CN111068178A - Phrenic nerve stimulator control method, device and system - Google Patents
Phrenic nerve stimulator control method, device and system Download PDFInfo
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- CN111068178A CN111068178A CN201911421209.4A CN201911421209A CN111068178A CN 111068178 A CN111068178 A CN 111068178A CN 201911421209 A CN201911421209 A CN 201911421209A CN 111068178 A CN111068178 A CN 111068178A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/3611—Respiration control
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
- A61N1/36139—Control systems using physiological parameters with automatic adjustment
Abstract
The invention provides a phrenic nerve stimulator control method, a device and a system, which are used for acquiring physiological parameters of a patient when the phrenic nerve of the patient is stimulated, determining whether the current physiological state of the patient is abnormal or not by judging whether the physiological parameters reach a threshold value or not, further acquiring the myoelectric information of the diaphragm of the patient when the physiological state is abnormal, determining the phrenic nerve state through the information, and then executing a stimulation action suitable for the current phrenic nerve state, so that self-adaptive regulation of the stimulation action by equipment when the vital signs of the patient are changed is realized, and the device has strong convenience.
Description
Technical Field
The invention relates to the field of implantable medical devices, in particular to a phrenic nerve stimulator control method, device and system.
Background
In 1972, Glenn et al used a phrenic nerve stimulator for the first time and succeeded in improving respiratory function in patients with high neck marrow injury. The clinical application examples of the phrenic nerve stimulator continue to extend, and mainly include: central lung hypoventilation, sleep apnea syndrome (including Biot's breathing), brain stem injury or disease leads to respiratory failure, high cervical spinal cord injury or disease loses spontaneous breathing. Compared to mechanical ventilation, phrenic nerve stimulators have the advantage that (1) ventilation is closer to physiological ventilation mode, peripheral and lung floor tissues are well ventilated; (2) the mobility of the patient can be increased, and the patient can return to the society at an early stage; (3) the patient can eat and drink more conveniently, and can obtain normal breathing and pronunciation; (4) the inhaled gas passes through the nasal cavity, which is beneficial to the recovery or preservation of smell; (5) the incidence rate of complications such as pneumonia related to a respirator is reduced; (6) in addition, the medical cost can be reduced.
At present, the most widely used type of diaphragm pacemaker is Avery series, which has been developed to the 4 th generation, the clinical application time is longest, the number of cases is the most, and the corresponding technology is mature. Such pacemakers generate radio frequency signals from an external radio frequency transmitter, which are conducted by leads attached to the patient's body to a bi-directional receiver implanted subcutaneously. The analog circuit of the receiver converts the radio frequency signal into analog pulse, and the analog pulse is transmitted to an electrode implanted on the surface of the phrenic nerve through a lead to stimulate the phrenic nerve so as to generate respiration. The stimulator is externally hung, the external emitter bears all control functions, and when vital signs (such as pulse, blood oxygen saturation and respiratory frequency) of a patient are changed, a professional is required to adjust stimulation parameters of the respiratory pacemaker, so that the convenience is poor.
Disclosure of Invention
In view of the above, the present invention provides a method for controlling a phrenic nerve stimulator, comprising:
acquiring a physiological parameter;
judging whether the physiological parameter reaches a first threshold value;
acquiring myoelectric information when the physiological parameter reaches a first threshold value;
and determining the phrenic nerve state according to the myoelectric information and executing corresponding stimulation actions.
Optionally, the phrenic nerve state comprises at least a tired state and a non-tired state; the stimulation action corresponding to the fatigue state is to change a stimulation part, and the stimulation action corresponding to the non-fatigue state is to adjust a stimulation parameter according to a physiological parameter.
Optionally, the controlled implantable phrenic nerve stimulator comprises two groups of stimulation electrodes, wherein the two groups of stimulation electrodes are respectively used for stimulating phrenic nerves on two sides of a human body, only one group of stimulation electrodes outputs stimulation signals at the same time, and the change of the stimulation position is to switch the other group of stimulation electrodes to output the stimulation signals.
Optionally, the stimulation parameter comprises a stimulation frequency.
Optionally, the method further comprises:
judging whether the physiological parameter reaches a second threshold value;
when the physiological parameter reaches a second threshold value, an alarm action is executed.
