CN106719749B - A kind of bactericidal composition of fluorine-containing azoles ring bacterium amine and its application - Google Patents

A kind of bactericidal composition of fluorine-containing azoles ring bacterium amine and its application Download PDF

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CN106719749B
CN106719749B CN201611072463.4A CN201611072463A CN106719749B CN 106719749 B CN106719749 B CN 106719749B CN 201611072463 A CN201611072463 A CN 201611072463A CN 106719749 B CN106719749 B CN 106719749B
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bacterium amine
azoles ring
ring bacterium
fluorine
bactericidal composition
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CN106719749A (en
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杨志鹏
王旭
李波
刘君良
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Shandong Binhai Hansheng Biological Technology Co., Ltd.
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QINGDAO TISUN BIOLOGIC SCIENCE CO Ltd
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The present invention relates to technical field of pesticide compounding, the application of bactericidal composition and its prevention and treatment corps diseases more particularly to a kind of fluorine-containing azoles ring bacterium amine.Its effective component is fluorine azoles ring bacterium amine, thifluzamide and pyraclostrobin, and three's weight ratio is 1~80:1~80:1~80, preferably 1~30:1~30:1~30.The bactericidal composition is made of the effective component of different role mechanism, and synergistic effect is obvious, resistance risk is small, wide sterilization spectrum, drug effect are long, at low cost, environmental pollution is small.

Description

A kind of bactericidal composition of fluorine-containing azoles ring bacterium amine and its application
Technical field
The present invention relates to technical field of pesticide compounding, a kind of bactericidal composition more particularly to fluorine-containing azoles ring bacterium amine and its The application for preventing and treating corps diseases.
Background technique
A kind of seed treatment fungicides of fluorine azoles Huan Junanshi Syngenta Co., Ltd exploitation, chemical name 2 '-[(1RS, 2RS) -1,1 '-connection cyclopropylene -2- base] -3- (difluoro), 1- methylpyrazole -4- carboxylic acid aniline is divided into cis and trans structure, English Literary adopted name: Sedaxane.Fluorine azoles ring bacterium amine is a kind of systemic fungicide, the eupnea mistake of energy suppression target pathogen Journey.It has good control efficiency to the head smut etc. on the crops such as corn, wheat, rice, soybean, cotton.The substance is low Poison when being used as seed coat agent, has preferable control efficiency to a variety of kinds of biographies, soil-borne diseases, may additionally facilitate the growth of crop root.
Seed coating technology refers to using sticker or film forming agent, with specific seed pelleting machine, by fungicide, desinsection The non-seed materials such as agent, micro- fertilizer, plant growth regulator, colorant or filler are wrapped in outside seed, with reach seed at Spherical shape keeps original shape substantially, improves resistance, disease resistance, accelerates germination, promotes seedling, and increase yield improves matter One seed technology of amount.The rapid film-forming of seed coat agent energy, thus it is not easily to fall off.Seed pelleting has been cited as China's emphasis and pushes away Wide agricultural technology project.Fungicide is made after seed coat agent is coated and is sowed, very to prevention and treatment soil-borne disease of crop effect Significantly.Novel seed treatment agent fluorine azoles ring bacterium amine of the invention is just being applicable in this dosage form.
Summary of the invention
The present invention is intended to provide a kind of bactericidal composition of fluorine-containing azoles ring bacterium amine, and it is made into that resistance risk is small, sterilization The agricultural double-crossed bactericidal composition that spectrum is wide, drug effect is long, at low cost, environmental pollution is small.
The technical solution of the present invention is as follows:
A kind of bactericidal composition of fluorine-containing azoles ring bacterium amine, effective ingredient are fluorine azoles ring bacterium amine, thifluzamide and pyrazoles ether Bacterium ester.
The weight ratio of the effective ingredient fluorine azoles ring bacterium amine, thifluzamide and pyraclostrobin be 1~80:1~80:1~ 80, preferably 1~30:1~30:1~30.
Above-mentioned effective ingredient fluorine azoles ring bacterium amine, thifluzamide and pyraclostrobin can be bought by various commercial channel.
In above-mentioned bactericidal composition, in addition to effective ingredient fluorine azoles ring bacterium amine, thifluzamide and pyraclostrobin, further include Agrotechnical formulation auxiliary ingredients.Effective ingredient fluorine azoles ring bacterium amine, thifluzamide and pyraclostrobin are shared in bactericidal composition Total weight percentage is 1%~90%, preferably 5%~80%.
