CN106823100A - The simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading - Google Patents
The simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading Download PDFInfo
- Publication number
- CN106823100A CN106823100A CN201710082050.2A CN201710082050A CN106823100A CN 106823100 A CN106823100 A CN 106823100A CN 201710082050 A CN201710082050 A CN 201710082050A CN 106823100 A CN106823100 A CN 106823100A
- Authority
- CN
- China
- Prior art keywords
- cancer cell
- cell
- shunt pipe
- side opening
- preventing cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 34
- 201000011510 cancer Diseases 0.000 title claims abstract description 34
- 239000000839 emulsion Substances 0.000 claims description 3
- 239000002121 nanofiber Substances 0.000 claims description 3
- 210000000683 abdominal cavity Anatomy 0.000 abstract description 12
- 210000004027 cell Anatomy 0.000 description 43
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 28
- 210000004556 brain Anatomy 0.000 description 23
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 16
- 238000002513 implantation Methods 0.000 description 12
- 239000007788 liquid Substances 0.000 description 12
- 239000002775 capsule Substances 0.000 description 10
- 238000007912 intraperitoneal administration Methods 0.000 description 7
- 238000002347 injection Methods 0.000 description 6
- 239000007924 injection Substances 0.000 description 6
- 238000005086 pumping Methods 0.000 description 6
- 230000003187 abdominal effect Effects 0.000 description 4
- 238000009792 diffusion process Methods 0.000 description 3
- 239000013536 elastomeric material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 206010067484 Adverse reaction Diseases 0.000 description 2
- 206010022773 Intracranial pressure increased Diseases 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000006838 adverse reaction Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 201000009941 intracranial hypertension Diseases 0.000 description 2
- 238000000053 physical method Methods 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 238000007920 subcutaneous administration Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000005907 cancer growth Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000007917 intracranial administration Methods 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
- A61M25/0026—Multi-lumen catheters with stationary elements
- A61M25/003—Multi-lumen catheters with stationary elements characterized by features relating to least one lumen located at the distal part of the catheter, e.g. filters, plugs or valves
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses a kind of simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading, the isocon includes body, side opening and cell sieve, the body closed at both ends, symmetrical side opening is provided with the side wall at body both ends, and cell sieve is provided with body；The cell sieve is located between the side opening of both ends.Described isocon simple structure, it is reasonable in design；Cell sieve is the mesh-like structure of the 100nm of aperture 50, can effectively filter cancer cell, and encephalic cancer cell spreads to abdominal cavity after can effectively preventing ventriculoperitoneal shunt.
Description
Technical field
The invention belongs to technical field of medical equipment, and in particular to one kind physical method simply efficiently prevents cancer cell from expanding
Scattered Ventriculo peritoneal shunt pipe.
Background technology
Current Ventriculo peritoneal shunt pipe does not suppress the function of growth of cancer cells or diffusion, intracranial malignant tumor patient's ventricles of the brain
After peritoneal shunt operation a period of time, intracerebral cancer cell can be transferred to abdominal cavity, cause tumour to spread, and have a strong impact on patient vitals' peace
Entirely.
According to retrieval, the following several patent publication us related to present patent application are found：
1st, a kind of ventricles of the brain-abdominal cavity shunt device of cerebrospinal fluid (203970988U), the part flow arrangement includes that one is used to insert
The subcutaneous external water capsule of abdominal cavity of patients and one are used for the conduit of ICV drainage of cerebrospinal fluid to abdominal cavity, the outer wall of the conduit
On be arranged with an interior water pocket for extruded conduit, interior water pocket is connected by water injection pipe with external water capsule, and water injection pipe is provided with
The check valve of water pocket in for liquid in external water capsule to be introduced, the interior water pocket is provided with one for discharging liquid in its inner chamber
Liquid pumping hole, the liquid pumping hole by one be used for be pierced into liquid pumping needle silica gel sealing pad seal.The part flow arrangement when in use, medical care
Personnel, can be by the liquid in external water capsule through water pocket in water injection pipe injection through external extruding external water capsule, and interior water pocket expansion presss from both sides it
If catheter diameter reduce, so as to adjust the drainage flow of cerebrospinal fluid in conduit, with good clinical safety, meet cerebrospinal fluid
Circulating pressure need.
