CN106689123A - Microcapsule suspension-suspending agent as well as preparation method and application thereof - Google Patents
Microcapsule suspension-suspending agent as well as preparation method and application thereof Download PDFInfo
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- CN106689123A CN106689123A CN201611026833.0A CN201611026833A CN106689123A CN 106689123 A CN106689123 A CN 106689123A CN 201611026833 A CN201611026833 A CN 201611026833A CN 106689123 A CN106689123 A CN 106689123A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
- A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
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- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Toxicology (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a microcapsule suspension-suspending agent as well as a preparation method and an application thereof. The microcapsule suspension-suspending agent contains an active component and a capsule wall material, wherein the active component comprises pyraclostrobin and hexaconazole, and on the basis of 100 parts by weight of pyraclostrobin, the microcapsule suspension-suspending agent contains 50-150 parts by weight of hexaconazole and 8-20 parts by weight of the capsule wall material. The microcapsule suspension-suspending agent has better storage stability and can be released in a controlled manner to control crop disease in a long term, the number of application times and the dosage are reduced, the cost is saved, and environment pollution is reduced.
Description
Technical field
The present invention relates to pesticide field, in particular it relates to a kind of microcapsule suspension-suspendinagent agent and its preparation method and application.
Background technology
Pyraclostrobin is a kind of wide spectrum, efficient bactericide, can effectively prevent and treat by Ascomycetes, Basidiomycetes, partly know
The crop disease that mushroom and Oomycete fungal cause, and be a kind of plant health care product, be conducive to crop to grow up, strengthen crop pair
The tolerance of ambient influnence, anti-aging, makes blade greener, improves crop yield and quality.Hexaconazole is sterol demethylation
Inhibitor, with interior suction, protection and therapeutic activity, can effectively prevent and treat sac fungus, basidiomycetes and disease caused by Fungi Imperfecti, especially
It is that disease such as powdery mildew, rust, scab, brown spot, the anthracnose etc. caused to Basidiomycetes and Ascomycetes has excellent
Protection and eradicant action.
The problem that the mixing of different type disease occurs is usually present in agricultural production practice, contains single-activity component
Often there is different degrees of defect in bactericide kind, and easily develop immunity to drugs in disease control, expend substantial amounts of people
Power, material resources and financial resources cost, can also cause environmental pollution.Pyraclostrobin and hexaconazole are compounded, wide sterilization spectrum has concurrently
Treatment and protection activity, reduce spraying times, time saving and energy saving, increasing both production and income.Pyraclostrobin fusing point is relatively low, is being prepared into preparation
There is a problem of that bin stability is poor, drug effect is unstable afterwards.
The content of the invention
It is an object of the invention to provide a kind of microcapsule suspension-suspendinagent agent and its preparation method and application, the microcapsule suspension-outstanding
Floating developing agent storage stabilization, can effectively prevent and treat corps diseases, and lasting medicine.
To achieve these goals, first aspect present invention：A kind of microcapsule suspension-suspendinagent agent is provided, the microcapsule suspension-outstanding
Floating agent contains active component and cyst material, and the active component includes pyraclostrobin and hexaconazole, with the institute of 100 weight portions
State on the basis of pyraclostrobin, the content of the hexaconazole is 50-150 weight portions, and the content of the cyst material is 8-20 weights
Amount part.
Preferably, the microcapsule suspension-suspendinagent agent also contains solvent, and the pyraclostrobin with 100 weight portions is base
Standard, the content of the solvent is 80-200 weight portions, and the solvent is selected from petroleum ether, ethyl acetate, dichloromethane, three chloromethanes
At least one in alkane, benzene, dimethylbenzene, solvent naphtha 150 and solvent naphtha 200；The cyst material includes water-soluble cyst wall
Material and oil-soluble cyst material, on the basis of the pyraclostrobin of 100 weight portions, the water-soluble cyst material contains
It is 1-5 weight portions to measure, and the content of the oil-soluble cyst material is 7-14 weight portions；The water-soluble cyst material is selected from second
In diamines, propane diamine, diethylene glycol, diethylenetriamine, triethanolamine and urea resin prepolymer, melamine resin performed polymer extremely
Few one kind, the oil-soluble cyst material is selected from toluene di-isocyanate(TDI), methyl diphenylene diisocyanate, 4,4- diphenyl
Methane diisocyanate, the methylene phenylene diisocyanates of 1,6- six, polymethylene multi-phenenyl isocyanate, aliphatic triisocyanate
With at least one in aliphatic polymeric isocyanate.
Preferably, the microcapsule suspension-suspendinagent agent also contains auxiliary agent, and the pyraclostrobin with 100 weight portions is base
Standard, the content of the auxiliary agent is 60-160 weight portions.
Preferably, the auxiliary agent be selected from dispersion moisture agent, emulsifying agent, thickener, antifreezing agent, preservative, defoamer and
At least one in pH adjusting agent；The dispersion moisture agent is selected from calcium dodecyl benzene sulfonate, sodium methylene bis-naphthalene sulfonate, wood
Quality sodium sulfonate, calcium lignosulfonate, aliphatic alcohol polyoxyvinethene phosphate, AEO, dodecyl sulphate
At least one in sodium and diisobutyl naphthalene；The emulsifying agent be selected from styryl phenol polyethenoxy ether phosphate,
Ben-zylphenol Polyoxyethyl Ether phosphate, anhydrous sorbitol tristearate, the stearate of polyoxyethylene ether alcohol six, poly- second two
Alcohol fatty acid ester, diethylene glycol monolaurate, Brij30, polyoxyethylene monopalmitate and anhydrous sorbitol
At least one in APEO；The thickener is selected from Magnesiumaluminumsilicate, xanthans, polyvinyl alcohol, sodium alginate, melon
At least one in glue, sodium carboxymethylcellulose, organobentonite and white carbon；The antifreezing agent is selected from ethylene glycol, 1,2-
At least one in propane diols, glycerine, urea, polyethylene glycol and sorbierite；The preservative is selected from benzoic acid, benzoic acid
At least one in sodium, sorbic acid and potassium sorbate；The defoamer is selected from polyether antifoam agent, organic silicon defoamer and polyethers
At least one in modified polyorganosiloxane defoamer；The pH adjusting agent is selected from hydrochloric acid, glacial acetic acid, ammonium chloride, ethylenediamine, three
At least one in ethamine, triethanolamine and NaOH.
Preferably, the auxiliary agent is dispersion moisture agent, emulsifying agent, defoamer, antifreezing agent and thickener, with 100 weight portions
The pyraclostrobin on the basis of, the content of the dispersion moisture agent is 30-90 weight portions, and the content of the emulsifying agent is 5-
20 weight portions, the content of the defoamer is 0.5-3 weight portions, and the content of the antifreezing agent is 20-60 weight portions, the thickening
The content of agent is 0.1-6 weight portions.
Second aspect present invention：A kind of method for preparing microcapsule suspension-suspendinagent agent is provided, the method comprises the following steps：
A, by pyraclostrobin, cyst material and water mix, obtain first material, wherein, with the pyraclostrobin of 100 weight portions
On the basis of, the consumption of the cyst material is 8-20 weight portions；B, will hexaconazole and water mix after carry out sanded treatment, obtain the
Two materials, the average grain diameter of the second material is less than 5 microns, wherein, the pyraclostrobin with 100 weight portions is base
Standard, the consumption of the hexaconazole is 50-150 weight portions；The second material that c, the first material that step a is obtained, step b are obtained
With water mixing, microcapsule suspension-suspendinagent agent is obtained.
