CN106728993A - A kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge and its production method - Google Patents

A kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge and its production method Download PDF

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Publication number
CN106728993A
CN106728993A CN201510820296.6A CN201510820296A CN106728993A CN 106728993 A CN106728993 A CN 106728993A CN 201510820296 A CN201510820296 A CN 201510820296A CN 106728993 A CN106728993 A CN 106728993A
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parts
root
tranquilization
lozenge
nourishing blood
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戴路
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Harbin Moyi Biotechnology Co Ltd
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Harbin Moyi Biotechnology Co Ltd
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962Allium, e.g. garden onion, leek, garlic or chives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

A kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge and its production method.By willowleaf spiraea herb and root, peach kernel, Longstamen Onion Bulb, corn stigma, the bark of official magnolia, fructus cannabis, Exocarpium Citri Grandis, the seed of cowherb, carboxymethylcellulose calcium, Water soluble starch, Glucose Constituted Deng raw material, finished product is made by sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging. Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept;By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.The present invention Have Health care, nourishing blood and tranquilization, pure natural, pollution-free, no side effectses, the advantages of conveniently take and nourish the body.

Description

A kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge and its production method
Technical field:
The present invention relates to field of food health care, and in particular to a kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge and its production method.
Background technology
Buccal tablet refers to the compressed tablets for being contained in slow mechanism dissolved in oral cavity, and lozenge will have tempting color from inside to outside, so that the mouthfeel that user has had.Therefore, the figuration composition in lozenge, such as sugar, pigment additive often " a presumptuous guest usurps the role of the host " so that some by mistake lozenge is regarded as " sugar ".
At present, most of lozenge of in the market is all medicine, and most of medicines for being to treat Throat diseases, and narrow application range, therapeutic effect is general.And it is few using the utilization rate for being processed into health products containing chip technology, it is few to body-care effect, it is impossible to meet the market demand.
The content of the invention:
It is an object of the invention to provide one kind collection nourishing blood and tranquilization, it is pure natural, pollution-free, No side effectses are conveniently taken and are nourished the body in one Willowleaf spiraea herb and root nourishing blood and tranquilization lozenge and production method.
The object of the present invention is achieved like this.It is that the raw material matched somebody with somebody by following weight is made, Willowleaf spiraea herb and root 15-30 Part, peach kernel 10-20 Part, Longstamen Onion Bulb 5-15 Part, corn stigma 3-15 Part, the bark of official magnolia 3-15 Part, fructus cannabis 3-10 Part, Exocarpium Citri Grandis 4-12 Part, the seed of cowherb 6-9 Part, carboxymethylcellulose calcium 7-10 Part, water soluble starch 4-8 Part, glucose 10-15 Part.
Preparing willowleaf spiraea herb and root nourishing blood and tranquilization lozenge preferred weight ratio range of the present invention is, Willowleaf spiraea herb and root 15-25 Part, peach kernel 10-15 Part, Longstamen Onion Bulb 5-12 Part, corn stigma 3-10 Part, the bark of official magnolia 3-10 Part, fructus cannabis 3-8 Part, Exocarpium Citri Grandis 4-10 Part, the seed of cowherb 6-8 Part, carboxymethylcellulose calcium 7-9 Part, water soluble starch 4-7 Part, glucose 10-14 Part.
Preparing willowleaf spiraea herb and root nourishing blood and tranquilization lozenge best weight ratio scope of the present invention is, Willowleaf spiraea herb and root 20 Part, peach kernel 12 Part, Longstamen Onion Bulb 10 Part, corn stigma 8 Part, the bark of official magnolia 8 Part, fructus cannabis 5 Part, Exocarpium Citri Grandis 8 Part, the seed of cowherb 7 Part, carboxymethylcellulose calcium 8 Part, water soluble starch 6 Part, glucose 12 Part.
Above-mentioned each component is made the production method of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge of the present invention, technical process is:Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively:
