CN106620096A - 纯植物提取物止痒消炎药膏及其制备方法 - Google Patents
纯植物提取物止痒消炎药膏及其制备方法 Download PDFInfo
- Publication number
- CN106620096A CN106620096A CN201611094157.0A CN201611094157A CN106620096A CN 106620096 A CN106620096 A CN 106620096A CN 201611094157 A CN201611094157 A CN 201611094157A CN 106620096 A CN106620096 A CN 106620096A
- Authority
- CN
- China
- Prior art keywords
- parts
- ash
- grey
- ointment
- pure plant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种纯植物提取物止痒消炎药膏及其制备方法,其特征在于,所述药膏主要由以下重量份的原料提取得到:灰灰菜25‑35、蛇莓18‑22、蝎子草18‑22、益母草13‑17、野菊花12‑14、琉璃苣12‑14、桑枝8‑12、槐枝8‑12、白芷8‑12、甘草8‑12、黄柏5‑9、荷叶5‑8、椿皮2‑4、乌梅3‑5、石榴皮3‑5、薄荷6‑8、金银花5‑8、苦参4‑6以及青黛0.2‑0.3,该药膏将可达到快速杀虫止痒,解毒消肿的功效,经实践证明蚊虫叮咬后将该药膏涂于患处2‑3分钟便可以达到止痒消肿的效果。
Description
技术领域
本发明涉及植物提取技术领域,尤其涉及一种纯植物提取物止痒消炎药膏及其制备方法。
背景技术
灰灰菜,(学名:Chenopodium album Linn)又名藜,别名野灰菜,灰蓼头草等,为藜科一年生草本植物。食用灰灰菜能够预防贫血,促进儿童生长发育,对中老年缺钙者也有一定保健功能。另外,全草还含有挥发油、藜碱等特有物质,能够防止消化道寄生虫、消除口臭。灰灰菜嫩茎叶含蛋白质、脂肪、糖类,特别是其中极丰富的胡萝卜素和维生素C有助于增强人体免疫功能。目前,灰灰菜作为食品逐渐得到人们重视,而且,有研究表明,灰灰菜还有一定抗癌的功效,在抗癌药物中得到研究与开发。但是,目前还没有将灰灰菜用于皮肤消炎止痒的应用中。
蛇莓(学名:Duchesnea indica(Andr.)Focke),别名蛇泡草,为蔷薇科,多年生草本植物,全草可入药,有清热解毒、活血散瘀、收敛止血作用,又能治毒蛇咬伤,敷治疔疮等;并用于杀灭蝇蛆。蝎子草,又名八宝景天,为多年生草本花卉,具有祛风利湿,活血散瘀,止血止痛等功效。目前,还没有将灰灰菜与蛇莓及蝎子草配合应用于药膏的制备。
发明内容
本发明的一个目的是解决至少上述问题,并提供至少后面将说明的优点。
本发明还有一个目的是提供一种纯植物提取物止痒消炎药膏,将多种植物合理配合,混合提取,能够止痒消炎。
本发明还有一个目的是提供一种纯植物提取物止痒消炎药膏的制备方法,其能够使配方中的各种成分充分发挥其功效,提高作用效果。
为了实现根据本发明的这些目的和其它优点,提供了以下技术:
一种纯植物提取物止痒消炎药膏,其特征在于,主要由以下重量份的原料提取得到:
灰灰菜25-35、蛇莓18-22、蝎子草18-22、益母草13-17、野菊花12-14、琉璃苣12-14、桑枝8-12、槐枝8-12、白芷8-12、甘草8-12、黄柏5-9、荷叶5-8、椿皮2-4、乌梅3-5、石榴皮3-5、薄荷6-8、金银花5-8、苦参4-6以及青黛0.2-0.3。
优选的是,所述的纯植物提取物止痒消炎药膏,主要由以下重量份的原料提取得到:
灰灰菜29、蛇莓20、蝎子草20、益母草15、野菊花13、琉璃苣13、桑枝10、槐枝10、白芷10、甘草10、黄柏7、荷叶6、椿皮3、乌梅4、石榴皮4、薄荷7、金银花7、苦参5以及青黛0.2。
一种纯植物提取物止痒消炎药膏的制备方法,其特征在于,主要包含以下步骤:
步骤1、将灰灰菜、蛇莓、蝎子草、益母草、野菊花、琉璃苣、桑枝、槐枝、白芷、甘草、黄柏、荷叶、椿皮、乌梅、石榴皮、薄荷、金银花、苦参以及青黛进行低温速冻20-30分钟,速冻温度为-22℃-18℃,然后进行低温粉碎,粉碎过程中温度控制在0-4℃,得到组合物粉末;