The pesticidal preparations auxiliary ingredients include carrier and auxiliary agent.
The carrier is one of water, solvent or filler, two kinds or three kinds, the preferred deionized water of water.
The solvent is selected from N,N-dimethylformamide (DMF), cyclohexanone, toluene, dimethylbenzene, dimethyl sulfoxide, first Alcohol, ethyl alcohol, trimethylcyclohexanone, n-octylpyrrolidone, ethanol amine, triethanolamine, isopropylamine, N-Methyl pyrrolidone, One of propyl alcohol, butanol, ethylene glycol, diethylene glycol, ethylene glycol monomethyl ether, butyl ether, ethyl acetate or acetonitrile or a variety of compositions Mixture.
The filler is in kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or precipitated calcium carbonate The mixture of one or more compositions.
The auxiliary agent includes at least a kind of surfactant and can be also added antifreeze according to different use occasion and demand The other functions auxiliary agent such as agent, thickener, stabilizer, disintegrating agent, defoaming agent.
It is a variety of that the surfactant is selected from one of emulsifier, dispersing agent, wetting agent or bleeding agent.Above-mentioned surface is living Property agent be common nonionic surfactant or anionic surfactant single dose or compound preparation.
The other function auxiliary agent is one in antifreezing agent, thickener, stabilizer, film forming agent, disintegrating agent or defoaming agent Kind is a variety of.
The emulsifier is selected from agriculture breast 500# (alkyl benzene calcium sulfonate), OP series phosphate (nonylphenol polyoxyethylene ether phosphorus Acid esters), 600# phosphate (phenyl phenol polyoxyethylene ether phosphate), styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether Disulfonic acid magnesium salts, triethanolamine salt, agriculture breast 400# (benzyl dimethyl phenol polyoxyethyl ether), Nongru-700 # (alkylphenol formaldehyde tree Rouge polyoxyethyl ether), peaceful cream 36# (phenethyl phenol formaldehyde resin polyoxyethyl ether), agriculture breast 1600# (phenethyl phenol polyoxyethanyl Polypropylene-base ether), ethylene oxide-propylene oxide block copolymer, OP serial (nonylphenol polyoxyethylene ether), the serial (castor-oil plant of BY Oily polyoxyethylene ether), agriculture breast 33# (alkylaryl polyoxyethylene poly-oxygen propylene aether), Span series (sorbitol anhydride monostearate), One of TWEEN Series (anhydrous sorbitol resin acid ester APEO) or AEO serial (fatty alcohol polyoxyethylene ether) are more The mixture of kind composition.
The dispersing agent be selected from polycarboxylate, lignosulfonates, APES formaldehyde condensation products sulfat, Alkyl benzene calcium sulfonate, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkyl phenol polyoxyethylene ether, aliphatic amine polyoxyethylene ether, fatty acid polyglycol The mixture of one of ethylene oxide ether or glycerol fatty acid ester polyoxyethylene ethe or a variety of compositions.
The wetting agent is selected from lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, soap The mixture of one of angle powder, silkworm excrement or spaonin powder or a variety of compositions.
The bleeding agent is selected from penetrating agent JFC (fatty alcohol polyoxyethylene ether), penetrant t (diisooctyl maleate Sulfonate), the mixture of one of azone or organosilicon or a variety of compositions.
The antifreezing agent is selected from the mixture of one of ethylene glycol, propylene glycol, glycerine or urea or a variety of compositions.
The thickener be selected from one of xanthan gum, polyvinyl alcohol, bentonite, carboxymethyl cellulose or aluminium-magnesium silicate or The mixture of a variety of compositions.
The stabilizer is selected from one kind or more of epoxidized soybean oil, epoxychloropropane, BHT, ethyl acetate, triphenyl phosphate The mixture of kind composition.
The film forming agent selects CN-09.
The disintegrating agent is selected from bentonite, urea, ammonium sulfate, aluminium chloride, low-substituted hydroxypropyl cellulose, lactose, lemon The mixture of one of acid, succinic acid or sodium bicarbonate or a variety of compositions.
The defoaming agent is selected from silicone oil, silicone compound, C10~C20 saturated fat acids compound or C8~C10 rouge The mixture of one of fat alcohol compound or a variety of compositions.
Above-mentioned substance can be commercially available.
The dosage form agriculturally allowed can be prepared by known methods into bactericidal composition of the invention, and preferable dosage form is Wettable powder, suspoemulsion, suspension seed-coating agent, aqueous emulsion, microemulsion or water dispersible granules.
