CN1069210C - Liquid for curing scald and burn and its preparing method - Google Patents

Abstract

The present invention relates to a liquid for curing scalds and burns and a preparing method of the liquid. The liquid is characterized in that every 1000 ml of physic liquor comprises 200 to 300 ml of eucalyptus oil with added borneol, 400 to 560 ml of extracting solutions of rhubarb, black nightshade and elecampane, 150 ml of trimethylene glycol, 40 ml of azone and 60 ml of tween-80. The liquid for curing scalds and burns of the present invention can cure burns and scalds below level 2 within one week and can immediately alleviate pain when coated on wound surfaces. The liquid has favorable pain alleviating, antiinflammatory and infection resistant effects, has strong killing effects on staphylococcus aureus, gram positive bacteria, fungus and pseudomonas aeruginosa and has the advantages of tissue regeneration promotion and detumescence, outstanding curative effects good promotion to granulation tissues newly generating, wound healing promotion, no scars of burns and scalds below level 2 after healing, convenient use, safety and no toxic and side effects or adverse reaction.

Description

A kind of liquid for curing scald and burn and preparation method thereof

The present invention relates to field of pharmaceutical technology, specifically a kind of liquid for curing scald and burn and preparation method thereof.

The burn due to hot liquid or fire reason differs, and as boiling water, steam, roll oil, hot medicated porridge, raging fire, lime water, metallic solution, fulgerize and various chemical substances etc., always is all strong effect infringement human body skins.The lighter does not influence human body viscera, and skin and flesh is rotted; Weight person's (the III degree is above or scalding area is bigger), then the gas of pyretic toxicity is very vehement, can injure cloudy liquid in the body, or pyretic toxicity inside fire attack internal organs, thereby meat is rotted, and also impairment of YIN is decreased sun, and the disease of internal organs discord is occurred in succession.

Existing pharmacopoeia class for the treatment burn and scald is various, is generally paste or medicated powder and transfer applies, its technological method for processing is simple, mostly refuels accent with the crude drug powder, or processes with decocting in water.Though the curative effect that burn and scald is all had nothing in common with each other, in use inconvenient, when changing dressings once more, wound surface easily pollutes, easy cleaning not, and easy damaged new granulation tissue, the easiest generation is subinfection again.Generally can stay cicatrix behind the wound healing, and the effect of antimicrobial spectrum is indeterminate.And the medicine that the water boiling is got is also apt to deteriorate.

The purpose of this invention is to provide a kind of heat-clearing and toxic substances removing that has, the pathogenic fire purging pain relieving, infection, easy to use, the burn and scald of skin there is liquid for curing scald and burn of good result and preparation method thereof.

Liquid for curing scald and burn of the present invention adopts following prescription and preparation method:

Prescription: per thousand milliliters contain eucalyptus oil and add Borneolum Syntheticum 200-300 milliliter, Radix Et Rhizoma Rhei, Herba Solani Nigri, Radix Inulae extracting solution 400-560 milliliter, 150 milliliters of propylene glycol, 40 milliliters of azones, 60 milliliters of tween 80s.

Radix Et Rhizoma Rhei 600-700 gram, Herba Solani Nigri 500-600 gram, Radix Inulae 100-200 gram adds ethanol and gets extracting solution 400-560 milliliter.

The Borneolum Syntheticum that adds in the eucalyptus oil is the 10-15 gram.

The preparation method of above-mentioned prescription liquid for curing scald and burn is:

1) with Radix Inulae, Radix Et Rhizoma Rhei, Herba Solani Nigri weighing decontamination in proportion, break into coarse powder respectively and cross sieve No. 2, behind their mixings, with 90-95% alcohol-pickled 2 days, ethanol should surpass 10 centimetres of powder, slowly emit medicinal liquid, with medicinal liquid put back again soak again in the medicinal residues 2 die young after, slowly emit the about 400-560 milliliter of medicinal liquid, filter standby, extractum relative density 0.85-0.90;

2) fully dissolve Borneolum Syntheticum several times by measuring eucalyptus oil, filtration, waste slowly add with tween 80, and the limit edged stirs, and slowly adds propylene glycol again, and the limit edged stirs, and makes it fully emulsified;

3) with 1) extractum that makes slowly adds 2) emulsion in, the limit edged stirs to medicinal liquid does not have muddiness, elaioleucite shape;

4) slowly add in the medicinal liquid by measuring azone, the limit edged stirs, and makes it fully emulsified, and standing over night is filtered, and promptly gets this liquid for curing scald and burn.

