CN106770756A - 通过质谱分析法检测双氢睾酮的方法 - Google Patents

通过质谱分析法检测双氢睾酮的方法 Download PDF

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Publication number
CN106770756A
CN106770756A CN201611163981.7A CN201611163981A CN106770756A CN 106770756 A CN106770756 A CN 106770756A CN 201611163981 A CN201611163981 A CN 201611163981A CN 106770756 A CN106770756 A CN 106770756A
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CN
China
Prior art keywords
dht
ion
sample
method described
mass spectrometry
Prior art date
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Pending
Application number
CN201611163981.7A
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English (en)
Chinese (zh)
Inventor
A·戈沙尔
N·J·克拉克
R·瑞茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quest Diagnostics Investments LLC
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Quest Diagnostics Investments LLC
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42075045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN106770756(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Quest Diagnostics Investments LLC filed Critical Quest Diagnostics Investments LLC
Publication of CN106770756A publication Critical patent/CN106770756A/zh
Pending legal-status Critical Current

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Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201611163981.7A 2008-10-06 2009-09-30 通过质谱分析法检测双氢睾酮的方法 Pending CN106770756A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10320208P 2008-10-06 2008-10-06
US61/103,202 2008-10-06
US12/272,663 2008-11-17
US12/272,663 US7804063B2 (en) 2008-10-06 2008-11-17 Methods for detecting dihydrotestosterone by mass spectrometry
CN2009801488128A CN102239266A (zh) 2008-10-06 2009-09-30 通过质谱分析法检测双氢睾酮的方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2009801488128A Division CN102239266A (zh) 2008-10-06 2009-09-30 通过质谱分析法检测双氢睾酮的方法

Publications (1)

Publication Number Publication Date
CN106770756A true CN106770756A (zh) 2017-05-31

Family

ID=42075045

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2009801488128A Pending CN102239266A (zh) 2008-10-06 2009-09-30 通过质谱分析法检测双氢睾酮的方法
CN201611163981.7A Pending CN106770756A (zh) 2008-10-06 2009-09-30 通过质谱分析法检测双氢睾酮的方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN2009801488128A Pending CN102239266A (zh) 2008-10-06 2009-09-30 通过质谱分析法检测双氢睾酮的方法

Country Status (9)

Country Link
US (4) US7804063B2 (enExample)
EP (2) EP2344661B1 (enExample)
JP (2) JP6096412B2 (enExample)
CN (2) CN102239266A (enExample)
AU (1) AU2009302641B2 (enExample)
BR (1) BRPI0920028A8 (enExample)
CA (1) CA2739506C (enExample)
MX (1) MX2011003653A (enExample)
WO (1) WO2010042370A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7893399B2 (en) * 2008-09-09 2011-02-22 Quest Diagnostics Investments Incorporated Methods for detecting dehydroepiandrosterone by mass spectrometry
US7804063B2 (en) * 2008-10-06 2010-09-28 Quest Diagnostics Investments Incorporated Methods for detecting dihydrotestosterone by mass spectrometry
US8153962B2 (en) 2008-12-24 2012-04-10 Quest Diagnostics Investments Incorporated Mass spectrometry assay for congenital adrenal hyperplasia
US9834578B2 (en) * 2010-05-27 2017-12-05 University Of Utah Research Foundation Enhanced sensitivity for analysis of ketosteroid compounds using mass spectrometry
SG192661A1 (en) * 2011-02-07 2013-09-30 Lab Corp America Holdings Methods and systems for determining the presence or amount of testosterone in a sample
JP2015503753A (ja) * 2012-01-05 2015-02-02 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド ケトステロイドとケトまたはアルデヒドを含む分析物との敏感度および特異度の強化
CN107525857B (zh) * 2017-03-29 2019-11-12 中国检验检疫科学研究院 一种洗护用品中孕激素化学风险物质的筛查方法
CN107064400B (zh) * 2017-04-20 2018-09-21 博厚健康科技股份有限公司 同时检测血清中五种类固醇激素的方法
CN109633041B (zh) * 2019-02-26 2021-07-02 广东食品药品职业学院 衍生化hplc法测定药物中双氢睾酮的方法
US11536733B2 (en) * 2019-04-16 2022-12-27 Laboratory Corporation Of America Holdings Methods and systems for the detection of 11-oxo androgens by LC-MS/MS
KR102046488B1 (ko) * 2019-07-02 2019-11-19 건국대학교 글로컬산학협력단 모유은행 기증 모유의 다차원 분석방법

Citations (1)

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Publication number Priority date Publication date Assignee Title
US6977143B1 (en) * 2003-09-08 2005-12-20 Quest Diagnostics Investments Incorporated Determination of testosterone by mass spectrometry

