CN106901729B - A kind of medication coat for backbone reduction system - Google Patents
A kind of medication coat for backbone reduction system Download PDFInfo
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- CN106901729B CN106901729B CN201710062452.6A CN201710062452A CN106901729B CN 106901729 B CN106901729 B CN 106901729B CN 201710062452 A CN201710062452 A CN 201710062452A CN 106901729 B CN106901729 B CN 106901729B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/004—Magnetotherapy specially adapted for a specific therapy
- A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Abstract
The medication coat used in a kind of backbone reduction device, the backbone reduction system are treated for the slight contracture of muscle and muscle tonue caused by the reasons such as modern's bad life habits and disease.Muscular tone, which mostly occurs, to be adhered in backbone both sides or is associated on muscle group, and long will cause backbone fatigue, overload even to deform.It is proved to be effective treatment means by applying the alleviation muscle tonue such as machinery, electric field while implementing spinal traction, fixing in spine recovering field.The present invention provides a variety for the treatment of means, and is effectively combined electricity, magnetic treatment.By human body muscle tonue related neural section induced discharge, improve a variety of muscle health indexs effectively;Adaptivity adjustment is carried out in real time in combination with checking with EMG method to obtain better healing effect.Drug of the present invention is added in above process to form the uncomfortable feeling during Neural stem cell can be effectively relieved and increase medication effect for physical therapy.
Description
Technical field
This application involves spine recovering fields, and in particular to the convalescence device of a kind of backbone and muscle.
Background technology
Modern causes body a part to be chronically at due to seat work, bad life habits and disease or certain
Anchor, muscle are chronically at the state of underload contracts last.This can cause moisture in the fibr tissues matrix such as ligament to subtract
Few, viscoelasticity weakens, and interfibrous lubricating action reduces.Meanwhile interfibrous hypotelorism, contact phase extend, this may lead
It causes to generate the horizontal key of chemistry between fiber, stick together so as to cause between fiber.And such crowd is often because of the chronic inflammation of muscular tissue
Disease and lead to newborn fiber, these newborn fiber alignments are disorderly, form adhesion again with original fiber, further limit fibre
Sliding between dimension.Long it, this " vicious circle " will cause muscle that slight contracture occurs, and cause muscle tonue.The life of modern
Mode living determines that such muscle tonue mostly occurs on backbone attachment or sizes related muscle group, and long will cause backbone tired
The appearance of labor, overload or even irreversible damage.
Implementing spinal traction, fixation simultaneously by applying the alleviation muscle tonue quilt such as machinery, electric field in spine recovering field
It is proved to be effective treatment means.But the unnecessary damage of backbone, or even meeting should be inevitably caused in the process
(spinal cord injury, SCI) is damaged to spinal cord, and medical personnel often is reluctant to adopt in order to avoid the damage
With positive therapeutic scheme.Unexpected massage damage also often occurs in the massage processes of non-spinal damage simultaneously.So
It needs to provide effectively real-time electrophysiologic monitoring means when being related to spinal treatments.How electro physiology to be detected and a variety of backbone health
It is a direction that this field has much development prospect that multiple means, which combine,.It is obtained in numerous electrophysiological indexs effectively and has generation
The data of table, and with the emphasis of its progress and this field research of instructing follow-up spine recovering.
Neuro electromyograph is stimulated by the energy of diversified forms, to organism according to Nervous System Anatomy principle
The technology that the electrical characteristics of bioelectricity and organism that peripheral nerve generates are measured, record and analyzed.Evoked ptential (evoked
Potentials, EPs), refer to giving nervous system (from receptor to cerebral cortex) specifically stimulation (sound, light or body-sensing thorn
Swash), or brain is made to be processed the information of stimulation (positivity or negativity), it can be examined in the generation of the corresponding site of the system and brain
It is going out, have with stimulation and be relatively fixed time interval (relationship when lock) and the bioelectricity of certain bits phase reacts.It reflects cynapse biography
It passs, the integrality of the cell of axon conduction and molecular system structure and function, is a kind of effective functional attributes.
Electromyography signal (EMG) is a kind of adjoint muscular movement and the bioelectrical signals generated.In the limb motion of people, greatly
The neuronal excitation in controlled motion region and the electric pulse of certain frequency is generated in cortex, this electric pulse passes through nervous system
Specific meat fiber is accurately conducted, when these electric pulses reach a neural muscle cynapse, soleplate is generated in muscle fibre
Current potential, its depolarising will generate a series of movements current potential in muscle fibre, and cause contraction of muscle, and limbs is made to complete set by brain
Action.Surface EMG is the synthesis physiology electrical phenomena that each section muscle activity is generated in limb motion, is divided surface EMG
Analysis research can find its correspondence between muscle physiological state and limb motion patterns, can be widely applied to clinical doctor
The numerous areas such as, sports medical science, medical rehabilitation.In human skeletal muscle, there are Severe Pain points in muscle muscle tonue band
The viewpoint of (myofascial trigger point, MTrP) is widely recognized as.It can be recorded in the areas MTrP of muscle tonue band
To spontaneous electrical activity, further, muscular tone can also be showed and is detected in the form of myoelectricity.Flesh in simple terms
Meat makes expression by electricity physiological signal to its physiological status (stressing myotonic physiological status in the present invention to state);In turn
Adjusting appropriate can also be made to muscle tonue in such a way that impressed field influences myoelectricity.
It exists in the prior art by carrying out electro photoluminescence to patient and receiving myoelectricity/biofeedback signals of patient, to
Reaching improves the method and apparatus of muscular tone.But these devices use simple electrode stimulating, frequency be located substantially at 5Hz~
Between 100Hz, electric signal includes that waveform is simple.It is single to the effect of stimulation of human body, be easy to cause peripheral nerve fatigue and production
Raw a large amount of unnecessary electrode heat.Skin keratin lesion may then be led to and bring unnecessary damage by being inserted into electrode or patch electrode
Wound.Patient will produce the unnecessary imagination for intuitive visible electrode stimulating, and such psychology also results in therapeutic effect deterioration.
