CN106924874A - The system that a kind of constant pressure electric pulse imports AIDS nucleic acid vaccine - Google Patents
The system that a kind of constant pressure electric pulse imports AIDS nucleic acid vaccine Download PDFInfo
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- CN106924874A CN106924874A CN201511027117.XA CN201511027117A CN106924874A CN 106924874 A CN106924874 A CN 106924874A CN 201511027117 A CN201511027117 A CN 201511027117A CN 106924874 A CN106924874 A CN 106924874A
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- Prior art keywords
- pulse
- aids
- nucleic acid
- acid vaccine
- electric pulse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Electrotherapy Devices (AREA)
Abstract
The invention discloses the system that a kind of constant pressure electric pulse imports AIDS nucleic acid vaccine, prevention and the nucleic acid vaccine for the treatment of AIDS can be made to enter cell, so that improving it imports internal efficiency, strengthen therapeutic effect.Its technical scheme is：AIDS nucleic acid vaccine is injected first with injection device, sending low-frequency electric pulse by electric pulse gatherer again stimulates the target tissues such as the muscle of human body, make prevention and the nucleic acid vaccine molecule importing for the treatment of AIDS intracellular, enhancing therapeutic effect, and by waveform parameter and the importing effect of the design adjustment AIDS vaccine of load electrode, reach effect that is efficient, preventing to low amounts and treat AIDS.
Description
Technical field
To be prevented using electroporation technology and treatment AIDS the present invention relates to vaccine import system, more particularly to one kind
The system that the nucleic acid vaccine of disease imports target tissue.
Background technology
Early in 1981, the first in the world example aids patient is found that, the continuous variation of virus, gene have various
Property, the vaccine development Vaccine Development for causing AIDS with high costs is affected with application.Improve efficient, drop
Low cost turns into main focus.Vaccine point prevention vaccine and treatment vaccine, the effect for preventing vaccine is to prevent sense
Catch an illness poison, and the effect for the treatment of vaccine, then it is to lure that human immune system plays damage of the resistance virus to human body into,
Or enhancing immune system is directed to infect the crowd of virus to the resistivity of virus.From 1985
Before and after year to nineteen ninety, the quantity of HIV-positive is in the slow growth stage, to after the nineties in 20th century
Phase, the quantity of HIV-positive enters the stage of rapid growth.At present, the quantity of HIV infection has been presented
Rapidly increase, logarithm increases period.Not only to prevent, and to face the treatment of more HIV persons.Chinese mugwort
Grow the forfeiture that the topmost problem of patient is immunologic function, then as long as find one kind can effectively trigger and extensive
The method of multiple its own immunocompetence, the state of an illness should be controlled.
But the importing efficiency of current anti-AIDS nucleic acid vaccine is low, objectively have impact on the performance of its effect.Therefore
Give full play to the function of nucleic acid vaccine, it is necessary to improve it and import the work(that efficiency improves its immune performance to reach
Effect.
The content of the invention
The brief overview of one or more aspects given below is providing to the basic comprehension in terms of these.This general introduction
The extensive overview of the not all aspect for contemplating, and be both not intended to identify the key of all aspects or determine
Qualitative key element is also non-to be attempted to define the scope in terms of any or all.Its unique purpose be will in simplified form to
Some concepts for going out one or more aspects think the sequence of more detailed description given later.
It is an object of the invention to solve the above problems, there is provided a kind of constant pressure electric pulse imports AIDS nucleic acid epidemic disease
The system of seedling, can make prevention and the nucleic acid vaccine for the treatment of AIDS enter cell, so that it is internal to improve its importing
Efficiency, strengthens therapeutic effect.
