CN106620667A - L-carnitine compound having effects of losing weight and reducing grease and preparation method thereof - Google Patents

L-carnitine compound having effects of losing weight and reducing grease and preparation method thereof Download PDF

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Publication number
CN106620667A
CN106620667A CN201611157732.7A CN201611157732A CN106620667A CN 106620667 A CN106620667 A CN 106620667A CN 201611157732 A CN201611157732 A CN 201611157732A CN 106620667 A CN106620667 A CN 106620667A
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China
Prior art keywords
parts
weight
reducing
lipid
fat
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Pending
Application number
CN201611157732.7A
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Chinese (zh)
Inventor
曾凡跃
戚玉如
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Qinnan Qinzhou District Science And Technology Information Institute
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Qinnan Qinzhou District Science And Technology Information Institute
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Priority to CN201611157732.7A priority Critical patent/CN106620667A/en
Publication of CN106620667A publication Critical patent/CN106620667A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/465Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases

Abstract

The invention discloses an L-carnitine compound having effects of losing weight and reducing grease and a preparation method thereof. The L-carnitine compound is prepared from the following formula components in parts by weight: 15-25 parts of lotus leaves, 5-7 parts of L-carnitine, 6-8 parts of glutamine, 3-5 parts of fatty acid, 5-7 parts of soybean peptide, 5-7 parts of creatine, 5-7 parts of broadleaf holly leaves, 6-8 parts of rhizoma alismatis, 5-7 parts of triacylglycerol enzyme, 4-6 parts of amylopsin, 10-20 parts of hawthorn and 2-3 parts of salt. The L-carnitine compound is beneficial to the reduction of redundant fat in body. The L-carnitine compound can accelerate the decomposition of fat in body and the conversion of fat into energy and meanwhile can restrain the absorption of body for fat and saccharides, so that the dual-purpose of natural control and weight losing can be achieved.

