CN106668488A - Medicine for treating insomnia and preparation method thereof - Google Patents

Medicine for treating insomnia and preparation method thereof Download PDF

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Publication number
CN106668488A
CN106668488A CN201710124410.0A CN201710124410A CN106668488A CN 106668488 A CN106668488 A CN 106668488A CN 201710124410 A CN201710124410 A CN 201710124410A CN 106668488 A CN106668488 A CN 106668488A
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parts
radix
medicine
ziziphi spinosae
semen ziziphi
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王恒飞
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/79—Schisandraceae (Schisandra family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine for treating insomnia and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: 13 to 17 parts of radix American ginseng, 8 to 10 parts of radix et rhizoma salviae miltiorrhizae, 13 to 17 parts of radix ophiopogonis, 4 to 6 parts of liquorice root, 13 to 17 parts of poria with hostwood, 20 to 30 parts of raw jujube kernel, 20 to 30 parts of prepared jujube kernel, 4 to 6 parts of rhizoma acori tatarinowii, 13 to 17 parts of Chinese angelica and 4 to 6 parts of fructus schisandrae chinensis. The preparation method of the medicine comprises the following steps: immersing medicinal materials with cold water for 25min to 35min, wherein the weight of the cold water is 4 times that of the total weight; after boiling with big fire, boiling with small fire for 25min to 35min; taking a decoction solution to obtain the medicine. The medicine for treating the insomnia, disclosed by the invention, is safe, has no toxic side effect and has a remarkable curative effect.