The technical scheme is that：AIDS nucleic acid vaccine is imported present invention is disclosed a kind of constant pressure electric pulse
System, target tissue is imported by AIDS nucleic acid vaccine by low-frequency electric pulse, and system includes：
Injection device, contains AIDS nucleic acid vaccine；
Electric pulse gatherer, it is further included：
Pulse sets and implements module, receives the electric pulse parameter of user input；
Power module, produces DC signal；
Microcontroller, is set with pulse respectively and implementation module, power module are electrically connected, and is received pulse and is set
The electric pulse parameter of module output is put and implements, according to electric pulse parameter output control signal；
Pulse generation module, and pulse sets and implements module electrical connection, according to control signal by direct current
Into output electric pulse signal after constant pressure electric impulse signal, the waveform of the electric impulse signal of output is symmetrical to signal transacting
Unidirectional continuous impulse square wave is triggered, pulse frequency is 1 to 50Hz, and pulse width is 1ms to 150ms, pulse
Number is 1 to 20；And
Load, and the electrical connection of pulse generation module, receive the electric impulse signal of pulse generation module output.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, and electric pulse is led
Entering device also includes：
Information feedback module, respectively with microcontroller, load electrical connection, the portion that detection electric impulse signal is imported
The electric current of position simultaneously feeds back to microcontroller.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, and electric pulse is led
Entering device also includes：
Memory module, and microcontroller electrical connection, for storing channel genes record.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, and electric pulse is led
Entering device also includes：
Information transmission modular, and microcontroller electrical connection, the information exchange for realizing the machine and host computer.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, pulse generation
The electric impulse signal of module output is that 60V constant pressures, pulse width are that 50ms, frequency are that 1Hz, pulse number are
The unidirectional continuous impulse square wave of 6.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, pulse generation
The electric impulse signal of module output is that 90V constant pressures, pulse width are that 50ms, frequency are that 1Hz, pulse number are
The unidirectional continuous impulse square wave of 6.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, pulse generation
Module output electric impulse signal be 108V constant pressures, pulse width be 30ms, frequency be 1Hz, pulse number
It is the unidirectional continuous impulse square wave of 6.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, and load is milli
Pin electrode, filiform needle electrode is formed by connecting by electrode tip and electrode handle, and the plug of wherein electrode tip is inserted in electrode handle
Groove in.
Constant pressure electric pulse of the invention imports an embodiment of the system of AIDS nucleic acid vaccine, on electrode tip
It is provided with 2 electrodes and electrode spacing is 5mm；Or electrode tip be provided with square arrangement 4 electrodes and
Electrode spacing is 5mm；Or electrode tip is provided with and is in 4 electrodes and electrode spacing of diamond arrangement
6mm。
Present invention contrast prior art has following beneficial effect：The present invention injects AIDS first with injection device
Nucleic acid vaccine, then the target tissues such as the muscle of low-frequency electric pulse stimulation human body are sent by electric pulse gatherer, make
Prevention and the nucleic acid vaccine molecule importing for the treatment of AIDS are intracellular, enhance therapeutic effect, and by waveform
The importing effect of the design adjustment AIDS vaccine of parameter and load electrode, reaches efficiently, prevent and control to low amounts
Treat effect of AIDS.
Brief description of the drawings
Fig. 1 shows that constant pressure electric pulse of the invention imports the preferred embodiment of the system of AIDS nucleic acid vaccine
Schematic diagram.
Fig. 2A, 2B show the schematic diagram of the power module in embodiment illustrated in fig. 1.
Fig. 3 A, 3B show the electrical schematic diagram of electric pulse gatherer of the invention.
Fig. 4 shows the control principle drawing of electric pulse gatherer.
Fig. 5 A to 5C show the structural representation of load.
Specific embodiment
After the detailed description for reading embodiment of the disclosure in conjunction with the following drawings, this hair is better understood when
Bright features described above and advantage.In the accompanying drawings, each component is not necessarily drawn to scale, and with similar
The component of correlation properties or feature may have same or like reference.
Fig. 1 shows a principle for preferred embodiment of the system of importing AIDS nucleic acid vaccine of the invention,
Refer to Fig. 1.The system of the present embodiment includes electric pulse gatherer 10 and the two parts of injection device 20.Its
Middle injection device 2 can be a Syringe injector.Electric pulse gatherer 10 includes：Power module 100,
Pulse sets and implements module 101, pulse generation module 102, microcontroller 106 and load 107.Preferably,
Electric pulse gatherer 10 also includes：Information feedback module 103, memory module 104 and information transmission modular
105。
Annexation between these modules is as shown in figure 1, the output end connection microcontroller of power module 100
106, pulse sets and implements the input connection microcontroller 106 of module 101, its output end connection pulse hair
Raw module 102.Information transmission modular 105 and memory module 104 set up two-way number with microcontroller 106
According to connection.The output end connection load 107 of pulse generating module 102, the output end link information of load 107
Feedback module 103.
Injection device 20 contains anti-AIDS vaccine.Generally first by injection device 20 inject anti-AIDS vaccine to
Human body target site, is advanced centered on injection point.
