CN106818791A - A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and preparation method thereof - Google Patents

A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and preparation method thereof Download PDF

Info

Publication number
CN106818791A
CN106818791A CN201611202580.8A CN201611202580A CN106818791A CN 106818791 A CN106818791 A CN 106818791A CN 201611202580 A CN201611202580 A CN 201611202580A CN 106818791 A CN106818791 A CN 106818791A
Authority
CN
China
Prior art keywords
parts
emamectin
benzoate
solution
eugenol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201611202580.8A
Other languages
Chinese (zh)
Inventor
牧成林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Huafei
Original Assignee
Sun Huafei
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Huafei filed Critical Sun Huafei
Priority to CN201611202580.8A priority Critical patent/CN106818791A/en
Publication of CN106818791A publication Critical patent/CN106818791A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
    • A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system

Abstract

The emamectin-benzoate mite killing suspending agent of a kind of eugenol synergy, it is characterised in that it is prepared from by following raw material：Emamectin benzoate, methyl alcohol, phosphoric acid solution, toluene, isopropyl acetate, t-butyl methyl ether, benzoic acid, n-hexane, clove leaf oil, sodium hydroxide solution, hexamethylene, sodium citrate, dimethyl carbonate, potassium carbonate, petroleum ether, acetone, shitosan, acetic acid, AEO, atoleine, vinylacetate, ammonium persulfate solution, HMPA, dimethylformamide, sodium lignin sulfonate, ethylene glycol, appropriate deionized water.Mite killing suspending agent of the invention can efficiently lure acarid, acarid is effectively killed, with excellent synergistic effect, acaricidal field dosage is reduced, residues of pesticides and the harm to beneficial organism can be effectively reduced, while reducing cost accounting and mitigating the pollution to environment.