Description

It is a kind of to treat medicine of insomnia and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, relates in particular to a kind of medicine for treating insomnia, also relates to this and control Treat the preparation method of the medicine of insomnia.
Background technology
Insomnia is referred to cannot fall asleep or cannot keep sleep state, cause not having enough sleep.Hinder also known as falling asleep and maintaining to sleep Hinder, be that a variety of causes causes difficulty falling asleep, Depth of sleep or frequency be too short, early awakening and the length of one's sleep not enough or of poor quality etc., be A kind of commonly encountered diseases.Investigate according to World Health Organization (WHO), the whole world has 27% people there are sleeping problems, has 45% presence in Chinese Different degrees of sleep disorder.The reason for causing insomnia is a lot, and most people is in experience pressure, stimulation, excitement, anxiety ；When sick；To where High aititude；Or (such as the time difference during sleep rule change；Work in shifts etc.) can all have short Temporary property vigilance disorders.This kind of insomnia typically can improve with the disappearance of event or the elongation of time, but transience is had a sleepless night such as Dealing with groups of people improperly can cause chronic insomnia.Serious or continuous pressure, such as great body illness, serious family, work Or relationship problems etc. may result in short-term insomnia.This insomnia has obvious dependency with pressure.But chronic insomnia The reason for be it is very complicated and it is more difficult go to find, many chronic insomnias are caused by many reasons are combined.And it is psychological Factor is a principal element of chronic insomnia.Insomnia often brings greatly pain and psychological burden to patient.
The medicine for the treatment of insomnia at present is a lot, but western medicine can produce certain side effect.And health product are due to which The advantage of nontoxic or low toxicity, occurs in that and panoramic improves the health care of sleep class health product.Wherein, it is common with melatonin on market Health product are improved the health care of sleep for raw material.Traditional Chinese medicine in treating insomnia is set about overall dialectical, emphasizes " calming the nerves ", and its Small side effects is excellent Gesture.
The content of the invention
It is an object of the invention to provide the medicine that a kind for the treatment of evident in efficacy, with low cost, having no toxic side effect is had a sleepless night.
Another object of the present invention is to provide the preparation method of the medicine of the treatment insomnia.
A kind of medicine for treating insomnia of the present invention, by weight, including following raw material：
It is Radix Panacis Quinquefolii 13-17 parts, Radix Salviae Miltiorrhizae 8-10 parts, 13-17 parts Radix Ophiopogonis, Radix Glycyrrhizae 4-6 parts, Poria cum Radix Pini's 13-17 parts, raw Semen Ziziphi Spinosae 20-30 parts, ripe Semen Ziziphi Spinosae 20-30 parts, Rhizoma Acori Graminei 4-6 parts, Radix Angelicae Sinensis 13-17 parts, Fructus Schisandrae Chinensis 4-6 parts.
A kind of above-mentioned medicine for treating insomnia, by weight, preferred following raw material：
15 parts of Radix Panacis Quinquefolii, 10 parts of Radix Salviae Miltiorrhizae, 15 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae, 15 parts of Poria cum Radix Pini, raw 25 parts of Semen Ziziphi Spinosae, 25 parts of ripe Semen Ziziphi Spinosae, Rhizoma Acori Graminei 5 Part, 15 parts of Radix Angelicae Sinensis, 5 parts of Fructus Schisandrae Chinensis.
A kind of preparation method of medicine for treating insomnia of the present invention, comprises the following steps：
（1）Sample by weight：Radix Panacis Quinquefolii 13-17 parts, Radix Salviae Miltiorrhizae 8-10 parts, 13-17 parts Radix Ophiopogonis, Radix Glycyrrhizae 4-6 parts, Poria cum Radix Pini's 13-17 parts, Raw Semen Ziziphi Spinosae 20-30 parts, ripe Semen Ziziphi Spinosae 20-30 parts, Rhizoma Acori Graminei 4-6 parts, Radix Angelicae Sinensis 13-17 parts, Fructus Schisandrae Chinensis 4-6 parts；
（2）By above-mentioned medical material cold water soak 25-35min of 4 times of its gross weight, after boiling with high heat, then the 25- that simmers in water 35min, decocting liquid of fetching water, obtains final product.
The present invention compared with prior art, with obvious beneficial effect, as can be known from the above technical solutions：The present invention is from ocean Ginseng, Radix Salviae Miltiorrhizae, Radix Ophiopogonis, Radix Glycyrrhizae, Poria cum Radix Pini, raw Semen Ziziphi Spinosae, ripe Semen Ziziphi Spinosae, Rhizoma Acori Graminei, Radix Angelicae Sinensis, Fructus Schisandrae Chinensis are raw material, by the collaboration of each medicine Effect reaches that foster brain is calmed the nerves, restoring normal coordination between the heart and kidney, invigorating spleen and reinforcing stomach, yin nourishing are relieved inflammation or internal heat, soothing liver-QI for relieving depression the effect of.The medicine of the present invention has true The treatment insomnia cut, the effect for improving the health care of sleep quality, adjusting sleep rhythm.The Drug therapy of the present invention is had a sleepless night, is improved the health care of sleep, and pacifies It is completely without toxic and side effects, evident in efficacy.Clinical 3000 uses, total effective rate 100%.
Specific embodiment
The beneficial effect of medicine of the present invention is expanded on further below by way of test example.
Test example：The clinical observation of medicine of the present invention
1st, clinical data
Treatment case 3000, wherein：One full year of life at age 40-65, man 1490, female 1510.
2nd, diagnostic criteria：
《Disease of tcm Standardization of diagnosis and curative effect》.
3rd, Therapeutic Method：
Medicine obtained in the embodiment of the present invention is taken, three times a day, each 250ml, 10 days is a course for the treatment of, is taken a favorable turn within 3 days.
4th, curative effect determinate standard
It is effective：Symptom disappears；
Effectively：Symptom is relieved；
It is invalid：Symptom is not improved.
5th, therapeutic outcome：
Patient's use medicine of the present invention, effective 1500, effective 1500, invalid 0, obvious effective rate 50%, total effective rate 100%.
The preparation method of this medicine is illustrated by following examples.
Embodiment 1：
A kind of preparation method of the medicine for treating insomnia, comprises the following steps：
（1）Weigh：Radix Panacis Quinquefolii 13g, Radix Salviae Miltiorrhizae 10g, 13g Radix Ophiopogonis, Radix Glycyrrhizae 6g, Poria cum Radix Pini 13g, raw Semen Ziziphi Spinosae 30g, ripe Semen Ziziphi Spinosae 20g, Rhizoma Acori Graminei 6g, Radix Angelicae Sinensis 13g, Fructus Schisandrae Chinensis 6g；
（2）By above-mentioned medical material cold water soak 25min of 4 times of its gross weight, after boiling with high heat, then the 35min that simmers in water, take Decocting liquid, obtains final product.
Embodiment 2：
A kind of preparation method of the medicine for treating insomnia, comprises the following steps：
（1）Weigh：Radix Panacis Quinquefolii 15g, Radix Salviae Miltiorrhizae 8g, 15g Radix Ophiopogonis, Radix Glycyrrhizae 5g, Poria cum Radix Pini 15g, raw Semen Ziziphi Spinosae 25g, ripe Semen Ziziphi Spinosae 25g, Rhizoma Acori Graminei 5g, Radix Angelicae Sinensis 15g, Fructus Schisandrae Chinensis 5g；
（2）By above-mentioned medical material cold water soak 30min of 4 times of its gross weight, after boiling with high heat, then the 30min that simmers in water, take Decocting liquid, obtains final product.
Embodiment 3：
A kind of preparation method of the medicine for treating insomnia, comprises the following steps：
（1）Weigh：Radix Panacis Quinquefolii 17g, Radix Salviae Miltiorrhizae 8g, 17g Radix Ophiopogonis, Radix Glycyrrhizae 4g, Poria cum Radix Pini 17g, raw Semen Ziziphi Spinosae 20g, ripe Semen Ziziphi Spinosae 30g, Rhizoma Acori Graminei 4g, Radix Angelicae Sinensis 17g, Fructus Schisandrae Chinensis 4g；
（2）By above-mentioned medical material cold water soak 35min of 4 times of its gross weight, after boiling with high heat, then the 25min that simmers in water, take Decocting liquid, obtains final product.
The above, is only presently preferred embodiments of the present invention, not makees any pro forma restriction to the present invention, is appointed What any is simply repaiied according to what the technical spirit of the present invention made to above example without departing from technical solution of the present invention content Change, equivalent variations and modification, still fall within the range of technical solution of the present invention.