2nd, volume controlled type Ventriculo peritoneal shunt pipe (203724609U), the present invention is neurosurgery hydrocephalic operation
A kind of medical apparatus for implanting used during treatment.When hydrocephalic falls ill, it is necessary to the excessive cerebrospinal fluid of encephalic
It is diverted to abdominal cavity to go, the adverse reaction alleviated intracranial hypertension and cause, makes encephalic maintain to be suitable for the pressure of patient, so as to reach
Therapeutic effect.Volume controlled type Ventriculo peritoneal shunt pipe, it has a reservoir made using elastomeric material, the reservoir
Two ends are equipped with two check valves of direction identical, and reservoir volume is in 2-6ml.In hydrocephalic's Post operation, can be according to need
Appropriate compression number is carried out daily, and the appropriate cerebrospinal fluid of drainage controls clinical symptoms, reaches clinical cure to abdominal cavity.
3rd, a kind of ventricles of the brain-abdominal cavity shunt device of cerebrospinal fluid (104107460A), a kind of ventricles of the brain-abdominal cavity cerebrospinal fluid shunt dress
Put, the part flow arrangement includes that one is used to draw in ICV cerebrospinal fluid for inserting the subcutaneous external water capsule of abdominal cavity of patients and one
The conduit in abdominal cavity is flow to, an interior water pocket for extruded conduit is arranged with the outer wall of the conduit, interior water pocket passes through water filling
Pipe is connected with external water capsule, and water injection pipe is provided with the check valve of water pocket in for liquid in external water capsule to be introduced, the interior water pocket
A liquid pumping hole for discharging liquid in its inner chamber is provided with, the liquid pumping hole is by a silica gel sealing for being used to be pierced into liquid pumping needle
Pad sealing.When in use, medical personnel, can be by the liquid in external water capsule through water filling through external extruding external water capsule for the part flow arrangement
Water pocket in pipe injection, interior water pocket expansion reduces the catheter diameter of its sandwiched, so as to adjust the drainage flow of cerebrospinal fluid in conduit, has
There is good clinical safety, meet the circulating pressure needs of cerebrospinal fluid.
4th, Ventriculo peritoneal shunt installed capacity control method and volume controlled type Ventriculo peritoneal shunt pipe (103800992A),
A kind of present invention medical apparatus for implanting used when being neurosurgery hydrocephalic's operative treatment.In hydrocephalic
During morbidity, the excessive cerebrospinal fluid shunt of encephalic need to be gone to abdominal cavity, alleviate the adverse reaction that intracranial hypertension causes, maintain encephalic
It is suitable for the pressure of patient, so as to reach therapeutic effect.Ventriculo peritoneal shunt installed capacity control method, it uses elastomeric material
The reservoir of no pressure is made, reservoir two ends set two one-way cocks, csf flow is made to abdomen by artificial pressing reservoir
Cerebrospinal fluid capacity in chamber end control reservoir.Realize the volume controlled type brain of the Ventriculo peritoneal shunt installed capacity control method
Room peritoneal shunt pipe, it has a reservoir made using elastomeric material, and the reservoir two ends are equipped with direction identical two
Individual check valve, and reservoir volume is in 2-6ml.In hydrocephalic's Post operation, appropriate pressing can be daily carried out as needed
Number of times, the appropriate cerebrospinal fluid of drainage reaches clinical cure to abdominal cavity.
But above-mentioned existing invention/utility model patent 203970988U, 203724609U, 104107460A,
The isocon of 103800992A designs can only adjust pressure, it is impossible to prevent the transfer of cancer cell, therefore in the urgent need to there is a kind of energy
The isocon for enough preventing cancer cell from spreading, to reduce the generation of above-mentioned phenomenon.
The content of the invention
It is an object of the invention to overcome the deficiencies in the prior art, there is provided one kind physical method simply efficiently prevents cancer thin
The Ventriculo peritoneal shunt pipe of born of the same parents' diffusion, can effectively prevent intracerebral cancer cell to intraperitoneal diffusion.
The purpose of the present invention is achieved through the following technical solutions：
The invention provides a kind of simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading, the isocon includes
Body, side opening and cell sieve, the body closed at both ends are provided with symmetrical side opening on the side wall at body both ends, pipe
It is provided with cell sieve in vivo；The cell sieve is located between the side opening of both ends.In two ends one end implantation ventricles of the brain of the body, separately
One end implantation is intraperitoneal.
Preferably, the cell sieve is prepared using nanofiber, and aperture is 50-100nm.According to the straight of ICT cell
Footpath, selection is less than the aperture of ICT cell, so as to prevent cancer cell from passing through.
Preferably, the tube length is 100-140cm.
Preferably, the aperture of the side opening is 0.1mm, and side opening is distributed in body both ends and is put in 15cm apart from end points.
Preferably, the body is emulsion tube.
Preferably, it is provided with graduation mark on the body lateral wall., it is necessary to leading brain when in isocon one end implantation ventricles of the brain
Room punctures, and the graduation mark is used for localised puncture depth.Paracentesis depth is no more than 15cm.