步骤2、将组合物粉末与8-12倍体积的质量浓度为65%的乙醇溶液进行浸提,反复浸提2-4次,分别过滤,将所得过滤所得液混合,得浸提液。
步骤3、将浸提液进行旋蒸,旋蒸温度控制在45-60℃,旋蒸至剩余物呈膏状,得组合物提取物。
步骤4、另取灰灰菜全株5重量份与3倍体积的沸水混合煮制5-10分钟,过滤得灰灰菜汁液,晾至常温备用。
步骤5、另取灰灰菜全株低温干燥粉碎,过500目筛,得到灰灰菜粉末。
步骤6、取48-56重量份的组合物提取物、35-42重量份灰灰菜汁液、8-16重量份灰灰菜粉末、0.5-2重量份甘油以及0.5-2重量份白凡士林混合,调和至膏状,即得所述纯植物提取物止痒消炎药膏。
优选的是,所述的纯植物提取物止痒消炎药膏的制备方法,步骤2中,所述浸提的温度为30~40℃,时间为50~60分钟。
优选的是,所述的纯植物提取物止痒消炎药膏的制备方法,步骤4中,所述灰灰菜汁液的另一种提取方法是:
5.1将5重量份灰灰菜全株粉碎并与5-10倍体积的质量浓度为5~6%的氯化钠溶液混合得到混合溶液。
5.2采用脉动压差法对所述混合溶液进行提取,即将脉动压力室温度设定为30~35℃,高压设定为300~400kPa,低压设定为50~0kPa,高低压时间比设定为1~6min:13~19min提取得到灰灰菜汁液。
本发明至少包括以下有益效果:
本发明提供了一种纯植物提取物止痒消炎药膏,该止痒消炎药膏主要包括灰灰菜、蛇莓、蝎子草、益母草、野菊花、琉璃苣、桑枝、槐枝、白芷、甘草、黄柏、荷叶、椿皮、乌梅、石榴皮、薄荷、金银花、苦参以及青黛,其中灰灰菜具有清热、止痛、杀虫的功效;蛇莓具有清热解毒、活血散瘀、收敛止血的作用;蝎子草具有祛风利湿、活血散瘀、止血止痛的功效;益母草具有消肿、解毒、活血化瘀的功效;野菊花具有疏散风热、消肿解毒的功效;琉璃苣具有解毒、消肿、镇痛的功效;桑枝具有祛风除湿、止痒、消肿止痛的功效;槐枝具有止血止痛、消除疮疡的功效;白芷具有祛风散湿、美白、生肌止痛的功效;甘草具有清热解毒、抗炎、抗过敏的功效;黄柏具有解毒、止痒、燥湿的功效;荷叶具有消炎止血、排毒镇痛的功效;乌梅具有消炎止痛、治疗胬肉外突的功效;椿皮、石榴皮、薄荷、金银花、苦参以及青黛具有消炎解毒的功效;该药膏将各组分充分混合可达到快速杀虫止痒,解毒消肿的功效,经实践证明蚊虫叮咬后将该药膏涂于患处2-3分钟便可以达到止痒消肿的功效。
本发明提供了一种纯植物提取物止痒消炎药膏的制备方法,其中,首先将灰灰菜、蛇莓、蝎子草、益母草、野菊花、琉璃苣、桑枝、槐枝、白芷、甘草、黄柏、荷叶、椿皮、乌梅、石榴皮、薄荷、金银花、苦参以及青黛进行低温冷藏,可以使其生物活性物质的功效得到充分的发挥;然后在低温条件下干燥粉碎灰灰菜全株,可以避免其有效成分的丧失,抑制细菌的繁殖,防止灰灰菜汁液受到污染。
本发明的其它优点、目标和特征将部分通过下面的说明体现,部分还将通过对本发明的研究和实践而为本领域的技术人员所理解。
具体实施方式
下面本发明做进一步的详细说明,以令本领域技术人员参照说明书文字能够据以实施。
应当理解,本文所使用的诸如“具有”、“包含”以及“包括”术语并不配出一个或多个其它元件或其组合的存在或添加。
一种纯植物提取物止痒消炎药膏,其特征在于,主要由以下重量份的原料提取得到:
灰灰菜25-35、蛇莓18-22、蝎子草18-22、益母草13-17、野菊花12-14、琉璃苣12-14、桑枝8-12、槐枝8-12、白芷8-12、甘草8-12、黄柏5-9、荷叶5-8、椿皮2-4、乌梅3-5、石榴皮3-5、薄荷6-8、金银花5-8、苦参4-6以及青黛0.2-0.3。
该药膏将各组分充分混合可达到快速杀虫止痒,解毒消肿的功效,经实践证明蚊虫叮咬后将该药膏涂于患处2-3分钟便可以达到止痒消肿的功效。
一个优选方案中,所述的纯植物提取物止痒消炎药膏,主要由以下重量份的原料提取得到:
灰灰菜29、蛇莓20、蝎子草20、益母草15、野菊花13、琉璃苣13、桑枝10、槐枝10、白芷10、甘草10、黄柏7、荷叶6、椿皮3、乌梅4、石榴皮4、薄荷7、金银花7、苦参5以及青黛0.2。