Optionally, the method is performed by an extracorporeal device, which performs the corresponding stimulation action by sending a control signal to the implantable phrenic nerve stimulator.
Optionally, the physiological parameter comprises at least one of heart rate, blood oxygen saturation, respiratory parameter.
The invention also provides a control device of the phrenic nerve stimulator, which is suitable for being configured on the body surface of a human body, and the device comprises:
the physiological parameter sensor is used for acquiring the physiological parameters of the wearer in real time; the diaphragm myoelectricity sensor, the processor and the communication module are connected with the external power supply; the processor is used for judging whether the physiological parameter reaches a first threshold value in real time, starting the diaphragm myoelectric sensor to collect myoelectric information when the physiological parameter reaches the first threshold value, determining the state of the phrenic nerve according to the myoelectric information, and controlling the implanted type phrenic nerve stimulator to execute corresponding stimulation actions through the communication module.
Optionally, the phrenic nerve state comprises at least a tired state and a non-tired state; the stimulation action corresponding to the fatigue state is to change a stimulation part, and the stimulation action corresponding to the non-fatigue state is to adjust a stimulation parameter according to a physiological parameter.
Optionally, the stimulation parameter comprises a stimulation frequency.
Optionally, the processor is further configured to determine whether the physiological parameter reaches a second threshold, and execute an alarm action through the communication module when the physiological parameter reaches the second threshold.
Optionally, the physiological parameter sensor comprises at least one of a heart rate sensor, a blood oxygen saturation sensor, a respiration sensor.
The present invention also provides an implantable phrenic nerve stimulation system comprising: the control device and the implantable phrenic nerve stimulator.
Optionally, the implantable phrenic nerve stimulator includes two groups of stimulation electrodes, each of the two groups of stimulation electrodes is used for stimulating phrenic nerves on two sides of a human body, only one of the groups of stimulation electrodes outputs a stimulation signal at the same time, and the change of the stimulation position is to switch the other group of stimulation electrodes to output the stimulation signal.
According to the phrenic nerve stimulator control method, the device and the system provided by the embodiment of the invention, the physiological parameters of the patient are obtained when the phrenic nerve of the patient is stimulated, whether the current physiological state of the patient is abnormal is determined by judging whether the physiological parameters reach the threshold value, then the phrenic muscle electromyographic information of the patient is obtained when the physiological state is abnormal, the phrenic nerve state is determined through the information, and then the stimulation action suitable for the current phrenic nerve state is executed, so that the self-adaptive adjustment of the stimulation action of equipment is realized when the vital sign of the patient is changed without the participation of professionals, and the method, the device and the system have strong convenience.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.
FIG. 1 is a flow chart of a phrenic nerve stimulation method in an embodiment of the present invention;
FIG. 2 is a flow chart of another phrenic nerve stimulation method in an embodiment of the present invention;
FIG. 3 is a schematic diagram of a phrenic nerve stimulation system in an embodiment of the present invention;
fig. 4 is a schematic diagram of a control device in an embodiment of the invention.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
The embodiment of the invention provides a control method of a phrenic nerve stimulator, which can be executed by an implanted or non-implanted phrenic nerve stimulator or by an extracorporeal device used for controlling the stimulator. As shown in fig. 1, the method comprises the following steps:
s1, acquiring physiological parameters, specifically acquiring one or more parameters, such as heart rate, blood oxygen, respiratory rate, respiratory amplitude, respiratory cycle, etc., which may be acquired by sensors disposed inside or outside the user.
And S2, judging whether the physiological parameter reaches a first threshold value. And executing the step S3 when the physiological parameter reaches the first threshold, otherwise returning to the step S1 to continue monitoring. When the user meets the conditions of the step, the abnormal physiological state of the user is represented through the basic physiological parameters, and when the heart rate, the blood oxygen and the respiration related parameters reach the related abnormal threshold values, the abnormal physiological state of the user is represented.
In an alternative embodiment, only the blood oxygen saturation level is obtained and determined whether it is lower than the first saturation threshold, and step S3 is executed when the blood oxygen saturation level is lower than the first saturation threshold, otherwise, the monitoring is continued by returning to step S1.
