CN106943673A - A kind of sleep apnea monitoring treatment system - Google Patents
A kind of sleep apnea monitoring treatment system Download PDFInfo
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- CN106943673A CN106943673A CN201710299248.6A CN201710299248A CN106943673A CN 106943673 A CN106943673 A CN 106943673A CN 201710299248 A CN201710299248 A CN 201710299248A CN 106943673 A CN106943673 A CN 106943673A
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- air flow
- intensity
- respiratory air
- oxygen saturation
- egersimeter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4806—Sleep evaluation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6814—Head
- A61B5/682—Mouth, e.g., oral cavity; tongue; Lips; Teeth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6832—Means for maintaining contact with the body using adhesives
- A61B5/6833—Adhesive patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0492—Patch electrodes
Abstract
The present invention relates to medical equipment technical field, more particularly to a kind of sleep apnea monitoring treatment system.The monitoring treatment system includes the respiratory air flow monitor, the blood oxygen saturation monitoring device for detecting blood oxygen saturation, egersimeter and calculating control device for triggering electromyographic signal under the motion of human body genioglossus and reception chin for being used to sense respiratory air flow.Control device is calculated to be connected with respiratory air flow monitor and the communication of blood oxygen saturation monitoring device, to collect respiratory air flow signal and oxygen saturation signal, calculate control device to be connected with egersimeter, to control egersimeter triggering the motion of human body genioglossus and receiving switching between two functions of electromyographic signal under chin.Thus, monitoring treatment system of the invention can non-invasively, the appearance of easily monitoring sleep apnea situation, and can give and treat, also, the system has high security and applicability.
Description
Technical field
The present invention relates to medical equipment technical field, more particularly to a kind of sleep apnea monitoring treatment system.
Background technology
OSAS (OSAS) is a kind of to be caused because the upper respiratory tract partially or completely blocks
Common sleep breathing disorders.OSAS notable performance is that sleep cycle is disorderly.OSAS can cause normal sleep period seriously to be broken
Bad, body can not fully be rested in sleep, thus cause in the daytime spirit it is not enough, feel fatigue daytime, sleepy, blunt,
And memory, notice, judgment and vigilance power decline.It is likely to occur the diseases such as depression and anxiety, irritability, dry and hypertension
Shape.During apnea, it can also trigger the hypoxia at night and hypercapnia of recurrent exerbation, hypertension, coronary disease may be caused
The complication such as disease, diabetes and cranial vascular disease, or even there is night sudden death.Therefore OSAS is that a kind of have sleeping for potential lethal
Dormancy respiratory disorder.OSAS is mainly in the crowd of 40-60 Sui, and male is overweight, and the elderly is more conventional.Clinical symptoms is by loud
The sound of snoring, of short duration asthma and the apnea for continuing more than 10 seconds are alternately constituted, and apnea performance mouth and nose air-flow stops, but chest and abdomen
Formula breathing is still suffered from.
Research is had shown that, nerve impulse is produced by electro photoluminescence hypoglossal nerve, and its meat fiber dominated can be made to produce contraction,
Epithelium healing dilator based on genioglossus makes tongue body travel forward, and expands glossopharyngeum air flue, so as to reduce upper airway resistance, improves
OSAS patient at night hypoxemia, is improved sleep cycle structure, reaches that OSAS purpose is alleviated in treatment.At present, it is a variety of
The hypoglossal nerve apparatus of electro-stimulation of implanted by clinical verification or is carrying out clinical trial US and European is multinational.
Universal clinical effectiveness shows that the hypoglossal nerve apparatus of electro-stimulation of implanted can be carried out by implanted electrode to hypoglossal nerve
Electro photoluminescence, expansion air flue space avoids apnea, maintains blood oxygen saturation, improves the sleep of night OSAS patient.
But, operation implantable stimulation electrode is had to pass through using this treatment method of hypoglossal nerve electro photoluminescence of implanted,
It is a kind of invasive treatment method, there is certain risk and side effect.There is patient to occur in that in clinical test, after implant electrode
The serious adverse reaction to implanted device, shows as pain, swelling or infection, so as to have to take out implanted electrode.
Thus, the security and applicability of above-mentioned treatment method are all relatively low.
The content of the invention
(1) technical problem to be solved
In order to solve the above mentioned problem of prior art, the present invention provides a kind of high security and the sleep-respiratory of applicability is temporary
Stop monitoring treatment system.
(2) technical scheme
In order to achieve the above object, the main technical schemes that the present invention is used include：
The present invention provides a kind of sleep apnea monitoring treatment system, including：Tidal air for sensing respiratory air flow
Monitor is flowed, respiratory air flow monitor can export corresponding respiratory air flow signal；Blood oxygen for detecting blood oxygen saturation is satisfied
With degree monitor, blood oxygen saturation monitoring device can export corresponding oxygen saturation signal；For triggering human body genioglossus to transport
Egersimeter that is dynamic and receiving electromyographic signal under chin；Control device is calculated, control device and respiratory air flow monitor and blood is calculated
The communication connection of oxygen saturation monitor, to collect respiratory air flow signal and oxygen saturation signal, calculates control device and is pierced with electricity
Device connection is swashed, to control egersimeter to be cut between two functions of electromyographic signal under triggering the motion of human body genioglossus and reception chin
Change.
According to the present invention, calculate control device and be more than preset time or full in blood oxygen in the dwell time of respiratory air flow
Control egersimeter starts to draw when exceeding the intensity of preset ratio and respiratory air flow less than default air flow value with the drop-out value of degree
The motion of human body genioglossus is sent out, remaining time control egersimeter receives electromyographic signal under chin.