The present invention has following advantages:
1, expand fungicidal spectrum, not only to a variety of fungal diseases on crop, such as wheat, the smut of corn, cotton seedling The soil-borne diseases preventive effect such as sclerotiniose caused by phase samping off and various crop, damping-off is prominent, to crop banded sclerotial blight, white powder Disease, downy mildew, rust, anthracnose etc. also have preferable control efficiency；
2, synergistic effect is obvious, is not the simple superposition of each component activity, and drug effect greatly improves, and the field of effective ingredient is used Amount decline, reduces production and application cost, reduces pesticide residue and environmental pollution, to safety of human and livestock, Environmental compatibility is good；
3, prevention and treatment drug effect is high, and the lasting period is long, and resistance risk is small；
4, it is made of the effective ingredient of different role mechanism, action site increases, and is conducive to overcome and delay the anti-medicine of germ The generation of property.
Specific embodiment
The present invention is illustrated with reference to embodiments, but does not limit the invention to these specific embodiments.It is real It applies percentage in example to be weight percentage, the treatment dosage of field efficacy is preparation dosage.
One, embodiment is prepared
1, wettable powder
Preparation method: in Example formulations ratio, effective ingredient fluorine azoles ring bacterium amine, thifluzamide, pyraclostrobin are added Enter in carrier, and surfactant and other function auxiliary agent are added wherein, mixing remixes that be made can after air-flow crushing Wet powder.Capital equipment has mixing machine, airslide disintegrating mill.
Embodiment 1:(60% fluorine azoles ring bacterium amine thifluzamide pyraclostrobin wettable powder) 1:1:2
Formula: fluorine azoles ring bacterium amine, 15%；Thifluzamide, 15%；Pyraclostrobin, 30%；Wetting agent dodecyl sulphate Sodium, 2%；Dispersing agent calcium lignosulfonate, 8%；Filler white carbon black, 18%, filler kaolin, surplus.
2, water dispersible granules
Preparation method: in Example formulations ratio, effective ingredient fluorine azoles ring bacterium amine, thifluzamide and pyraclostrobin are added Enter in carrier, and surfactant and other function auxiliary agent are added wherein, mixing adds 10~25% after air-flow crushing Then water dispersible granules product is made through kneading, granulation, drying, screening in water；Or by the powder that crushed in boiling granulator Water spray is granulated, is dry, sieves product is made later.Capital equipment has mixing machine, airslide disintegrating mill, kneader, extrusion granulation Machine, drying chamber or fluidized bed drying or boiling granulator, screening machine.
Embodiment 2:(40% fluorine azoles ring bacterium amine thifluzamide pyraclostrobin water dispersible granule) 2:1:5
Formula: fluorine azoles ring bacterium amine, 10%；Thifluzamide, 5%；Pyraclostrobin, 25%；Dispersing agent Negel, 5%；Dispersing agent sodium lignin sulfonate, 7%；Wetting agent lauryl sodium sulfate, 2%；Urea (disintegrating agent) 5%, lightweight carbonic acid Calcium is mended, surplus.
3, suspension seed-coating agent
Preparation method: pressing formula rate, and effective ingredient fluorine azoles ring bacterium amine and thifluzamide, pyraclostrobin, surface are lived Property agent, film forming agent, dyestuff and other function auxiliary agent are sequentially placed into reaction kettle, are mixed with water, through high speed shear, wet process It is sanded, it is finally homogeneous to filter up to product.Capital equipment is batching kettle, colloid mill or homogeneous mixing machine, sand mill.
Embodiment 3:(14% fluorine azoles ring bacterium amine thifluzamide pyraclostrobin suspension seed-coating agent) 1:1:5
Formula: fluorine azoles ring bacterium amine, 2%；Thifluzamide, 2%；Pyraclostrobin, 10%；Wetting agent NP-10,1%；Poly- carboxylic Hydrochlorate dispersing agent, 3%；Thickener selects aluminium-magnesium silicate and xanthan gum, dosage are respectively 1.4% and 0.14%；Antifreezing agent is selected Propylene glycol, 5%；Film forming agent select CN-09,1.5%；Organically-modified silicone antifoam agent, 0.2%；Water, surplus.
4, aqueous emulsion
Preparation method: in Example formulations ratio by effective ingredient fluorine azoles ring bacterium amine, thifluzamide, pyraclostrobin with it is molten Agent, emulsifier, cosolvent are added together, and make to be dissolved into uniform oily phase；By part water, antifreeze, antimicrobial etc. other Insecticides adjuvant mix into uniform water phase；The oil phase is added to the aqueous phase while being stirred in the reactor at high speed, slowly Add water until reaching phase inversion point, open cutter and carry out high speed shear, and remaining water is added, shearing about half an hour, forms water The aqueous emulsion of oil-in.
