CN106691599B - Fear experiment stress device for laboratory mice - Google Patents
Fear experiment stress device for laboratory mice Download PDFInfo
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- CN106691599B CN106691599B CN201710095829.8A CN201710095829A CN106691599B CN 106691599 B CN106691599 B CN 106691599B CN 201710095829 A CN201710095829 A CN 201710095829A CN 106691599 B CN106691599 B CN 106691599B
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- rod
- vibrating
- hollow body
- vibrator
- fear
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/40—Animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/42—Evaluating a particular growth phase or type of persons or animals for laboratory research
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Abstract
The invention relates to a fear experiment stress device which can effectively solve the problems of complex operation and damage and even death of animals in the experiment process.
Description
Technical Field
The invention relates to the field of experimental equipment, in particular to an experimental fear experimental stress device for experimental mice.
Background
Along with the improvement of the living standard of people and the continuous perfection of medical system, the understanding of human beings on diseases is changed from a medical-biological mode to a medical-biological-psychological mode, and the study of stress is carried out, so that only the changes in the physiological and biochemical aspects of organisms are focused, and no excessive discussion is carried out on the psychological aspect of stress. As the sensitive period of female perception pressure, the pregnancy period has researches showing that the pregnancy period psychological stress not only affects the self health, but also affects the fetal emotion, cognition and other growth and development, so that the pregnancy period psychological stress is improved, the prenatal and postnatal care is improved, and the social significance is great. However, in the medical ethics, a psychological stress model is prepared through animal experiments to search a pathological mechanism, and most students at present perform experimental research by preparing a psychological stress model of 'kidney injury' through the Morris water maze principle to know that mice are afraid of water and can swim water to be natural, and fear emotion and strong urge to live are generated when the mice are in water. When the self-rescue climbing is carried out and the grasping is unstable, the fear emotion can be enhanced when strong light, vibration and terrorist sound stimulus are given to the self-rescue climbing and the self-rescue climbing falls into water again. However, the current fear stress animal model is harmful to experimental animals and even causes unexpected death, if a device can be designed to simulate the above-mentioned environment, a chronic fear stress experimental animal model can be manufactured while avoiding strong physical injury, so that the design of experimental equipment capable of effectively avoiding damage to experimental targets is a technical problem to be solved urgently.
Disclosure of Invention
Aiming at the situation, in order to overcome the defects of the prior art, the invention aims to provide the fear stress device for the laboratory mice, which can effectively solve the problems of complicated operation in the experimental process and damage and even death to animals in the experimental process.
The technical scheme includes that the fear stress device for the laboratory mice comprises a cross rod, a container and a vibrating rod, wherein the cross rod consists of a hollow rod in the middle, a first telescopic rod and a second telescopic rod in two ends, the cross rod is placed at an upper opening in the middle of the container, holes for hooks are uniformly distributed on the cross rod, the vibrating rod is hung on the holes through the hooks, the vibrating rod is a hollow body with a rough appearance and a sliding slot hole on one side, a vibrator is arranged at the bottom of the hollow body, a battery is arranged at the upper part of the hollow body, an alarm and a pressure switch are arranged on the side wall of the hollow body, the pressure switch is provided with a plurality of parallel-connected rods which are uniformly distributed on the peripheral wall of the vibrating rod (only one is shown in the figure), the anode of the battery is connected with the alarm and the pressure switch in series through a first wire at one end of the vibrator, the other end of the vibrator is connected with the cathode of the battery through a second wire and a sliding rheostat arranged on the inner side wall of the hollow body to form a vibrating loop of the vibrating rod, and an insulating cap extending out of the sliding slot hole is sleeved on a sliding sheet of the rheostat.
The invention has simple structure, novel and unique structure, convenient and safe use, can be suitable for various experimental mice, and has good social and economic benefits.
Drawings
FIG. 1 is a cross-sectional view of the structure of the present invention;
fig. 2 is a perspective view of the present invention.
Description of the embodiments
The following describes the embodiments of the present invention in detail with reference to the drawings.
The invention is shown in figures 1-2, which comprises a cross rod 1, a container 2 and a vibrating rod 3, wherein the cross rod 1 consists of a hollow rod in the middle and a first telescopic rod 1a and a second telescopic rod 1b in two ends, the cross rod is placed at the upper opening in the middle of the container 2, holes 4 for hooks are uniformly distributed on the cross rod 1, the vibrating rod 3 is hung on the holes 4 through the hooks 5, the vibrating rod 3 is a hollow body with a rough appearance and a slide slot 14 on one side, a vibrator 6 is arranged in the bottom of the hollow body, a battery 7 is arranged in the upper part of the hollow body, an alarm 9 and a pressure switch 10 are arranged on the side wall of the hollow body, a plurality of parallel connection parts are uniformly distributed on the peripheral wall of the vibrating rod 3 (only one is shown in the figure), the positive electrode of the battery 7 is connected with the alarm 9 and the pressure switch 10 in series at one end of the vibrator 6 through a first lead wire 8, the other end of the vibrator 6 is connected with the negative electrode of the battery 7 through a second lead wire 11 and a slide rheostat 12 arranged on a side wall fixing frame 16 in the hollow body, so as to form a vibrating loop of the vibrating rod 3, a slide cap 14 is sleeved on the slide rheostat 12, and a slide cap 14 is sleeved on the slide 13 extends out of the slide slot 13.