At the DC signal that pulse generating module 102 provides power module according to the control signal of microcontroller
Electric impulse signal is output as after managing into constant pressure electric impulse signal, the waveform of the electric impulse signal of output is symmetrical trigger
Unidirectional continuous impulse square wave, pulse frequency is 1 to 50Hz, and pulse width is 1ms to 150ms, pulse number
It is 1 to 20.In specific implementation, this electric impulse signal can be that 60V constant pressures, a pulse are wide
Degree 50ms, frequency 1Hz, the unidirectional continuous impulse square wave that pulse number is 6；It can also be a 90V perseverance
Pressure, pulse width 50ms, frequency 1Hz, pulse number are the unidirectional continuous impulse square wave of 6；Can also be
One 108V constant pressures, pulse width 30ms, frequency 1Hz, the unidirectional continuous impulse side that pulse number is 6
Ripple.
The electric current of the detection electric impulse signal imported parts of information feedback module 103 simultaneously feeds back via microcontroller 106
Module 101 is set and implemented to pulse.Pulse setting and implementation module 101 decide whether defeated according to feedback information
Go out pulse.
Memory module 104 is used to store channel genes record.And information transmission modular 105 be used for realize the machine and
The information exchange of host computer.
Power module 100 is used to provide the energy of electric pulse generation.Power module 100 provides suitable pulse electricity
Pressure and waveform etc. import parameter.Fig. 2A, 2B show the principle of power module, and Fig. 2A shows direct current
A kind of implementation method in source, battery pack is divided into 5-500V and (DC5V, DC3.3V) via voltage processing module
This is used to drive electric impulse signal all the way for two-way, wherein 5-500V, and (DC5V, DC3.3V) this all the way
For system control.Fig. 2 B show a kind of implementation method of AC power, 220V alternating currents by voltage every
After, power filter, the first via forms the driving voltage of 5-500V, the second tunnel after being processed through overvoltage
The system control voltage that 5V and 3.3V is formed after being processed with voltage is processed by transformation.Further refer to figure
3A, corresponding to Fig. 2A, the driving voltage of 5-500V acts on load, and the information of load is anti-via information again
Feedback module 103 feeds back to the systems control division point of microcontroller 106.Fig. 3 B are referred to, corresponding to Fig. 2 B,
Driving voltage acts on load, and the information at load feeds back to microcontroller 106 via information feedback module 103 again
Systems control division point.
Microcontroller 106 is used to control the running of modules.The running to modules of microcontroller 106
Control is as shown in figure 4, system voltage control module (5V, 3.3V) provides system voltage to microcontroller 106.
The control of microcontroller 106 display, keyboard, clock, data storage management.Microcontroller 106 passes through voltage
Control module controls the suitable voltage (5-500V) of pulsed drive, and load is acted on by pulsed drive module.Letter
Breath feedback module 103 implements resistance detection in load, and feedback information is back into microcontroller 106.
The operation principle of system of the invention is：It is suitable to be produced by Technology designs such as booster circuit and reduction voltage circuits
Pulse voltage, waveform etc. import parameter, impacted by the electric pulse of certain energy, being formed on cell membrane can
Inverse passage, makes the genetic stews such as nucleic acid vaccine rapidly enter in cell membrane, and and then into giving expression in nucleus
Antigen, excites vivo immunization reaction.Pulsewidth, the isoparametric selection of frequency are completed by the path for setting.Pass through
Feedback circuit collects feedback information, decides whether output electric pulse.By memory function, realize that channel genes are remembered
The preservation of record, realizes that the machine is exchanged and to the online of user with the information of host computer by information transmission modular
Instruct.
The action principle of system of the invention is：Specific parameter of the invention and electrode shape can be by nucleic acid vaccines
By electric field action, import in target tissue cell.The suitable parameter that imports of design produces material impact to importing.
Unsuitable parameter, can not only increase importing effect, or even can also produce irreversible infringement to body.This
The parameter of invention can effectively improve the importing efficiency of HIV nucleic acid vaccines, strengthen immune effect.
Load 107 connects pulse generation module 103, and the electric pulse for system to be sent is transferred in target tissue.
One embodiment of load 107 is as shown in Figure 5A filiform needle electrode, by electrode tip 1071 and electrode handle 1072
It is formed by connecting, in the groove of the plug insertion electrode handle 1072 of electrode tip 1071, electrode tip Top electrode quantity is
2, electrode spacing 5mm.
One embodiment of load 107 is as shown in Figure 5 B filiform needle electrode, and electrode tip Top electrode quantity is 4
(four round dots shown in Fig. 5 B are electrode, and middle circular hole is injection pin hole), 4 electrode arrangements are into just
It is square, electrode spacing 5mm.
One embodiment of load 107 is as shown in Figure 5 C filiform needle electrode, and electrode tip Top electrode quantity is 4
(four round dots shown in Fig. 5 C are electrode, and middle circular hole is injection pin hole), 4 electrode arrangements are into brill
Stone shape, electrode spacing 6mm.
