CN106693097B - A kind of blood purification flow equilibrium device and method - Google Patents

A kind of blood purification flow equilibrium device and method Download PDF

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Publication number
CN106693097B
CN106693097B CN201710096760.0A CN201710096760A CN106693097B CN 106693097 B CN106693097 B CN 106693097B CN 201710096760 A CN201710096760 A CN 201710096760A CN 106693097 B CN106693097 B CN 106693097B
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utricule
liquid
accommodating cavity
flow equilibrium
switch
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CN106693097A (en
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蒋顺忠
李丽
秦剑
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Guangzhou University
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Guangzhou University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • A61M1/1603Regulation parameters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1601Control or regulation
    • A61M1/1603Regulation parameters
    • A61M1/1611Weight of the patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621Constructional aspects thereof
    • A61M1/1635Constructional aspects thereof with volume chamber balancing devices between used and fresh dialysis fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • A61M2205/3334Measuring or controlling the flow rate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3379Masses, volumes, levels of fluids in reservoirs, flow rates
    • A61M2205/3396Reservoirs being alternately filled and emptied for measuring flow rate or delivered volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

A kind of blood purification flow equilibrium device, it includes the shell equipped with the first accommodating cavity and the second accommodating cavity spherical in shape or elliposoidal, two accommodating cavities are built-in with metering bag respectively, metering bag in first accommodating cavity includes by diaphragm separation and equal the first utricule and the second utricule of volume, metering bag in second accommodating cavity includes by diaphragm separation and the equal third utricule and the 4th utricule of volume, liquid entrance is respectively equipped on each utricule, catheter is separately connected on liquid entrance on first utricule and third utricule to lead to and meet at waste liquid inflow pipe and waste liquid effuser, it is separately connected catheter on liquid entrance on second utricule and the 4th utricule leads to and meet at fresh liquid stream and enters pipe and fresh liquid stream outlet pipe, the catheter has pipeline switch;Described two set and intracavitary are respectively equipped with pressure detector.Cross-infection is not only avoided that using the present invention, but also the flow equilibrium of dialyzate or displacement liquid or blood can be controlled.

Description

A kind of blood purification flow equilibrium device and method
Technical field
The present invention relates to technical field of medical equipment, and in particular to a kind of blood purification flow equilibrium device and method.
Background technique
Blood purification technology includes haemodialysis, filtration, absorption and plasma exchange etc., the most general with haemodialysis application Time.Patient renal function failure causes metabolic waste that cannot excrete, and the purpose of haemodialysis is mainly to remove patient's Metabolic waste, especially extra moisture.Excessive moisture is excluded by haemodialysis and is also referred to as ultrafiltration, and the amount of ultrafiltration needs accurate Measurement, to reach optimal dry weight after dialysis, the realization of ultrafiltration mainly has three big typical technologies on traditional technology: balance Chamber technology, dual pump technology and flowmeter technology, be all by accurately control flow into and out dialyzer dialysate flow it Difference realizes target ultrafiltration volume, wherein with the accurate ultrafiltration structure that big flow balance and ultrafiltrate pump combine be it is more, more typical, than As counter balance pocket technology, dual pump technology use be exactly above structure.Therefore it is real for establishing the platform of dialyzate big flow balance The premise of existing ultrafiltration.
