CN106729388A - It is a kind of to treat Chinese medicine preparation of hyperlipidemia and preparation method thereof - Google Patents

It is a kind of to treat Chinese medicine preparation of hyperlipidemia and preparation method thereof Download PDF

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CN106729388A
CN106729388A CN201611167389.4A CN201611167389A CN106729388A CN 106729388 A CN106729388 A CN 106729388A CN 201611167389 A CN201611167389 A CN 201611167389A CN 106729388 A CN106729388 A CN 106729388A
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chinese medicine
medicine preparation
hyperlipidemia
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汪杰峰
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
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    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

By weight it is to include following traditional Chinese medicine ingredients the invention discloses a kind of Chinese medicine preparation for treating hyperlipidemia:Dried orange peel 13g, tuber of pinellia 13g, Radix Glycyrrhizae 3g, rhizoma alismatis 13g, coix seed 28g, oriental wormwood 18g, Snakegourd Fruit 16g, charred FRUCTUS CRATAEGI 13g, lotus leaf 13g, root tuber of aromatic turmeric 13g.The preparation and application of Chinese medicine composition of the present invention:It is decocted in water for oral dose:It is daily 1 clothes, 7 doses be a course for the treatment of, it is necessary to the course for the treatment of of medication 26.

Description

It is a kind of to treat Chinese medicine preparation of hyperlipidemia and preparation method thereof
Technical field
It is to be related to a kind of Chinese medicine preparation for treating hyperlipidemia specifically the invention belongs to Chinese medicine composition.
Background technology
Hyperlipidemia urine disease is a kind of because fat metabolism or operating exception make one or more lipid of blood plasma higher than normal Referred to as hyperlipidemia, lipid is insoluble or poorly soluble in water and must be combined with protein to be existed with lipoprotein form, therefore, hyperlipidemia Often it is hyperlipoprotememia, shows as hypercholesterolemia, hypertriglyceridemia or both and have concurrently, is clinically divided into two classes: 1. primary, rare, belongs to heredity disorders of lipid metabolism disease;2. Secondary cases, is common in the bad diabetes of control, drinks, first shape Adenasthenia disease, nephrotic syndrome, Rend dialysis, kidney transplant, biliary obstruction, oral contraceptive etc..Primary person sees children, Secondary cases person is more in 20 years old sequela, and majority are asymptomatic to be found only when physical examination, coronary heart disease also can in one's early years occur and other are dynamic Pulse atherosclerosis disease such as apoplexy, peripheral angiopathy is often accompanied by obesity, impaired glucose tolerance(Or diabetes), pancreas islet high Plain mass formed by blood stasis, hyperuricemia can occur acute pancreatitis, often occur xanthelasma be located at it is upper, palpebra inferior or xanthoma tendinosum are stretched in limbs Pleural muscle tendon, such as olecranon, kneecap, heel portion have pain and tenderness during with myotenositis.It is generally often liver kidney yin that this sick pathogenesis is long Void, the turbid congestion blood block of phlegm.
The present invention is become silted up by phlegm and started with, and is invigorated blood circulation with stagnation resolvation and made laws, and is treated with card change, achieves good therapeutic effect, long-term clothes Hyperlipidemia can be cured after.
The content of the invention
Present invention aim to address the problem in prior art, spy provide a kind of effect substantially, the course for the treatment of is shorter controls Treat the Chinese medicine preparation of hyperlipidemia.
In order to realize foregoing invention purpose, the present invention is made the raw material composition and its weight proportion of the effective ingredient For:Dried orange peel 13g, tuber of pinellia 13g, Radix Glycyrrhizae 3g, rhizoma alismatis 13g, coix seed 28g, oriental wormwood 18g, Snakegourd Fruit 16g, charred FRUCTUS CRATAEGI 13g, lotus leaf 13g, root tuber of aromatic turmeric 13g.
The preparation and application of Chinese medicine composition of the present invention:It is decocted in water for oral dose:It is daily 1 clothes, 7 doses be a course for the treatment of, it is necessary to medication The 2-6 courses for the treatment of.