Most importantly peripheral nerve may react good for stimulating in short term, but long-term treatment can cause neural fatigue, effect also can
It is plummeted.Reason is in evolutionary process that human nerve stress reflect the injury that environmental stimuli generates that there are one adapted to
Journey.And the human body self neural electricity including neuromere is then less prone to such fatigue, its fatigue endurance phase is longer in other words.
Neuromere be the identical neuron cell body of function other than the maincenter around nodositas structure made of the set of position
It makes.Its surface is surrounded by one layer of connective tissue membrane, wherein containing blood vessel, nerve and adipocyte.Envelope and perineural outer membrane, god
It connects together through beam film, and gos deep into neuromere forming the network in neuromere.The fiber sent out by nerve cell in section
It is distributed to the related part of body, claims postganglionic fibers.By the difference of physiology and form, neuromere can be spinal ganglion (sensibility god
Warp knuckle) and two class of automatic ganglia.Cerebrospinal ganglion functionally belongs to sensory neuron, morphologically belong to false monopole or
Bipolar neuron.Automatic ganglia includes sympathetic and parasympathetic ganglion.Sympathetic ganglion is located at backbone both sides.Parasympathetic god
Warp knuckle is located near institute's dominating organs or in organ walls.In neuromere, aixs cylinder and the postganglionic neuron group of preganglionic neuron
At cynapse.Neuromere is associated by nerve fibre with brain, spinal cord.
Inventor is tested by the physiology that laboratory carries out and is found:By stimulating the nervous system including neuromere to lead
Cause the bioelectricity that human body generates inaccurate controllable in amplitude, frequency, and the bioelectricity peomotes the controlled muscle of nerve, knot
Form group with being woven with the rhythm and pace of moving things diastole, contraction and the blood circulation of tip fine vascular.It will also be led for ganglionic stimulation simultaneously
Effect of the ascending nerve fiber to brain is caused, there is reduction of patient anxiety, anxiety in practice, it is tight for flesh caused by nerve
Opening has certain therapeutic effect.But inevitably there is a situation where being interfered with each other with electrocardiosignal during Neural stem cell,
Above-mentioned interference can also be improved in such a way that electrocardio triggers magnetic stimulation circuit while being shielded, this is also this field skill
Art personnel are difficult to technical problem urgently to be resolved hurrily.Meanwhile how easy quickly and non-invasively stimulation sites to be accurately positioned
It is then the problem that those skilled in the art do not overcome.Previous physical therapy practitioner often through experience press and patient feedback into
Row positioning, both inaccuracy may also cause accidental injury in this way;Certainly also it has been proposed that being measured by adding electrode, still
Laboratory environment and clinic differ greatly, and testing cost is high very high simultaneously for operator's requirement.
Invention content
The present invention provide it is a kind of alleviate for patient spine damage, backbone fatigue and related muscle group anxiety, treatment it is whole
Complex system.The shortcomings that can only being directed to single spinal problems which overcome previous reduction device, comprehensive a variety for the treatment of means, default
It detects and realizes intelligent therapeutic under the monitoring of program.Simultaneously as in view of the same presentation of user is that may be present a variety of pathogenic
Mechanism, the detection being combined using a variety of detection means, decision logic are allowed the devices to voluntarily according to the specific feelings of user
Condition makes appropriate physical therapy.To realize backbone reduction, rehabilitation effectively, safe, unnecessary secondary damage or delay are avoided.
The reduction device that the present invention refers to include checking with EMG method module 1, magnetic therapy module 2, supporting module 3, control module 4,
Display module 5 and ECG module 6 etc..
The present invention relates to electro physiology and electromagnetism medical domains.Myoelectricity (EMG) signal known to us, amplitude, frequency spectrum
With own characteristic:The surface EMG signal measured from body surface is usually very faint, and amplitude is usually no more than 5mV;Frequency also compares
Relatively low, spectral range is generally 0.02-1000Hz, and spectrum energy is concentrated mainly between 0.25~350Hz.The relaxation of muscle and
There are good linear relationships between tensity and generation surface myoelectric voltage amplitude.It is square to measure myoelectricity voltage magnitude use
Root method can not only reflect the variation characteristic of EMG signal amplitude on time dimension, but also depend on muscle load sexual factor and muscle
Inner link between physiology itself, biochemical process, therefore, which is commonly used in real time, with no damage
Reflect muscle activity state, there is preferable real-time.Meanwhile the impedance of human muscle part can effectively state human body and loosen
Degree, in general human body are more loosened, and impedance is smaller.Therefore human body flesh can in real time, accurately be obtained using the above method by combining
Meat tensity, and it is classified.
Obtained muscle tonue degree may include much information, for example bone injury caused by backbone strain, hyperplasia etc., lactic acid
Pain caused by metabolism disorder and muscle cramp, and muscular tone etc. caused by external force or psychology.If cannot have
Effect, which is distinguished, leads to myotonic different reasons, then cannot effectively carry out immunotherapy targeted autoantibody.The present invention passes through in body surface specific region
Setting electromyographic signal acquisition device obtains the real-time myoelectricity of human body, impedance signal, at the same by can real-time live programming gate control logic
Preset program in circuit realizes identification and classification for above-mentioned electromyography signal exception inducement, and according to different judging results
To carry out the combination of different treatment means.
First, transcranial magnetic stimulation (TMS) first is implemented to user, selected stimulated zone is located at Epidural cavity, is lured by magnetic field
Send out potentiometric detection.Simple magnetic stimulator is by DC power supply, charging circuit, energy-storage travelling wave tube, discharge switch, charge-discharge control circuit
With a few part compositions such as coil.Various transcranial magnetic stimulation instruments well known to those skilled in the art and the control dress including software
Set and the present invention be introduced by reference, for example, DTMS transcranial magnetic stimulations circuit device described in US2008200749A or
The U.S.'s Medtronic Mag Pro type magnetic stimulators being commercialized.
