CN106943119A - One kind anesthesia and depth of consciousness monitoring system - Google Patents

One kind anesthesia and depth of consciousness monitoring system Download PDF

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Publication number
CN106943119A
CN106943119A CN201710139673.9A CN201710139673A CN106943119A CN 106943119 A CN106943119 A CN 106943119A CN 201710139673 A CN201710139673 A CN 201710139673A CN 106943119 A CN106943119 A CN 106943119A
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China
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key
information
sensor node
sensor
data
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倪诚
刘伟平
王军
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Peking University Third Hospital
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Peking University Third Hospital
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Priority to CN201710139673.9A priority Critical patent/CN106943119A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4821Determining level or depth of anaesthesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048Detecting, measuring or recording by applying mechanical forces or stimuli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0816Measuring devices for examining respiratory frequency
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836Measuring rate of CO2 production
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/45For evaluating or diagnosing the musculoskeletal system or teeth
    • A61B5/4519Muscles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L67/00Network arrangements or protocols for supporting network services or applications
    • H04L67/01Protocols
    • H04L67/10Protocols in which an application is distributed across nodes in the network
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L67/00Network arrangements or protocols for supporting network services or applications
    • H04L67/01Protocols
    • H04L67/10Protocols in which an application is distributed across nodes in the network
    • H04L67/1095Replication or mirroring of data, e.g. scheduling or transport for data synchronisation between network nodes
    • HELECTRICITY
    • H04ELECTRIC COMMUNICATION TECHNIQUE
    • H04LTRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHIC COMMUNICATION
    • H04L67/00Network arrangements or protocols for supporting network services or applications
    • H04L67/01Protocols
    • H04L67/12Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks

Abstract

The present invention relates to one kind anesthesia and depth of consciousness monitoring system, including monitoring sensor, analgesia/noxious stimulation index sensor, monitor for muscle relaxation wired connection with heart rate sensor, blood pressure sensor, breathing gas monitoring sensor, brain wave respectively, for the single-chip microcomputer analyzed monitoring signals and handled;For the data analysis module analyzed Monitoring Data;For the data processing module that Monitoring Data is further processed;Wave filter for eliminating jamming incoherent signal;For the operating display for being shown and being operated to monitoring signals;Radio frequency transceiving module for receiving and sending wireless network signal;With radio frequency transceiving module by GPRS wireless network wireless connections, for carrying out data transmission the Cloud Server with exchanging.The anesthesia and the monitoring of depth of consciousness monitoring system are comprehensive, and precisely, storage is safe for data analysis.

Description

One kind anesthesia and depth of consciousness monitoring system
Technical field
The invention belongs to technical field of medical equipment, more particularly to a kind of anesthesia and depth of consciousness monitoring system.
Background technology
The effect anaesthetized in surgical operation is particularly important, and rational anesthesia can be carried out in the case of patient's analgesia Operative treatment, makes patient from pain, while facilitating doctor's normal work.But anesthesia is improper, can not only eliminate patient's Pain, can also bring it is a series of other the problem of.Anesthesia is too deep, damages the nervous function of patient, and may leave nerve Sequelae even life-threatening;Anaesthetized shallow, then can not suppress noxious stimulation, and made Principle of Pain uncomfortable or instinct body is dynamic causes Operation is difficult to or occurred unexpected, it is also possible to cause intraoperative diagnosis, and causing patient to retain has memory in operation, so as to draw Play serious spirit or sleep-disorder.
With the use in conjunction of the medicaments such as new muscle relaxant and analgestic, the depth of anesthesia of general anesthesia, state of consciousness are normal It is blanked or is difficult to, judges and control the problem of suitable depth of anesthesia turns into clinical in the urgent need to address, therefore go out Some existing anesthesia and depth of consciousness monitoring device, but also have the following disadvantages:One is that monitoring means is disperseed, relatively independent, is led Cause data syn-chronization poor, it is impossible to the data dependence of reflecting point time, also can not integrally reflect the depth of anesthesia and consciousness of patient State;Two are disturbed by extraneous and internal power element, cause monitoring parameter inaccurate, the standard that influence depth of anesthesia judges True property;Three be that Monitoring Data is stored in locally, causes the possibility of loss of data big, the data during influence patient performs the operation again are sharp It is worth with coherent reference, causes operating efficiency to substantially reduce.
The content of the invention
The present invention for solve it is existing monitoring not precisely, be easily interfered with the unsafe technical problem of data storage and A kind of anesthesia and depth of consciousness monitoring system are provided.
