CN106588839A - Preparing method of sweet persimmon vitamin C - Google Patents
Preparing method of sweet persimmon vitamin C Download PDFInfo
- Publication number
- CN106588839A CN106588839A CN201611257832.7A CN201611257832A CN106588839A CN 106588839 A CN106588839 A CN 106588839A CN 201611257832 A CN201611257832 A CN 201611257832A CN 106588839 A CN106588839 A CN 106588839A
- Authority
- CN
- China
- Prior art keywords
- sweet persimmon
- vitamin
- sweet
- persimmon
- preparing method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 title claims abstract description 50
- 235000009508 confectionery Nutrition 0.000 title claims abstract description 43
- 235000011511 Diospyros Nutrition 0.000 title claims abstract description 41
- 244000236655 Diospyros kaki Species 0.000 title claims abstract description 41
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 title claims abstract description 25
- 229930003268 Vitamin C Natural products 0.000 title claims abstract description 25
- 235000019154 vitamin C Nutrition 0.000 title claims abstract description 25
- 239000011718 vitamin C Substances 0.000 title claims abstract description 25
- 238000000034 method Methods 0.000 title abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 15
- 238000001914 filtration Methods 0.000 claims abstract description 11
- 239000011347 resin Substances 0.000 claims abstract description 8
- 229920005989 resin Polymers 0.000 claims abstract description 8
- 239000003480 eluent Substances 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 238000003756 stirring Methods 0.000 claims abstract description 7
- 238000000605 extraction Methods 0.000 claims abstract description 5
- 239000000706 filtrate Substances 0.000 claims description 9
- 239000012043 crude product Substances 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- 238000010828 elution Methods 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 235000013305 food Nutrition 0.000 abstract description 5
- 239000003814 drug Substances 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 150000001413 amino acids Chemical class 0.000 abstract description 2
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 238000005516 engineering process Methods 0.000 description 4
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 229930003944 flavone Natural products 0.000 description 3
- 235000011949 flavones Nutrition 0.000 description 3
- 238000000265 homogenisation Methods 0.000 description 3
- 238000004062 sedimentation Methods 0.000 description 3
- 239000006228 supernatant Substances 0.000 description 3
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000003544 deproteinization Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000000703 high-speed centrifugation Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/44—Ebenaceae (Ebony family), e.g. persimmon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a preparing method of sweet persimmon vitamin C. The preparing method specifically comprises three steps of extraction, enrichment and refinement. The preparing method comprises the specific steps of cutting up fresh leaves of the sweet persimmon, adding cold water, homogenizing the pulp, conducting filtration, adding active carbon into the filter liquor, conducting stirring and mixed suspension, conducting filtration through a high-speed settling centrifugal machine, using MCI GEL resin (75-150 micrometers) to adsorb the filter liquor, using water to elute the adsorbed liquor, collecting the eluent, conducting concentration, spraying and drying, and obtaining the sweet persimmon vitamin C. The vitamin C from natural sources prepared from the fresh leaves of the sweet permission is simple to operate and suitable for industrialized production, wherein the sweet persimmon vitamin C is rich in active components rich of sweet persimmon amino acid and the like, has a good antioxidant activity, and is a good raw material of medicine, food and health care products.
Description
Technical field
The invention belongs to medicine and food technology field, and in particular to it is a kind of from sweet persimmon fresh leaf prepare sweet persimmon vitamin C and
Its preparation method.
Background technology
The sweet persimmon leaf vitamin C of natural origin has various physiologically actives and supplementary function.Vitamin C property is not
Stable, traditional extraction is easy to decompose in preparing, and the present invention adopts low-temperature homogenate technology so as to maximum in process of production to protect
Stay, and by the technique enrichment such as decolouring, deproteinization, de- flavone, it is refined improve Vitamin C content, the method can be continuous
Production, it is simple and easy to operate.Sweet persimmon vitamin C can be used for medicine, food and cosmetic field, with huge economic benefit.
The content of the invention
It is an object of the invention to provide a kind of sweet persimmon vitamin C and preparation method thereof.
The present invention is realized by the following method：Described sweet persimmon vitamin C preparation method is that, with sweet persimmon leaf as raw material, Jing is carried
Take, be enriched with, be refining to obtain, specifically with sweet persimmon leaf as raw material, extracted, enrichment, purification step are obtained, and are specifically included：
A, extraction：Sweet persimmon fresh leaf is taken, is shredded, add 2 ~ 4 times of cold water, the temperature of cold water is 0 ~ 7 DEG C, and homogenate is filtered, and must be extracted
Liquid；
B, enrichment：By said extracted liquid, add 3% ~ 6% activated carbon, stirring to be suspended, high speed settling formula centrifugal filtration, filtrate with 75 ~
150 μm of MCI GEL resin absorptioies, with 1 times of column volume water elution, collect eluent, and concentration is spray-dried, and obtains sweet persimmon dimension life
Plain C crude products.
