CN106943973A - The three-dimensional micro- integrated tower of reaction of hypergravity - Google Patents
The three-dimensional micro- integrated tower of reaction of hypergravity Download PDFInfo
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- CN106943973A CN106943973A CN201710237277.XA CN201710237277A CN106943973A CN 106943973 A CN106943973 A CN 106943973A CN 201710237277 A CN201710237277 A CN 201710237277A CN 106943973 A CN106943973 A CN 106943973A
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- tower body
- tower
- reaction
- microreactor
- feed liquid
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0006—Controlling or regulating processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/28—Moving reactors, e.g. rotary drums
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00049—Controlling or regulating processes
- B01J2219/00164—Controlling or regulating processes controlling the flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00889—Mixing
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00891—Feeding or evacuation
- B01J2219/00894—More than two inlets
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
The present invention relates to a kind of three-dimensional micro- integrated tower of reaction of hypergravity, including a housing, the housing central section sets the feed liquid passage for being laid with a tower body that can be pivoted, the tower body and reactant being provided to micro- reaction of reactant hybrid reaction and for microreactor;The tower body is divided into the tower body outer layer positioned at the tower body internal layer at center and on the outside of tower body internal layer by structure difference;The feed liquid passage and microreactor are laid on tower body internal layer and outer layer respectively with specific structure and mode.The tower utilizes super gravity field and the synergy enhancing mass and heat transfer and course of reaction of microreactor, overcome the end effect of traditional hypergravity equipment, with the increase of tower radius, the mixed effect of fluid will not decline, it is more preferable on the contrary, flow direction and speed of the precise control reactant in tower, realize that multiple courses of reaction are integrated in a tower, and adjustment tower height realizes the quick amplification of the low cost for the treatment of capacity.
Description
Technical field
The present invention relates to a kind of three-dimensional micro- integrated tower of reaction of hypergravity, applied to fields such as chemical industry, pharmacy, biology, light industrys,
Belong to supergravity technical field.
Background technology
High-gravity technology developmental research starts from late 1970s, and Elevated Gravity is found by a large number of researchers research
Surface tension between lower fluid seems insignificant in the presence of shearing force of the filler to fluid of high speed rotation, originally micro-
Liquid agglomerated together is separated rapidly in gravitational field, existing way of the liquid in packing area is rendered as droplet-like, liquid film
Shape and brin shape, so that alternate contact area increases sharply, quickly, alternate speed of related movement is also rapid for boundary renewal speed
Increase, therefore high-gravity technology has been applied to the fields such as chemical industry, pharmacy, biology, light industry since the invention, but there is following lack
Point:(1)There is end effect, with the increase of rotor radius, mass transfer or reaction efficiency be not linearly increasing;(2)With rotor
The increase of radius, rotor outer periphery has largely dry area, and fluid is not good in the alternate contact of rotor outer periphery and mixed effect;(3)
It is difficult to produce in enormous quantities or large scale amplification.
The content of the invention
In view of this, it is an object of the invention to provide a kind of good mixing effect, the low cost for the treatment of capacity can be achieved in efficiency high
The micro- integrated tower of reaction of three-dimensional hypergravity quickly amplified.
The present invention is realized using following scheme:A kind of micro- integrated tower of reaction of three-dimensional hypergravity, including a housing, the housing
Middle part, which is set, to be laid with a tower body that can be pivoted, the tower body to the microreactor of reactant hybrid reaction and to be micro-
Reactor provides the feed liquid passage of reactant.
Further, the tower body includes the tower body internal layer and the tower body outer layer on the outside of tower body internal layer positioned at center;
The microreactor is distributed on tower body outer layer, and the upper end or lower end of tower body internal layer are provided with least one reaction-ure inlet, institute
State and at least one set of feed liquid passage is provided with tower body internal layer, every group of feed liquid passage connects at least one reaction-ure inlet;Feed liquid is led to
The outlet in road is connected with the entrance of microreactor.