Using the excitement that Neural stem cell cortical motor area generates, spinal cord anterior horn cell or surrounding god are made by downlink conduction path
It is depolarized through motor fiber, is Motion Evoked Potential detection thorn in the potential change that respective muscle, nerve, spinal cord are recorded
Swash.According to different stimulus modalities, SRPs can be divided into sensory evoked potential (somatosensory evoked potential,
) and Motion Evoked Potential (motion evoked potential, MEP) SEP.SEP mainly reflects the conduction of spinal cord back side uplink
Feel the function status of access, and the MEP stimulated through cranium then reflects the integrality of ventral side of spinal cord downward movement conduction path.By
MEP helps to detect whether backbone has substantive damage, has particularly with the latent lesion for not embodying apparent physical handicaps
There is preferable flaw detection effect.MEP can be divided into Spinal motor evoked potentials (SCMEP), nervimotion Evoked ptential (MEP-N) and flesh
Meat Motion Evoked Potential (MMEP) may be used as human body different parts neurotrosis detection and is used respectively.Maerten, Dvorak
Et al. research point out that in vertebral disease and the protrusion of the intervertebral disc, the sensibility of MEP is 84%, 36% compared with SEP obviously increases
Height, and MEP is slightly above lumbar spinal stenosis to the sensibility of spinal canal stenosis.Supposition is small with cervical spinal canal, is more easy to after narrow
It oppresses caused by spinal cord.It is 85% that Machida, which has then reported the sensibility through cranium MEP Spinal Cord Injury of Trauma patients,.In order to logical
It crosses skull and scalp etc. and reaches stimulation location, make peak magnetic field not be smaller than 1 spy by the selection of coil turn and current value
Si La (T), generally should be between 1-2T.Tablet circular coil (its is arranged in tangentially relationship therewith at the top of user's skull
Field stimulation is larger, is more suitable for peripheral nerve), can be ironcore choke or built-up coil, coil diameter 12-20 centimetres it
Between, hub of a spool is less than 3.5 centimetres away from user crown distance.Because being used only for physiological detection, therefore action time is short, using certainly
Right cooling or air cooling way.Via the coil, 1-3 centimetres of depth realizes fast frequency TMS in user's skull, also immediately
The time-varying magnetic field frequency that time-dependent current generates is more than 1Hz.It can be realized using common motor potential detector for being pierced through cranium magnetic
The detection for swashing MEP signals, visits spinal cord conduction path by analyzing the conventional indexs such as its conduction time and signal magnitude
Wound.Such situation should strictly forbid the mechanical massage for affected part or region of interest, avoid subsequently massaging step for vertebra production
Raw secondary damage.
Secondly, periphery Nervous pathway can be also detected by MEP.The acquisition methods of the MEP of peripheral nerve with
Existing SEP technologies are similar, by the way that the anode of patch leading electrode is arranged in targeted muscles abdomen to be measured, and in neural downlink tendon section
Cathode is set, it is ensured that distance is on 35mm between electrode.Subcutaneous microneedle electrodes can be used instead when necessary and improve picking up signal effect
Fruit and avoid noise jamming.It can be stated simultaneously according to patient master, carrying out MEP signals in specific limbs nerve pathway or neuromere picks up
It takes, and then targetedly pays close attention to the myoelectricity wave conducted via specific spinal levels, can exist to specific nerve pathway and damage
Wound carries out observational measurement.The selection of the targeted muscles is with the conventional selection standard of this field transcranial magnetic stimulation signal detection
Can, in principle to be preferred at the four limbs major muscles far from trunk, it is not limited to wherein.
In the detected waveform signals of MEP, the first single-phase positive phase wave quickly reached is known as ground wave (D waves),
Because its conduction is transmitted without cynapse, so also referred to as ground wave;And occur one group of positive wave (I waves) after D waves, it is contact
Caused by fiber indirect excitation pyramidal cell, referred to as indirect wave.Electro photoluminescence draws MEP waveforms and prompts spinal cord conduction beam function normal,
And waveform disappearance shows that conduction function blocks, i.e. " all or none " or the decision principle of decreased amplitude 80%, monitoring is sensitive
Degree is up to 100%.If there is D wave blocks, classification will be made by gating circuit, mechanical massage is forbidden to carry out, anti-major structure
It is injured at treatment.And it is normal in the conduction of D waves, and I wave incubation periods lengthen (criterion is substantially between 2.5-5 times of ordinary duration)
Imply that there are inflammation damnifications, such as overwork etc. to lead to demyelinate symptom.Clinical trial shows in patient without anesthesia waking state
Under, above transcranial magnetic stimulation, which can be simulated effectively, twice in succession stimulates out normal induction signal.Appropriate mechanical massage is aided with magnetic
The myoelectricity induced stimulation contributes to enlivening for neuron and conduction path.
Finally, checking with EMG method module further includes the pick device for myoelectricity (such as surface electromyogram signal), to detect
Neuroelectricity conducting power.Terminate in MEP detections, judging patient, there is no spinal cord, neurotrosises etc. not to be suitable for mechanical massage
After disease, myoelectricity pick device detects the electromyography signal of the specific massage part of patient in real time.Muscle occur pain, spasm or
When simple fatigue problem, problem (including pain point, spasm point and tired area etc., the same below) peripheral nerve fiber conduction speed
Degree slows down, poor blood circulation, this also complies with general cognition.It can be obtained by the detection of electromyography signal and be made further
It distinguishes.