The present invention is adopted the technical scheme that to solve technical problem present in known technology:
The anesthesia and depth of consciousness monitoring system include:
For the heart rate sensor being monitored to human heart rate;
For the blood pressure sensor being monitored to human blood-pressure;
For exhaling for being monitored to human body respiration frequency, fraction of inspired oxygen, end-expiratory carbon dioxide, inhalation anesthesia gas Inhale gas monitoring sensors;
Brain wave for being monitored to human body electroencephalogram's ripple monitors sensor;
For stimulating the analgesia/noxious stimulation index sensor being monitored to human body pain;
For the monitor for muscle relaxation being monitored to skeleton muscular relaxation degree;
Respectively with heart rate sensor, blood pressure sensor, breathing gas monitoring sensor, brain wave monitoring sensor, analgesia/ Noxious stimulation index sensor, monitor for muscle relaxation wired connection, for the single-chip microcomputer analyzed monitoring signals and handled;
With single-chip microcomputer by input module wired connection, the input keyboard for inputting patient basis;
With single-chip microcomputer wired connection, for the memory preserved to Monitoring Data;
With single-chip microcomputer wired connection, RAM memory and MRAM for being compared, sampling and inquiring about to Monitoring Data are deposited Reservoir;
With single-chip microcomputer wired connection, the power module for providing power supply;
With single-chip microcomputer wired connection, for the data analysis module analyzed Monitoring Data;
With data analysis module wired connection, for the data processing module that Monitoring Data is further processed;
With single-chip microcomputer wired connection, for the timing module recorded to the time;
With single-chip microcomputer wired connection, the wave filter for eliminating jamming incoherent signal;
With single-chip microcomputer wired connection, for data to be carried out into derived data export module;
With single-chip microcomputer wired connection, for the operating display for being shown and being operated to monitoring signals;
With single-chip microcomputer wired connection, the radio frequency transceiving module for receiving and sending wireless network signal;
With radio frequency transceiving module by GPRS wireless network wireless connections, for carrying out data transmission the cloud with exchanging Server.
Further, the operating display is specially the capacitive touch screen of multi-point touch.
Further, sound broadcasting device is installed on the operating display, sound broadcasting device passes through data wire and list Piece machine is connected.
Further, printing equipment is installed, printing equipment passes through data wire and single-chip microcomputer phase on the operating display Connection.
Further, multiple indicator lamps are installed on the operating display, indicator lamp is connected by data wire with single-chip microcomputer Connect.
Further, the single-chip microcomputer is provided with data compression unit, the data compression method of the data compression unit Step is:
Step 1: in coding, first according to E1n+1=E1n+dn+1Formula calculates E1 values, further according to WithFormula calculates regression criterion, when calculating this two step, is required to carry out result out-of-limit judgement, Judge E1 it is whether out-of-limit be in order to avoid its exceed the sensing data bus upper limit and cause overflow;Judging whether residual error is out-of-limit is In order to realize piecewise fitting;
Step 2: after the regression criterion of one section of input data has all been calculated, constructing { dn,E1n,DFR3,DFR4,… DFRnShown in packet, entropy code is carried out to it by S-Huffman coding methods, then sent, receiving terminal decoding When, first receive one group of data is decoded, { d is restoredn,E1n,DFR3,DFR4,…DFRnPacket shown in formula, then According toFormula calculates and restores all original numbers According to.
Further, the radio frequency transceiving module is provided with secure accessing unit, the safety of the secure accessing unit The method of access sets two kinds of interactive modes:Unicast mode and multicast pattern, unicast mode and multicast pattern are respectively equipped with network Telegon, which is initiated to shake hands, initiate two kinds of initiation modes of shaking hands with sensor node, and network coordinator and sensor node are strengthened Type 4-Way Handshake, obtain newest pair temporal key, for information encryption and certification;Unicast mode is no wire body Single sensor node access network telegon in the net of domain;Multicast pattern is multiple sensor node access networks in wireless body area network Network telegon, during realizing that the measurement index of some or some sensor nodes exceedes corresponding index limitation, respective sensor section Point actively initiates handshake procedure;During remote accessing, using multi-hop mode, and using between sensor node and network coordinator Distance threshold value, control single-hop and multi-hop mode between switching.
Further, the secure accessing method handshake procedure send all Information encapsulations in 802.15.6 frames, by Frame identification distinguishes the information sent in handshake procedure, network coordinator and sensor node shared key pairwise master key, net Network telegon possesses trusted sensors address of node maintenance key list { k1,k2...kN, criteria thresholds list { w1,w2… wNAnd distance threshold list { d1,d2...dN};Sensor node possesses the key k of oneselfiThree letters of cryptographic handshake process Breath, criteria thresholds value wi, range gate limitation di, key kiIt is that generation is combined by the address ID of pairwise master key and sensor node , following network coordinator and sensor node carry out enhanced 4-Way Handshake, obtain newest paired interim close Key, for later information encryption and certification;
Unicast mode is specifically included:Actively initiate mode and passive initiation mode;Unicast mode is list in wireless body area network Individual sensor node access network telegon.
