CN106913304A - A kind of spectrum rigid pipe endoscope system - Google Patents

A kind of spectrum rigid pipe endoscope system Download PDF

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Publication number
CN106913304A
CN106913304A CN201510998109.3A CN201510998109A CN106913304A CN 106913304 A CN106913304 A CN 106913304A CN 201510998109 A CN201510998109 A CN 201510998109A CN 106913304 A CN106913304 A CN 106913304A
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CN
China
Prior art keywords
rigid pipe
spectrum
pipe endoscope
image
endoscope system
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Pending
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CN201510998109.3A
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Chinese (zh)
Inventor
刘小华
王夏天
董立泉
程德文
黄庆梅
赵达尊
袁野
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Liu Xiaohua
Original Assignee
WTI (BEIJING) ASIA-PACIFIC PHOTOELECTRIC INSTRUMENT Co Ltd
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Application filed by WTI (BEIJING) ASIA-PACIFIC PHOTOELECTRIC INSTRUMENT Co Ltd filed Critical WTI (BEIJING) ASIA-PACIFIC PHOTOELECTRIC INSTRUMENT Co Ltd
Priority to CN201510998109.3A priority Critical patent/CN106913304A/en
Publication of CN106913304A publication Critical patent/CN106913304A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00002Operational features of endoscopes
    • A61B1/00004Operational features of endoscopes characterised by electronic signal processing
    • A61B1/00009Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00131Accessories for endoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163Optical arrangements
    • A61B1/00195Optical arrangements with eyepieces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/063Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for monochromatic or narrow-band illumination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0661Endoscope light sources
    • A61B1/0684Endoscope light sources using light emitting diodes [LED]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Signal Processing (AREA)
  • Endoscopes (AREA)

Abstract

The invention discloses a kind of spectrum rigid pipe endoscope, the spectral line reflected using spectrometer collection monochromatic illumination light source irradiation tissue surface can be realized being analyzed the pathology of diseased region using the information included in spectrum, be advantageously implemented accurate diagnosis and treatment;Using bio-tissue to the otherness of different wave length luminous energy absorptivity, the monochromatic light of different colours is produced by the lighting source installed in hard tube mirror the inside foremost, different monochromatic images can be obtained, this spectrum hard tube mirror system can be substantially improved the resolution ratio of image;And the method for passing through Image Information Processing, will can show by the result after lifting under different depth using image interfusion method therein on the basis of picture quality is further enhanced in piece image.