Further, the tower body outer layer vertically it is circumferential or axially simultaneously with circumferential array microreactor, it is described
By multigroup feed liquid passage, alternating array is formed tower body internal layer vertically, a kind of one group of reactant of feed liquid passage circulation, the feed liquid
Channel entrance is arranged on tower body upper end or lower end, and the feed liquid passage outlet is connected with the microreactor entrance of tower body outer layer.
Further, every group of feed liquid passage includes mainstream channel positioned at tower body internal layer end, level distribution vertically
Distribution channel and placed channel, the mainstream channel of every group of feed liquid passage are connected with corresponding reaction-ure inlet, and major flow
The located passage in road and each distribution channel serial communication with group, the distribution channel are connected with the entrance of microreactor,
The distribution channel of difference group is alternately arranged vertically.
Further, it is layered distribution that microreactor is axially disposed, and circumferentially arranged every layer of microreactor is axle pair
Claim distribution, each microreactor is provided with least one entrance and one outlet, with being passed through same reaction on the microreactor of layer
The entrance of thing is connected with same distribution channel.
Further, described tower body internal layer is set to rotating shaft, and housing is stretched out at rotating shaft two ends, and tower body outer layer is solidly set on rotating shaft
On.
Further, the tower body is assembled by cylindrical tower section piecemeal, each cylindrical tower section highly for 0.01m ~
1m。
Further, the tower body is using 3D printing technique, the plate art of printing, chemistry etch techniques, photoetching electroforming injection skill
Any of art, diamond-turning technology, line cutting technology, laser processing technology and ion beam fabrication technology technology process and
Into.
Further, the material of tower body is polymer light material.
Compared with prior art, the invention has the advantages that:
(1)This overcomes tradition overweight using super gravity field and the synergy enhancing mass and heat transfer and course of reaction of microreactor
The end effect of power equipment, with the increase of tower radius, the mixed effect of fluid will not decline, on the contrary more preferably;
(2)By tower body rotating speed, the position of the angle of passage and microreactor and angle come precise control reactant in tower
Flow direction and speed;
(3)Realize that multiple courses of reaction are integrated in a tower;
(4)The liquid outlet channel design layered oriented structure of tower body internal layer, logistics precisely and can be directed to up to tower body outer layer
Specified location;
(5)By module superposition regulation tower height, so as to easily adjust the quantity of micro- reaction group and passage group, so that at realization
The quick amplification of low cost of reason amount;
, below will be attached by specific embodiment and correlation for the objects, technical solutions and advantages of the present invention are more clearly understood
Figure, is described in further detail to the present invention.
Brief description of the drawings
Fig. 1 is embodiment of the present invention organigram;
Fig. 2 is microreactor exemplary plot in the embodiment of the present invention 1;
Fig. 3 is tower body internal layer construction exemplary plot in the embodiment of the present invention 1;
Fig. 4 is tower body internal layer construction exemplary plot in the embodiment of the present invention 2;
Fig. 5 is microreactor exemplary plot in the embodiment of the present invention 2;
Label declaration in figure:1- housings, 2- tower bodies internal layer, 3- tower bodies outer layer, 4- reaction-ure inlets, 5- main channels, 6- positioning are logical
Road, 7- distribution channels, 8- material liquid outlets, 9- sealing rings.
Embodiment
Embodiment 1:As shown in Fig. 1 ~ 3, a kind of three-dimensional micro- integrated tower of reaction of hypergravity, including a housing 1, the housing 1
Middle part, which is provided with, to be laid with the tower body that can be pivoted, the tower body to the microreactor of reactant hybrid reaction and to be micro-
Reactor provides the feed liquid passage of reactant;Microreactor can be arranged as required into different structure or shape, and reactant exists
Hybrid reaction in microreactor, simultaneously because the radial position residing for microreactor constructed by tower body is bigger, then it is suffered from
Mental and physical efforts are bigger, therefore with the increase of tower radius, the mixed effect of fluid will not decline, on the contrary more preferably, and reaction efficiency is high.