The Chinese medicine preparation for treating hyperlipidemia is invented, natural drug is selected, for the hyperlipidemia cause of disease interpretation of the cause, onset and process of an illness, each taste Medicinal material respectively has its effect, coordinates mutually, the tuber of pinellia, dried orange peel dampness removing resolving sputum in side;Dried orange peel promoting the circulation of qi resolving sputum;Poria cocos, coix seed dampness elimination are good for Spleen;Rhizoma alismatis eliminating dampness and diuresis;Lotus leaf is removed dampness by means of aromatics;Oriental wormwood clearing damp cholagogic;Root tuber of aromatic turmeric blood-activating and qi-promoting, solves strongly fragrant cholagogic.Above-mentioned all herbal medicines Share, mutually collaboration bring out the best in each other, play altogether clearing heat and detoxicating, clearing heat and promoting diuresis, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, Huoxue San " The stasis of blood, dissipating bind dredging collateral, the effect of mass dissipating and swelling eliminating, all medicines share, phlegm reduction of blood circulation promoting, function of invigorating circulation and reducing blood fat, to treat the good recipe of hyperlipidemia.
Specific embodiment
Embodiment 1:A kind of Chinese medicine preparation for treating hyperlipidemia, by weight including following traditional Chinese medicine ingredients:Dried orange peel 13g, tuber of pinellia 13g, Radix Glycyrrhizae 3g, rhizoma alismatis 13g, coix seed 28g, oriental wormwood 18g, Snakegourd Fruit 16g, charred FRUCTUS CRATAEGI 13g, lotus leaf 13g, root tuber of aromatic turmeric 13g。
Embodiment 2:If patient has insufficiency of the spleen symptom, ginseng 16g, Radix Codonopsis 12g, bighead atractylodes rhizome 10g, the Radix Astragali are added in said components 20g。
Embodiment 3:If patient has deficiency of the kidney, tuber of multiflower knotweed 12g, sealwort 15g, Radix Angelicae Sinensis 16g, the bark of eucommia are added in said components 16g。
Embodiment 4:If patient has stagnation of liver qi symptom, cassia seed 20g, yncaria stem with hooks 15g are added in said components.
Embodiment 5:The blood stasis symptom if patient has good manners, the attached 16g of perfuming in said components, dried orange peel 20g, red sage root 15g, Radix paeoniae rubrathe 16g, peach kernel 20g.
It is decocted in water for oral dose:It is daily 1 clothes, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
The clinical treatment effect of the Chinese medicine preparation for hyperlipidemia nursing of the present invention is illustrated below by way of practical example Really.
1st, clinical data
50 hyperlipidemia patients, are more than 1 year hyperlipidemia medical history, patient's average age 45 ± 20 years old (25~65 years old), Meet "《Chinese medical disease Standardization of diagnosis and curative effect》Hyperlipidemia diagnostic criteria in (State Administration of Traditional Chinese Medicine's promulgation) ", all examines It is hyperlipidemia patient to break.
The symptoms such as 50 hyperlipidemia patients are all had a dizzy spell, have a headache, limb fiber crops
2nd, criterion of therapeutical effect
Cure:Clinical symptom disappearance, indices are normal;
It is effective:Clinical symptoms substantially mitigate, and part index number is normal;
It is invalid:Clinical symptoms are without substantially mitigation, exacerbation of symptoms, and it is invalid to be judged to.
3rd, treatment results
After 50 hyperlipidemia patients treat 3~4 courses for the treatment of, cure 38, treat effective 8, invalid 2.Treatment total effective rate It is 93%.
Typical case:
Shen, male 54 years old, sample pain is squeezed 5 hours after breastbone.Past medical history:Multiple lacunar infarction, chronic kidney is not Entirely, fatty liver, liver multiple cyst, thyroid nodule, cholecystolithiasis, Peripheral atherosclerosis, hyperlipemia.Allergies:It is blue or green Mycin, trauma history:Right Lower Abdomen is injured.History of operation:Appendectomy, right hernia resection, prostatectomy in 2000.1.3 Training situation(Physical examination):T:36.5 DEG C, P:76 beats/min, R:16 beats/min, BP:160/80mmHg.Sanity, cooperation of having a medical check-up, Face, skin sclera have no xanthochromia, and superficial lymph knot does not touch enlargement, and 76 beats/min of heart rate, the rhythm of the heart is neat, and heart sound is normal, do not hear and Noise.Double lungs are not heard and rale, and abdomen is soft, and without tenderness, liver spleen is not touched.Double lower limb is without oedema.Physiological reflex is present, pathologic reflex Do not draw.Have a medical check-up:Have the fidgets, double pulmonary respiration sounds are clear, 105 beats/min of heart rate, rule is neat, and heart sound is low.Previously intentionally angina medical history. Prepare received treatment of Chinese herbs, after take 6 doses of inventive formulation, be decocted in water for oral dose, daily 1 dose, it is daily 1 clothes.Second examines:Pain is slightly felt and being subtracted Gently, 12 doses of following the service, three examine:Pain elementary solution is removed, and is after treatment effect afterwards, is advised and is continued to take 12 doses.Follow-up 1 year, all Normally.