In another alternative embodiment, only the heart rate is obtained and determined whether it is higher than the first heart rate threshold, and step S3 is executed when the heart rate is higher than the first heart rate threshold, otherwise, the monitoring is continued by returning to step S1.
In a third alternative embodiment, a plurality of physiological parameters, such as heart rate and blood oxygen saturation, may be acquired simultaneously, and step S3 is executed when two conditions, that is, the blood oxygen saturation is lower than the first saturation threshold and the heart rate is higher than the first heart rate threshold, otherwise, the monitoring is continued by returning to step S1; step S3 may also be executed when either of these two conditions is satisfied, otherwise, the monitoring is continued by returning to step S1.
The meaning of "reached" in step S2 may thus be interpreted as being higher than, lower than or equal to, depending on the kind of physiological parameter and its corresponding threshold value.
And S3, acquiring electromyographic information, specifically diaphragm electromyography, and acquiring the electromyographic information through a sensor arranged in or outside the body of the user.
And S4, determining the phrenic nerve state according to the electromyographic information and executing corresponding stimulation action. Various diaphragm or phrenic nerve states, such as diaphragm paralysis, diaphragm spasm, diaphragm fatigue, normality and the like, can be judged through the diaphragm myoelectric information. The appropriate stimulation actions are configured for different states in order to relieve or eliminate corresponding abnormal symptoms or make the user feel more comfortable and more in line with physiological patterns.
For an in-vivo or in-vitro stimulator capable of independently executing the method, corresponding stimulation actions can be executed by autonomously changing related parameters; for the case where the method is performed by the extracorporeal device and the stimulator in cooperation, the parameters corresponding to the stimulation action are determined by the extracorporeal device and then sent to the stimulator to perform the stimulation action in step S4.
According to the control method of the phrenic nerve stimulator, provided by the embodiment of the invention, the physiological parameters of the patient are obtained when the phrenic nerve of the patient is stimulated, whether the current physiological state of the patient is abnormal is determined by judging whether the physiological parameters reach the threshold value, then the myoelectric information of the diaphragm of the patient is obtained when the physiological state is abnormal, the phrenic nerve state is determined through the information, and then the stimulation action suitable for the current phrenic nerve state is executed, so that the self-adaptive adjustment of the stimulation action by equipment is realized when the vital signs of the patient are changed, the participation of professionals is not needed, and the control method has strong convenience.
In a preferred embodiment, at least the diaphragm fatigue state or the non-fatigue state is determined through step S4. Further, the stimulation action corresponding to the fatigue state is to change the stimulation site, which is related to the number and position of electrodes of the stimulator. The stimulator should have multiple or multiple sets of electrodes, each for stimulating a different diaphragm region of the human body, and there is at least one or one set of electrodes that does not output a stimulation signal at any one time. When the diaphragm fatigue state occurs, that is, the currently stimulated diaphragm part is fatigued, thus changing to stimulation of another position, thereby relieving or eliminating the fatigue state. Therefore, the embodiment can at least relieve or eliminate diaphragm fatigue generated when the diaphragm is stimulated.
By way of example, the implantable phrenic nerve stimulator comprises two groups of stimulation electrodes, wherein the two groups of stimulation electrodes are respectively used for stimulating phrenic nerves on two sides of a human body, only one group of stimulation electrodes outputs stimulation signals at the same time, and the stimulation position is changed by switching the other group of stimulation electrodes to output the stimulation signals, namely, the stimulation is adjusted to the contralateral side.
The stimulation action corresponding to the non-fatigue state is to adjust the stimulation parameters according to the physiological parameters. It should be noted that the non-fatigue state is not equal to the normal state, because it is determined in step S2 that the physiological parameter reaches the abnormal threshold value before proceeding to this step, the non-fatigue state should be understood in a broader sense, such as increasing/decreasing the activity amount, sleeping/waking state, taking medicine, etc., which indicates that the physiological parameter abnormality is not caused by diaphragm fatigue. However, in this embodiment, it is not necessary to distinguish between the specific states, and only two states, namely fatigue and non-fatigue, may be determined.
