CN106591402A - Tylosin fermentation formula - Google Patents
Tylosin fermentation formula Download PDFInfo
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- CN106591402A CN106591402A CN201510659604.1A CN201510659604A CN106591402A CN 106591402 A CN106591402 A CN 106591402A CN 201510659604 A CN201510659604 A CN 201510659604A CN 106591402 A CN106591402 A CN 106591402A
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- powder
- formula
- tylosin
- fish meal
- calcium carbonate
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- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
The invention relates to a tylosin fermentation formula. The formula mainly comprises, by weight, 0.8-2.0% of corn flour, 0.5-1.8% of fibroin powder, 0.5-1.5% of wheat bran powder, 0.1-1.0% of cotton seed cake powder, 0.05-0.15% of potassium chloride, 0.02-0.08% of betaine hydrochloride, 0.01-0.07% of diammonium phosphate, 0.0001-0.0008% of cobalt chloride, 0.0001-0.0008% of nickel sulfate, 0.1-0.6% of light calcium carbonate, 1-4% of soybean oil, and the balance of water. The low-cost fibroin powder is adopted in the new formula to substitute fish meal, so the production cost is effectively reduced; and the formula contains no fish meal, so the influences of the quality of the fish meal on the quality and the fermentation effect of a fermentation liquid are reduced, and the production stability is improved.
Description
Technical field
The invention belongs to fermentation technical field, the new fermentating formula of more particularly to a kind of tylosin.
Background technology
Tylosin is by streptomyces fradiae（Streptomyces fradiae）The special antibiotic of the hexa-atomic macrolide poultry of a class ten for producing, is widely used as both at home and abroad veterinary drug and feed addictive.
Major part all contains fish meal in the adopted culture medium prescription of tylosin fermentation at present, and the fish meal of domestic production is all mixing fish meal, containing animal bone powder, feather meal etc. in fish meal, affects the quality and ferment effect of zymotic fluid.In addition, the price for buying pure fish meal is higher, and easily affected by fishing off season, increased buying difficulty and production cost.
The content of the invention
To solve the above problems, the new formula of the present invention substitutes fish meal with lower-cost fibroin powder, effectively reduces production cost；And newly formula does not contain fish meal, reduces impact of the quality of fishmeal to zymotic fluid quality and ferment effect, improves the stability of production.
For achieving the above object, the present invention adopts embodiments below：
A kind of tylosin fermentating formula, it is characterised in that by weight percentage, the formula mainly includes following components：Corn flour 0.8 ~ 2.0, fibroin powder 0.5 ~ 1.8, seitan powder 0.5 ~ 1.5, cottonseed meal 0.1 ~ 1.0, potassium chloride 0.05 ~ 0.15, beet alkali hydrochlorate 0.02 ~ 0.08, diammonium hydrogen phosphate 0.01 ~ 0.07, cobalt chloride 0.0001 ~ 0.0008, nickel sulfate 0.0001 ~ 0.0008, precipitated calcium carbonate 0.1 ~ 0.6, soya-bean oil 1 ~ 4, remaining is water.
Used as a preferred embodiment, by weight percentage, fermentating formula mainly includes following components：Corn flour 1.3, fibroin powder 0.6, seitan powder 1.0, cottonseed meal 0.5, potassium chloride 0.1, beet alkali hydrochlorate 0.05, diammonium hydrogen phosphate 0.04, cobalt chloride 0.0004, nickel sulfate 0.0004, precipitated calcium carbonate 0.1, soya-bean oil 1.5, remaining is water.
Used as another preferred embodiment, by weight percentage, fermentating formula mainly includes following components：Corn flour 1.1, fibroin powder 0.8, seitan powder 1.2, cottonseed meal 0.8, potassium chloride 0.15, beet alkali hydrochlorate 0.06, diammonium hydrogen phosphate 0.05, cobalt chloride 0.0005, nickel sulfate 0.0005, precipitated calcium carbonate 0.2, soya-bean oil 2.0, remaining is water.
Realize effect：
（1）New formula does not contain fish meal, reduces impact of the quality of fishmeal to zymotic fluid quality and ferment effect, improves the stability of production；
（2）New formula substitutes fish meal with lower-cost fibroin powder, effectively reduces production cost.
Specific embodiment
Below by way of specific embodiment, the present invention is further described; but this is not limitation of the present invention, those skilled in the art's basic thought of the invention, various modifications may be made or improves; but without departing from the basic thought of the present invention, in the scope of the present invention.
Embodiment 1
A kind of tylosin fermentating formula, by weight percentage, the formula mainly includes following components：Corn flour 0.8, fibroin powder 0.5, seitan powder 0.5, cottonseed meal 0.1, potassium chloride 0.05, beet alkali hydrochlorate 0.02, diammonium hydrogen phosphate 0.01, cobalt chloride 0.0001, nickel sulfate 0.0001, precipitated calcium carbonate 0.1, soya-bean oil 1, remaining is water.