Recent kinematics research shows that:Human skeletal muscle's slow switch fibers is more, and area percentage is bigger, the frequency of electromyography signal
MPF descending slopes are slower in domain analysis index.Further, pain especially chronic long pain can cause local muscle fast
Muscle fibre accounting and volume increase and slow switch fibers is accordingly weakened, and are significantly increased so as to cause MPF value descending slopes.For example,
Clinical discovery teres minor pathological inflammatory or non-pathologic spasm can cause dorsal root ganglia frequency of spontaneous discharges to increase
Add, radial pain as a result may be generated at corresponding side root pain and upper limb.Problem --- phase around painful area
The generation of high frequency electrical signal can be had by closing nerve fiber, be presented as median frequency dramatic decrease namely median frequency slope
(median frequency slope, MPs) increases apparent.Inventor thinks the height occurred during this nerve fibers conduct
The quick interruption phenomenon of frequency, is a kind of adaptive phenomenon of human body under incomplete block.The high frequency intermittent phenomenon of problem electric signal,
So that organ-tissue peripheral cell charge quickly changes between increasing and reducing.This high frequency flash is both that a kind of physiology refers to
Mark, also can be used as it is a kind of stimulation, treatment means exist.
And in the aching pain of muscles that sports fatigue generates, it is emerging to maintain muscle tone to strengthen motor unit when due to fatigue
The synchronism put forth energy;And intramuscular pressure increases the sarolemma surexcitation that caused blood flow is obstructed with lactic acid accumulation generation, to lead
Muscle fiber conduction velocity is caused to reduce (muscle fiber conduction velocity), it can be in this fatigue after exercise
As dominant index.It may be implemented myoelectric amplitude and slowly increased by massage, physical therapy, the frequency of average power of electromyography signal
(median power frequency, MPF) is also raised simultaneously, it is understood that it is rested for fast muscle fiber, lactic acid metabolism
Restore normal with problem blood circulation.
The electrode sample frequency for detecting pain signal is 300Hz-500Hz, preferably 450Hz;Tired signal detection electrode
Setting sample frequency is 8-300Hz, preferably 20-100Hz, more preferably 50Hz.Common-mode rejection ratio is more than 120dB, sensitivity 1
μV.Pickoff electrode measures fleshy exterior face electrical activity using active surface electrode, and conduction region diameter is between 6-12mm.Electrode selects stone
Electrode ink or Ti electrode, prevent it from accident occurring in magnetic field.
Patient's readme affected part is smeared using skin temperature allochroic paint before placing electrode and extends smearing, the Pi Wenbian to backbone side
Color coating can effectively identify body surface temp different, muscular tone, spasm etc. influence blood circulation position and around and it is strong
Side forms sharp contrast.The skin temperature allochroic paint uses the binary mixture of two kinds of palmityl alcohol, myristyl alcohol organic matters to be molten
Agent is allowed to color change interval between substantially 30-44 degrees Celsius by adjusting the two with when processing technology, further in
Between 33-40 degrees Celsius.Above-mentioned there is the low temperature point significantly lower than strong side and peripheral part to make label.
Every group of three electrodes are arranged centered on the mark point, and active, measuring electrode line is parallel at mark point
Main muscle fibre trend, electrode long axis itself and muscle fibre are in the same direction, spacing 2-2.5cm, and avoid being positioned on tendon as possible, in
Property electrode be placed on above-mentioned mark point nearby voltage-neutral location.Strong side is symmetrically chosen, and one group of electrode is equally arranged.
It is connected with electromyography signal in-situ processing device after electromyography signal pick device, is patrolled after realizing filtering, amplification
It collects and judges, if the signal obtained in low-frequency sampling sequential enters tired signal and judges process;If in high frequency sampling time sequence
The signal inside obtained then judges process into pain signal.In above-mentioned electromyography signal judgement process, realize that fast Flourier becomes
Its MPF value is got in return, to carry out frequency-domain analysis.Whether met using Matalab analyzers monitoring MPF values during frequency-domain analysis
, for example there is rapid decrease in pre-set level or even flash (similar cliff of displacement formula declines) phenomenon then indicates that it enters alleviation pattern 2-1,
Otherwise enter relaxed mode 2-2;Adaptive neural network mode of learning can also be used to judge, Binding experiment number of chambers evidence obtains
To natural spine both sides myoelectricity distribution map, add for different heights, age, weight or even Anthropometric parameters setting human region myoelectricity
Weight coefficient table judges after Ipsilateral myoelectricity data/strong side data is more than weighting coefficient.
The working procedure of control module is carried out according to lower row logic during above-mentioned picking up signal:Detect transcranial magnetic stimulation
Targeted muscles generate MEP signals, judge neural downlink conductive link with the presence or absence of damage, be embodied in D waves whether by
It is correctly detecting;Then strictly forbid any type of mechanical massage if there is link conductive impairment;If MEP signals normally if
Into real-time table facial muscle pyroelectric monitor process, mainly whether there is rapid decrease or even sudden strain of a muscle by MPF values in monitoring signals among these
Disconnected phenomenon come determine enter which kind of massage mode, also can further combined with MPs signals and monitor electromyography signal latent time.
In alleviating pattern 2-1, apply magnetostatic field, (or left and right) direction is arranged above and below massage bed in size 0.6-0.9T;
Backbone side, which is traced back, in skin temperature indicating positions applies ultrasound, the ultrasound convergence depth 0.8-2.5cm, frequency 0.2-1.0MHz, work(
Rate 1mW/cm2;Ultrasonic transducer used is close to skin, transducer probe effective area 10mm × 8mm, longitudinally perpendicular in human body ridge
Column direction.Ultrasound corresponds at substantially neuromere the convergent point for forming 1 square centimeter area, nerve fiber at this in subcutaneous tissue
Middle cell wall can be vibrated with intracytoplasmic charged particle, lead to cell membrane depolarization according to Hall effect.Action electricity
Position will be conducted to corresponding skeletal muscle, cause slightly to twitch or tremble.This action potential is sent out by autologous patient neurode, tool
There are altitude simulation and adaptability, induction to obtain its size of action potential and supersonic frequency nonlinear correlation.At the same time, aforementioned
Supersonic frequency size makes adaptive change with the electromyography signal that aforementioned pickoff electrode obtains, which makes myoelectricity
MPF drop-out values reduce.Because of " logical or nothing " characteristic of multiple neuron membrane depolarizations, clinically it is observed that above-mentioned induction
The non-linear increase of current potential namely its be likely to occur do not follow supersonic frequency adjust and the phenomenon that linear change.Control module pair
The adjusting of supersonic frequency is carried out as unit of 0.1KHz, and the supersonic frequency adjusted every time is kept at least one period or more, in week
Period is every the above-mentioned MPF values of detection.
