CN106725451B - Human electrocardio R wave detecting system - Google Patents
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- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
- A61B5/346—Analysis of electrocardiograms
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
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- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
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- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
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Abstract
The invention provides a human body electrocardio R wave detection system which comprises a pulse wave signal acquisition module, a signal processing unit and a high-voltage pulse tumor treatment system, wherein the pulse wave signal acquisition module transmits acquired pulse information to the signal processing unit, the signal processing unit processes the received pulse signal and sends the processed pulse signal to a real-time display device and the high-voltage pulse tumor treatment system, and the high-voltage pulse tumor treatment system receives the signal to realize a discharge process. The pulse wave is an energy expression form taking blood flow as a carrier, the conduction of the pulse wave is not influenced by high-frequency high-voltage electric signals, the R wave moment can be calculated without waiting for recovery time in the treatment of high-voltage pulse tumor, the data is stable and reliable, the defect that the R wave is easily influenced by the high-voltage pulse signals in the detection of the traditional electrocardiograph lead method is avoided, and the risk of the high-voltage pulse to a patient in the operation process is reduced.
Description
Technical Field
The invention belongs to the technical field of medical equipment, and particularly relates to a human body electrocardio R wave detection system which is used for assisting the use of a high-voltage pulse tumor treatment device.
Background
The electrocardio is the comprehensive reflection of the depolarization process of innumerable cardiac myocytes of the heart, and bioelectric changes generated by cardiac muscles are reflected on the surface of the body through muscle, blood vessels, body fluid and other conductive tissues around the heart, so that each part of the body is subjected to regular electric change activities in each cardiac cycle. The term "myocardial cell depolarization" refers to the electrophysiological phenomenon of a cell, wherein the electric potential inside and outside the cell membrane of a normal cell is negative and positive, when an external electric stimulus is applied to the cell, ion channels at the point of action are opened, a large amount of positive charges enter the cell, so that the inside and outside of the cell membrane become negative and positive, at this time, a potential difference is generated between the point and the surrounding cell membrane, and an electric current is generated, and the electric stimulus spreads over the cell membrane until the whole cell membrane is depolarized, and then spreads to the cell membrane.
The treatment of tumors by using the irreversible electroporation effect of high-frequency pulses on tumor cells is a novel method for treating tumors in recent years (hereinafter referred to as a high-voltage discharge system). In the high-pressure high-frequency pulse tumor process, if the treatment part is close to the heart, the high-frequency pulse can influence the depolarization process of myocardial cells, so that the beating function of the heart is endangered. It is often desirable to cooperate with electrocardiographic detection devices to emit high frequency pulses during the R-R interval of the human electrocardiograph to minimize this effect.
However, under the high-voltage and high-frequency environment, the high-voltage uses the tissues around the electrode as conduction paths to greatly influence the depolarization process of the whole body electrocardiosignal conduction of the human body, so that the collected electrocardiosignals are often extremely disordered and even cannot be collected in a period of time after the electrode discharges. It is necessary to wait for tens of seconds or more for the electrocardiographic signal conduction to resume during the operation to guide the subsequent high-voltage discharge process.
The pulse wave also contains a large amount of characteristic information of heart pulsation of a human body, the characteristic information is conducted to the whole body along the arterial vessel wall, the conduction is not influenced by high-voltage high-frequency signals, the time from the start of the heart pulsation to the conduction of the pulse wave to a specific part of the human body is fixed according to the hemodynamic principle, and the generation time of the electrocardio R wave can be found out by deducing the heart pulsation process by means of the pulse wave data.
Disclosure of Invention
In view of the above, the present invention is directed to providing a human body electrocardiographic R-wave detection system for assisting a high-voltage pulse tumor treatment device, so as to provide a device capable of stably acquiring and calculating the heart beat state and giving the peak moment of R-wave.
In order to achieve the above purpose, the technical scheme of the invention is realized as follows:
the utility model provides a human electrocardio R wave detecting system, including pulse wave signal acquisition module, signal processing unit, high-pressure pulse tumour treatment system, pulse wave signal acquisition module gives signal processing unit with the pulse information transmission who gathers, signal processing unit sends real-time display device and high-pressure pulse tumour treatment system after handling the pulse signal that receives, realize discharging process after the high-pressure pulse tumour treatment system received the signal, in the operation process, fix pulse wave signal acquisition module to human skin surface, real-time detection human pulse wave data, combine the conduction time, calculate electrocardio R wave moment and give the signal of discharging, high-pressure pulse tumour treatment system receives the signal of discharging, carry out a set of work of discharging, afterwards high-pressure pulse tumour treatment system gets into wait state, until the arrival of next discharge signal.
