CN106632525A - Method for separating sulfuric acid from a glucose-xylose solution - Google Patents
Method for separating sulfuric acid from a glucose-xylose solution Download PDFInfo
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- CN106632525A CN106632525A CN201611223534.6A CN201611223534A CN106632525A CN 106632525 A CN106632525 A CN 106632525A CN 201611223534 A CN201611223534 A CN 201611223534A CN 106632525 A CN106632525 A CN 106632525A
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- Prior art keywords
- sulfuric acid
- glucose
- xylose
- solution
- chromatographic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B17/00—Sulfur; Compounds thereof
- C01B17/69—Sulfur trioxide; Sulfuric acid
- C01B17/90—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/06—Separation; Purification
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
The present invention discloses a method for separating sulfuric acid from a glucose-xylose solution. The method is characterized by comprising the steps of enabling a mixed solution containing sulfuric acid, glucose and xylose to enter a chromatographic column filled with a chromatographic medium at the temperature of 0-100 DEG C, and then, eluting the mixed solution with an eluting agent to collect an eluate and a residual solution respectively, to obtain the glucose-xylose solution and a sulfuric acid solution, so that the sulfuric acid can be separated from glucose and xylose. The method for separating sulfuric acid from the glucose-xylose solution disclosed by the invention can directly separate sulfuric acid from a glucose-xylose solution by one step, and has advantages of easy process, good separation effects, low treatment cost and high product purity.
Description
Technical field
The present invention relates to feed separation field, more particularly to a kind of by sulfuric acid and the detached side of glucose and xylose solution
Method.
Background technology
In prior art, the solution of the glucose and xylose containing sulfuric acid (such as prepares glucose and xylose using acid hydrolyzation
The glucose and xylose solution that technique is obtained), it is difficult to directly separate in sulfuric acid and glucose and xylose solution, generally require
The separation of sulfuric acid and glucose and xylose solution is realized by the form of multiple process combinations such as neutralization, UF membrane, this virtually increases
Big production cost, wastes resource.
The content of the invention
For the problems referred to above, it is an object of the invention to design one kind can be simple and effective by sulfuric acid and glucose and xylose
The detached method of solution.
To reach above-mentioned purpose, technical scheme proposed by the invention is：A kind of sulfuric acid and glucose and xylose solution are separated
Method, it is characterised in that by by the mixed solution containing sulfuric acid and glucose and xylose under the conditions of 0-100 DEG C, into dress
Fill out the chromatographic column of chromatographic media, eluted by eluent, elutriant and Liquid Residue are collected respectively, obtain glucose and xylose solution and
Two kinds of products of sulfuric acid solution, realize the separation of sulfuric acid and glucose and xylose.
Further, the chromatographic media of filling is in described chromatographic column：Chromatographic resin, hydrogen form cation chromatography resin or
Sulfuric acid root type anion chromatographic resin.
Further, the mass ratio of sulfuric acid and glucose and xylose is 1 in the mixed liquor of described sulfuric acid and glucose and xylose:
99-99:1。
Further, the mixed liquor feedstock quality concentration of described sulfuric acid and glucose and xylose is 1%-70%.
Further, described chromatographic column post blade diameter length ratio is 1:1-1:20, feed rate is 0.05BV-1.5BV, elutes flow
For 0.1BV/h-5BV/h.
Further, described chromatographic column carries out the form of chromatographic isolation including true mobile bed chromatic, Simulation moving bed
The chromatographic column of chromatogram or batch-type chromatographic.
Further, described eluent is deionized water, desalted water or distilled water.
Further, described chromatographic column is using constant temperature chromatogram mode or temperature-induced displacement chromatography.
Using above-mentioned technical proposal, sulfuric acid of the present invention and the detached method of glucose and xylose solution being capable of a steps
Directly sulfuric acid and glucose and xylose solution are separated, with process is simple, good separating effect, processing cost is low and product is pure
The advantages of spending high.
Specific embodiment
With reference to specific embodiment, the present invention will be further described.