In relaxed mode 2-2, apply magnetostatic field (avoiding acting on user head), size 2.5T can massaged
Bed (or left and right) direction setting up and down;Then select temperature change most visibility point as gradient magnetic according to the instruction of above-mentioned skin temperature
Field action band center, applies gradient magnetic, size 100mT, switching rate 10-15mT/m.s (y circles).Under its effect, on
It is imperceptible random to which naked eyes occur to state tissue generation bioelectrical effect of the zone of action including nerve, muscle receptors
Then belly of muscle is shaken, and contributes to blood circulation and lactic acid metabolism, while generating more or less according to gradient magnetic switching rate difference
Heat.The heat of generation will cause the part for being coated with skin temperature allochroic paint that temperature change occurs, and reach phase wherein included
Phase-change material will be caused to absorb heat liquefaction after becoming material threshold, to avoid skin thermal damage.Meanwhile operator can pass through
The color of skin temperature allochroic paint monitors skin temperature.In the dwelling period of gradient magnetic, myoelectricity acquisition module is started to work the period
When, above-mentioned phase-change material will also have an effect too low to avoid coated portion temperature, prevent skin, muscle due to cold and hot change
Muscle tonue causes electromyography signal error caused by changing.
Electrocardiogram large sample analysis for different parting cervical spondylosis patients is the result shows that cervical spondylosis and electrocardiographic abnormality
With larger correlation or even homogeneity, therefore the neck heart syndrome that is otherwise known as.In the process for carrying out magnetic stimulation to peripheral nerve
The bioelectricity of middle generation inevitably will partly overlap or even conflict with electrocardiosignal.Clinical data shows such case
Particularly evident in patient with cervical Spondylopathy, the error burst of ultrasonic magnetic field therapeutic effect will significantly increase.If can be further
Ground increases heart real time detection in the above-mentioned magnetic therapy module course of work, it will is cut for ultrasonic magnetic therapy and provides better opportunity and refer to
Show.
Huo Dun (Holden) 2004 research shows that vascular wall in magnetostatic field can in body surface generate a potential difference,
The induction field may influence propagation (the The sensitivity of the heart to static of electrocardio action potential
magnetic fields【J】.Progress in Biophysics&Molecular Biology, 2005,87 (2-3):289_
320.).For the ECG detectings results such as three existing frequently-used leads, five leads, 12 lead, magnetostatic field induced electricity
The influence of gesture is mainly reflected in the deformation of T waves or delay.Magnetostatic field is treated in alleviation pattern 2-1 for example of the present invention, because of magnetic field
Intensity is smaller to be not enough to significantly affect electrocardio generation, but by detection and experimental result comparison still it can be seen that similar
Interference of the bad potential difference for therapeutic effect.In order to avoid interference can be electrocardiogram equipment add reliable ground, filter and
Metal casing etc..Further, electrocardiosignal can be made to realize the ultrasound in S waves triggering pattern 2-1 by circuit.
And during the field variation of relaxed mode 2-2, the detection of electrocardiosignal tends to occur serious distortion, so such as
What realizes the technical issues of better magnetic therapy incision opportunity would be further desirable to solve.It is carried out in Hebei Normal University《Abdomen
Formula is breathed for Heart rate influences》It is being obtained in experiment statistics indicate that it is subjective control abdominal respiration rhythm contribute to control heart rate
In a relatively low and stable level.The correlative study of same Xi'an Communications University also indicates that heart rate and breathing can be accomplished
Interaction, this will not be repeated here for coupled relation.In the present invention, lower heart rate is bioelectric to peripheral nerve dry for avoiding
It is apparent advantageous to disturb;Can there are an obvious loosening stage, the rank in the end of breath respiratory muscle of abdominal respiration simultaneously
Section can reach 6-8 seconds by the conscious extension of user.The gradient magnetic switching rate in control 2-2 massaging ways is at this time
Peak value will obtain better effect.Therefore breathing instruction device is further arranged in the present invention, uses the acousto-optic of any prior art
Electricity etc. prompts means, such as buzzer or LED flash decorations.It is used to indicate the frequency that user carries out abdominal respiration, together
When user enter steady respiratory state after coordinate gradient magnetic variation, make the expiration of magnetic field switching frequency and abdominal respiration
Stage keeps synchronizing.Clinical trial shows that most of adults can keep when cooperation breathing instruction device carries out abdominal respiration
5-7 times per minute respiratory rate, while the relatively low heart rate level that heart rate will drop in its normal range (NR).Combined magnetic field is controlled at this time
Therapeutic effect is significantly increased, and in the case for the treatment of time is isometric, the MPF values measured can be differed with respect to 1%-10% is risen.
Again further, increase drug adjuvant treatment effect in above-mentioned reduction system work process, by medication mould
Block is realized, it is therefore intended that is promoted local location blood flow, is improved the remission effect of muscular tone.The drug uses this field
Psoralen known to technical staff, promoting blood circulation proved recipe increase and decrease, are mixed into aforementioned after further grinding active ingredient after boiling purifies
It is coated on the position for receiving magnetic therapy in skin temperature allochroic paint.Skin is penetrated into after the process said medicine of Neural stem cell is heated to realize
Drug effect.
Specific implementation mode
Backbone reduction system includes the physical therapy rack 31 as carrying user, which is equipped with corresponding to number of people face
Opening breathes convenient for user's prostrate.Rack uses non-metallic material, avoids influencing electromagnetic curing therapeutic effect, and lower section is equipped with four
The support post of band idler wheel.It is equipped with cyclic annular fence 32 around the rack 31, there is activity in corresponding user foot fence
Railing, whole fence are in the openable and closable shape of the mouth as one speaks in one end.User's head position is corresponded in fence 32 and is equipped with support arm 321, is being enclosed
Column side corresponds to the support arm 322 that user's trunk is equipped with more or more.The support arm can be with multi-angle rotary, bending simultaneously
And it can be slided on fence to adapt to different location.Support arm material is using nonmetallic, and its end is equipped with fixed seat 323.