The beneficial effects of the present invention is：
The present invention prepares natural origin vitamin C and is applied to the fields such as medicine, food with sweet persimmon leaf as raw material, easy to operate；System
Using the skill such as fresh goods freezing homogenate, activated carbon decolorizing, high speed centrifugation deproteinization, resin de- flavone, spray drying during standby
The removal of impurity is gone in art combination, vitamin C is extracted to greatest extent in preparation process and is kept stable, also containing aminoacid, saccharide
It is the good raw material for preparing health product, food and Related product flavor additives useful Deng natural nutrient beneficiating ingredient.Meanwhile, this
Technique can also prepare the compositions such as sweet persimmon leaf flavone, and resource comprehensive recycling is carried out to greatest extent.
Specific embodiment
To make those skilled in the art understand the production technology and technique effect of the present invention in detail, below specifically producing
Being further described application and the technique effect of the present invention, following examples are the description of the invention rather than restriction to example.
A kind of ascorbic preparation method of sweet persimmon, is that, with sweet persimmon leaf as raw material, extracted, enrichment, purification step are obtained,
Specifically include：
A, extraction：Sweet persimmon fresh leaf is taken, is shredded, add 2 ~ 4 times of cold water, the temperature of cold water is 0 ~ 7 DEG C, and homogenate is filtered, and must be extracted
Liquid；
B, enrichment：By said extracted liquid, add 3% ~ 6% activated carbon, stirring to be suspended, high speed settling formula centrifugal filtration, filtrate with 75 ~
150 μm of MCI GEL resin absorptioies, with 1 times of column volume water elution, collect eluent, and concentration is spray-dried, and obtains sweet persimmon dimension life
Plain C crude products.
Vitamin C content is no less than 20% in sweet persimmon vitamin C crude product.
Embodiment 1：
The kg of sweet persimmon fresh leaf 10 is taken, is shredded, add 20 kilograms of cold water（0℃）, high-speed homogenization 20 minutes, filtration, addition in filtrate
0.5 kilogram of activated carbon, stirs 10 minutes, takes supernatant centrifugal filtration（High speed sedimentation type centrifuge）, filtrate uses MCI GEL（75~
150 μm）Resin（10kg）Absorption, with 8.5 kilograms of water elutions（1 times of column volume）, eluent is collected, concentration is spray-dried, obtains
821g sweet persimmon vitamin C crude products（Sweet persimmon Vitamin C content 23%）.
Embodiment 2：
The kg of sweet persimmon fresh leaf 15 is taken, is shredded, add 45 kilograms of cold water（0℃）, high-speed homogenization 20 minutes, filtration, addition in filtrate
0.9 kilogram of activated carbon, stirs 10 minutes, takes supernatant centrifugal filtration（High speed sedimentation type centrifuge）, filtrate uses MCI GEL（75~
150 μm）Resin（10kg）Absorption, with 8.5 kilograms of water elutions（1 times of column volume）, eluent is collected, concentration is spray-dried, obtains
952g sweet persimmon vitamin C crude products（Sweet persimmon Vitamin C content 21.2%）.
Embodiment 3：
The kg of sweet persimmon fresh leaf 8 is taken, is shredded, add 32 kilograms of cold water（0℃）, high-speed homogenization 20 minutes, filtration, addition in filtrate
0.45 kilogram of activated carbon, stirs 10 minutes, takes supernatant centrifugal filtration（High speed sedimentation type centrifuge）, filtrate uses MCI GEL（75
~150 μm）Resin（10kg）Absorption, with 8.5 kilograms of water elutions（1 times of column volume）, eluent is collected, concentration is spray-dried, obtains
659g sweet persimmon vitamin C crude products（Sweet persimmon Vitamin C content 20.3%）.
Embodiment 4：
It is prepared by sweet persimmon vitamin C compacting confection
300g sweet persimmon vitamin Cs in Example 1, add citric acid 9g, sucrose 591g, appropriate Fructus Citri Limoniae quintessence oil, mix, and use
75% ethanol is pelletized, and is dried, and granulate, tabletting obtains 1650.
Claims (2)
1. the ascorbic preparation method of a kind of sweet persimmon, it is characterised in that be extracted, enrichment, refined step with sweet persimmon leaf as raw material
Suddenly obtain, specifically include：
A, extraction：Sweet persimmon fresh leaf is taken, is shredded, add 2 ~ 4 times of cold water, the temperature of cold water is（0~7℃）, it is homogenized, filter, must extract
Liquid；
B, enrichment：By said extracted liquid, add 3% ~ 6% activated carbon, stirring to be suspended, high speed settling formula centrifugal filtration, filtrate with 75 ~
150 μm of MCI GEL resin absorptioies, with 1 times of column volume water elution, collect eluent, and concentration is spray-dried, and obtains sweet persimmon dimension life
Plain C crude products.
