CN106730102B - Lower respiratory tract lavage device - Google Patents

Lower respiratory tract lavage device Download PDF

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Publication number
CN106730102B
CN106730102B CN201710046062.XA CN201710046062A CN106730102B CN 106730102 B CN106730102 B CN 106730102B CN 201710046062 A CN201710046062 A CN 201710046062A CN 106730102 B CN106730102 B CN 106730102B
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CN
China
Prior art keywords
guide member
lavage
respiratory tract
lower respiratory
container
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Active
Application number
CN201710046062.XA
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Chinese (zh)
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CN106730102A (en
Inventor
闫崴
田兆兴
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Peking University Third Hospital
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Peking University Third Hospital
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Priority to CN201710046062.XA priority Critical patent/CN106730102B/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0279Cannula; Nozzles; Tips; their connection means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M3/00Medical syringes, e.g. enemata; Irrigators
    • A61M3/02Enemata; Irrigators
    • A61M3/0279Cannula; Nozzles; Tips; their connection means
    • A61M3/0287Cannula; Nozzles; Tips; their connection means with an external liquid collector
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1035Bronchi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1039Lungs

Abstract

The lower respiratory tract lavage device of the present invention comprises: a guide member having a generally cylindrical tube shape and having a proximal end adjacent to an operator and a distal end for extending into the lower respiratory tract, the guide member having an lavage fluid introduction portion on the proximal end for introducing lavage fluid into the guide member for guiding by the guide member to a target site to be lavaged; a sealing member disposed near the distal end of the guide member for forming a seal between an outer wall of the guide member and an inner wall of a target site in the lower respiratory tract when the guide member is extended into the target site in the lower respiratory tract; and an lavage fluid collection member disposed proximate the proximal end of the guide member for collecting lavage fluid after lavage, the guide member being made of a flexible material. According to the present invention, the flow of the lavage fluid into other bronchi can be prevented, and the lavage fluid can be completely recovered in time after the lavage is completed.