Preferably, the cross section of the body is circle, and internal diameter is 1-1.5mm.The cell sieve diameter and internal diameter of tube body
It is identical.
Principle of the invention is：
In ICV cerebrospinal fluid cancer cell by side opening enter isocon tubular body after, due to cancer cell with diameter greater than
Cell mesh size, can be by cell sieve filtration at ventricles of the brain end, it is impossible to enter abdominal end, so as to prevent cancer cell from spreading.
When isocon of the present invention is used, in one end implantation ventricles of the brain, other end implantation is intraperitoneal；Ventricles of the brain end implantation depth
About 5-10cm, it is ensured that body is just in the ventricles of the brain (brain major part is brain parenchym, ventricles of the brain very little)；The requirement of abdominal end paracentesis depth
Smaller, side opening can be intraperitoneal.
Compared with prior art, the present invention has following beneficial effect：Isocon simple structure of the present invention, if
Meter is reasonable；Cell sieve is the mesh-like structure of aperture 50-100nm, can effectively filter cancer cell, can effectively prevent brain
The postoperative encephalic cancer cell of room-peritoneal shunt spreads to abdominal cavity.
Brief description of the drawings
The detailed description made to non-limiting example with reference to the following drawings by reading, further feature of the invention,
Objects and advantages will become more apparent upon：
Fig. 1 prevents cancer cell from spreading Ventriculo peritoneal shunt pipe schematic diagram for the present invention；
Fig. 2 is A-A profiles in Fig. 1；
Fig. 3 is B-B profiles in Fig. 1；
Wherein：1- bodys；2- cell sieves；3- side openings；4- graduation marks.
Specific embodiment
With reference to specific embodiment, the present invention is described in detail.Following examples will be helpful to the technology of this area
Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that to the ordinary skill of this area
For personnel, without departing from the inventive concept of the premise, some changes and improvements can also be made.These belong to the present invention
Protection domain.
Embodiment 1
A kind of simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading is present embodiments provided, such as Fig. 1-Fig. 3 institutes
Show, the isocon includes body 1, side opening 3 and cell sieve 2, the closed at both ends of the body 1 sets on the side wall at the both ends of body 1
It is equipped with symmetrical side opening 3, body 1 and is provided with cell sieve 2；The cell sieve 2 is located between both ends side opening 3.It is described
In two ends one end implantation ventricles of the brain of body 1, other end implantation is intraperitoneal.
The cell sieve 2 is prepared using nanofiber, and aperture is 50-100nm.According to the diameter of ICT cell, choosing
The aperture less than ICT cell is selected, so as to prevent cancer cell from passing through.
The length of the body 1 is 100-140cm.
The aperture of the side opening 3 is 0.1mm, and side opening 3 is distributed in the both ends of body 1 and is put in 15cm apart from end points.
The body 1 is emulsion tube.
Graduation mark 4 is provided with the lateral wall of the body 1., it is necessary to the leading ventricles of the brain are worn when in isocon one end implantation ventricles of the brain
Thorn, the graduation mark 4 is used for localised puncture depth.
The cross section of the body 1 is circle, and internal diameter is 1-1.5mm.The diameter of the cell sieve 2 is identical with the internal diameter of body 1.
Principle of the invention is：
Cancer cell is after side opening 3 enters the inside of isocon body 1 in ICV cerebrospinal fluid, because cancer cell diameter is big
In the aperture of cell sieve 2, can be filtered at ventricles of the brain end by cell sieve 2, it is impossible to enter abdominal end, so as to prevent cancer cell from spreading.
When isocon of the present invention is used, in one end implantation ventricles of the brain, other end implantation is intraperitoneal；Ventricles of the brain end implantation depth
About 5-10cm, it is ensured that body 1 is just in the ventricles of the brain (brain major part is brain parenchym, ventricles of the brain very little)；Abdominal end paracentesis depth will
Ask smaller, side opening 3 can be intraperitoneal.
The present invention has following beneficial effect：Isocon simple structure of the present invention, it is reasonable in design；Cell sieve 2
It is the mesh-like structure of aperture 50-100nm, can effectively filters cancer cell, after effectively can prevents ventriculo-peritoneal shunt
Encephalic cancer cell spreads to abdominal cavity.
Specific embodiment of the invention is described above.It is to be appreciated that the invention is not limited in above-mentioned
Particular implementation, those skilled in the art can within the scope of the claims make a variety of changes or change, this not shadow
Sound substance of the invention.In the case where not conflicting, feature in embodiments herein and embodiment can any phase
Mutually combination.