Further, the pulse wave signal acquisition module comprises a photoelectric sensor, and the photoelectric sensor transmits acquired signals to the signal processing unit.
Further, the model of photoelectric sensor is JFH102, is provided with LED region and sensor region on the photoelectric sensor, is provided with the shading part that corresponds with photoelectric sensor on the photoelectric sensor, has seted up first light trap and second light trap on the shading part, and first light trap corresponds with the LED region, and the second light trap corresponds with the sensor region, is provided with the crossbeam that separates first light trap and second light trap between first light trap and the second light trap.
Further, the signal processing unit comprises a micro processor MCU, the pulse wave signal acquisition module transmits acquired signals to the micro processor MCU, the micro processor MCU transmits processed signals to the isolation circuit, and the isolation circuit transmits signal output to the high-voltage pulse tumor treatment system.
Further, the isolation circuit comprises a photoelectric coupler, a first light emitting diode, a first diode, a triode, a first resistor, a second resistor, a fourth resistor, a fifth resistor and a first capacitor, wherein the output end of the micro processor MCU is connected with one end of the fifth resistor, the other end of the fifth resistor is respectively connected with one end of the first capacitor and a second pin of the photoelectric coupler, the first pin of the photoelectric coupler and the other end of the first capacitor are respectively connected with a +5V power supply, the third pin of the photoelectric coupler is connected with one end of the fourth resistor, the other end of the fourth resistor is respectively connected with the base electrode of the triode and one end of the second resistor, the other end of the second resistor is grounded, the emitter electrode of the triode is grounded, the fourth pin of the photoelectric coupler is connected with one end of the first resistor, the other end of the first resistor is connected with the positive electrode of the first light emitting diode, the negative electrode of the first light emitting diode is connected with the collector electrode of the triode, the first resistor and the first diode are connected in parallel, the positive electrode of the first diode is connected with the negative electrode of the first light emitting diode, the first resistor and the other end of the first diode is connected with the positive electrode of the first light emitting diode, and the positive electrode of the first diode is connected with the positive electrode of the first diode, and the positive electrode of the first diode is connected with the positive electrode 12, and the positive electrode of the first diode is connected with the positive electrode of the power supply.
Compared with the prior art, the human body electrocardio R wave detection system provided by the invention has the following advantages:
(1) The pulse wave is an energy expression form taking blood flow as a carrier, and the conduction of the pulse wave is not influenced by high-frequency high-voltage electric signals, so that the R wave moment can be calculated without waiting for recovery time in the tumor treatment process, the data is stable and reliable, the defect that the R wave is easily influenced by high-voltage pulse signals in the detection of the traditional electrocardiograph method is avoided, and the risk of high-voltage pulse to a patient in the operation process is reduced;
(2) The invention is based on the MCU processing signal of the micro processor, acquires the pulse wave data of the human body at high speed, can realize the real-time monitoring and display of the pulse wave signal of the human body, and meets the requirement of real-time acquisition and display of the physiological data of the human body in the working process of the high-voltage discharge system.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention and do not constitute an undue limitation on the invention. In the drawings:
FIG. 1 is a schematic diagram of an inventive embodiment of the present invention;
FIG. 2 is a schematic diagram illustrating selection of characteristic points of electrocardiographic signals and pulse wave signals according to an embodiment of the present invention;
FIG. 3 is a schematic view of a photoelectric sensor according to an embodiment of the present invention;
FIG. 4 is a schematic view of a light shielding member according to an embodiment of the present invention;
fig. 5 is a circuit diagram of an isolation circuit according to an embodiment of the invention.
Reference numerals illustrate:
1-a photosensor; a 101-LED area; 102-a sensor region; 2-a light shielding member; 201-a first light hole; 202-second light holes.
Detailed Description
It should be noted that, without conflict, the embodiments of the present invention and features of the embodiments may be combined with each other.
In the description of the invention, it should be understood that the terms "center," "longitudinal," "transverse," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate orientations or positional relationships that are based on the orientation or positional relationships shown in the drawings, merely to facilitate describing the invention and simplify the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be configured and operate in a particular orientation, and therefore should not be construed as limiting the invention. Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first", "a second", etc. may explicitly or implicitly include one or more such feature. In the description of the invention, unless otherwise indicated, the meaning of "a plurality" is two or more.
In the description of the invention, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the creation of the present invention can be understood by those of ordinary skill in the art in a specific case.
The invention will be described in detail below with reference to the drawings in connection with embodiments.