在本方案中,灰灰菜具有清热、止痛、杀虫的功效;蛇莓具有清热解毒、活血散瘀、收敛止血的作用;蝎子草具有祛风利湿、活血散瘀、止血止痛的功效;益母草具有消肿、解毒、活血化瘀的功效;野菊花具有疏散风热、消肿解毒的功效;琉璃苣具有解毒、消肿、镇痛的功效;桑枝具有祛风除湿、止痒、消肿止痛的功效;槐枝具有止血止痛、消除疮疡的功效;白芷具有祛风散湿、美白、生肌止痛的功效;甘草具有清热解毒、抗炎、抗过敏的功效;黄柏具有解毒、止痒、燥湿的功效;荷叶具有消炎止血、排毒镇痛的功效;乌梅具有消炎止痛、治疗胬肉外突的功效;椿皮、石榴皮、薄荷、金银花、苦参以及青黛具有消炎解毒的功效。
一种纯植物提取物止痒消炎药膏的制备方法,其特征在于,主要包含以下步骤:
步骤1、将灰灰菜、蛇莓、蝎子草、益母草、野菊花、琉璃苣、桑枝、槐枝、白芷、甘草、黄柏、荷叶、椿皮、乌梅、石榴皮、薄荷、金银花、苦参以及青黛进行低温速冻20-30分钟,速冻温度为-22℃-18℃,然后进行低温粉碎,粉碎过程中温度控制在0-4℃,得到组合物粉末;
步骤2、将组合物粉末与8-12倍体积的质量浓度为65%的乙醇溶液进行浸提,反复浸提2-4次,分别过滤,将所得过滤所得液混合,得浸提液。
步骤3、将浸提液进行旋蒸,旋蒸温度控制在45-60℃,旋蒸至剩余物呈膏状,得组合物提取物。
步骤4、另取灰灰菜全株5重量份与3倍体积的沸水混合煮制5-10分钟,过滤得灰灰菜汁液,晾至常温备用。
步骤5、另取灰灰菜全株低温干燥粉碎,过500目筛,得到灰灰菜粉末。
步骤6、取48-56重量份的组合物提取物、35-42重量份灰灰菜汁液、8-16重量份灰灰菜粉末、0.5-2重量份甘油以及0.5-2重量份白凡士林混合,调和至膏状,即得所述纯植物提取物止痒消炎药膏。
其中,对灰灰菜、蛇莓、蝎子草、益母草、野菊花、琉璃苣、桑枝、槐枝、白芷、甘草、黄柏、荷叶、椿皮、乌梅、石榴皮、薄荷、金银花、苦参以及青黛进行低温冷藏,可以最大程度的保持其有效成分的活性,使药膏的功效充分发挥;其中,低温干燥粉碎灰灰菜全株,可以避免其有效成分的丧失,抑制细菌的繁殖,防止灰灰菜汁液受到污染。
一个优选方案中,所述的纯植物提取物止痒消炎药膏的制备方法,步骤2中,所述浸提的温度为30~40℃,时间为50~60分钟。
一个优选方案中,所述的纯植物提取物止痒消炎药膏的制备方法,步骤4中,所述灰灰菜汁液的另一种提取方法是:
5.1将5重量份灰灰菜全株粉碎并与5-10倍体积的质量浓度为5~6%的氯化钠溶液混合得到混合溶液。
5.2采用脉动压差法对所述混合溶液进行提取,即将脉动压力室温度设定为30~35℃,高压设定为300~400kPa,低压设定为50~0kPa,高低压时间比设定为1~6min:13~19min提取得到灰灰菜汁液。
在本方案中,采用脉动压差法提取得到灰灰菜汁液,可以使有效成分的提取率达到70~80%。
实施例1
步骤1、将灰灰菜25g、蛇莓18g、蝎子草18g、益母草13g、野菊花12g、琉璃苣12g、桑枝8g、槐枝8g、白芷8g、甘草8g、黄柏5g、荷叶5g、椿皮2g、乌梅3g、石榴皮3g、薄荷6g、金银花5g、苦参4g以及青黛0.2g进行低温速冻20分钟,速冻温度为-22℃,然后进行低温粉碎,粉碎过程中温度控制在0℃,得到组合物粉末;
步骤2、将组合物粉末与8倍体积的质量浓度为65%的乙醇溶液进行浸提,反复浸提2次,分别过滤,将所得过滤所得液混合,得浸提液;
步骤3、将浸提液进行旋蒸,旋蒸温度控制在45℃,旋蒸至剩余物呈膏状,得组合物提取物;
步骤4、另取灰灰菜全株100g与3倍体积的沸水混合煮制5分钟,过滤得灰灰菜汁液,晾至常温备用;
步骤5、另取20g灰灰菜全株低温干燥粉碎,过500目筛,得到灰灰菜粉末;
步骤6、取100g的组合物提取物、72g灰灰菜汁液、17g灰灰菜粉末、1g甘油以及1g白凡士林混合,调和至膏状,即得所述纯植物提取物止痒消炎药膏。
实施例2
步骤1、将灰灰菜29g、蛇莓20g、蝎子草20g、益母草15g、野菊花13g、琉璃苣13g、桑枝10g、槐枝10g、白芷10g、甘草10g、黄柏7g、荷叶6g、椿皮3g、乌梅4g、石榴皮4g、薄荷7g、金银花7g、苦参5g以及青黛0.2g进行低温速冻25分钟,速冻温度为-20℃,然后进行低温粉碎,粉碎过程中温度控制在2℃,得到组合物粉末;