Further, it is described actively to initiate mode, it is that network coordinator initiates to shake hands that to implement step as follows:
Step one, network coordinator is sent by key kAThe information Msg1 of encryption gives sensor node A, the Msg1 to include Random number N once_BNC for producing pair temporal key, and sensor node identity ID_A;
Step 2, the random number that BN_A is generated is received after Msg1, verifies identity ID_A;If being proved to be successful, BN_ is generated The random number of A generations, and key k will be passed throughAThe information Msg2 of encryption is sent to network coordinator, otherwise abandons the information;
Step 3, network coordinator is received after Msg2, the random number of checking BNC generations;If being proved to be successful, PRF is used Function combination generating random number simultaneously loads pair temporal key, and key k is then used under AES-CBC-MAC patternsACalculate The message integrity authentication code KMAC of { random number of BN_A generations, ID_A }, and it is sent to sensor section using KMAC as Msg3 Point A, otherwise abandons the information;
Step 4, sensor node A is received after Msg3, and the key k of oneself is used under AES-CBC-MAC patternsARoot KMAC' is calculated according to corresponding information, the KMAC received the and KMAC' that calculates is compared, if unanimously, sensor section Point A is with PRF function combination generating random numbers and loads pair temporal key, and follow-on 4-Way Handshake are completed, otherwise Abandon the information;
Certain sensor node index exceedes threshold value wiWhen, mode is passively initiated, is that respective sensor node initiates to shake hands Implement step as follows:
Step one, sensor node A is sent by key kAThe information Msg1 of encryption is to network coordinator, and Msg1 includes Random number N once_BNC for producing pair temporal key, and sensor node identity ID_A;
Step 2, network coordinator is received after Msg1, checking identity ID_A;If being proved to be successful, random number is generated Nonce_BNC, and key k will be passed throughAThe information Msg2 of encryption is sent to sensor node A, otherwise abandons the information;
Step 3, sensor node A is received after Msg2, the random number N once_A of verificating sensor node A generations;If It is proved to be successful, then with PRF function combination generating random numbers and loads pair temporal key, then under AES-CBC-MAC patterns Use key kACalculate BN_A generation random number, ID_A } message integrity authentication code KMAC, and using KMAC as Msg3 is sent to network coordinator, otherwise abandons the information;
Step 4, network coordinator is received after Msg3, and key k is used under AES-CBC-MAC patternsAAccording to corresponding letter Breath calculates KMAC', and the KMAC received the and KMAC' that calculates is compared, if unanimously, network coordinator PRF Function combination generating random number simultaneously loads pair temporal key, and follow-on 4-Way Handshake are completed, and otherwise abandon the letter Breath.
Further, the multicast pattern includes:Actively initiate mode and passive initiation pattern;Multicast pattern is wireless body area Multiple sensor node access network telegons in net;
Mode is actively initiated, is that network coordinator initiates to shake hands that to implement step as follows:
Step one, network coordinator multicast passes through key kiThe information Msg1 of encryption, starts modified 4-Way Handshake;
Step 2, waits i-th of sensor node to be accessed to receive multicast information Msg1, according to the prefix for obtaining information Corresponding key k is found in the cipher key list of maintenance in addressi, so as to obtain the random number and ID_i of BNC generations, verify identity ID_i, if being proved to be successful, generates random number N once_i, and will pass through key kiThe information Msg2 of encryption is sent to network association Device is adjusted, the information is otherwise abandoned;
Step 3, network coordinator receives Msg2, and the random number of checking BNC generations, if being proved to be successful, uses PRF functions With reference to generating random number and load pair temporal key PTK_i, key k is then used under AES-CBC-MAC patternsiCalculate The message integrity authentication code KMACi of { Nonce_i, ID_i }, and sensor node BN_i is sent to using KMACi as Msg3, Otherwise the information is abandoned;
Step 4, i-th of sensor node BN_i is received after Msg3, and oneself is used under AES-CBC-MAC patterns Key kiKMACi' is calculated according to corresponding information, the KMACi received the and KMACi' that calculates is compared, if one Cause, then sensor node BN_i is with PRF function combination generating random numbers and loads pair temporal key PTK_i, follow-on 4- Way Handshake are completed, and otherwise abandon the information;
Under multicast pattern it is passive initiate mode to implement step as follows:
Step one, N number of sensor node is sent by key k to network coordinatoriThe information Msg1 of encryption, starts and improves Type 4-Way Handshake;
Step 2, network coordinator receives information Msg1, according to obtaining the prefix addresses of information from the key column of maintenance Corresponding key k is found in tablei, so as to obtain Nonce_i and ID_i, and verify identity ID_i, if being proved to be successful, generate with Machine number Nonce_BNC, and key k will be passed throughiThe information Msg2 of encryption such as is sent at i-th of sensor node to be accessed, no Then abandon the information;
Step 3, sensor node _ i receives Msg2, verifies Nonce_i, if being proved to be successful, with PRF functions combine with Machine number is generated and loads pair temporal key PTK_i, and key k is then used under AES-CBC-MAC patternsiCalculate The message integrity authentication code KMACi of { Nonce_i, ID_i }, and sensor node BN_i is sent to using KMACi as Msg3, Otherwise the information is abandoned;
Step 4, network coordinator is received after Msg3, the random number of checking BNC generations, is such as proved to be successful, is then used PRF Function combination generating random number simultaneously loads pair temporal key PTK_i, and key k is then used under AES-CBC-MAC patternsiRoot KMACi' is calculated according to corresponding information, the KMACi received the and KMACi' that calculates is compared, if unanimously, network Telegon is with PRF function combination generating random numbers and loads pair temporal key PTK_i, follow-on 4-Way Handshake Complete, otherwise abandon the information.
