CN106728099A - It is a kind of to treat medicine of rheumatic arthritis and preparation method thereof - Google Patents
It is a kind of to treat medicine of rheumatic arthritis and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
Abstract
Medicine of rheumatic arthritis and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by Radix Angelicae Sinensis, the root of Dahurain angelica, levisticum, radix aconiti sinensis, RADIX ACONITI KUSNEZIFFII, pawpaw, medicine of the present invention has eliminating stasis to subdue swelling, active analgesic therapy, dispelling wind and eliminating dampness, the function of promoting blood circulation for regulating menstruation, for treating rheumatic arthritis instant effect, good effect, has no side effect.
Description
Technical field
The present invention relates to a kind of medicine for treating rheumatic arthritis, belong to the field of Chinese medicines.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT, belong to allergic disease, more with
Febris acuta and arthralgia onset, typical performance is the heating of slight or moderate, and affected joints are generally knee, ankle, shoulder, elbow, wrist etc.
Large joint, common to be transferred to another joint by a joint, lesion is locally presented red, swollen, scorching hot, severe pain, some patients
There are several joints to fall ill simultaneously, recurrent exerbation and heart can be involved, then myocarditis can occur, or even leave valve disorder.
Because current Western medicine cannot fast and effectively treat rheumatic arthritis.Therefore, Chinese medicine of the people to treatment rheumatic arthritis
There is great demand in medicine, up to now, it has not been found that on relevant report of the invention.
The content of the invention
The present inventor have found effectively treatment rheumatism finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science
The arthritic medicine of property, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment rheumatic arthritis.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is selection Radix Angelicae Sinensis, the root of Dahurain angelica, levisticum, radix aconiti sinensis, RADIX ACONITI KUSNEZIFFII, pawpaw, the root of bidentate achyranthes, the bark of eucommia, Radix Glycyrrhizae, breast
Perfume, myrrh, earthworm bulk drug are combined preparation, and these drug regimens are caused into each efficacy of drugs produces synergy, from
And can effectively treat rheumatic arthritis.Wherein there is benefit because its nature and flavor sweet, acrid, warm, enters the heart, liver, the spleen channel from Radix Angelicae Sinensis
Blood is invigorated blood circulation, menstruction regulating and pain relieving, the function of moisturize laxation, controls irregular menstruation, and Amenorrhea stomachache , Disorder lumps in the abdomen knot gathers, and uterine bleeding, headache due to deficiency of blood is dizzy
Dizzy, Impotence numbness, intestinal dryness is difficult just, weight, ulcer sores, metal-inflicted wound, injury from falling down after dysentery characterized by blood in the stool.From the root of Dahurain angelica because its nature and flavor is pungent, temperature enters
Lung, spleen, stomach, there is wind-dispelling, and eliminating dampness, detumescence, the function of analgesic controls headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, cold-dampness stomachache, intestines
Wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin is dry itches, mange.From levisticum because its nature and flavor is arduous, temperature enters kidney, bladder
Through, there is wind-dispelling, win wet, cold dispelling, the function of analgesic controls wind-cold-dampness arthralgia, and waist urushic acid bitterly, bitterly, have a headache trick contraction by chronic bronchitis,
Dentalgia.From radix aconiti sinensis because its nature and flavor is pungent, heat is poisonous, enters spleen, the warp of the gate of vitality two, there is dispellieg cold and dampness, dissipates ailment said due to cold or exposure, Wen Jing, analgesic
Function, control wind-cold-dampness arthralgia, severe and wadering arthralgia bitterly, spasm of limbs, hemiplegia, head wind headache, trusted subordinate's crymodynia, cloudy subcutaneous ulcer pyogenic infections.From
RADIX ACONITI KUSNEZIFFII, different name radix aconiti agrestis, its nature and flavor are pungent, and heat, poisonous, enter liver, spleen, lung channel search wind prevailing over dampness, and eliminating cold to stop pain opens phlegm, detumescence
Function, controls wind-cold-dampness arthralgia, paralysis due to windstroke, lockjaw, head wind, coldness and pain in the epigastrium, phlegm addiction, air parcel, cold dysentery, larynx numbness, ulcer, furunculosis,
Scrofula.From pawpaw because its nature and flavor is sour, temperature, enter liver, the spleen channel have suppressing the hyperactive liver and easing the stomach, the function of the relaxing muscles and tendons that dries, and control vomiting and diarrhoea and turn