The stimulation parameters comprise various parameters such as pulse width, stimulation frequency and stimulation period, and the effect of changing the stimulation strength, the stimulation time and the like can be achieved by changing the parameters, so that the aim of improving the stimulation effect is fulfilled. The stimulation parameters may be adjusted according to one or more physiological parameters of heart rate, blood oxygen, and respiration-related parameters, for example, when the heart rate is higher, the stimulation frequency may be decreased, the stimulation period may be increased, and the like, and the specific adjustment manner may be various.
In a preferred embodiment, as shown in fig. 2, on the basis of the above embodiment, the method may further include the following steps:
s5, judging whether the physiological parameter reaches the second threshold value, and executing the step S6 when the physiological parameter reaches the second threshold value. Specifically, step S5 is similar to step S2, but the condition of step S5 indicates a worse case, such as 90% for the first threshold and 60% for the physiological parameter of blood oxygen saturation. Therefore, step S2 may be executed first, and when the blood oxygen saturation is lower than 90%, it is further determined whether it is lower than 60%, if it is lower than 60%, step S6 is executed while step S3 is also executed, otherwise, step S6 is not necessarily executed and only step S3 is executed;
for example, for a physiological parameter such as heart rate, the first threshold is 100 and the second threshold is 120. Therefore, step S2 can be executed first, when the heart rate is higher than 100, it is further determined whether it is higher than 120, if so, step S6 is executed while step S3 is also executed, otherwise, step S6 is not executed and only step S3 is executed; other types of physiological parameters are similar and will not be described in detail herein.
In other possible embodiments, step S5 and step S2 may be executed completely synchronously without any order difference, or step S5 may be executed first and then step S2 may be executed. Therefore, the above description and the case shown in fig. 2 are only examples for explaining the meaning of the first threshold and the second threshold, and do not limit the magnitude relationship between the first threshold and the second threshold or the execution sequence of step S5 and step S2.
And S6, executing an alarm action. The alarm action is, for example, a device executing the method performs voice prompt or displays related content; if the method is performed by an implanted device, a more suitable alarm action is to send an alert message to an external device. The purpose of executing the alarm action is to facilitate the patient to see a doctor in time, discover hidden dangers as early as possible and inform others to rescue. By way of example, information such as patient user information, addresses, emergency contact information and the like can be pre-entered, and emergency contacts can be contacted to seek help when an alarm action needs to be performed. According to the preferred scheme, the safety of the patient can be ensured to the greatest extent under the condition of simulating the respiratory physiology, the patient can see a doctor in time conveniently, and hidden dangers can be found as early as possible.
An embodiment of the present invention provides an implantable phrenic nerve stimulation system, which includes an implantable phrenic nerve stimulator 31 and a control device 32 thereof, as shown in fig. 3.
The implantable phrenic nerve stimulator 31 comprises a pulse generator 311, a spiral electrode 312, and a flexible lead 313. The pulse generator 311 may receive the signal transmitted by the control device 32 through a wireless communication manner, thereby setting the phrenic nerve stimulation parameter through the control device 32 to stimulate the phrenic nerve. The pulse generator 311 is placed in the subcutaneous tissue below the midline of the left clavicle of a human body, the spiral electrode 312 is wound on the phrenic nerve, and the flexible lead 313 is buried in the subcutaneous tunnel and is connected with the spiral electrode 312 and the pulse generator 311.
The control device 32 is worn on the upper chest of the person, typically on the upper edges of the lower ribs in the 7 th or 8 th intercostal space adjacent the outer edges of the rib cage. As shown in fig. 4, the control device 32 includes a physiological parameter sensor 321 for acquiring a physiological parameter of the wearer in real time, which may specifically include at least one of a heart rate sensor, a blood oxygen (saturation) sensor, and a respiration sensor.
The control device 32 also includes a diaphragm muscle electrical sensor 322, a processor 323, and a communication module 324. The monitoring probe of the blood oxygen (saturation) sensor and the electromyogram electrode plate of the diaphragm electromyogram sensor 322 are both positioned on the contact surface of the control device 32 and the human body.
The processor 323 is configured to determine whether the physiological parameter reaches a first threshold in real time, start the phrenic muscle electromyographic sensor 322 to acquire electromyographic information when the physiological parameter reaches the first threshold, determine a phrenic nerve state according to the electromyographic information, and control the implanted phrenic nerve stimulator 31 to perform a corresponding stimulation action through the communication module 324. To conserve power, the diaphragm muscle electromyography sensor 322 and the communication module 324 may be left inactive at all times, and may be activated only when the processor 323 needs to perform the corresponding action. For the method executed by the processor 323, reference may be made to the corresponding embodiment of fig. 1, which is not described herein again.