The present invention has the advantages and positive effects of:The anesthesia and the monitoring of depth of consciousness monitoring system are comprehensive, data point Analysis is accurate, storage safety;Sensor, brain wave monitoring sensing are monitored by heart rate sensor, blood pressure sensor, breathing gas Device, analgesia/noxious stimulation index sensor, monitor for muscle relaxation are anaesthetized and depth of consciousness progress comprehensive monitoring to human body, concurrently It is sent in single-chip microcomputer, extraneous and internal jamming incoherent signal is eliminated by wave filter, it is ensured that Monitoring Data precision, during each data Between correlation it is strong, data more meet clinical practice situation, are deposited Monitoring Data by radio frequency transceiving module using single-chip microcomputer Store up in Cloud Server, it is ensured that the storage safety of data and extraction are used, pass through RAM memory, mram memory and cloud service Monitoring Data is compared device, sample inquiry and storage, facilitates doctor to judge the degree of human body anesthesia and depth of consciousness, more preferably Ground is controlled and performed the operation.
Brief description of the drawings
Fig. 1 is the theory diagram of anesthesia provided in an embodiment of the present invention and depth of consciousness monitoring system;
In figure:1st, heart rate sensor;2nd, blood pressure sensor;3rd, breathing gas monitoring sensor;4th, brain wave monitoring sensing Device;5th, analgesia/noxious stimulation index sensor;6th, monitor for muscle relaxation;7th, input module;8th, input keyboard;9th, memory; 10th, RAM memory;11st, mram memory;12nd, power module;13rd, data analysis module;14th, data processing module;15th, count When module;16th, wave filter;17th, data export module;18th, operating display;19th, radio frequency transceiving module;20th, cloud service Device;21st, sound broadcasting device;22nd, printing equipment;23rd, indicator lamp;24th, single-chip microcomputer.
Embodiment
For the content of the invention, feature and effect of the present invention can be further appreciated that, following examples are hereby enumerated, and coordinate accompanying drawing Describe in detail as follows.
The structure of the present invention is explained in detail with reference to Fig. 1.
The anesthesia and depth of consciousness monitoring system include:
For the heart rate sensor 1 being monitored to human heart rate;
For the blood pressure sensor 2 being monitored to human blood-pressure;
For exhaling for being monitored to human body respiration frequency, fraction of inspired oxygen, end-expiratory carbon dioxide, inhalation anesthesia gas Inhale gas monitoring sensors 3;
Brain wave for being monitored to human body electroencephalogram's ripple monitors sensor 4;
Analgesia/noxious stimulation the index sensor 5 monitored for pain stimulation;
For the monitor for muscle relaxation 6 being monitored to skeleton muscular relaxation degree;
Respectively with heart rate sensor 1, blood pressure sensor 2, breathing gas monitoring sensor 3, brain wave monitoring sensor 4, Analgesia/noxious stimulation index sensor 5, the wired connection of monitor for muscle relaxation 6, for what is analyzed monitoring signals and handled Single-chip microcomputer 24;
With single-chip microcomputer 24 by the wired connection of input module 7, the input keyboard 8 for inputting patient basis;
With the wired connection of single-chip microcomputer 24, for the memory 9 preserved to Monitoring Data;
With the wired connection of single-chip microcomputer 24, for the and of RAM memory 10 for being compared, sampling and inquiring about to Monitoring Data Mram memory 11;
With the wired connection of single-chip microcomputer 24, the power module 12 for providing power supply;
With the wired connection of single-chip microcomputer 24, for the data analysis module 13 analyzed Monitoring Data;
With the wired connection of data analysis module 13, for the data processing module that Monitoring Data is further processed 14;
With the wired connection of single-chip microcomputer 24, for the timing module 15 recorded to the time;
With the wired connection of single-chip microcomputer 24, the wave filter 16 for eliminating jamming incoherent signal;
With the wired connection of single-chip microcomputer 24, for data to be carried out into derived data export module 17;
With the wired connection of single-chip microcomputer 24, for the operating display 18 for being shown and being operated to monitoring signals;
With the wired connection of single-chip microcomputer 24, the radio frequency transceiving module 19 for receiving and sending wireless network signal;
With radio frequency transceiving module 19 by GPRS wireless network wireless connections, for carrying out data transmission and exchanging Cloud Server 20.
Further, the operating display 18 is specially the capacitive touch screen of multi-point touch.
Further, sound broadcasting device 21 is installed on the operating display 18, sound broadcasting device 21 passes through data Line is connected with single-chip microcomputer 24.
Further, printing equipment 22 is installed on the operating display 18, printing equipment 22 passes through data wire and list Piece machine 24 is connected.
Further, multiple indicator lamps 23 are installed on the operating display 18, indicator lamp 23 passes through data wire and monolithic Machine 24 is connected.
Further, the single-chip microcomputer is provided with data compression unit, the data compression method of the data compression unit Step is:
Step 1: in coding, first according to E1n+1=E1n+dn+1Formula calculates E1 values, further according toWithFormula calculates regression criterion, when calculating this two step, is required to To result carry out it is out-of-limit judge, judge E1 it is whether out-of-limit be in order to avoid its more than the sensing data bus upper limit and cause to overflow Go out;Judge residual error it is whether out-of-limit be to realize piecewise fitting;
Step 2: after the regression criterion of one section of input data has all been calculated, constructing { dn,E1n,DFR3,DFR4,… DFRnShown in packet, entropy code is carried out to it by S-Huffman coding methods, then sent, receiving terminal decoding When, first receive one group of data is decoded, { d is restoredn,E1n,DFR3,DFR4,…DFRnPacket shown in formula, then According toFormula calculates and restores all original numbers According to.
