CN106691619B - A kind of animal contusion of spinal cord ram - Google Patents
A kind of animal contusion of spinal cord ram Download PDFInfo
- Publication number
- CN106691619B CN106691619B CN201710095183.3A CN201710095183A CN106691619B CN 106691619 B CN106691619 B CN 106691619B CN 201710095183 A CN201710095183 A CN 201710095183A CN 106691619 B CN106691619 B CN 106691619B
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- CN
- China
- Prior art keywords
- pressure head
- animal
- spinal cord
- screw rod
- contusion
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Husbandry (AREA)
- Surgery (AREA)
- Surgical Instruments (AREA)
Abstract
The invention discloses a kind of animal contusion of spinal cord rams, lower platen is installed on base plate, guide rod is vertical between top board and lower platen, screw rod is set between two guide rods, lifting pedestal is set between top board and lower platen, lifting pedestal is equipped with first through hole corresponding with guide rod, the second through-hole corresponding with screw rod is additionally provided on lifting pedestal, first nut is set in the second through-hole, first nut is matched with screw rod, panel is set on base plate, cantilever is set to one end of lifting pedestal, pressure head is installed on the end of cantilever by pressure head attachment base, magnechuck is set to the top of pressure head, the connection or disconnection of pressure head and magnechuck are controlled by electromagnetic induction, electronic digital indicator is set on base plate and electronic digital indicator is located at the side of guide rod.The accuracy of hit position, the accuracy of hitting dynamics has been effectively ensured in the present invention, ensure that experiment effect and success rate, and it is at low cost, be easy to learn and use, be worthy to be popularized.
Description
Technical field
The present invention relates to zoopery equipment technology fields, and more specifically, in particular to a kind of animal contusion of spinal cord is hit
Hit device.
Background technique
The animal model of spinal cord injury is the important foundation for studying central nervous system injury and Regeneration and Repair.Currently used ridge
The animal model of marrow damage includes hitting, squeezing and the various forms such as cross-section.Wherein no matter the weight impact-model that falls is damaging
Physiological reaction and the pathophysiological change of secondary injury after form, or damage etc. can preferably simulate actual life
The spinal cord injury of middle people is most common acute spinal cord injury animal model.But existing spinal cord beating device or do not have
There is the device of fixed animal or only take into account the fixation of animal entirety, not specifically for quasi- by strike spinal segment position
The accurate fixed device of vertebral plate.And in actual operation operating process, if vertebral plate fixation is bad, when hitting spinal cord, it is easy to draw
The displacement of animal is played, and then drives the displacement of intraspinal tube spinal cord.On the one hand the dynamics actually hit and position be will cause and preset
Have deviation；The consequences such as the deviation that more importantly will cause between different animals individual increases, and experimental data is unstable.Cause
This, designs a animal contusion of spinal cord ram that can precisely fix vertebral plate, to experimental data it is reliable and stable have it is great
Meaning.
Summary of the invention
The purpose of the present invention is to provide a kind of structures simply, can precisely fix the animal contusion of spinal cord ram of vertebral plate.
In order to achieve the above object, The technical solution adopted by the invention is as follows:
A kind of animal contusion of spinal cord ram, including base plate, guide rod, top board, lifting pedestal, screw rod, magnechuck,
Pressure head, panel, pressure head attachment base, lower platen, the first nut, electronic digital indicator and cantilever；The lower platen is installed on pedestal
On plate, the guide rod is vertical between top board and lower platen, and the screw rod is set between two guide rods, the lifting pedestal
Between top board and lower platen, lifting pedestal is equipped with first through hole corresponding with guide rod, is additionally provided on lifting pedestal
The second through-hole corresponding with screw rod, first nut are set in the second through-hole, and first nut is matched with screw rod, institute
Panel is stated on base plate, the cantilever is set to one end of lifting pedestal, and the pressure head is installed on outstanding by pressure head attachment base
The end of arm, the magnechuck are set to the top of pressure head, by electromagnetic induction control pressure head and magnechuck connection or
It disconnects, the electronic digital indicator is set on base plate and electronic digital indicator is located at the side of guide rod.