Muscle, arthritis with fixed pain caused by dampness, tinea pedis, oedema, dysentery.From the root of bidentate achyranthes because its nature and flavor sweetness and bitterness is sour, put down, enter liver and kidney channel, life scattered blood stasis disappear
The function of carbuncle swells, controls gonorrhoea, and hematuria, Amenorrhea , Disorder lumps in the abdomen, difficult labour, placenta retension, postpartum blood stasis stomachache, larynx numbness, carbuncle swells, bruise is damaged
Control waist and knee ostalgia, spasm of limbs, Impotence numbness are controlled in wound, ripe use filling liver kidney, strengthening the bones and muscles.From the bark of eucommia because the sweet micro-pungent of its nature and flavor, warm,
Enter liver and kidney channel, there is filling liver kidney, strengthening the bones and muscles, antiabortive function controls spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination, tire
Leakage is intended to fall, hypertension.From Radix Glycyrrhizae because its property sweet taste, enters spleen, stomach, lung channel, have and reconciled with middle emergency, moistening lung, removing toxic substances
The function of all medicines, processs, deficiency of food weakness of the spleen and the stomach with controlling, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, palpitaition, shies carbuncle, raw with controlling pharynx
Larynx swells and ache, peptic ulcer, ulcer sores, and antidote is malicious and poisons by food.From frankincense because its nature and flavor is arduous, temperature, enter the heart,
Liver, the spleen channel, there is regulating qi and activating blood, and analgesic therapy, the function of chasing after poison controls qi and blood stagnation, trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, pain
Through postpartum blood stasis stabbing pain.From myrrh because its is bitter in taste, put down, enter Liver Channel, there are scattered blood stasis eliminatings, the function of detumescence ding-tong is controlled
Fall damage, metal-inflicted wound, muscles and bones, all Tong , Disorder lumps in the abdomen of trusted subordinate, Amenorrhea, ulcer sore pain, anal fistula, mesh barrier.From earthworm because its nature and flavor is salty,
Cold, enter liver, spleen, lung channel have a heat-clearing, soothing the liver, Zhichuan, the function of dredging collateral, and it is manic to control hyperpyrexia, convulsion, headache due to pathogenic wind-heat, mesh
Red, apoplexy and hemiplegia is panted, larynx numbness, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, sore.
Specific embodiment
The drug dose of present invention combination is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy
All there is good therapeutic effect in the range of amount
12-20 grams of Radix Angelicae Sinensis 10-15 grams of levisticum of 10-15 grams of the root of Dahurain angelica
5-12 grams of radix aconiti sinensis 5-12 grams of pawpaw of 5-12 grams of RADIX ACONITI KUSNEZIFFII
12-20 grams of root of bidentate achyranthes 5-12 grams of Radix Glycyrrhizae of 12-20 grams of the bark of eucommia
12-20 grams of frankincense 5-12 grams of earthworm of 12-20 grams of myrrh.
Preferable amount is
15 grams of Radix Angelicae Sinensis, 12.5 grams of the root of Dahurain angelica, 12.5 grams of levisticum
9 grams of radix aconiti sinensis, 9 grams of RADIX ACONITI KUSNEZIFFII, 9 grams of pawpaw
12.5 grams of the root of bidentate achyranthes, 12.5 grams of the bark of eucommia, 9 grams of Radix Glycyrrhizae
9 grams of 12.5 grams of myrrhs of frankincense, 12.5 earthworm.
Preparation method of the invention is as follows
First, get the raw materials ready
1st, Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；
2nd, the root of Dahurain angelica：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, section
Dry；
3rd, levisticum：Impurity is picked, size is separated, cleaned, cut into slices after running through, dried；
4th, radix aconiti sinensis：Impurity is picked, ash bits are cleaned, dried；
5th, RADIX ACONITI KUSNEZIFFII：Crude drug is taken, impurity is removed, cleaning, drying, the used time smashs to pieces；
6th, pawpaw：Clear water is cleaned, and is slightly soaked, and vexed profit is put in food steamer and cooked to saturating, is cut into slices while hot, weather exposure, with by red turn of purple
Untill black；
7th, the root of bidentate achyranthes：Impurity is picked, is cleaned, softened, go reed, segment is dried；
8th, the bark of eucommia：Tertia is removed, is cleaned, run through, dice or strand are dried；
9th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；
10th, frankincense：Pick sand impurity；
11st, myrrh：Impurity is picked, fragment is broken into；
12nd, earthworm：Impurity is picked, is rinsed with water, pulled out in time, dried, segment.