Preferably, the cyst material includes water-soluble cyst material and oil-soluble cyst material, in step a, first by institute
State pyraclostrobin to mix with solvent and oil-soluble cyst material, obtain the first mixture, first mixture is mixed with water
Close, then carry out shear treatment, obtain the second mixture, then will second mixture mix with water solubility cyst wall material after liter
Temperature, obtains first material；Wherein, on the basis of the pyraclostrobin of 100 weight portions, the consumption of the solvent is 80-200
Weight portion, the consumption of the water-soluble cyst material is 1-5 weight portions, and the consumption of the oil-soluble cyst material is 7-14 weight
Part；The water-soluble cyst material is selected from ethylenediamine, propane diamine, diethylene glycol, diethylenetriamine, triethanolamine and ureaformaldehyde tree
At least one in fat performed polymer, melamine resin performed polymer, the oil-soluble cyst material is selected from toluene di-isocyanate(TDI), two
Methylenebis phenyl isocyanate, 4,4- methyl diphenylene diisocyanates, the methylene phenylene diisocyanates of 1,6- six, polymethylene are more
At least one in phenyl isocyanate, aliphatic triisocyanate and aliphatic polymeric isocyanate；The solvent is selected from stone
In oily ether, ethyl acetate, dichloromethane, chloroform, benzene, dimethylbenzene, solvent naphtha 150 and solvent naphtha 200 at least one
Kind.
Preferably, the method includes：In step a, by the pyraclostrobin and solvent, oil-soluble cyst material and emulsification
Agent mixes, and obtains the first mixture；After dispersion moisture agent and defoamer are mixed with water, then mix so with first mixture
After shear, obtain the second mixture；In step b, by the hexaconazole and water, dispersion moisture agent, defoamer, antifreezing agent and thickening
Sanded treatment is carried out after agent mixing, second material is obtained；And in step c, by the first material, second material He Shui, divide
Wetting agent and antifreezing agent mixing are dissipated, microcapsule suspension-suspendinagent agent is obtained；Wherein, the pyraclostrobin with 100 weight portions is base
Standard, total consumption of the dispersion moisture agent is 30-90 weight portions, and total consumption of the emulsifying agent is 5-20 weight portions, described to disappear
Total consumption of infusion is 0.5-3 weight portions, and total consumption of the antifreezing agent is 20-60 weight portions, total consumption of the thickener
It is 0.1-6 weight portions；The dispersion moisture agent is selected from calcium dodecyl benzene sulfonate, sodium methylene bis-naphthalene sulfonate, sulfomethylated lignin
Sour sodium, calcium lignosulfonate, aliphatic alcohol polyoxyvinethene phosphate, AEO, lauryl sodium sulfate and two
At least one in isobutyl group naphthalene sulfonate；The emulsifying agent is selected from styryl phenol polyethenoxy ether phosphate, benzylphenol
Polyoxyethylene ether phosphate, anhydrous sorbitol tristearate, the stearate of polyoxyethylene ether alcohol six, polyethylene glycol fatty
Acid esters, diethylene glycol monolaurate, Brij30, polyoxyethylene monopalmitate and anhydrous sorbitol polyoxy second
At least one in alkene ether；The thickener is selected from Magnesiumaluminumsilicate, xanthans, polyvinyl alcohol, sodium alginate, guar gum, carboxylic first
At least one in base sodium cellulosate, organobentonite and white carbon；The antifreezing agent be selected from ethylene glycol, 1,2- propane diols,
At least one in glycerine, urea, polyethylene glycol and sorbierite；The defoamer is to disappear selected from polyether antifoam agent, organosilicon
At least one in infusion and Siloxane-Oxyalkylene Copolymers defoamer.
Preferably, the condition of the shear treatment is：Rotating speed is 10000-13000 revs/min, and the time is 1-15 minutes；
The temperature of the intensification is 40-80 DEG C, and the time is 0.5-4 hours.
Third aspect present invention：The microcapsule suspension-suspendinagent agent of offer first aspect present invention is in crop disease is prevented and treated
Using, wherein, the pest and disease damage be selected from powdery mildew, downy mildew, anthracnose, banded sclerotial blight, rice blast and false smut at least
It is a kind of.
By above-mentioned technical proposal, the microcapsule suspension-suspendinagent agent containing pyraclostrobin and hexaconazole of the invention has
Preferable bin stability, can prevent and treat corps diseases slow release long-acting, reduce times for spraying and dosage, cost-effective,
Alleviate the pollution to environment.
Other features and advantages of the present invention will be described in detail in subsequent specific embodiment part.
Specific embodiment
Specific embodiment of the invention is described in detail below.It should be appreciated that described herein specific
Implementation method is merely to illustrate and explain the present invention, and is not intended to limit the invention.
First aspect present invention：A kind of microcapsule suspension-suspendinagent agent is provided, the microcapsule suspension-suspendinagent agent contains active component
And cyst material, the active component include pyraclostrobin and hexaconazole, the pyraclostrobin with 100 weight portions is base
Standard, the content of the hexaconazole is 50-150 weight portions, and the content of the cyst material is 8-20 weight portions.
In the present invention, pyraclostrobin is compound N-[2- [1- (4- chlorphenyls) -1H- pyrazole-3-yl oxygen methyl] benzene
Base] (N- methoxyl groups) methyl carbamate trade name, English name is pyraclostrobin, molecular formula
C19H18ClN3O4, relative molecular mass 387.8, No. CAS：175013-18-0, shown in structural formula such as formula (1).
In the present invention, hexaconazole is compound 2- (2,4- dichlorophenyl) -1- (1H-1,2,4- triazol-1-yls) hex- 2- alcohol
Trade name, English name is hexaconazole, molecular formula C14H17Cl2N3O, relative molecular mass 314.2, No. CAS：
79983-71-4, shown in structural formula such as formula (2).
According to the first aspect of the invention, all tool can have the content of pyraclostrobin and hexaconazole in scope wider
Effect preventing and treating corps diseases, under preferable case, on the basis of the pyraclostrobin of 100 weight portions, the hexaconazole contains
It is 60-120 weight portions to measure, and the content of the cyst material is 10-16 weight portions.
According to the first aspect of the invention, the microcapsule suspension-suspendinagent agent can also contain solvent, with 100 weight portions
On the basis of the pyraclostrobin, the content of the solvent is 80-200 weight portions.The solvent can routinely make for this area
, for example can be selected from petroleum ether, ethyl acetate, dichloromethane, chloroform, benzene, dimethylbenzene, solvent naphtha 150 and
At least one in solvent naphtha 200.
According to the first aspect of the invention, the cyst material can include water-soluble cyst material and oil-soluble cyst wall material
Material.On the basis of the pyraclostrobin of 100 weight portions, the content of the water-soluble cyst material can be 1-5 weight portions,
The content of the oil-soluble cyst material can be 7-14 weight portions.The water-soluble cyst material can be selected from ethylenediamine,
In propane diamine, diethylene glycol, diethylenetriamine, triethanolamine and urea resin prepolymer, melamine resin performed polymer at least one
Kind.The oil-soluble cyst material can be selected from toluene di-isocyanate(TDI), methyl diphenylene diisocyanate, 4,4- diphenyl
Methane diisocyanate, the methylene phenylene diisocyanates of 1,6- six, polymethylene multi-phenenyl isocyanate, aliphatic triisocyanate
With at least one in aliphatic polymeric isocyanate.