Embodiment 2
A kind of tylosin fermentating formula, by weight percentage, the formula mainly includes following components：Corn flour 2.0, fibroin powder 1.8, seitan powder 1.5, cottonseed meal 1.0, potassium chloride 0.15, beet alkali hydrochlorate 0.08, diammonium hydrogen phosphate 0.07, cobalt chloride 0.0008, nickel sulfate 0.0008, precipitated calcium carbonate 0.6, soya-bean oil 4, remaining is water.
Embodiment 3
A kind of tylosin fermentating formula, by weight percentage, the formula mainly includes following components：Corn flour 1.3, fibroin powder 0.6, seitan powder 1.0, cottonseed meal 0.5, potassium chloride 0.1, beet alkali hydrochlorate 0.05, diammonium hydrogen phosphate 0.04, cobalt chloride 0.0004, nickel sulfate 0.0004, precipitated calcium carbonate 0.1, soya-bean oil 1.5, remaining is water.
Embodiment 4
A kind of tylosin fermentating formula, by weight percentage, the formula mainly includes following components：Corn flour 1.1, fibroin powder 0.8, seitan powder 1.2, cottonseed meal 0.8, potassium chloride 0.15, beet alkali hydrochlorate 0.06, diammonium hydrogen phosphate 0.05, cobalt chloride 0.0005, nickel sulfate 0.0005, precipitated calcium carbonate 0.2, soya-bean oil 2.0, remaining is water.
The present invention substitutes fish meal using lower-cost fibroin powder, effectively reduces production cost；And newly formula does not contain fish meal, reduces impact of the quality of fishmeal to zymotic fluid quality and ferment effect, improves the stability of production.By engineer testing and actual production, as a result show that the zymotic fluid of tylosin puts tank chemical titer and brings up to 13000u/ml or so by original 11000u/ml or so, and component A content also brings up to 93% or so by original 85% or so.
Claims (3)
1. a kind of tylosin fermentating formula, it is characterised in that by weight percentage, the formula mainly includes following components：Corn flour 0.8 ~ 2.0, fibroin powder 0.5 ~ 1.8, seitan powder 0.5 ~ 1.5, cottonseed meal 0.1 ~ 1.0, potassium chloride 0.05 ~ 0.15, beet alkali hydrochlorate 0.02 ~ 0.08, diammonium hydrogen phosphate 0.01 ~ 0.07, cobalt chloride 0.0001 ~ 0.0008, nickel sulfate 0.0001 ~ 0.0008, precipitated calcium carbonate 0.1 ~ 0.6, soya-bean oil 1 ~ 4, remaining is water.
2. a kind of tylosin fermentating formula according to claim 1, by weight percentage, fermentating formula mainly includes following components：Corn flour 1.3, fibroin powder 0.6, seitan powder 1.0, cottonseed meal 0.5, potassium chloride 0.1, beet alkali hydrochlorate 0.05, diammonium hydrogen phosphate 0.04, cobalt chloride 0.0004, nickel sulfate 0.0004, precipitated calcium carbonate 0.1, soya-bean oil 1.5, remaining is water.
3. a kind of tylosin fermentating formula according to claim 2, by weight percentage, fermentating formula mainly includes following components：Corn flour 1.1, fibroin powder 0.8, seitan powder 1.2, cottonseed meal 0.8, potassium chloride 0.15, beet alkali hydrochlorate 0.06, diammonium hydrogen phosphate 0.05, cobalt chloride 0.0005, nickel sulfate 0.0005, precipitated calcium carbonate 0.2, soya-bean oil 2.0, remaining is water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510659604.1A CN106591402A (en) | 2015-10-14 | 2015-10-14 | Tylosin fermentation formula |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510659604.1A CN106591402A (en) | 2015-10-14 | 2015-10-14 | Tylosin fermentation formula |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106591402A true CN106591402A (en) | 2017-04-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510659604.1A Pending CN106591402A (en) | 2015-10-14 | 2015-10-14 | Tylosin fermentation formula |
Country Status (1)
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| CN (1) | CN106591402A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108315376A (en) * | 2018-04-19 | 2018-07-24 | 齐鲁制药（内蒙古）有限公司 | A kind of fermented nutritive liquid and fermentation process improving tylosin broth quality |
| CN112779306A (en) * | 2021-01-26 | 2021-05-11 | 浙江普洛生物科技有限公司 | Method for screening optimal proportion of calcium carbonate from fermentation liquor and application thereof |
-
2015
- 2015-10-14 CN CN201510659604.1A patent/CN106591402A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108315376A (en) * | 2018-04-19 | 2018-07-24 | 齐鲁制药（内蒙古）有限公司 | A kind of fermented nutritive liquid and fermentation process improving tylosin broth quality |
| CN112779306A (en) * | 2021-01-26 | 2021-05-11 | 浙江普洛生物科技有限公司 | Method for screening optimal proportion of calcium carbonate from fermentation liquor and application thereof |
| CN112779306B (en) * | 2021-01-26 | 2022-05-27 | 安徽普洛生物科技有限公司 | Method for screening optimal proportion of calcium carbonate from fermentation liquor and application thereof |
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| PB01 | Publication | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170426 |
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| WD01 | Invention patent application deemed withdrawn after publication |