In the present embodiment, the tower body includes the tower body internal layer 2 and the tower body positioned at the outside of tower body internal layer 2 positioned at center
Outer layer 3;The microreactor is distributed on tower body outer layer 3, and the upper end or lower end of tower body internal layer 3 are provided with least one reactant
At least one set of feed liquid passage is provided with import 4, the tower body internal layer 2, every group of feed liquid passage connects a reaction-ure inlet 4,
The entrance of microreactor is located at the madial wall of tower body outer layer 3, and the outlet of microreactor is located at the lateral wall of tower body outer layer 3;Feed liquid passage
Outlet be connected with the entrance of microreactor.
In the present embodiment, the tower body outer layer vertically it is circumferential or axially simultaneously with circumferential array microreactor,
By multigroup feed liquid passage, alternating array is formed the tower body internal layer vertically, a kind of one group of reactant of feed liquid passage circulation, described
Feed liquid passage import is arranged on tower body upper end or lower end, and the feed liquid passage outlet is connected with the microreactor entrance of tower body outer layer
It is logical.
In the present embodiment, every group of feed liquid passage includes being located at the mainstream channel 5 of tower body internal layer end, vertically level point
The distribution channel 7 and placed channel 6 of cloth, the mainstream channel 5 of every group of feed liquid passage are connected with corresponding reaction-ure inlet 4, and
And the located passage 6 of mainstream channel 5 and each serial communication of distribution channel 7 with group, the axle of placed channel 6 and tower body internal layer 2
Heart line is parallel, and the distribution channel 7 is connected with the entrance of microreactor, and the distribution channel of difference group is alternately arranged vertically.
In the present embodiment, it is layered distribution that microreactor is axially disposed, and every layer of microreactor circumferentially symmetrically divides
Cloth, each microreactor is provided with least one entrance, be passed through on the microreactor of layer the entrance of same reaction thing with it is same
The connection of individual distribution channel, staggers with the entrance that differential responses thing is passed through on the microreactor of layer in axial location, with profit from it is different
The distribution channel connection of layer;Reactant needed for being conveyed by from distribution channel to microreactor, and reactant can precisely simultaneously
It is directed to the specified location up to tower body outer layer.
In the present embodiment, the bottom of housing 1 is provided with material liquid outlet 8.
In the present embodiment, described tower body internal layer is set to rotating shaft, and housing is stretched out at rotating shaft two ends, tower body internal layer passes through
Drive device driving rotation, tower body outer layer is arranged with close with housing two ends with tower body internal layer synchronous axial system, the both ends of tower body internal layer 2
Seal the sealing ring 9 coordinated.
In the present embodiment, the tower body is assembled by cylindrical tower section piecemeal, and each cylindrical tower section is highly
0.01m~1m;Fraction block structure can realize tower body modularization, and passage group and microreactor can be easily adjusted by adjusting tower height
The quantity of group, so as to realize the quick amplification of low cost for the treatment of capacity, passes through tower body rotating speed, the angle of passage and microreactor
Position and angle carry out flow direction and speed of the precise control logistics in tower.
In the present embodiment, the tower body is using 3D printing technique, the plate art of printing, chemistry etch techniques, photoetching electroforming note
Any of molding technology, diamond-turning technology, line cutting technology, laser processing technology and ion beam fabrication technology technology is processed
Form.
In the present embodiment, the material of tower body can be metal material or nonmetallic materials, can be according to difference
Thing system and operating mode use different materials, preferably polymer light material.
In the present embodiment, each reaction-ure inlet 4 in tower body internal layer two ends, two reaction-ure inlets each lead into reaction
Thing A and reactant B, each microreactor have two entrances, and microreactor is y-type structure, under the influence of centrifugal force,
Reactant with certain flow direction and flow velocity, to tower peripheric movement, and in the microreactor of tower body outer layer, react by completion, reactant C
Into housing, left after collection from material liquid outlet.