Description

Lower respiratory tract lavage device
Technical Field
The invention relates to a lower respiratory tract lavage device for lavaging the bronchioloalveolar of a body cavity, in particular to a lower respiratory tract.
Background
At present, respiratory diseases have a straight-line rising trend due to atmospheric pollution and the like. It is well known in the art that diagnosis of bacterial etiology is of great importance for rational use of antibacterial agents and for improving prognosis, and that topical administration of the lower respiratory tract is also required to treat a certain disease.
Thus, there is a need to obtain lower respiratory lavage fluid for analysis or drug delivery to the lower respiratory tract. For example, a number of lavage devices have been developed in the prior art to lavage the respiratory tract to obtain lavage fluid for sampling the respiratory tract contaminating flora.
However, in the lavage device in the prior art, during the process of being sent to the lower respiratory tract, the bacteria group mixed in other parts in the lavage device cannot be strictly avoided, so that the sampling is inaccurate, and the collected sample is polluted and cannot accurately reflect the true pathogenic bacteria of the respiratory tract infection. In addition, since the lavage liquid needs to be extracted from the lavage site after the lavage is completed, the extracted lavage liquid cannot be prevented from remaining and contaminating other objects at the time of extraction.
Disclosure of Invention
It is an object of the present invention to provide a lower respiratory tract lavage device which can be used, for example, for lavage of the lower respiratory tract, in particular the bronchoalveoli of the lower respiratory tract, and which overcomes some or some of the drawbacks mentioned above.
The lower respiratory tract lavage device of the invention is used for lavaging the target part of the lower respiratory tract and collecting lavage liquid after lavage, and comprises:
a guide member having a generally cylindrical tube shape and having a proximal end adjacent to an operator and a distal end for extending into the lower respiratory tract, the guide member having an lavage fluid introduction portion on the proximal end for introducing lavage fluid into the guide member for guiding by the guide member to a target site to be lavaged;
a sealing member disposed near the distal end of the guide member for forming a seal between an outer wall of the guide member and an inner wall of a target site in the lower respiratory tract when the guide member is extended into the target site in the lower respiratory tract; and
an lavage liquid collection member disposed near the proximal end of the guide member for collecting lavage liquid after lavage,
wherein the guide member is made of a flexible material.
According to the invention, by forming a seal at the lavage site, the lavage fluid can be prevented from flowing into other bronchi, and can be completely recovered in time after the lavage is completed, so as not to cause secondary pollution.
Preferably, the guide member forms a chamfer, such as between 30 and 60 degrees, at the distal tube end to facilitate insertion of the guide member into the bronchi of the lower respiratory tract, such as a 40 degree chamfer.
According to one embodiment of the invention, the sealing member comprises a bladder provided on an outer wall of the guiding member and a fluid conduit located inside the guiding member, one end of the fluid conduit being in communication with the bladder and the other end being connected to a fluid supply means for filling the bladder with fluid, the bladder being made of a flexible material. The filled bladder is cylindrical in shape. According to this embodiment, the pouch filled with a fluid (such as a gas or liquid) can closely conform to the airway so that the airway can be supported and thus does not collapse upon back suction due to pressure changes.
According to one embodiment of the invention, the sealing member is an elastic protrusion provided on the guide member, the elastic protrusion being elastically deformable to form a seal between an outer wall of the guide member and an inner wall of the target site of the lower respiratory tract. Preferably, the elastic protrusion includes a holder provided on an outer wall of the guide member and a support provided inside the holder, wherein the holder is made of an elastic material and the support has elasticity. With this embodiment, the support is always able to place the holder in elastic contact with any part of the lower respiratory tract when the lower respiratory tract lavage device is placed in the lower respiratory tract of the user, thereby forming a good seal.
It will be clear to those skilled in the art that the resilient protrusion may also be of other construction, e.g. the resilient protrusion may be a unitary component and comprise a fixed end fixed to the guide member and a resiliently deformable end capable of being resiliently deformed in a radial direction to form a seal between the outer wall of the guide member and the inner wall of the lower respiratory tract.
According to another embodiment of the invention, the sealing member is an annular flange that fits over the outer diameter of the distal end of the guide member. Preferably, the annular flange is provided in a plurality (e.g., two, three or more) of which the diameters sequentially increase from the distal end toward the proximal end of the guide member. Preferably, each surface of the annular flange is an arc transition surface, so that the influence on the bronchus of a human body can be reduced.
According to an embodiment of the present invention, the lavage liquid collection member comprises a receiving container, a liquid receiving portion and a gas discharging portion, one end of the liquid receiving portion is connected to the proximal end of the guiding member and the other end thereof extends into the receiving container, and one end of the gas discharging portion extends into the receiving container and the other end thereof is connected to the negative pressure device, whereby a negative pressure can be formed in the receiving container. By the lavage liquid collecting member thus provided, lavage liquid can be sufficiently collected.
In a specific embodiment, the container has a dividing portion on the bottom, the dividing portion dividing the container into two parts, the liquid receiving portion and the gas discharging portion being located in the two parts, respectively, and a top of the dividing portion being higher than an end of the gas discharging portion in the container. By providing the dividing portion, the lavage fluid can be prevented from being sucked into the gas discharge portion.
In another specific embodiment, the diameter of the liquid receiving portion is smaller than the diameter of the gas discharging portion, and an end of the liquid receiving portion in the container is closer to the bottom of the container than an end of the gas discharging portion in the container is to the bottom of the container. By doing so, the pressure in the gas discharge portion can be made smaller than the pressure in the liquid receiving portion, thereby preventing the lavage liquid from being sucked backward.
Preferably, the container may be provided in a shape having a smaller upper part and a larger lower part, for example, a special shape, so that the container may be provided in a shape having a smaller upper part and a larger lower part, or in another special shape.
According to the invention, the problems that the lavage part is not required to be polluted or the lavage liquid flows back when the lavage liquid is pumped out due to the fact that the lavage can not be sealed or the sealing effect is poor in the prior art can be solved, the invention is suitable for the alveolar lavage of bronchi at any position in the lung, and in addition, the invention can be suitable for local administration of the lung to treat lung diseases.