Description

A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and its Preparation method
Technical field
The invention belongs to agricultural pesticide field, and in particular to a kind of emamectin-benzoate of eugenol synergy Mite killing suspending agent and preparation method thereof.
Background technology
It is current main to use chemical pesticide control agricultural pest, but over time, the drawbacks of chemical pesticide by Gradually it is exposed, of particular concern is the rampant and resistance problem mad again of residues of pesticides, insect, these problems promotes people to open Beginning finds the substitute of chemical pesticide.AVM is that antibioticses desinsection kills full mite agent, belongs to biological source insecticide, with chemistry Unlike agricultural chemical insecticide, AVM mainly by disturbing insect nervous physiology activity, stimulates release GABA, And aminobutyric acid has inhibitory action to the nerve conduction of arthropod, mite class adult, nymph and insect larvae and AVM connect There is paralysis symptom after touch, inertia, do not take food, it is dead after 2~4 days.AVM is to insect predator and insect parasite Though there is direct action of contace poison, because plant surface residual is few, therefore to the damage very little of beneficial insect.AVM is in soil by soil Absorption will not be moved, and can be decomposed by the microorganisms, thus in the environment without cumulative function.Due to not causing insect to take off rapidly Water, AVM lethal effect is more slow.
Author Chen Fuliang exists《The development of the avermectin micro-emulsion containing organosilicon auxiliary agent》In one text, with 7% Avermectin Element, 6% cyclohexanone, 4% dimethyl sulfoxide (DMSO), 5% organosilicon auxiliary agent Silwet408 and balance of water, are obtained AVM micro- Emulsion；Addition organosilicon auxiliary agent can not only significantly reduce liquid surface tension and improve liquid blade surface wetting, Ability is opened up, increases the expanding area of liquid, and liquid can be made to enter hidden close insect hiding place, and promote plant leaf surface pair The absorption of active ingredient and enter epidermis, extend its lasting period；But active ingredient is single Avermectin in the microemulsion Element, its Insecticiding-miticiding is inefficient, and lethal effect is slow.
The content of the invention
It is an object of the invention to provide the emamectin benzoate benzoic acid of a kind of efficient and lasting eugenol synergy Salt mite killing suspending agent and preparation method thereof.
To achieve these goals, the present invention is adopted the following technical scheme that：
The emamectin-benzoate mite killing suspending agent of a kind of eugenol synergy, it is characterised in that it is by following weight The raw material of part is prepared from：Emamectin benzoate 6-8 parts, methyl alcohol 120-150 parts, phosphoric acid solution 30-40 parts, toluene 200- 250 parts, isopropyl acetate 60-70 parts, t-butyl methyl ether 2-3 parts, benzoic acid 12-15 parts, n-hexane 180-200 parts, cloves Leaf oil 5-6 parts, sodium hydroxide solution 30-40 parts, hexamethylene 70-80 parts, sodium citrate 3-4 parts, dimethyl carbonate 6-8 parts, carbon Sour potassium 1-1.5 parts, petroleum ether 30-35 parts, acetone 80-100 parts, shitosan 18-20 parts, acetic acid 4-5 parts, aliphatic alcohol polyethenoxy Ether 2-3 parts, atoleine 80-100 parts, vinylacetate 5-6 parts, ammonium persulfate solution 5-6 parts, HMPA 0.5- 1 part, dimethylformamide 1-2 parts, sodium lignin sulfonate 2-3 parts, ethylene glycol 3-4 parts, appropriate deionized water.
The emamectin-benzoate mite killing suspending agent of described eugenol synergy, it is characterised in that it is by such as Lower step is prepared from：
（1）At room temperature, emamectin benzoate is added in 2/3 methyl alcohol, is stirred to being completely dissolved, be slowly added dropwise phosphoric acid molten The mixed solution that liquid is configured with remaining methyl alcohol, continues to mix 1-2h after completion of dropping；1/2 toluene is added, continues mixed Conjunction stirring 1-2h, is transferred them in ice-water bath, continues to mix 5-6h, and centrifugation, precipitation is used and pre-cooled to 0 DEG C Remaining toluene wash 2-3 time, be vacuum dried；Product after vacuum drying is added to equivalent to emamectin benzoate weight Measure in the deionized water of 3-4 times of part, stirring dissolves it, add isopropyl acetate, regulation system PH is 8-9, mixes 30- 3-4h is stood after 40min, organic phase is separated；T-butyl methyl ether is added in organic phase, stirring makes it fully dissolve, room temperature Lower addition benzoic acid, mixes reaction 5-6h, is slowly added dropwise 1/2 n-hexane, continues to mix reaction after completion of dropping 4-5h, filtering, filter cake is washed 2-3 times with remaining n-hexane, is vacuum dried, and obtains emamectin-benzoate；