Dialysis is flowed into and out by accurate flow meter modules control with the haemodialysis control unit that treasure (hundred is special) is representative The dialysate flow of device is detailed in document " Li Chaowei, Li Xiaodong, treasure hemo system ultra filtration unit working principle and breakdown maintenance, doctor Treat hygienic equipment, the 2nd phase in 2005 " and " Bao Juncheng etc., treasure AK96 haemodialysis control unit liquid channel system structure and function point Analysis, health care equipment, the 6th phase in 2013 ".It is more traditional and it is common that the control of two-way flow come in two sub-sections it is real It is existing, i.e. the structure that combines of balance system and ultrafiltrate pump, such as using the Nice Fei Sen as the haemodialysis control unit of representative using " counter balance pocket+ Ultrafiltrate pump " Lai Shixian, detailed schematic are Publication No. CN1872357A, and publication date is that the China on December 6th, 2006 is special Sharp " blood purification capacitance balance and ultrafiltration apparatus " is disclosed, uses the knot of two cavitys, eight solenoid valves of totally four interior rooms Structure, fresh liquid and waste liquid interval thin film mutually push, so that the flow of fresh liquid and waste liquid remains balance.Separately Have using day machine dress haemodialysis control unit as " dual pump+ultrafiltrate pump " structure of representative, compound pumping action is similar to counter balance pocket, and rises To the effect of flow equilibrium, principle such as " Xue Feng, DBB-26 water channel of hemodialysis machine figure principle analysis, medical equipment information, 3rd phase in 2004 " or " Dong Bin, day machine fill DBB-27C dialysis machine water route part basic principle, Chinese blood purification, 2015 6th phase " is disclosed, and fresh liquid and one, waste liquid interval Ceramic piston, left and right mutually push, again such that fresh liquid and waste liquid Flow remain balance.Publication No. CN102900664A, publication date are the Chinese patent " one on January 30th, 2013 Kind ballast pump " and Publication No. CN102895710A, publication date are that the Chinese patent on January 30th, 2013 is " a kind of continuous Flow equilibrium device " also discloses the balancing technique and method being applied in this kind of control devices.
Some common features of above-mentioned various methods or techniques are: 1, it is installed on complicated hemodialysis apparatus internal watercourses In structure;2, need the mechanically and electrically component of bulky complex;3, liquid is directly contacted with device, is only applicable to flow through dialyzate And blood of human body cannot be flowed through;4, the non-disposable use of pipeline sterilizes cleaning after needing each use.
Summary of the invention
The object of the present invention is to provide a kind of simple and reasonable blood purification flow equilibrium device and method, can Cross-infection is avoided, and the flow equilibrium of dialyzate or displacement liquid or blood can be controlled.
To achieve the above object, a kind of blood purification flow equilibrium device provided by the present invention comprising shell, institute Shell is stated equipped with the first accommodating cavity spherical in shape or elliposoidal and the second accommodating cavity, first accommodating cavity and second accommodates Chamber is built-in with metering bag respectively, and the metering bag in first accommodating cavity includes by diaphragm separation and equal the first capsule of volume Body and the second utricule, the metering bag in second accommodating cavity include by diaphragm separation and the equal third utricule of volume and the Four utricules, are respectively equipped with liquid entrance on each utricule, on the liquid entrance on first utricule and third utricule respectively Connection catheter, which leads to and meets at waste liquid, flows into pipe and waste liquid effuser, the liquid on second utricule and the 4th utricule into It is separately connected catheter in outlet leads to and meet at fresh liquid stream and enter pipe and fresh liquid stream outlet pipe, the catheter is opened with pipeline It closes;Pressure detector is respectively equipped in first accommodating cavity and the second accommodating cavity.
Preferably, the metering bag under full state is spherical in shape or elliposoidal, the metering bag middle part are provided with Diaphragm, the diaphragm under the first utricule or the second utricule or third utricule or the 4th utricule full state in half ellipsoidal surface or Hemisphere face shape, the volume of each utricule are respectively equal to the volume of the metering bag;It first accommodating cavity, the second accommodating cavity and is full of Shape, the size of metering bag under state match.
Preferably, the shell includes pedestal and upper cover, and the pedestal is equipped with semielliptical shape or hemispheric kerve, The upper lid is equipped with semielliptical shape or hemispheric inverted draw cut;It is common by closure upper cover and pedestal, the inverted draw cut and kerve Spherical or elliposoidal the first accommodating cavity or the second accommodating cavity are formed, first accommodating cavity and the second accommodating cavity are set to same On shell or different shell.
Preferably, it is articulated and connected between the upper cover and pedestal for side, the other side opposite with hinged side is by setting Set lock control opening and closing.
Preferably, the pedestal is equipped with the pipeline slot for accommodating catheter, is provided as pipeline on the pipeline slot The tubing clamp of switch.
Preferably, the waste liquid flows into pipe and fresh liquid stream enters that peristaltic pump is arranged on pipe.
Preferably, the blood purification flow equilibrium device further includes controller, the pipeline switch, peristaltic pump and pressure Force detector is connect with controller signals respectively.
