CN1068703A - 烧伤创面用鱼皮制备方法 - Google Patents

烧伤创面用鱼皮制备方法 Download PDF

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CN1068703A
CN1068703A CN 91105119 CN91105119A CN1068703A CN 1068703 A CN1068703 A CN 1068703A CN 91105119 CN91105119 CN 91105119 CN 91105119 A CN91105119 A CN 91105119A CN 1068703 A CN1068703 A CN 1068703A
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fish
skin
burn
borneol
ethanol
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王权海
孙银章
张广钦
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Abstract

烧伤创面用鱼皮敷料制作、保存方法。本发明是 将鱼剥取鱼皮后,浸置在由碘、酒精、冰片等化学物质 配成的溶液中处理、保存。该发明加工工艺极为简 单,无需添置特殊设备即能加工生产。用本方法制作 出的烧伤创面鱼皮敷料,成本低,携带使用方便,无副 作用,且治疗效果好,适用于烧伤、烫伤创面的敷用。

Description

本发明属于医学烧伤用生物敷料技术领域。
目前医学烧伤界在治疗烧伤(烫伤)所用的生物敷料较多,特别是目前使用猪皮作为烧伤创面敷料,其加工需要添置取猪皮机,还要配备一套特殊机械设备,加工工艺很复杂投资大,成本高,使用猪皮敷料覆盖创面后,容易导致创缘红痛,甚至有徊液外溢现象,患者较为痛苦。
本发明的目的是针对上述不足之处,提供一种新的烧伤创面用鱼皮的制备方法。
本发明的目的这样实现的:
在紧靠鱼头上缘切开鱼皮一周,任取一面,将具有一定硬度的呈椭圆状剥离杆从切口插入鱼皮与鱼肉之间左右移动至鱼的尾部,然后,另一面采用相同的方法,取下完整的鱼皮,将取下的鱼皮放入配比重量为碘酊0.014-0.02%、乙醇94-98%、冰片1-2%、磺胺嘧碇锌1-2%,另加盐酸调PH为2.5-3的溶液中灭菌保存;或者将鱼皮浸置在含有冰片的乙醇溶液中灭菌保存,保存鱼皮敷料溶液的最佳配比重量为碘酊0.016%、乙醇96.5%、冰片1.74%、磺胺嘧碇锌1.74%。含有冰片的乙醇溶液,最好乙醇的浓度为70-75%,乙醇与冰片的配比为20∶1-10∶1。如需携带时,还可以将鱼皮敷料放入带有保存溶液的塑料袋内,随时可提供使用。所取鱼皮的大小由鱼的大小决定。一般约8两重的鱼可取20×17厘米的鱼皮。取皮后的鱼照样可以食用,增加病员的营养。
本发明的优点:
本发明的制备简单,无需添置特殊设备,只需一些普通盛具和简单用具即能加工,条件差的单位也可以加工,且加工出的鱼皮敷料成本低,价格便宜,低于其它烧伤敷料,与猪皮敷料相比,价格低于猪皮敷料10倍。使用本发明加工出的鱼皮敷料,对创面排斥反应小,覆盖时间长,抗感染力强,能减少创面渗出,愈合快。对深Ⅱ度的创面不留疤痕,对体表慢性溃疡有一定效果。
以下介绍几个实施例:
实施例1:
取活鱼一条,在紧靠鱼头上缘切开鱼皮一周,任取鱼的一面,将呈椭圆状剥离杆插入切口内,操作剥离杆,在鱼皮与鱼肉之间左右移动至鱼的尾部,然后另一面采用相同的方法取下鱼皮,再将取下的鱼皮浸置在配比重量为碘酊0.016%,酒精96.5%,冰片1.74%,磺胺
Figure 911051198_IMG1
碇锌1.74%,另加盐酸调PH为2.5-3的溶液中常温灭菌、保存。
实施例2:
如实施例1所述的剥取鱼皮的方法取下鱼皮,再将取下的鱼皮浸置在配比重量为0.014%碘酊,酒精94%,冰片1%,磺胺嘧碇锌1%,另加盐酸,调PH值为2.5-3的溶液中,常温灭菌保存。
实施例3:
如实施例1所述的剥取鱼皮的方法,取下鱼皮,再将取下的鱼皮浸置在配比重量为碘酊0.02%,酒精98%,冰片2%,磺胺嘧碇锌2%,另加盐酸,调PH值为2.5-3的溶液中,常温灭菌保存。
实施例4:
如实施例1所述的方法取下鱼皮,再将取下的鱼皮浸置在浓度为70-75%的酒精加冰片的溶液中常温保存,无菌不变质。其酒精与冰片的配比为20∶1-10∶1。