Further, the radio frequency transceiving module is provided with secure accessing unit, the safety of the secure accessing unit The method of access sets two kinds of interactive modes:Unicast mode and multicast pattern, unicast mode and multicast pattern are respectively equipped with network Telegon, which is initiated to shake hands, initiate two kinds of initiation modes of shaking hands with sensor node, and network coordinator and sensor node are strengthened Type 4-Way Handshake, obtain newest pair temporal key, for information encryption and certification;Unicast mode is no wire body Single sensor node access network telegon in the net of domain;Multicast pattern is multiple sensor node access networks in wireless body area network Network telegon, during realizing that the measurement index of some or some sensor nodes exceedes corresponding index limitation, respective sensor section Point actively initiates handshake procedure;During remote accessing, using multi-hop mode, and using between sensor node and network coordinator Distance threshold value, control single-hop and multi-hop mode between switching.
Further, the secure accessing method handshake procedure send all Information encapsulations in 802.15.6 frames, by Frame identification distinguishes the information sent in handshake procedure, network coordinator and sensor node shared key pairwise master key, net Network telegon possesses trusted sensors address of node maintenance key list { k1,k2...kN, criteria thresholds list { w1,w2… wNAnd distance threshold list { d1,d2...dN};Sensor node possesses the key k of oneselfiThree letters of cryptographic handshake process Breath, criteria thresholds value wi, range gate limitation di, key kiIt is that generation is combined by the address ID of pairwise master key and sensor node , following network coordinator and sensor node carry out enhanced 4-Way Handshake, obtain newest paired interim close Key, for later information encryption and certification;
Unicast mode is specifically included:Actively initiate mode and passive initiation mode;Unicast mode is list in wireless body area network Individual sensor node access network telegon.
Further, it is described actively to initiate mode, it is that network coordinator initiates to shake hands that to implement step as follows:
Step one, network coordinator is sent by key kAThe information Msg1 of encryption gives sensor node A, the Msg1 to include Random number N once_BNC for producing pair temporal key, and sensor node identity ID_A;
Step 2, the random number that BN_A is generated is received after Msg1, verifies identity ID_A;If being proved to be successful, BN_ is generated The random number of A generations, and key k will be passed throughAThe information Msg2 of encryption is sent to network coordinator, otherwise abandons the information;
Step 3, network coordinator is received after Msg2, the random number of checking BNC generations;If being proved to be successful, PRF is used Function combination generating random number simultaneously loads pair temporal key, and key k is then used under AES-CBC-MAC patternsACalculate The message integrity authentication code KMAC of { random number of BN_A generations, ID_A }, and it is sent to sensor section using KMAC as Msg3 Point A, otherwise abandons the information;
Step 4, sensor node A is received after Msg3, and the key k of oneself is used under AES-CBC-MAC patternsARoot KMAC' is calculated according to corresponding information, the KMAC received the and KMAC' that calculates is compared, if unanimously, sensor section Point A is with PRF function combination generating random numbers and loads pair temporal key, and follow-on 4-Way Handshake are completed, otherwise Abandon the information;
Certain sensor node index exceedes threshold value wiWhen, mode is passively initiated, is that respective sensor node initiates to shake hands Implement step as follows:
Step one, sensor node A is sent by key kAThe information Msg1 of encryption is to network coordinator, and Msg1 includes Random number N once_BNC for producing pair temporal key, and sensor node identity ID_A;
Step 2, network coordinator is received after Msg1, checking identity ID_A;If being proved to be successful, random number is generated Nonce_BNC, and key k will be passed throughAThe information Msg2 of encryption is sent to sensor node A, otherwise abandons the information;
Step 3, sensor node A is received after Msg2, the random number N once_A of verificating sensor node A generations;If It is proved to be successful, then with PRF function combination generating random numbers and loads pair temporal key, then under AES-CBC-MAC patterns Use key kACalculate BN_A generation random number, ID_A } message integrity authentication code KMAC, and using KMAC as Msg3 is sent to network coordinator, otherwise abandons the information;
Step 4, network coordinator is received after Msg3, and key k is used under AES-CBC-MAC patternsAAccording to corresponding letter Breath calculates KMAC', and the KMAC received the and KMAC' that calculates is compared, if unanimously, network coordinator PRF Function combination generating random number simultaneously loads pair temporal key, and follow-on 4-Way Handshake are completed, and otherwise abandon the letter Breath.