Those skilled in the art will further appreciate that, the various solutions described with reference to the embodiments described herein
The property said logic plate, module, circuit and algorithm steps can realize for electronic hardware, computer software or this
A combination of both.Clearly to explain this interchangeability of hardware and software, various illustrative components, frame,
Module, circuit and step are to make vague generalization in its functional form to describe above.Such feature is
It is implemented as hardware or software depends on concrete application and puts on the design constraint of total system.Technical staff
Described feature can be realized with different modes for every kind of application-specific, but such realizes decision-making not
Should be interpreted to cause departing from the scope of the present invention.
Various illustrative logic plates, module and the circuit described with reference to presently disclosed embodiment are available logical
With processor, digital signal processor (DSP), application specific integrated circuit (ASIC), field programmable gate array
(FPGA) or other PLDs, discrete door or transistor logic, discrete nextport hardware component NextPort or
Any combinations that it is designed to carry out function described herein are realized or performed.General processor can be micro- place
Reason device, but in alternative, the processor can be any conventional processor, controller, microcontroller,
Or state machine.Processor is also implemented as the combination of computing device, the combination of such as DSP and microprocessor,
One or more microprocessors or any other such configuration that multi-microprocessor cooperates with DSP core.
The method that is described with reference to embodiment disclosed herein or can be embodied directly in hardware, in the step of algorithm by
Embodied in the software module that reason device is performed or in combination of the two.Software module can reside in RAM and deposit
Reservoir, flash memory, ROM memory, eprom memory, eeprom memory, register, hard disk,
In the storage medium of removable disk, CD-ROM or any other form known in the art.It is exemplary to deposit
Storage media is coupled to processor to enable that the processor reads and write-in information from/to the storage medium.Replacing
In scheme, storage medium can be integrated into processor.Processor and storage medium can reside in ASIC.
ASIC can reside in user terminal.In alternative, processor and storage medium can be stayed as discrete assembly
Stay in the user terminal.
In one or more exemplary embodiments, described function can hardware, software, firmware or its
What is realized in combining.If being embodied as computer program product in software, each function can as one or
More a plurality of instruction or code storage are transmitted on a computer-readable medium or by it.Computer-readable medium bag
Both computer-readable storage medium and communication media are included, it includes facilitating computer program to shift from one place to another
Any medium.Storage medium can be any usable medium that can be accessed by a computer.As an example rather than limit
Fixed, such computer-readable medium may include RAM, ROM, EEPROM, CD-ROM or other light
Disk storage, disk storage or other magnetic storage apparatus can be used to carry or store instruction or data structure shape
The desirable program code of formula and any other medium that can be accessed by a computer.Any connection is also properly termed
Computer-readable medium.If for example, software is ordered using coaxial cable, fiber optic cables, twisted-pair feeder, numeral
The wireless technology of family line (DSL) or such as infrared, radio and microwave etc from web site, service
Device or other remote sources are transmitted, then the coaxial cable, fiber optic cables, twisted-pair feeder, DSL or such as
The wireless technology of infrared, radio and microwave etc is just included among the definition of medium.As herein
The disk (disk) and dish (disc) for being used include compact disc (CD), laser disc, laser disc, digital versatile disc
(DVD), floppy disk and blu-ray disc, which disk (disk) often reproduce data in the way of magnetic, and dish (disc)
With laser reproduce data optically.Combinations of the above should also be included within the scope of computer readable media.
It is for so that any person skilled in the art can all make or use this to provide of this disclosure being previously described
It is open.Various modifications of this disclosure all will be apparent for a person skilled in the art, and herein
Defined generic principles can be applied to spirit or scope of other variants without departing from the disclosure.Thus,
The disclosure is not intended to be limited to example described herein and design, but should be awarded and institute herein
Principle disclosed and the consistent widest scope of novel features.
Claims (9)
1. the system that a kind of constant pressure electric pulse imports AIDS nucleic acid vaccine, by AIDS nucleic acid vaccine by low frequency
Electric pulse imports target tissue, it is characterised in that system includes：
Injection device, contains AIDS nucleic acid vaccine；
Electric pulse gatherer, it is further included：
Pulse sets and implements module, receives the electric pulse parameter of user input；
Power module, produces DC signal；
Microcontroller, is set with pulse respectively and implementation module, power module are electrically connected, and is received pulse and is set
The electric pulse parameter of module output is put and implements, according to electric pulse parameter output control signal；
Pulse generation module, and pulse sets and implements module electrical connection, according to control signal by direct current
Into output electric pulse signal after constant pressure electric impulse signal, the waveform of the electric impulse signal of output is symmetrical to signal transacting
Unidirectional continuous impulse square wave is triggered, pulse frequency is 1 to 50Hz, and pulse width is 1ms to 150ms, pulse
Number is 1 to 20；And
Load, and the electrical connection of pulse generation module, receive the electric impulse signal of pulse generation module output.