Further, limit assembly is additionally provided on the panel, the limit assembly includes two limits being oppositely arranged
Unit, each position-limiting unit include support column, fixed link, screw part and pressing plate, and the support column is equipped with vertical
Limiting slot, the fixed link is horizontally through the limiting slot, and fixed link is fixed by screwing part, and the pressing plate is set to fixed link
Medial end.
Further, copper sheathing is additionally provided in the first through hole, the guide rod is matched with copper sheathing.
Further, end cap is arranged on the screw rod of the lifting pedestal upper end, the end cap uses hexagonal circle in first
Stud bolt is fixed.
Further, before the lower end of the electronic digital indicator is installed on slide calliper rule mounting base by slide calliper rule mounting plate
Side, the slide calliper rule mounting base are installed on base plate, and the display portion of the electronic digital indicator connects sealing plate by slide calliper rule
It is connected on slide calliper rule with slide calliper rule upper junction plate.
Further, the screw rod above the top board is equipped with wing nut, and the guide rod above the top board passes through
Third nut is fixed.
Further, it is additionally provided with deep groove ball bearing in second through-hole, the screw rod passes through after deep groove ball bearing with the
One nut matches.
Compared with the prior art, the advantages of the present invention are as follows: the accuracy of hit position, strike has been effectively ensured in the present invention
The accuracy of dynamics, ensure that experiment effect and success rate, and it is at low cost, be easy to learn and use, be worthy to be popularized.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with
It obtains other drawings based on these drawings.
Fig. 1 is the main view of animal contusion of spinal cord ram of the present invention.
Fig. 2 is the side view of animal contusion of spinal cord ram of the present invention.
Fig. 3 is the enlarged drawing in Fig. 1 of the present invention at A-A.
Fig. 4 is the top view of animal contusion of spinal cord ram of the present invention.
Fig. 5 is a kind of structural schematic diagram of pressing plate in animal contusion of spinal cord ram of the present invention.
Fig. 6 is another structural schematic diagram of pressing plate in animal contusion of spinal cord ram of the present invention.
Description of symbols: 1, base plate, 2, guide rod, 3, top board, 4, copper sheathing, 5, lifting pedestal, hexagonal in 6, first
Cylinder head bolt, six point cylindrical head bolt in 7, second, 8, slide calliper rule connect sealing plate, 9, slide calliper rule upper junction plate, 10, end cap, 11, spiral shell
Bar, 12, magnechuck, 13, pressure head, 14, panel, 15, pressure head attachment base, 16, limit assembly, 17, key, 18, hexagonal in third
Cylinder head bolt, six point cylindrical head bolt in the 19, the 4th, 20, lower platen, 21, elastic washer, the 22, first nut, 23, zanjon
Ball bearing, 24, electronic digital indicator, 25, slide calliper rule mounting plate, 26, slide calliper rule mounting base, the 27, second nut, 28, hex bolts,
29, wing nut, 30, third nut, 31, cantilever, 32, support column, 33, fixed link, 34, screw part, 35, pressing plate, 36, limit
Slot.
Specific embodiment
The preferred embodiment of the present invention is described in detail with reference to the accompanying drawing, so that advantages and features of the invention energy
It is easier to be readily appreciated by one skilled in the art, so as to make a clearer definition of the protection scope of the present invention.
Embodiment one
Refering to fig. 1 shown in-Fig. 4, the present invention provides a kind of animal contusion of spinal cord ram, including base plate 1, guide rod 2, on
Pressing plate 3, lifting pedestal 5, screw rod 11, magnechuck 12, pressure head 13, panel 14, pressure head attachment base 15, lower platen 20, the first spiral shell
Mother 22, electronic digital indicator 24 and cantilever 31.
