CN106822328A - The preparing raw material and preparation technology of the bright eyes patch of health treatment - Google Patents
The preparing raw material and preparation technology of the bright eyes patch of health treatment Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The present invention relates to the raw material and preparation technology of a kind of bright eyes patch of health treatment.It is the research carried out on the basis of the bright eyes patch raw material of existing Lin doctor's board and preparation technology, raw material and preparation technology of the present invention including bright eyes patch.Technique is:Chrysanthemum indicum, the red sage root, climbing groundsel, golden cypress, the coptis, pearl powder, cassia seed, moutan bark, arillus longan, mulberry fruit, borneol and Sodium Benzoate are taken, through techniques such as decoction, filtration, concentrations, bright eyes is made by purified water dilution and is pasted.Health treatment of the present invention has clearing heat and detoxicating, promoting blood circulation and removing obstruction in channels, the health-care efficacy for clearing liver and improving vision.
Description
Technical field
It is specifically a kind of bright the present invention relates to the raw material and preparation technology of a kind of health treatment
The raw material and preparation technology of eyes patch.
Background technology
The raw material and preparation technology of existing bright eyes patch, although bright eyes are posted and is compared into
Ripe production technology, but its production technology stability and reappearance and product quality
The leeway that curative effect is improved.
The content of the invention
It is an object of the invention to provide it is a kind of more effectively with the bright eyes of the production of process stabilizing
The raw material and preparation technology of patch.
The detailed process of raw material and preparation technology of the present invention including bright eyes patch.Its technology
Scheme is:
A kind of preparing raw material of the bright eyes patch of health treatment, the mass parts of its raw material are:
Chrysanthemum indicum 200-600 parts, red sage root 300-700 parts, climbing groundsel 200-600 parts,
Golden cypress 100-400 parts, coptis 50-400 parts, cassia seed 10-200 parts,
Moutan bark 50-500 parts, arillus longan 10-100 parts, mulberry fruit 30-200 parts,
Borneol 10-50 parts, pearl powder 50-500 parts, Sodium Benzoate 3-10 parts.
The preparation technology of described health treatment bright eyes patch is:
Step 1, from raw material and weigh mass parts.
Step 2, the ethanol that described borneol is added mass concentration 95%, are made mass concentration
The solution of 5%-10%, filtration;Described Sodium Benzoate is added water, mass concentration is made
The solution of 10%-20%, filtration;Two kinds of filtrates are merged again, stirring is collected standby.
Step 3, described pearl powder is added 4 times of water of quality, decocted, every 2 hours
Stirring once, and is incubated 48 hours, lets cool to 20-30 DEG C, filters, and collects filtrate standby
With.
Step 4, by described chrysanthemum indicum, the red sage root, cassia seed, the coptis, moutan bark, Huang
Cypress, climbing groundsel, arillus longan and mulberry fruit add 8 times of water of quality, decoct 2 hours, decocting liquid
After pouring out, then the decocting of 6 times of quality is added to boil 1 hour, decocting liquid is poured out;Then will be front and rear
Decocting liquid twice merges, filtration;Mass density 1.10 is concentrated filtrate to, is let cool
To 20-30 DEG C;Again plus the ethanol of mass concentration 95%, the mass content of ethanol is made up to 60%,
48 hours are stood, filtration;Ethanol is reclaimed from filtrate, until do not conform to ethanol in filtrate,
Then the mass concentration for being concentrated under reduced pressure into raw material in concentrate is 5-6%.
Step 5, by the constantly equidirectional stirring of the filtrate of step 4, and be slowly added into step 2
With the filtrate in step 3, continue to stir and evenly mix;Purified water is added to be diluted to after all pouring into
Mass concentration is 1.8%, filtration, obtains filtrate.
Step 6, the filtrate that step 5 is made quantitatively is injected with quantitative filling and sealing machine it is built-in with
In the aluminium foil bag of non-woven bag, sealing, packaging, sterilization, storage.
The present invention is entered on the basis of the raw material and preparation technology of existing bright eyes patch
Capable research, is made that a kind of original that is new, being improve than existing raw material and preparation technology
Material and preparation technology.
Raw material of the present invention and preparation technology enhance the steady of bright eyes patch raw material and preparation technology
Qualitative and reappearance, is more beneficial for production and product quality and the health-care effect of bright eyes patch.
