CN106730340A - The system that a kind of chargeable implantable medical device cooperates - Google Patents
The system that a kind of chargeable implantable medical device cooperates Download PDFInfo
- Publication number
- CN106730340A CN106730340A CN201611267926.2A CN201611267926A CN106730340A CN 106730340 A CN106730340 A CN 106730340A CN 201611267926 A CN201611267926 A CN 201611267926A CN 106730340 A CN106730340 A CN 106730340A
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- subsystem
- module
- sacral nerve
- nerve stimulation
- communication module
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36135—Control systems using physiological parameters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/375—Constructional arrangements, e.g. casings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/378—Electrical supply
Abstract
The invention discloses the system that a kind of chargeable implantable medical device cooperates, including sacral nerve stimulation subsystem, muscular irritation subsystem, a sensor subsystem and an external telemetry equipment;Sacral nerve stimulation subsystem includes sacral nerve stimulation electrode, pulse generator module, processor module, wake module, communication module;Muscular irritation subsystem includes muscle stimulation electrodes, muscular irritation pulse generator module, processor module, wake module, communication module;Wherein, implant system has charge coil, main battery and reserve battery;Charge coil and reserve battery all charge to main battery.The electric energy of the system that Medical Devices cooperate quickly is supplemented by such charging system.
Description
Technical field
System the present invention relates to there is multiple implantable medical equipment, in particular to a kind of chargeable implantable medical equipment
The system of collaborative work.
Background technology
Muscular irritation is more and more used for the diseases such as treatment chronic ache, urination dysporia.With entering for technology
Step sacral nerve stimulation is also used to the diseases such as treatment urination dysporia.
Method in the prior art by muscular irritation or the sacral nerve stimulation treatment urinary incontinence is single, and therapeutic effect has
Limit.Such as, can be caused with the growth of stimulation time " muscular fatigue " by the muscle stimulation treatment urinary incontinence, under making therapeutic effect
Drop;And the urinary incontinence is treated from therapeutic effect by sacral nerve stimulation, success rate need further raising.
United States Patent (USP) US7384390B2 discloses a kind of method and apparatus for treating the urinary incontinence, the method pulse generation
The stimulus signal that device is produced reaches the purpose of the treatment urinary incontinence by the sphincter of electrode stimulating Periurethral.United States Patent (USP)
US7328069B2 discloses a kind of method and apparatus, for the medicine that conveying is associated for one or more with electronic stimulation, produces
Raw one or more electrical stimulation signals are used to stimulate pelvis bottom and/or the sacral nerve of private parts of patient, for treating including but not
It is confined to, homaluria dysfunction, excrement excretory function obstacle, constipation, stress incontinence urges incontinence, retention of urine obstacle, property work(
The diseases such as energy obstacle, climax dysfunction, erectile dysfunction, pelvic pain, prostatitis, prostatodynia.
Have that the method for treating the urinary incontinence by muscular irritation or sacral nerve stimulation in technology is single, therapeutic effect is limited.
Can be caused with the growth of stimulation time " muscular fatigue " by the muscle stimulation treatment urinary incontinence, decline therapeutic effect;And
The urinary incontinence is only treated from therapeutic effect by sacral nerve stimulation, success rate need further raising.
The present invention is carried out soon by the system of the chargeable implantable medical equipment collaboration work implant system big to power consumption
Speed charges.
The content of the invention
It is an object of the invention in overcoming the shortcomings of above-mentioned technology, there is provided a kind of chargeable implantable medical device association
With the system of work, including sacral nerve stimulation subsystem, muscular irritation subsystem, a sensor subsystem and a body
Outer remote-measuring equipment;Described sacral nerve stimulation subsystem includes sacral nerve stimulation electrode, the first pulse generator module, at first
It is reason device module, the first wake module, first communication module, the first charge coil, at least one first main battery, at least one first standby
Use battery;First processor module controls the first charge coil at least one first main battery and at least one first reserve battery fills
Electricity;First processor module controls at least one first reserve battery to be charged at least one first main battery.
Described muscular irritation subsystem includes muscle stimulation electrodes, muscular irritation pulse generator module, second processing
It is device module, the second wake module, second communication module, the second charge coil, at least one second main battery, at least one second standby
Battery;Second processing device module controls the second charge coil at least one second main battery and at least one second reserve battery fills
Electricity;Second processing device module controls at least one second reserve battery to be charged at least one second main battery.