The present invention also provides a kind of flow equilibrium method using above-mentioned blood purification flow equilibrium device, packets It includes:
Step 1: implementing liquid padding to first utricule, the 4th utricule, while to second utricule, the Three utricules implement liquid discharging operation, and second utricule, the intracorporal liquid of third capsule are discharged under the pressure of diaphragm;
Step 2: being cut after the pressure detector detects that the pressure in the first accommodating cavity and the second accommodating cavity rises sharply Pipeline switch is changed, liquid padding is implemented to the second utricule, third utricule, while liquid is implemented to the first utricule, the 4th utricule Body discharging operation, first utricule, the 4th intracorporal liquid of capsule are discharged under the pressure of diaphragm, when pressure detector is examined again It measures after the pressure in the first accommodating cavity and the second accommodating cavity rises sharply, switches pipeline switch, return step one.
Preferably, the pipeline switch includes feed liquor switch and liquid switchs out, in the step 1 or step 2, leads to It crosses and opens the corresponding feed liquor switch of each utricule, close the corresponding liquid switch out of each utricule, open waste liquid inflow pipe and enter with fresh liquid stream The peristaltic pump of pipe realizes the liquid padding to each utricule.
Preferably, in the step 1 or step 2, by opening the corresponding liquid switch out of each utricule, each capsule is closed The corresponding feed liquor switch of body, realizes the liquid discharging operation to each utricule.
A kind of blood purification flow equilibrium device and method provided by above-mentioned technical proposal, can be to blood purification process In relevant liquid, especially displacement liquid or blood samples of patients carry out flow control, since liquid is flowed in disposable In metering bag and its pipeline, in addition to metering bag and its pipeline, the other component of flow equilibrium device does not occur with fluid to be measured straight Contact, avoids mutually infecting, therefore both can be applied to dialyzate, applies also for displacement liquid and blood;The flow equilibrium Device designs two metering bags, utricule, the control utricule liquid of four same volumes flow out the eight pipeline switchs realization flowed into Flow equilibrium control, two equal utricules of each metering bag setting volume, realizes liquid by the mutual extrusion of two utricules Emptying, and the process that two utricules fill fluid to be measured is monitored by setting pressure detector, when pressure detector detects accommodating When intracavitary pressure rises sharply, show that the filling of a utricule is completed, and the intracorporal fluid to be measured discharge of another capsule is completed, and is controlled with this The balance of liquid outflow influx between two utricules is realized in the switching of pipeline switch;Pass through the design of two metering bags, Ji Nengshi Existing flow equilibrium control, and can guarantee the continuity of fresh liquid output;The flow equilibrium apparatus structure is simple, easy for installation, and And device does not need to clean, and can be directly mounted at the surface of other equipment, facilitates operation.
Detailed description of the invention
Fig. 1 is the partial structural diagram of blood purification of the invention with flow equilibrium device;
Fig. 2 is that a kind of liquid of flow equilibrium method of the invention flows to schematic diagram;
Fig. 3 is that another liquid of flow equilibrium method of the invention flows to schematic diagram.
Wherein, 1- shell, 101- pedestal, 102- upper cover, 103- kerve, 104- inverted draw cut, 105- pipeline slot, 2- first are accommodated Chamber, 3- metering bag, the first utricule of 301-, the second utricule of 302-, 303- third utricule, the 4th utricule of 304-, the disengaging of 305- liquid Mouthful, 306- pressure conduction area, 4- catheter, 501- waste liquid, which flows into, manages, and 502- waste liquid effuser, the fresh liquid stream of 601- enters pipe, 602- Fresh liquid stream outlet pipe, 7- pipeline switch, the first tubing clamp of 701-, the second tubing clamp of 702-, 703- third tubing clamp, 704- the 4th are managed The 5th tubing clamp of Lu Jia, 705-, the 6th tubing clamp of 706-, the 7th tubing clamp of 707-, the 8th tubing clamp of 708-, 8- pressure detection Device, 9- peristaltic pump.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Implement below Example is not intended to limit the scope of the invention for illustrating the present invention.
