CN106621013A - Internal type bladder irrigation chemotherapy pump - Google Patents
Internal type bladder irrigation chemotherapy pump Download PDFInfo
- Publication number
- CN106621013A CN106621013A CN201710079196.1A CN201710079196A CN106621013A CN 106621013 A CN106621013 A CN 106621013A CN 201710079196 A CN201710079196 A CN 201710079196A CN 106621013 A CN106621013 A CN 106621013A
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- Prior art keywords
- bladder
- chemotherapy pump
- administration
- medicine
- irrigation
- Prior art date
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- 238000002512 chemotherapy Methods 0.000 title claims abstract description 93
- 230000002262 irrigation Effects 0.000 title claims abstract description 59
- 238000003973 irrigation Methods 0.000 title claims abstract description 59
- 239000003814 drug Substances 0.000 claims abstract description 96
- 229940079593 drug Drugs 0.000 claims abstract description 19
- 238000004891 communication Methods 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 8
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 230000002209 hydrophobic effect Effects 0.000 claims description 5
- 241000883990 Flabellum Species 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000000741 silica gel Substances 0.000 claims description 4
- 229910002027 silica gel Inorganic materials 0.000 claims description 4
- 239000002775 capsule Substances 0.000 claims 2
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 abstract description 12
- 210000004877 mucosa Anatomy 0.000 abstract description 10
- 210000002700 urine Anatomy 0.000 abstract description 10
- 238000002271 resection Methods 0.000 abstract description 8
- 239000012895 dilution Substances 0.000 abstract description 5
- 238000010790 dilution Methods 0.000 abstract description 5
- 206010005003 Bladder cancer Diseases 0.000 abstract description 4
- 210000003932 urinary bladder Anatomy 0.000 description 96
- 210000004400 mucous membrane Anatomy 0.000 description 18
- 230000002632 myometrial effect Effects 0.000 description 12
- 238000002347 injection Methods 0.000 description 11
- 239000007924 injection Substances 0.000 description 11
- 230000007170 pathology Effects 0.000 description 11
- 201000001531 bladder carcinoma Diseases 0.000 description 10
- 230000002980 postoperative effect Effects 0.000 description 10
- 208000010570 urinary bladder carcinoma Diseases 0.000 description 10
- 238000001802 infusion Methods 0.000 description 9
- 206010028980 Neoplasm Diseases 0.000 description 8
- 230000010412 perfusion Effects 0.000 description 7
- 230000000694 effects Effects 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 230000002459 sustained effect Effects 0.000 description 4
- 238000011282 treatment Methods 0.000 description 3
- 210000004881 tumor cell Anatomy 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 208000035269 cancer or benign tumor Diseases 0.000 description 2
- 210000000080 chela (arthropods) Anatomy 0.000 description 2
- 230000000306 recurrent effect Effects 0.000 description 2
- 201000005112 urinary bladder cancer Diseases 0.000 description 2
- 208000009458 Carcinoma in Situ Diseases 0.000 description 1
- 229910001069 Ti alloy Inorganic materials 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 206010046555 Urinary retention Diseases 0.000 description 1
- 208000012931 Urologic disease Diseases 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000002574 cystoscopy Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000003073 embolic effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000002649 immunization Methods 0.000 description 1
- 230000003053 immunization Effects 0.000 description 1
- 201000004933 in situ carcinoma Diseases 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 238000010899 nucleation Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 208000014001 urinary system disease Diseases 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
Abstract
The invention discloses an internal type bladder irrigation chemotherapy pump, which comprises a chemotherapy pump elastic medicine storage bag, wherein an administration soft hose, which communicates with the chemotherapy pump elastic medicine storage bag, is arranged at one end of the chemotherapy pump elastic medicine storage bag; the end, away from the chemotherapy pump elastic medicine storage bag, of the administration soft hose is provided with an administration hard pipe which communicates with the administration soft hose; a clamp is arranged on the administration hard pipe; an administration pipe, which communicates with the chemotherapy pump elastic medicine storage bag, is arranged at the other end of the chemotherapy pump elastic medicine storage bag; and a valve is arranged on the administration pipe. According to the chemotherapy pump provided by the invention, medicines can be continuously applied to mucosa of a pathologically changed bladder wall through drop irrigation; the chemotherapy pump is fixed to the bladder mucosa by virtue of the clamp, and the medicines, which is applied through drop irrigation in a pipeline, can be siphoned and spread to surrounding bladder walls at the first time through the bladder mucosa, and finally the medicines can be siphoned and spread to the entire bladder wall; then, the medicines are mixed with urine, so that dilution of the medicines, before getting into contact with the bladder wall, is greatly relieved; an administration position is relatively precise; and the medicines, which are continuously discharged through drop irrigation, has a sufficient time to get into contact with the bladder wall, so that a recurrence rate of normuscle invasive bladder cancer which accepts transurethral resection of bladder tumor is reduced.