Further, the multicast pattern includes:Actively initiate mode and passive initiation pattern;Multicast pattern is wireless body area Multiple sensor node access network telegons in net;
Mode is actively initiated, is that network coordinator initiates to shake hands that to implement step as follows:
Step one, network coordinator multicast passes through key kiThe information Msg1 of encryption, starts modified 4-Way Handshake;
Step 2, waits i-th of sensor node to be accessed to receive multicast information Msg1, according to the prefix for obtaining information Corresponding key k is found in the cipher key list of maintenance in addressi, so as to obtain the random number and ID_i of BNC generations, verify identity ID_i, if being proved to be successful, generates random number N once_i, and will pass through key kiThe information Msg2 of encryption is sent to network association Device is adjusted, the information is otherwise abandoned;
Step 3, network coordinator receives Msg2, and the random number of checking BNC generations, if being proved to be successful, uses PRF functions With reference to generating random number and load pair temporal key PTK_i, key k is then used under AES-CBC-MAC patternsiCalculate The message integrity authentication code KMACi of { Nonce_i, ID_i }, and sensor node BN_i is sent to using KMACi as Msg3, Otherwise the information is abandoned;
Step 4, i-th of sensor node BN_i is received after Msg3, and oneself is used under AES-CBC-MAC patterns Key kiKMACi' is calculated according to corresponding information, the KMACi received the and KMACi' that calculates is compared, if one Cause, then sensor node BN_i is with PRF function combination generating random numbers and loads pair temporal key PTK_i, follow-on 4- Way Handshake are completed, and otherwise abandon the information;
Under multicast pattern it is passive initiate mode to implement step as follows:
Step one, N number of sensor node is sent by key k to network coordinatoriThe information Msg1 of encryption, starts and improves Type 4-Way Handshake;
Step 2, network coordinator receives information Msg1, according to obtaining the prefix addresses of information from the key column of maintenance Corresponding key k is found in tablei, so as to obtain Nonce_i and ID_i, and verify identity ID_i, if being proved to be successful, generate with Machine number Nonce_BNC, and key k will be passed throughiThe information Msg2 of encryption such as is sent at i-th of sensor node to be accessed, no Then abandon the information;
Step 3, sensor node _ i receives Msg2, verifies Nonce_i, if being proved to be successful, with PRF functions combine with Machine number is generated and loads pair temporal key PTK_i, and key k is then used under AES-CBC-MAC patternsiCalculate The message integrity authentication code KMACi of { Nonce_i, ID_i }, and sensor node BN_i is sent to using KMACi as Msg3, Otherwise the information is abandoned;
Step 4, network coordinator is received after Msg3, the random number of checking BNC generations, is such as proved to be successful, is then used PRF Function combination generating random number simultaneously loads pair temporal key PTK_i, and key k is then used under AES-CBC-MAC patternsiRoot KMACi' is calculated according to corresponding information, the KMACi received the and KMACi' that calculates is compared, if unanimously, network Telegon is with PRF function combination generating random numbers and loads pair temporal key PTK_i, follow-on 4-Way Handshake Complete, otherwise abandon the information.
The structure of the present invention is further described with reference to operation principle.
Sensor 3, brain wave are monitored by heart rate sensor 1, blood pressure sensor 2, breathing gas and monitor sensor 4, town Bitterly/noxious stimulation index sensor 5, monitor for muscle relaxation 6 are anaesthetized to human body and depth of consciousness carries out comprehensive monitoring, and are sent to In single-chip microcomputer 24, extraneous and internal jamming incoherent signal is eliminated by wave filter 16, it is ensured that Monitoring Data precision, utilize single-chip microcomputer 24 are stored Monitoring Data into Cloud Server 20 by radio frequency transceiving module 19, it is ensured that the storage safety of data and extraction Use, Monitoring Data is compared, sample, inquire about and deposited by RAM memory 10, mram memory 11 and Cloud Server 20 Storage, facilitates doctor to judge the degree of human body anesthesia and depth of consciousness, is preferably controlled and performs the operation, will using input keyboard 8 The essential information of patient is input in single-chip microcomputer 24 by input module 7, by single-chip microcomputer 24 by Monitoring Data and essential information Analyzed and processed by data analysis module 13 and data processing module 14, judge anesthesia and the depth of consciousness of patient, power supply Module 12 provides power supply, can export Monitoring Data using data export module 17, be shown by operating display 18 Come, can also be played back by sound broadcasting device 21, can also be printed and be preserved by printing equipment 22, timing module 15 are used for timing.
The above is only the preferred embodiments of the present invention, and not makees any formal limitation to the present invention, Every technical spirit according to the present invention is belonged to any simple modification made for any of the above embodiments, equivalent variations and modification In the range of technical solution of the present invention.