According to the first aspect of the invention, the microcapsule suspension-suspendinagent agent also contains auxiliary agent.With described in 100 weight portions
On the basis of pyraclostrobin, the content of the auxiliary agent is 60-160 weight portions.The auxiliary agent can be selected from dispersion moisture agent, breast
At least one in agent, thickener, antifreezing agent, preservative, defoamer and pH adjusting agent.The dispersion moisture agent can be each
Kind can reduce solid or liquid particle in dispersion to assemble and improve the material of wetting action, it is preferable that the dispersion moistening
Agent is selected from calcium dodecyl benzene sulfonate, sodium methylene bis-naphthalene sulfonate, sodium lignin sulfonate, calcium lignosulfonate, poly alkyl alcohol
At least one in oxygen ethene ether phosphate, AEO, lauryl sodium sulfate and diisobutyl naphthalene.
The emulsifying agent can be the various materials with emulsification, it is preferable that the emulsifying agent is selected from styryl phenol polyoxy
Ethene ether phosphate, Ben-zylphenol Polyoxyethyl Ether phosphate, anhydrous sorbitol tristearate, polyoxyethylene ether alcohol six are hard
Resin acid ester, cithrol, diethylene glycol monolaurate, Brij30, polyoxyethylene list palmitic acid
At least one in ester and anhydrous sorbitol APEO.The thickener can be the various viscosity that can improve material
Material, it is preferable that the thickener is selected from Magnesiumaluminumsilicate, xanthans, polyvinyl alcohol, sodium alginate, guar gum, carboxymethyl cellulose
At least one in plain sodium, organobentonite and white carbon.The antifreezing agent can be selected from ethylene glycol, 1,2- propane diols, third
At least one in triol, urea, polyethylene glycol and sorbierite.The preservative can be selected from benzoic acid, Sodium Benzoate, mountain
At least one in pears acid and potassium sorbate；The defoamer is selected from polyether antifoam agent, organic silicon defoamer and polyether-modified
At least one in polysiloxane defoaming agent.The pH adjusting agent can be various acidity or basic species with regulation pH effects
Matter, it is preferable that the pH adjusting agent is selected from hydrochloric acid, glacial acetic acid, ammonium chloride, ethylenediamine, triethylamine, triethanolamine and hydroxide
At least one in sodium.
A kind of specific embodiment according to a first aspect of the present invention, the auxiliary agent is dispersion moisture agent, emulsifying agent, froth breaking
Agent, antifreezing agent and thickener, on the basis of the pyraclostrobin of 100 weight portions, the content of the dispersion moisture agent can be with
It is 30-90 weight portions, the content of the emulsifying agent can be 5-20 weight portions, and the content of the defoamer can be 0.5-3 weights
Amount part, the content of the antifreezing agent can be 20-60 weight portions, and the content of the thickener can be 0.1-6 weight portions.
Second aspect present invention：A kind of method for preparing microcapsule suspension-suspendinagent agent is provided, the method comprises the following steps：
A, by pyraclostrobin, cyst material and water mix, obtain first material, wherein, with the pyraclostrobin of 100 weight portions
On the basis of, the consumption of the cyst material is 8-20 weight portions；B, will hexaconazole and water mix after carry out sanded treatment, obtain the
Two materials, the average grain diameter of the second material is less than 5 microns, wherein, the pyraclostrobin with 100 weight portions is base
Standard, the consumption of the hexaconazole is 50-150 weight portions；The second material that c, the first material that step a is obtained, step b are obtained
With water mixing, microcapsule suspension-suspendinagent agent is obtained.
According to the second aspect of the invention, the cyst material can include water-soluble cyst material and oil-soluble cyst wall material
Material.In step a, first the pyraclostrobin is mixed with solvent and oil-soluble cyst material, obtain the first mixture, will be described
First mixture mixes with water, then carries out shear treatment, obtains the second mixture, then by second mixture with it is water-soluble
Heated up after the mixing of cyst wall material, obtain first material；Wherein, on the basis of the pyraclostrobin of 100 weight portions, the solvent
Consumption be 80-200 weight portions, the consumption of the water-soluble cyst material is 1-5 weight portions, the oil-soluble cyst material
Consumption is 7-14 weight portions.The water-soluble cyst material can be selected from ethylenediamine, propane diamine, diethylene glycol, divinyl three
At least one in amine, triethanolamine and urea resin prepolymer, melamine resin performed polymer.The oil-soluble cyst material can be with
It is selected from toluene di-isocyanate(TDI), methyl diphenylene diisocyanate, 4,4- methyl diphenylene diisocyanates, the methylenes of 1,6- six
In phenylene diisocyanate, polymethylene multi-phenenyl isocyanate, aliphatic triisocyanate and aliphatic polymeric isocyanate extremely
Few one kind.The solvent can be selected from petroleum ether, ethyl acetate, dichloromethane, chloroform, benzene, dimethylbenzene, solvent naphtha
At least one in No. 150 and solvent naphtha 200.
According to the second aspect of the invention, auxiliary agent being added in each step can improve the stabilization of microcapsule suspension-suspendinagent agent
Property.The auxiliary agent can be selected from dispersion moisture agent, emulsifying agent, thickener, antifreezing agent, preservative, defoamer and pH adjusting agent
In at least one.The dispersion moisture agent can reduce solid or liquid particle in dispersion and assemble and improve for various
The material of wetting action, it is preferable that the dispersion moisture agent be selected from calcium dodecyl benzene sulfonate, sodium methylene bis-naphthalene sulfonate,
Sodium lignin sulfonate, calcium lignosulfonate, aliphatic alcohol polyoxyvinethene phosphate, AEO, dodecyl sulphur
At least one in sour sodium and diisobutyl naphthalene.The emulsifying agent can be the various materials with emulsification, excellent
Selection of land, the emulsifying agent is selected from styryl phenol polyethenoxy ether phosphate, Ben-zylphenol Polyoxyethyl Ether phosphate, dehydration mountain
Pears alcohol tristearate, the stearate of polyoxyethylene ether alcohol six, cithrol, diethylene glycol mono laurate
At least one in ester, Brij30, polyoxyethylene monopalmitate and anhydrous sorbitol APEO.It is described
Thickener can be the material of the various viscosity that can improve material, it is preferable that the thickener is selected from Magnesiumaluminumsilicate, xanthan
At least one in glue, polyvinyl alcohol, sodium alginate, guar gum, sodium carboxymethylcellulose, organobentonite and white carbon.It is described
Antifreezing agent can be selected from least one in ethylene glycol, 1,2- propane diols, glycerine, urea, polyethylene glycol and sorbierite.Institute
It can be selected from least one in benzoic acid, Sodium Benzoate, sorbic acid and potassium sorbate to state preservative；The defoamer is choosing
At least one from polyether antifoam agent, organic silicon defoamer and Siloxane-Oxyalkylene Copolymers defoamer.The pH adjusting agent can
Think it is various with regulation pH effect acidity or alkaline matters, it is preferable that the pH adjusting agent be selected from hydrochloric acid, glacial acetic acid,
At least one in ammonium chloride, ethylenediamine, triethylamine, triethanolamine and NaOH.