Described sensor subsystem includes pressure sensor, the 3rd processor module and third communication module;Described
External telemetry equipment includes fourth processor module, fourth communication module and display module;Sacral nerve stimulation electrode is implanted to trouble
Around the sacral nerve of person's waist bottom, muscle stimulation electrodes are implanted to around patient's sphincter urethrae, pressure sensor detection bladder
Pressure;External telemetry equipment opens sacral nerve stimulation system or muscle stimulation system with default stimulation by fourth communication module
Parameter stimulates relevant position, if opening sacral nerve stimulation system, first processor module controls the first impulse generator with first
After default stimulation parameter stimulates the first Preset Time, sacral nerve stimulation system is led to by first communication module with second communication module
Letter, the second wake module wakes up second processing device module, sacral nerve stimulation system dormancy of working together, second processing device module control the
After two impulse generators stimulate the Preset Time of sphincter second with the second parameter preset, then sacral nerve stimulation system is waken up, stimulated
During pressure sensor detection bladder pressure, processor judges bladder pressure when being more than predetermined threshold value then by third communication mould
Block notifies that the current stimulating system for being stimulated enters park mode, waits the control of external telemetry equipment to be stimulated again afterwards.
Further, the communication module of sacral nerve stimulation subsystem, muscular irritation subsystem, sensor subsystem and external telemetry equipment
Between can carry out RFDC;The communication of sacral nerve stimulation subsystem, muscular irritation subsystem and sensor subsystem
Module individually can carry out bidirectional wireless data communication with external telemetry equipment;External telemetry equipment can be by communication module
Sacral nerve stimulation subsystem and muscular irritation subsystem are programmed respectively, can be by the manual startup of external telemetry equipment
Or sacral nerve stimulation subsystem, muscular irritation subsystem and sensor subsystem are closed, sacral nerve stimulation subsystem can also be shown
The mode of operation and the detected pressure value of sensor subsystem of system and muscular irritation subsystem.It is currently preferred for treating
The urinary incontinence, can be also used for treatment and includes, but are not limited to, faecal incontinence, homaluria dysfunction, excrement excretory function barrier
Hinder, stress incontinence urges incontinence, retention of urine obstacle, sex dysfunction, pelvic pain, prostatitis, the disease such as prostatodynia.
Brief description of the drawings
Fig. 1 is the system diagram that chargeable implantable medical device of the invention cooperates.
Specific embodiment
The present invention is further described with reference to the accompanying drawings and examples.
Fig. 1 shows the relevant physiological anatomical structure figure of patient 100, and the characteristic physiological anatomical structure of patient 100 includes wing
Guang 101, urethra 102, sphincter urethrae 103 and sacral nerve 104.Sacral nerve rootses provide bladder, urethra, the body of advocating peace certainly at basin bottom
Somatic nerves is arranged, therefore, sacral nerve neuromodulation is by excited or suppress these nerve roots and can reach treatment low urinary tract function obstacle disease
The purpose of trouble.The random contraction of verified basin bottom and external sphincter can eliminate the unstable contraction of bladder, stimulate S3 or S4
Nerve root can cause basin bottom and the incorrect of the enhancing of sphincter strength, correction basin bottom and urethra to relax, and then prevent or reduce
The unstable contraction of detrusor, with continued reference to Figure of description 1, the chargeable implantable medical device collaboration work in the present invention
The system of work, mainly includes a sensor subsystem of muscular irritation subsystem 400, of sacral nerve stimulation subsystem 300,
System 200 and external telemetry equipment 500.User can be by external telemetry equipment 500 to sacral nerve stimulation subsystem 300, muscle
Subsystem 400, sensor subsystem 200 is stimulated to send control instruction, so as to realize between above-mentioned several implantable medical devices
Collaborative work.
Described sacral nerve stimulation subsystem 300 includes sacral nerve stimulation electrode 303, the first pulse generator module, the
One processor module, the first wake module, first communication module, the first charge coil, at least one first main battery, at least 1
One reserve battery.Described sacral nerve stimulation electrode 303 is connected to sacral nerve stimulator 301 by extension lead 302.Sacral nerve
The end of stimulating electrode 303 is provided with the stimulation point for being contacted with sacral nerve 104, can cause electricity by fixed or clamping device
Pole end keeps good contact with sacral nerve 104.Stimulating electrode design must is fulfilled for the condition that can be chronically implanted, i.e., nontoxic, most
Few foreign body reaction, histocompatbility is good etc., and should avoid interference of the stimulating current to surrounding tissue.Comprehensive each side because
Element, stimulating electrode shape may be configured as annular shape, helical form, semi-cylindrical shape or any one hook-shaped, the He of extension lead 302
The material of sacral nerve stimulation electrode 303 can be silver, platinumiridio, nickel, nickel alloy;The overcoat medical high polymer of extension lead 302
Insulation tube, medical macromolecular materials are preferably the flexible high molecular materials such as nylon, polyurethane, polytetrafluoroethylene (PTFE).At described first
Reason device module controls first charge coil to be filled at least one first main battery and at least one first reserve battery
Electricity;At least one first reserve battery described in the first processor module control charges at least one first main battery.
