CN106691555A - Template for producing antibiotic-loaded bone cement bead chains - Google Patents
Template for producing antibiotic-loaded bone cement bead chains Download PDFInfo
- Publication number
- CN106691555A CN106691555A CN201611206526.0A CN201611206526A CN106691555A CN 106691555 A CN106691555 A CN 106691555A CN 201611206526 A CN201611206526 A CN 201611206526A CN 106691555 A CN106691555 A CN 106691555A
- Authority
- CN
- China
- Prior art keywords
- antibiotic
- template
- bone cement
- template body
- loaded bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000003115 biocidal effect Effects 0.000 title claims abstract description 52
- 239000002639 bone cement Substances 0.000 title claims abstract description 38
- 239000011324 bead Substances 0.000 title abstract 6
- 229910000831 Steel Inorganic materials 0.000 claims abstract description 18
- 239000010959 steel Substances 0.000 claims abstract description 18
- 239000000463 material Substances 0.000 claims abstract description 5
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 6
- 238000007493 shaping process Methods 0.000 claims description 2
- 238000001356 surgical procedure Methods 0.000 abstract description 6
- 208000002565 Open Fractures Diseases 0.000 abstract description 4
- 206010031252 Osteomyelitis Diseases 0.000 abstract description 2
- 206010062255 Soft tissue infection Diseases 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 239000004809 Teflon Substances 0.000 abstract 1
- 229920006362 Teflon® Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000011049 pearl Substances 0.000 description 29
- 208000015181 infectious disease Diseases 0.000 description 8
- 210000000988 bone and bone Anatomy 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 230000002980 postoperative effect Effects 0.000 description 4
- 239000007787 solid Substances 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 2
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 2
- 229930182566 Gentamicin Natural products 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 229960002518 gentamicin Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000004810 polytetrafluoroethylene Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- 206010061623 Adverse drug reaction Diseases 0.000 description 1
- 241001146209 Curio rowleyanus Species 0.000 description 1
- -1 Polytetrafluoroethylene Polymers 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000000692 anti-sense effect Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009415 formwork Methods 0.000 description 1
- 238000011540 hip replacement Methods 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 231100000816 toxic dose Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B2017/564—Methods for bone or joint treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0205—Materials having antiseptic or antimicrobial properties, e.g. silver compounds, rubber with sterilising agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/04—General characteristics of the apparatus implanted
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to a template for producing antibiotic-loaded bone cement bead chains. The antibiotic-loaded bone cement bead chains are surgery auxiliary instruments for preventing bone and soft tissue infection after open fracture surgery. The template comprises elastic clamp plates, an upper template body, a lower template body and positioning pins, wherein bead chain forming holes, steel wire and guide grooves and the positioning pin holes are arranged in each of the upper template body and the lower template body, and the upper template body and the lower template body are used for manufacturing the formed antibiotic-loaded bone cement bead chains; each elastic clamp plate is provided with a fixing chucks and provided with a clamp groove allowing the templates to pass; each elastic clamp plate has a dip angle so as to conveniently pressurize the upper template body and the lower template body; the upper template body and the lower template body are made of polymer teflon materials and can be easily separated for the bead chains.
Description
Technical field
It is a kind of mould for producing antibiotic-loaded bone cement chain pearl the present invention relates to a kind of antibiotic-loaded bone cement chain pearl template
Plate, antibiotic-loaded bone cement chain pearl be used for open fracture operation in or POI treatment, to prevent Postoperative Bone with soft group
Knit the surgery assistive device of infection.
Background technology
Open wound or Post operation bone and the infection of soft tissue are one of serious complication of orthopaedics, due to lesion bone
Tissue and its Peripheral blood poor and scar of fortune are more, and affected area antibiotic concentration and blood middle concentration are simultaneously not parallel, often below
The latter.Even if whole body application heavy dose antibiotic, is also difficult to reach effective antibiotic concentration in focus local organization.
Therefore, for many years, the treatment of bone and the sexy dye of arthro-empyesis is always a great problem in Orthopedic Clinical.Until celebrating
Big mycin bone cement is applied successfully to treat and prevent the infection of hip replacement, makes the localized sustained of antibiotic antibacterial
It is possibly realized, not only can persistently administers locally to effective antibiotic, and also avoid in the past to improve focus part group
It is woven with effect antibiotic concentration and increases drug toxicity and side effect that systemic dosage is brought.In fact, even if for antibiotic
Whole body gives toxic dose also be not as obvious as local low dose of role.
Multiple studies have shown that local auxiliary can reduce the infection rate of open fracture using filling gentamicin pelletron, but
It is that present gentamicin pelletron one is that antimicrobial spectrum resistance occurs, two is that import finished product is somewhat expensive like a chain of pearls or a string of beads, therefore can be according to medicine
Quick experiment and experience medication are voluntarily configured, and different antibiotic pelletrons are made when according to operation.