（2）Clove leaf oil is placed in vacuum distillation apparatus, 140-150 DEG C carries out vacuum distillation, collects cut；Cut is added to In sodium hydroxide solution, 5-6h is mixed, stood, separation water phase；After water mutually extracts 1-2 times using hexamethylene, in being neutralized to Property, stand a point liquid, leaving layer liquid；Sodium citrate is added, 20-30min is mixed, a point liquid, leaving layer liquid is stood；Transfer The vacuum distillation into vacuum distillation apparatus, collects 145-150 DEG C of cut；Cut, 1/3 dimethyl carbonate and potassium carbonate are thrown Enter in autoclave, be heated to 150-160 DEG C, normal pressure magnetic agitation 2-3h adds remaining dimethyl carbonate, rises high-temperature extremely 200-220 DEG C, Stress control is cooled to room temperature in 0.2-0.3MPa, heat-insulation pressure keeping magnetic agitation 6-8h, and filtering, filtrate neutralizes To neutral, using petroleum ether extraction, petroleum ether is reclaimed in vacuum distillation, obtains modified eugenol；
（3）By step（1）Product, step（2）Product be added in acetone, after mixing and stirring, be slowly added into shell In glycan, acetic acid and the solution configured equivalent to the deionized water of 30-35 times of acetic acid weight portion, after mixing and stirring, add To the solution that AEO and atoleine are configured, the turning with 2200-2500 turns/min in 50-55 DEG C of water-bath Fast constant temperature quickly stirs 25-30min, forms white " milky " liquid, leads to nitrogen 20-30min, adds vinylacetate, and mixing is equal After even, ammonium persulfate solution is slowly added dropwise, 65-70 DEG C is continued to stir 5-6h after completion of dropping, is washed with deionized 2-3 times, Centrifugation, 20-24h is dried in 60-65 DEG C of vacuum drying chamber, obtains loading the shitosan of emamectin-benzoate Sustained-release micro-spheres；
（4）By step（3）Product, HMPA, dimethylformamide be added to equivalent to step（3）Product weight Measure in the deionized water of 15-20 times of part, ultrasonic disperse 30-40min adds sodium lignin sulfonate, ethylene glycol, with 800-1000 Turn/the rotating speed of min stirring 25-30min, obtain the emamectin-benzoate mite killing suspending agent of eugenol synergy.
The emamectin-benzoate mite killing suspending agent of described eugenol synergy, it is characterised in that described The concentration of phosphoric acid solution is 0.5-0.6mol/L, and the concentration of described sodium hydroxide solution is 0.2-0.3mol/L, described mistake The concentration of ammonium sulfate is 0.1-0.2mol/L.
Beneficial effects of the present invention are：
The present invention is main acaricide with emamectin-benzoate, and compared to AVM parent, it is to Lepidoptera elder brother The activity of worm larva is generally improved, and is especially 6 times of AVM to the preventing and treating of acarid；Emamectin-benzoate Belong to biogenic pesticide, with its unique mechanism of action, be difficult to remain, can be biodegradable, it is safe and environment-friendly the advantages of, meet Develop the requirement of nuisanceless fruits and vegetables, pollution-free food；Present invention addition eugenol, and it is modified to it using dimethyl carbonate, with first Amino abamectin benzoate acts synergistically, and can not only kill insect, evil mite, worm's ovum, and can kill pathogen, increases Plus suspending agent miticidal effect of the present invention；The present invention wraps up AVM using shitosan, and using vinylacetate to shitosan Crosslinking, obtains sustained-release micro-spheres, can not only slow release medicine, extend the service life of medicament, it can be significantly reduced and store Middle resolution ratio is deposited, and shitosan can promote medicament to be absorbed by plants rapidly through Stoma of Leaves, further increase miticidal effect；This The mite killing suspending agent of invention can efficiently lure acarid, effectively kill acarid, with excellent synergistic effect, reduce acaricidal Field dosage, can effectively reduce residues of pesticides and the harm to beneficial organism, while reducing cost accounting and mitigating to ring The pollution in border.
Specific embodiment
The emamectin-benzoate mite killing suspending agent of the eugenol synergy of the present embodiment, it is by following weight portion Raw material be prepared from：8 parts of emamectin benzoate, 150 parts of methyl alcohol, 30 parts of phosphoric acid solution, 250 parts of toluene, isopropyl acetate 70 parts, 3 parts of t-butyl methyl ether, 15 parts of benzoic acid, 200 parts of n-hexane, 6 parts of clove leaf oil, 40 parts of sodium hydroxide solution, hexamethylene 80 parts of alkane, 4 parts of sodium citrate, 8 parts of dimethyl carbonate, 1.5 parts of potassium carbonate, 35 parts of petroleum ether, 100 parts of acetone, 20 parts of shitosan, 5 parts of acetic acid, 3 parts of AEO, 100 parts of atoleine, 6 parts of vinylacetate, 6 parts of ammonium persulfate solution, pregnancy 1 part of base phosphoric triamide, 2 parts of dimethylformamide, 3 parts of sodium lignin sulfonate, 4 parts of ethylene glycol, appropriate deionized water.