Embodiment 1
It is 40% by mass concentration, and sulfuric acid：Glucose and xylose mass ratio is 1:99 mixed solution；Under the conditions of 0 DEG C,
Into the chromatographic column of filling chromatographic resin, resin filling blade diameter length ratio 1:1st, feed rate 0.05BV/H, is eluted by deionized water,
Elution flow 0.1BV/H, collects respectively elutriant and Liquid Residue, and wherein elutriant is glucose and xylose solution, and purity is
90.5%；Liquid Residue is sulfuric acid solution, and purity is 94.5%.
Embodiment 2
It is 70% by mass concentration, and sulfuric acid：Glucose and xylose mass ratio is 50:50 mixed solution；In 100 DEG C of conditions
Under, into the chromatographic column of filling chromatographic resin, resin filling blade diameter length ratio 1:2nd, feed rate 0.2BV/H, is washed by deionization
Carry, elute flow 1BV/H, elutriant and Liquid Residue are collected respectively, wherein cleaning solution is glucose and xylose solution, and purity is
97.3%；Liquid Residue is sulfuric acid solution, and purity is 92.2%.
Embodiment 3
It is 1% by mass concentration, and sulfuric acid：Glucose and xylose mass ratio is 25:75 mixed solution；In 20 DEG C of conditions
Under, into the chromatographic column of filling chromatographic resin, resin filling blade diameter length ratio 1:20th, feed rate 1.5BV/H, is washed by deionization
Carry, elute flow 5BV/H, elute flow 5BV/H, elutriant and Liquid Residue are collected respectively, wherein cleaning solution is glucose and xylose
Solution, purity is 95%；Liquid Residue is sulfuric acid solution, and purity is 98%.
Embodiment 4
It is 30% by mass concentration, and sulfuric acid：Glucose and xylose mass ratio is 70:30 mixed solution；In 80 DEG C of conditions
Under, into the chromatographic column of filling Hydrogen chromatography resin, resin filling blade diameter length ratio 1:12nd, feed rate 0.05BV/H, by pure water
Elution, elutes flow 0.5BV/H, and elutriant and Liquid Residue are collected respectively, and wherein cleaning solution is glucose and xylose solution, and purity is
98%；Liquid Residue is sulfuric acid solution, and purity is 97.4%.
Embodiment 5
It is 25% by mass concentration, and sulfuric acid：Glucose and xylose mass ratio is 99:1 mixed solution；In 30 DEG C of conditions
Under, into the chromatographic column of filling Hydrogen chromatography resin, resin filling blade diameter length ratio 1:6th, feed rate 1BV/H, is eluted by pure water,
Elution flow 1BV/H, collects respectively elutriant and Liquid Residue, and wherein cleaning solution is glucose and xylose solution, and purity is 95%；It is residual
Liquid is stayed to be sulfuric acid solution, purity is 99%.
Embodiment 6
It is 45% by mass concentration, and sulfuric acid：Glucose and xylose mass ratio is 65:35 mixed solution；In 30 DEG C of conditions
Under, into the chromatographic column of filling sulfuric acid root type chromatography resin, resin filling blade diameter length ratio 1:10th, feed rate 0.5BV/H, by pure
Washing is carried, and elutes flow 1.5BV/H, collects elutriant and Liquid Residue respectively, and wherein cleaning solution is glucose and xylose solution, purity
For 99.5%；Liquid Residue is sulfuric acid solution, and purity is 98%.
Embodiment 7
It is 60% by mass concentration, and sulfuric acid：Glucose and xylose mass ratio is 15:85 mixed solution；In 50 DEG C of conditions
Under, into the chromatographic column of filling sulfuric acid root type chromatography resin, resin filling blade diameter length ratio 1:15th, feed rate 0.8BV/H, by pure
Washing is carried, and elutes flow 2.5BV/H, collects elutriant and Liquid Residue respectively, and wherein cleaning solution is glucose and xylose solution, purity
For 98.5%；Liquid Residue is sulfuric acid solution, and purity is 96%.
As known from the above, using sulfuric acid of the present invention and the detached method of glucose and xylose solution, can a step it is straight
Connect and separate in sulfuric acid and glucose and xylose solution, with process is simple, good separating effect, processing cost be low and product purity
High the advantages of.
Every technical staff's notice：Although the present invention is described according to above-mentioned specific embodiment, of the invention
Invention thought be not limited to that invention, the repacking of any utilization inventive concept will all include this patent protection of the patent right
In the range of.