According to the control device and the system provided by the embodiment of the invention, the physiological parameters of the patient are obtained when the phrenic nerve of the patient is stimulated, whether the current physiological state of the patient is abnormal is determined by judging whether the physiological parameters reach the threshold value, then the myoelectric information of the diaphragm muscle of the patient is obtained when the physiological state is abnormal, the phrenic nerve state is determined through the information, and then the stimulator 31 is controlled to execute the stimulation action suitable for the current phrenic nerve state, so that the self-adaptive regulation of the stimulation action of equipment is realized when the vital signs of the patient are changed, the participation of professionals is not needed, and the control device and the system have strong convenience. In addition, compare in current outer hanging phrenic nerve stimulator 31, this device does not need bulky radio frequency transmitter, makes things convenient for patient's life.
In a preferred embodiment, the phrenic nerve state determined by the processor 323 includes at least a fatigue state and a non-fatigue state; the stimulation action corresponding to the fatigue state is to change the stimulation part, and the stimulation action corresponding to the non-fatigue state is to adjust the stimulation parameter according to the physiological parameter.
The implanted phrenic nerve stimulator 31 is provided with two groups of spiral electrodes 312, which are respectively used for stimulating phrenic nerves on two sides of a human body, only one group of the spiral electrodes outputs stimulation signals at the same time, and the other group of the spiral electrodes is switched to output the stimulation signals when the stimulation position is changed. The normal operation mode of the phrenic nerve stimulator 31 is unilateral stimulation, and when diaphragmatic muscle fatigue is detected, the contralateral stimulation can be adjusted, so that phrenic nerve injury/stimulation is reduced.
Further, the stimulation parameters include at least a stimulation frequency, and further include a pulse width, a stimulation frequency, a stimulation period, and the like, which are set by the processor 323 according to physiological parameters such as heart rate, blood oxygen, respiration, and the like.
In a preferred embodiment, the processor 323 is further configured to determine whether the physiological parameter reaches a second threshold, and when the physiological parameter reaches the second threshold, perform an alarm action via the communication module. For the relationship between the first threshold and the second threshold and the logic sequence of the processor 323 executing the control operation, reference may be made to fig. 2 and its corresponding embodiment, which are not described herein again. According to the preferred scheme, the safety of the patient can be ensured to the greatest extent under the condition of simulating the respiratory physiology, the patient can see a doctor in time conveniently, and hidden dangers can be found as early as possible.
In an optional embodiment, the control device 32 further includes a display module, configured to display contents such as blood oxygen saturation, myoelectric graph, phrenic nerve stimulation location, stimulation parameters, and pulse generator power, and also configured to perform an alarm action, such as displaying alarm information, so that the patient can clearly know the operation state of the stimulation system and the physiological state of the patient, and the effect of improving the safety of the patient can also be achieved.
As will be appreciated by one skilled in the art, embodiments of the present invention may be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, and the like) having computer-usable program code embodied therein.
The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flow diagrams and/or block diagrams, and combinations of flows and/or blocks in the flow diagrams and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.
These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.
It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.
Claims (10)
1. A method of controlling a phrenic nerve stimulator, comprising:
acquiring a physiological parameter;
judging whether the physiological parameter reaches a first threshold value;
acquiring myoelectric information when the physiological parameter reaches a first threshold value;
and determining the phrenic nerve state according to the myoelectric information and executing corresponding stimulation actions.
2. The method according to claim 1, wherein the phrenic nerve stimulator comprises two groups of stimulation electrodes, which are respectively used for stimulating phrenic nerves on two sides of a human body, and only one group of the stimulation electrodes outputs stimulation signals at the same time; the phrenic nerve states include at least a tired state and a non-tired state;
the stimulation action corresponding to the fatigue state is to switch another group of stimulation electrodes to output stimulation signals;
the stimulation action corresponding to the non-fatigue state is to adjust stimulation parameters according to physiological parameters, wherein the stimulation parameters comprise stimulation frequency.