The emamectin-benzoate mite killing suspending agent of the eugenol synergy of the present embodiment, it is by following steps system It is standby to form：
（1）At room temperature, emamectin benzoate is added in 2/3 methyl alcohol, is stirred to being completely dissolved, be slowly added dropwise phosphoric acid molten The mixed solution that liquid is configured with remaining methyl alcohol, continues to mix 2h after completion of dropping；1/2 toluene is added, continues to mix Stirring 2h, is transferred them in ice-water bath, continues to mix 6h, and centrifugation, precipitation is used and pre-cooled to 0 DEG C of residue Toluene wash 3 times, vacuum drying；Product after vacuum drying is added to equivalent to 4 times of emamectin benzoate weight portion Deionized water in, stirring dissolve it, add isopropyl acetate, regulation system PH be 8-9, mix 40min after stand 4h, separates organic phase；T-butyl methyl ether is added in organic phase, stirring makes it fully dissolve, and benzoic acid is added at room temperature, Mix and react 6h, be slowly added dropwise 1/2 n-hexane, continue to mix reaction 5h after completion of dropping, filtering, filter cake is used surplus Remaining n-hexane is washed 3 times, vacuum drying, obtains emamectin-benzoate；
（2）Clove leaf oil is placed in vacuum distillation apparatus, 150 DEG C carry out vacuum distillation, collect cut；Cut is added to hydrogen-oxygen Change in sodium solution, mix 6h, stand, separation water phase；After water mutually extracts 2 times using hexamethylene, neutrality is neutralized to, stands and divide Liquid, leaving layer liquid；Sodium citrate is added, 30min is mixed, a point liquid, leaving layer liquid is stood；It is transferred to vacuum distillation dress Middle vacuum distillation is put, 150 DEG C of cut is collected；During cut, 1/3 dimethyl carbonate and potassium carbonate put into autoclave, plus To 160 DEG C, normal pressure magnetic agitation 3h adds remaining dimethyl carbonate to heat, rises high-temperature to 220 DEG C, and Stress control exists 0.3MPa, heat-insulation pressure keeping magnetic agitation 8h, is cooled to room temperature, and filtering, filtrate is neutralized to neutrality, using petroleum ether extraction, decompression Distillation recovery petroleum ether, obtains modified eugenol；
（3）By step（1）Product, step（2）Product be added in acetone, after mixing and stirring, be slowly added into shell In glycan, acetic acid and the solution configured equivalent to the deionized water of 35 times of acetic acid weight portion, after mixing and stirring, fat is added to Fat alcohol APEO and the solution of atoleine configuration, the rotating speed constant temperature with 2500 turns/min in 55 DEG C of water-baths are quickly stirred 30min is mixed, white " milky " liquid is formed, leads to nitrogen 30min, add vinylacetate, after being well mixed, be slowly added dropwise persulfuric acid Ammonium salt solution, 70 DEG C are continued to stir 6h after completion of dropping, are washed with deionized 3 times, centrifugation, are done in 65 DEG C of vacuum drying chambers Dry 24h, obtains loading the chitosan sustained-release microsphere of emamectin-benzoate；
（4）By step（3）Product, HMPA, dimethylformamide be added to equivalent to step（3）Product weight Measure in the deionized water of 20 times of part, ultrasonic disperse 40min adds sodium lignin sulfonate, ethylene glycol, with the rotating speed of 1000 turns/min Stirring 30min, obtains the emamectin-benzoate mite killing suspending agent of eugenol synergy.
Test method：Caught from field and come each 200 of cabbage caterpillar, heart-eating worm, vegetable aphid, planthopper, acarid, every kind of insect Individually it is placed in plastic tub, the dish leaf 2 of equivalent is put into each plastic tub, by the mite killing suspending agent dilute with water of the present embodiment 500 times, then the mite killing suspending agent after dilution is uniformly sprayed in plastic tub, dish leaf is stirred during sprinkling, make its comprehensively medicine, Plastic tub bottom retains without liquid, then covers plastic tub with gauze and seals, and then the insect of 24h and 48h is dead after statistics spray Die rate.
Result of the test：
The death rate after spray 24h The death rate after spray 48h
Cabbage caterpillar 83.6% 91.1%
Heart-eating worm 85.4% 93.2%
Vegetable aphid 81.6% 88.4%
Planthopper 83.5% 89.3%
Acarid 93.6% 98.6%