According to the present invention, calculate control device and persistently receive respiratory air flow signal and oxygen saturation signal, in tidal air
The dwell time of stream is more than preset time or exceedes preset ratio and the intensity of respiratory air flow in the drop-out value of blood oxygen saturation
During less than default air flow value, calculate control device control egersimeter start with electro photoluminescence human body hypoglossal nerve, and if
Respiratory air flow still occurs in prefixed time interval after each electro photoluminescence dwell time when reaching is more than preset time or blood oxygen
The drop-out value of saturation degree exceedes preset ratio and the intensity of respiratory air flow is less than the situation for presetting air flow value, then calculates control device
Control egersimeter starts with electro photoluminescence human body hypoglossal nerve again, wherein, calculate control device and control egersimeter to open simultaneously
Stimulus intensity when dynamic, the thorn of first time electro photoluminescence, afterwards each electro photoluminescence is carried out using preset standard intensity as stimulus intensity
Swash intensity increases on the basis of the stimulus intensity of a preceding electro photoluminescence according to preset rules, and stimulus intensity after increase is reached
During predetermined limit intensity, keep this stimulus intensity constant when this is with electro photoluminescence afterwards, and if being preset after this time electro photoluminescence
Respiratory air flow still occurs in time interval dwell time when reaching is more than preset time or the drop-out value of blood oxygen saturation exceedes
Preset ratio and the intensity of respiratory air flow are less than the situation of default air flow value, then calculate control device automatic alarm.
According to the present invention, monitoring treatment system also includes that the cardioelectric monitor device of electrocardiosignal, cardioelectric monitor device can be received
It is connected with calculating control device communication to transmit electrocardiosignal.
According to the present invention, calculating control device includes main frame and computing terminal that communication with one another is connected；Wherein, cardioelectric monitor
Device is cardioelectric monitor electrode, is fixed on the lower surface of main frame, main frame and respiratory air flow monitor, cardioelectric monitor device and egersimeter
Electromyographic signal under communication connection, main frame reception respiratory air flow signal, electrocardiosignal and chin, and be processed to be formed and computing terminal
Computing terminal is passed to after the signal of adaptation；Wherein, computing terminal is connected with blood oxygen saturation monitoring device communication, is calculated eventually
The dwell time held in respiratory air flow is more than preset time or exceedes preset ratio and breathing in the drop-out value of blood oxygen saturation
When the intensity of air-flow is less than default air flow value, enabled instruction is sent to main frame, main frame, which is received, controls electro photoluminescence after enabled instruction
Device starts with electro photoluminescence human body hypoglossal nerve, and if the prefixed time interval after each electro photoluminescence is still exhaled when reaching
The drop-out value that the dwell time of inspiratory flow is more than preset time or blood oxygen saturation exceedes the strong of preset ratio and respiratory air flow
Degree then calculates control device and sends enabled instruction to main frame again, main frame receives startup and referred to less than the situation of default air flow value
Egersimeter is controlled to start with electro photoluminescence human body hypoglossal nerve after order, wherein, computing terminal calculates thorn when egersimeter starts
Swash intensity and intensity instruction is sent to main frame, main frame instructs the stimulus intensity for controlling egersimeter according to intensity, wherein, calculate
Stimulus intensity of the terminal using preset standard intensity as first time electro photoluminescence, afterwards the stimulus intensity of each electro photoluminescence it is preceding once
Increase on the basis of the stimulus intensity of electro photoluminescence according to preset rules, stimulus intensity after increase reaches predetermined limit intensity
When, keep this stimulus intensity constant when this is with electro photoluminescence afterwards, and if prefixed time interval is reached after this time electro photoluminescence
When still there is respiratory air flow dwell time be more than the drop-out value of preset time or blood oxygen saturation and exceed preset ratio and exhale
The intensity of inspiratory flow is less than the situation of default air flow value, then computing terminal automatic alarm.
According to the present invention, main frame has battery power supply unit, and egersimeter includes two stimulating electrodes, and main frame is with stimulating electricity
Pole wired connection, for powered when stimulating electrode need to be started for stimulating electrode and under remaining Time Transmission chin myoelectricity believe
Number.
According to the present invention, preset rules are equivalent increase or gradient increase.
According to the present invention, respiratory air flow monitor and cardioelectric monitor device and host machine wired connection；Blood oxygen saturation monitoring device
With computing terminal wireless connection；Main frame and computing terminal wireless connection.
According to the present invention, computing terminal stores the respiratory air flow signal being adapted to it, oxygen saturation signal, electrocardiosignal
With electromyographic signal under chin；Computing terminal be provided be used to setting preset time, preset ratio, default air flow value, prefixed time interval,
The input of preset standard intensity, preset rules and predetermined limit intensity.
According to the present invention, cardioelectric monitor electrode and stimulating electrode are medical adhesive type surface electrode.
(3) beneficial effect
The beneficial effects of the invention are as follows：
First, directly carry out that electro photoluminescence is necessarily most directly effective to cause chin tongue to hypoglossal nerve using implanted electrode
Epithelium healing expansion based on flesh makes the mode that tongue body travels forward, but the security of implanted electrode and applicability are all relatively low.
In this regard, the present invention breaches implanted set-up mode, and using egersimeter, the sublingual god of correspondence in the case where the egersimeter is arranged on chin
During the position of warp, the electro photoluminescence of egersimeter output can equally cause tongue body to travel forward, and expand glossopharyngeum air flue, so as to reduce
Upper airway resistance.And this egersimeter set in vitro is noninvasive, the adverse reactions such as infection will not be caused, without
Operation, it is easy to operate, it is safe, it is applicable wide.