Description

A kind of l-cn combination of Weight-reducing and lipid-lowering effect and preparation method thereof
Technical field
The present invention relates to natural products drug world, combines in particular to a kind of l-cn of Weight-reducing and lipid-lowering effect And preparation method thereof.
Background technology
Obesity refers to that feed heat exceedes human consumption amount and with storage as fat in internal, causes body weight to be above standard A kind of physiological phenomenon.It is fat with angiocardiopathy, type ii diabetes, hypertension, dyslipidemia, hyperuricemia, some swell Various diseases such as knurl and sleep disordered breathing are closely related.1997 the World Health Organization (WHO) announce that obesity is one Plant disease.WHO thinks that obesity is listed as the great society problem of the world four with AIDS, drug and alcohol abuse.Medical circle also with fertilizer Fat relevant coronary heart disease, hypertension, hyperlipidemia, diabetes, cerebrovas-cularaccident are referred to as " dead quintet ".The preventing and treating of science and Improve the social concern that obesity symptom has become common concern in world wide.
The content of the invention
The invention provides l-cn combination of a kind of Weight-reducing and lipid-lowering effect and preparation method thereof, the present invention contributes to subtracting Few fat unnecessary in vivo.Said composition can accelerate decomposition fatty in body and be converted into energy, while suppressing body to fat The absorption of fat and carbohydrate, so as to reaching natural contral and lowering the purpose of body weight.
For achieving the above object, the present invention provides following technical scheme:
L-cn combination of a kind of Weight-reducing and lipid-lowering effect and preparation method thereof, by following mass fraction formula components group Into:Lotus leaf 15-25 parts, l-cn 5-7 parts, glutamine 6-8 parts, aliphatic acid 3-5 parts, Soybean Peptide 5-7 part, creatine 5-7 parts, Ilex Latifolia Thunb 5-7 parts, rhizoma alismatis 6-8 parts, triglyceride enzyme 5-7 parts, amylopsin 4-6 parts, hawthorn 10-20 parts, salt 2-3 parts.
Further:It is made up of following mass fraction formula components:15 parts of lotus leaf, 5 parts of l-cn, 6 parts of glutamine, fat 3 parts of fat acid, 5 parts of Soybean Peptide, 5 parts of creatine, 5 parts of Ilex Latifolia Thunb, 6 parts of rhizoma alismatis, 5 parts of triglyceride enzyme, 4 parts of amylopsin, hawthorn 10 parts, 2 parts of salt.
Further:It is made up of following mass fraction formula components:20 parts of lotus leaf, 6 parts of l-cn, 7 parts of glutamine, fat 4 parts of fat acid, 6 parts of Soybean Peptide, 6 parts of creatine, 6 parts of Ilex Latifolia Thunb, 7 parts of rhizoma alismatis, 6 parts of triglyceride enzyme, 5 parts of amylopsin, hawthorn 15 parts, 2.5 parts of salt.
Further:It is made up of following mass fraction formula components:25 parts of lotus leaf, 7 parts of l-cn, 8 parts of glutamine, fat 5 parts of fat acid, 7 parts of Soybean Peptide, 7 parts of creatine, 7 parts of Ilex Latifolia Thunb, 8 parts of rhizoma alismatis, 7 parts of triglyceride enzyme, 6 parts of amylopsin, hawthorn 20 parts, 3 parts of salt.
Further:Preparation method of the present invention has following steps:
Step one, each raw material weighed in the l-cn composition, pulverize and sieve, standby;
Step 2, weigh the pharmaceutically acceptable excipient, by the excipient and each raw material described in step one according to After the equivalent method of progressively increasing is well mixed, the l-cn preparation is prepared.
The invention has the beneficial effects as follows:
1st, the present invention contributes to reducing fat unnecessary in vivo;
2nd, said composition can accelerate decomposition fatty in body and be converted into energy, while suppressing body to fat and sugar class Absorption, so as to reaching natural contral and lowering the purpose of body weight.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described, Obviously, described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all Belong to the scope of protection of the invention.
Embodiment one:
A kind of l-cn combination of Weight-reducing and lipid-lowering effect is made up of following mass fraction formula components:Lotus leaf 15-25 parts, L-cn 5-7 parts, glutamine 6-8 parts, aliphatic acid 3-5 parts, Soybean Peptide 5-7 part, creatine 5-7 parts, Ilex Latifolia Thunb 5-7 parts, pool Rush down 6-8 parts, triglyceride enzyme 5-7 parts, amylopsin 4-6 parts, hawthorn 10-20 parts, salt 2-3 parts.
Embodiment two:
A kind of l-cn combination of Weight-reducing and lipid-lowering effect is made up of following mass fraction formula components:15 parts of lotus leaf, a left side 5 parts of carnitine of rotation, 6 parts of glutamine, 3 parts of aliphatic acid, 5 parts of Soybean Peptide, 5 parts of creatine, 5 parts of Ilex Latifolia Thunb, 6 parts of rhizoma alismatis, three acyls are sweet 5 parts of oily enzyme, 4 parts of amylopsin, 10 parts of hawthorn, 2 parts of salt.
Embodiment three:
A kind of l-cn combination of Weight-reducing and lipid-lowering effect is made up of following mass fraction formula components:20 parts of lotus leaf, a left side 6 parts of carnitine of rotation, 7 parts of glutamine, 4 parts of aliphatic acid, 6 parts of Soybean Peptide, 6 parts of creatine, 6 parts of Ilex Latifolia Thunb, 7 parts of rhizoma alismatis, three acyls are sweet 6 parts of oily enzyme, 5 parts of amylopsin, 15 parts of hawthorn, 2.5 parts of salt.
Example IV:
A kind of l-cn combination of Weight-reducing and lipid-lowering effect is made up of following mass fraction formula components:25 parts of lotus leaf, a left side 7 parts of carnitine of rotation, 8 parts of glutamine, 5 parts of aliphatic acid, 7 parts of Soybean Peptide, 7 parts of creatine, 7 parts of Ilex Latifolia Thunb, 8 parts of rhizoma alismatis, three acyls are sweet 7 parts of oily enzyme, 6 parts of amylopsin, 20 parts of hawthorn, 3 parts of salt.
Embodiment five:
A kind of preparation method preparation method of the l-cn combination of Weight-reducing and lipid-lowering effect comprises the steps:
Step one, each raw material weighed in the l-cn composition, pulverize and sieve, standby;
Step 2, weigh the pharmaceutically acceptable excipient, by the excipient and each raw material described in step one according to After the equivalent method of progressively increasing is well mixed, the l-cn preparation is prepared.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that for clarity those skilled in the art should Using specification as an entirety, the technical scheme in each embodiment can also Jing it is appropriately combined, form those skilled in the art Understandable other embodiment.