Claims (3)

1. the emamectin-benzoate mite killing suspending agent of a kind of eugenol synergy, it is characterised in that it by weighing as follows The raw material for measuring part is prepared from：Emamectin benzoate 6-8 parts, methyl alcohol 120-150 parts, phosphoric acid solution 30-40 parts, toluene 200- 250 parts, isopropyl acetate 60-70 parts, t-butyl methyl ether 2-3 parts, benzoic acid 12-15 parts, n-hexane 180-200 parts, cloves Leaf oil 5-6 parts, sodium hydroxide solution 30-40 parts, hexamethylene 70-80 parts, sodium citrate 3-4 parts, dimethyl carbonate 6-8 parts, carbon Sour potassium 1-1.5 parts, petroleum ether 30-35 parts, acetone 80-100 parts, shitosan 18-20 parts, acetic acid 4-5 parts, aliphatic alcohol polyethenoxy Ether 2-3 parts, atoleine 80-100 parts, vinylacetate 5-6 parts, ammonium persulfate solution 5-6 parts, HMPA 0.5- 1 part, dimethylformamide 1-2 parts, sodium lignin sulfonate 2-3 parts, ethylene glycol 3-4 parts, appropriate deionized water.
2. the emamectin-benzoate mite killing suspending agent of the eugenol synergy according to claims 1, it is special Levy and be, it is prepared from by following steps：
（1）At room temperature, emamectin benzoate is added in 2/3 methyl alcohol, is stirred to being completely dissolved, be slowly added dropwise phosphoric acid molten The mixed solution that liquid is configured with remaining methyl alcohol, continues to mix 1-2h after completion of dropping；1/2 toluene is added, continues mixed Conjunction stirring 1-2h, is transferred them in ice-water bath, continues to mix 5-6h, and centrifugation, precipitation is used and pre-cooled to 0 DEG C Remaining toluene wash 2-3 time, be vacuum dried；Product after vacuum drying is added to equivalent to emamectin benzoate weight Measure in the deionized water of 3-4 times of part, stirring dissolves it, add isopropyl acetate, regulation system PH is 8-9, mixes 30- 3-4h is stood after 40min, organic phase is separated；T-butyl methyl ether is added in organic phase, stirring makes it fully dissolve, room temperature Lower addition benzoic acid, mixes reaction 5-6h, is slowly added dropwise 1/2 n-hexane, continues to mix reaction after completion of dropping 4-5h, filtering, filter cake is washed 2-3 times with remaining n-hexane, is vacuum dried, and obtains emamectin-benzoate；
（2）Clove leaf oil is placed in vacuum distillation apparatus, 140-150 DEG C carries out vacuum distillation, collects cut；Cut is added to In sodium hydroxide solution, 5-6h is mixed, stood, separation water phase；After water mutually extracts 1-2 times using hexamethylene, in being neutralized to Property, stand a point liquid, leaving layer liquid；Sodium citrate is added, 20-30min is mixed, a point liquid, leaving layer liquid is stood；Transfer The vacuum distillation into vacuum distillation apparatus, collects 145-150 DEG C of cut；Cut, 1/3 dimethyl carbonate and potassium carbonate are thrown Enter in autoclave, be heated to 150-160 DEG C, normal pressure magnetic agitation 2-3h adds remaining dimethyl carbonate, rises high-temperature extremely 200-220 DEG C, Stress control is cooled to room temperature in 0.2-0.3MPa, heat-insulation pressure keeping magnetic agitation 6-8h, and filtering, filtrate neutralizes To neutral, using petroleum ether extraction, petroleum ether is reclaimed in vacuum distillation, obtains modified eugenol；
（3）By step（1）Product, step（2）Product be added in acetone, after mixing and stirring, be slowly added into shell In glycan, acetic acid and the solution configured equivalent to the deionized water of 30-35 times of acetic acid weight portion, after mixing and stirring, add To the solution that AEO and atoleine are configured, the turning with 2200-2500 turns/min in 50-55 DEG C of water-bath Fast constant temperature quickly stirs 25-30min, forms white " milky " liquid, leads to nitrogen 20-30min, adds vinylacetate, and mixing is equal After even, ammonium persulfate solution is slowly added dropwise, 65-70 DEG C is continued to stir 5-6h after completion of dropping, is washed with deionized 2-3 times, Centrifugation, 20-24h is dried in 60-65 DEG C of vacuum drying chamber, obtains loading the shitosan of emamectin-benzoate Sustained-release micro-spheres；
（4）By step（3）Product, HMPA, dimethylformamide be added to equivalent to step（3）Product weight Measure in the deionized water of 15-20 times of part, ultrasonic disperse 30-40min adds sodium lignin sulfonate, ethylene glycol, with 800-1000 Turn/the rotating speed of min stirring 25-30min, obtain the emamectin-benzoate mite killing suspending agent of eugenol synergy.
3. the emamectin-benzoate mite killing suspending agent of the eugenol synergy according to claims 1,2, its It is characterised by, the concentration of described phosphoric acid solution is 0.5-0.6mol/L, the concentration of described sodium hydroxide solution is 0.2- 0.3mol/L, the concentration of described ammonium persulfate solution is 0.1-0.2mol/L.
CN201611202580.8A 2016-12-23 2016-12-23 A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and preparation method thereof Withdrawn CN106818791A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611202580.8A CN106818791A (en) 2016-12-23 2016-12-23 A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611202580.8A CN106818791A (en) 2016-12-23 2016-12-23 A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and preparation method thereof