Described muscular irritation subsystem 400 includes muscle stimulation electrodes 403, muscular irritation pulse generator module, the
Two processor modules, the second wake module, second communication module, the second charge coil, at least one second main battery, at least 1
Two reserve batteries.Described muscle stimulation electrodes 403 are connected to muscle stimulator 401 by extension lead 402.Sacrum muscular irritation
The end of electrode 403 is provided with the stimulation point for being contacted with sphincter urethrae 103, can cause electricity by fixed or clamping device
Pole end keeps good contact with sphincter urethrae 103.Muscle stimulation electrodes are preferably the wire electrode of flexibility, about 1-5
Millimeter it is long and a diameter of 50-100 micron, be so configured so that patient discomfort minimum.They lead to
Often formed with spirality as known in the art or hook-type, so they easily and can be permanently anchored to intramuscular.System
Wire into electrode is made up of suitable conductive of material, preferably the metal of bio-compatible, such as silver, platinum/iridium alloy
Or ni cr alloy (90/10).Extension lead is surrounded by insulating sheath, and above-mentioned sheath specifically includes nylon, polyurethane, poly- four
The bio-compatible insulating materials of PVF or other compliances.The second processing device module controls second charge coil to give
At least one second main battery and at least one second reserve battery charge;Described in the second processing device module control extremely
Few one second reserve battery charges at least one second main battery.
Described sensor subsystem 200 includes pressure sensor, the 3rd processor module and third communication module.Pressure
Sensor arrangement in bladder, by detecting that pressure signal therein changes to measure intravesical pressure.In order to meet implantation
Of the invention use is needed, and pressure sensor dimensionally very little must be passed to be easily implanted into and to minimize to surrounding pressure
The interference of the organizational environment of sensor, and they must using radio communication from without line, conduit or need it is percutaneous
Other parts of passage.They must be formed to minimize patient couple by Resisting fractre, nontoxic and permanent biocompatible materials
The immune response of the introducing of foreign matter and prevent the tissue damage caused by corrosion by-products.The pressure sensor of implantation must provide for
Reliable pressure value is kept so that the decision for the treatment of can surely be made in the useful life of sensor, to avoid for tune
The outside implantation of the sensor of whole purpose.Pressure sensor is preferably MEMS(MEMS)Sensor.
Processor in sacral nerve stimulation subsystem 300, muscular irritation subsystem 400, sensor subsystem 200 is typically adopted
With embedded microprocessor, from high integration low-power scm, with various energy-saving modes, storage is internally integrated at it
Device, analog-to-digital conversion ADC and digital-to-analogue conversion DAC, and support that self-programming is operated, short-range communications module includes wireless communication module,
Communication protocol can be according to physical condition using the short distance wireless technical such as Zigbee, bluetooth, infrared.The main battery and described standby
It is Li-Ion rechargeable battery with battery.
Described external telemetry equipment 500 includes fourth processor module, fourth communication module and display module.It is external distant
Measurement equipment 500 is arranged on patient 100 in vitro, for carrying out radio communication with implantable medical formula equipment, so as to realize data acquisition
The functions such as transmission, control and maintenance implantable medical device work, external telemetry equipment is preferably palm PC, individual digital and helps
Reason(PDA)Or the form of smart mobile phone.
The main battery and the reserve battery are Li-Ion rechargeable battery.
As shown in Figure 1, sacral nerve stimulation electrode 303 is implanted to around the sacral nerve 104 of the waist bottom of patient 100, muscle
Stimulating electrode 403 is implanted to around the sphincter urethrae 103 of patient 100, and bladder pressure is detected using pressure sensor;External telemetry
Equipment 500 opens sacral nerve stimulation subsystem 300 or muscular irritation subsystem 400 with default stimulation by fourth communication module
Parameter stimulates relevant position.If opening sacral nerve stimulation subsystem 300, first processor module control the first impulse generator with
After first default stimulation parameter stimulates the first Preset Time, sacral nerve stimulation subsystem 300 passes through first communication module and second
Communication module communicates, and the second wake module wakes up second processing device module, while the dormancy of sacral nerve stimulation system 300;At second
After reason device module control muscular irritation impulse generator stimulates the Preset Time of sphincter second with the second parameter preset, muscular irritation
Subsystem 400 is communicated by second communication module with first communication module, the first wake module wake up first processor module from
And sacral nerve stimulation subsystem 400 is waken up, while the dormancy of muscular irritation subsystem 400.Sacral nerve stimulation subsystem 300 and flesh
Corn exciton system 400 is according to sequence described above alternately and repeatedly to correspondingly being stimulated around sacral nerve and sphincter urethrae.