Embodiment 2:As shown in Fig. 4 ~ 5, in the present embodiment, tower body internal layer upper end has two reaction-ure inlets, tower body
Internal layer lower end has a reaction-ure inlet, and three reaction-ure inlets each lead into reactant A, reactant B and reactant C, tower
Microreactor on volume surrounding then has three entrances, and reactant A and the reactant B first hybrid reaction in microreactor are obtained
Reactant D again with reactant C hybrid reactions produce reactant E enter housing, left after collection from material liquid outlet.
The object, technical solutions and advantages of the present invention are further described by above-listed preferred embodiment, are answered
Understand, the foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, all essences in the present invention
God is with principle, and any modifications, equivalent substitutions and improvements made etc. should be included within the scope of the present invention.
Claims (9)
1. a kind of micro- integrated tower of reaction of three-dimensional hypergravity, it is characterised in that:Including a housing, the housing central section sets one can be around axle
It is laid with the tower body of rotation, the tower body to the microreactor of reactant hybrid reaction and provides reaction for microreactor
The feed liquid passage of thing.
2. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 1, it is characterised in that:The tower body is included in being located at
The tower body internal layer of the heart and the tower body outer layer on the outside of tower body internal layer;The microreactor is distributed on tower body outer layer, in tower body
The upper end or lower end of layer, which are provided with least one reaction-ure inlet, the tower body internal layer, is provided with least one set of feed liquid passage,
Every group of feed liquid passage connects at least one reaction-ure inlet;The outlet of feed liquid passage is connected with the entrance of microreactor.
3. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 2, it is characterised in that:The tower body outer layer is vertically
It is circumferential or axially simultaneously with circumferential array microreactor, the tower body internal layer is by multigroup feed liquid passage alternating array vertically
Form, a kind of one group of reactant of feed liquid passage circulation, the feed liquid passage import is arranged on tower body upper end or lower end, the feed liquid
Channel outlet is connected with the microreactor entrance of tower body outer layer.
4. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 2, it is characterised in that:Every group of feed liquid passage includes position
Mainstream channel, the distribution channel of level distribution vertically and placed channel in tower body internal layer end, the master of every group of feed liquid passage
Circulation road is connected with corresponding reaction-ure inlet, and the located passage of mainstream channel is connected with each distribution channel with group
Connection, the distribution channel is connected with the entrance of microreactor, and the distribution channel of difference group is alternately arranged vertically.
5. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 4, it is characterised in that:Microreactor is axially disposed
For layered distribution, every layer of microreactor is circumferentially arranged to be distributed for axial symmetry, and each microreactor is provided with least one and entered
Mouth and one outlet, are connected with the entrance that same reaction thing is passed through on the microreactor of layer with same distribution channel.
6. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 2, it is characterised in that:Described tower body internal layer is set
For rotating shaft, housing is stretched out at rotating shaft two ends, and tower body outer layer is solidly set in rotating shaft.
7. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 1 or 2, it is characterised in that:The tower body is by cylinder
Shape tower section piecemeal assembles, and each cylindrical tower section is highly 0.01m ~ 1m.
8. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 1 or 2, it is characterised in that:The tower body uses 3D
Printing technique, the plate art of printing, chemistry etch techniques, photoetching electroforming injection molding technology, diamond-turning technology, line cutting technology, laser
Any of process technology and ion beam fabrication technology technology are processed.