步骤2、将组合物粉末与10倍体积的质量浓度为65%的乙醇溶液进行浸提,反复浸提3次,分别过滤,将所得过滤所得液混合,得浸提液;
步骤3、将浸提液进行旋蒸,旋蒸温度控制在50℃,旋蒸至剩余物呈膏状,得组合物提取物;
步骤4、另取灰灰菜全株150g与3倍体积的沸水混合煮制8分钟,过滤得灰灰菜汁液,晾至常温备用;
步骤5、另取40g灰灰菜全株低温干燥粉碎,过500目筛,得到灰灰菜粉末;
步骤6、取120g组合物提取物、92g灰灰菜汁液、28g灰灰菜粉末、2g甘油以及2g白凡士林混合,调和至膏状,即得所述纯植物提取物止痒消炎药膏。
实施例3
步骤1、将灰灰菜35g、蛇莓22g、蝎子草22g、益母草17g、野菊花14g、琉璃苣14g、桑枝12g、槐枝12g、白芷12g、甘草12g、黄柏9g、荷叶8g、椿皮4g、乌梅5g、石榴皮5g、薄荷8g、金银花8g、苦参6g以及青黛0.3g进行低温速冻30分钟,速冻温度为-18℃,然后进行低温粉碎,粉碎过程中温度控制在4℃,得到组合物粉末;
步骤2、将组合物粉末与12倍体积的质量浓度为65%的乙醇溶液进行浸提,反复浸提4次,分别过滤,将所得过滤所得液混合,得浸提液;
步骤3、将浸提液进行旋蒸,旋蒸温度控制在60℃,旋蒸至剩余物呈膏状,得组合物提取物;
步骤4、将200g灰灰菜全株粉碎并与10倍体积的质量浓度为6%的氯化钠溶液混合得到混合溶液;
步骤5、采用脉动压差法对所述混合溶液进行提取,即将脉动压力室温度设定为35℃,高压设定为400kPa,低压设定为0kPa,高低压时间比设定为5min:18min提取得到灰灰菜汁液。
步骤6、另取灰灰菜全株低温干燥粉碎,过500目筛,得到灰灰菜粉末;
步骤7、取150g重量份的组合物提取物、113g灰灰菜汁液、43g灰灰菜粉末、5g甘油以及5g白凡士林混合,调和至膏状,即得所述纯植物提取物止痒消炎药膏。
尽管本发明的实施方案已公开如上,但其并不仅仅限于说明书和实施方式中所列运用,它完全可以被适用于各种适合本发明的领域,对于熟悉本领域的人员而言,可容易地实现另外的修改,因此在不背离权利要求及等同范围所限定的一般概念下,本发明并不限于特定的细节。
Claims (5)
1.一种纯植物提取物止痒消炎药膏,其特征在于,主要由以下重量份的原料提取得到:
灰灰菜25-35、蛇莓18-22、蝎子草18-22、益母草13-17、野菊花12-14、琉璃苣12-14、桑枝8-12、槐枝8-12、白芷8-12、甘草8-12、黄柏5-9、荷叶5-8、椿皮2-4、乌梅3-5、石榴皮3-5、薄荷6-8、金银花5-8、苦参4-6以及青黛0.2-0.3。
2.如权利要求1所述的纯植物提取物止痒消炎药膏,其特征在于,主要由以下重量份的原料提取得到:
灰灰菜29、蛇莓20、蝎子草20、益母草15、野菊花13、琉璃苣13、桑枝10、槐枝10、白芷10、甘草10、黄柏7、荷叶6、椿皮3、乌梅4、石榴皮4、薄荷7、金银花7、苦参5以及青黛0.2。
3.一种如权利要求1所述的纯植物提取物止痒消炎药膏的制备方法,其特征在于,主要包含以下步骤:
步骤1、将灰灰菜、蛇莓、蝎子草、益母草、野菊花、琉璃苣、桑枝、槐枝、白芷、甘草、黄柏、荷叶、椿皮、乌梅、石榴皮、薄荷、金银花、苦参以及青黛进行低温速冻20-30分钟,速冻温度为-22℃-18℃,然后进行低温粉碎,粉碎过程中温度控制在0-4℃,得到组合物粉末;
步骤2、将组合物粉末与8-12倍体积的质量浓度为65%的乙醇溶液进行浸提,反复浸提2-4次,分别过滤,将所得过滤所得液混合,得浸提液;
步骤3、将浸提液进行旋蒸,旋蒸温度控制在45-60℃,旋蒸至剩余物呈膏状,得组合物提取物;
步骤4、另取灰灰菜全株5重量份与3倍体积的沸水混合煮制5-10分钟,过滤得灰灰菜汁液,晾至常温备用;
步骤5、另取灰灰菜全株低温干燥粉碎,过500目筛,得到灰灰菜粉末;
步骤6、取48-56重量份的组合物提取物、35-42重量份灰灰菜汁液、8-16重量份灰灰菜粉末、0.5-2重量份甘油以及0.5-2重量份白凡士林混合,调和至膏状,即得所述纯植物提取物止痒消炎药膏。
4.如权利要求3所述的纯植物提取物止痒消炎药膏的制备方法,其特征在于,步骤2中,所述浸提的温度为30~40℃,时间为50~60分钟。