Embodiment 4:(10% fluorine azoles ring bacterium amine thifluzamide pyraclostrobin aqueous emulsion) 1:1:3
Formula: fluorine azoles ring bacterium amine, 2%；Thifluzamide, 2%；Pyraclostrobin, 6%；Emulsifier select agriculture breast 500# and Agriculture breast 1601, dosage are respectively 2% and 4%；Solvent selection n,N-Dimethylformamide, 15%；Ethyl acetate, 10%；It is antifreeze Ethylene glycol, dosage 3% are selected in agent；Water, surplus.
5, microemulsion
Preparation method: in Example formulations ratio, effective ingredient fluorine azoles ring bacterium amine, thifluzamide, pyraclostrobin are used Solvent and cosolvent are completely dissolved, and then add other auxiliary agents, are uniformly mixed, are eventually adding water, after being sufficiently stirred, can make Obtain Pesticidal combination microemulsion formulation of the present invention.
Embodiment 5:(14% fluorine azoles ring bacterium amine thifluzamide microemulsion pyraclostrobin) 2:1:4
Formula: fluorine azoles ring bacterium amine, 4%；Thifluzamide, 2%；Pyraclostrobin, 8%；Solvent selects N, N- dimethyl methyl Amide and ethyl acetate, dosage are respectively 20% and 15%；Emulsifier selects agriculture breast 602# and agriculture breast 500#, dosage are respectively 9% and 6%；Water, surplus.
6, suspoemulsion
Preparation method: solvent, surfactant is added in effective ingredient pyraclostrobin in Example formulations ratio, adds water It is uniformly mixed, aqueous emulsion is made through high speed shear；Fluorine azoles ring bacterium amine, thifluzamide are added in carrier, and table are added wherein Face activating agent and other function auxiliary agent, are mixed with water, and through high speed shear, wet process is sanded, and suspending agent are made, finally by institute Obtained suspending agent and aqueous emulsion high speed shear, it is homogeneous to filter up to product.Capital equipment is batching kettle, colloid mill or homogeneous mixed Conjunction machine, sand mill.
Embodiment 10:(30% fluorine azoles ring bacterium amine thifluzamide pyraclostrobin suspoemulsion) 2:1:3
Formula: fluorine azoles ring bacterium amine, 10%；Thifluzamide, 5%；Pyraclostrobin, 15%；Solvents N-methyl pyrrolidines Ketone, dosage 25%；Emulsifier selects agriculture breast 500# and agriculture breast OP-10#, and dosage is respectively 4% and 5%；Oil dispersant polycarboxylic acids Salt, 8%；Thickener selects xanthan gum and aluminium-magnesium silicate, dosage are respectively 0.2% and 2.0%；Antifreeze glycol, dosage 3%；Water, surplus.
Two, BIOLOGICAL ACTIVITY EXAMPLES
BIOLOGICAL ACTIVITY EXAMPLES is divided into indoor biological activity Example and crop field BIOLOGICAL ACTIVITY EXAMPLES.
Active example 1: the indoor virulence that fluorine azoles ring bacterium amine, thifluzamide, pyraclostrobin compounding dissipate dust-brand to wheat is surveyed It is fixed
For the sprouting condition of Ustilago tritici, measured using plate spore rudiment method.
Band poison preparation of culture medium:
Quantitative reagent agent fluorine azoles ring bacterium amine, thifluzamide, pyraclostrobin are weighed respectively in 100mL specification volumetric flask In, appropriate DMF is added and is configured to raw medicine, the medical fluid of series of concentrations is made into after dilution.PDA culture medium is made, it is slightly cooling after sterilizing, The medical fluid prepared is added sufficiently to shake up, obtains the malicious culture medium of the band containing series of concentrations reagent agent.Every kind of medicament various concentration And control is respectively provided with the PDA plate that three diameters are 9cm and is used as repetition.
Spore suspension preparation:
Loose smut of wheat fringe is put into sterilized triangular flask and is sealed, shaking triangular flask makes conidia powder be scattered, and chooses It takes 4mg or so conidia powder to be put into 40mL sterile water, after sufficiently stirring evenly with filtered through gauze into sterilized triangular flask, obtains spore Sub- suspension.