Description
Technical field
The invention mainly relates to On Irrigation of Bladder Chemotherapy field, specifically a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump.
Background technology
Non- Myometrial involvement carcinoma of urinary bladder (Ta, T1, Tis) accounts for the 70% of initial tumor of bladder, and wherein Ta accounts for 70%, T1 and accounts for
20%, Tis account for 10%.According to risk of recurrence and the difference of prognosis, non-Myometrial involvement carcinoma of urinary bladder can be divided into three groups：Low danger,
It is middle danger, high-risk.The essential therapeutic arsenals of non-Myometrial involvement carcinoma of urinary bladder are transurethral resection of bladder tumor, non-Myometrial involvement
After carcinoma of urinary bladder electrocision, considerable tumor recurrence is the T1 phase bladders of particularly middle and high differentiation because Neoplasm residual is caused
Cancer, according to the literature first Neoplasm residual rate can reach 33.8%-36% after electrocision.Non- Myometrial involvement carcinoma of urinary bladder is passed through
There is very high Postoperative recurrent rate after Urinary Bladder tumour electrocision, subset of patients even can progress to Myometrial involvement bladder
Cancer.The simple row underwent transurethral resection of bladder tumor of carcinoma in situ can not solve the problems, such as postoperative high relapse rate and progression of disease.Cause
This, non-Myometrial involvement bladder cancer patients carry out it is postoperative auxiliary irrigation of bladder make it is necessary, comprising On Irrigation of Bladder Chemotherapy and bladder
Perfusion immunization therapy.At present perfusion opportunity and scheme are as follows：1st, immediate postoperative On Irrigation of Bladder Chemotherapy, principle is immediate postoperative perfusion
Chemotherapy can kill the tumour cell of the tumour cell and surface of a wound residual sent out in art, for prevention of tumor cell seeding, Ying
Complete in postoperative 24 hours.Postoperative perfusion chemotherapy as early as possible, if completing best results, all non-fleshes in operating room or recovery interior
Layer invasive bladder cancer recommends immediate postoperative On Irrigation of Bladder Chemotherapy；2nd, early postoperation and maintain On Irrigation of Bladder Chemotherapy, middle danger and
High-order non-Myometrial involvement carcinoma of urinary bladder at once after On Irrigation of Bladder Chemotherapy, should receive successive treatment after surgery.Bladder is maintained to fill
Note chemotherapy can reduce the recurrence rate of tumour.Chinese urological diseases diagnoses and treatment guide 2014 editions recommends perfusion scheme for early
Phase irrigates：Postoperative 4-8 is all, weekly irrigation of bladder；Perfusion is maintained afterwards：Monthly, the 6-12 months are maintained.Irrigation of bladder
The effect for the treatment of is related to urine ph values, chemotherapeutics concentration, and wherein chemotherapeutics concentration ratio drug dose is even more important.Adopt at present
The irrigation of bladder method for taking is：Medicine is disposably injected by catheter for bladder, retains 0.5-2 hours.Irrigation of bladder at present
The shortcoming of embolic chemotherapy is as follows：
1st, the solubility of chemotherapeutics, as urine is constantly secreted, Bladder Volume increases, and gradually dilutes, and medicine is dense after dilution
Degree reduces that the effect of chemotherapy can be reduced, and then after a few hours, bladder urination can discharge high amount of drug, fail to play medicine
Effect.