Publications (1)

Publication Number Publication Date
CN106818791A true CN106818791A (en) 2017-06-13

Family

ID=59135971

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611202580.8A Withdrawn CN106818791A (en) 2016-12-23 2016-12-23 A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and preparation method thereof

Country Status (1)

Country Link
CN (1) CN106818791A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111568886A (en) * 2020-06-16 2020-08-25 福建师范大学福清分校 Chinese and western medicine compound film coating agent for treating bovine acariasis and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101578040A (en) * 2006-11-07 2009-11-11 陶氏益农公司 Sprayable, controlled-release, male annihilation technique (MAT) formulation and insect control method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101578040A (en) * 2006-11-07 2009-11-11 陶氏益农公司 Sprayable, controlled-release, male annihilation technique (MAT) formulation and insect control method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111568886A (en) * 2020-06-16 2020-08-25 福建师范大学福清分校 Chinese and western medicine compound film coating agent for treating bovine acariasis and preparation method thereof
CN111568886B (en) * 2020-06-16 2022-09-13 福建师范大学福清分校 Chinese and western medicine compound film coating agent for treating bovine acariasis and preparation method thereof

Similar Documents

Publication Publication Date Title
CN102283216B (en) Acaricidal composition containing abamectin and etoxazole
CN104920441A (en) Pesticide composition for preventing and treating striped flea beetles
CN102210314B (en) Mollusk-killing composition containing niclosamide and carbaryl
CN102379300A (en) Acaricidal combination containing bifenazate and spirodiclofen
CN106332921B (en) A kind of plant insecticide and its preparation method and application
CN101278683A (en) Pollution-free plant source pesticide rotenone emulsifiable solution formulation and method of preparing the same
CN107333814A (en) Vegetable insecticide and preparation method thereof
CN108835115A (en) A kind of miticide composition containing fluazinam and Aphox
CN106818791A (en) A kind of emamectin-benzoate mite killing suspending agent of eugenol synergy and preparation method thereof
CN110024791A (en) Complex insecticidal composition and its application
CN106818726A (en) A kind of emamectin-benzoate mite killing suspending agent for suppressing mite egg hatching and preparation method thereof
CN106857698A (en) A kind of herbicide containing glyphosate and fluoroglycofen-ethyl
CN106818725A (en) A kind of emamectin-benzoate mite killing suspending agent of flufenzine synergy and preparation method thereof
CN106818727A (en) A kind of emamectin-benzoate mite killing suspending agent for suppressing chitin synthesis and preparation method thereof
CN106719749B (en) A kind of bactericidal composition of fluorine-containing azoles ring bacterium amine and its application
CN106818790A (en) Good emamectin-benzoate mite killing suspending agent of a kind of being compatible with the environment property and preparation method thereof
CN104365638A (en) Dihalopyrazole amide and lufenuron compound insecticidal composition
CN110024792A (en) Agricultural double-crossed Pesticidal combination and its application
CN106797943A (en) A kind of emamectin-benzoate mite killing suspending agent with entrapping function and preparation method thereof
CN102369941B (en) Insecticidal and acaricidal composition containing bifenazate and chlorfenapyr
CN106857646A (en) A kind of emamectin-benzoate mite killing suspending agent not developed immunity to drugs and preparation method thereof
CN106818796A (en) A kind of bactericidal composition of metsulfovax containing pyrrole with thifluzamide and its application
CN109197889A (en) A kind of seed treatment compositions of pyraclostrobin-containing, carboxin and clothianidin
CN108184857A (en) A kind of miticide composition containing second azoles mite nitrile with single carbonamidine
CN106879613A (en) It is a kind of to replace microemulsion containing matrine oil of organic solvent and preparation method thereof with soybean oil

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20170613

WW01 Invention patent application withdrawn after publication