A kind of blood purification flow equilibrium device provided by the present invention comprising shell 1, the shell, which is equipped with, is in Spherical or elliposoidal the first accommodating cavity and the second accommodating cavity.First accommodating cavity and the second accommodating cavity are set to same housing Or on different shell.In the present embodiment, first accommodating cavity and the second accommodating cavity are divided into two identical casings.It please join Attached drawing 1 is read, is the partial structural diagram of blood purification flow equilibrium device, discloses the shell equipped with the first accommodating cavity 2 Structure.First accommodating cavity and the second accommodating cavity are built-in with metering bag 3 respectively, and the metering bag in first accommodating cavity includes By diaphragm separation and equal the first utricule 301 and the second utricule 302 of volume, the metering bag in second accommodating cavity includes By diaphragm separation and the equal third utricule 303 and the 4th utricule 304 of volume, liquid entrance is respectively equipped on each utricule 305, catheter 4, which is separately connected, on the liquid entrance on first utricule 301 and third utricule 303 leads to and meet at useless Liquid stream enters pipe 501 and waste liquid effuser 502, divides on the liquid entrance 305 on second utricule 302 and the 4th utricule 304 Not Lian Jie catheter 4 lead to and meet at fresh liquid stream and enter pipe 601 and fresh liquid stream outlet pipe 602, the catheter 4 has pipeline switch 7;Pressure detector 8 is respectively equipped in first accommodating cavity and the second accommodating cavity.
Flow equilibrium device of the invention is in use, since liquid is flowed in disposable metering bag and its pipeline In, in addition to metering bag and its pipeline, the other component of flow equilibrium device does not contact directly with fluid to be measured generation, avoids mutually Infection, therefore both can be applied to dialyzate, apply also for displacement liquid and blood;The flow equilibrium device passes through same accommodating The mutual extrusion of two intracavitary utricules realizes the emptying of liquid, and monitors two utricules by setting pressure detector and fill test solution The process of body shows that the filling of a utricule is completed when pressure detector detects that the pressure in accommodating cavity rises sharply, and another capsule Intracorporal fluid to be measured discharge is completed, and with the switching that this control piper switchs, realizes liquid outflow influx between two utricules Balance;By the design of two metering bags, it had not only been able to achieve flow equilibrium control, but also can guarantee the continuity of fresh liquid output;It is described Flow equilibrium apparatus structure is simple, easy for installation, and device does not need to clean, and can be directly mounted at the surface of other equipment, Facilitate operation.
In the present embodiment, the metering bag 3 under full state is spherical in shape or elliposoidal, in the middle part of the metering bag It is provided with diaphragm, the diaphragm is full of shape in the first utricule 301 or the second utricule 302 or third utricule 303 or the 4th utricule 304 It is in half ellipsoidal surface or hemisphere face shape under state, the volume of each utricule is respectively equal to the volume of the metering bag, with the appearance of metering bag Product is the volume of the flow equilibrium device;The shape of metering bag under first accommodating cavity, the second accommodating cavity and full state Shape, size match.For filling liquid to the first utricule 301, to the first utricule filling liquid until the first balloon inflation To maximum volume, when the first balloon inflation to maximum volume, the pressure detector 8 in the first accommodating cavity 2 detects the first appearance It sets in chamber 2, the pressure of especially metering bag 3 rises sharply.While filling liquid to the first utricule 301, the second utricule 302 is implemented Discharge liquor gymnastics is made, and liquid is smoothly discharged under the compressing of diaphragm for second utricule 302, when first utricule 301 is swollen It is swollen to maximum volume when, the liquid in the second utricule 302 is emptied completely.Similarly, when second utricule 302 is expanded to largest body When product, the liquid in the first utricule 301 is emptied completely.
In another embodiment of the invention, with the volume of first accommodating cavity or the second accommodating cavity for the flow The volume of balancing device, the first utricule 301, the second utricule 302, third utricule 303, the 4th utricule 304 volume be greater than or Equal to the first accommodating cavity or the volume of the second accommodating cavity.For filling liquid to the first utricule 301, filled to the first utricule When liquid, limitation is formed to the amount of liquid that the first utricule can fill by the inner wall of the first accommodating cavity, is filled out when in the first utricule When the amount of liquid filled reaches the volume of the first accommodating cavity, the pressure detector 4 in the first accommodating cavity is detected in the first accommodating cavity Pressure rise sharply.While filling liquid to the first utricule, the second utricule is implemented discharge liquor gymnastics and is made, and second utricule exists Liquid is smoothly discharged under the compressing of the inner wall of diaphragm and the first accommodating cavity.
Preferably, the pressure conduction area 306 convenient for pressure monitoring is provided on the metering bag 3, the pressure conduction area 306 Film thickness it is thicker relative to other regions, in favor of pressure transmitting.