2nd, the method for disposably injecting bladder through catheter by medicine, the position that medicine is attached to bladder is inaccurate,
It is insufficient with the time of contact of pathology the bladder wall, it is possible to which that the bladder wall at tumor of bladder TURP fails well and chemotherapeutics
It is fully contacted, causes Postoperative recurrent rate to increase.
The content of the invention
In order to solve deficiency of the prior art, the present invention provides a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump, by built-in
On Irrigation of Bladder Chemotherapy pump, can be by mucous membrane at sustained drug drip irrigation to pathology the bladder wall；Fixed by fixture due to hard tube is administered
In mucous membrane of urinary bladder, medicine can diffuse to the bladder wall around, most time first time through pipeline drip irrigation by mucous membrane of urinary bladder siphon
Afterwards to whole the bladder wall, then again with urine mix, greatly reduce dilution of the medicine before contacting with the bladder wall；Meanwhile, by
Pathology is fixed on by fixture in administration hard tube and cuts off the bladder wall surrounding mucosa, therefore administering position is relatively accurate, medicine passes through
Drip irrigation is persistently discharged, and the time of contact of such medicine and the bladder wall is just very abundant, so as to reduce non-Myometrial involvement carcinoma of urinary bladder
Recurrence rate after row underwent transurethral resection of bladder tumor.
The present invention for achieving the above object, is achieved through the following technical solutions：
A kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump, including chemotherapy pump elasticity medicine storing bag, the chemotherapy pump elasticity medicine storing bag
One end arranges administration flexible pipe in communication, and the administration flexible pipe arranges in communication away from one end of chemotherapy pump elasticity medicine storing bag
Administration hard tube, fixture is set on the administration hard tube, the other end of the chemotherapy pump elasticity medicine storing bag arranges in communication
Medicine-pouring pipe, on the medicine-pouring pipe valve is arranged.
The chemotherapy pump elasticity medicine storing bag is oval ball structure, and flexible pipe, medicine-pouring pipe is administered respectively positioned at its major axis
Both ends.
The valve is butterfly valve, and including the circular baffle plate that can seal medicine-pouring pipe, the center of the circular baffle plate sets
Swing handle is put, the swing handle is connected with medicine-pouring pipe rotation and its one end is passed outside medicine-pouring pipe.
The fixture, administration hard tube and medicine-pouring pipe are hard memory material.
The fixture is fan-shaped fixture, and the width of its both sides flabellum is 0.5cm, and length is 0.5cm.
The internal diameter of the administration hard tube is 0.04cm～0.06cm, the length 0.05cm～0.15cm of the administration hard tube.
The internal diameter of the administration flexible pipe is 0.04cm～0.06cmcm, and the length of the administration flexible pipe 2 is 1cm～2cm.
The administration flexible pipe is the administration flexible pipe of silica gel material.
The length of the medicine-pouring pipe is 0.5cm～0.7cm, and internal diameter is 0.2cm～0.4cm.
The outer surface coated with nano hydrophobic coating of the chemotherapy pump elasticity medicine storing bag.
Prior art is contrasted, beneficial effect of the present invention is：
The present invention, can be by mucous membrane at sustained drug drip irrigation to pathology the bladder wall by built-in On Irrigation of Bladder Chemotherapy pump；By
Mucous membrane of urinary bladder is fixed on by fixture in the administration hard tube of built-in On Irrigation of Bladder Chemotherapy pump of the invention, medicine through pipeline drip irrigation,
Time first time the bladder wall around can be diffused to by mucous membrane of urinary bladder siphon, finally to whole the bladder wall, then again and urine
Mixing, greatly reduces dilution of the medicine before contacting with the bladder wall；Simultaneously as administration hard tube is fixed on pathology by fixture
Excision the bladder wall surrounding mucosa, therefore administering position is relatively accurate, and medicine is persistently discharged by drip irrigation, such medicine and the bladder wall
Time of contact just very fully, so as to the recurrence after the row underwent transurethral resection of bladder tumor for reducing non-Myometrial involvement carcinoma of urinary bladder
Rate.