The lower platen 20 passes through six point cylindrical head bolt 19 in the 4th and is installed on base plate 1, and hexagonal circle in the 4th
Be equipped with elastic washer 21 between stud bolt 19 and lower platen 20, the guide rod 2 be vertical at top board 3 and lower platen 20 it
Between, the screw rod 11 is set between two guide rods 2, and the lifting pedestal 5 is set between top board 3 and lower platen 20, goes up and down bottom
Seat 5 is equipped with first through hole corresponding with guide rod 2, is additionally provided with second through-hole corresponding with screw rod 11, institute on lifting pedestal 5
The first nut 22 is stated in the second through-hole, first nut 22 is matched with screw rod 11.
The panel 14 is set on base plate 1 by key 17, and the cantilever 31 passes through six point cylindrical head bolt 18 in third
Set on one end of lifting pedestal 5, the pressure head 13 is installed on the end of cantilever 31, the magnechuck by pressure head attachment base 15
12 are set to the top of pressure head 13, and the connection or disconnection of pressure head 13 and magnechuck 12, the digital display are controlled by electromagnetic induction
Vernier caliper 24 is set on base plate 1 and electronic digital indicator 24 is located at the side of guide rod 2.
It is additionally provided with limit assembly 16 on the panel 14, it can the upper and lower, dimension of front and rear, left and right three by limit assembly 16
Limit is adjusted, for fixing the vertebral plate of experimental animal (such as rat), to guarantee that the fixation of target spinal segment is not moved, protects
Demonstrate,prove the reliability of data.
The limit assembly 16 includes two position-limiting units being oppositely arranged, and each position-limiting unit includes support column
32, fixed link 33, screw part 34 and pressing plate 35, the support column 32 is equipped with vertical limiting slot 36, and the fixed link 33 is horizontal
To passing through the limiting slot 36, and fixed link 33 is fixed by screwing part 34, and the pressing plate 35 is set to the inner end of fixed link 33
Portion.
As shown in fig.5, the pressing plate 35 is L shape from the side, only one right angle can satisfy basic want
It asks.
Copper sheathing 4 is additionally provided in the first through hole, the guide rod 2 is matched with copper sheathing 4.
End cap 10 is arranged on the screw rod 11 of 5 upper end of lifting pedestal, the end cap 10 uses hexagonal cylindrical in first
Hook bolt 6 is fixed.
The lower end of the electronic digital indicator 24 (is consolidated by slide calliper rule mounting plate 25 by the second nut 27 and hex bolts 28
It is fixed) it is installed on the front side of slide calliper rule mounting base 26, the slide calliper rule mounting base 26 passes through six point cylindrical head bolt 7 in second and installs
In on base plate 1, the display portion of the electronic digital indicator 24 connects sealing plate 8 by slide calliper rule and slide calliper rule upper junction plate 9 connects
On slide calliper rule.
The screw rod 11 of 1 top of the top board is equipped with wing nut 29, and the guide rod 2 of 1 top of top board passes through the
Three nuts 30 are fixed, when in use, using rising or falling for 29 lifting controllable pedestal 5 of wing nut.
To further increase precision, deep groove ball bearing 23 is additionally provided in second through-hole, the screw rod 11 passes through zanjon
It is matched after ball bearing 23 with the first nut 22.
The working principle of animal contusion of spinal cord ram of the invention are as follows:
Beating device is placed on horizontal clean and tidy desktop by the first step, magnechuck 12 is powered on, so that pressure head 13
Into outer tube (not shown) (linear bearing is used between outer tube and pressure head, pressure head can be made to realize high sensitivity precision
High steady linear motion, utmostly reduces frictional force and the frictional force for guaranteeing that strike is suffered every time is consistent), and keep it electric
The magnechuck 12 of magnetic-inductive device, which adsorbs, to be fixed.
Second step, by the rat of the good specific hit position of spinal cord of exposure (or other suitable experimental animals, the present embodiment with
It is illustrated for rat) it is placed on panel 14.
Panel 14 is put on the base plate of beating device by third step, rat front-rear position is adjusted, so that pressure head 13 and rat
In same vertical line, up and down/left and right/front and back adjusts the vertebral plate (not shown) on panel 14 for spinal cord target damage position,
Position is accurate when pressing plate 35 hits the fixed guarantee of the vertebral plate of target position.