Claims (5)

1. the l-cn combination of a kind of Weight-reducing and lipid-lowering effect, it is characterised in that:It is made up of following mass fraction formula components:
Lotus leaf 15-25 parts, l-cn 5-7 parts, glutamine 6-8 parts, aliphatic acid 3-5 parts, Soybean Peptide 5-7 part, creatine 5-7 Part, Ilex Latifolia Thunb 5-7 parts, rhizoma alismatis 6-8 parts, triglyceride enzyme 5-7 parts, amylopsin 4-6 parts, hawthorn 10-20 parts, salt 2-3 parts.
2. the l-cn combination of a kind of Weight-reducing and lipid-lowering effect according to claim 1, it is characterised in that:By following quality Number formula components are constituted:
15 parts of lotus leaf, 5 parts of l-cn, 6 parts of glutamine, 3 parts of aliphatic acid, 5 parts of Soybean Peptide, 5 parts of creatine, 5 parts of Ilex Latifolia Thunb, pool Rush down 6 parts, 5 parts of triglyceride enzyme, 4 parts of amylopsin, 10 parts of hawthorn, 2 parts of salt.
3. the l-cn combination of a kind of Weight-reducing and lipid-lowering effect according to claim 1, it is characterised in that:By following quality Number formula components are constituted:
20 parts of lotus leaf, 6 parts of l-cn, 7 parts of glutamine, 4 parts of aliphatic acid, 6 parts of Soybean Peptide, 6 parts of creatine, 6 parts of Ilex Latifolia Thunb, pool Rush down 7 parts, 6 parts of triglyceride enzyme, 5 parts of amylopsin, 15 parts of hawthorn, 2.5 parts of salt.
4. the l-cn combination of a kind of Weight-reducing and lipid-lowering effect according to claim 1, it is characterised in that:By following quality Number formula components are constituted:
25 parts of lotus leaf, 7 parts of l-cn, 8 parts of glutamine, 5 parts of aliphatic acid, 7 parts of Soybean Peptide, 7 parts of creatine, 7 parts of Ilex Latifolia Thunb, pool Rush down 8 parts, 7 parts of triglyceride enzyme, 6 parts of amylopsin, 20 parts of hawthorn, 3 parts of salt.
5. the preparation method that a kind of a kind of l-cn of Weight-reducing and lipid-lowering effect according to claim 1 is combined, its feature It is:Comprise the steps:
Step one, each raw material weighed in the l-cn composition, pulverize and sieve, standby;
Step 2, the pharmaceutically acceptable excipient is weighed, by the excipient and each raw material described in step one according to equivalent After the method for progressively increasing is well mixed, the l-cn preparation is prepared.
CN201611157732.7A 2016-12-15 2016-12-15 L-carnitine compound having effects of losing weight and reducing grease and preparation method thereof Pending CN106620667A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109363163A (en) * 2018-11-21 2019-02-22 苏州衍生生物科技有限公司 A kind of health food and preparation method thereof

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Patent Citations (3)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109363163A (en) * 2018-11-21 2019-02-22 苏州衍生生物科技有限公司 A kind of health food and preparation method thereof

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