5.如权利要求3所述的纯植物提取物止痒消炎药膏的制备方法,其特征在于,步骤4中,所述灰灰菜汁液的另一种提取方法是:
5.1将5重量份灰灰菜全株粉碎并与5-10倍体积的质量浓度为5~6%的氯化钠溶液混合得到混合溶液;
5.2采用脉动压差法对所述混合溶液进行提取,即将脉动压力室温度设定为30~35℃,高压设定为300~400kPa,低压设定为50~0kPa,高低压时间比设定为1~6min:13~19min提取得到灰灰菜汁液。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611094157.0A CN106620096A (zh) | 2016-12-02 | 2016-12-02 | 纯植物提取物止痒消炎药膏及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611094157.0A CN106620096A (zh) | 2016-12-02 | 2016-12-02 | 纯植物提取物止痒消炎药膏及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106620096A true CN106620096A (zh) | 2017-05-10 |
Family
ID=58814788
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201611094157.0A Pending CN106620096A (zh) | 2016-12-02 | 2016-12-02 | 纯植物提取物止痒消炎药膏及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106620096A (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113244382A (zh) * | 2021-06-11 | 2021-08-13 | 江南大学 | 一种止痒消肿组合物及其制备方法和应用 |
CN114569516A (zh) * | 2022-03-31 | 2022-06-03 | 广东金发科技有限公司 | 一种止痒消炎组合物和止痒消炎湿巾及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1927300A (zh) * | 2006-09-06 | 2007-03-14 | 北京润德康医药技术有限公司 | 一种用于皮肤瘙痒的中药组合物 |
CN104474008A (zh) * | 2014-12-10 | 2015-04-01 | 遵义医学院 | 一种金银花痱子水及其制备方法 |
-
2016
- 2016-12-02 CN CN201611094157.0A patent/CN106620096A/zh active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1927300A (zh) * | 2006-09-06 | 2007-03-14 | 北京润德康医药技术有限公司 | 一种用于皮肤瘙痒的中药组合物 |
CN104474008A (zh) * | 2014-12-10 | 2015-04-01 | 遵义医学院 | 一种金银花痱子水及其制备方法 |
Non-Patent Citations (1)
Title |
---|
肖定远等: "《当代中医皮肤科临床家丛书》", 30 September 2015, 中国医药科技出版社 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113244382A (zh) * | 2021-06-11 | 2021-08-13 | 江南大学 | 一种止痒消肿组合物及其制备方法和应用 |
CN114569516A (zh) * | 2022-03-31 | 2022-06-03 | 广东金发科技有限公司 | 一种止痒消炎组合物和止痒消炎湿巾及其制备方法 |