4th step, slowly rotation high-precision screw 11 (can be achieved 0.01mm height adjustment) make the scope of attack of pressure head 13 with
The endorchis on target spinal cord surface gently contacts, and presses lathe high-precision digital-display vernier caliper 24 (accuracy 0.01mm)
" ZERO " key, school zero.
Pressure head 13 is transferred to target strike height by the 5th step, rotation high-precision screw, is disconnected the power supply of magnechuck 12, is made
13 freely falling body of pressure head hits target spinal cord position, it is seen that the double hind legs of rat occur bouncing and macroscopic spinal cord beating
Position is in extravasated blood state and color is dimmed, and pressure head 13 is boosted after counting certain time (collision time of user's setting)
The outer tube of needle is hit, the power supply of magnechuck 12 is connected, is fixed so that pressure head 13 is adsorbed by magnechuck, in case strike next time
It uses.
6th step removes the rat after strike damage together with panel, carries out subsequent experimental procedure.
Embodiment two
As shown in fig.6, in actual use, because the vertebral plate of rat still has general 4-5mm's apart from skin
Distance, if structure of the pressing plate 35 using Fig. 5, pressing plate 35 is sometimes pressed not in place if directly subduing, and influences using effect.
Add a right angle effect can be quite a lot of down again on this basis thus, i.e., shape isThus can preferably it be imitated
Fruit.
In the use of the present invention, target part vertebra can be fixedly secured, the influence to animal breath and circulation is reduced, is reduced
Spinal cord blood supply reduces bring interference, and only preset strike damages, and improves animal survival rate.Electronic digital indicator can will beat
It hits high precision and guarantees the accuracy of strike height to 0.01mm, while there are a fixed gaps between pressure head and outer tube, can subtract
Friction between few pressure head and outer tube and the accuracy for guaranteeing hitting power.
The accuracy of hit position, the accuracy of hitting dynamics has been effectively ensured in the present invention, ensure that experiment effect and at
Power, and it is at low cost, be easy to learn and use, be worthy to be popularized.
Although the embodiments of the invention are described in conjunction with the attached drawings, but patent owner can be in appended claims
Within the scope of make various deformations or amendments, as long as it does not exceed the scope of protection described in the claims to the invention, all should
Within protection scope of the present invention.
Claims (6)
1. a kind of animal contusion of spinal cord ram, it is characterised in that: including base plate, guide rod, top board, lifting pedestal, screw rod,
Magnechuck, pressure head, panel, pressure head attachment base, lower platen, the first nut, electronic digital indicator and cantilever；The lower platen peace
Loaded on base plate, the guide rod is vertical between top board and lower platen, and the screw rod is set between two guide rods, described
Lifting pedestal is set between top board and lower platen, and lifting pedestal is equipped with first through hole corresponding with guide rod, lifting pedestal
On be additionally provided with the second through-hole corresponding with screw rod, first nut is set in the second through-hole, first nut and screw rod
It matches, the panel is set on base plate by key, and the cantilever is set to one end of lifting pedestal, and the pressure head passes through pressure head
Attachment base is installed on the end of cantilever, and the magnechuck is set to the top of pressure head, controls pressure head and electromagnetism by electromagnetic induction
The connection or disconnection of sucker, the electronic digital indicator is set on base plate and electronic digital indicator is located at the side of guide rod；
Limit assembly is additionally provided on the panel, the limit assembly includes two position-limiting units being oppositely arranged, each limit
Unit includes support column, fixed link, screws part and pressing plate, and the support column is equipped with vertical limiting slot, the fixed link
It is horizontally through the limiting slot, and fixed link is fixed by screwing part, the pressing plate is set to the medial end of fixed link, the pressure
The shape of plate is
2. animal contusion of spinal cord ram according to claim 1, it is characterised in that: be additionally provided with copper in the first through hole
Set, the guide rod are matched with copper sheathing.