For example, in step a, the pyraclostrobin can be mixed with solvent, oil-soluble cyst material and emulsifying agent, obtain
To the first mixture, after then mixing dispersion moisture agent and defoamer with water, then mix with first mixture and then cut
Cut, obtain the second mixture.In step b, can be by the hexaconazole and water, dispersion moisture agent, defoamer, antifreezing agent and thickening
Sanded treatment is carried out after agent mixing, second material is obtained.In step c, can by the first material, second material He Shui, point
Wetting agent and antifreezing agent mixing are dissipated, microcapsule suspension-suspendinagent agent is obtained.Wherein, the pyraclostrobin with 100 weight portions is base
Standard, total consumption of the dispersion moisture agent can be 30-90 weight portions, and total consumption of the emulsifying agent can be 5-20 weight
Part, total consumption of the defoamer can be 0.5-3 weight portions, and total consumption of the antifreezing agent can be 20-60 weight portions, institute
The total consumption for stating thickener can be 0.1-6 weight portions.
According to the second aspect of the invention, the shear treatment is well known to those skilled in the art, it is preferable that described to cut
The condition for cutting treatment is：Rotating speed is 10000-13000 revs/min, and the time is 1-15 minutes.The temperature of the intensification can be
40-80 DEG C, the time is 0.5-4 hours.
Third aspect present invention：The microcapsule suspension-suspendinagent agent of offer first aspect present invention is in crop disease is prevented and treated
Using, wherein, the pest and disease damage be selected from powdery mildew, downy mildew, anthracnose, banded sclerotial blight, rice blast and false smut at least
It is a kind of.
The present invention is further described by the following examples, is not intended to limit the invention.
Pyraclostrobin is purchased from Limin Chemical Co., Ltd.；Hexaconazole is limited purchased from Jiangsu Qi Zhou green chemical industry shares
Company；Solvent naphtha 150, solvent naphtha 200 are purchased from Hualun Chemical Co., Ltd., Jiangsu；Aliphatic polymeric isocyanate is purchased from Guangzhou
Hao Yi Chemical Industry Science Co., Ltd；Toluene di-isocyanate(TDI) is purchased from Jinan great Hui Chemical Industry Science Co., Ltd；The many benzene of polymethylene
Based isocyanate is purchased from Jinan Lin Sheng Chemical Co., Ltd.s；Anhydrous sorbitol APEO, Ben-zylphenol Polyoxyethyl Ether phosphoric acid
Ester, Brij30, AEO are purchased from Xingtai blue star auxiliary reagent factory；Sodium lignin sulfonate, sulfomethylated lignin
Sour calcium is purchased from Shandong Lv Cheng Chemical Co., Ltd.s；Diisobutyl sodium naphthalene sulfonate is purchased from Jinan element Chemical Co., Ltd.；Organosilicon
Defoamer, polyether antifoam agent are purchased from middle federal defoamer factory；Ethylenediamine, lauryl sodium sulfate, ethylene glycol, Sodium Benzoate, ice
Acetic acid, glycerine, ethyl acetate, diethylene glycol, propane diols, NaOH are purchased from the magnificent Zhi Bo Science and Technology Ltd.s in Beijing；It is yellow
Virgin rubber is purchased from Zibo Deosen Biochemical Ltd.；Sodium methylene bis-naphthalene sulfonate is purchased from Jinan City Licheng District Gaosheng chemical industry；Magnesium silicate
Aluminium is purchased from Hunan Peng Tai new high-tech materials Co., Ltd.
Embodiment 1
The present embodiment is used to illustrate the preparation (pyrazoles of 20 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agents
Kresoxim-methyl 10 weight %, the weight % of hexaconazole 10).
20.6 grams of pyraclostrobins (content 98%) are dissolved in 30 grams of solvent naphthas 150,2 grams of aliphatic poly isocyanides are added
Acid esters and 3 grams of anhydrous sorbitol APEOs, stir, and obtain the first mixture；By 3 grams of sodium lignin sulfonates, 0.2 gram
After organic silicon defoamer mixes with 40.7 grams of water, then mix with the first mixture, then in 10000 revs/min of condition down cuts 1
Minute, obtain the second mixture；To 0.5 gram of ethylenediamine is added dropwise in the second mixture, 50 DEG C of insulation reactions are warming up to 2 hours, obtain
To 100 grams of first materials containing 20 weight % pyraclostrobins.
By 26.5 grams of hexaconazole active compounds (content 95%), 2 grams of lauryl sodium sulfate, 6 grams of sodium lignin sulfonates, 0.2 gram
Organic silicon defoamer, 5 grams of ethylene glycol, 0.3 gram of xanthans, 0.2 gram of Sodium Benzoate are sufficiently mixed with 59.8 grams of water, disperse, dispersion
Sand mill is passed through after uniform to be sanded, the suspension less than 5 microns is sanded to average grain diameter, that is, obtain 100 grams and contain 25 weights
Measure the second material of % hexaconazoles.
By 50 grams of first material, 40 grams of second material, 3 grams of ethylene glycol, 2 grams of sodium methylene bis-naphthalene sulfonates, 1 gram of ice vinegar
Acid and 4 grams of water are sufficiently mixed, and dispersed with stirring is uniform, that is, obtain 100 gram of 20 weight % pyraclostrobin hexaconazoles microcapsule suspension-
Suspending agent (pyraclostrobin 10 weight %, the weight % of hexaconazole 10).
Embodiment 2
The present embodiment is used to illustrate the preparation (pyrazoles of 20 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agents
Kresoxim-methyl 10 weight %, the weight % of hexaconazole 10).
20.6 grams of pyraclostrobins (content 98%) are dissolved in 35 grams of solvent naphthas 150, add 2.5 grams of aliphatic polies different
Cyanate and 3 grams of anhydrous sorbitol APEOs, stir, and obtain the first mixture；By 3 grams of sodium lignin sulfonates, 0.2
After gram organic silicon defoamer mixes with 35.2 grams of water, then mix with the first mixture, then cut under the conditions of 12000 revs/min
Cut 1 minute, obtain the second mixture；To 0.5 gram of ethylenediamine is added dropwise in the second mixture, 50 DEG C of insulation reactions 2.5 are warming up to small
When, obtain 100 grams of first materials containing 20 weight % pyraclostrobins.
The preparation method of second material is with embodiment 1.
By 50 grams of first material, 40 grams of second material, 3 grams of ethylene glycol, 2 grams of sodium methylene bis-naphthalene sulfonates, 0.5 gram of ice
Acetic acid and 4.5 grams of water are sufficiently mixed, and dispersed with stirring is uniform, that is, obtain 100 gram of 20 weight % pyraclostrobin hexaconazole micro-capsule
Suspension-suspending agent (pyraclostrobin 10 weight %, the weight % of hexaconazole 10).
Embodiment 3
The present embodiment is used to illustrate the preparation (pyrazoles of 20 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agents
Kresoxim-methyl 10 weight %, the weight % of hexaconazole 10).