3. The method of claim 1, further comprising:
judging whether the physiological parameter reaches a second threshold value;
when the physiological parameter reaches a second threshold value, an alarm action is executed.
4. The method of any one of claims 1-3, wherein the physiological parameter comprises at least one of heart rate, blood oxygen saturation, respiratory parameter.
5. A control device for a phrenic nerve stimulator, adapted to be deployed on a body surface, the device comprising:
the physiological parameter sensor is used for acquiring the physiological parameters of the wearer in real time; the diaphragm myoelectricity sensor, the processor and the communication module are connected with the external power supply; the processor is used for judging whether the physiological parameter reaches a first threshold value in real time, starting the diaphragm myoelectric sensor to collect myoelectric information when the physiological parameter reaches the first threshold value, determining the state of the phrenic nerve according to the myoelectric information, and controlling the implanted type phrenic nerve stimulator to execute corresponding stimulation actions through the communication module.
6. The apparatus of claim 5, wherein the phrenic nerve states include at least a tired state and a non-tired state;
the stimulation action corresponding to the fatigue state is to switch another group of stimulation electrodes of the phrenic nerve stimulator to output stimulation signals;
the stimulation action corresponding to the non-fatigue state is to adjust stimulation parameters according to physiological parameters, wherein the stimulation parameters comprise stimulation frequency.
7. The device of claim 5, wherein the processor is further configured to determine whether the physiological parameter reaches a second threshold, and when the physiological parameter reaches the second threshold, perform an alarm action via the communication module.
8. The device of any one of claims 5-7, wherein the physiological parameter sensor comprises at least one of a heart rate sensor, a blood oxygen saturation sensor, a respiration sensor.
9. An implantable phrenic nerve stimulation system, comprising: the control device of any one of claims 5-7, and an implantable phrenic nerve stimulator.
10. The system of claim 9, wherein the implantable phrenic nerve stimulator comprises two sets of stimulation electrodes for stimulating phrenic nerves on two sides of a human body, and only one of the sets of stimulation electrodes outputs a stimulation signal at a time.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116440408A (en) * | 2023-03-17 | 2023-07-18 | 上海杉翎医疗科技有限公司 | Implantable stimulation systems, methods, implantable devices, and storage media |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908146A (en) * | 2011-08-04 | 2013-02-06 | 罗远明 | Method for positioning diaphragmatic function detection tube by stimulating phrenic nerve |
| CN105873635A (en) * | 2013-10-25 | 2016-08-17 | 美敦力公司 | Device for automated phrenic nerve stimulation and pacing capture threshold test |
| US20160287877A1 (en) * | 2015-04-02 | 2016-10-06 | The Florida International University Board Of Trustees | System and method for neuromorphic controlled adaptive pacing of respiratory muscles and nerves |
| CN106422060A (en) * | 2016-10-21 | 2017-02-22 | 上海海神医疗电子仪器有限公司 | Dual-mode dual-control diaphragm stimulation mechanical ventilation assist device |
-
2019
- 2019-12-31 CN CN201911421209.4A patent/CN111068178A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908146A (en) * | 2011-08-04 | 2013-02-06 | 罗远明 | Method for positioning diaphragmatic function detection tube by stimulating phrenic nerve |
| CN105873635A (en) * | 2013-10-25 | 2016-08-17 | 美敦力公司 | Device for automated phrenic nerve stimulation and pacing capture threshold test |
| US20160287877A1 (en) * | 2015-04-02 | 2016-10-06 | The Florida International University Board Of Trustees | System and method for neuromorphic controlled adaptive pacing of respiratory muscles and nerves |
| CN106422060A (en) * | 2016-10-21 | 2017-02-22 | 上海海神医疗电子仪器有限公司 | Dual-mode dual-control diaphragm stimulation mechanical ventilation assist device |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116440408A (en) * | 2023-03-17 | 2023-07-18 | 上海杉翎医疗科技有限公司 | Implantable stimulation systems, methods, implantable devices, and storage media |
| CN116440408B (en) * | 2023-03-17 | 2024-01-09 | 上海杉翎医疗科技有限公司 | Implantable stimulation systems, methods, implantable devices, and storage media |
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