3. animal contusion of spinal cord ram according to claim 1, it is characterised in that: the screw rod of the lifting pedestal upper end
On be arranged with end cap, the end cap is fixed using six point cylindrical head bolt in first.
4. animal contusion of spinal cord ram according to claim 1, it is characterised in that: the lower end of the electronic digital indicator
The front side of slide calliper rule mounting base is installed on by slide calliper rule mounting plate, the slide calliper rule mounting base is installed on base plate, the number
The display portion of aobvious vernier caliper connects sealing plate by slide calliper rule and slide calliper rule upper junction plate is connected on slide calliper rule.
5. animal contusion of spinal cord ram according to claim 1, it is characterised in that: the screw rod peace above the top board
Equipped with wing nut, the guide rod above the top board is fixed by third nut.
6. animal contusion of spinal cord ram according to claim 1, it is characterised in that: be additionally provided with depth in second through-hole
Ditch ball bearing, the screw rod match after passing through deep groove ball bearing with the first nut.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710095183.3A CN106691619B (en) | 2017-02-22 | 2017-02-22 | A kind of animal contusion of spinal cord ram |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710095183.3A CN106691619B (en) | 2017-02-22 | 2017-02-22 | A kind of animal contusion of spinal cord ram |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106691619A CN106691619A (en) | 2017-05-24 |
| CN106691619B true CN106691619B (en) | 2019-02-19 |
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ID=58917170
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710095183.3A Expired - Fee Related CN106691619B (en) | 2017-02-22 | 2017-02-22 | A kind of animal contusion of spinal cord ram |
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| Country | Link |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185589A (en) * | 2007-12-04 | 2008-05-28 | 中山大学 | Novel electric-controlled multi-use spinal cord beating device |
| CN101375810A (en) * | 2008-09-17 | 2009-03-04 | 北京航空航天大学 | Device for causing injury of laboratory animal |
| CN101485597A (en) * | 2009-03-03 | 2009-07-22 | 姜树东 | Injury striker for ventral side of spinal cord |
| CN201328880Y (en) * | 2008-11-17 | 2009-10-21 | 徐帆 | Simple model preparer for animals with spinal cord injuries |
| CN102379752A (en) * | 2011-08-22 | 2012-03-21 | 中南大学湘雅医院 | Automatic electric-control gravity-type striker for constructing acute spinal cord injury animal model |
| CN102871768A (en) * | 2012-09-25 | 2013-01-16 | 南京航空航天大学 | Big gecko's vertebral column three-dimensional positioning device and method |
| CN104739537A (en) * | 2015-04-03 | 2015-07-01 | 绍兴文理学院 | Animal spinal cord injury hitting device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1377248A2 (en) * | 2001-04-05 | 2004-01-07 | The Regents of the University of California | Robotic device for locomotor training |
-
2017
- 2017-02-22 CN CN201710095183.3A patent/CN106691619B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185589A (en) * | 2007-12-04 | 2008-05-28 | 中山大学 | Novel electric-controlled multi-use spinal cord beating device |
| CN101375810A (en) * | 2008-09-17 | 2009-03-04 | 北京航空航天大学 | Device for causing injury of laboratory animal |
| CN201328880Y (en) * | 2008-11-17 | 2009-10-21 | 徐帆 | Simple model preparer for animals with spinal cord injuries |
| CN101485597A (en) * | 2009-03-03 | 2009-07-22 | 姜树东 | Injury striker for ventral side of spinal cord |
| CN102379752A (en) * | 2011-08-22 | 2012-03-21 | 中南大学湘雅医院 | Automatic electric-control gravity-type striker for constructing acute spinal cord injury animal model |
| CN102871768A (en) * | 2012-09-25 | 2013-01-16 | 南京航空航天大学 | Big gecko's vertebral column three-dimensional positioning device and method |
| CN104739537A (en) * | 2015-04-03 | 2015-07-01 | 绍兴文理学院 | Animal spinal cord injury hitting device |
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| Publication number | Publication date |
|---|---|
| CN106691619A (en) | 2017-05-24 |
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