Description of the drawings
Structural representation when accompanying drawing 1 is unimplanted medicine of the invention.
Accompanying drawing 2 is the structural representation after injection of medicine of the present invention.
Accompanying drawing 3 is structural representation when valve is closed.
Accompanying drawing 4 is structural representation when valve is opened.
Label shown in accompanying drawing：1st, chemotherapy pump elasticity medicine storing bag；2nd, flexible pipe is administered；3rd, hard tube is administered；4th, fixture；5th, injection
Pipe；6th, valve；7th, circular baffle plate；8th, swing handle.
Specific embodiment
With reference to the drawings and specific embodiments, the invention will be further described.It should be understood that these embodiments are merely to illustrate
The present invention rather than restriction the scope of the present invention.In addition, it is to be understood that after the content for having read instruction of the present invention, this area
Technical staff can make various changes or modifications to the present invention, and these equivalent form of values equally fall within scope defined herein
It is interior.
A kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump, including chemotherapy pump elasticity medicine storing bag 1, the chemotherapy pump elasticity medicine storing bag 1
One end administration flexible pipe 2 in communication is set, the administration flexible pipe 2 away from one end of chemotherapy pump elasticity medicine storing bag 1 arrange with
Connection administration hard tube 3, administration hard tube 3 with administration flexible pipe 2 be sealedly and fixedly connected, be administered hard tube 3 be provided with drug row mouth, be used for
The medicine in chemotherapy pump elasticity medicine storing bag 1 is discharged, fixture 4 is set on the administration hard tube 3, be sandwiched in the present invention by fixture 4
At surrounding mucosa after bladder excision pathology, the other end of the chemotherapy pump elasticity medicine storing bag 1 arranges medicine-pouring pipe in communication
5, for injection of medicine in chemotherapy pump elasticity medicine storing bag 1, valve 6 being arranged on the medicine-pouring pipe 5.
When using the present invention, after the completion of transurethral resection of bladder tumor tumour, resectoscope system is released, retain outer tube, first
The medicine-pouring pipe 5 of chemotherapy pump elasticity medicine storing bag 1 is connected into (temporarily should not injection, be easy to insert bladder) with infusion strap extension tube,
Then On Irrigation of Bladder Chemotherapy pump Jing outer tubes of the present invention are inserted bladder by the other end indwelling of infusion strap extension tube in external
It is interior (chemotherapy pump elasticity medicine storing bag 1 along outer tube insert in bladder when, the maximum gauge of its circumferencial direction is preferably not more than and is
0.6cm, so that the present invention can be inserted easily in bladder by outer tube)；Then (ureteroscope compares wing to insert ureteroscope
Guang mirror is thinner, occupies little space), then laparoscope elastic separating plier two is inserted by outer tube, fixture 4 is separated into clamp with laparoscope
At the surrounding mucosa that bladder cuts off after pathology, the present invention is set to be fixed on the bladder wall；Then by indwelling in external transfusion skin
Bar extension tube injects chemotherapeutics 25ml, and now chemotherapy pump elasticity medicine storing bag 1 expands, after the completion of chemotherapeutics injection, in urine output
The lower valve 6 closed on medicine-pouring pipe 5 using the laparoscope elastic separating plier inserted of pipe mirror display screen observation, then will with laparoscope elastic separating plier
Infusion strap extension tube is separated with medicine-pouring pipe 5, and infusion strap extension tube is retracted in vitro；Finally exit two laparoscopes to separate
Pincers and ureteroscope, pull out resectoscope system garment pipe, and operation terminates.The drip irrigation speed of On Irrigation of Bladder Chemotherapy pump of the present invention is by giving
The elasticity decision of the thickness and chemotherapy pump elasticity medicine storing bag 1 of medicine hard tube 3 and administration flexible pipe 2, is adjusted to about 7 days drip off
25ml chemotherapeutics, after one week, resectoscope outer tube, ureteroscope and laparoscope point are inserted again in row cystoscopy again