2. a kind of ascorbic preparation method of sweet persimmon according to claim 1, it is characterised in that sweet persimmon vitamin C crude product
Middle Vitamin C content is no less than 20%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611257832.7A CN106588839A (en) | 2016-12-30 | 2016-12-30 | Preparing method of sweet persimmon vitamin C |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611257832.7A CN106588839A (en) | 2016-12-30 | 2016-12-30 | Preparing method of sweet persimmon vitamin C |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106588839A true CN106588839A (en) | 2017-04-26 |
Family
ID=58581575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611257832.7A Pending CN106588839A (en) | 2016-12-30 | 2016-12-30 | Preparing method of sweet persimmon vitamin C |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106588839A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998024777A1 (en) * | 1996-12-01 | 1998-06-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A process for recovery of ascorbic acid |
| CN103284148A (en) * | 2013-05-20 | 2013-09-11 | 国家林业局泡桐研究开发中心 | Processing method of persimmon leaf concentrated powder rich in natural vitamin C |
| CN105175369A (en) * | 2015-10-23 | 2015-12-23 | 大连民族大学 | Extraction method for vitamin C in actinidia arguta |
-
2016
- 2016-12-30 CN CN201611257832.7A patent/CN106588839A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998024777A1 (en) * | 1996-12-01 | 1998-06-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A process for recovery of ascorbic acid |
| CN103284148A (en) * | 2013-05-20 | 2013-09-11 | 国家林业局泡桐研究开发中心 | Processing method of persimmon leaf concentrated powder rich in natural vitamin C |
| CN105175369A (en) * | 2015-10-23 | 2015-12-23 | 大连民族大学 | Extraction method for vitamin C in actinidia arguta |
Non-Patent Citations (4)
| Title |
|---|
| C. G. VINSON ET AL: "Vitamin C Content of Persimmon Leaves and Fruits", 《SCIENCE》 * |
| 危建新等: "柿叶维生素C贮藏保存方法的研究", 《中南林学院学报》 * |
| 李凌主编: "《生物化学与分子生物学实验指导》", 31 August 2015, 人民军医出版社 * |
| 缪勇等主编: "《中草药植物提取与深加工新技术实用手册》", 31 October 2004, 天津电子出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111000760B (en) | Method for preparing cosmetic base oil by using peony essential oil and seed oil | |
| CN103497830A (en) | High-quality wheat germ oil and subcritical preparation method thereof | |
| CN103494862B (en) | Method for extracting olive polyphenol from olive processing waste liquor | |
| CN111603500B (en) | Semen cassiae extract and process technology for comprehensively developing and utilizing semen cassiae | |
| CN110655453A (en) | Extraction and separation method of hypocannabidiol | |
| CN106589010A (en) | Method for simultaneously producing L-arabinose and D-galactose | |
| JP2017520616A (en) | Extraction method of chlorogenic acid from Tochu leaves | |
| CN103396891A (en) | Method for extracting essential oil by taking jackfruit peel as raw material | |
| CN104086467B (en) | A kind of solvent extraction and molecularly distilled is utilized to combine the method preparing raphanin | |
| CN108031444A (en) | A kind of method that high-efficiency adsorbent is prepared using olive pomace fiber | |
| CN107286264A (en) | The deep working method of Chinese date nutrient material separation | |
| CN111117773A (en) | Method for separating nervonic acid from garlic oil and application thereof | |
| CN110878010A (en) | Extraction and separation method of cannabigerol | |
| CN104366332B (en) | A kind of deep working method of chilli seed | |
| CN113318134A (en) | Extraction method and application of Korean pine needle polyphenol compounds | |
| CN104606276B (en) | A method of extracting small molecule persimmon leaf flavone from persimmon leaf | |
| CN101628857B (en) | Production technique for extracting resveratrol from giant knotweed | |
| CN104744601A (en) | Method for extracting and purifying fleurotus ferulae polysaccharide | |
| CN109021042B (en) | Method for extracting high-purity oleuropein from olive leaves | |
| CN106588839A (en) | Preparing method of sweet persimmon vitamin C | |
| CN104311616A (en) | Method for extracting high-purity esculine and fraxin from Cortex Fraxini | |
| CN103420969A (en) | Method for extracting anthocyanidin in grape juice | |
| CN103819572A (en) | Extraction technology for production of polysaccharide from mulberry leaf | |
| CN102757472B (en) | Method for purifying beta-sitosterol from cornel kernels | |
| CN104745332A (en) | Condensed soap prepared by raw material of Yunnan big leaf species tea-seed oil |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170426 |