The raw material of bright eyes patch is scientific and reasonable, and selection is safer, it then follows Chinese Traditional Medicine
Health care is theoretical, meets health treatment composition principle and laws and regulations requirement.Motherland's medical science is recognized
For the eye disease such as visual fatigue, myopia is generally deficiency of liver-blood, caused by the deficiency of liver-yin and kidney-yin.When
With promoting blood circulation and removing obstruction in channels, it is the rules for the treatment of to clear liver and improve vision.Therefore it is clearing heat and detoxicating from chrysanthemum indicum in side, clearly
Liver improving eyesight is the monarch drug in a prescription in side.It is aided with climbing groundsel, cassia seed clearing heat and detoxicating, clears liver and improve vision;
Pearl powder clearing heat for calming endogenous wind, tranquilizing mind, shade removing;The red sage root, moutan bark clearing heat and cooling blood,
Promoting blood circulation and removing obstruction in channels, monarch drug in a prescription is clearing heat and detoxicating to increase for stasis-dispelling and pain-killing, and the power clear liver and improved vision is altogether minister
Medicine.Golden cypress heat-clearing and damp-drying drug, purging intense heat and detonicating;Arillus longan tonifying heart and spleen, nourishing blood and tranquilization;Mulberry
Shen liver-kidney tonifyings, nourishes blood and promotes the production of body fluid, to increase eye nutrition, improvement eyesight is adjutant.Ice
Piece is strongly fragrant except heat-clearing dissipates, and outside anti-inflammatory analgetic, and fragrance is walked to alter, all in the current Zhu Jinger sides of drawing
Make medicine carried out by the through disease of medicine.More than all medicines tie in, gather altogether clearing heat and detoxicating, promoting blood circulation is logical
Network, the health-care efficacy for clearing liver and improving vision.
The stable preparation process of bright eyes patch, favorable reproducibility is easy to operate, produces
Reliable product quality.
Specific embodiment
The raw material and preparation technology of the bright eyes patch of the present invention include herein below.
First, the mass parts that the present invention prepares bright eyes patch raw material are:
2nd, the preparation technology of bright eyes patch of the invention is:
1st, from raw material and mass parts are weighed.
The 2nd, described borneol is added the ethanol of mass concentration 95%, mass concentration 5%-10% is made
Solution, filtration;Described Sodium Benzoate is added water, mass concentration 10%-20% is made
Solution, filtration;Two kinds of filtrates are merged again, stirring is collected standby.
3rd, described pearl powder is added into 4 times of water of quality, is decocted, stirred every 2 hours
Once, and be incubated 48 hours, let cool to 20-30 DEG C, filter, collect filtrate it is standby.
4th, by described chrysanthemum indicum, the red sage root, cassia seed, the coptis, moutan bark, golden cypress,
Climbing groundsel, arillus longan and mulberry fruit add 8 times of water of quality, decoct 2 hours, and decocting liquid is poured out
Afterwards, then add 6 times of quality decocting boil 1 hour, decocting liquid is poured out;Then by before and after twice
Decocting liquid merge, filtration;Mass density 1.10 is concentrated filtrate to, is let cool to 20-30
℃;Again plus the ethanol of mass concentration 95%, make the mass content of ethanol up to 60%, stand 48
Hour, filtration;Ethanol is reclaimed from filtrate, until being free of ethanol in filtrate, is then subtracted
The mass concentration that pressure is concentrated into raw material in concentrate is 5-6%.
5th, by the constantly equidirectional stirring of the filtrate of step 4, and step 2 and step are slowly added into
Filtrate in rapid 3, continues to stir and evenly mix;Purified water is added to be diluted to quality after all pouring into
Concentration is 1.8%, filtration, obtains filtrate.
6th, the filtrate that step 5 is made quantitatively is injected with quantitative filling and sealing machine and is built-in with non-woven bag
Aluminium foil bag in, sealing, packaging, sterilization, storage.
The bright eyes patch health-care effect test report of health treatment of the present invention
1 data and method
1.1 physical data:30 users are selected from my company personnel and employee family members, for a long time
Make computer user 15, the old dry and astringent tired person 10 of eye, myopia of student amblyope 5,
Diagnosis is clear and definite, symptom typical case, is ophthalmic uncomfortable patient caused by liver-fire flaming.12 years old age-
60 years old, male or female.Other external application eye stickers are not used in experiment.
1.2 methods:First clean eye, packaging bag is torn along breach, take out patch, open nonwoven
Cloth pad pasting, then eye sticker is directly spread on circumference of eyes, close mesh about 15-20 minutes after throw off
.Daily 2 times, the course for the treatment of 2 weeks.
1.3 points for attention
Closed one's eyes when using, liquid can't enter in eyes;External use plaster please don't eat;Skin
Allergy sufferers are used with caution;Disabled at skin injury.Children and teenager must use under monitoring of being grown up.
2 interpretations of result
2.1 effect standards
It is effective:There is good mitigation to eye swelling fatigue, amblyopia symptom is clearly better.
Effectively:There is certain mitigation to ophthalmic uncomfortable, amblyopia symptom has certain alleviation.It is invalid:
To ophthalmic uncomfortable without mitigation, amblyopia symptom is without alleviation.
2.2 use result
Result on trial shown, the ophthalmic uncomfortable and eye strain caused to liver-fire flaming are pasted using bright eyes
And the alleviation to amblyopia, definite effect, total effective rate reached 93.0%.(being specifically shown in Table one).