2nd, prepare
1st, Radix Angelicae Sinensis, the root of Dahurain angelica, levisticum, radix aconiti sinensis, RADIX ACONITI KUSNEZIFFII, pawpaw, the root of bidentate achyranthes, the bark of eucommia, Radix Glycyrrhizae, frankincense, myrrh, the earthworm that will be cooked
Earthworm is ground into thin medicine end；
2nd, finely ground medicine end is put to iron pan, sprays 60 grams of yellow rice wine, made popular to be divided to and be bundled into two packs.
Levisticum has expelling wind and eliminating dampness in prescription, and the function of eliminating cold to stop pain is monarch drug in a prescription；The root of Dahurain angelica dispels pathogenic wind and remove dampness, the work(of swelling and pain relieving
Energy；RADIX ACONITI KUSNEZIFFII searches wind prevailing over dampness, and eliminating cold to stop pain opens the function of phlegm detumescence, and the two is ministerial drug, and three taste medicines are played and dissipate stagnation resolvation jointly
Swollen, active analgesic therapy, dispelling wind and eliminating dampness, the effect of promoting blood circulation for regulating menstruation, treatment rheumatic arthritis effect comprehensively, and with eliminating stasis to subdue swelling, dispel
Can be effected a permanent cure based on wind dehumidifying, active analgesic therapy；Pawpaw has suppressing the hyperactive liver and easing the stomach, and the function of the relaxing muscles and tendons that dries is adjutant；Radix Glycyrrhizae have with middle emergency,
To make medicine, remaining all medicines are to take stopgap measures to the function of coordinating the drug actions of a prescription.
The present invention has eliminating stasis to subdue swelling, active analgesic therapy, dispelling wind and eliminating dampness, the function of promoting blood circulation for regulating menstruation, is closed for treating rheumatic
The scorching good effect of section, has no side effect.
Beneficial effects of the present invention are expanded on further below by way of test example, these experiments include the dynamic of medicine of the present invention
Thing toxicity test and clinical observation on the therapeutic effect are tested.
[test example 1] animal toxicity test of the invention
West Germany rabbit 30 is taken, the belly rabbit hair is first pulled out and exposes skin only by male and female dual-purpose, body weight 2.0-2.5kg, the medicine that will be cooked
End is wrapped at rabbit belly baring skin, is then twined with gauze and is tied up parcel, and once a day, continuous 5 days, observation administration daily was anti-
Should, as a result showing that rabbit activity, diet are normal, medicine is without bad toxic and side effect.
[test example 2] experiment observation of curative effect of the invention
1st, physical data
Accept patient totally 32 for medical treatment.
2nd, diagnostic criteria
Rheumatic arthritis onset is more anxious, and affected joints start to invade and joint of lower extremity person accounts for 85% based on large joint, knee and ankle
Joint is most commonly seen, is secondly shoulder, elbow and wrist, and hand and sufficient Minor articulus are rare, and arthropathy is in multiple and migrans, joint
Local inflammation substantially, is presented with morning stiffness, dysfunction, arthroncus, tenderness and limitation of activity.
3rd, treatment method
Two packs that will be made popular press affected part in turn, press deposited 3-5 points at the position such as knee, ankle, wrist, hip or shoulder, elbow, joint successively
Clock, when medicine is not warm, then more medicine dressing change bag presses deposited, daily 2 times, 10 days 1 courses for the treatment of, is used in conjunction 3 courses for the treatment of.
4th, efficacy assessment standard
It is effective：Rheumatic arthritis symptom is controlled, recovery from illness.
Take a turn for the better：Rheumatoid arthritis disease becomes symptom mitigation, and arthroncus eliminates patient sign to be improved, and the state of an illness is progressively good
Turn.
It is invalid：Improvement standard person is not reached.
5th, efficacy result（See the table below）：
In above-mentioned treatment, with drug therapy rheumatoid arthritis patients of the present invention totally 32, as a result effective 29, obvious effective rate is
90.63%, take a turn for the better 2, improvement rate is 6.25%, and invalid 1, total effective rate is 96.88%.
