parts of almond and Radix Glycyrrhizae.
3. the Chinese medicinal liquor according to claim 1 with effect for reducing blood fat, it is characterised in that by following ratio of weight and number
Raw material is made：45 parts of glutinous rice, 68 parts of Chinese medicine, medicine is bent 27 parts, 4 parts of distiller's yeast；Described Chinese medicine is by the original of following ratio of weight and number
Material medicine is made：1 part of 45 parts of fresh rehmannia root, 6 parts of fresh oriental wormwood, 4 parts of hawthorn, 4 parts of the Radix Astragali, 4 parts of fructus cannabis, 4 parts of almond and Radix Glycyrrhizae.
4. the Chinese medicinal liquor according to claim 1 with effect for reducing blood fat, it is characterised in that by following ratio of weight and number
Raw material is made：50 parts of glutinous rice, 70 parts of Chinese medicine, medicine is bent 28 parts, 5 parts of distiller's yeast；Described Chinese medicine is by the original of following ratio of weight and number
Material medicine is made：1 part of 50 parts of fresh rehmannia root, 5 parts of fresh oriental wormwood, 4 parts of hawthorn, 3 parts of the Radix Astragali, 4 parts of fructus cannabis, 3 parts of almond and Radix Glycyrrhizae.
5. the preparation method of the Chinese medicinal liquor with effect for reducing blood fat described in claim 1 or any one of 2-4, it is characterised in that
Comprise the following steps：
1）Above-mentioned Chinese medicine is brewageed into the constitutive material with effect for reducing blood fat Chinese medicinal liquor just handle：
（a）Fresh rehmannia root, net system cuts sheet 3mm, puts and pulpous state is crushed in juice extractor, and squeeze and filter obtains fresh rehmannia root juice and the dregs of a decoction, treats
With；
（b）Fresh oriental wormwood, puts and pulpous state is crushed in juice extractor, and squeeze and filter obtains fresh Oriental wormwood juice, stand-by；
（c）Almond, net system, removal is gone mouldy product, put boiled in boiling water to skin it is micro- swollen when, pull out, slightly soaked with cold water, taken out, peeling point,
80 DEG C of dryings obtain benevolence, take benevolence to put in the machine for stir-frying Chinese medicine of preheating to constant weight in drying box, fry slightly yellow to showing with slow fire, slightly
Focal spot, has fragrance, taking-up to be crushed after cooling, crosses No. 1 sieve, and making drugs into frostlike powder of extracting oil obtains almond meal, stand-by；
（d）Fructus cannabis, net system is heated with slow fire, is fried to there is fragrance, in slightly yellow, is taken out, crushed after cooling, crosses No. 1 sieve, squeeze
Oily making drugs into frostlike powder, obtains fructus cannabis frost, stand-by；
（e）Drying removes moisture at 80 DEG C respectively for the Radix Astragali, hawthorn and Radix Glycyrrhizae, crushed No. 1 sieve, and obtained the Radix Astragali, hawthorn fruit；
2）Untill glutinous rice is dipped into easy two valve of hand stone roller in clear water, the glutinous rice soaked is rinsed well with running water, drained the water
It is rearmounted to be lined with the steaming in container of gauze, it is closed to steam to glutinous rice without the raw heart, it is loose not paste, thoroughly without rotten, untill uniformity,
Steamed glutinous rice is eluted with cold water, a little cold water is drenched while stirring, rice temperature is quickly down to 28-33 DEG C, obtains glutinous
Rice；
3）It is prepared by medicine song：By step 1）The fresh rehmannia root dregs of a decoction of preparation are mixed with wheat bran, flour, the fresh rehmannia root dregs of a decoction and wheat bran, flour
Weight ratio is 8：1：1, add water and be kneaded into agglomerate, be then charged into bent mold forming, curved billet is poured out, and hangs 1-3h, culture of entering the room, in training
Support and cultivate 24-36h in room, during which turned over 1 time every 4-6h, temperature control is at 30-37 DEG C, when temperature gradually decreases down 25-27 DEG C
When, that is, finished medicines song is obtained, it is standby；
4）By step 2）The glutinous rice of preparation, step 1）The fresh rehmannia root juice of middle Processing methods, fresh Oriental wormwood juice, hawthorn fruit, the Radix Astragali
Powder, fructus cannabis frost, almond meal and Radix Glycyrrhizae powder, step 3）The medicine Qu Junyu distiller's yeasts prepared are mixed and stirred for uniformly；
5）By above-mentioned steps 4）The mixture of gained is transferred in sterilized round, compacting mixture, smooth out surface, in
Between nest, sealing places in incubator and ferments 15-20 days, first progress solid fermentation-saccharifying, and temperature is maintained at 31-35
DEG C, turn over 1-4 times daily, fermentation is to when saccharification juice is at the high 3/5-4/5 in mixture surface, and after 5-7 days, add water 40-50
Part, secondary fermentation is carried out, turns over 1-3 times within 8-12 days, was turned over every 1 day 1 time daily within 13-20 days；
6）By above-mentioned steps 5）The fermenting mixture of gained carries out expression separation and obtains raw wine, and alcoholic strength is measured in 12-20 degree；
7）By above-mentioned steps 6）The raw wine of gained is decocted, after intense fire is fried boiling, then to be cooked by slow fire 5min, stands 24h, mistake
Filter, obtained filtrate is closed, carries out ageing 30 days, gets product Chinese medicinal liquor.
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