During the bright eyes of application are pasted, there is allergic reaction except even, stop using rear symptom to disappear, not
It was found that other adverse reactions.
Table one applies eye paste observation of curative effect result
3 discuss
Bright eyes patch is by the strong osmotic to eye part skin, targeting and eyeground focus portion
Position, absorbs conditioning eye qi and blood balance, improves ocular circulation, comprehensively rapid supplement eye
Nutrition, improves ocular immune power and anti-oxidantization ability, promotes part tissue of eye metabolism, clearly
Thermal detoxification, it is promoting blood circulation and removing obstruction in channels, clear liver and improve vision.In addition this product can improve ocular circulation regulation and regard
Nerve, so as to reach alleviation ophthalmic uncomfortable, thus with kopiopia is alleviated, treats the work of amblyopia
With.
Claims (6)
1. the preparing raw material of a kind of health treatment bright eyes patch, its raw material is:
Chrysanthemum indicum, the red sage root, climbing groundsel, golden cypress, the coptis, cassia seed, moutan bark, arillus longan, mulberry fruit, borneol, pearl powder and Sodium Benzoate.
2. the preparing raw material of health treatment according to claim 1 bright eyes patch, the mass parts of its raw material are:
Chrysanthemum indicum 200-600 parts, red sage root 300-700 parts, climbing groundsel 200-600 parts,
Golden cypress 100-400 parts, coptis 50-400 parts, cassia seed 10-200 parts,
Moutan bark 50-500 parts, arillus longan 10-100 parts, mulberry fruit 30-200 parts,
Borneol 10-50 parts, pearl powder 50-500 parts, Sodium Benzoate 3-10 parts.
3. a kind of preparation technology of the bright eyes patch of health treatment is:
Step 1, from raw material and weigh mass parts;
Step 2, described borneol is added into ethanol, be made solution, filtered;Described Sodium Benzoate is added water, solution is made, filtered;Two kinds of filtrates are merged again, stirring is collected standby;
Step 3, described pearl powder is added water, decocted, insulation lets cool, and filters, and collects filtrate standby;
Step 4, described chrysanthemum indicum, the red sage root, cassia seed, the coptis, moutan bark, golden cypress, climbing groundsel, arillus longan and mulberry fruit are added water, decocted, after decocting liquid is poured out, add water decoction, decocting liquid is poured out;Then front and rear decocting liquid twice is merged, filtration;Filtrate decompression is concentrated, is let cool;Again plus ethanol, stand, filtration;Ethanol is reclaimed from filtrate, until being free of ethanol in filtrate, is then concentrated under reduced pressure;
Step 5, by the constantly equidirectional stirring of the filtrate of step 4, and be slowly added into the filtrate in step 2 and step 3, continue to stir and evenly mix;The mass concentration for adding purified water to be diluted to raw material in solution after all pouring into is 1.8%, and filtration obtains filtrate;
Step 6, the filtrate that step 5 is made quantitatively is injected with quantitative filling and sealing machine it is built-in with the aluminium foil bag of non-woven bag, seals, packaging, sterilization, storage.
Filtrate is quantitative 1.5-2 grams in described aluminium foil bag, also can be quantitative by different specifications.
4. preparation technology according to claim 3, step 2 is specially:Described borneol is added the ethanol of mass concentration 95%, the solution of mass concentration 5%-10% is made, filtered;Described Sodium Benzoate is added water, the solution of mass concentration 10%-20% is made, filtered;Two kinds of filtrates are merged again, stirring is collected standby.
5. preparation technology according to claim 3, step 3 is specially:Described pearl powder is added into 4 times of water of quality, is decocted, every stirring in 2 hours once, and be incubated 48 hours, let cool to 20-30 DEG C, filtered, collect filtrate standby.
6. preparation technology according to claim 3, step 4 is specially:Described chrysanthemum indicum, the red sage root, cassia seed, the coptis, moutan bark, golden cypress, climbing groundsel, arillus longan and mulberry fruit are added into 8 times of water of quality, is decocted 2 hours, after decocting liquid is poured out, then add the decocting of 6 times of quality to boil 1 hour, decocting liquid is poured out;Then front and rear decocting liquid twice is merged, filtration;Mass density 1.10 is concentrated filtrate to, is let cool to 20-30 DEG C;Again plus the ethanol of mass concentration 95%, make the mass content of ethanol up to 60%, stand 48 hours, filtration;Ethanol is reclaimed from filtrate, until being free of ethanol in filtrate, the mass concentration for being then concentrated under reduced pressure into raw material in concentrate is 5-6%.
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CN105395371A (en) * | 2015-12-18 | 2016-03-16 | 安徽省微赢生物科技有限公司 | Eye brightening patch and preparation method thereof |
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CN105395371A (en) * | 2015-12-18 | 2016-03-16 | 安徽省微赢生物科技有限公司 | Eye brightening patch and preparation method thereof |
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