Description

A kind of spectrum rigid pipe endoscope system
Technical field
The present invention relates to spectral technique, Image Information Processing, medical science detection, tumor screening field, it is more particularly to a kind of Spectrum rigid pipe endoscope system.
Background technology
With the fast development of society, application of the medical endoscope on clinic diagnosis is more and more extensive.It has volume It is small, many advantages, such as easy to operate, inside of human body can be insinuated into and observed.For medical endoscope, it is applied to The extensive degree of clinic diagnosis proposes strong demand for the development of its correlation technique.What it developed focuses on:How Further improve image quality and how to obtain more rich information.
At present, representative for raising image quality is that narrow band imaging (NBI) can smart electronicses with Fuji Light splitting technology (FICE), the latter turns into many bands imaging technique (MBI) or computer virtual Endoscopy (CVC) again.Two kinds of technologies Common advantage is the contrast that can increase image, the abundant picture rich in detail of grain details is obtained, for diagnosis and treatment provide facility Condition, but weak point is there is also, for the former, it is disadvantageous in that high cost, power consumption are big;For the latter, weak point It is that contrast lifting degree is not obvious enough.Also, at present in endoscope condition-inference field still with including in image Information as exclusive diagnosis foundation, for the poor information full appreciation that lesion locations are included in spectral line, and spectrum skill Art diagnosis and treatment have been obtained for being widely applied the characteristics of efficient, accurate with its in many fields of state of an illness diagnosis and treatment, therefore, if will Spectral technique is combined with endoscopic imaging technology, the accuracy of, Accurate Analysis quick for the pathology cycle and early diagnosis Etc. aspect will effectively improve.
The content of the invention
In view of this, the invention provides a kind of spectrum rigid pipe endoscope system, lesion region spectral information can be obtained, Image resolution ratio can also be greatly improved, strengthens picture contrast, real-time spectrum rigid pipe endoscope and system, carried out the state of an illness and examine Accurate Analysis can be carried out while disconnected to the pathology cycle, early stage condition-inference ability is improved.
A kind of spectrum rigid pipe endoscope system of the invention, including rigid pipe endoscope, light-dividing device, imaging detection device, Calculate display device and spectrometer;
The rigid pipe endoscope uses monochromatic lighting source, for carrying out monochromation illumination to bio-tissue to be seen;
The light of the bio-tissue surface reflection that the light-dividing device receives rigid pipe endoscope is divided into two parts, a part Imaging detection device is passed to, another part passes to spectrometer;
The imaging detection device, gathers the image on the bio-tissue surface, and image input is calculated into display device;
The spectrometer, receives the optical signal data of bio-tissue surface reflection, and is transmitted to calculate display device;
It is described to calculate the image that display device shows the bio-tissue surface, directly observed for medical personnel;Meanwhile, to institute State optical signal data to be processed, obtain the spectral line of bio-tissue, pathology location is diagnosed for medical personnel.
Preferably, the monochromatic illumination light source is placed in the front end of the rigid pipe endoscope.
Preferably, the monochromatic illumination light source can timesharing conversion different colours, it is included in rigid pipe endoscope front edge Anchor ring on uniform 6 LED chips, centrosymmetric two LED chips are one group each other, produce the light bag of same color Include green, blue, red(Or it is infrared).
Preferably, monochromatic illumination light source is included in 6 LED cores uniform on the anchor ring of rigid pipe endoscope front edge Piece, produces the light of same color;The color of light is red(Or it is infrared), green or blue.
Preferably, also including control circuit;The control circuit includes dc source, current-limiting resistance and three switches;Respectively One end of switch connects the anode of dc source by current-limiting resistance, after one group of LED chip of same color of another termination of switch Connect the negative terminal of dc source.
Preferably, the rigid pipe endoscope is included in objective lens, rod microscope group, the eyepiece being sequentially arranged from front to back in telescope Group, main mirror and supplying channels;Supplying channels are monochromatic illumination light source power supply by being close to the wire of telescope inner surface.