In order to ensure the use effect and the use convenience, the vibrating rod 3 is hollow and oblong or square.
When the invention is used, the stretching cross rod is firstly adjusted to be long enough to be carried on the upper edge of the experiment container, then the liquid level in the container is adjusted to be a height which does not cause the drowning of rats and the falling of rats from the vibrating rod, the power of the vibrators is adjusted by hanging vibrators with the corresponding quantity and body types according to the quantity and the body types of the experiment rats, then the experiment rats are placed in the container, the experiment rats struggled in water can climb on the device above the liquid level, a plurality of pressure switches can ensure that the circuit of the rats can be closed when the rats climb on the vibrating rod, at that time, the vibrators and the alarm lamps can trigger vibration and generate terrorist acousto-optic stimulation to the experiment rats, the experiment rats can fall into the water after being frightened, climbing objects can be searched again to implement self rescue after struggling in the water, and the experiment rats are cycled, and thus a chronic fear psychological stress state is formed.
The invention has novel and unique structure, simple operation and convenient and safe use, can effectively avoid the occurrence of injury and even death of the experimental mice, and is an innovation on a simple chronic fear psychological stress model.
Claims (2)
1. The fear stress device for the laboratory mice comprises a cross rod (1), a container (2) and a vibrating rod (3), and is characterized in that the cross rod (1) consists of a hollow rod in the middle and a first telescopic rod (1 a) and a second telescopic rod (1 b) in two ends, the cross rod is arranged at an upper opening in the middle of the container (2), holes (4) for hanging hooks are uniformly distributed on the cross rod (1), the vibrating rod (3) is hung on the holes (4) through the hanging hooks (5), the vibrating rod (3) is a hollow body with a rough appearance and a sliding slot hole (14) on one side, a vibrator (6) is arranged in the bottom of the hollow body, a battery (7) is arranged in the upper part of the hollow body, an alarm (9) and a pressure switch (10) are arranged on the side wall of the hollow body, a plurality of parallel-connected uniformly on the outer peripheral wall of the vibrating rod (3), the positive electrode of the battery (7) is connected with the alarm (9) and the pressure switch (10) in series through a first wire (8) at one end of the vibrator (6), the other end of the vibrator (6) is connected with a vibrating resistor (12) through a second wire (11) and a vibrating loop (12) arranged on the side wall of the vibrating rod (3) in the hollow body, an insulating cap body (13) extending out of the slide slot hole (14) is sleeved on a slide piece (15) of the slide rheostat (12).
2. The fear stress device for laboratory mice as claimed in claim 1, wherein the vibrating rod (3) is a hollow oblong or square shape.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710095829.8A CN106691599B (en) | 2017-02-22 | 2017-02-22 | Fear experiment stress device for laboratory mice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710095829.8A CN106691599B (en) | 2017-02-22 | 2017-02-22 | Fear experiment stress device for laboratory mice |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106691599A CN106691599A (en) | 2017-05-24 |
| CN106691599B true CN106691599B (en) | 2023-10-13 |
Family
ID=58917275
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710095829.8A Active CN106691599B (en) | 2017-02-22 | 2017-02-22 | Fear experiment stress device for laboratory mice |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106691599B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111436396A (en) * | 2020-04-24 | 2020-07-24 | 军事科学院军事医学研究院环境医学与作业医学研究所 | Method for establishing rat fear stress and gaseous pollutant composite exposure model |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006080087A1 (en) * | 2005-01-31 | 2006-08-03 | Takanobu Yamamoto | Method of screening antistress substance and antistress agent |
| CN201564985U (en) * | 2009-12-31 | 2010-09-01 | 西安交通大学口腔医院 | Psychological stress box for experimental use on small animals |
| CN202637176U (en) * | 2012-05-09 | 2013-01-02 | 中国人民解放军第三军医大学第三附属医院 | Device for trauma stress experiment |
| CN104622584A (en) * | 2015-03-13 | 2015-05-20 | 河南中医学院 | Animal chronic fear stress meter based on danger method |
| CN207202943U (en) * | 2017-02-22 | 2018-04-10 | 河南中医药大学 | A kind of frightened experiment stress device |
-
2017
- 2017-02-22 CN CN201710095829.8A patent/CN106691599B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006080087A1 (en) * | 2005-01-31 | 2006-08-03 | Takanobu Yamamoto | Method of screening antistress substance and antistress agent |
| CN201564985U (en) * | 2009-12-31 | 2010-09-01 | 西安交通大学口腔医院 | Psychological stress box for experimental use on small animals |
| CN202637176U (en) * | 2012-05-09 | 2013-01-02 | 中国人民解放军第三军医大学第三附属医院 | Device for trauma stress experiment |
| CN104622584A (en) * | 2015-03-13 | 2015-05-20 | 河南中医学院 | Animal chronic fear stress meter based on danger method |
| CN207202943U (en) * | 2017-02-22 | 2018-04-10 | 河南中医药大学 | A kind of frightened experiment stress device |
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| Publication number | Publication date |
|---|---|
| CN106691599A (en) | 2017-05-24 |
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