As shown in fig. 1 to 5, the human body electrocardio R wave detection system comprises a pulse wave signal acquisition module, a signal processing unit and a high-voltage pulse tumor treatment system, wherein the pulse wave signal acquisition module transmits acquired pulse information to the signal processing unit, the signal processing unit processes the received pulse signal and sends the processed pulse signal to the real-time display device and the high-voltage pulse tumor treatment system, and the high-voltage pulse tumor treatment system receives the signal and then realizes a discharge process. The pulse wave signal acquisition module comprises a photoelectric sensor 1, and the photoelectric sensor 1 transmits acquired signals to the signal processing unit. The type of the photosensor 1 is JFH102, and the photosensor 1 is provided with an LED region 101 and a sensor region 102. In order to ensure that the external optical signal does not affect the photoelectric sensor 1 in the detection process, as a preferred scheme, a shading component 2 corresponding to the photoelectric sensor 1 is arranged on the photoelectric sensor 1, and the shading component 2 is attached to and surrounds the sensor. The shading component 2 is provided with a first light hole 201 and a second light hole 202, the first light hole 201 corresponds to the LED area 101, the second light hole 202 corresponds to the sensor area 102, and a beam for separating the first light hole 201 from the second light hole 202 is arranged between the first light hole 201 and the second light hole 202 and used for preventing scattering of emitted light. The signal processing unit comprises a micro processor MCU, and the pulse wave signal acquisition module transmits acquired signals to the micro processor MCU. Because the invention is used for the high-voltage pulse environment, the influence of a long lead on signal transmission is considered, and meanwhile, in order to reduce the coupling effect between a front stage circuit and a rear stage circuit, an isolation circuit (as shown in fig. 5) is added to a signal output part, the left Win3 is a signal input end, and the right WindDrive3 is a signal output end. The micro processor MCU transmits the processed signals to the isolation circuit, and the isolation circuit transmits the signal output to the high-voltage pulse tumor treatment system.
As shown in fig. 5, the isolation circuit includes a photo-coupler OP1, a first light emitting diode DA1, a first diode D1, a triode TA1, a first resistor R1, a second resistor R2, a fourth resistor R4, a fifth resistor R5, and a first capacitor CA1, where an output end of the micro-processor MCU is connected to one end of the fifth resistor R5, and another end of the fifth resistor R5 is connected to one end of the first capacitor CA1 and a second pin of the photo-coupler OP1, respectively. The other ends of the first pin of the photoelectric coupler OP1 and the first capacitor CA1 are respectively connected with a +5V power supply DVCC5. The third pin of the photoelectric coupler OP1 is connected with one end of a fourth resistor R4, and the other end of the fourth resistor R4 is respectively connected with the base electrode of the triode TA1 and one end of the second resistor R2. The other end of the second resistor R2 is grounded, and the emitter of the triode TA1 is grounded. The fourth pin of the photoelectric coupler OP1 is connected with one end of a first resistor R1, the other end of the first resistor R1 is connected with the positive electrode of a first light-emitting diode DA1, and the negative electrode of the first light-emitting diode DA1 is connected with the collector electrode of a triode TA 1. The first resistor R1 and the first light emitting diode DA1 are connected in parallel with a first diode D1, the positive electrode of the first diode D1 is connected with the negative electrode of the first light emitting diode DA1, and the junction of the photoelectric coupler OP1, the first resistor R1 and the first diode D1 is connected with a +12V power supply EVCC12. The collector of the triode TA1 is a signal output end.
A detection method of a human body electrocardio R wave detection system comprises the following steps:
step one: selecting a pulse wave collecting part, selecting a part with smooth skin surface, abundant subcutaneous arterial blood vessels and good permeability, such as a part with abundant fingertip, arm inner side or forehead subcutaneous arterial blood vessel tissues, and bonding and fixing a pulse wave signal collecting module to the surface of the selected part;
step two: measuring pulse wave conduction time and calibrating by using a traditional electrocardiograph lead system;
step three: the pulse wave signal acquisition module transmits signals to the signal processing signal unit, and the signal processing unit transmits the signals to the high-voltage pulse tumor treatment system, and the high-voltage pulse tumor treatment system performs a discharging process.
The working principle of the invention is as follows:
(1) Selecting a pulse wave collecting part, selecting a part with smooth skin surface, abundant subcutaneous arterial blood vessels and good permeability, attaching and fixing a sensor on the surface of the selected part, and selecting the part with abundant subcutaneous arterial blood vessel tissues such as fingertips, inner sides of arms or forehead and the like by the part generally recommended. The pulse wave signal acquisition module selects the photoelectric sensor 1, the principle is based on that the absorption effects of hemoglobin in blood on red light and infrared light are different, and the content of hemoglobin in blood is continuously changed along with the pulsation of a heart. The pulse wave detection method comprises the steps that a light source is integrated at the bottom of a photoelectric sensor 1, red light with the wavelength of 660nm is emitted at the frequency of 100HZ, an optical signal receiving area is arranged at the upper part of the photoelectric sensor, reflected optical signals containing human pulse waves are converted into electric signals and output in real time, the output signals are transmitted to an MCU processor through a connecting wire to be processed, characteristic values are identified, and a calculation result is output to a discharge device of a high-voltage pulse tumor treatment system through an isolation circuit.