Formulation analysis: eucalyptus oil nature and flavor toil, cold, its effect are pathogenic fire purging poison clearly, can control the dense disease of erysipelas and other infectiousnessization, burn and scald, traumatic hemorrhage etc.Radix Et Rhizoma Rhei nature and flavor bitter cold, its effect are that pathogenic fire purging poison, clots absorbing blood removing mass stagnate, and above-mentioned two flavor medicines are the monarch drug in the present invention's prescription.It is swollen that Herba Solani Nigri nature and flavor bitter cold, its effect are that heat-clearing and toxic substances removing is invigorated blood circulation, and cures mainly the various inflammation of skin, has good antiinflammatory action, the ministerial drug in the present invention's prescription.Radix Inulae, Borneolum Syntheticum are adjuvant.Wherein the Radix Inulae nature and flavor are bitter warm, promoting the circulation of QI to relieve pain; The Borneolum Syntheticum nature and flavor are arduous cool, and reducing swelling and alleviating pain has bacteriostasis external, but training the mind dysmenorrhoea or antiinflammatory, and mucosa, subcutaneous tissue all easily absorb, and match fragrant odour, but putrefaction-removing granulation-promoting subduing swelling and relieving pain with eucalyptus oil.More than all medicines compatible, messenger drug has clearing away heat-fire poison, subduing swelling and relieving pain antiinflammatory anti-infective good result.

Liquid for curing scald and burn of the present invention is through repeatedly experiment clinically, and hundred routine extreme misery burn and scald checkings of treatment: burn and scald week within the II degree can cure, and spread on pain relieving immediately on the wound surface, little chickenpox person is arranged, can absorb voluntarily in four days, this medicine analgesic effect of the chickenpox person of breaking external application is fine, again can the antiinflammatory infection, the dried bacterium of staphylococcus aureus, gram-positive bacterium, fungus and green pus there is stronger killing action.This product energy muscle-growing and detumescence, determined curative effect has facilitation preferably to new granulation tissue, can promote wound healing, and is with interior burn and scald healing preventing from scar, easy to use at the II degree, safety non-toxic effect of paying and untoward reaction.

The invention will be further described below in conjunction with embodiment.

Embodiment 1, and the technology step is poly-as follows:

1, extractum preparation:

1) Radix Aucklandiae 100 gram that fetches earth, Radix Et Rhizoma Rhei 650 grams, Herba Solani Nigri 600 grams, the selection decontamination breaks into coarse powder respectively, crosses sieve No. 2;

2) with medicated powder in proportion behind the mixing, with alcohol-pickled 2 days of 90-95%, ethanol should surpass 10 centimetres of powder, checks, supplies ethanol every day;

3) slowly emit above-mentioned medicinal liquid, with medicinal liquid put back again soak 2 days again in the medicinal residues after, slowly emit medicinal liquid, filter standby:

4) medicinal residues reuse 90-95% is alcohol-pickled;

The relative density 0.85-0.90 of gained extractum must measure about 450 milliliters;

2, allotment

1) gets 250 milliliters of 300 milliliters of usefulness of eucalyptus oil and fully dissolve 15 gram Borneolum Syntheticums, filtration, waste several times;

2) add remaining 50 milliliters of eucalyptus oil mixings in the filtrate;

3) measure 60 milliliters of tween 80s, slowly add aforesaid liquid, the limit edged stirs;

4) measure propylene glycol and slowly add aforesaid liquid for 150 milliliters, the limit edged stirs, and makes it fully emulsified;

5) measure extractum and slowly add aforesaid liquid for 450 milliliters, the limit edged stirs, and liquid should not have muddiness, elaioleucite phenomenon;

6) measure azone and slowly add aforesaid liquid for 40 milliliters, the limit edged stirs and makes it fully emulsified, leaves standstill liquid, filters, and promptly gets 1000 milliliters of medicinal liquids of the present invention, and medicinal liquid is brownish red;

7) sub-bottle packaging.