Preferably, the calculating display device is carried out to bio-tissue surface image formed by different colours lighting source Following treatment technology, including:Image noise reduction, image enhaucament and image co-registration.
Preferably, the image co-registration for calculating display device uses linear weighted function fusion method.
Preferably, the image co-registration for calculating display device uses principal component analysis fusion method.
The present invention has the advantages that:
(1)The spectral line that the present invention is reflected using spectrometer collection monochromatic illumination light source irradiation tissue surface, using in spectrum Comprising information can realize being analyzed the pathology of diseased region, be advantageously implemented accurate diagnosis and treatment;Using bio-tissue To the otherness of different wave length luminous energy absorptivity, can be obtained by the different monochromatic illumination light sources installed in hard tube mirror the inside foremost Different monochromatic images are taken, this spectrum hard tube mirror system can be substantially improved the resolution ratio of image;
(2)The present invention, can be on the basis of picture quality be further enhanced, using image therein by Image Information Processing Fusion method can show the result after being lifted under different monochromatic illuminations in piece image.
(3)The present invention by using single tube endoscope, compared to traditional two-tube endoscope, due to eliminating inner tube, outward Space inside pipe is increased, and internal objective lens, rod microscope group and eyepiece group enlarged diameter, image resolution ratio are dramatically increased.
Brief description of the drawings
Fig. 1 is the structural representation of spectrum rigid pipe endoscope system of the present invention.
Fig. 2 is the functional block diagram of spectrum rigid pipe endoscope system of the present invention.
Fig. 3 is the spectrum rigid pipe endoscope structural representation of spectrum rigid pipe endoscope system of the present invention.
Fig. 4 is the spectrum rigid pipe endoscope front end face schematic diagram of spectrum rigid pipe endoscope system of the present invention.
Fig. 5 is the monochromatic source power supply circuit schematic diagram of spectrum rigid pipe endoscope system of the present invention.
1- rigid pipe endoscopes, 2- light-dividing devices, 3- imaging detection devices, 4- spectrometers, 5- calculates display device, 6- things Microscope group, 7- rod microscope groups, 8- eyepiece groups, 9- monochromatic illumination light sources, 10- wires, 11- telescopes, 12- main mirrors, 13- supplying channels.
Specific embodiment
Develop simultaneously embodiment below in conjunction with the accompanying drawings, and the present invention will be described in detail.
As the side that a kind of spectrum rigid pipe endoscope system, the present invention are combined using Image Information Processing with spectrum analysis Method, is detected by rigid pipe endoscope 1 first, is then received respectively through imaging detection device 3 and spectrometer 4, will Data send computing device to and process obtaining result.Therefore, spectrum rigid pipe endoscope system of the invention refers to hard tube Endoscopic imaging has the summation of all devices of analysis, treatment and display function.
Spectrum rigid pipe endoscope system of the invention, including:Rigid pipe endoscope 1, monochromatic illumination light source 9, light-dividing device 2, Imaging detection device 3, calculating display device 5 and spectrometer 4.
The rigid pipe endoscope 1 using monochromatic illumination light source 9, can timesharing conversion different colours, be positioned over telescope front end, and The working condition that different colours are produced to it by circuit is controlled.
The display device 5 that calculates is used to complete the calculating and treatment work of view data and spectroscopic data, and treatment is tied Fruit is shown.
The light-dividing device 2, two parts are divided into by the light path of the image space of the optical imaging system of rigid pipe endoscope 1.One Part passes to imaging detection device 3, and another part passes to spectrometer 4.
The imaging detection device 3, collection monochromatic source irradiates the image of organism surface, and image input is calculated into display Equipment 5 is directly observed or is carried out for medical personnel image procossing and observed.
The spectrometer 4, receives the reflected light signal formed when bio-tissue irradiates by monochromatic source, by collection Device transfers data to computing device, by the light for reflecting monochromatic source irradiation biological tissue surface after computing device treatment Spectral pattern is presented on the display device, there is provided the spectral information of biological tissue surface, allows medical personnel in spectrum analysis Method is diagnosed to pathology location.