In stimulating course, the pressure sensor real-time detection bladder pressure in sensor subsystem 200, the 3rd processor judges bladder pressure
Whether power is more than predetermined threshold value, if bladder pressure is more than predetermined threshold value, notifies currently to be stimulated by third communication module
Stimulating system enter park mode, wait the control instruction of external telemetry equipment 500 to perform corresponding stimulation applications again afterwards.
Arousal function generally comprises the function of being operated with high-power mode only during special time, the special time example
The short cycle for (for example, receiving signal) such as a specific purpose.The important consideration of the receiver part on wake module
It is that it has low-power.This feature may be conducive to provide small size in implanted receiver and maintain from battery
Longtime running power supply.In practice, the receiver of wake module periodically " can wake up " and in low energy consumption so as to
Performed via such as monitoring circuit " monitor function ".For the application, term " monitor function " is generally referred to as being used for
Determine whether there is the short low power function of transmitter.If monitor function detects launcher signal, the equipment can be with
It is converted to higher-wattage communication decoding schema.If there is no launcher signal, then receiver can be returned and for example returned immediately
To park mode.In this way, energy is saved during the relative long periods in the absence of launcher signal, and is believed there is transmission
Number the relatively little of period during make power capabilities keep can be used for efficient decoding schema operating.
Sacral nerve stimulation subsystem 300, muscular irritation subsystem 400, sensor subsystem 200 and external telemetry equipment
RFDC can be carried out between 500 communication module;Preferably, sacral nerve stimulation subsystem 300, muscular irritation subsystem
The communication module of system 400 and sensor subsystem 200 can individually carry out bidirectional wireless data with external telemetry equipment 500 and lead to
Letter.The communication module includes wireless communication module, and communication protocol can be according to physical condition using Zigbee, bluetooth, infrared etc.
Short distance wireless technical.
External telemetry equipment 500 can be by communication module respectively to sacral nerve stimulation subsystem 300 and muscular irritation
System 400 is programmed, so as to sacral nerve stimulation subsystem 300, muscular irritation subsystem 400 and sensor subsystem 200
Send corresponding control instruction.By the manual startup of external telemetry equipment 500 or sacral nerve stimulation subsystem can be closed
300th, muscular irritation subsystem 400 and sensor subsystem 200, can also show sacral nerve stimulation subsystem on display module
300 and the pressure of the mode of operation of muscular irritation subsystem 400, working condition, electrode stimulating parameter and sensor subsystem 200
Power detected value.
The description of foregoing embodiment and preferred embodiment should be regarded as the explanation of the claims in the present invention, rather than
It is defined.It is appreciated that under the premise of without departing substantially from the present invention as claimed in claim, it is possible to use features described above
Many combinations and variant, this kind of variant do not run counter to the spirit and scope of the present invention, and all these variants are intended to be included in following
The scope of claim.
Claims (5)
1. the system that a kind of chargeable implantable medical device cooperates, it is characterised in that:The system includes a sacrum god
Through stimulating subsystem(300), a muscular irritation subsystem(400), a sensor subsystem(200)With external telemetry equipment
(500);Described sacral nerve stimulation subsystem(300)Including sacral nerve stimulation electrode(303), the first pulse generator module,
First processor module, the first wake module, first communication module, the first charge coil, at least one first main battery, at least one
First reserve battery;Described muscular irritation subsystem(400)Including muscle stimulation electrodes(403), muscular irritation pulse generation
Device module, second processing device module, the second wake module, second communication module, at least the second charge coil, one second main electricity
Pond, at least one second reserve battery;Described sensor subsystem(200)Including pressure sensor, the 3rd processor module and
Third communication module;Described external telemetry equipment(500)Including fourth processor module, fourth communication module and display mould
Block;The first processor module controls first charge coil at least one first main battery and described at least 1 the
One reserve battery charges;At least one first reserve battery is at least one first master described in the first processor module control
Battery charges;The second processing device module control second charge coil at least one second main battery and it is described extremely
Few one second reserve battery charges;At least one second reserve battery is to described at least one described in the second processing device module control
Second main battery charges.