The content of the invention
The purpose of the present invention is directed to above-mentioned weak point and provides a kind of antibiotic-loaded bone cement chain pearl template, antibiotic bone water
Rationally, simple structure is easy to use for mud chain pearl stencil design, the antibiotic bone water produced using antibiotic-loaded bone cement chain pearl template
Mud chain pearl, makes operation technique convenient, and manufacturing cost is cheap, reduces the pain of patient, is easy to post-operative recovery.
Antibiotic-loaded bone cement chain pearl template of the present invention takes following technical scheme to realize：
Antibiotic-loaded bone cement chain pearl template includes elastic clamp, upper die plate, lower template and alignment pin.
Described upper die plate and lower template is internally provided with pelletron shaped hole, steel wire trough and guiding gutter, dowel hole, is used for
Make the antibiotic pelletron of shaping；
Described elastic clamp is provided with fixed chuck, and elastic card intralamellar part is provided with the draw-in groove of template.
Described elastic clamp set it is internal have draw-in groove, by its internal draw-in groove be used for from both sides pressurize it is closing up,
Lower template, is allowed to keep pressurization during solid, and elastic clamp is provided with inclination angle, to be pressurizeed to upper die plate and lower template.
Described upper die plate and lower template is made of high molecular weight ptfe material, can be easier and pelletron point
From.
Operation principle：
When antibiotic-loaded bone cement chain pearl template is used, according in the middle of surgical procedure, it is necessary to be carried out to infection site using antibiotic
Anti-inflammatory, bolster is laid flat, and the finer wire of winding is put into any one template steel wire trough and guiding gutter, and scene mixes anti-sense
The antibiotic-loaded bone cement medicine of dye, in the pelletron shaped hole then it being uniformly painted into template by scraper plate, waits two pieces of templates
Completion is all painted into, by it altogether, alignment pin is then inserted by the alignment pin control in template, to ensure that it up and down can be complete
It coincide.
When above-mentioned steps are all completed, elastic clamp is taken out, be used to pressurize what is closed up from both sides by its internal draw-in groove
Polytetrafluoroethylene (PTFE) template, is allowed to keep pressurization during solid, and elastic clamp has slight inclination angle, to pressurize, takes out clamp
And any one piece of template, extract steel wire, antibiotic-loaded bone cement chain pearl（Pelletron）Just being attached on steel wire one by one, finally by it
It is put into infection site.
Rationally, simple structure implants easy to use antibiotic-loaded bone cement chain pearl stencil design of the present invention, takes out just
It is prompt.It is easy to produce antibiotic-loaded bone cement chain pearl, the antibiotic-loaded bone cement chain pearl produced using antibiotic-loaded bone cement chain pearl template is used
In in open fracture Post operation, in order to prevent the surgery assistive device of Postoperative Bone and soft tissue infection.Make operation technique convenient,
The pain of patient is significantly reduced, is easy to post-operative recovery.
Brief description of the drawings：
Below with reference to accompanying drawing, the invention will be further described.
Fig. 1 is antibiotic-loaded bone cement chain pearl formwork structure schematic diagram.
Fig. 2 is the elastic card plate structure schematic diagram of antibiotic-loaded bone cement chain pearl template.
Fig. 3 is the upper die plate structural representation of antibiotic-loaded bone cement chain pearl template.
Fig. 4 is the lower template structural representation of antibiotic-loaded bone cement chain pearl template.
Marked in figure as follows：
1st, elastic clamp, 1-1, fixed chuck, 1-2, draw-in groove；2nd, upper die plate, 2-1 pelletron shaped holes, 2-2, steel wire trough and water conservancy diversion
Groove, 2-3, dowel hole, 3, alignment pin, 4, lower template, 4-1, pelletron shaped hole, 4-2, steel wire trough and guiding gutter, 4-3, positioning
Pin-and-hole.
Specific embodiment
Referring to the drawings 1,2,3,4, antibiotic-loaded bone cement chain pearl template include elastic clamp 1, upper die plate 2, alignment pin 3, under
Template 4.
Referring to the drawings 3, the upper die plate 2 of antibiotic-loaded bone cement chain pearl template is provided with pelletron shaped hole 2-1, steel wire trough and leads
Chute 2-2 and dowel hole 2-3, is primarily used to make antibiotic-loaded bone cement chain pearl（Pelletron）It is used.Steel wire trough and guiding gutter
2-2 can be integrated, and steel wire, antibiotic-loaded bone cement liquid medicine flow are placed during antibiotic-loaded bone cement chain pearl for making.
Referring to the drawings 4, the lower template 4 of antibiotic-loaded bone cement chain pearl template is provided with pelletron shaped hole 4-1；Steel wire trough and lead
Chute 4-2；Dowel hole 4-3, is primarily used to make antibiotic-loaded bone cement chain pearl（Pelletron）It is used.Steel wire trough and water conservancy diversion
Groove 4-2 can be integrated, and steel wire, antibiotic-loaded bone cement liquid medicine flow are placed during antibiotic-loaded bone cement chain pearl for making.