The system workflow is:The monochromatic source 9 of the front end of rigid pipe endoscope 1 irradiates object under test surface, warp after lighting After crossing the optical system imaging of rigid pipe endoscope 1, be split 2 points of device of output light is two-way, wherein being entered as all the way as visiting Survey device 3, gather image and send into calculating display device 5 directly display or by after Image Information Processing show.At the same time, Another road input light spectrometer 4, result is sent to calculating display device 5 after internal circuit carries out data processing, shows light The spectrogram that source is irradiated behind surface to be measured.Medical personnel can carry out qualitative disease by the image on display device to ad-hoc location Reason inspection, is tentatively judged the state of an illness.If it find that the position truly has the state of an illness, it is necessary to further look at, can be by the position The spectrum information included in spectral line carries out quantitative expedition, so as to fully understand the state of an illness.
As shown in figure 3, rigid pipe endoscope of the invention 1 uses single tube endoscope, including:Objective lens 6, rod microscope group 7, eyepiece Group 8, monochromatic source 9, wire 10, telescope 11, main mirror 12, supplying channels 13.Supplying channels 13 are by being close to table in telescope 11 The wire 10 in face is powered for monochromatic source 9, as shown in figure 4, monochromatic illumination light source 9 is included in the front edge of rigid pipe endoscope 1 6 LED chips uniform on anchor ring, produce the light of same color, and the color of light is red(Or it is infrared), green or blue, The color and number of light source can also be adjusted according to practical use.In view of 2 luminosity of symmetrical LED chip May be not enough, such as during thinner hard tube mirror, 6 LED chips can be arranged to identical color, specific color also according to Way is selected.
As shown in figure 5, control circuit includes dc source, current-limiting resistance and three switches;Controlled with three switches respectively Three monochromatic sources of parallel connection of system, one end of each switch connects the anode of dc source, another termination of switch by current-limiting resistance The LED chip of one group of same color is followed by the negative terminal of dc source.Current-limiting resistance is set, reduces load end electric current, prevent from damaging Monochromatic illumination light source 9, it is possible to which light-source brightness control circuit is increased according to practical use.
It is of the invention to calculate display device 5 also comprising the Image Information Processing function of the enhancing picture quality of rigid pipe endoscope 1, Predominantly:Image noise reduction, image enhaucament, image co-registration etc., include various processing methods in each class.The present invention enumerates two kinds of figures As the method for fusion:Linear weighted function fusion method, principal component analysis fusion method.
Linear weighted function fusion is to be weighted superposition to the corresponding pixel points of the image of two width same sizes.Weighted Fusion table It is as follows up to formula:
The purpose of principal component analysis fusion method is to determine Weighted Fusion coefficient by principal component analysis, finally using the two coefficients Linear weighted function fusion is carried out to image.It is in order to obtain an optimal weighted fusion coefficient, so that after fusion using the method Picture quality it is optimal.The step of principal component analysis fusion method is:
1st, according to raw image data matrix, obtain its covariance matrix
2nd, covariance matrix is calculatedCharacteristic value and characteristic vector.
3rd, covariance matrix is calculatedCharacteristic value and characteristic vector, by the descending arrangement of characteristic value after, by each feature It is worth corresponding characteristic vector according to this sequential build transformation matrix, and it is rightColumn vector carry out it is unitization.
4th, by transformation matrixWith original imageCarry out matrix multiplication operation,Row vector be exactly image Each principal component component.
5th, weight coefficient is determined by principal component component.
In sum, presently preferred embodiments of the present invention is these are only, is not intended to limit the scope of the present invention. All any modification, equivalent substitution and improvements within the spirit and principles in the present invention, made etc., should be included in of the invention Within protection domain.