Secondly, the egersimeter in the present invention possesses the dual-use function of electromyographic signal detection and electro photoluminescence under chin.Need not
When triggering the motion of human body genioglossus, the system is in monitoring state, and electromyographic signal under the chin of collection can be made by calculating control device
Data etc. are assessed for sleep state, when needing to trigger the motion of human body genioglossus, trigger human body genioglossus to transport by egersimeter
It is dynamic.Thus, originally allow egersimeter to possess two functions and allow calculating control device to control egersimeter in two functions
Between switch, strengthen the function of the system while the structure for simplifying the system.
To sum up, sleep apnea monitoring treatment system of the invention can non-invasively, easily monitoring sleep breathes temporary
Stop the appearance of situation, and can give and treat, also, the system has high security and applicability.
Brief description of the drawings
The connection of the sleep apnea monitoring treatment system for the embodiment one that Fig. 1 provides for following embodiment is closed
It is schematic diagram；
Fig. 2 is the logic judgment flow chart in calculation control module in the sleep apnea monitoring treatment system in Fig. 1.
Embodiment
In order to preferably explain the present invention, in order to understand, below in conjunction with the accompanying drawings, by embodiment, to this hair
It is bright to be described in detail.
Embodiment one
Reference picture 1, provides a kind of sleep apnea monitoring treatment system in the present embodiment.The sleep apnea is supervised
Surveying treatment system includes respiratory air flow monitor, blood oxygen saturation monitoring device, egersimeter and calculates control device.
Specifically, respiratory air flow monitor is used to sense respiratory air flow and can export corresponding respiratory air flow signal, i.e.,
The relevant information of respiratory air flow signaling bearer respiratory air flow (at least including strength information).Blood oxygen saturation monitoring device is used to detect
Blood oxygen saturation simultaneously can export the number that corresponding oxygen saturation signal, i.e. oxygen saturation signal carry blood oxygen saturation
Value.Egersimeter has two functions, and one is to be used to trigger human body genioglossus to move, and another is to receive myoelectricity under chin to believe
Number.
Specifically, calculate control device to be connected with respiratory air flow monitor and the communication of blood oxygen saturation monitoring device, to collect
Respiratory air flow signal and oxygen saturation signal, calculate control device and are connected with egersimeter, to control egersimeter in initiation
Human body genioglossus is moved and received under chin to be switched between two functions of electromyographic signal.
The description of main body based on the above-mentioned sleep apnea monitoring treatment system to the present embodiment, it is known that the present embodiment
Monitoring treatment system have the following advantages that：
First, electro photoluminescence is directly carried out necessarily most directly effectively to hypoglossal nerve using implanted electrode in the prior art
The epithelium healing caused based on genioglossus the expansion mode that makes tongue body travel forward, but the security of implanted electrode and be applicable
Property is all relatively low.In this regard, the present embodiment breaches implanted set-up mode and uses egersimeter, chin is arranged in the egersimeter
During the hypoglossal position of lower correspondence, the electro photoluminescence of egersimeter output can equally cause tongue body to travel forward, and expand glossopharyngeum
Air flue, so as to reduce upper airway resistance.And this egersimeter set in vitro is noninvasive, infection etc. will not be caused no
Good reaction, it is easy to operate without operation, it is safe, it is applicable wide.
Second, the egersimeter in the present embodiment possesses the dual-use function of electromyographic signal detection and electro photoluminescence under chin.In nothing
When need to trigger the motion of human body genioglossus, the system is in monitoring state, and calculating control device can be by electromyographic signal under the chin of collection
Data etc. are assessed as sleep state, when needing to trigger the motion of human body genioglossus, human body genioglossus is triggered by egersimeter
Motion.Thus, originally allow egersimeter to possess two functions and allow calculating control device to control egersimeter in two work(
Switch between energy, strengthen the function of the system while the structure for simplifying the system.
To sum up, the sleep apnea monitoring treatment system of the present embodiment can non-invasively, easily monitoring sleep be breathed
The appearance of pause conditions, and can give and treat, also, the system has high security and applicability.
Further, calculate control device and be more than preset time or in blood oxygen saturation in the dwell time of respiratory air flow
Drop-out value exceed when the intensity of preset ratio and respiratory air flow is less than default air flow value and (now think apnea), control
Egersimeter processed starts to trigger human body genioglossus to move, remaining time (i.e. when above-mentioned apnea does not occur) control electricity thorn
Swash device and receive electromyographic signal under chin.
Thus, with the number of the intensity and blood oxygen saturation of the dwell time of respiratory air flow and respiratory air flow in the present embodiment
It is worth to trigger the double standards of electro photoluminescence, monitoring accuracy is high.Specifically, the stopping of respiratory air flow is to judge that apnea is most straight
The condition of sight, but it is also possible to occur air-flow and non-fully without but the state that remains at low levels, when such as patient is long
Between be in this state, it is possible that other diseases caused by the problems such as severe depletion of oxygen.Because respiratory air flow suspend or in compared with
Low-level can along with blood oxygen saturation decline, so using blood oxygen saturation measurement as judgement sleep apnea one
Individual index can prevent the appearance of above mentioned problem, and further, the reduction of blood oxygen saturation is not definitely that apnea is drawn
Rise, it is also possible to be due to caused by other diseases, so the numerical value conduct of the intensity and blood oxygen saturation with reference to respiratory air flow
Erroneous judgement can be prevented simultaneously by judging the subsidiary conditions of apnea.Thus, the sleep apnea monitoring treatment system of the present embodiment
Can in time, be accurately detected the situation for apnea occur, monitoring accuracy is high, and then can reduce treatment difficulty.