2. the system that constant pressure electric pulse according to claim 1 imports AIDS nucleic acid vaccine, its feature exists
In electric pulse gatherer also includes：
Information feedback module, respectively with microcontroller, load electrical connection, the portion that detection electric impulse signal is imported
The electric current of position simultaneously feeds back to microcontroller.
3. the system that constant pressure electric pulse according to claim 2 imports AIDS nucleic acid vaccine, its feature exists
In electric pulse gatherer also includes：
Memory module, and microcontroller electrical connection, for storing channel genes record.
4. the system that constant pressure electric pulse according to claim 3 imports AIDS nucleic acid vaccine, its feature exists
In electric pulse gatherer also includes：
Information transmission modular, and microcontroller electrical connection, the information exchange for realizing the machine and host computer.
5. the system that constant pressure electric pulse according to claim 1 imports AIDS nucleic acid vaccine, its feature exists
In the electric impulse signal of, pulse generation module output be 60V constant pressures, pulse width be 50ms, frequency be 1Hz,
Pulse number is the unidirectional continuous impulse square wave of 6.
6. the system that constant pressure electric pulse according to claim 1 imports AIDS nucleic acid vaccine, its feature exists
In the electric impulse signal of, pulse generation module output be 90V constant pressures, pulse width be 50ms, frequency be 1Hz,
Pulse number is the unidirectional continuous impulse square wave of 6.
7. the system that constant pressure electric pulse according to claim 1 imports AIDS nucleic acid vaccine, its feature exists
In the electric impulse signal of, pulse generation module output be 108V constant pressures, pulse width be 30ms, frequency be 1Hz,
Pulse number is the unidirectional continuous impulse square wave of 6.
8. constant pressure electric pulse importing AIDS nucleic acid vaccine according to any one of claim 1 to 7 is
System, it is characterised in that load is filiform needle electrode, and filiform needle electrode is formed by connecting by electrode tip and electrode handle, wherein
The plug of electrode tip is inserted in the groove of electrode handle.
9. the system that constant pressure electric pulse according to claim 8 imports AIDS nucleic acid vaccine, its feature exists
In electrode tip is provided with 2 electrodes and electrode spacing is 5mm；Or electrode tip is provided with square arrangement
4 electrodes and electrode spacing be 5mm；Or electrode tip is provided with 4 electrodes and electricity arranged in diamond
Die opening is 6mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511027117.XA CN106924874A (en) | 2015-12-31 | 2015-12-31 | The system that a kind of constant pressure electric pulse imports AIDS nucleic acid vaccine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201511027117.XA CN106924874A (en) | 2015-12-31 | 2015-12-31 | The system that a kind of constant pressure electric pulse imports AIDS nucleic acid vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106924874A true CN106924874A (en) | 2017-07-07 |
Family
ID=59441897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201511027117.XA Pending CN106924874A (en) | 2015-12-31 | 2015-12-31 | The system that a kind of constant pressure electric pulse imports AIDS nucleic acid vaccine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106924874A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522622A (en) * | 1982-12-23 | 1985-06-11 | Alza Corporation | Multiple fluid pulse dispenser |
| CN101744649A (en) * | 2008-12-16 | 2010-06-23 | 上海塔瑞莎健康科技有限公司 | System for transferring anti-AIDS vaccine |
| CN202920725U (en) * | 2012-10-25 | 2013-05-08 | 陈丽晔 | Medication injection electric leading-in needle device |
| CN203498390U (en) * | 2013-09-25 | 2014-03-26 | 上海塔瑞莎生物技术有限公司 | Gene introduction device for living plants |
-
2015
- 2015-12-31 CN CN201511027117.XA patent/CN106924874A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522622A (en) * | 1982-12-23 | 1985-06-11 | Alza Corporation | Multiple fluid pulse dispenser |
| CN101744649A (en) * | 2008-12-16 | 2010-06-23 | 上海塔瑞莎健康科技有限公司 | System for transferring anti-AIDS vaccine |
| CN202920725U (en) * | 2012-10-25 | 2013-05-08 | 陈丽晔 | Medication injection electric leading-in needle device |
| CN203498390U (en) * | 2013-09-25 | 2014-03-26 | 上海塔瑞莎生物技术有限公司 | Gene introduction device for living plants |
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Application publication date: 20170707 |
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