20.6 grams of pyraclostrobins (content 98%) are dissolved in 30 grams of solvent naphthas 150,2 grams of aliphatic poly isocyanides are added
Acid esters and 3.5 grams of anhydrous sorbitol APEOs, stir, and obtain the first mixture；By 3 grams of sodium lignin sulfonates, 0.2
After gram organic silicon defoamer and 40.4 grams of water mixing, then mix with the first mixture, then cut under the conditions of 10000 revs/min
Cut 1 minute, obtain the second mixture；To 0.3 gram of ethylenediamine is added dropwise in the second mixture, 60 DEG C of insulation reactions 1.5 are warming up to small
When, that is, obtain 100 grams of first materials containing 20 weight % pyraclostrobins.
The preparation method of second material is with embodiment 1.
By 50 grams of first material, 40 grams of second material, 3 grams of ethylene glycol, 2 grams of sodium methylene bis-naphthalene sulfonates and 5 grams of water
It is sufficiently mixed, dispersed with stirring is uniform, that is, obtain 100 gram of 20 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agent (pyrrole
Azoles kresoxim-methyl 10 weight %, the weight % of hexaconazole 10).
Embodiment 4
The present embodiment is used to illustrate the preparation (pyrazoles of 20 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agents
Kresoxim-methyl 10 weight %, the weight % of hexaconazole 10).
20.6 grams of pyraclostrobins (content 98%) are dissolved in 35 grams of solvent naphthas 200,2.1 grams of toluene diisocyanates are added
Acid esters and 3 grams of Ben-zylphenol Polyoxyethyl Ether phosphates, stir, and obtain the first mixture；By 3 grams of di-2-ethylhexylphosphine oxide naphthalene sulfonic acids
After sodium, 0.2 gram of polyether antifoam agent and 35.4 grams of water mixing, then mix with the first mixture, then in 12000 revs/min of conditions
Down cut 1 minute, obtains the second mixture；To 0.7 gram of diethylenetriamine is added dropwise in the second mixture, 50 DEG C of insulations are warming up to anti-
Answer 2.5 hours, that is, obtain 100 grams of first materials containing 20 weight % pyraclostrobins.
By 26.5 grams of hexaconazole active compounds (content 95%), 2 grams of lauryl sodium sulfate, 6 grams of sodium methylene bis-naphthalene sulfonates,
0.2 gram of polyether antifoam agent, 5 grams of glycerine, 1 gram of aluminium-magnesium silicate are sufficiently mixed with 59.3 grams of water, disperse, and sand is passed through after being uniformly dispersed
Grinding machine is sanded, and the suspension less than 5 microns is sanded to average grain diameter, that is, obtain 100 grams and contain 25 weight % hexaconazoles
Second material.
By 50 grams of first material, 40 grams of second material, 3 grams of ethylene glycol, 2 grams of sodium methylene bis-naphthalene sulfonates, 0.5 gram of ice
Acetic acid and 4.5 grams of water are sufficiently mixed, and dispersed with stirring is uniform, that is, obtain 100 gram of 20 weight % pyraclostrobin hexaconazole micro-capsule
Suspension-suspending agent (pyraclostrobin 10 weight %, the weight % of hexaconazole 10).
Embodiment 5
The present embodiment is used to illustrate the preparation (pyrazoles of 20 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agents
Kresoxim-methyl 10 weight %, the weight % of hexaconazole 10).
20.6 grams of pyraclostrobins (content 98%) are dissolved in 35 grams of ethyl acetate, 2.5 grams of many benzene of polymethylene are added
Based isocyanate and 3 grams of Brij30s, stir, and obtain the first mixture；By 3 grams of calcium lignosulfonates, 0.2
After gram organic silicon defoamer mixes with 35.4 grams of water, then mix with the first mixture, then cut under the conditions of 10000 revs/min
Cut 1 minute, obtain the second mixture；To 0.3 gram of diethylene glycol is added dropwise in the second mixture, 60 DEG C of insulation reactions 3 are warming up to small
When, that is, obtain 100 grams of first materials containing 20 weight % pyraclostrobins.
By 26.5 grams of hexaconazole active compounds (content 95%), 2 grams of diisobutyl naphthalenes, 5 grams of AEOs,
0.2 gram of organic silicon defoamer, 5 grams of propane diols, 0.5 gram of polyvinyl alcohol are sufficiently mixed with 60.8 grams of water, disperse, and lead to after being uniformly dispersed
Enter sand mill to be sanded, the suspension less than 5 microns is sanded to average grain diameter, that is, obtain 100 grams and contain the 25 own azoles of weight %
The second material of alcohol.
By 50 grams of first material, 40 grams of second material, 3 grams of propane diols, 2 grams of calcium lignosulfonates, 0.2 gram of hydroxide
Sodium and 4.8 grams of water are sufficiently mixed, and dispersed with stirring is uniform, that is, obtain 100 gram of 20 weight % pyraclostrobin hexaconazoles micro-capsule and hang
Floating-suspending agent (pyraclostrobin 10 weight %, the weight % of hexaconazole 10).
Embodiment 6
The present embodiment is used to illustrate the preparation (pyrazoles of 12 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agents
Kresoxim-methyl 7 weight %, the weight % of hexaconazole 5).
14.4 grams of pyraclostrobins (content 98%) are dissolved in 25 grams of solvent naphthas 150, add 1.5 grams of aliphatic polies different
Cyanate and 2 grams of anhydrous sorbitol APEOs, stir, and obtain the first mixture；By 2.5 grams of sodium lignin sulfonates,
After 0.2 gram of organic silicon defoamer mixes with 54 grams of water, then mix with the first mixture, then cut under the conditions of 12000 revs/min
Cut 1 minute, obtain the second mixture；To 0.4 gram of ethylenediamine is added dropwise in the second mixture, 50 DEG C of insulation reactions 2.5 are warming up to small
When, that is, obtain 100 grams of first materials containing 14 weight % pyraclostrobins.
By 13.2 grams of hexaconazole active compounds (content 95%), 2 grams of lauryl sodium sulfate, 5 grams of sodium lignin sulfonates, 0.2 gram
Organic silicon defoamer, 5 grams of ethylene glycol, 0.3 gram of xanthans, 0.2 gram of Sodium Benzoate are sufficiently mixed with 74.1 grams of water, disperse, dispersion
Sand mill is passed through after uniform to be sanded, the suspension less than 5 microns is sanded to average grain diameter, that is, obtain 100 grams and contain
The second material of 12.5% weight % hexaconazoles.
By 50 grams of first material, 40 grams of second material, 3 grams of ethylene glycol, 2 grams of sodium methylene bis-naphthalene sulfonates, 0.5 gram of ice
Acetic acid and 4.5 grams of water are sufficiently mixed, and dispersed with stirring is uniform, that is, obtain 100 gram of 12 weight % pyraclostrobin hexaconazole micro-capsule
Suspension-suspending agent (pyraclostrobin 7 weight %, the weight % of hexaconazole 5).
Embodiment 7
The present embodiment is used to illustrate the preparation (pyrazoles of 35 weight % pyraclostrobin hexaconazole microcapsule suspension-suspendinagent agents
Kresoxim-methyl 15 weight %, the weight % of hexaconazole 20).