(2) Pulse transit time is measured preoperatively and calibrated with conventional electrocardiographic lead system systems. In the calibration step, the electrocardio and pulse wave data are simultaneously acquired at the frequency of 500Hz, the R wave crest of the standard lead I electrocardio data is taken as the starting point of heart pulsation, the pulse wave crest is the characteristic point of pulse wave propagation to the acquisition point (see figure 2), and the time difference between the two is acquired and calculated by the MCU, namely the pulse wave conduction time.
(3) In the treatment process, the electrocardiograph data is not required to be detected, only pulse wave data is monitored in real time, the next R wave moment is obtained through algorithm calculation by combining the conduction time obtained in the steps, and a confirmation signal is given by the R wave detection system and is transmitted to the high-voltage discharge system.
(4) The high-voltage discharge system performs a set of discharge operations according to the given discharge signal, and then enters a waiting state until the next discharge signal arrives.
The above embodiments are merely preferred embodiments of the present invention and are not intended to limit the present invention, and any modifications, equivalent substitutions, improvements, etc. within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (3)
1. A human electrocardio R wave detecting system which is characterized in that:
the pulse wave signal acquisition module transmits the acquired pulse information to the signal processing unit, the signal processing unit processes the received pulse signal and sends the processed pulse signal to the real-time display device and the high-voltage pulse tumor treatment system, and the high-voltage pulse tumor treatment system receives the signal to realize the discharge process; the pulse wave signal acquisition module comprises a photoelectric sensor (1), and the photoelectric sensor (1) transmits acquired signals to the signal processing unit; the signal processing unit comprises a micro processor MCU, the pulse wave signal acquisition module transmits acquired signals to the micro processor MCU, the micro processor MCU transmits processed signals to the isolation circuit, and the isolation circuit transmits signal output to the high-voltage pulse tumor treatment system.
2. The human electrocardiographic R-wave detection system according to claim 1, wherein:
the type of photoelectric sensor (1) is JFH102, is provided with LED region (101) and sensor region (102) on photoelectric sensor (1), is provided with light shielding component (2) that correspond with photoelectric sensor (1) on photoelectric sensor (1), has seted up first light trap (201) and second light trap (202) on light shielding component (2), and first light trap (201) corresponds with LED region (101), and second light trap (202) corresponds with sensor region (102), is provided with the crossbeam that separates first light trap (201) and second light trap (202) between first light trap (201) and second light trap (202).
3. The human electrocardiographic R-wave detection system according to claim 1, wherein:
the isolation circuit comprises a photoelectric coupler (OP 1), a first light emitting diode (DA 1), a first diode (D1), a triode (TA 1), a first resistor (R1), a second resistor (R2), a fourth resistor (R4), a fifth resistor (R5) and a first capacitor (CA 1), wherein the output end of the micro processor MCU is connected with one end of the fifth resistor (R5), the other end of the fifth resistor (R5) is respectively connected with one end of the first capacitor (CA 1) and a second pin of the photoelectric coupler (OP 1), the first pin of the photoelectric coupler (OP 1) and the other end of the first capacitor (CA 1) are respectively connected with a +5V power supply (DVCC 5), the other end of the fourth resistor (R4) is respectively connected with one end of a base electrode of the triode (TA 1) and one end of the second resistor (R2), one end of the second resistor (R2) is grounded, the other end of the triode (TA 1) is respectively connected with one end of the first capacitor (CA 1) and the second pin of the first diode (TA 1), the first pin of the triode (TA 1) is connected with the first diode (TA 1) and the other end of the first diode (TA 1) in parallel with the first diode (DA 1) and the other end of the first diode (CA 1), the positive pole of the first diode (D1) is connected with the negative pole of the first light-emitting diode (DA 1), the photoelectric coupler (OP 1), the first resistor (R1) and the connection node of the first diode (D1) are connected with a +12V power supply (EVCC 12), and the collector electrode of the triode (TA 1) is a signal output end.
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| CN110677069B (en) * | 2019-10-31 | 2021-09-24 | 上海健康医学院 | High-voltage ultrashort pulse power supply for tumor ablation |
| CN113274119A (en) * | 2021-05-19 | 2021-08-20 | 北京金石翔宇科技有限公司 | Tumor ablation equipment and method applying ultrahigh-voltage positive-negative composite pulse electric field |
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| CN105997027A (en) * | 2016-06-15 | 2016-10-12 | 丽水市人民医院 | Wearable remote electrocardiogram monitoring system |
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