The waste liquid flows into pipe 501 and fresh liquid stream enters setting peristaltic pump 9 on pipe 601, dynamic with the driving for providing liquid flowing Power.
Please refer to attached drawing 1, the shell 1 includes pedestal 101 and upper cover 102, the pedestal 101 be equipped with semielliptical shape or The hemispheric kerve 103 of person, the upper lid are equipped with semielliptical shape or hemispheric inverted draw cut 104;By being closed 102 He of upper cover Spherical or elliposoidal the first accommodating cavity or the second accommodating cavity is collectively formed in pedestal 101, the inverted draw cut 104 and kerve 103.? In the present embodiment, it is articulated and connected between the upper cover 102 and pedestal 101 for side, the other side opposite with hinged side passes through Setting lock control opening and closing.Since flow equilibrium device of the invention can be used as a part of blood cleaning equipment, this stream Amount balancing device can be embedded in or be otherwise coupled in the outside of blood cleaning equipment.In the other embodiment of the present invention In, the lid conjunction mode of the upper cover 102 of the shell 1 can link with the other component of blood cleaning equipment.In actual use process In, it can first be installed on the kerve of pedestal 103 after fixing metering bag 3, close lid 102 in lid.
The pedestal 101 is equipped with the pipeline slot 105 for accommodating catheter 4, is provided as pipe on the pipeline slot 105 The tubing clamp of way switch 7.The tubing clamp includes feed liquor switch and liquid switchs out, specifically, including the first utricule is arranged in The first tubing clamp 701 that liquid entrance and waste liquid flow between pipe 501, the liquid entrance and waste liquid that the first utricule is set The liquid entrance of the second utricule is arranged in and fresh liquid stream enters between pipe 601 in the second tubing clamp 702 between effuser 502 The 4th tubing clamp 704 between third tubing clamp 703, the liquid entrance that the second utricule is arranged in and fresh liquid stream outlet pipe 602 is set The liquid set the 5th tubing clamp 705 between liquid entrance and waste liquid the inflow pipe 501 of third utricule, third utricule is set Body inlet and outlet waste liquid effuser 502 between the 6th tubing clamp 706, be arranged in the 4th utricule liquid entrance and fresh liquid stream For entering the 7th tubing clamp 707 between pipe 601, being arranged between the liquid entrance of the 4th utricule and fresh liquid stream outlet pipe 602 Eight tubing clamps 708.The flow equilibrium device designs two metering bags, the utricule of four same volumes, control utricule liquid flow Eight tubing clamps flowed into out realize flow equilibrium control, utilize the flowing of eight tubing clamp control liquid.The tubing clamp can Using vein clamping structure well known to blood cleaning equipment industry, the tubing clamp is equipped with electromagnetic drive mechanism and corresponding control Circuit processed.
First accommodating cavity of this blood purification flow equilibrium device and the structure of the second accommodating cavity its fit system are as follows: from The pipeline that the first utricule extends out in first accommodating cavity and the pipeline that third utricule extends out out of second accommodating cavity are mutual Connection, for flowing through the waste liquid generated after dialysis;The pipeline that the second utricule extends out out of first accommodating cavity holds with from second It sets the pipeline that intracavitary 4th utricule extends out to be interconnected, for flowing through fresh liquid, in the present invention, the fresh liquid may include Analyse liquid, displacement liquid, new blood.
The blood purification flow equilibrium device further includes controller, and the pipeline switch 7, peristaltic pump 9 and pressure are visited Device 8 is surveyed to connect with controller signals respectively.The control circuit of this flow equilibrium device, for example, pipeline switch 7 control circuit and The control circuit of pressure detector 8, the unified setting of control circuit with blood cleaning equipment.It balances and controls for fluid flow When, this flow equilibrium device cooperates together with blood cleaning equipment.
Attached drawing 2 and 3 is please referred to, the present invention also provides a kind of using the above-mentioned blood purification flow of flow equilibrium device Balance method comprising:
Step 1: implementing liquid padding to first utricule, the 4th utricule, while to second utricule, the Three utricules implement liquid discharging operation, and second utricule, the intracorporal liquid of third capsule are discharged under the pressure of diaphragm;
Step 2: being cut after the pressure detector detects that the pressure in the first accommodating cavity and the second accommodating cavity rises sharply Pipeline switch is changed, liquid padding is implemented to the second utricule, third utricule, while liquid is implemented to the first utricule, the 4th utricule Body discharging operation, first utricule, the 4th intracorporal liquid of capsule are discharged under the pressure of diaphragm, when pressure detector is examined again It measures after the pressure in the first accommodating cavity and the second accommodating cavity rises sharply, switches pipeline switch, return step one.