Claims (3)

1. a kind of medicine for treating insomnia, by weight, including following raw material：
It is Radix Panacis Quinquefolii 13-17 parts, Radix Salviae Miltiorrhizae 8-10 parts, 13-17 parts Radix Ophiopogonis, Radix Glycyrrhizae 4-6 parts, Poria cum Radix Pini's 13-17 parts, raw Semen Ziziphi Spinosae 20-30 parts, ripe Semen Ziziphi Spinosae 20-30 parts, Rhizoma Acori Graminei 4-6 parts, Radix Angelicae Sinensis 13-17 parts, Fructus Schisandrae Chinensis 4-6 parts.
2. a kind of medicine for treating insomnia as claimed in claim 1, by weight, including following raw material：
15 parts of Radix Panacis Quinquefolii, 10 parts of Radix Salviae Miltiorrhizae, 15 parts of Radix Ophiopogonis, 5 parts of Radix Glycyrrhizae, 15 parts of Poria cum Radix Pini, raw 25 parts of Semen Ziziphi Spinosae, 25 parts of ripe Semen Ziziphi Spinosae, Rhizoma Acori Graminei 5 Part, 15 parts of Radix Angelicae Sinensis, 5 parts of Fructus Schisandrae Chinensis.
3. a kind of preparation method of the medicine for treating insomnia, comprises the following steps：
（1）Sample by weight：Radix Panacis Quinquefolii 13-17 parts, Radix Salviae Miltiorrhizae 8-10 parts, 13-17 parts Radix Ophiopogonis, Radix Glycyrrhizae 4-6 parts, Poria cum Radix Pini's 13-17 parts, Raw Semen Ziziphi Spinosae 20-30 parts, ripe Semen Ziziphi Spinosae 20-30 parts, Rhizoma Acori Graminei 4-6 parts, Radix Angelicae Sinensis 13-17 parts, Fructus Schisandrae Chinensis 4-6 parts；
（2）By above-mentioned medical material cold water soak 25-35min of 4 times of its gross weight, after boiling with high heat, then the 25- that simmers in water 35min, decocting liquid of fetching water, obtains final product.
CN201710124410.0A 2017-03-03 2017-03-03 Medicine for treating insomnia and preparation method thereof Pending CN106668488A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111213753A (en) * 2020-03-16 2020-06-02 宁洱普义雾露山仙女茶厂 Tea drink with sleep-aiding function
CN113181123A (en) * 2021-05-12 2021-07-30 湖北中医药大学 Anmian granules and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102048946A (en) * 2009-10-28 2011-05-11 刘庆华 Traditional Chinese medicine formula for treating insomnia
US20110236358A1 (en) * 2008-12-12 2011-09-29 Stefano Sala Composition comprising isoflavones
CN104873752A (en) * 2015-05-11 2015-09-02 杭州美誉医药有限公司 Traditional Chinese medicine preparation for treating insomnia, preparation method and application

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110236358A1 (en) * 2008-12-12 2011-09-29 Stefano Sala Composition comprising isoflavones
CN102048946A (en) * 2009-10-28 2011-05-11 刘庆华 Traditional Chinese medicine formula for treating insomnia
CN104873752A (en) * 2015-05-11 2015-09-02 杭州美誉医药有限公司 Traditional Chinese medicine preparation for treating insomnia, preparation method and application

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孙世发等: "《中华医方. 内科篇. 心系篇》", 31 March 2015, 科学技术文献出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111213753A (en) * 2020-03-16 2020-06-02 宁洱普义雾露山仙女茶厂 Tea drink with sleep-aiding function
CN113181123A (en) * 2021-05-12 2021-07-30 湖北中医药大学 Anmian granules and preparation method thereof

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