Therefore, the sleep apnea monitoring treatment system of the present embodiment can also effectively, monitor sleep exhale
The appearance of pause conditions is inhaled, and can give and timely and effectively treat, security and applicability are further enhanced.
Further, in the present embodiment, calculate control device and persistently receive respiratory air flow signal and oxygen saturation signal,
And specifically carry out following apnea decision process：
It is more than preset time in the dwell time of respiratory air flow or exceedes preset ratio in the drop-out value of blood oxygen saturation
And the intensity of respiratory air flow is when being less than default air flow value, it is believed that apnea, calculate control device control egersimeter start with
Electro photoluminescence human body hypoglossal nerve, and if still there is respiratory air flow when reaching in the prefixed time interval after each electro photoluminescence
Dwell time is more than preset time or the drop-out value of blood oxygen saturation exceedes the intensity of preset ratio and respiratory air flow less than pre-
If the situation of air flow value, then be considered as a preceding electro photoluminescence and do not work, then calculate control device and control egersimeter again
Start with electro photoluminescence human body hypoglossal nerve, wherein, stimulus intensity control device controls egersimeter startup simultaneously when is calculated, with
Preset standard intensity carries out first time electro photoluminescence, the stimulus intensity of each electro photoluminescence after first time electro photoluminescence as stimulus intensity
Increase on the basis of the stimulus intensity of a preceding electro photoluminescence according to preset rules, stimulus intensity after increase reaches default
During ultimate strength, it is constant that stimulus intensity is fixed on the value, forms final stimulus intensity, and this is kept in this and electro photoluminescence afterwards
Stimulus intensity (i.e. final stimulus intensity) is constant, i.e., carry out now corresponding stimulation work and thorn afterwards with final stimulus intensity
Swash work.And if when still occurring the dwell time of respiratory air flow when prefixed time interval is reached after this time electro photoluminescence more than presetting
Between or the drop-out value of blood oxygen saturation exceed the intensity of preset ratio and respiratory air flow and be less than the situation of default air flow value, i.e.,
Judge that the electro photoluminescence carried out for the first time with final stimulus intensity does not work, then calculate control device automatic alarm.To sum up, it can manage
Solution, calculation control module can trigger an electro photoluminescence when apnea occurs, and whenever bar of the electro photoluminescence because of apnea
When part is set up and is triggered, it can again be judged when prefixed time interval is reached, if apnea condition is still set up, be said
A bright preceding electro photoluminescence does not come into force, then increases stimulus intensity and carry out electro photoluminescence again, then when prefixed time interval is reached
Judged again, the like, until when there is the invalid situation of apnea condition, this group of electro photoluminescence terminates.
It should be noted that " holding in above-mentioned " calculate control device and persistently receive respiratory air flow signal and oxygen saturation signal "
It is continuous " mean in apnea decision process is carried out, calculate control device and still receive respiratory air flow signal and blood oxygen saturation
Spend signal.And the process that control device receives each signal is calculated, can be that the sampling site at interval is received or continuous reception,
It is not limited herein.
Thus, in the present embodiment, control device is calculated after apnea situation occurs in first time, after separated in time
Determine whether apnea situation occur again, to judge whether previous electro photoluminescence works, if do not worked, increase thorn
Sharp intensity is stimulated again, so laddering electro photoluminescence, while ensureing that patient obtains medical treatment, the stimulation suffered by it is strong
Degree control can so be avoided influenceing the sleep of patient, easily do not waken patient up in minimum.Further setting limit intensity,
When there is serious apnea situation, patient, its household are waken up by alarming in time or causes medical personnel to note, is made
Patient can be given treatment in time.
Specifically, preset rules during above-mentioned stimulus intensity increase are preferably equivalent increase or gradient increase, i.e. according to pre-
If constant incrementss increase, or according to the increase of default increasing degree.Certainly, the present invention is not limited to this, and other increase modes are equal
It is applicable.
Specifically, in the present embodiment, respiratory air flow monitor is fixed on below patient nostril, and it is non-to be placed on a volume
In often small container, it is not blocked with the respiratory air flow for ensureing patient, respiratory air flow monitor is with calculating the wired company of control device
Connect, to transmit respiratory air flow signal.Specifically, temperature sense resistance can be used in respiratory air flow monitor, and temperature sense resistance leads to
The air-flow that remarkable breathing is produced can cause breathing of the principle that local temperature changes to patient to be monitored in real time.Respiratory air flow is supervised
Survey device and pressure sensitive unit can also be used, when there is air-flow by above sensor because sensor surface air velocity changes
Change causes sensor pressure to change, and respiratory air flow can be monitored in real time using this principle.Certainly, respiratory air flow is monitored
Mode the above method can be used, but be not limited to both approaches, those skilled in the art can as needed can using other
Air-flow is monitored by mode.
In the present embodiment, blood oxygen saturation monitoring device mainly includes infrared finger arteries and veins oxygen detection means, radio communication unit
And battery power supply unit.Infrared finger arteries and veins oxygen detection means is clipped on patient's finger, and infrared finger arteries and veins oxygen detection means will be detected
Blood oxygen saturation information is transferred to calculating control device in the form of oxygen saturation signal by radio communication unit.Battery is supplied
Electric unit is mainly responsible for blood oxygen saturation monitoring device and powered, and battery level information can pass to calculating by radio communication unit
Control device, calculate control device can blood oxygen saturation monitoring device the not enough alarm of battery electric quantity, can also pass through and calculate control
Display screen in control equipment shows the battery electric quantity of blood oxygen saturation monitoring device.