The pipeline switch includes feed liquor switch and liquid switchs out, in the step 1 or step 2, passes through unlatching The corresponding feed liquor switch of each utricule, close each utricule it is corresponding go out liquid switch, open that waste liquid flows into pipe and fresh liquid stream enters the compacted of pipe Dynamic pump, realizes the liquid padding to each utricule.
In the step 1 or step 2, by opening the corresponding liquid switch out of each utricule, it is corresponding to close each utricule Feed liquor switch, realize to the liquid discharging operation of each utricule.
When for flow equilibrium, a flow equilibrium period can be divided into first half stage and rear half stage.Attached drawing 2 discloses The liquid in first half stage flows to: fresh liquid is driven by peristaltic pump reaches third tubing clamp 703 and the 7th tubing clamp 707, waste liquid by Peristaltic pump driving reaches at the first tubing clamp 701 and the 5th tubing clamp 705, the open and-shut mode of first half stage each tubing clamp are as follows: the One tubing clamp 701, the 4th tubing clamp 704, the 6th tubing clamp 706, the 7th tubing clamp 707 are opened, the second tubing clamp 702, third Tubing clamp 703, the 5th tubing clamp 705, the 8th tubing clamp 708 are closed.Therefore fresh liquid can flow into second from the 7th tubing clamp 707 The 4th utricule 304 in accommodating cavity pushes waste liquid from the third utricule 303 in the second accommodating cavity through the 6th pipe across one layer of diaphragm 706 outflow of road folder;Waste liquid can flow into the first utricule 301 in the first accommodating cavity from the first tubing clamp 701 simultaneously, across one layer Diaphragm pushes fresh liquid to flow out from the second utricule 302 in the first accommodating cavity through the 4th tubing clamp 704.
After the pressure detector in the first accommodating cavity and the second accommodating cavity detects that pressure increases, switch pipeline clip-like State, into the rear first half stage, attached drawing 3 disclose rear half stage liquid flow direction: the first tubing clamp 701, the 4th tubing clamp 704, 6th tubing clamp 706, the 7th tubing clamp 707 are closed, the second tubing clamp 702, third tubing clamp 703, the 5th tubing clamp 705, the Eight tubing clamps 708 are opened, therefore fresh liquid can flow into the second utricule 302 in the first accommodating cavity from third tubing clamp 703, across One layer of diaphragm pushes waste liquid to flow out from the first utricule 301 in the first accommodating cavity through the second tubing clamp 702;Waste liquid can be from simultaneously 5th tubing clamp 705 flows into the third utricule 303 in the second accommodating cavity, pushes fresh liquid out of second accommodating cavity across one layer of diaphragm The 4th utricule 304 through the 8th tubing clamp 708 flow out.
The discharge of fresh liquid each time is all that waste liquid is pushed across side film as a result, the fresh liquid being therefore discharged and entrance Waste liquid flow is equal, and similarly, the discharge of waste liquid each time is all that fresh liquid is pushed across side film as a result, being therefore discharged Waste liquid is equal with the fresh flow quantity of entrance.The result is that flow through the fresh flow quantity of device always with the waste liquid flow phase that flows through device Deng to realize the flow equilibrium of two-way liquid.
The flow equilibrium method contains liquid using disposable metering bag, so that the liquid that flows through and device Other component does not occur directly to contact, and can avoid mutually pollution, prevents cross-infection between patient, be both applicable to dialyzate, more It is applicable to displacement liquid and blood.In practical applications, by band, there are two two thin film metrology bags of utricule as container, benefit With 8 pipeline switchs, successively action control liquid flows, and switches using pressure detector detection occupied state as pipeline switch The foundation of movement realizes the flow equilibrium of the waste liquid and fresh liquid that flow through device, principle letter applied by the flow equilibrium device Single and its flow equilibrium method is realized reliable.