Drawings
FIG. 1 is a general schematic of a lower airway lavage and lavage fluid collection member according to the present invention; and
fig. 2-4 are several embodiments of the catheter seal shown in fig. 1.
Detailed Description
The invention is further described below with reference to the accompanying drawings. It will be appreciated by those skilled in the art that the embodiments described below are merely illustrative of the present invention and are not intended to be limiting in any way. For example, while the invention has been described with respect to lavage of the lower respiratory tract, such as bronchoalveolar lavage, it will be apparent that it may be used in other suitable locations.
As shown in the embodiment of fig. 1, the lower respiratory tract lavage device of the present invention is for lavaging alveoli of bronchi of lower respiratory tract and can collect lavage liquid after lavage.
The lower respiratory tract lavage device comprises: a guide member 1, the guide member 1 being generally cylindrical in shape and having a proximal end 11 proximal to the operator and a distal end 12 for extending into the lower respiratory tract; an lavage fluid introduction portion 2 located on the proximal end of the guide member, the lavage fluid introduction portion 2 being for introducing lavage fluid into the guide member 1 for guiding by the guide member 1 into the bronchi to be lavaged; a sealing member 3 disposed near the distal end 12 of the guide member 1, the sealing member 3 for forming a seal between an outer wall of the guide member 1 and an inner wall of the bronchus when the guide member 1 is inserted into the bronchus in the lower respiratory tract; and an lavage fluid collection member 4 disposed proximate the proximal end 11 of the guide member 1, the lavage fluid collection member 4 for collecting lavage fluid after lavage.
The guide member 1 is made of a flexible material so as to be able to reduce the impact on the lower respiratory tract of the user when it is extended into the lower respiratory tract of the user.
The distal tube end of the guide member 1 may be beveled, such as between 30 and 60 degrees, to facilitate insertion of the guide member in the lower respiratory tract, for example preferably forming a 40 degree bevel.
Several embodiments of the sealing member 3 are described below with reference to fig. 2 to 4, respectively.
As shown in fig. 2, the sealing member 3 is formed as annular flanges 31 and 32 that fit over the outer diameter of the distal end 12 of the guide member 1. In addition, each face of the annular flange is a rounded transition face so as to minimize the effect on the bronchi when the guide member is extended into or removed from the bronchi.
Although two annular flanges are shown in fig. 2, the number of annular flanges is not limited, and for example, one or more annular flanges may be provided, and when two or more annular flanges are provided, the diameters of the annular flanges sequentially increase from the distal end 12 toward the proximal end 11 of the guide member 1, so that the annular flanges can be fitted over bronchi of different sizes on the lower respiratory tract, thereby increasing the suitability.
As shown in fig. 3, the sealing member 3 includes a balloon 33 provided on the outer wall of the guide member 1, and a fluid conduit 331 communicating with the balloon 33.
The bladder 33 is made of a flexible material. The other end of the fluid conduit 331 communicates with a fluid supply device, not shown, so that the bladder 33 may be filled with a fluid (e.g., a gas or a liquid), the filled bladder 33 having a cylindrical shape and allowing the outer wall of the bladder 33 to closely conform to the airway so that the airway may be supported and not collapse due to pressure changes upon aspiration.
As shown in fig. 4, the seal member 3 is an elastic projection provided on the guide member 1, and the elastic projection is elastically deformable so as to always form a seal between the outer wall of the guide member 1 and the inner wall of the target portion of the lower respiratory tract. Specifically, the elastic protrusion includes a holder 34 provided on the outer wall of the guide member 1 and a support 35 provided inside the holder 34, the holder 34 being made of an elastic material, and the support 35 having excellent elasticity, so that when the lower airway lavage device is placed into the bronchus of the lower airway of the user, the support 35 can always place the holder 34 in elastic contact with any portion of the bronchus of the lower airway, thereby forming a good seal.
The elastic protruding portion is not limited to the example shown in fig. 4, and for example, the elastic protruding portion may be a unitary member and include a fixed end fixed to the guide member 1 and an elastically deformed end capable of being elastically deformed in a radial direction to form a seal between an outer wall of the guide member 1 and an inner wall of the lower airway.
In addition, fig. 1 also shows an lavage liquid collection member 4, which lavage liquid collection member 4 comprises a receiving container 41, a liquid receiving portion 42 and a gas discharge portion 43.
Specifically, one end of the liquid receiving portion 42 is connected to the proximal end 11 of the guide member 1, and the other end thereof protrudes into the receiving container 41.
One end of the gas discharge portion 43 protrudes into the storage container 41, and the other end thereof is connected to a negative pressure forming device, not shown, to form a negative pressure in the storage container, so that lavage fluid can be sucked into the storage container 41 from the lower respiratory tract via the guide member.
As further shown in fig. 1, the diameter of the liquid receiving portion 42 is smaller than the diameter of the gas discharging portion 43, and the end of the gas discharging portion 43 in the storage container 41 is higher than the end of the liquid receiving portion 42 in the storage container 41. By thus providing the liquid receiving portion 42 and the gas discharge portion 43, the lavage liquid can be more reliably sucked into the receiving container 41.
Although not shown in fig. 1, the storage container 41 may have a dividing portion on the bottom thereof, the dividing portion being capable of dividing the storage container 41 into two portions in which the liquid receiving portion 42 and the gas discharging portion 43 are respectively located, and the top of the dividing portion needs to be higher than the end of the gas discharging portion 43 in the storage container 41, by thus providing the dividing portion, the lavage liquid can be prevented from being sucked back into the gas discharging portion 43 at the time of drawing out the lavage liquid.
The use and operation of the lower airway lavage device of the present invention will be briefly described below.
First, the guide member 1 is delivered to a bronchus to be treated in the lower respiratory tract through the oral cavity under the guidance of a bronchoscope, then the catheter sealing part 3 is made to form a seal between the guide member 1 and the bronchus of the lower respiratory tract, the lavage liquid is introduced into a site to be lavaged through the lavage liquid introducing part 2, after the lavage is completed, a negative pressure is formed in the storage container 41 by a negative pressure forming means (not shown) at the lavage liquid collecting member 4, so that the lavage liquid after the lavage is sucked from the lavage site into the storage container 41, and then the guide member 1 is taken out.