Inoculation and culture:
0.1mL spore suspension is added dropwise in every ware on the PDA plate prepared, is smoothened with spatula, in microscope low-power field It is observed under (10 × 20), each visual field spore number is 100 or so.The PDA plate for being coated with spore suspension is placed on It is cultivated under 24 DEG C of dark conditions.
Observation and record:
Control spore germination situation is observed under the microscope every 6h, and in culture, control spore germination rate reaches most afterwards for 24 hours When big, observing each chemicals treatment miospore sprouting situation, (germ tube length formed with spore germination is considered as when being greater than spore radius Sprout), it calculates germination rate and does photograph record.Every ware PDA plate investigates three visuals field, amounts to 300 pieces of spores.
Calculation method:
Spore germination rate=(spore/300 of sprouting) × 100%
Mixture toxicity test and interpretation of result:
The toxicity test of mixture is carried out according to mixed ratio with single agent virulence determination method.
Inhibition percentage of each medicament to spore germination is looked into biometrics probit value conversion table and is converted into inhibition probit value, Using corresponding log concentration as abscissa x, inhibition probit value is ordinate y, finds out virulence regression equation and related coefficient, is calculated Median effective concentration EC of the reagent agent to Ustilago tritici out50, co-toxicity coefficient (CTC) is calculated according to Sun Yunpei method.Meter It is as follows to calculate formula: (using pyraclostrobin as standard agent, toxicity index 100):
Toxicity index (TI)=pyraclostrobin EC of thifluzamide50The EC of/thifluzamide50×100
Toxicity index (TI)=pyraclostrobin EC of fluorine azoles ring bacterium amine50The EC of/fluorine azoles ring bacterium amine50×100
True toxicity index (ATI)=pyraclostrobin EC of M50The EC of/M50×100
Theoretical toxicity index (TTI)=pyraclostrobin TI × P pyraclostrobin+thifluzamide TI × P thiophene furan of M Amide+fluorine azoles ring bacterium amine TI × P fluorine azoles ring bacterium amine
TTI × 100 of co-toxicity coefficient (CTC)=M ATI/M of M
In formula:
M is the mixture of pyraclostrobin, thifluzamide and fluorine azoles ring bacterium amine three's different ratio
P pyraclostrobin is pyraclostrobin ratio shared in mixture
P thifluzamide is thifluzamide ratio shared in mixture
P fluorine azoles ring bacterium amine is fluorine azoles ring bacterium amine ratio shared in mixture.
Criterion: co-toxicity coefficient < 80 is antagonism, is summation action between 80-120, and > 120 is synergy work With.
1 fluorine azoles ring bacterium amine of table, thifluzamide, pyraclostrobin compounding dissipate the The Toxicity Determination result of dust-brand to wheat
As it can be seen from table 1 the fluorine azoles ring bacterium amine of different proportion, thifluzamide, pyraclostrobin composition dissipate wheat The fungistatic effect of dust-brand pathogen is different, the experimental results showed that it is centainly than having synergistic effect in column range, wherein 1:1:5 and 2:1:5 proportion synergy is most significant.
Activity test 2: the field control effectiveness test of maize head smut is prevented and treated
According to " GB/T 17980.106-2004 pesticide field efficacy medicine test criterion (two) --- the sterilization of medicine inspecting institute, the Ministry of Agriculture The regulation of agent prevention and treatment maize head smut ", test medicine, comparison medicament and the processing of the cell of blank control are arranged using random district's groups Column, plot area 30m2~60m2, 4 repetitions.Insecticide-applying way is seed treatment, using seed pelleting, seed is made uniformly to be stained with medicine Agent.It is usually investigated after medicine 1 time, the obvious when progress of control time symptom after fruit ear all sprouts.Investigation method: outside every cell flash trimming row All investigation record total strain number, diseased plant number, calculate diseased plant rate, and record seedling-growing time and emergence rate.
Drug effect calculation method:
According to investigation result, diseased plant rate and preventive effect are calculated according to following (1), (2) formula.
Table 2 prevents and treats maize head smut field control effectiveness test result
As can be seen from Table 2,14% fluorine azoles ring bacterium amine thifluzamide pyraclostrobin FS is compounded with the ratio of 1:1:5 The significant effect for preventing and treating maize head smut is higher than single dose, and effect is incremented by with the increase of dosage.It is estimated according to field, in test agent It measures in range, plant growth is normal, and each treatment agent does not occur the phytotoxicity phenomenon to corn, to corn safety, for agricultural Volume increase is of great significance, and is worthy to be popularized.