Specifically, in the present embodiment, egersimeter includes two stimulating electrodes, and the stimulating electrode is fast changeable
Medical adhesive type surface electrode, its be provided simultaneously with receive chin under electromyographic signal and carry out electro photoluminescence dual-use function.Two thorns
Sharp electrode is respectively used to the bifurcation for being fixed on the both sides of human body chin portion center line, genioglossus being dominated corresponding to hypoglossal nerve, for example,
Apart from human body chin portion center line about 0.3cm, the position apart from lower jaw edge front end about 1.5cm.When certainly, for different patients, stimulate
The fixed position of electrode is slightly different, as long as being integrally fixed at can trigger human body genioglossus to move and receive electromyographic signal under chin
Position.Also, two stimulating electrodes with calculating control device wired connection, calculate control device and control two stimulation electricity
Pole is switched between two kinds of functions of electromyographic signal and electro photoluminescence under receiving chin, and the realization of control can be set using electronic control circuit
Fixed mode, is certainly not limited to this.
Further, monitoring treatment system may also include cardioelectric monitor device, and the cardioelectric monitor device is used to receive electrocardiosignal, the heart
Pyroelectric monitor device is connected to transmit electrocardiosignal with calculating control device communication.
In the present embodiment, cardioelectric monitor device be cardioelectric monitor electrode, preferably single channel cardioelectric monitor electrode and be can
Quick-replaceable medical adhesive type surface electrode a, lead of its functional equivalent in traditional cardioelectric monitor, is positioned over patient
Chest, can receive electrocardiosignal.
Further, in the present embodiment, calculating control device includes main frame and computing terminal, wherein, main frame is mainly used in
The reception and preliminary treatment of most of signal, computing terminal mainly undertake the judgement for calculating control device and control function.
Specifically, first, respiratory air flow monitor is communicated with main frame by way of wired connection is connected, and is exhaled with transmitting
Inspiratory flow signal；Computing terminal is communicated by way of wireless connection with blood oxygen saturation monitoring device and is connected, and is specially and blood oxygen
The radio communication unit connection of saturation monitor, the battery level information and oxygen saturation signal of blood oxygen saturation monitoring device
Computing terminal is sent to by radio communication unit, the burden beneficial to mitigation main frame is so provided with, and then is conducive to mitigating
The size of main frame；Cardioelectric monitor electrode is fixed on the lower surface of main frame, and cardioelectric monitor electrode is carried out by wired mode and main frame
Communication is to transmit electrocardiosignal, and on the one hand the setting that such cardioelectric monitor electrode is integrated with main frame does not have external electrical
Line, the work of cardioelectric monitor electrode will not be influenceed by actions such as turn-over bed for patient, on the other hand, the cardioelectric monitor electricity of adhesive type
Pole can be additionally used in fixed host computer；Stimulating electrode is connected with main frame by way of wired connection, on the one hand need to start stimulation electricity
During pole, main frame is powered for stimulating electrode, produces electro photoluminescence, on the other hand (need not start stimulating electrode to produce in remaining time
During electro photoluminescence) transmit electromyographic signal under chin.Main frame receives flesh under respiratory air flow signal, oxygen saturation signal, electrocardiosignal, chin
Electric signal, and by its signal that processing formation is adapted to computing terminal respectively, main frame is wirelessly communicated with computing terminal
Connection, will locate the signal transmission after preliminary reason to computing terminal.
Further, being directed on the structure of main frame, main frame has an integrated interface, for the monitoring of wired connection respiratory air flow
Device and egersimeter.Include inside main frame for the battery power supply unit powered, signal processing unit, electro photoluminescence generating unit and
Radio communication unit.Wherein, battery power supply unit is connected with signal processing unit, electro photoluminescence generating unit and radio communication unit
To power.Radio communication unit and respiratory air flow monitor, computing terminal, signal processing unit, to transmit each signal.Signal
Processing unit mainly completes the filtering process at initial stage to each signal, including removes Hz noise, signal amplification and sampling, finally leads to
Cross radio communication unit and each signal after preliminary treatment is sent to computing terminal, also, signal processing unit is also used for analysis
Handle each control signal from computing terminal received by radio communication unit.Electro photoluminescence generating unit is connect by integrated
Mouth and electric wire are connected with stimulating electrode, and the electric current of certain strength is produced when needing to stimulate.The electricity of the battery power supply unit of main frame
Pond information about power sends computing terminal to by radio communication unit.All elements of main frame are loaded in a jerrycan, electrocardio
Monitoring electrode is integrated in the lower surface of jerrycan, and container volume very little can be positioned over patient front, and very light weight will not make
Patient has compressing to feel.
In addition, above-mentioned electronic control circuit is contained in main frame, electronic control circuit and electro photoluminescence generating unit and signal
Processing unit is connected.Computing terminal is sent after enabled instruction to main frame, and signal processing unit makes Electronic Control according to enabled instruction
Circuit control stimulating electrode switches to electro photoluminescence function, after the certain time of enabled instruction is connected to, or in computing terminal hair
Go out after halt instruction, signal processing unit makes electronic control circuit control stimulating electrode to switch to the work(for receiving electromyographic signal under chin
Energy.