From pincers, then valve 6 is opened using laparoscope elastic separating plier, infusion strap extension tube is inserted into bladder using laparoscope elastic separating plier,
Under the observation of ureteroscope, make medicine-pouring pipe 5 connect infusion strap extension tube, and re-injected by infusion strap extension tube
25ml chemotherapeutics, is then shut off valve 6, and infusion strap extension tube and medicine-pouring pipe 5 are separated, and extracts infusion strap extension tube out,
Repeat abovementioned steps, allow patient to carry out second and continue drip irrigation type perfusion chemotherapy.According to state of an illness needs, medication cycle can be adjusted
With injection dosage.If bladder has multiple tumour, after electroblation, multiple On Irrigation of Bladder Chemotherapy pumps can be inserted, respectively with fixture 4
Lesion surrounding mucosa is clamped, the bladder wall mucous membrane is fixed on, chemotherapy is irrigated.The present invention passes through built-in On Irrigation of Bladder Chemotherapy
Pump, can be by mucous membrane at sustained drug drip irrigation to pathology the bladder wall；Because the administration hard tube 3 of the present invention is fixed on by fixture 4
Mucous membrane of urinary bladder, medicine can diffuse to the bladder wall around, finally time first time through pipeline drip irrigation by mucous membrane of urinary bladder siphon
To whole the bladder wall, then mix with urine again, greatly reduce dilution of the medicine before contacting with the bladder wall.(during first time
Between mean, medicine out with regard to drip irrigation to mucous membrane of urinary bladder, if it is former by catheter by the whole injection bladder of medicine,
After first medicine can mix with bladder residual urine liquid, mixed liquor has contacted Chemotherapy with bladder again.In addition, with urine not
Disconnected secretion, being mixed the method for the whole disposable injection bladder of medicine, medicine and urine by catheter in the past, drug concentration
Can gradually dilute, drug effect is gradually lowered, and the method for adopting internally-arranged type bladder chemotherapy pump, medicine is through delivery tube drip irrigation to bladder
Mucous membrane carries out siphon disperse, and medicine is directly and mucous membrane of urinary bladder has contacted chemotherapy effect, will not reduce the concentration of medicine.) while, by
Pathology is fixed on by fixture 4 in the administration hard tube 3 of On Irrigation of Bladder Chemotherapy pump of the present invention and cuts off the bladder wall surrounding mucosa, therefore given
Medicine position is relatively accurate, and medicine is persistently discharged by drip irrigation, and the time of contact of such medicine and the bladder wall is just very abundant, so as to drop
Recurrence rate after the row underwent transurethral resection of bladder tumor of low non-Myometrial involvement carcinoma of urinary bladder.
Further, chemotherapy pump elasticity medicine storing bag 1 is oval ball structure, and flexible pipe 2, medicine-pouring pipe 5 is administered distinguishes
Positioned at the both ends of its major axis.Before non-injection, it is 0.5cm that chemotherapy pump elasticity medicine storing bag 1 is about major axis radius, and minor axis radius is
0.3cm, high radius is the oval ball of 0.3cm；It is 2.1cm that major axis radius is about after injection, and minor axis radius is 1.7cm, high
Radius is the oval ball of 1.7cm.When the present invention is sent into bladder, not to the chemotherapy pump elasticity injection of medicine of medicine storing bag 1, this
The volume of sample chemotherapy pump elasticity medicine storing bag 1 is smaller, is easy to chemotherapy pump elasticity medicine storing bag 1 be sent into bladder；Due to chemotherapy pump
Elastic medicine storing bag 1 is oval ball structure, while being easy to chemotherapy pump elasticity medicine storing bag 1 be inserted in bladder, moreover it is possible to insert phase
To more medicine, during the present invention to be sent into bladder by resectoscope outer tube, along the length of chemotherapy pump elasticity medicine storing bag 1
Degree direction is advanced, and the size along the circumferential chemotherapy pump elasticity medicine storing bag 1 of resectoscope outer tube is less, is easy to the present invention in resectoscope
Advance in outer tube.