Activity test 3: prevention and treatment cotton in seedling stage samping off field control effectiveness test
According to medicine inspecting institute, the Ministry of Agriculture " GB/T 17980.36-2000 pesticide field efficacy medicine test criterion (one) --- fungicide Seed treatment prevents and treats sprout term disease ", test medicine, comparison medicament and the processing of the cell of blank control are arranged using random district's groups, Plot area 30m2, 4 repetitions, insecticide-applying way is seed treatment, using seed pelleting, seed is made uniformly to be stained with medicament.Test Investigation result in two times investigates all cells for the first time and quantitatively sows capable emergence when the neat seedling of blank control cell.The Second survey blank control cell occurs investigating all cell sick seedling numbers when obvious symptom.Investigation method: each cell random five Sick seedling number is looked into point sampling, every 30 plants of investigation, investigates number of emerging and emergence date in quantitative sowing division.
Drug effect calculation method:
According to investigation result, emergence rate and preventive effect are calculated according to following (1), (2), (3) formula.
In formula: CK, PT are respectively blank district sick seedling rate, chemicals treatment district sick seedling rate.
Table 3 prevents and treats cotton in seedling stage samping off field control effectiveness test result
As can be seen from Table 3,14% fluorine azoles ring bacterium amine thifluzamide pyraclostrobin FS is compounded with the ratio of 1:1:5 Prevent and treat cotton in seedling stage samping off significant effect, when dosage all uses 40g/100kg seed, the significant effect of compound preparation It is the medicament of ideal prevention and treatment cotton in seedling stage samping off higher than single dose, and to cotton safety, and can effectively delays the anti-medicine of germ The generation of property.
Above-mentioned indoor biometrics and field control effectiveness test result show that the present invention contains fluorine azoles ring bacterium amine, thifluzamide and pyrazoles The bactericidal composition of kresoxim-methyl, to a variety of soil-borne diseases such as loose smut of wheat, maize head smut and cotton in seedling stage samping off There is good control efficiency, and it is without obvious harmful effects to trial crops, leaf color, growing way etc. are all normal, Target crops Safety.In conclusion bactericidal composition of the invention not only increases preventive effect compared with single dose, and it is by different role mechanism Effective ingredient composition, action site increase, be conducive to overcome and delay the generation of germ drug resistance, expand fungicidal spectrum, subtract Low drug cost, reduces environmental pollution and pesticide residue, so this compounded combination has highly important meaning in production practice Justice.

Claims (5)

1. a kind of bactericidal composition of fluorine-containing azoles ring bacterium amine, which is characterized in that effective component be fluorine azoles ring bacterium amine, thifluzamide and Pyraclostrobin, the weight ratio of the effective component fluorine azoles ring bacterium amine, thifluzamide and pyraclostrobin are 1~2:1:5~10.
2. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 1, which is characterized in that the effective component fluorine azoles Ring bacterium amine, thifluzamide and pyraclostrobin total weight percentage shared in bactericidal composition are 1%~90%, Remaining is auxiliary ingredients for pesticide preparations.
3. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 2, which is characterized in that the effective component fluorine azoles Ring bacterium amine, thifluzamide and pyraclostrobin total weight percentage shared in bactericidal composition are 5%~80%.
4. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to claim 2, which is characterized in that its dosage form be aqueous emulsion, One of microemulsion, suspension seed-coating agent, suspoemulsion, wettable powder or water dispersible granules.
5. the bactericidal composition of fluorine-containing azoles ring bacterium amine according to any one of claims 1-4 dissipates dust-brand in prevention and treatment wheat Application in disease, maize head smut and cotton in seedling stage samping off disease.
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CN101828560B (en) * 2010-06-02 2013-03-27 陕西上格之路生物科学有限公司 Agricultural sterilizing composite containing thifluzamide
CN104719298A (en) * 2013-12-20 2015-06-24 陕西美邦农药有限公司 Bactericidal composition containing sedaxane
CN104719297A (en) * 2013-12-20 2015-06-24 陕西美邦农药有限公司 Sterilization composition containing sedaxane and methoxy acrylate

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CN101828560B (en) * 2010-06-02 2013-03-27 陕西上格之路生物科学有限公司 Agricultural sterilizing composite containing thifluzamide
CN104719298A (en) * 2013-12-20 2015-06-24 陕西美邦农药有限公司 Bactericidal composition containing sedaxane
CN104719297A (en) * 2013-12-20 2015-06-24 陕西美邦农药有限公司 Sterilization composition containing sedaxane and methoxy acrylate

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