Further, computing terminal can be the external devices such as mobile phone, computer, and it has radio communication unit, is used for and main frame
Wireless connection.Therefore, computing terminal can be placed in away from patient elsewhere, will not hinder patient sleeps, and be conducive to
The attention for living family members or medical personnel together is reminded in time.
Wherein, computing terminal carries out following apnea decision process：
Computing terminal after the respiratory air flow signal being adapted to it and blood oxygen saturation that receive to analyzing, in breathing
The dwell time of air-flow is more than preset time or exceedes the strong of preset ratio and respiratory air flow in the drop-out value of blood oxygen saturation
When degree is less than default air flow value, enabled instruction is sent to main frame, main frame receive controlled after enabled instruction egersimeter start with
Electro photoluminescence human body hypoglossal nerve (is the electro photoluminescence generating unit generation electric current in main frame in the present embodiment, electric current is transferred to
Stimulating electrode produces electro photoluminescence), and preset if the dwell time for still occurring respiratory air flow after prefixed time interval is more than
The drop-out value of time or blood oxygen saturation exceedes preset ratio and the intensity of respiratory air flow is less than the situation for presetting air flow value,
Then calculate control device and send enabled instruction to main frame again, main frame, which is received, controlled after enabled instruction egersimeter startup with electricity
Human body hypoglossal nerve is stimulated, wherein, computing terminal calculates stimulus intensity when egersimeter starts and is sending enabled instruction
Intensity instruction is sent to main frame simultaneously, main frame instructs stimulus intensity when controlling the startup of this egersimeter according to intensity, its
In, stimulus intensity of the computing terminal using preset standard intensity as the stimulus intensity, afterwards each electro photoluminescence of first time electro photoluminescence
Increase on the basis of the stimulus intensity of a preceding electro photoluminescence according to preset rules, stimulus intensity after increase reaches default pole
When limiting intensity, it is constant that stimulus intensity is fixed on the value, forms final stimulus intensity, keeps this to pierce in this and electro photoluminescence afterwards
Sharp intensity (i.e. final stimulus intensity) is constant, i.e., carry out now corresponding stimulation work and stimulation afterwards with final stimulus intensity
Work.And if when still occurring the dwell time of respiratory air flow when prefixed time interval is reached after this time electro photoluminescence more than presetting
Between or the drop-out value of blood oxygen saturation exceed the intensity of preset ratio and respiratory air flow and be less than the situation of default air flow value, i.e.,
Judge for the first time with final stimulus intensity carry out electro photoluminescence do not work, then computing terminal automatic alarm (alarm can using sound,
The forms such as light, it is preferred to use form of sound).It is understood that can be reported automatically when being stimulated and not worked with final stimulus intensity
It is alert, but stimulate work not stop because of alarm.
Wherein, the regulation and control of stimulus intensity show the intensity size for the electric current that electro photoluminescence generating unit is produced, therefore, intensity
Instruction is that order console controller electro photoluminescence generating unit produces great electric current.In the present embodiment, because stimulus intensity is
It is adjustable, so when needing to carry out electro photoluminescence together, enabled instruction and intensity instruction supporting can be sent to master by computing terminal
Machine, main frame produces the electric current of corresponding size of current according to the two instruction control electro photoluminescence generating units.At the same time, for electricity
The electric current of stimulation is pulse current, and pulse current also relates to pulse length, pulse in addition to size of current this numerical value is related to
The parameters such as frequency, these parameters can be set in advance in main frame or computing terminal, be such as arranged in computing terminal, can be with intensity
Instruction is sent to main frame.
Further, computing terminal be provided be used to setting preset time, preset ratio, default air flow value, prefixed time interval,
The input of preset standard intensity, preset rules and predetermined limit intensity.Alternatively, above-mentioned pulse length, pulse frequency etc. have
Closing the parameter for the electric current for producing electro photoluminescence can also be set by input.
Wherein, for example, preset time is, for example, 5s, and preset ratio is, for example, 3%, and default air flow value is, for example,
60LPM, prefixed time interval is, for example, 5s, and the size of pulse current is, for example, 2mA, and pulse length is, for example, 0.5s, pulse frequency
Rate is, for example, 40Hz, and when preset rules increase according to equivalence, incrementss are, for example, 1mA.
Wherein, preset standard intensity and predetermined limit intensity can be inputted based on experience value, but are more usefully directed to
Each patient is tested to determine, detailed process is as follows：
First, two stimulating electrodes are respectively placed in outside the chin portion center line both sides of patient apart from center line about 0.3cm, distance
Lower jaw edge front end averagely about 1.5cm position.Open main frame and computing terminal, by it is above-mentioned with it is current related except size of current with
Outer parameter setting is good, determines that main frame is normal with computing terminal wireless connection, cell host electricity is sufficient.Adjusted by computing terminal
Economize on electricity stimulus intensity, intensity when tongue body sense of dragging forward occurs in patient is first measured under patient awoke's state, using this intensity as
The normal intensity of electro photoluminescence；The intensity of electric stimulus that measuring again makes patient feel during significant discomfort is the ultimate strength of electro photoluminescence.So
Afterwards, normal intensity and ultimate strength that above-mentioned experiment is obtained are inputted in the input of computing terminal, the two is respectively as pre- bidding
Quasi- intensity and predetermined limit intensity.Wherein, in the case where being set with the current related parameter in addition to size of current,
The size of electric current be with stimulus intensity it is one-to-one, therefore, preset standard intensity, predetermined limit intensity and preset rules for etc.
Incrementss during value increase can be showed with size of current.Certainly, the present invention is not limited to this, about the parameter of stimulus intensity
It can be characterized with other data.