Claims (3)

1. one kind anesthesia and depth of consciousness monitoring system, its feature and monitoring system content include:
For the heart rate sensor being monitored to human heart rate;
For the blood pressure sensor being monitored to human blood-pressure;
For the tidal air being monitored to human body respiration frequency, fraction of inspired oxygen, end-expiratory carbon dioxide, inhalation anesthesia gas Body monitors sensor;
Brain wave for being monitored to human body electroencephalogram's ripple monitors sensor;
For stimulating the analgesia/noxious stimulation index sensor being monitored to human body pain;
For the monitor for muscle relaxation being monitored to skeleton muscular relaxation degree;
Respectively with heart rate sensor, blood pressure sensor, breathing gas monitoring sensor, brain wave monitoring sensor, analgesia/injury Sexual stimulus index sensor, monitor for muscle relaxation wired connection, for the single-chip microcomputer analyzed monitoring signals and handled;It is described The step of single-chip microcomputer is provided with data compression unit, the data compression method of the data compression unit be:
Step 1: in coding, first according to E1n+1=E1n+dn+1Formula calculates E1 values, further according to WithFormula calculates regression criterion, when calculating this two step, is required to carry out result out-of-limit judgement, Judge E1 it is whether out-of-limit be in order to avoid its exceed the sensing data bus upper limit and cause overflow;Judging whether residual error is out-of-limit is In order to realize piecewise fitting;
Step 2: after the regression criterion of one section of input data has all been calculated, constructing { dn,E1n,DFR3,DFR4,…DFRn} Shown packet, carries out entropy code to it by S-Huffman coding methods, then sends, when receiving terminal is decoded, first Receive one group of data is decoded, { d is restoredn,E1n,DFR3,DFR4,…DFRnPacket shown in formula, then basisFormula calculates and restores all initial data;
With single-chip microcomputer by input module wired connection, the input keyboard for inputting patient basis;
With single-chip microcomputer wired connection, for the memory preserved to Monitoring Data;
With single-chip microcomputer wired connection, RAM memory and MRAM for being compared, sampling and inquiring about to Monitoring Data are stored Device;
With single-chip microcomputer wired connection, the power module for providing power supply;
With single-chip microcomputer wired connection, for the data analysis module analyzed Monitoring Data;
With data analysis module wired connection, for the data processing module that Monitoring Data is further processed;
With single-chip microcomputer wired connection, for the timing module recorded to the time;
With single-chip microcomputer wired connection, the wave filter for eliminating jamming incoherent signal;
With single-chip microcomputer wired connection, for data to be carried out into derived data export module;
With single-chip microcomputer wired connection, for the operating display for being shown and being operated to monitoring signals;
With single-chip microcomputer wired connection, the radio frequency transceiving module for receiving and sending wireless network signal;It is described wirelessly to penetrate Frequency transceiver module is provided with secure accessing unit, and the method for the secure accessing of the secure accessing unit sets two kinds of interactive moulds Formula:Unicast mode and multicast pattern, unicast mode and multicast pattern are respectively equipped with network coordinator and initiate to shake hands and sensor section Point initiation is shaken hands two kinds of initiation modes, and network coordinator and sensor node carry out enhanced 4-Way Handshake, obtain most New pair temporal key, for information encryption and certification;Unicast mode is single sensor node access in wireless body area network Network coordinator;Multicast pattern is multiple sensor node access network telegons in wireless body area network, to realize heart rate, blood When pressure, monitoring of respiration parameter, brain wave, pain, skeletal muscle relaxation degree suddenly change, i.e. some or some sensor nodes When measurement index exceedes corresponding index limitation, respective sensor node actively initiates handshake procedure;During remote accessing, using many Jump mode, and using the distance between sensor node and network coordinator threshold value, between control single-hop and multi-hop mode Switching;
The multicast pattern includes:Actively initiate mode and passive initiation pattern;Multicast pattern is multiple biographies in wireless body area network Sensor node access network telegon;
Mode is actively initiated, is that network coordinator initiates to shake hands that to implement step as follows:
Step one, network coordinator multicast passes through key kiThe information Msg1 of encryption, starts modified 4-Way Handshake;
Step 2, waits i-th of sensor node to be accessed to receive multicast information Msg1, according to the prefix addresses for obtaining information Corresponding key k is found in the cipher key list of maintenancei, so as to obtain the random number and ID_i of BNC generations, checking identity ID_ I, if being proved to be successful, generates random number N once_i, and will pass through key kiThe information Msg2 of encryption is sent to the network coordination Device, otherwise abandons the information;
Step 3, network coordinator receives Msg2, and the random number of checking BNC generations, if being proved to be successful, is combined with PRF functions Generating random number simultaneously loads pair temporal key PTK_i, and key k is then used under AES-CBC-MAC patternsiCalculate The message integrity authentication code KMACi of { Nonce_i, ID_i }, and sensor node BN_i is sent to using KMACi as Msg3, Otherwise the information is abandoned;
Step 4, i-th of sensor node BN_i is received after Msg3, and the key k of oneself is used under AES-CBC-MAC patternsi KMACi' is calculated according to corresponding information, the KMACi received the and KMACi' that calculates is compared, if unanimously, passing Sensor node BN_i is with PRF function combination generating random numbers and loads pair temporal key PTK_i, follow-on 4-Way Handshake is completed, and otherwise abandons the information;
Under multicast pattern it is passive initiate mode to implement step as follows:
Step one, N number of sensor node is sent by key k to network coordinatoriThe information Msg1 of encryption, starts modified 4- Way Handshake;
Step 2, network coordinator receives information Msg1, according to obtaining the prefix addresses of information in the cipher key list of maintenance Find corresponding key ki, so as to obtain Nonce_i and ID_i, and identity ID_i is verified, if being proved to be successful, generates random number Nonce_BNC, and key k will be passed throughiThe information Msg2 of encryption such as is sent at i-th of sensor node to be accessed, otherwise loses Abandon the information;
Step 3, sensor node _ i receives Msg2, Nonce_i is verified, if being proved to be successful, with PRF function combination random numbers Generate and load pair temporal key PTK_i, key k is then used under AES-CBC-MAC patternsiCalculate Nonce_i, ID_i } message integrity authentication code KMACi, and be sent to sensor node BN_i using KMACi as Msg3, otherwise abandoning should Information;
Step 4, network coordinator is received after Msg3, the random number of checking BNC generations, is such as proved to be successful, is then used PRF functions With reference to generating random number and load pair temporal key PTK_i, key k is then used under AES-CBC-MAC patternsiAccording to phase Answer information to calculate KMACi', the KMACi received the and KMACi' that calculates is compared, if unanimously, the network coordination Device is with PRF function combination generating random numbers and loads pair temporal key PTK_i, follow-on 4-Way Handshake completions, Otherwise the information is abandoned;
With radio frequency transceiving module by GPRS wireless network wireless connections, for carrying out data transmission the cloud service with exchanging Device;
The operating display is specially the capacitive touch screen of multi-point touch;
Sound broadcasting device is installed, sound broadcasting device is connected by data wire with single-chip microcomputer on the operating display;
Printing equipment is installed, printing equipment is connected by data wire with single-chip microcomputer on the operating display;
Multiple indicator lamps are installed, indicator lamp is connected by data wire with single-chip microcomputer on the operating display.