A , sorting, by raw material weight proportioning of soup processed, select meet the willowleaf spiraea herb and root of national health and quality standard, peach kernel, Longstamen Onion Bulb, corn stigma, the bark of official magnolia, fructus cannabis, Exocarpium Citri Grandis, the seed of cowherb, carboxymethylcellulose calcium, Water soluble starch, Glucose feed is standby;
B , drying, except carboxymethylcellulose calcium, Water soluble starch, Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists 80-100 DEG C, the time 45 Minute, raw material moisture is evaporated to water content 18% , compressing tablet;
C , decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device 2 It is secondary, add for the first time 7 Times water is decocted 1.5 Hour, second frame 5 Times water is decocted 1 Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution;
D , mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor;
E , powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby;
F , compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet;Tablet press machine direct tablet compressing is utilized after compressing tablet;
G , packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
With lozenge be combined the traditional Chinese medicine ingredients for having good tonic effect to human body by the present invention, there is more preferable assimilation effect compared to existing lozenge, it is convenient for people to usually take, conditioning health, increase metabolism balance in vivo, regulation human body homeostasis is softer, and lifting constitution is gentler, effective for a long time can increase human body power and work endurance.
Active ingredient in Chinese medicine is decocted and is made extract solution by the present invention, active ingredient is combined with lozenge, the nutriment in the Chinese medicine being effectively kept;By the proportioning of science, when product of the present invention is nourished human body, with mending without dry, trophic structure rationally, strengthens effect of human body constitution.
In inventive formulation, willowleaf spiraea herb and root nourishing blood and tranquilization, sharp water defaecation, nourishing blood and tranquilization, main traumatic injury, joint pain, amenorrhoea, dysmenorrhoea, difficult urination, constipation, coughing with a lot of sputum;Peach kernel promoting blood circulation, relaxes bowel;For Amenorrhea, dysmenorrhoea , wei lump in the abdomen lump in the abdomens, injury from falling down, dry constipation of intestines; Longstamen Onion Bulb activates yang and remove abstruction, and promoting the circulation of qi is led stagnant;For obstruction of qi in the chest pain, phlegm and retained fluid cough and asthma lets out weight after dysentery;Corn stigma is mild-natured, slightly sweet flavor, nontoxic;Enter liver, kidney, bladder warp.Diuresis, expels the heat-evil, soothing the liver, cholagogic.Control nephritic dropsy, tinea pedis, icterohepatitis, hypertension, cholecystitis, gall stone, diabetes, hematemesis and epistaxis, nasosinusitis, acute mastitis;Bark of official magnolia eliminating dampness dissolving phlegm, lower gas removes full;For in humidity hysteresis wound, gastral cavity ruffian is vomited and diarrhoea, stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm and retained fluid is breathed with cough;Fructus cannabis is clearing heat and detoxicating, cool blood relieving sore-throat;For febrile virulent maculae, tongue is dark reddish purple dark, mumps, larynx numbness, scarlet fever, major part pestilence, erysipelas, carbuncle swells;Exocarpium Citri Grandis resolving sputum, qi-regulating, stomach invigorating helps digestion;Control phlegm in the heart stagnant, cough and asthma vomits hiccup, eating accumulation; Seed of cowherb invigorate blood circulation, lower breast detumescence;For agalactia, Amenorrhea, dysmenorrhoea, acute mastitis swells and ache
The present invention is summarized and perfect in taking and clinical verification by many cases patient, constantly, and recipe ratio is more complete, determined curative effect, to traumatic injury, joint pain Deng master Disease Card:Degree difference is served Nourishing blood and tranquilization, sharp water defaecation Effect, Have The advantages of health care, nourishing blood and tranquilization, pure natural, pollution-free, no side effectses.
The present invention through two groups of clinical verifications, for treatment group take lozenge of the present invention, take once a day by one of which, and 7 days is a course for the treatment of, and " Anshen Bunao mixture " is taken in another group of control, Take once a day, be within 7 days a course for the treatment of, every group selection outpatient 200, wherein man 100, female 100, measure the big age 77 It is year, minimum Age 22 Year, Clinical manifestation is traumatic injury, joint pain, difficult urination, constipation, coughing with a lot of sputum , obstruction of qi in the chest pain, phlegm and retained fluid cough and asthma lets out weight after dysentery , Nephritic dropsy, tinea pedis , table one is to take the contrasting data after a course for the treatment of:
Table 1 Front and rear two groups of courses for the treatment of are taken to compare ( Unit : People )
There were significant differences for treatment group and control group, it will thus be seen that present invention application clinically has significant curative effect.
Technological advantage of the invention is:1st, raw material and scientific formulation are selected, production technology is advanced, its product produces taste well, convenient storage;2nd, without harmful components such as preservatives in product, nourishing and nutrition of the raw material to human body are kept, is easily absorbed by the body;3rd, raw material sources are extensive, plus process line is short, the manufacture of product easy processing.
Specific embodiment
With reference to specific embodiment, the present invention is further illustrated
Embodiment 1:Suitable for traumatic injury, joint pain, difficult urination Crowd
Willowleaf spiraea herb and root nourishing blood and tranquilization lozenge of the present invention is prepared to be made up of following component raw material(Consumption is weight portion), Willowleaf spiraea herb and root 15-30 Part, peach kernel 10-20 Part, Longstamen Onion Bulb 5-15 Part, corn stigma 3-15 Part, the bark of official magnolia 3-15 Part, fructus cannabis 3-10 Part, Exocarpium Citri Grandis 4-12 Part, the seed of cowherb 6-9 Part, carboxymethylcellulose calcium 7-10 Part, water soluble starch 4-8 Part, glucose 10-15 Part.
Embodiment 2:Suitable for constipation, coughing with a lot of sputum , obstruction of qi in the chest pain, phlegm and retained fluid cough and asthma Crowd
Preparing willowleaf spiraea herb and root nourishing blood and tranquilization lozenge preferred weight ratio range of the present invention is: Willowleaf spiraea herb and root 15-25 Part, peach kernel 10-15 Part, Longstamen Onion Bulb 5-12 Part, corn stigma 3-10 Part, the bark of official magnolia 3-10 Part, fructus cannabis 3-8 Part, Exocarpium Citri Grandis 4-10 Part, the seed of cowherb 6-8 Part, carboxymethylcellulose calcium 7-9 Part, water soluble starch 4-7 Part, glucose 10-14 Part.
Embodiment 3 :It is applied to Let out weight after dysentery , Nephritic dropsy, tinea pedis Crowd
Preparing willowleaf spiraea herb and root nourishing blood and tranquilization lozenge best weight ratio scope of the present invention is, 20 parts of willowleaf spiraea herb and root, 12 parts of peach kernel, 10 parts of Longstamen Onion Bulb, 8 parts of corn stigma, 8 parts of the bark of official magnolia, 5 parts of fructus cannabis, 8 parts of Exocarpium Citri Grandis, 7 parts of the seed of cowherb, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
Embodiment 4
Above-mentioned each component is made the production method of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge of the present invention, technical process is:Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively:
A , sorting, by raw material weight proportioning of soup processed, select meet the willowleaf spiraea herb and root of national health and quality standard, peach kernel, Longstamen Onion Bulb, corn stigma, the bark of official magnolia, fructus cannabis, Exocarpium Citri Grandis, the seed of cowherb, carboxymethylcellulose calcium, Water soluble starch, Glucose feed is standby;
B , drying, except carboxymethylcellulose calcium, Water soluble starch, Outside glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control exists 80-100 DEG C, the time 45 Minute, raw material moisture is evaporated to water content 18% , compressing tablet;
C , decoct, by above-mentioned ratio of weight and number, decocted during the raw material addition after drying is put into decocting device 2 It is secondary, add for the first time 7 Times water is decocted 1.5 Hour, second frame 5 Times water is decocted 1 Hour, filtrate is extracted in filtering respectively, will filtrate merging twice, the secondary filter dregs of a decoction and impurity, prepared extract solution;
D , mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor;
E , powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby;
F , compressing tablet, by above-mentioned mixed powder remove production process in generation impurity, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet;Tablet press machine direct tablet compressing is utilized after compressing tablet;
G , packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
Embodiment 2
If adding appropriate disintegrant such as in the prescription of lozenge CMS-Na Improve and contain tablet stability, or add the mediation mouthfeel such as cane sugar powder, mannitol, sorbierite, various sweeteners, essence.