Claims (7)
1. a kind of simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading, it is characterised in that the isocon includes pipe
Body, side opening and cell sieve, the body closed at both ends are provided with symmetrical side opening, body on the side wall at body both ends
Inside it is provided with cell sieve；The cell sieve is located between the side opening of both ends.
2. the simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading according to claim 1, it is characterised in that institute
State cell sieve to be prepared using nanofiber, aperture is 50-100nm.
3. the simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading according to claim 1, it is characterised in that institute
Tube length is stated for 100-140cm.
4. the simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading according to claim 1, it is characterised in that institute
The aperture of side opening is stated for 0.1mm, side opening is distributed in body both ends within end points 15cm.
5. the simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading according to claim 1, it is characterised in that institute
Body is stated for emulsion tube.
6. the simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading according to claim 1, it is characterised in that institute
State and be provided with graduation mark on body lateral wall.
7. the simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading according to claim 1, it is characterised in that institute
It is circle to state the cross section of body, and internal diameter is 1-1.5mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710082050.2A CN106823100A (en) | 2017-02-15 | 2017-02-15 | The simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710082050.2A CN106823100A (en) | 2017-02-15 | 2017-02-15 | The simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106823100A true CN106823100A (en) | 2017-06-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710082050.2A Pending CN106823100A (en) | 2017-02-15 | 2017-02-15 | The simple Ventriculo peritoneal shunt pipe for efficiently preventing cancer cell from spreading |
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| CN (1) | CN106823100A (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201333213Y (en) * | 2009-01-06 | 2009-10-28 | 王拥军 | Filter for ncurolymph purifying device and pipeline system |
| CN101653637A (en) * | 2009-08-03 | 2010-02-24 | 方乃成 | Bullet-shaped cerebral porous drainage tube and cerebral drainage device adopting same |
| US20100222732A1 (en) * | 2007-09-10 | 2010-09-02 | Sevrain Lionel C | Anti-clogging ventricular catheter for cerebrospinal fluid drainage |
| CN102961789A (en) * | 2012-11-27 | 2013-03-13 | 宋修会 | Special cerebral hemorrhage drainage system |
| CN103212118A (en) * | 2013-01-18 | 2013-07-24 | 中国人民解放军第四军医大学 | Retroinfection-prevention enteric cavity shunting device for treating hydrocephalus |
| US20130226066A1 (en) * | 2012-02-23 | 2013-08-29 | Jung-Tung Liu | Apparatus for monitoring cerebrospinal fluid drainage |
| CN103933627A (en) * | 2014-04-08 | 2014-07-23 | 王雪霏 | CTC blood filtering and dialyzing system |
| CN104758988A (en) * | 2015-04-09 | 2015-07-08 | 北京市神经外科研究所 | Inferior regulation ventriculo-peritoneal shunt pipe |
| CN105013064A (en) * | 2015-08-26 | 2015-11-04 | 中国人民解放军第二军医大学 | Improved external ventricular drainage tube |
-
2017
- 2017-02-15 CN CN201710082050.2A patent/CN106823100A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100222732A1 (en) * | 2007-09-10 | 2010-09-02 | Sevrain Lionel C | Anti-clogging ventricular catheter for cerebrospinal fluid drainage |
| CN201333213Y (en) * | 2009-01-06 | 2009-10-28 | 王拥军 | Filter for ncurolymph purifying device and pipeline system |
| CN101653637A (en) * | 2009-08-03 | 2010-02-24 | 方乃成 | Bullet-shaped cerebral porous drainage tube and cerebral drainage device adopting same |
| US20130226066A1 (en) * | 2012-02-23 | 2013-08-29 | Jung-Tung Liu | Apparatus for monitoring cerebrospinal fluid drainage |
| CN102961789A (en) * | 2012-11-27 | 2013-03-13 | 宋修会 | Special cerebral hemorrhage drainage system |
| CN103212118A (en) * | 2013-01-18 | 2013-07-24 | 中国人民解放军第四军医大学 | Retroinfection-prevention enteric cavity shunting device for treating hydrocephalus |
| CN103933627A (en) * | 2014-04-08 | 2014-07-23 | 王雪霏 | CTC blood filtering and dialyzing system |
| CN104758988A (en) * | 2015-04-09 | 2015-07-08 | 北京市神经外科研究所 | Inferior regulation ventriculo-peritoneal shunt pipe |
| CN105013064A (en) * | 2015-08-26 | 2015-11-04 | 中国人民解放军第二军医大学 | Improved external ventricular drainage tube |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170613 |
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| RJ01 | Rejection of invention patent application after publication |