Claims (8)
1. a kind of sulfuric acid and the detached method of glucose and xylose solution, it is characterised in that：By will containing sulfuric acid and glucose wood
The mixed solution of sugar, into the chromatographic column of filling chromatographic media, is eluted under the conditions of 0-100 DEG C by eluent, is collected respectively
Elutriant and Liquid Residue, obtain two kinds of products of glucose and xylose solution and sulfuric acid solution, realize sulfuric acid and glucose and xylose point
From.
2. a kind of sulfuric acid according to claim 1 and the detached method of glucose and xylose solution, it is characterised in that：Described
The chromatographic media of filling is in chromatographic column：Chromatographic resin, hydrogen form cation chromatography resin or sulfuric acid root type anion chromatographic resin.
3. a kind of sulfuric acid according to claim 1 and the detached method of glucose and xylose solution, it is characterised in that：Described
The mass ratio of sulfuric acid and glucose and xylose is 1 in the mixed liquor of sulfuric acid and glucose and xylose:99-99:1.
4. a kind of sulfuric acid according to claim 1 and the detached method of glucose and xylose solution, it is characterised in that：Described
The mixed liquor feedstock quality concentration of sulfuric acid and glucose and xylose is 1%-70%.
5. a kind of sulfuric acid according to claim 1 and the detached method of glucose and xylose solution, it is characterised in that：Described
Chromatographic column post blade diameter length ratio is 1:1-1:20, feed rate is 0.05BV-1.5BV, and elution flow is 0.1BV/h-5BV/h.
6. a kind of sulfuric acid according to claim 1 and the detached method of glucose and xylose solution, it is characterised in that：Described
Chromatographic column carries out the form of chromatographic isolation includes the chromatogram of true mobile bed chromatic, SMBC or batch-type chromatographic
Post.
7. a kind of sulfuric acid according to claim 1 and the detached method of glucose and xylose solution, it is characterised in that：Described
Eluent is deionized water, desalted water or distilled water.
8. a kind of sulfuric acid according to claim 1 and the detached method of glucose and xylose solution, it is characterised in that：Described
Chromatographic column is using constant temperature chromatogram mode or temperature-induced displacement chromatography.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611223534.6A CN106632525A (en) | 2016-12-27 | 2016-12-27 | Method for separating sulfuric acid from a glucose-xylose solution |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611223534.6A CN106632525A (en) | 2016-12-27 | 2016-12-27 | Method for separating sulfuric acid from a glucose-xylose solution |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111747998A (en) * | 2020-07-08 | 2020-10-09 | 江南大学 | Method for removing inorganic acid and acetic acid in xylose hydrolysate by using intermittent simulated moving bed chromatography |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1670028A (en) * | 2004-12-31 | 2005-09-21 | 中国科学院海洋研究所 | Method for preparing L-fucoidan in sea tangle |
| CN1763061A (en) * | 2005-04-20 | 2006-04-26 | 上海洁申实业有限公司 | Method for removing chlorhydric acid and ferrous chloride from hydrolysed biomass glyc solution by diluted acid |
| CN1850833A (en) * | 2006-05-22 | 2006-10-25 | 夏云丽 | Method for preparing xylosic alcohol using corn core |
-
2016
- 2016-12-27 CN CN201611223534.6A patent/CN106632525A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1670028A (en) * | 2004-12-31 | 2005-09-21 | 中国科学院海洋研究所 | Method for preparing L-fucoidan in sea tangle |
| CN1763061A (en) * | 2005-04-20 | 2006-04-26 | 上海洁申实业有限公司 | Method for removing chlorhydric acid and ferrous chloride from hydrolysed biomass glyc solution by diluted acid |
| CN1850833A (en) * | 2006-05-22 | 2006-10-25 | 夏云丽 | Method for preparing xylosic alcohol using corn core |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111747998A (en) * | 2020-07-08 | 2020-10-09 | 江南大学 | Method for removing inorganic acid and acetic acid in xylose hydrolysate by using intermittent simulated moving bed chromatography |
| CN111747998B (en) * | 2020-07-08 | 2022-04-01 | 江南大学 | Method for removing inorganic acid and acetic acid in xylose hydrolysate by using intermittent simulated moving bed chromatography |
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Application publication date: 20170510 |