9. the micro- integrated tower of reaction of three-dimensional hypergravity according to claim 1 or 2, it is characterised in that:The material of tower body is height
Molecule light material.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108656556A (en) * | 2018-05-22 | 2018-10-16 | 中北大学 | The high-gravity rotating bed 3D printing method with structured packing with constant channel |
CN110883339A (en) * | 2018-09-10 | 2020-03-17 | 临沂大学 | Method for preparing superfine metal powder |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006064132A (en) * | 2004-08-30 | 2006-03-09 | Fuji Photo Film Co Ltd | Micro selector valve |
US20060160206A1 (en) * | 2002-12-02 | 2006-07-20 | Gyros Ab | Parallel prosessing of microfluidic devices |
US20100151560A1 (en) * | 2008-12-12 | 2010-06-17 | Wo Andrew M | Compact disk based platform for separating and detecting immunomagnetic bead labeled cells |
CN101784346A (en) * | 2007-07-06 | 2010-07-21 | M技术株式会社 | Liquid treating apparatus, and treating method |
US20120252105A1 (en) * | 2008-10-24 | 2012-10-04 | Bioprocessh20 Llc | Systems, apparatuses and methods of cultivating organisms and mitigation of gases |
CN203754678U (en) * | 2014-03-17 | 2014-08-06 | 昆明理工大学 | Micro-channel grease deacidification device |
CN104136373A (en) * | 2012-03-26 | 2014-11-05 | 协和化学工业株式会社 | Method for manufacturing hydrotalcite particles |
CN104535514A (en) * | 2014-12-26 | 2015-04-22 | 杭州霆科生物科技有限公司 | Micro-fluidic chip for detecting fluoride in water body and preparation method thereof |
CN204724039U (en) * | 2015-05-14 | 2015-10-28 | 华南师范大学 | A kind of centrifugal microfluidic control emulsifier unit |
CN105964314A (en) * | 2016-04-26 | 2016-09-28 | 杭州霆科生物科技有限公司 | Centrifugal type microfluidic chip electrochemical detection device |
-
2017
- 2017-04-12 CN CN201710237277.XA patent/CN106943973B/en active Active
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060160206A1 (en) * | 2002-12-02 | 2006-07-20 | Gyros Ab | Parallel prosessing of microfluidic devices |
JP2006064132A (en) * | 2004-08-30 | 2006-03-09 | Fuji Photo Film Co Ltd | Micro selector valve |
CN101784346A (en) * | 2007-07-06 | 2010-07-21 | M技术株式会社 | Liquid treating apparatus, and treating method |
US20120252105A1 (en) * | 2008-10-24 | 2012-10-04 | Bioprocessh20 Llc | Systems, apparatuses and methods of cultivating organisms and mitigation of gases |
US20100151560A1 (en) * | 2008-12-12 | 2010-06-17 | Wo Andrew M | Compact disk based platform for separating and detecting immunomagnetic bead labeled cells |
CN104136373A (en) * | 2012-03-26 | 2014-11-05 | 协和化学工业株式会社 | Method for manufacturing hydrotalcite particles |
CN203754678U (en) * | 2014-03-17 | 2014-08-06 | 昆明理工大学 | Micro-channel grease deacidification device |
CN104535514A (en) * | 2014-12-26 | 2015-04-22 | 杭州霆科生物科技有限公司 | Micro-fluidic chip for detecting fluoride in water body and preparation method thereof |
CN204724039U (en) * | 2015-05-14 | 2015-10-28 | 华南师范大学 | A kind of centrifugal microfluidic control emulsifier unit |
CN105964314A (en) * | 2016-04-26 | 2016-09-28 | 杭州霆科生物科技有限公司 | Centrifugal type microfluidic chip electrochemical detection device |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108656556A (en) * | 2018-05-22 | 2018-10-16 | 中北大学 | The high-gravity rotating bed 3D printing method with structured packing with constant channel |
CN108656556B (en) * | 2018-05-22 | 2020-04-10 | 中北大学 | 3D printing method of structured packing for super-gravity rotating bed with constant channel |
CN110883339A (en) * | 2018-09-10 | 2020-03-17 | 临沂大学 | Method for preparing superfine metal powder |
CN110883339B (en) * | 2018-09-10 | 2022-09-09 | 临沂大学 | Method for preparing superfine metal powder |
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