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US8016A (en) * 1851-04-01 Improvement in the manufacture of india-rubber
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
ATE242485T1 (de) * 1993-05-28 2003-06-15 Baylor College Medicine Verfahren und massenspektrometer zur desorption und ionisierung von analyten
US5772874A (en) * 1995-11-02 1998-06-30 Cohesive Technologies, Inc. High performance liquid chromatography method and apparatus
AU712735B2 (en) * 1996-01-19 1999-11-11 Cohesive Technologies, Inc. High performance liquid chromatography method and apparatus
GB9717926D0 (en) * 1997-08-22 1997-10-29 Micromass Ltd Methods and apparatus for tandem mass spectrometry
EP1050065A4 (en) * 1998-01-23 2004-03-31 Analytica Of Branford Inc SURFACES MASS
AU4299301A (en) * 2000-02-29 2001-09-12 National University Of Singapore, The A method for modulating steroidogenic activity
WO2003012445A1 (en) * 2001-07-30 2003-02-13 Quest Diagnostics Investments Incorporated Methods and kits for detecting ita in a biological sample
JP3774888B2 (ja) * 2001-11-28 2006-05-17 日本化薬株式会社 ステロイド類化合物のｌｃ−ｍｓによる高感度検出法
US20040033530A1 (en) * 2002-04-08 2004-02-19 Awrey Donald E. High throughput purification, characterization and identification of recombinant proteins
JP3686657B2 (ja) * 2003-02-27 2005-08-24 帝国臓器製薬株式会社 ステロイド性生体内微量物質の測定方法
EP1756101A2 (en) * 2004-05-17 2007-02-28 Acadia Pharmaceuticals Inc. Androgen receptor modulators and method of treating disease using the same
CA2654319C (en) * 2006-05-26 2014-08-12 Laboratory Corporation Of America Holdings Liquid chromatography with tandem mass spectrometry of estrone, estradiol and free thyroxine
US20080176269A1 (en) * 2006-10-06 2008-07-24 Mohler James L Method for determination of DHT levels in tissue samples
JP3141511U (ja) * 2008-02-22 2008-05-08 株式会社島津製作所 液体クロマトグラフ質量分析装置
US7893399B2 (en) * 2008-09-09 2011-02-22 Quest Diagnostics Investments Incorporated Methods for detecting dehydroepiandrosterone by mass spectrometry
US7804063B2 (en) * 2008-10-06 2010-09-28 Quest Diagnostics Investments Incorporated Methods for detecting dihydrotestosterone by mass spectrometry
US8153962B2 (en) * 2008-12-24 2012-04-10 Quest Diagnostics Investments Incorporated Mass spectrometry assay for congenital adrenal hyperplasia

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6977143B1 (en) * 2003-09-08 2005-12-20 Quest Diagnostics Investments Incorporated Determination of testosterone by mass spectrometry
US20080166697A1 (en) * 2003-09-08 2008-07-10 Quest Diagnostics Investments Incorporated Determination of testosterone by mass spectrometry

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ATSUSHI YAMAMOTO等人: "Steroid Hormone Profiles of Urbanand Tidal Rivers Using LC/MS/MS Equipped with Electrospray Ionization and Atmospheric Pressure Photoionization Sources", 《ENVIRON.SCI.TECHNOL.》 *
STEVE SHIRAISHI等人: "Simultaneous Measurement of Serum Testosterone and Dihydrotestosterone by Liquid Chromatography-Tandem Mass Spectrometry", 《CLINICAL CHEMISTRY》 *

Also Published As

Publication number Publication date
US20110006197A1 (en) 2011-01-13
EP3124617A1 (en) 2017-02-01
JP6096412B2 (ja) 2017-03-15
US20120175517A1 (en) 2012-07-12
US8410428B2 (en) 2013-04-02
US7804063B2 (en) 2010-09-28
EP2344661B1 (en) 2019-02-20
US8563922B2 (en) 2013-10-22
JP2012504766A (ja) 2012-02-23
AU2009302641A1 (en) 2010-04-15
CN102239266A (zh) 2011-11-09
AU2009302641B2 (en) 2015-05-21
CA2739506A1 (en) 2010-04-15
MX2011003653A (es) 2011-09-06
US20100084546A1 (en) 2010-04-08
US20130228680A1 (en) 2013-09-05
BRPI0920028A8 (pt) 2017-11-21
JP6151291B2 (ja) 2017-06-21
CA2739506C (en) 2019-02-12
US8158931B2 (en) 2012-04-17
WO2010042370A1 (en) 2010-04-15
JP2015143699A (ja) 2015-08-06
EP2344661A1 (en) 2011-07-20
EP2344661A4 (en) 2012-08-01
BRPI0920028A2 (pt) 2015-12-15

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