Further, the valve 6 is butterfly valve, including the circular baffle plate 7 that can seal medicine-pouring pipe 5, the circle
The centrally disposed swing handle 8 of baffle plate 7, the swing handle 8 is connected with the rotation of medicine-pouring pipe 5 and its one end is passed outside medicine-pouring pipe 5
Portion, is easy to the opening and closure of medicine-pouring pipe 5.
Further, the fixture 4, administration hard tube 3 and medicine-pouring pipe 5 are hard memory material, preferably titanium alloy
Material, its is harmless, can be in forever indwelling human body.Fixture 4 can be the V-type titanium folder commonly used in medical science, be easy to fix
On mucous membrane of urinary bladder.
Further, the fixture 4 is fan-shaped fixture, and the width of its both sides flabellum is 0.5cm, and length is 0.5cm, is easy to
It is fixed on mucous membrane of urinary bladder.
Further, it is described administration hard tube 3 internal diameter be 0.04cm～0.06cm, the length of the administration hard tube 3
0.05cm～0.15cm.The internal diameter of the administration flexible pipe 2 is 0.04cm～0.06cm, the length of the administration flexible pipe 2 be 1cm～
2cm.The internal diameter size of administration flexible pipe 2 and administration hard tube 3 affects the dropper speed of the present invention, and internal diameter is bigger, and dropper speed is faster,
Internal diameter is less, and dropper speed is slower.
Further, the administration flexible pipe 2 is the administration flexible pipe 2 of silica gel material.
Further, the length of the medicine-pouring pipe 5 is 0.5cm～0.7cm, and internal diameter is 0.2cm～0.4cm.
Further, the outer surface coated with nano hydrophobic coating of the chemotherapy pump elasticity medicine storing bag 1, On Irrigation of Bladder Chemotherapy pump
Indwelling bladder overlong time, easily forms calculus, and row cystoscope takes out after general indwelling January, according to conditions of patients needs, can
To insert new On Irrigation of Bladder Chemotherapy pump, continual cure again.The coating of nano-sized hydrophobic coating can reduce the formation of calculus, prolong
The indwelling time of long intravesical chemotherapy pump.
Embodiment
A kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump, including chemotherapy pump elasticity medicine storing bag 1, the chemotherapy pump elasticity medicine storing bag 1
One end administration flexible pipe 2 in communication is set, the administration flexible pipe 2 away from one end of chemotherapy pump elasticity medicine storing bag 1 arrange with
Connection administration hard tube 3, fixture 4 is set on the administration hard tube 3, the other end of chemotherapy pump elasticity medicine storing bag 1 is arranged
Medicine-pouring pipe 5 in communication, arranges valve 6 on the medicine-pouring pipe 5.The chemotherapy pump elasticity medicine storing bag 1 is oval ball structure,
And flexible pipe 2, medicine-pouring pipe 5 is administered respectively positioned at the both ends of its major axis.The valve 6 is butterfly valve, including can seal note
The circular baffle plate 7 of pencil 5, the centrally disposed swing handle 8 of the circular baffle plate 7, the swing handle 8 is rotated with medicine-pouring pipe 5
Connect and its one end is passed outside medicine-pouring pipe 5.The fixture 4, administration hard tube 3 and medicine-pouring pipe 5 are hard memory material.It is described
Fixture 4 is fan-shaped fixture, and the width of its both sides flabellum is 0.5cm, and length is 0.5cm.It is described administration hard tube 3 internal diameter be
0.05cm, the length of the administration hard tube 3 is 0.1cm.The internal diameter of the administration flexible pipe 2 is 0.05cm, the administration flexible pipe 2
Length is 1.4cm.The administration flexible pipe 2 is the administration flexible pipe 2 of silica gel material.The length of the medicine-pouring pipe 5 be 0.6cm, internal diameter
For 0.3cm.The outer surface coated with nano hydrophobic coating of the chemotherapy pump elasticity medicine storing bag 1.The beneficial effect of the present embodiment is：
By built-in On Irrigation of Bladder Chemotherapy pump, can be by mucous membrane at sustained drug drip irrigation to pathology the bladder wall；Pass through due to hard tube 3 is administered
Fixture 4 is fixed on mucous membrane of urinary bladder, and medicine can diffuse to surrounding time first time through pipeline drip irrigation by mucous membrane of urinary bladder siphon
The bladder wall, finally to whole the bladder wall, then again with urine mix, greatly reduce medicine dilute before contacting with the bladder wall
Release；Simultaneously as administration hard tube 3 is fixed on pathology by fixture 4 cuts off the bladder wall surrounding mucosa, therefore administering position is relatively smart
Standard, medicine is persistently discharged by drip irrigation, and the time of contact of such medicine and the bladder wall is just very abundant, so as to reduce non-Myometrial involvement
Recurrence rate after the row underwent transurethral resection of bladder tumor of property carcinoma of urinary bladder.