Ultrasonic probe, infrared probe, gradient magnetic field coil etc. are detachably connected in the fixed seat of above-mentioned support arm.On a fence left side
Side is equipped with magnetostatic field generator 324, provides magnetostatic field referring now to user's metastomium on rack 31 in fact.Size is specially
0.6-0.9T is realized by steady controllable current, and the various common techniques in this field can be used.In enclosing for corresponding user's head position
It is equipped with magnetic shield panel 325 at column, uses the ferromagnetic material that magnetic conductivity is high, such as be made can be along the screen of fence slidable adjustment for silicon steel
Shield plate, thickness is between 1-5mm.Foldable lid is overlying on user head effectively to avoid user's head after sliding into appropriate location
Portion receives unnecessary magnetic stimulation.
It is removably fixed with tablet circle or splayed coil 21 in the fixed seat of above-mentioned support arm 321, can be iron
Wire-core coil or built-up coil.Coil diameter is between 9-20cm, preferably 12-15cm, and the peak magnetic field of generation is not less than 1T.It is passing through
Hub of a spool is made to be less than 3.5cm away from user crown distance by adjusting support arm during cranium Neural stem cell.Changing currents with time produces
Raw field frequency is more than 1Hz, and the winding wire is connected to control device by the fixed seat on support arm 321.
Anode electrode 11 is arranged in the transcranial magnetic stimulation stage at user back or upper limb targeted muscles belly of muscle, at neural downlink tendon
Cathode electrode 12 is set.Electrode uses graphite electrode, between the two away from 35mm or more.The above-mentioned collected signal of two electrodes is sent to
Control device is analyzed after filtered shaping amplification:There is retardance in the first single-phase positive D waves received to control
Device carries out alarm, reminds the operator user that cannot carry out any type of mechanical massage and stops further warp
Cranium Neural stem cell carries out;It is normal in D waves, and there is delay and are more than in the case of 2.5 times of ordinary duration in subsequent one group of positive I waves, warp
Cranium Neural stem cell be normally carried out a cycle or detection I wave incubation periods shorten after stop.A cycle can be recognized by control device
To input, generally between 120s-600s.
The selection of above-mentioned targeted muscles can be according to user's readme, after can also being observed using skin temperature allochroic paint
It carries out.Specific practice is:It is raw material to choose palmityl alcohol, myristyl alcohol, procrypsis agent and color developing agent, and wherein procrypsis agent can choose temperature-sensitive
Dye crystallization violet lactone CVL, color developing agent choose diphenol propane BPA, and two kinds of alcohol exist as solvent and proportioning object.By solvent and
Solute, which is poured into the container of heating water bath to stir enough one hour, obtains compound.Its discoloration depends on the matter of four kinds of substances
Ratio is measured, when CVL: BPA: myristyl alcohol: for the mass ratio of palmityl alcohol at 1: 3.3: 41: 22, compound fusing point is minimum, and
There is good discoloration between 33-40 degrees Celsius.Above-mentioned compound is uniformly mixed with common phase-change material, phase-change material
Paraffin etc. can be chosen, by simply matching processing so that its phase transition temperature is at 40 degree or so.Mixed phase-change material and upper
It states compound and is coated on user's readme affected part and strong side corresponding position.Whether there is or not the discolorations of apparent skin temperature for observation after parked 3 minutes
Phenomenon is marked with surrounding skin significant difference or with the visibly different position in strong side.
Surface electromyogram signal pickoff electrode is set centered on mark point, and one group of three wherein neutral electrode of electrode 13 is put
Set in the voltage-neutral location nearest away from mark point, active measuring electrode then ensure its line it is parallel with mark point at main muscle fibre
Trend, electrode long axis itself and muscle fibre are in the same direction, and two electrodes should avoid being positioned on tendon at this time at a distance of 2-2.5cm.Strong
The same symmetrically placed one group of electrode 14 in side.The electrode sample frequency for detecting pain signal is 300Hz-500Hz, preferably 450Hz;
Tired signal detection electrode setting sample frequency is 8-300Hz, preferably 20-100Hz, more preferably 50Hz.Common-mode rejection ratio
More than 120dB, 1 μ V of sensitivity.Pickoff electrode measures fleshy exterior face electrical activity using active surface electrode, and conduction region diameter is in 6-
Between 12mm.Electrode selects graphite electrode or Ti electrode.
The conducting wire drawn from two arrays of electrodes is respectively by realizing that Fast Fourier Transform obtains its MPF value after filter and amplification.
Thereafter two groups of data respectively enter the logic judgment unit 41 of control device.The Ipsilateral signal obtained in high frequency sampling time sequence into
Enter pain signal and judges process, and the Ipsilateral signal obtained in low-frequency sampling sequential enters low frequency and judges process.In each judgement
The Matalab analyzers 42 of control device carry out frequency-domain analysis to it in process, first determine whether to obtain in high frequency sampling time sequence
MPF values are whether there is or not there is rapid decrease or flash phenomenon, and whether there is or not apparent to weigh the corresponding median frequency slope (MPs) for criterion
It increases, slope value normal range (NR) should make induction signal with reference to user's age, body fat, weight and strong side default, also may be used
By carrying out adaptive learning acquisition to user's many experiments.The general MPs values are more than or equal to 60% i.e. it is believed that user
Affected part muscle need carry out physical therapy alleviation, into process 2-1.If the MPF values obtained in high frequency sampling time sequence do not occur
The case where above-mentioned rapid decrease, the MPF values that further analysis affected part low-frequency sampling obtains of analyzer 42, and also according to above-mentioned step
Suddenly analysis comparison is carried out.MPs values are more than 45% and the latent time of collected electromyography signal are combined to may determine that use at this time
Person needs progress physical therapy to loosen, into process 2-2.