33.8 grams of pyraclostrobins (content 98%) are dissolved in 35 grams of solvent naphthas 150,3 grams of aliphatic poly isocyanides are added
Acid esters and 2 grams of anhydrous sorbitol APEOs, stir, and obtain the first mixture；By 2.5 grams of sodium lignin sulfonates, 0.2
After gram organic silicon defoamer mixes with 23 grams of water, then mix with the first mixture, then in 12000 revs/min of condition down cuts 1
Minute, obtain the second mixture；To 0.5 gram of ethylenediamine is added dropwise in the second mixture, 50 DEG C of insulation reactions are warming up to 2.5 hours,
Obtain 100 grams of first materials containing 33 weight % pyraclostrobins.
By 47.5 grams of hexaconazole active compounds (content 95%), 2 grams of lauryl sodium sulfate, 6 grams of sodium lignin sulfonates, 0.2 gram
Organic silicon defoamer, 5 grams of ethylene glycol, 0.1 gram of xanthans, 0.1 gram of Sodium Benzoate are sufficiently mixed with 39.1 grams of water, disperse, dispersion
Sand mill is passed through after uniform to be sanded, the suspension less than 5 microns is sanded to average grain diameter, that is, obtain 100 grams and contain 45%
The second material of weight % hexaconazoles.
By 45.5 grams of first material, 44.5 grams of second material, 3 grams of ethylene glycol, 2 grams of sodium methylene bis-naphthalene sulfonates, 0.2
Gram glacial acetic acid and 4.8 grams of water are sufficiently mixed, and dispersed with stirring is uniform, that is, obtain 100 gram of 35 weight % pyraclostrobin hexaconazole
Microcapsule suspension-suspendinagent agent (pyraclostrobin 15 weight %, the weight % of hexaconazole 20).
Comparative example 1
This comparative example is used to illustrate the preparation (weight of pyraclostrobin 10 of 20 weight % pyraclostrobin hexaconazole suspending agents
Amount %, the weight % of hexaconazole 10).
By 10.4 grams of pyraclostrobin active compounds (content 98%), 10.7 grams of hexaconazole active compounds (content 95%), 2 grams of dodecanes
Base sodium sulphate, 6 grams of sodium lignin sulfonates, 0.2 gram of organic silicon defoamer, 5 grams of ethylene glycol, 0.3 gram of xanthans, 0.2 gram of benzoic acid
Sodium is sufficiently mixed with 65.2 grams of water, disperses, and being passed through sand mill after being uniformly dispersed is sanded, and is sanded micro- less than 5 to average grain diameter
The suspension of rice, that is, obtain 100 gram of 20 weight % pyraclostrobin hexaconazole suspending agent.
Comparative example 2
This comparative example is used to illustrate the preparation (pyraclostrobin of 20 weight % pyraclostrobin hexaconazole wettable powders
10 weight %, the weight % of hexaconazole 10).
By 10.4 grams of pyraclostrobin active compounds (content 98%), 10.7 grams of hexaconazole active compounds (content 95%), 2 grams of dodecanes
Base sodium sulphate, 6 grams of sodium lignin sulfonates and 70.9 grams of kaolin are sufficiently mixed, and 100 gram of 20 weight % pyrazoles ether is obtained after crushing
Bacterium ester hexaconazole wettable powder.
Comparative example 3
This comparative example is used to illustrate the preparation (pyraclostrobin of 20 weight % pyraclostrobin diniconazole water dispersible granules
10 weight %, the weight % of hexaconazole 10).
By 10.4 grams of pyraclostrobin active compounds (content 98%), 10.7 grams of hexaconazole active compounds (content 95%), 2 grams of dodecanes
Base sodium sulphate, 6 grams of sodium lignin sulfonates and 70.9 grams of kaolin are sufficiently mixed, and size-reduced, extruder grain obtains 100 gram of 20 weight
Amount % pyraclostrobin diniconazole water dispersible granules.
Comparative example 4
This comparative example is used to illustrate the preparation (weight of pyraclostrobin 10 of 20 weight % pyraclostrobin hexaconazole missible oil
Amount %, the weight % of hexaconazole 10).
10.4 grams of pyraclostrobin active compounds (content 98%), 10.7 grams of hexaconazole active compounds (content 95%) are dissolved in 63.9
In gram solvent naphtha 150,5 grams of calcium dodecyl benzene sulfonates, 10 grams of styryl phenol polyethenoxy ether phosphates are added, mixing,
It is uniformly dispersed, that is, obtains 100 gram of 20 weight % pyraclostrobin hexaconazole missible oil.
Testing example 1
This testing example is used for the heat storage stability and low-temperature stabilization of the sample of testing example 1-7 and comparative example 1-4
Property.
Heat storage stability is tested：The sample of embodiment 1-7 and comparative example 1-4 is fitted into container, (54 are positioned over after sealing
2) DEG C stored 14 days in ± constant temperature oven, then take out and be placed in after room temperature condition recovers, tested as follows：Embodiment 1-7
Sample with comparative example 1-3 carries out the measure of suspensibility according to GB/T 14825-2006；The sample of comparative example 4 is according to GB/T1603-
2001 measure for carrying out stability of emulsion.The results are shown in Table 1.
Low-temperature stability is determined：The sample of embodiment 1-7 and comparative example 1-4 is fitted into container, be placed in after sealing (0 ±
2) in DEG C refrigerator, kept for 1 hour, at interval of stirring in 15 minutes once, 15 seconds every time, observation outward appearance had unchanged, (0 ±
2) a DEG C continuation is placed 7 days, is then taken out after being placed in room temperature condition recovery, is tested as follows：Embodiment 1-7 and comparative example 1-3
Sample the measure of suspensibility is carried out according to GB/T14825-2006；The sample of comparative example 4 carries out emulsion according to GB/T1603-2001
The measure of stability.The results are shown in Table 1.
Table 1
As it can be seen from table 1 the micro-capsule of the pyraclostrobin-containing that obtains of preparation method that provides of the present invention and hexaconazole hangs
Floating-suspending agent has good heat storage stability and low-temperature stability compared with other formulations.
Testing example 2
This testing example is to the sample of embodiment 1-7 and comparative example 1-4 to rice sheath blight disease, rice blast and false smut
Prevention effect is tested.
Test site：Jiangxi Province Taihe County Jiang Bin villages, in soil fertility on, the growing area area for testing each sample is
1 mu, rice varieties are advisable fragrant No. 10, each treatment region paddy rice routinely production management after plantation.
The sample of testing example 1-7 and comparative example 1-4 is to banded sclerotial blight, rice blast and false smut in Rice Cropping field
Prevention effect, specific steps include：It it is 60kg/ mus according to spouting liquid, by embodiment 1-7 and contrast using knapsack sprayer
The sample of example 1-4 is uniformly sprayed on the paddy rice complete stool of each growing area respectively, and blank control group is using clear water to growing area
Complete stool is sprayed paddy rice.Every kind of sample is used after being watered dilution by following mu consumption：
Embodiment 1-5 and comparative example 1-4：35 grams/acre；
Embodiment 6：60 grams/acre；
Embodiment 7：20 grams/acre.
After dispenser 10 days, 20 days, 30 days and 50 days, according to《The pesticide field efficacy medicine test criterions of GB/T 17980》To plantation
The state of an illness of the banded sclerotial blight, rice blast and false smut of area paddy rice is investigated and counted, and disease index is calculated according to formula (I), according to
Formula (II) calculates prevention effect, as a result as shown in table 2.
Table 2
Testing example 3
This testing example is to the sample of embodiment 1-7 and comparative example 1-4 to cucumber plant powdery mildew, downy mildew and anthrax
The prevention effect of disease is tested.