2. anesthesia as claimed in claim 1 and depth of consciousness monitoring system, it is characterised in that the method for the secure accessing is held All Information encapsulations that hand process is sent are distinguished the information sent in handshake procedure, net by frame identification in 802.15.6 frames Network telegon and sensor node shared key pairwise master key, network coordinator possess trusted sensors address of node dimension Protect cipher key list { k1,k2...kN, criteria thresholds list { w1,w2...wNAnd distance threshold list { d1,d2...dN};Sensing Device node possesses the key k of oneselfiThree information of cryptographic handshake process, criteria thresholds value wi, range gate limitation di, key ki It is that generation is combined by the address ID of pairwise master key and sensor node, following network coordinator and sensor node are carried out Enhanced 4-WayHandshake, obtains newest pair temporal key, for later information encryption and certification;
Unicast mode is specifically included:Actively initiate mode and passive initiation mode;Unicast mode is single biography in wireless body area network Sensor node access network telegon.
3. anesthesia as claimed in claim 2 and depth of consciousness monitoring system, it is characterised in that described actively to initiate mode, are Network coordinator initiates to shake hands, and to implement step as follows:
Step one, network coordinator is sent by key kAThe information Msg1 of encryption to sensor node A, the Msg1 to include being used for Produce the random number N once_BNC of pair temporal key, and sensor node identity ID_A;
Step 2, the random number that BN_A is generated is received after Msg1, verifies identity ID_A;If being proved to be successful, generation BN_A lifes Into random number, and key k will be passed throughAThe information Msg2 of encryption is sent to network coordinator, otherwise abandons the information;
Step 3, network coordinator is received after Msg2, the random number of checking BNC generations;If being proved to be successful, PRF functions are used With reference to generating random number and load pair temporal key, key k is then used under AES-CBC-MAC patternsACalculate { BN_A The random number of generation, ID_A } message integrity authentication code KMAC, and be sent to sensor node A using KMAC as Msg3, it is no Then abandon the information;
Step 4, sensor node A is received after Msg3, and the key k of oneself is used under AES-CBC-MAC patternsAAccording to corresponding Information calculates KMAC', and the KMAC received the and KMAC' that calculates is compared, if unanimously, sensor node A is used PRF function combination generating random numbers simultaneously load pair temporal key, and follow-on 4-Way Handshake are completed, and are otherwise abandoned The information;
Certain sensor node index exceedes threshold value wiWhen, mode is passively initiated, is that respective sensor node initiates specific reality of shaking hands Existing step is as follows:
Step one, sensor node A is sent by key kAThe information Msg1 of encryption is to network coordinator, and Msg1 includes being used for Produce the random number N once_BNC of pair temporal key, and sensor node identity ID_A;
Step 2, network coordinator is received after Msg1, checking identity ID_A;If being proved to be successful, random number N once_ is generated BNC, and key k will be passed throughAThe information Msg2 of encryption is sent to sensor node A, otherwise abandons the information;
Step 3, sensor node A is received after Msg2, the random number N once_A of verificating sensor node A generations;If checking Success, then with PRF function combination generating random numbers and load pair temporal key, then used under AES-CBC-MAC patterns Key kAThe message integrity authentication code KMAC of { random number of BN_A generations, ID_A } is calculated, and is sent out KMAC as Msg3 Network coordinator is given, the information is otherwise abandoned;
Step 4, network coordinator is received after Msg3, and key k is used under AES-CBC-MAC patternsAAccording to corresponding information meter KMAC' is calculated, the KMAC received the and KMAC' that calculates is compared, if unanimously, network coordinator PRF functions With reference to generating random number and load pair temporal key, follow-on 4-Way Handshake are completed, and otherwise abandon the information.
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