In pattern 2-1, control device starts magnetostatic field generator 324 and applies magnetostatic field, and size 0.6-0.9T's is magnetostatic
Field is applied at user's trunk, especially backbone;Setting region of insonation at the 5-10cm of backbone side is traced back in mark point;It is logical
It crosses ultrasonic probe and applies ultrasound, ultrasound convergence the depth 0.8-2.5cm, frequency 0.3-1.0MHz, power 1mW/cm2;It is used
The energy converter of ultrasonic probe is close to skin, energy converter effective area 10mm × 8mm, longitudinally perpendicular in human spine direction.Ultrasound
Correspond to the convergent point that 1 square centimeter area is formed substantially at neuromere in subcutaneous tissue, at this in nerve fiber cell wall with
Intracytoplasmic charged particle can vibrate, and lead to cell membrane depolarization according to Hall effect.Action potential will conduct
To corresponding skeletal muscle, cause slightly to twitch or tremble.At the same time, aforementioned.Supersonic frequency size is obtained with aforementioned pickoff electrode
Electromyography signal make adaptive change, which makes the MPF drop-out values of myoelectricity reduce or in other words so that MPs values
" raising ".The a cycle that often works control device stops magnetic field function, into surface electromyogram signal acquisition sequential.Operating mode 2-
Enter high frequency sampling time sequence after 1, the skin surface electromyography signal of pickup repeats the above steps again.Until the MPF that measures or
MPs values reach preset standard.
In pattern 2-2, apply magnetostatic field (avoiding acting on user head), size 2.5T can be on a massage bed left side
Right direction is arranged;Then select temperature change most visibility point as in Actions of Gradient Magnetic Field band according to the instruction of above-mentioned skin temperature
The heart applies gradient fields, size 100mT, switching rate 10-15mT/m.s (y circles).Gradient coil setting aforementioned support arm it
On one.
Under the Actions of Gradient Magnetic Field, bioelectricity occurs for tissue of the above-mentioned zone of action including nerve, muscle receptors
Effect to by naked eyes it is imperceptible it is random in the form of realize belly of muscle shake.Clinical trial show this promoting blood circulation and
It additionally aids the fatigue recovery of corresponding nerve pathway after lactic acid metabolism, while generating according to gradient magnetic switching rate difference or more
Or few heat.The heat of generation will cause the part for being coated with skin temperature allochroic paint that temperature change occurs, and wherein include reaching
Phase-change material threshold value after will cause phase-change material absorb heat liquefaction, to avoid skin thermal damage.Meanwhile operator can be with
Skin temperature is monitored by the color of skin temperature allochroic paint.In the dwelling period of gradient magnetic, myoelectricity acquisition module is started to work
When the period, above-mentioned phase-change material will also undergo phase transition release heat it is too low to avoid coated portion temperature, prevent skin, flesh
Meat causes electromyography signal error due to muscle tonue caused by cold and hot variation.Gradient magnetic switching rate size is obtained with aforementioned pickoff electrode
To electromyography signal make adaptive change, which makes the MPF drop-out values of myoelectricity reduce or in other words so that MPs values
" raising ".The a cycle that often works control device stops magnetic field function, into surface electromyogram signal acquisition sequential.The difference is that work
Enter low-frequency sampling sequential after operation mode 2-2, the signal of pickup repeats the above steps again, until MPF or MPs values reach pre-
Bidding is accurate.
The wherein described gradient magnetic field coil on aforementioned support arm holders by being arranged figure-eight coil, the coil upper half
A 0 is fixed in fixed seat, and lower half 0 setting is below aforementioned rack.Upper lower coil is opposite to be constituted, and entire coil can follow
Support arm is moved forward and backward to adapt to the variation of different location.
Infrared skin temperature monitoring probe can further be added to prevent scald.The infrared radiation thermometer uses
This field common technique can be realized, and monitoring range is between 30-45 degrees Celsius.Its detecting head is solid mounted on aforementioned support arm
In reservation, it is electrically connected with control device.By presetting early warning temperature in control device, such as 41 degrees Celsius (need to consider herein
The specific selection of phase-change material), to realize the temperature pre-warning for monitoring area, prevent scald or unexpected generation.
Further in order to avoid in pattern 2-1 magnetostatic field generate the mutual of electric potential field and electrocardio action potential in vascular wall
It influences, may be used and introduce electrocardioscanner 61.It, which uses the modes such as three common leads, five leads or 12 lead to detect, makes
User's electrocardio.In order to avoid interference using the modes such as reliable ground, filter and outer cover metal-coating to electrocardioscanner 61 into
Row protection.The startup of electrocardio S waves triggering ultrasound can also be realized using detection trigger circuit.Namely increase on electrocardioscanner
If related circuit:ECG signal sampling circuit 62 realizes the amplification to electrocardiosignal, and signal band can in 1-2KHz, amplification factor
With adjustment;S waves detecting circuit 63 is made of follower, QRS filters, whole wave circuit, peak-holding circuit and comparator.Electrocardio
Figure output signal, which is converted to be input in monostable flipflop after the whole wave of voltage signal, detects S waves, and obtains S wave lock-out pulses
Signal.Driving circuit is triggered in the rising edge of S waves, realizes the startup for ultrasonic signal.Evaded out based on the trigger circuit
The R waves of heart action potential act on, influencing each other both to reduce.Further, trigger circuit is not direct and starts
Circuit is connected and is connect with start-up circuit by control module.At this time after obtaining rising edge trigger signal, control module should
Signal is temporary, just starts ultrasonic signal after obtaining next trigger signal;Above-mentioned temporary behavior can effectively reduce periphery god
The refractory period of warp is reacted, and treatment effective time is increased.According to actual effect, temporary two or more triggerings also can be further set
Driving ultrasound circuitry of just awaiting a favorable opportunity after signal works.