Claims (4)

1. a kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge, it is characterised in that:It is that the raw material matched by following weight is made, willowleaf spiraea herb and root 15-30 parts, peach kernel 10-20 parts, Longstamen Onion Bulb 5-15 parts, corn stigma 3-15 parts, bark of official magnolia 3-15 parts, fructus cannabis 3-10 parts, Exocarpium Citri Grandis 4-12 parts, seed of cowherb 6-9 parts, carboxymethylcellulose calcium 7-10 parts, water soluble starch 4-8 parts, glucose 10-15 parts.
2. a kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge according to claim 1, it is characterised in that:The weight proportion of wherein various raw materials is, willowleaf spiraea herb and root 15-25 parts, peach kernel 10-15 parts, Longstamen Onion Bulb 5-12 parts, corn stigma 3-10 parts, bark of official magnolia 3-10 parts, fructus cannabis 3-8 parts, Exocarpium Citri Grandis 4-10 parts, seed of cowherb 6-8 parts, carboxymethylcellulose calcium 7-9 parts, water soluble starch 4-7 parts, glucose 10-14 parts.
3. a kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge according to claim 1, it is characterised in that:The weight proportion of wherein various raw materials is, 20 parts of willowleaf spiraea herb and root, 12 parts of peach kernel, 10 parts of Longstamen Onion Bulb, 8 parts of corn stigma, 8 parts of the bark of official magnolia, 5 parts of fructus cannabis, 8 parts of Exocarpium Citri Grandis, 7 parts of the seed of cowherb, 8 parts of carboxymethylcellulose calcium, 6 parts of water soluble starch, 12 parts of glucose.
4. the production method of the willowleaf spiraea herb and root nourishing blood and tranquilization lozenge according to claim 1-3, it is characterised in that:Technical process is:Sorting, drying, decoction, mixing, powder processed, compressing tablet, packaging, concrete operation method follow these steps to successively:
A, sorting, by raw material weight proportioning of soup processed, select that to meet the willowleaf spiraea herb and root of national health and quality standard, peach kernel, Longstamen Onion Bulb, corn stigma, the bark of official magnolia, fructus cannabis, Exocarpium Citri Grandis, the seed of cowherb, carboxymethylcellulose calcium, water soluble starch, glucose feed standby;
B, drying, in addition to carboxymethylcellulose calcium, water soluble starch, glucose, other raw materials are cut into block or sheet and are placed in desiccation in drying baker respectively, and temperature control 45 minutes time, makes raw material moisture be evaporated to water content 18%, compressing tablet at 80-100 DEG C;
C, decoction, by above-mentioned ratio of weight and number, decocted 2 times during the raw material addition after drying is put into decocting device, for the first time plus 7 times of waters are decocted 1.5 hours, second frame, 5 times of waters are decocted 1 hour, and filtrate is extracted in filtering respectively, filtrate will be merged twice, the secondary filter dregs of a decoction and impurity, are obtained extract solution;
D, mixing, by above-mentioned ratio of weight and number, carboxymethylcellulose calcium, water soluble starch, glucose will be added to be sufficiently mixed uniformly in extract solution, prepared mixed liquor;
E, powder processed, the filtrate of above-mentioned mixed liquor is cooled to room temperature, filtrate is made mixed powder using spray drying process, it is standby;
F, compressing tablet, the impurity that above-mentioned mixed powder is removed the generation in production process, then using the mode and ultraviolet compressing tablet mode compressing tablet for radiating compressing tablet;Tablet press machine direct tablet compressing is utilized after compressing tablet;
G, packaging, by the good tablet of above-mentioned pressing according to specification for sale pack.
CN201510820296.6A 2015-11-24 2015-11-24 A kind of willowleaf spiraea herb and root nourishing blood and tranquilization lozenge and its production method Pending CN106728993A (en)

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