In addition, computing terminal can also be to electromyographic signal under respiratory air flow signal, electrocardiosignal, oxygen saturation signal and chin
Deep signal analysis is carried out respectively, is extracted main useful signal and in the display screen display of computing terminal, is carried out simultaneously
Arrange and record storage, wherein, the heart working shape of user in sleep can be obtained from electromyographic signal under electrocardiosignal, chin
State, thoracic cavity and lower chin moving situation, more references are provided for sleep state analysis.Meanwhile, computing terminal can record electric thorn
Sharp information, shows electrical stimulation waveforms, stimulus intensity and stimulation time in real time on the display screen of computing terminal.Computing terminal has
There are network access functions, record information can be transferred in network data base.Computing terminal can suffer from so that automatic storage generation is each
The personal record message file of person.Computing terminal can monitor and display system in all battery power supply units battery electric quantity,
And provide warning message in not enough power supply.
In addition, the present invention main frame be not limited to only with above-mentioned respiratory air flow monitor, egersimeter and cardioelectric monitor device
Connection, the radio communication unit and integrated interface that main frame has can by way of wirelessly or non-wirelessly with other NM prisons
Device connection is surveyed, is used for the data of sleep apnea monitoring treatment to receive other, and calculating is given eventually by these data transfers
End.
To sum up, before monitoring, the mode that the monitoring treatment system is fixed on a patient body is：
Main frame is fixed on the chest muscle of patient by being integrated in the cardioelectric monitor electrode of the adhesive type on its surface.Will breathing
Airflow monitors are fixed on below the nostril of patient, 2 stimulating electrodes are fixed on to the both sides of the chin portion center line of patient, apart from people
Body chin portion center line about 0.3cm, the position apart from lower jaw edge front end about 1.5cm.Respiratory air flow monitor and stimulating electrode are passed through
Connecting line is connected with main frame, and connecting line is fixed on into patient body-surface by ad hoc approach.Blood oxygen saturation detection means is pressed from both sides
On patient's finger.
Further, in the present embodiment, the apnea decision process in reference picture 2, computing terminal can be：
S1, judge that whether the dwell time of respiratory air flow is more than preset time, or whether blood oxygen saturation drop-out value surpass
Cross preset ratio and whether respiratory air flow intensity is less than default air flow value, if so, step S2 is then performed, if it is not, then continuing executing with
Step S1；
S2, control egersimeter start, and stimulus intensity is execution step S3 after preset standard intensity, preset interval time；
S3, judge that whether the dwell time of respiratory air flow is more than preset time, or whether blood oxygen saturation drop-out value surpass
Cross preset ratio and whether respiratory air flow intensity is less than default air flow value, if so, step S4 is then performed, if it is not, then return to step
S1；
S4, stimulus intensity is increase on the basis of the stimulus intensity of a preceding electro photoluminescence according to preset rules, if increase
Stimulus intensity afterwards does not reach predetermined limit intensity, then with this stimulus intensity electro photoluminescence human body hypoglossal nerve, and between default
Every return to step S3 after the time, if the stimulus intensity after increase reaches predetermined limit intensity, with this stimulus intensity electro photoluminescence human body
Step S5 is performed after hypoglossal nerve, preset interval time；
S5, judge that whether the dwell time of respiratory air flow is more than preset time, or whether blood oxygen saturation drop-out value surpass
Cross preset ratio and whether respiratory air flow intensity is less than default air flow value, if so, step S6 is then performed, if it is not, then return to step
S1；
Stimulus intensity electro photoluminescence human body hypoglossal nerve automatic alarm, and pre- simultaneously when S4, a former electro photoluminescence
If return to step S5 after interval time.
Above content is only presently preferred embodiments of the present invention, for one of ordinary skill in the art, according to the present invention's
Thought, will change in specific embodiments and applications, and this specification content should not be construed as to the present invention
Limitation.
Claims (10)
1. a kind of sleep apnea monitoring treatment system, it is characterised in that including：
Respiratory air flow monitor for sensing respiratory air flow, the respiratory air flow monitor can export corresponding respiratory air flow
Signal；
Blood oxygen saturation monitoring device for detecting blood oxygen saturation, the blood oxygen saturation monitoring device can export corresponding blood
Oxygen saturation signal；
For triggering human body genioglossus to move and receiving the egersimeter of electromyographic signal under chin；
Control device is calculated, the calculating control device and the respiratory air flow monitor and the blood oxygen saturation monitoring device are logical
News connection, to collect the respiratory air flow signal and the oxygen saturation signal, the calculating control device is pierced with the electricity
Swash device connection, with control the egersimeter trigger human body genioglossus motion and receive chin under electromyographic signal two functions it
Between switch.
2. sleep apnea monitoring treatment system according to claim 1, it is characterised in that
The control device that calculates is more than preset time or the drop-out value in blood oxygen saturation in the dwell time of respiratory air flow
The egersimeter is controlled to start to trigger human body chin when being less than default air flow value more than preset ratio and the intensity of respiratory air flow
Lingualis is moved, and egersimeter described in remaining time control receives electromyographic signal under chin.