Claims (3)
1. a kind of medicine for treating rheumatic arthritis, it is characterised in that：It is made up of the bulk drug in following weight range：
12-20 grams of Radix Angelicae Sinensis 10-15 grams of levisticum of 10-15 grams of the root of Dahurain angelica
5-12 grams of radix aconiti sinensis 5-12 grams of pawpaw of 5-12 grams of RADIX ACONITI KUSNEZIFFII
12-20 grams of root of bidentate achyranthes 5-12 grams of Radix Glycyrrhizae of 12-20 grams of the bark of eucommia
12-20 grams of frankincense 5-12 grams of earthworm of 12-20 grams of myrrh.
2. medicine according to claim 1, wherein the consumption of each bulk drug is：
15 grams of Radix Angelicae Sinensis, 12.5 grams of the root of Dahurain angelica, 12.5 grams of levisticum
9 grams of radix aconiti sinensis, 9 grams of RADIX ACONITI KUSNEZIFFII, 9 grams of pawpaw
12.5 grams of the root of bidentate achyranthes, 12.5 grams of the bark of eucommia, 9 grams of Radix Glycyrrhizae
9 grams of 12.5 grams of myrrhs of frankincense, 12.5 earthworm.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：
（One）Get the raw materials ready
（1）Radix Angelicae Sinensis：Impurity is picked, is cleaned, vexed profit is slightly dried in the air, and section is dried；
（2）The root of Dahurain angelica：Pick net impurity, wash, soak, pull out and run through, slightly shine to crust without soapy feeling when, then after vexed profit, cut
Piece is dried；
（3）Levisticum：Impurity is picked, size is separated, cleaned, cut into slices after running through, dried；
（4）Radix aconiti sinensis：Impurity is picked, ash bits are cleaned, dried；
（5）RADIX ACONITI KUSNEZIFFII：Crude drug is taken, impurity is removed, cleaning, drying, the used time smashs to pieces；
（6）Pawpaw：Clear water is cleaned, and is slightly soaked, and vexed profit is put in food steamer and cooked to saturating, is cut into slices while hot, weather exposure, with by red turn
Untill atropurpureus；
（7）The root of bidentate achyranthes：Impurity is picked, is cleaned, softened, go reed, segment is dried；
（8）The bark of eucommia：Tertia is removed, is cleaned, run through, dice or strand are dried；
（9）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, dry；
（10）Frankincense：Pick sand impurity；
（11）Myrrh：Impurity is picked, fragment is broken into；
（12）Earthworm：Impurity is picked, is rinsed with water, pulled out in time, dried, segment；
（Two）Prepare
（1）The Radix Angelicae Sinensis that to cook, the root of Dahurain angelica, levisticum, radix aconiti sinensis, RADIX ACONITI KUSNEZIFFII, pawpaw, the root of bidentate achyranthes, the bark of eucommia, Radix Glycyrrhizae, frankincense, myrrh,
Earthworm is ground into thin medicine end；
（2）Finely ground medicine end is put to iron pan, 60 grams of yellow rice wine is sprayed, is made popular and is obtained final product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611258280.1A CN106728099A (en) | 2016-12-30 | 2016-12-30 | It is a kind of to treat medicine of rheumatic arthritis and preparation method thereof |
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| CN201611258280.1A CN106728099A (en) | 2016-12-30 | 2016-12-30 | It is a kind of to treat medicine of rheumatic arthritis and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109248288A (en) * | 2018-11-28 | 2019-01-22 | 饶正军 | A kind of drug and preparation method thereof for treating rheumatism |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101327280A (en) * | 2008-07-26 | 2008-12-24 | 刘运波 | Chinese medicine for treating paralysis |
| CN102614265A (en) * | 2012-04-26 | 2012-08-01 | 河南中医学院 | Swelling-diminishing and pain-relieving self-emulsifying ointment |
-
2016
- 2016-12-30 CN CN201611258280.1A patent/CN106728099A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101327280A (en) * | 2008-07-26 | 2008-12-24 | 刘运波 | Chinese medicine for treating paralysis |
| CN102614265A (en) * | 2012-04-26 | 2012-08-01 | 河南中医学院 | Swelling-diminishing and pain-relieving self-emulsifying ointment |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109248288A (en) * | 2018-11-28 | 2019-01-22 | 饶正军 | A kind of drug and preparation method thereof for treating rheumatism |
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Application publication date: 20170531 |