CN114569516B (zh) * | 2022-03-31 | 2024-01-12 | 广东金发科技有限公司 | 一种止痒消炎组合物和止痒消炎湿巾及其制备方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Kumar et al. | Recent trends in potential traditional Indian herbs Emblica officinalis and its medicinal importance | |
Haq | The ethno botanical uses of medicinal plants of Allai Valley, Western Himalaya Pakistan | |
Guarino et al. | Ethnobotanical study of the Sannio area, Campania, southern Italy | |
CN105532755A (zh) | 一种新型植物源果树杀虫剂、制备方法及其应用 | |
CN105594765A (zh) | 环保型杀虫剂 | |
CN105994450A (zh) | 一种茶叶的中草药杀虫剂及其制备方法 | |
CN103814969A (zh) | 驱虫剂制备方法 | |
CN105901038A (zh) | 防治蔬菜根线虫的植物杀虫剂及其制备方法 | |
CN109566671A (zh) | 一种农作物中药杀虫剂及其制备方法和应用 | |
Gautam et al. | Diversity and usage custom of plants of western Himachal Pradesh, India-Part I | |
Sukumaran et al. | Usage of medicinal plants by two cultural communities of Kanyakumari district, Tamil Nadu, South India | |
CN106214571B (zh) | 一种苦楝驱蚊虫组合物及其制备方法和应用 | |
Lalzarzovi et al. | Traditional use of medicinal plants found within Aizawl city in Mizoram, India | |
CN102336610B (zh) | 促进植物伤口愈合的中药组合物 | |
Lalramnghinglova | Ethnobotany of Mizoram-a preliminary survey | |
CN106620096A (zh) | 纯植物提取物止痒消炎药膏及其制备方法 | |
CN105012902A (zh) | 一种治疗跌打损伤的药酒及其制备方法 | |
CN104510641A (zh) | 天然睡莲除湿疹婴儿油 | |
KR101236366B1 (ko) | 천연산 조성물을 이용한 입욕제와 손목베개 | |
KR101145498B1 (ko) | 천연한방추출물을 포함하는 바디워시제조방법 및 그 바디워시조성물 | |
CN104706840A (zh) | 一种防治蚊虫叮咬的复方茶树精油 | |
CN104056062A (zh) | 一种美白祛斑化瘢的外用药物 | |
Prasad et al. | Ethnobotany of the Kannikars of South Tamil Nadu | |
Ashitha Ganesh et al. | Diversity of ethnomedicinal plants and their therapeutic uses in Western Ghats region of Kodagu district, Karnataka, India | |
CN103920124B (zh) | 一种杀菌护肤冻疮膏 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170510 |
|
RJ01 | Rejection of invention patent application after publication |