Test site：Peace town Dong Sheng villages of Shandong Province, in soil fertility on, the growing area area for testing each sample is
1 mu, cucumber variety is Shandong cucumber No. three.
In green cucumber area the sample of testing example 1-7 and comparative example 1-4 to cucumber plant powdery mildew, downy mildew and
The prevention effect of anthracnose, specific steps include：It it is 30kg/ mus according to spouting liquid, by embodiment 1- using knapsack sprayer
The sample of 7 and comparative example 1-4 is uniformly sprayed on the cucumber plant blade tow sides and its fruit of each growing area respectively, empty
White control group is sprayed using clear water to the cucumber plant of growing area.Every kind of sample makes after being watered dilution by following mu consumption
With：
Embodiment 1-5 and comparative example 1-4：30 grams/acre；
Embodiment 6：50 grams/acre；
Embodiment 7：20 grams/acre.
After dispenser 10 days, 20 days, 30 days and 50 days, according to《The pesticide field efficacy medicine test criterions of GB/T 17980》To plantation
The state of an illness of area cucumber plant powdery mildew, downy mildew and anthracnose is investigated and counted, and disease index, root are calculated according to formula (I)
Prevention effect is calculated according to formula (II), as a result as shown in table 3.
Table 3
From table 2 and table 3 as can be seen that the pyraclostrobin-containing that provides of the present invention and hexaconazole microcapsule suspension-suspendinagent agent
The prevention effect of preparation method, the pyraclostrobin-containing for preparing and hexaconazole microcapsule suspension-suspendinagent agent is substantially better than containing pyrrole
Other formulations of azoles kresoxim-methyl and hexaconazole, and still keep preventive effect higher in 30 days and 50 days after spray, it is seen that it is of the invention
The lasting effect of the microcapsule suspension-suspendinagent agent of pyraclostrobin-containing and hexaconazole is good, can prevent and treat corps diseases slow release long-acting,
Times for spraying and dosage are reduced, it is cost-effective, alleviate the pollution to environment.
The preferred embodiment of the present invention described in detail above, but, the present invention is not limited in above-mentioned implementation method
Detail, in range of the technology design of the invention, various simple variants can be carried out to technical scheme, this
A little simple variants belong to protection scope of the present invention.
It is further to note that each particular technique feature described in above-mentioned specific embodiment, in not lance
In the case of shield, can be combined by any suitable means, in order to avoid unnecessary repetition, the present invention to it is various can
The combination of energy is no longer separately illustrated.
Additionally, can also be combined between a variety of implementation methods of the invention, as long as it is without prejudice to originally
The thought of invention, it should equally be considered as content disclosed in this invention.
Claims (10)
1. a kind of microcapsule suspension-suspendinagent agent, it is characterised in that the microcapsule suspension-suspendinagent agent contains active component and cyst material,
The active component includes pyraclostrobin and hexaconazole, on the basis of the pyraclostrobin of 100 weight portions, the own azoles
The content of alcohol is 50-150 weight portions, and the content of the cyst material is 8-20 weight portions.
2. microcapsule suspension-suspendinagent agent according to claim 1, wherein, the microcapsule suspension-suspendinagent agent also contains solvent,
On the basis of the pyraclostrobin of 100 weight portions, the content of the solvent is 80-200 weight portions, the solvent be selected from
In petroleum ether, ethyl acetate, dichloromethane, chloroform, benzene, dimethylbenzene, solvent naphtha 150 and solvent naphtha 200 at least
It is a kind of；
The cyst material includes water-soluble cyst material and oil-soluble cyst material, with the pyrazoles ether bacterium of 100 weight portions
On the basis of ester, the content of the water-soluble cyst material is 1-5 weight portions, and the content of the oil-soluble cyst material is 7-14 weights
Amount part；The water-soluble cyst material is selected from ethylenediamine, propane diamine, diethylene glycol, diethylenetriamine, triethanolamine and ureaformaldehyde
At least one in resin prepolymer, melamine resin performed polymer, the oil-soluble cyst material be selected from toluene di-isocyanate(TDI),
Methyl diphenylene diisocyanate, 4,4- methyl diphenylene diisocyanates, the methylene phenylene diisocyanates of 1,6- six, polymethylene
At least one in many phenyl isocyanates, aliphatic triisocyanate and aliphatic polymeric isocyanate.
3. microcapsule suspension-suspendinagent agent according to claim 1 and 2, wherein, the microcapsule suspension-suspendinagent agent is also containing helping
Agent, on the basis of the pyraclostrobin of 100 weight portions, the content of the auxiliary agent is 60-160 weight portions.
4. microcapsule suspension-suspendinagent agent according to claim 3, wherein, the auxiliary agent is selected from dispersion moisture agent, emulsification
At least one in agent, thickener, antifreezing agent, preservative, defoamer and pH adjusting agent；The dispersion moisture agent is selected from 12
Alkyl benzene calcium sulfonate, sodium methylene bis-naphthalene sulfonate, sodium lignin sulfonate, calcium lignosulfonate, AEO phosphoric acid
At least one in ester, AEO, lauryl sodium sulfate and diisobutyl naphthalene；The emulsifying agent is
Selected from styryl phenol polyethenoxy ether phosphate, Ben-zylphenol Polyoxyethyl Ether phosphate, anhydrous sorbitol tristearate, poly-
The stearate of oxygen ethene sorb ether alcohol six, cithrol, diethylene glycol monolaurate, polyoxyethylene lauryl alcohol
At least one in ether, polyoxyethylene monopalmitate and anhydrous sorbitol APEO；The thickener is selected from silicic acid
In magnalium, xanthans, polyvinyl alcohol, sodium alginate, guar gum, sodium carboxymethylcellulose, organobentonite and white carbon at least
It is a kind of；The antifreezing agent is selected from least in ethylene glycol, 1,2- propane diols, glycerine, urea, polyethylene glycol and sorbierite
Kind；The preservative is selected from least one in benzoic acid, Sodium Benzoate, sorbic acid and potassium sorbate；The defoamer is
Selected from least one in polyether antifoam agent, organic silicon defoamer and Siloxane-Oxyalkylene Copolymers defoamer；The pH adjusting agent
It is selected from least one in hydrochloric acid, glacial acetic acid, ammonium chloride, ethylenediamine, triethylamine, triethanolamine and NaOH.
5. microcapsule suspension-suspendinagent agent according to claim 4, wherein, the auxiliary agent is dispersion moisture agent, emulsifying agent, disappears
Infusion, antifreezing agent and thickener, on the basis of the pyraclostrobin of 100 weight portions, the content of the dispersion moisture agent is
30-90 weight portions, the content of the emulsifying agent is 5-20 weight portions, and the content of the defoamer is 0.5-3 weight portions, described anti-
The content for freezing agent is 20-60 weight portions, and the content of the thickener is 0.1-6 weight portions.
6. a kind of method for preparing microcapsule suspension-suspendinagent agent, it is characterised in that the method comprises the following steps：
A, by pyraclostrobin, cyst material and water mix, obtain first material, wherein, with the pyrazoles ether of 100 weight portions
On the basis of bacterium ester, the consumption of the cyst material is 8-20 weight portions；
B, will hexaconazole and water mix after carry out sanded treatment, obtain second material, the average grain diameter of the second material is less than 5
Micron, wherein, on the basis of the pyraclostrobin of 100 weight portions, the consumption of the hexaconazole is 50-150 weight portions；
Second material and water mixing that c, the first material that step a is obtained, step b are obtained, obtain microcapsule suspension-suspendinagent agent.