Claims (10)
1. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump, is characterized in that：Including chemotherapy pump elasticity medicine storing bag (1), the chemotherapy pump bullet
Property medicine storing bag (1) one end administration flexible pipe (2) in communication is set, administration flexible pipe (2) is away from chemotherapy pump elasticity drug storage
One end of capsule (1) arranges administration hard tube (3) in communication, and on administration hard tube (3) fixture (4), the chemotherapy pump are arranged
The other end of elastic medicine storing bag (1) arranges medicine-pouring pipe (5) in communication, and valve (6) is arranged on the medicine-pouring pipe (5).
2. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：The chemotherapy pump elasticity drug storage
Capsule (1) is oval ball structure, and flexible pipe (2), medicine-pouring pipe (5) is administered respectively positioned at the both ends of its major axis.
3. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：The valve (6) is butterfly
Valve, including the circular baffle plate (7) that can seal medicine-pouring pipe (5), the centrally disposed swing handle (8) of the circular baffle plate (7),
The swing handle (8) is connected with medicine-pouring pipe (5) rotation and its one end passes medicine-pouring pipe (5) outside.
4. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：The fixture (4), administration are hard
Pipe (3) and medicine-pouring pipe (5) are hard memory material.
5. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：The fixture (4) is sector
Fixture, the width of its both sides flabellum is 0.5cm, and length is 0.5cm.
6. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：Administration hard tube (3)
Internal diameter is 0.04cm～0.06cm, the length 0.05cm～0.15cm of the administration hard tube (3).
7. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：Administration flexible pipe (2)
Internal diameter is 0.04cm～0.06cmcm, and the length of the administration flexible pipe 2 is 1cm～2cm.
8. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：It is described administration flexible pipe (2) be
The administration flexible pipe (2) of silica gel material.
9. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：The length of the medicine-pouring pipe (5)
Spend for 0.5cm～0.7cm, internal diameter is 0.2cm～0.4cm.
10. a kind of internally-arranged type On Irrigation of Bladder Chemotherapy pump according to claim 1, is characterized in that：The chemotherapy pump elasticity storage
The outer surface coated with nano hydrophobic coating of anther sac (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710079196.1A CN106621013A (en) | 2017-02-14 | 2017-02-14 | Internal type bladder irrigation chemotherapy pump |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710079196.1A CN106621013A (en) | 2017-02-14 | 2017-02-14 | Internal type bladder irrigation chemotherapy pump |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106621013A true CN106621013A (en) | 2017-05-10 |
Family
ID=58845233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710079196.1A Pending CN106621013A (en) | 2017-02-14 | 2017-02-14 | Internal type bladder irrigation chemotherapy pump |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106621013A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112843370A (en) * | 2021-01-13 | 2021-05-28 | 温州医科大学附属第一医院 | Auxiliary bladder perfusion device |
Citations (7)
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| CN112843370A (en) * | 2021-01-13 | 2021-05-28 | 温州医科大学附属第一医院 | Auxiliary bladder perfusion device |
| CN112843370B (en) * | 2021-01-13 | 2023-04-25 | 温州医科大学附属第一医院 | Device for assisting bladder perfusion |
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Application publication date: 20170510 |