The elastic clamp 1 described in 2 is provided with fixed chuck 1-1 referring to the drawings, and elastic clamp 1 is internally provided with by template
Draw-in groove 1-2.
Described elastic clamp 1 sets inside draw-in groove, is used to pressurize what is closed up from both sides by its internal draw-in groove
Template 2, lower template 4, are allowed to keep pressurization during solid, and elastic clamp is provided with inclination angle, so as to upper die plate 2, lower template 4
Pressurization；
Described upper die plate 2 and the template of lower template 4 is made of high molecular weight ptfe material.Described upper die plate 2 is with
Template 4 is made of high molecular weight ptfe material, can be easier to be separated with pelletron.
When antibiotic-loaded bone cement chain pearl template is used, according in the middle of surgical procedure, it is necessary to using antibiotic to infection site
Anti-inflammatory is carried out, upper die plate 2, lower template 4 are laid flat, the thin of winding is put into any one template steel wire trough and guiding gutter 2-2 or 4-2
Steel wire, scene mixes anti-infectious antibiotic-loaded bone cement medicine, and then it be uniformly painted into the pelletron in template by scraper plate
In shaped hole 2-1 and 4-1, two pieces of templates are waited all to be painted into completion, by it altogether, then by the dowel hole 2-3 in template
Alignment pin 3 is inserted with 4-3, to ensure that it is spherical in shape that it can fit like a glove up and down.
When above-mentioned steps are all completed, elastic clamp 1 is taken out, be used to pressurize what is closed up from both sides by its internal draw-in groove
Upper die plate 2 and lower template 4, are allowed to keep pressurization during solid, and elastic clamp has slight inclination angle, to pressurize, take out card
Plate and any one piece of template, extract steel wire, antibiotic pelletron just being attached on steel wire one by one, finally put it into infection portion
Position.
Claims (3)
1. a kind of antibiotic-loaded bone cement chain pearl template, it is characterised in that：Including including elastic clamp, upper die plate, lower template and fixed
Position pin；
Described upper die plate and lower template is internally provided with pelletron shaped hole, steel wire trough and guiding gutter, dowel hole, for making
The antibiotic pelletron of shaping；
Described elastic clamp is provided with fixed chuck, and elastic card intralamellar part is provided with the draw-in groove of template.
2. a kind of antibiotic-loaded bone cement chain pearl template according to claim 1, it is characterised in that：Described elastic clamp sets
There is inclination angle, to be pressurizeed to upper die plate and lower template.
3. a kind of antibiotic-loaded bone cement chain pearl template according to claim 1, it is characterised in that：Described upper die plate is with
Template is made of high molecular weight ptfe material, can be easier to be separated with pelletron.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611206526.0A CN106691555A (en) | 2016-12-23 | 2016-12-23 | Template for producing antibiotic-loaded bone cement bead chains |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611206526.0A CN106691555A (en) | 2016-12-23 | 2016-12-23 | Template for producing antibiotic-loaded bone cement bead chains |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106691555A true CN106691555A (en) | 2017-05-24 |
Family
ID=58903109
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611206526.0A Pending CN106691555A (en) | 2016-12-23 | 2016-12-23 | Template for producing antibiotic-loaded bone cement bead chains |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106691555A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641514A (en) * | 1994-01-29 | 1997-06-24 | Cho; Se Hyun | Cement bead composition for orthopaedic surgery and its manufacturing process |
| CN201684000U (en) * | 2010-04-02 | 2010-12-29 | 王庆贤 | Die for manufacturing bone cement beads |
| CN203506855U (en) * | 2013-09-23 | 2014-04-02 | 张敬东 | Antibiotic bone cement chain bead manufacturing mold |
| CN104207829A (en) * | 2014-09-03 | 2014-12-17 | 吉林大学 | Antibiotic bone cement chain bead manufacturer and method |
| CN206675584U (en) * | 2016-12-23 | 2017-11-28 | 吴迪 | Antibiotic-loaded bone cement chain pearl template |
-
2016
- 2016-12-23 CN CN201611206526.0A patent/CN106691555A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641514A (en) * | 1994-01-29 | 1997-06-24 | Cho; Se Hyun | Cement bead composition for orthopaedic surgery and its manufacturing process |
| CN201684000U (en) * | 2010-04-02 | 2010-12-29 | 王庆贤 | Die for manufacturing bone cement beads |
| CN203506855U (en) * | 2013-09-23 | 2014-04-02 | 张敬东 | Antibiotic bone cement chain bead manufacturing mold |
| CN104207829A (en) * | 2014-09-03 | 2014-12-17 | 吉林大学 | Antibiotic bone cement chain bead manufacturer and method |
| CN206675584U (en) * | 2016-12-23 | 2017-11-28 | 吴迪 | Antibiotic-loaded bone cement chain pearl template |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170524 |
|
| WD01 | Invention patent application deemed withdrawn after publication |