Further in order to realize that better magnetic therapy cuts opportunity problem in pattern 2-2.In fence close to user
Head position adds a buzzer or similar warning means.The buzzer is electrically connected control device and by its management, for instructing
User carries out the frequency of abdominal respiration, while coordinating the variation of gradient magnetic after user enters steady respiratory state, makes
Magnetic field switching frequency is synchronous with the holding of the expiration phase of abdominal respiration.Specifically buzzer, which sounds, prompts user's air-breathing, control
Device processed controlled between buzzer sounds 3s-6s gradient magnetic field coil switching rate be at least held in its peak value 80% it
On.Clinical trial shows that most of adults can keep 5-7 times per minute when cooperation breathing instruction device carries out abdominal respiration
Respiratory rate, while the relatively low heart rate level that heart rate will drop in its normal range (NR).Combined magnetic field therapeutic effect has aobvious at this time
It writes and improves, in the case for the treatment of time is isometric, the MPF values measured can be differed with respect to 1%-10% is risen.
Again further, increase drug adjuvant treatment effect in above-mentioned reduction system work process, by medication mould
Block is realized, it is therefore intended that is promoted local location blood flow, is improved the remission effect of muscular tone.The drug uses this field
Psoralen known to technical staff, promoting blood circulation proved recipe increase and decrease, are mixed into aforementioned after further grinding active ingredient after boiling purifies
It is coated on the position for receiving magnetic therapy in skin temperature allochroic paint.Skin is penetrated into after the process said medicine of Neural stem cell is heated to realize
Drug effect.Specific drug component is following (mass ratio):Herba Epimedii 5, the rhizome of davallia 21, the root of bidentate achyranthes 6, safflower 1, windproof 9, Moschus 1, mountain paint 2,
Dragon's blood 11, psoralea corylifolia 3, amber 4, Rhizoma Chuanxiong 10, Rhizoma Et Radix Notopterygii 2.The drug ingedient also can be individually coated with after removing skin temperature allochroic paint
In affected part, temperature monitoring is completed by aforementioned infrared probe completely at this time.Also aerogel dressing cooperation can be added during use;
Even spread said medicine coating in medical aseptic transparent aquagel dressing layer;It is specific shape to cut out dressing layer, is laid in ridge
Column both sides main muscle group, such as erector spinae, multifidus etc. are not limited to specific magnetic therapy position;Need cooperation corresponding after coating simultaneously
The mechanical stretch effect of muscle group is realized by adding upper limb mechanical stretch bar;The stayed pole is set to massage platform user
Head side, height are slightly above the user back of prostrate;Direction of draw is parallel to the platform, and force direction is far from human body
To realize the drawing to user's upper limb;Drawing is controlled by control module, and frequency is between 5-15 times per minute.Further
, drawing can be matched with abdominal respiration frequency.Specifically, buzzer sounds after prompt user breathes and pulls, and leads
Pull and support it is 4-8 seconds continuous after loosen;User is disappeared using traction force to be indicated as exhaling.
Foregoing control device can use the common microcontroller in this field, field-programmable to gate the realizations such as circuit or microcomputer,
With the use of keypad or conventional keypad as input unit.
Above-described embodiment is used as just technical solution of the present invention explanation, and restriction should not be used as to understand that its protects model
It encloses.Those skilled in the art on the basis of the present invention done any improvement for not departing from present inventive concept or remodeling without departure from this
Invention protection domain.
Claims (2)
1. a kind of medication coat applied to backbone reduction system forms, the backbone reduction system includes:
Checking with EMG method module 1, magnetic field module 2, massage module 3, control module 4, display module 5 and ECG module 6 etc.;Wherein
The checking with EMG method module detects human body surface myoelectric in real time, and is classified according to myoelectricity level and feature, the classification knot
Fruit can be tight to muscle caused by muscle tonue caused by user's bone injury, lactic acid metabolism imbalance and spasm and external force or psychology
Etc. distinguish;The control module enters default alleviation massage mode 2- according to the classification results that checking with EMG method module is sent
1 or relaxing massage pattern 2-2;
It is characterized in that:Increase drug adjuvant treatment effect in above-mentioned reduction system work process;The specific drug of drug
The following mass ratio of component:Herba Epimedii 5, the rhizome of davallia 21, the root of bidentate achyranthes 6, safflower 1, windproof 9, Moschus 1, mountain paint 2, dragon's blood 11, psoralea corylifolia 3,
Amber 4, Rhizoma Chuanxiong 10, Rhizoma Et Radix Notopterygii 2;Active ingredient is placed in mortar grinder after boiling, filtering purification and is further ground, it
It is mixed into skin temperature allochroic paint afterwards and is coated on the position for receiving magnetic therapy;Skin is penetrated into after the process said medicine of Neural stem cell is heated
Realize drug effect;The drug ingedient also can individually be coated on affected part after removing skin temperature allochroic paint, at this time temperature monitoring completely by
Additional infrared probe is completed.
2. medication coat forms according to claim 1, aerogel dressing cooperation is added during use;It is saturating in medical aseptic
Even spread said medicine coating in hydrous gel dressing layer;It is specific shape to cut out dressing layer, and it is main to be laid in backbone both sides
Muscle group, such as erector spinae, multifidus etc. are not limited to specific magnetic therapy position;The machinery for coordinating corresponding muscle group is needed after coating simultaneously
Effect is pulled, is realized by adding upper limb mechanical stretch bar;The stayed pole is set to massage platform user head side, high
Degree is slightly above the user back of prostrate;Direction of draw is parallel to the platform, and force direction is far from human body to realization pair
The drawing of user's upper limb;Drawing is controlled by control module, and frequency is between 5-15 times per minute, and further drawing can also coordinate
The frequency of user's abdominal respiration carries out.
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CN104587605A (en) * | 2015-01-11 | 2015-05-06 | 北京工业大学 | Electromyographic signal controlled peripheral magnetic stimulation system and method |
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EP3056244A1 (en) * | 2015-02-13 | 2016-08-17 | Nihon Kohden Corporation | Magnetic stimulation apparatus |
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