Embodiment 2,

1, extractum preparation:

1) Radix Aucklandiae 200 gram that fetches earth, Radix Et Rhizoma Rhei 700 grams, Herba Solani Nigri 550 grams, the selection decontamination breaks into coarse powder respectively, crosses sieve No. 2;

2) with medicated powder in proportion behind the mixing, with alcohol-pickled 2 days of 90-95%, ethanol should surpass 10 centimetres of powder, checks, supplies ethanol every day;

3) slowly emit above-mentioned medicinal liquid, with medicinal liquid put back again soak 2 days again in the medicinal residues after, slowly emit medicinal liquid, filter standby;

4) medicinal residues reuse 90-95% is alcohol-pickled;

The relative density 0.85-0.90 of gained extractum must measure about 500 milliliters;

2, allotment

1) gets 200 milliliters of 250 milliliters of usefulness of eucalyptus oil and fully dissolve 13 gram Borneolum Syntheticums, filtration, waste several times;

2) add remaining 50 milliliters of eucalyptus oil mixings in the filtrate:

3) measure 60 milliliters of tween 80s, slowly add 2) medicinal liquid, the limit edged stirs:

4) measure propylene glycol and slowly add 3 for 150 milliliters) medicinal liquid, the limit edged stirs, and makes it fully emulsified;

5) measure the slow silk ribbons attached to an official seal or a medal of 500 milliliters of extractum and add 4) medicinal liquid, the limit edged stirs, liquid should not have muddiness, elaioleucite phenomenon;

6) measure azone and slowly add 5 for 40 milliliters) medicinal liquid, the limit edged stirs and makes it fully emulsified, leaves standstill liquid, filters, and promptly gets 1000 milliliters of medicinal liquids of the present invention, medicinal liquid is brownish red;

7) sub-bottle packaging.

Claims (2)

1, a kind of liquid for curing scald and burn is characterized in that: per thousand milliliters contain eucalyptus oil and add Borneolum Syntheticum 200-300 milliliter, Radix Et Rhizoma Rhei, Herba Solani Nigri, Radix Inulae extracting solution 400-560 milliliter, 150 milliliters of propylene glycol, 40 milliliters of azones, 60 milliliters of tween 80s; Wherein, the Borneolum Syntheticum that adds in the eucalyptus oil is the 10-15 gram, adds ethanol and gets extracting solution 400-560 milliliter with Radix Et Rhizoma Rhei 600-700 gram, Herba Solani Nigri 500-600 gram, Radix Inulae 100-200 gram.

2, the preparation method of liquid for curing scald and burn according to claim 1 is characterized in that:

1) with Radix Inulae, Radix Et Rhizoma Rhei, imperial Cai weighing decontamination in proportion, break into coarse powder respectively and cross sieve No. 2, behind their mixings, die young with 90-95% alcohol-pickled 2, ethanol should surpass 10 centimetres of powder, slowly emits medicinal liquid, with medicinal liquid put back again soak 2 days again in the medicinal residues after, slowly emit the about 400-560 milliliter of medicinal liquid, filter standby, extractum relative density 0.85-0.90;

2) fully dissolve Borneolum Syntheticum several times by measuring eucalyptus oil, filtration, waste slowly add with tween 80, and the limit edged stirs, and slowly adds propylene glycol again, and the limit edged stirs, and makes it fully emulsified;

3) with 1) extractum that makes slowly adds 2) emulsion in, the limit edged stirs to medicinal liquid does not have muddiness, elaioleucite shape;

4) slowly add in the medicinal liquid by measuring azone, the limit edged stirs, and makes it fully emulsified, and standing over night is filtered, and promptly gets this liquid for curing scald and burn.