Claims (5)

1. a kind of Chinese medicine preparation for treating hyperlipidemia, it is characterised in that:The Chinese medicine preparation includes following Chinese medicine by weight Composition:Dried orange peel 13g, tuber of pinellia 13g, Radix Glycyrrhizae 3g, rhizoma alismatis 13g, coix seed 28g, oriental wormwood 18g, Snakegourd Fruit 16g, charred FRUCTUS CRATAEGI 13g, lotus leaf 13g, root tuber of aromatic turmeric 13g.
2. the Chinese medicine preparation of hyperlipidemia is treated as claimed in claim 1, it is characterised in that:The Chinese medicine preparation also includes ginseng 16g, Radix Codonopsis 12g, bighead atractylodes rhizome 10g, Radix Astragali 20g.
3. the Chinese medicine preparation of hyperlipidemia is treated as claimed in claim 1, it is characterised in that:The Chinese medicine preparation also includes that what is first Black 12g, sealwort 15g, Radix Angelicae Sinensis 16g, bark of eucommia 16g.
4. the Chinese medicine preparation of hyperlipidemia is treated as claimed in claim 1, it is characterised in that:The Chinese medicine preparation also includes Cassia Sub- 20g, yncaria stem with hooks 15g.
5. the Chinese medicine preparation of hyperlipidemia is treated as claimed in claim 1, it is characterised in that:The Chinese medicine preparation also includes rhizoma cyperi 16g, dried orange peel 20g, red sage root 15g, radix paeoniae rubrathe 16g, peach kernel 20g.
CN201611167389.4A 2016-12-16 2016-12-16 It is a kind of to treat Chinese medicine preparation of hyperlipidemia and preparation method thereof Withdrawn CN106729388A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108404062A (en) * 2018-06-11 2018-08-17 北京中医药大学 Treat the Chinese medicine composition and its preparation method and application of hyperlipidemia
CN109925469A (en) * 2017-12-18 2019-06-25 上海市中医医院 A kind of Chinese medicine composition that treating liver-depression and spleen-insufficiency type nonalcoholic fatty liver and application
CN112913947A (en) * 2021-04-15 2021-06-08 王晓军 Gynostemma pentaphylla lipid-lowering tea

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109925469A (en) * 2017-12-18 2019-06-25 上海市中医医院 A kind of Chinese medicine composition that treating liver-depression and spleen-insufficiency type nonalcoholic fatty liver and application
CN109925469B (en) * 2017-12-18 2021-07-30 上海市中医医院 Traditional Chinese medicine composition for treating liver-stagnation and spleen-deficiency type non-alcoholic fatty liver disease and application thereof
CN108404062A (en) * 2018-06-11 2018-08-17 北京中医药大学 Treat the Chinese medicine composition and its preparation method and application of hyperlipidemia
CN108404062B (en) * 2018-06-11 2021-02-05 北京中医药大学 Traditional Chinese medicine composition for treating hyperlipidemia and preparation method and application thereof
CN112913947A (en) * 2021-04-15 2021-06-08 王晓军 Gynostemma pentaphylla lipid-lowering tea

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