2. the system that chargeable implantable medical device according to claim 1 cooperates, it is characterised in that:It is described
Sacral nerve stimulation electrode(303)It is implanted to around the sacral nerve of patient's waist bottom, the muscle stimulation electrodes(403)It is implanted to trouble
Around person's sphincter urethrae, bladder pressure is detected by the pressure sensor;The external telemetry equipment(500)By four-way
Letter module opens the sacral nerve stimulation subsystem(300)Or the muscular irritation subsystem(400)With default stimulation parameter
Stimulate relevant position, if opening the sacral nerve stimulation subsystem(300), first processor module the first impulse generator of control
With the sacral nerve stimulation subsystem after first the first Preset Time of default stimulation parameter stimulation(300)By first communication module
Communicated with second communication module, the second wake module wakes up second processing device module, while the sacral nerve stimulation subsystem
(300)Dormancy, when second processing device module controls the second impulse generator to be preset with the second parameter preset stimulation sphincter second
Between after, then wake up the sacral nerve stimulation subsystem(300), the detection bladder pressure of pressure sensor described in stimulating course, institute
State processor and judge that bladder pressure then notifies the current thorn for being stimulated when being more than predetermined threshold value by the third communication module
Exciton system enters park mode, and the external telemetry equipment is waited afterwards(500)Control is stimulated again.
3. the system that chargeable implantable medical device according to claim 1 cooperates, it is characterised in that:It is described
Sacral nerve stimulation subsystem(300), the muscular irritation subsystem(400), the sensor subsystem(200)It is external with described
Remote-measuring equipment(500)Communication module between can carry out RFDC;The sacral nerve stimulation subsystem, the muscle
Stimulate subsystem(400)With the sensor subsystem(200)Communication module can individually with the external telemetry equipment
(500)Carry out bidirectional wireless data communication;The external telemetry equipment(500)Can be by communication module respectively to sacrum god
Through stimulating subsystem(300)With the muscular irritation subsystem(400)Data input is carried out, can be by the external telemetry equipment
(500)Manual startup or the closing sacral nerve stimulation subsystem(300), the muscular irritation subsystem(400)With it is described
Sensor subsystem(200).
4. the system that chargeable multiple implantable medical devices according to claim 1 cooperate, it is characterised in that:
The system that the plurality of implantable medical device cooperates may also display the sacral nerve stimulation subsystem, muscular irritation
System(400)Mode of operation and the sensor subsystem(200)Detected pressure value.
5. the system that chargeable multiple implantable medical devices according to claim 1 cooperate, it is characterised in that:
The main battery and the reserve battery are Li-Ion rechargeable battery.
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CN201611267926.2A CN106730340A (en) | 2016-12-31 | 2016-12-31 | The system that a kind of chargeable implantable medical device cooperates |
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CN201611267926.2A CN106730340A (en) | 2016-12-31 | 2016-12-31 | The system that a kind of chargeable implantable medical device cooperates |
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Cited By (1)
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CN107802936A (en) * | 2017-10-26 | 2018-03-16 | 山东大学 | A kind of exhaled positive pressure nasal mask with nerve stimulation function |
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EP2478935A2 (en) * | 2011-01-21 | 2012-07-25 | NeuroCardiac Innovations, LLC | Implantable cardiac devices with body orientation unit |
CN103079633A (en) * | 2010-03-11 | 2013-05-01 | 梅恩斯塔伊医疗公司 | Modular stimulator for treatment of back pain, implantable RF ablation system and methods of use |
CN103170060A (en) * | 2013-01-18 | 2013-06-26 | 郑曙云 | Intelligentized bladder urinary function controller |
CN105555359A (en) * | 2013-10-04 | 2016-05-04 | 波士顿科学神经调制公司 | Implantable medical device with a primary and rechargeable battery |
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US20090054950A1 (en) * | 2005-03-02 | 2009-02-26 | Continence Control Systems International Pyt Ltd. | Method and Apparatus for Treating Incontinence |
CN103079633A (en) * | 2010-03-11 | 2013-05-01 | 梅恩斯塔伊医疗公司 | Modular stimulator for treatment of back pain, implantable RF ablation system and methods of use |
EP2478935A2 (en) * | 2011-01-21 | 2012-07-25 | NeuroCardiac Innovations, LLC | Implantable cardiac devices with body orientation unit |
CN103170060A (en) * | 2013-01-18 | 2013-06-26 | 郑曙云 | Intelligentized bladder urinary function controller |
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Application publication date: 20170531 |