Claims (10)

1. a kind of spectrum rigid pipe endoscope system, it is characterised in that including rigid pipe endoscope(1), light-dividing device(2), imaging visit Survey device(3), calculate display device(5)And spectrometer(4);
The rigid pipe endoscope(1)Using monochromatic lighting source(9), for carrying out monochromatic light to bio-tissue to be seen Illumination;
The light-dividing device(2)By rigid pipe endoscope(1)The light of the bio-tissue surface reflection for receiving is divided into two parts, A part passes to imaging detection device(3), another part passes to spectrometer(4);
The imaging detection device(3), the image on the bio-tissue surface is gathered, image input is calculated into display device (5);
The spectrometer(4), the light of bio-tissue surface reflection is received, and spectroscopic data is formed, and be transmitted to calculate Display device(5);
The calculating display device(5)The image on the bio-tissue surface is shown, is directly observed for medical personnel;Meanwhile, The spectral line of bio-tissue is obtained according to the spectroscopic data, pathology location is diagnosed for medical personnel.
2. a kind of spectrum rigid pipe endoscope system as claimed in claim 1, it is characterised in that the lighting source(9)It is placed in The rigid pipe endoscope(1)Front end.
3. a kind of spectrum rigid pipe endoscope system as claimed in claim 2, it is characterised in that the lighting source(9)Including N Individual LED chip, is distributed in the rigid pipe endoscope(1)Front edge anchor ring on.
4. a kind of spectrum rigid pipe endoscope system as claimed in claim 3, it is characterised in that the lighting source(9)List Coloured light color is at least red, green, blue color or infrared one of which.
5. a kind of spectrum rigid pipe endoscope system as claimed in claim 4, it is characterised in that the lighting source(9)Can divide Shi Bianhuan different colours.
6. a kind of spectrum rigid pipe endoscope system as claimed in claim 5, it is characterised in that the lighting source(9)Including In rigid pipe endoscope(1)6 LED chips uniform on the anchor ring of front edge, each other centrosymmetric two LED chips be One group, produce the monochromatic light of same color.
7. a kind of spectrum rigid pipe endoscope system as described in claim 3 or 4, it is characterised in that also including control circuit;Should Control circuit includes dc source, current-limiting resistance and three switches;One end of each switch connects dc source by current-limiting resistance Anode, the LED chip of one group of same color of another termination of switch is followed by the negative terminal of dc source.
8. a kind of spectrum rigid pipe endoscope system as described in claim 1,2,3 or 4, it is characterised in that peeped in the hard tube Mirror(1)It is single tube endoscope, is included in telescope(11)In be sequentially arranged in telescope from front to back(11)Internal objective lens(6)、 Rod microscope group(7), eyepiece group(8), main mirror(12)And supplying channels(13);Supplying channels(13)By being close to telescope(11)It is interior The wire on surface(10)It is lighting source(9)Power supply.
9. a kind of spectrum rigid pipe endoscope system as claimed in claim 1, it is characterised in that the calculating display device(5) Technology is handled as follows to bio-tissue surface image formed by different colours lighting source, including:Image noise reduction, image Enhancing and image co-registration.
10. a kind of spectrum rigid pipe endoscope system as claimed in claim 9, it is characterised in that the calculating display device(5) Image co-registration use principal component analysis fusion method or linear weighted function fusion method.
CN201510998109.3A 2015-12-28 2015-12-28 A kind of spectrum rigid pipe endoscope system Pending CN106913304A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110084808A (en) * 2019-05-06 2019-08-02 智影汇谱(宁波)科技有限公司 A kind of color solution mixing method and image processing apparatus for digital endoscope
CN113448074A (en) * 2020-03-25 2021-09-28 北京威斯顿亚太光电仪器有限公司 Illumination light source of disposable hard tube mirror
CN116725467A (en) * 2023-03-31 2023-09-12 苏州宇懋医学科技有限公司 Endoscope device, endoscope medical assistance system, and endoscope image processing method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020173723A1 (en) * 1999-07-02 2002-11-21 Lewis Edgar N. Dual imaging apparatus
JP2006061457A (en) * 2004-08-27 2006-03-09 Olympus Corp Fluorescence endoscope and probe device for fluorescence endoscope
CN101904737A (en) * 2010-08-09 2010-12-08 华中科技大学 Living body fluorescent endoscopic spectrum imaging device
CN105054890A (en) * 2015-09-07 2015-11-18 中国医学科学院生物医学工程研究所 Tumor tissue detection device based on endoscope
CN205493762U (en) * 2015-12-28 2016-08-24 北京威斯顿亚太光电仪器有限公司 Spectrum hard tube endoscope system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020173723A1 (en) * 1999-07-02 2002-11-21 Lewis Edgar N. Dual imaging apparatus
JP2006061457A (en) * 2004-08-27 2006-03-09 Olympus Corp Fluorescence endoscope and probe device for fluorescence endoscope
CN101904737A (en) * 2010-08-09 2010-12-08 华中科技大学 Living body fluorescent endoscopic spectrum imaging device
CN105054890A (en) * 2015-09-07 2015-11-18 中国医学科学院生物医学工程研究所 Tumor tissue detection device based on endoscope
CN205493762U (en) * 2015-12-28 2016-08-24 北京威斯顿亚太光电仪器有限公司 Spectrum hard tube endoscope system

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110084808A (en) * 2019-05-06 2019-08-02 智影汇谱(宁波)科技有限公司 A kind of color solution mixing method and image processing apparatus for digital endoscope
CN113448074A (en) * 2020-03-25 2021-09-28 北京威斯顿亚太光电仪器有限公司 Illumination light source of disposable hard tube mirror
CN116725467A (en) * 2023-03-31 2023-09-12 苏州宇懋医学科技有限公司 Endoscope device, endoscope medical assistance system, and endoscope image processing method
CN116725467B (en) * 2023-03-31 2024-03-01 苏州宇懋医学科技有限公司 Endoscope device, endoscope medical assistance system, and endoscope image processing method

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