3. sleep apnea monitoring treatment system according to claim 2, it is characterised in that
The calculating control device persistently receives the respiratory air flow signal and the oxygen saturation signal, in respiratory air flow
Dwell time is more than preset time or is less than in the drop-out value of blood oxygen saturation more than the intensity of preset ratio and respiratory air flow
During default air flow value, the calculating control device controls the egersimeter to start with electro photoluminescence human body hypoglossal nerve, and such as
Prefixed time interval of the fruit after each electro photoluminescence still occur when reaching respiratory air flow dwell time be more than preset time or
The drop-out value of blood oxygen saturation exceedes preset ratio and the intensity of respiratory air flow is less than the situation for presetting air flow value, then described to calculate
Egersimeter described in secondary control starts with electro photoluminescence human body hypoglossal nerve control device again, wherein, the calculating control device is same
When stimulus intensity when controlling the egersimeter to start, electricity thorn for the first time is carried out using preset standard intensity as stimulus intensity
Swash, the stimulus intensity of each electro photoluminescence increases on the basis of the stimulus intensity of a preceding electro photoluminescence according to preset rules afterwards,
When the stimulus intensity after increase reaches predetermined limit intensity, keep this stimulus intensity constant when this is with electro photoluminescence afterwards,
And still occur when this time if prefixed time interval is reached after electro photoluminescence the dwell time of respiratory air flow be more than preset time or
The drop-out value of blood oxygen saturation exceedes preset ratio and the intensity of respiratory air flow is less than the situation for presetting air flow value, then described to calculate
Control device automatic alarm.
4. sleep apnea monitoring treatment system according to claim 3, it is characterised in that
The monitoring treatment system also includes that the cardioelectric monitor device of electrocardiosignal, the cardioelectric monitor device and the meter can be received
Control device communication connection is calculated to transmit the electrocardiosignal.
5. sleep apnea monitoring treatment system according to claim 4, it is characterised in that
The control device that calculates includes main frame and computing terminal that communication with one another is connected；
Wherein, the cardioelectric monitor device is cardioelectric monitor electrode, is fixed on the lower surface of the main frame, the main frame is exhaled with described
Inspiratory flow monitor, the cardioelectric monitor device and egersimeter communication connection, the main frame receive the respiratory air flow letter
Number, electromyographic signal under the electrocardiosignal and the chin, and be processed to be formed after the signal being adapted to the computing terminal and pass
Pass the computing terminal；
Wherein, the computing terminal is connected with blood oxygen saturation monitoring device communication, and the computing terminal is in respiratory air flow
Dwell time is more than preset time or is less than in the drop-out value of blood oxygen saturation more than the intensity of preset ratio and respiratory air flow
During default air flow value, enabled instruction is sent to the main frame, the main frame, which is received, controlled after enabled instruction the egersimeter
Start with electro photoluminescence human body hypoglossal nerve, and if the prefixed time interval after each electro photoluminescence is still breathed when reaching
The dwell time of air-flow is more than preset time or the drop-out value of blood oxygen saturation exceedes preset ratio and the intensity of respiratory air flow
Less than the situation of default air flow value, then the calculating control device is again to main frame transmission enabled instruction, and the main frame connects
Receive and controlled after enabled instruction the egersimeter startup with electro photoluminescence human body hypoglossal nerve, wherein, the computing terminal is calculated
Intensity instruction is simultaneously sent to the main frame by stimulus intensity when the egersimeter starts, and the main frame refers to according to the intensity
The stimulus intensity of the order control egersimeter, wherein, the computing terminal is used as first time electro photoluminescence using preset standard intensity
Stimulus intensity, afterwards the stimulus intensity of each electro photoluminescence on the basis of the stimulus intensity of a preceding electro photoluminescence according to default rule
Then increase, when the stimulus intensity after increase reaches predetermined limit intensity, keep this to stimulate when this is with electro photoluminescence afterwards strong
Degree is constant, and if when still occurring the dwell time of respiratory air flow when this time prefixed time interval is reached after electro photoluminescence and being more than default
Between or the drop-out value of blood oxygen saturation exceed the intensity of preset ratio and respiratory air flow and be less than the situation of default air flow value, then
The computing terminal automatic alarm.
6. sleep apnea monitoring treatment system according to claim 5, it is characterised in that
The main frame has battery power supply unit, and the egersimeter includes two stimulating electrodes, and the main frame is stimulated with described
Electrode wired connection, for being powered and described in remaining Time Transmission for the stimulating electrode when stimulating electrode need to be started
Electromyographic signal under chin.
7. the sleep apnea monitoring treatment system according to claim 3 or 5, it is characterised in that
The preset rules are equivalent increase or gradient increase.
8. sleep apnea monitoring treatment system according to claim 5, it is characterised in that
The respiratory air flow monitor and the cardioelectric monitor device and the host machine wired connection；
The blood oxygen saturation monitoring device and the computing terminal wireless connection；
The main frame and the computing terminal wireless connection.
9. sleep apnea monitoring treatment system according to claim 5, it is characterised in that
Myoelectricity under respiratory air flow signal, oxygen saturation signal, electrocardiosignal and chin that the computing terminal storage is adapted to it
Signal；
The computing terminal, which is provided with, to be used to set preset time, preset ratio, default air flow value, prefixed time interval, pre- bidding
The input of quasi- intensity, preset rules and predetermined limit intensity.
10. sleep apnea monitoring treatment system according to claim 6, it is characterised in that
The cardioelectric monitor electrode and the stimulating electrode are medical adhesive type surface electrode.
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| CN201710299248.6A CN106943673A (en) | 2017-04-28 | 2017-04-28 | A kind of sleep apnea monitoring treatment system |
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| CN109924964A (en) * | 2019-04-16 | 2019-06-25 | 烟台凯富医疗科技有限公司 | A kind of method and system for preventing sleep apnea based on Lower jaw support |
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| CN110353874A (en) * | 2019-08-01 | 2019-10-22 | 丽水澳中医疗设备有限公司 | A kind of sleep disordered breathing treatment system |
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