The above is only the preferred embodiment of the present invention, it is noted that those skilled in the art are come It says, without departing from the technical principles of the invention, several improvement and replacement can also be made, these are improved and replacement is also answered It is considered as protection scope of the present invention.

Claims (9)

1. a kind of blood purification flow equilibrium device, which is characterized in that it includes shell, the shell be equipped with it is spherical in shape or The first accommodating cavity and the second accommodating cavity of person's elliposoidal, first accommodating cavity and the second accommodating cavity are built-in with metering bag respectively, Metering bag in first accommodating cavity includes by diaphragm separation and equal the first utricule and the second utricule of volume described the Metering bag in two accommodating cavities includes by diaphragm separation and the equal third utricule and the 4th utricule of volume, on each utricule respectively Equipped with liquid entrance, catheter is separately connected on the liquid entrance on first utricule and third utricule and leads to and converges Pipe and waste liquid effuser are flowed into waste liquid, is separately connected catheter on the liquid entrance on second utricule and the 4th utricule Lead to and meet at fresh liquid stream and enter pipe and fresh liquid stream outlet pipe, the catheter has pipeline switch;First accommodating cavity and Pressure detector is respectively equipped in two accommodating cavities;The shell includes pedestal and upper cover, the pedestal be equipped with semielliptical shape or The hemispheric kerve of person, the upper lid are equipped with semielliptical shape or hemispheric inverted draw cut;It is described by closure upper cover and pedestal Spherical or elliposoidal the first accommodating cavity or the second accommodating cavity, first accommodating cavity and second is collectively formed in inverted draw cut and kerve Accommodating cavity is set on same housing or different shell.
2. blood purification as described in claim 1 flow equilibrium device, which is characterized in that the meter under full state Measure that bag is spherical in shape or elliposoidal, be provided with diaphragm in the middle part of the metering bag, the diaphragm in the first utricule or the second utricule or It is in half ellipsoidal surface or hemisphere face shape under third utricule or the 4th utricule full state, the volume of each utricule is respectively equal to the meter Measure the volume of bag;
First accommodating cavity, the second accommodating cavity and the metering bag under full state shape, size match.
3. blood purification as described in claim 1 flow equilibrium device, which is characterized in that be between the upper cover and pedestal Side articulated connection, the other side opposite with hinged side pass through setting lock control opening and closing.
4. blood purification as described in claim 1 flow equilibrium device, which is characterized in that the pedestal is equipped with for holding The pipeline slot of catheter is set, the tubing clamp of pipeline switch is provided as on the pipeline slot.
5. such as blood purification of any of claims 1-4 flow equilibrium device, which is characterized in that the waste liquid It flows into pipe and fresh liquid stream enters that peristaltic pump is arranged on pipe.
6. blood purification as claimed in claim 5 flow equilibrium device, which is characterized in that it further include controller, the pipe Way switch, peristaltic pump and pressure detector are connect with controller signals respectively.
7. a kind of flow equilibrium method using blood purification of any of claims 1-6 flow equilibrium device, It is characterized in that, comprising:
Step 1: implementing liquid padding to first utricule, the 4th utricule, while to second utricule, third capsule Body implements liquid discharging operation, and second utricule, the intracorporal liquid of third capsule are discharged under the pressure of diaphragm;
Step 2: after the pressure detector detects that the pressure in the first accommodating cavity and the second accommodating cavity rises sharply, switching pipe Way switch implements liquid padding to the second utricule, third utricule, while implementing liquid row to the first utricule, the 4th utricule It operates out, first utricule, the 4th intracorporal liquid of capsule are discharged under the pressure of diaphragm, when pressure detector detects again After pressure in first accommodating cavity and the second accommodating cavity rises sharply, switch pipeline switch, return step one.
8. flow equilibrium method as claimed in claim 7, which is characterized in that the pipeline switch includes feed liquor switch and liquid out Switch is switched by opening the corresponding feed liquor of each utricule in the step 1 or step 2, it is corresponding out to close each utricule Liquid switch opens the peristaltic pump that waste liquid flows into pipe and fresh liquid stream enters pipe, realizes the liquid padding to each utricule.
9. flow equilibrium method as claimed in claim 8, which is characterized in that in the step 1 or step 2, pass through The corresponding liquid switch out of each utricule is opened, the corresponding feed liquor switch of each utricule is closed, realizes the liquid discharging operation to each utricule.
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