Claims (1)

1. A lower respiratory tract lavage device for lavaging a target site of a lower respiratory tract and collecting lavage fluid after lavage, comprising:
a guide member having a generally cylindrical tube shape and having a proximal end adjacent to an operator and a distal end for extending into the lower respiratory tract, the guide member having an lavage fluid introduction portion on the proximal end for introducing lavage fluid into the guide member for guiding by the guide member to a target site to be lavaged;
a sealing member disposed near the distal end of the guide member for forming a seal between an outer wall of the guide member and an inner wall of a target site in the lower respiratory tract when the guide member is extended into the target site in the lower respiratory tract; and
an lavage liquid collection member disposed near the proximal end of the guide member for collecting lavage liquid after lavage,
wherein the guide member is made of a flexible material, the guide member forming a chamfer of between 30 and 60 degrees at the distal tube end,
the sealing member is an elastic protrusion provided on an outer wall of the guide member, the elastic protrusion being elastically deformable to form a seal between the outer wall of the guide member and an inner wall of a target portion of the lower respiratory tract,
the elastic protrusion comprises a holder provided on an outer wall of the guide member and a support provided inside the holder, wherein the holder is made of an elastic material and the support has elasticity to be able to always place the holder in elastic contact with any portion of the bronchus of the lower respiratory tract to form a seal,
the lavage liquid collecting member comprises a receiving container, a liquid receiving portion and a gas discharging portion, wherein one end of the liquid receiving portion is connected with the proximal end of the guiding member, and the other end of the liquid receiving portion extends into the receiving container, and one end of the gas discharging portion extends into the receiving container, and the other end of the gas discharging portion is connected with the negative pressure device, so that negative pressure can be formed in the receiving container,
the diameter of the liquid receiving portion is smaller than the diameter of the gas discharging portion, and the end of the liquid receiving portion in the container is closer to the bottom of the container than the end of the gas discharging portion in the container is to the bottom of the container,
wherein the container has a dividing portion on the bottom, the dividing portion dividing the container into two portions, the liquid receiving portion and the gas discharging portion being located in the two portions, respectively, and a top of the dividing portion being higher than an end of the gas discharging portion in the container.
CN201710046062.XA 2017-01-22 2017-01-22 Lower respiratory tract lavage device Active CN106730102B (en)

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Application Number Priority Date Filing Date Title
CN201710046062.XA CN106730102B (en) 2017-01-22 2017-01-22 Lower respiratory tract lavage device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710046062.XA CN106730102B (en) 2017-01-22 2017-01-22 Lower respiratory tract lavage device

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CN106730102B true CN106730102B (en) 2024-02-06

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111298227B (en) * 2020-04-05 2021-09-07 山东第一医科大学第二附属医院 Pulmonary alveolus lavage device for pneumonia

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246012A (en) * 1990-12-21 1993-09-21 Ballard Medical Products Bronchoalveolar lavage catheter
CN2197073Y (en) * 1994-02-23 1995-05-17 王伟 A transporting-tube device of bronchus
CN201263806Y (en) * 2008-08-15 2009-07-01 王连兴 Bronchial alveolar lavation liquid and stomach juice collector
CN201441391U (en) * 2009-06-08 2010-04-28 鲁德玕 Anti-pollution device for collecting irrigating solution of pulmonary alveolus
CN102119038A (en) * 2008-06-09 2011-07-06 护理联合2200公司 Diagnostic sample collection system
CN204501827U (en) * 2015-03-20 2015-07-29 南京市胸科医院 The multi-functional gathering-device of Whole lung lavage drainage-fluid

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246012A (en) * 1990-12-21 1993-09-21 Ballard Medical Products Bronchoalveolar lavage catheter
CN2197073Y (en) * 1994-02-23 1995-05-17 王伟 A transporting-tube device of bronchus
CN102119038A (en) * 2008-06-09 2011-07-06 护理联合2200公司 Diagnostic sample collection system
CN201263806Y (en) * 2008-08-15 2009-07-01 王连兴 Bronchial alveolar lavation liquid and stomach juice collector
CN201441391U (en) * 2009-06-08 2010-04-28 鲁德玕 Anti-pollution device for collecting irrigating solution of pulmonary alveolus
CN204501827U (en) * 2015-03-20 2015-07-29 南京市胸科医院 The multi-functional gathering-device of Whole lung lavage drainage-fluid

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