7. method according to claim 6, wherein, the cyst material includes water-soluble cyst material and oil-soluble cyst wall
Material, in step a, first mixes the pyraclostrobin with solvent and oil-soluble cyst material, obtains the first mixture, by institute
State the first mixture to mix with water, then carry out shear treatment, obtain the second mixture, then by second mixture with it is water-soluble
Property the mixing of cyst wall material after heat up, obtain first material；Wherein, it is described molten on the basis of the pyraclostrobin of 100 weight portions
The consumption of agent is 80-200 weight portions, and the consumption of the water-soluble cyst material is 1-5 weight portions, the oil-soluble cyst material
Consumption be 7-14 weight portions；The water-soluble cyst material be selected from ethylenediamine, propane diamine, diethylene glycol, diethylenetriamine,
At least one in triethanolamine and urea resin prepolymer, melamine resin performed polymer, the oil-soluble cyst material be selected from
Toluene di-isocyanate(TDI), methyl diphenylene diisocyanate, 4,4- methyl diphenylene diisocyanates, the methylene benzene two of 1,6- six are different
At least one in cyanate, polymethylene multi-phenenyl isocyanate, aliphatic triisocyanate and aliphatic polymeric isocyanate；
The solvent is selected from petroleum ether, ethyl acetate, dichloromethane, chloroform, benzene, dimethylbenzene, solvent naphtha 150 and solvent naphtha
At least one in No. 200.
8. method according to claim 7, wherein, the method includes：In step a, by the pyraclostrobin and solvent,
Oil-soluble cyst material and emulsifying agent mix, and obtain the first mixture；
After dispersion moisture agent and defoamer are mixed with water, then mix with first mixture and then shearing, obtain second and mix
Compound；
In step b, carried out at sand milling after the hexaconazole and water, dispersion moisture agent, defoamer, antifreezing agent and thickener are mixed
Reason, obtains second material；And
In step c, by the first material, second material and water, dispersion moisture agent and antifreezing agent mix, obtain microcapsule suspension-
Suspending agent；
Wherein, on the basis of the pyraclostrobin of 100 weight portions, total consumption of the dispersion moisture agent is 30-90 weight
Part, total consumption of the emulsifying agent is 5-20 weight portions, and total consumption of the defoamer is 0.5-3 weight portions, the antifreezing agent
Total consumption be 20-60 weight portions, total consumption of the thickener is 0.1-6 weight portions；
The dispersion moisture agent is selected from calcium dodecyl benzene sulfonate, sodium methylene bis-naphthalene sulfonate, sodium lignin sulfonate, lignin
Sulfoacid calcium, aliphatic alcohol polyoxyvinethene phosphate, AEO, lauryl sodium sulfate and diisobutyl naphthalene sulfonic acids
At least one in salt；The emulsifying agent is selected from styryl phenol polyethenoxy ether phosphate, Ben-zylphenol Polyoxyethyl Ether phosphorus
Acid esters, anhydrous sorbitol tristearate, the stearate of polyoxyethylene ether alcohol six, cithrol, diethyl two
In alcohol monolaurate, Brij30, polyoxyethylene monopalmitate and anhydrous sorbitol APEO extremely
Few one kind；The thickener be selected from Magnesiumaluminumsilicate, xanthans, polyvinyl alcohol, sodium alginate, guar gum, sodium carboxymethylcellulose,
At least one in organobentonite and white carbon；The antifreezing agent be selected from ethylene glycol, 1,2- propane diols, glycerine, urea,
At least one in polyethylene glycol and sorbierite；The defoamer is to change selected from polyether antifoam agent, organic silicon defoamer and polyethers
At least one in property polysiloxane defoaming agent.
9. method according to claim 7, wherein, the condition of the shear treatment is：Rotating speed be 10000-13000 turn/
Minute, the time is 1-15 minutes；The temperature of the intensification is 40-80 DEG C, and the time is 0.5-4 hours.
10. application of the microcapsule suspension-suspendinagent agent in claim 1-5 described in any one in crop disease is prevented and treated, wherein,
The disease is selected from least one in powdery mildew, downy mildew, anthracnose, banded sclerotial blight, rice blast and false smut.
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| CN201611026833.0A CN106689123A (en) | 2016-11-15 | 2016-11-15 | Microcapsule suspension-suspending agent as well as preparation method and application thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107279150A (en) * | 2017-05-26 | 2017-10-24 | 北京明德立达农业科技有限公司 | A kind of microcapsule suspension suspending agent of containing chlorantraniliprole and AVM and preparation method thereof |
| CN107593722A (en) * | 2017-09-22 | 2018-01-19 | 河北中天邦正生物科技股份公司 | A kind of microcapsule suspension suspending agent containing benziothiazolinone and pyraclostrobin and preparation method thereof |
| CN107853310A (en) * | 2017-10-30 | 2018-03-30 | 北京明德立达农业科技有限公司 | A kind of pyraclostrobin-containing and the microcapsule suspension suspending agent of fluxapyroxad and preparation method thereof |
| CN108378027A (en) * | 2018-03-20 | 2018-08-10 | 南京高正农用化工有限公司 | A kind of microcapsule suspension-suspendinagent agent containing Pendimethalin and flumioxazin |
| CN109221208A (en) * | 2018-09-18 | 2019-01-18 | 深圳诺普信农化股份有限公司 | A kind of water dispersible granules and preparation method thereof containing pyraclostrobin |
| CN114698635A (en) * | 2022-04-19 | 2022-07-05 | 安徽农业大学 | Pyraclostrobin microcapsule based on sodium alginate and preparation method thereof |
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| CN107279150A (en) * | 2017-05-26 | 2017-10-24 | 北京明德立达农业科技有限公司 | A kind of microcapsule suspension suspending agent of containing chlorantraniliprole and AVM and preparation method thereof |
| CN107593722A (en) * | 2017-09-22 | 2018-01-19 | 河北中天邦正生物科技股份公司 | A kind of microcapsule suspension suspending agent containing benziothiazolinone and pyraclostrobin and preparation method thereof |
| CN107853310A (en) * | 2017-10-30 | 2018-03-30 | 北京明德立达农业科技有限公司 | A kind of pyraclostrobin-containing and the microcapsule suspension suspending agent of fluxapyroxad and preparation method thereof |
| CN108378027A (en) * | 2018-03-20 | 2018-08-10 | 南京高正农用化工有限公司 | A kind of microcapsule suspension-suspendinagent agent containing Pendimethalin and flumioxazin |
| CN109221208A (en) * | 2018-09-18 | 2019-01-18 | 深圳诺普信农化股份有限公司 | A kind of water dispersible granules and preparation method thereof containing pyraclostrobin |
| CN114698635A (en) * | 2022-04-19 | 2022-07-05 | 安徽农业大学 | Pyraclostrobin microcapsule based on sodium alginate and preparation method thereof |
| CN114698635B (en) * | 2022-04-19 | 2022-12-13 | 安徽农业大学 | Pyraclostrobin microcapsule based on sodium alginate and preparation method thereof |
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Application publication date: 20170524 |