Claims (3)

1、烧伤创面用鱼皮制备方法,其特征在于在紧靠鱼头上缘切开鱼皮一周,采用椭圆状剥离杆从切口插入鱼皮与鱼肉之间,剥下鱼皮,将鱼皮置于配比重量为碘酊0.014-0.02%、乙醇94-98%、冰片1-2%、磺胺嘧碇锌1-2%,另加盐酸调PH为2.5-3的溶液中灭菌保存;或将鱼皮置于含有冰片的乙醇中灭菌保存。
2、根据权利要求1所述的鱼皮的制备方法,其特征是所说的灭菌溶液的最佳配比重量为碘酊0.016%、乙醇96.5%、冰片1.74%、磺胺嘧碇锌1.74%,PH值2.5-3。
3、根据权利要求1所述的鱼皮的制备方法,其特征是所说的含有冰片的乙醇,其乙醇的浓度是70-75%、乙醇与冰片的配比是20∶1-10∶1。
CN 91105119 1991-07-25 1991-07-25 烧伤创面用鱼皮制备方法 Pending CN1068703A (zh)

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CN 91105119 CN1068703A (zh) 1991-07-25 1991-07-25 烧伤创面用鱼皮制备方法

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100400111C (zh) * 2006-10-27 2008-07-09 邯郸钢铁股份有限公司 医治烧伤用猪或牛膀胱膜性生物敷料的制备方法
WO2011042794A2 (en) 2009-10-07 2011-04-14 Kerecis Ehf A scaffold material for wound care and/or other tissue healing applications
WO2013144727A2 (en) 2012-03-30 2013-10-03 Kerecis Ehf A scaffold material graft for wound care and/or other tissue healing applications
WO2017035615A1 (pt) * 2015-09-03 2017-03-09 Companhia Energética Do Ceará - Coelce Processo de beneficiamento'da pele da tilápia e seu uso na cobertura de lesões cutâneas
WO2022201102A1 (en) 2021-03-24 2022-09-29 Kerecis Hf A colored biologic wound treatment providing healing progress monitoring
WO2024057291A1 (en) 2022-09-16 2024-03-21 Kerecis Hf Systems for making a fat-inclusive skin graft treatment composition, fat-inclusive skin graft treatment composition, and methods of making same

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100400111C (zh) * 2006-10-27 2008-07-09 邯郸钢铁股份有限公司 医治烧伤用猪或牛膀胱膜性生物敷料的制备方法
WO2011042794A2 (en) 2009-10-07 2011-04-14 Kerecis Ehf A scaffold material for wound care and/or other tissue healing applications
US8613957B2 (en) 2009-10-07 2013-12-24 Kerecis Ehf Scaffold material for wound care and/or other tissue healing applications
WO2013144727A2 (en) 2012-03-30 2013-10-03 Kerecis Ehf A scaffold material graft for wound care and/or other tissue healing applications
WO2017035615A1 (pt) * 2015-09-03 2017-03-09 Companhia Energética Do Ceará - Coelce Processo de beneficiamento'da pele da tilápia e seu uso na cobertura de lesões cutâneas
CN108778351A (zh) * 2015-09-03 2018-11-09 塞阿拉能源公司 用于改进罗非鱼皮的方法及其用于覆盖皮肤损伤的用途
US11135337B2 (en) * 2015-09-03 2021-10-05 Companhia Energética Do Ceará (Coelce) Tilapia skin processing method and use thereof for covering skin injuries
WO2022201102A1 (en) 2021-03-24 2022-09-29 Kerecis Hf A colored biologic wound treatment providing healing progress monitoring
WO2024057291A1 (en) 2022-09-16 2024-03-21 Kerecis Hf Systems for making a fat-inclusive skin graft treatment composition, fat-inclusive skin graft treatment composition, and methods of making same

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