CN106580239B - A kind of angiocarpy three-dimensional optical coherent video system - Google Patents
A kind of angiocarpy three-dimensional optical coherent video system Download PDFInfo
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Abstract
The present invention provides a kind of cardiovascular three-dimensional optical coherent video system, and the angiocarpy three-dimensional optical coherent video system includes sequentially connected probe unit, probe interface unit, optical signal processing unit, digital signal processing unit and display；The probe unit includes fibre-optical probe, and the fibre-optical probe is used for the sample signal of the movement acquisition blood vessel according to the probe interface unit, and the sample signal is sent to the optical signal processing unit by the probe interface unit；The optical signal processing unit to the sample signal for being handled to obtain picture frame；The digital signal processing unit includes data converter and data corrector；The data corrector carries out Data correction for the picture frame after converting respectively to the data converter and three-dimensionalreconstruction obtains 3-D image, and exports to the display and shown.The angiocarpy three-dimensional optical coherent video system can be improved the accuracy of three-dimensional optical coherence imaged image.
Description
Technical field
The present invention relates to cardiovascular based endoscopic imaging technical field more particularly to a kind of cardiovascular three-dimensional optical coherent video systems
System.
Background technique
Optical coherence image technology is a kind of imaging technique that last decade develops rapidly, it is dry using weak coherent light
The light that light source issues is divided into two beams by the basic principle of interferometer, a branch of to be emitted to tested tissue, is also sample arm, another beam
It is emitted to referring to reflective mirror, is also reference arm, then the two-beam letter from tested tissue and from reference mirror reflection back
Number superposition, interference, the image grayscale of different powers is finally shown with the difference of tested tissue according to optical signal, thus to group
Knit interior be imaged.
Optical coherence image can be divided into Time Domain Optical coherent video according to technical principle and domain optical coherence image two is big
Class.Domain optical coherence image due to it with high-resolution, image taking speed is fast, non-invasively advantages such as imaging in tissue, by
It is widely used in the imaging of the organs such as ophthalmology, alimentary canal, angiocarpy.In comparison, cardiovascular optical coherence image system is the most
The cardiovascular optical coherence image documentation equipment of complexity, complete set needs to integrate: light source, optical splitter, optical interdferometer, reference arm,
Probe interface unit (probe interface unit, PIU), conduit, blood flushing liquor injection device, fibre-optical probe, high speed
The resources such as data collector, signal processor, image processing software.The basic principle of cardiovascular optical coherence image scan imaging
It is: drives the fibre-optical probe of front end to do tomoscan in the blood vessels by PIU high speed rotation and pullback motion, and by bourdon tube
Imaging.3D angiocarpy optical coherence image has huge potential advantages, 3D painstaking effort lightpipe optics phase compared with 2D optical coherence image
Dry image intuitively can provide the space three-dimensional structure information of blood vessel for doctor, doctor can be helped to better understand thrombus
The adherent situation of spatial shape, bracket assesses bifurcated lesions, instructs to expand after bracket, instruct thrombectomby etc..
But 3D angiocarpy optical coherence image is absolutely not simply to arrive 2D optical coherence image sequence image stack
It is rendered to 3D picture together, because reconstruct can have error, the serious understanding that can also mislead doctor in this way.In real work
In, since the frictional force between bourdon tube and conduit can shake when rotating at high speed, the three-dimensional optical for causing actual acquisition to arrive
Coherent video image can be axially formed it is rotary shifted, in this way if directly to sequence image carry out three-dimensionalreconstruction, in three-dimensional space
Between in be exist dislocation, therefore, such result be for clinical analysis it is inaccurate, it is serious will lead to mistake examine
Disconnected result.
Summary of the invention
To solve the above-mentioned problems, it the invention proposes a kind of cardiovascular three-dimensional optical coherent video system, can be improved
The accuracy of three-dimensional optical coherence imaged image.
It is proposed by the present invention the specific technical proposal is: providing a kind of cardiovascular three-dimensional optical coherent video system, the heart
Blood vessel three-dimensional optical coherent video system includes sequentially connected probe unit, probe interface unit, optical signal processing unit, number
Word signal processing unit and display；The probe unit includes fibre-optical probe, and the fibre-optical probe is used for according to the probe
The sample signal of the movement acquisition blood vessel of interface unit, and the sample signal is sent to institute by the probe interface unit
State optical signal processing unit；The optical signal processing unit to the sample signal for being handled to obtain picture frame；It is described
Digital signal processing unit includes data converter and data corrector；The data corrector is for respectively turning the data
Picture frame after parallel operation conversion carries out Data correction and three-dimensionalreconstruction obtains 3-D image, and exports to the display and shown
Show.
Further, the data corrector includes reference points detection unit, image correction unit and three-dimensionalreconstruction unit；
The reference points detection unit is used to obtain the position mark point of the picture frame after the data converter conversion, described image school
Positive unit is used to carry out rotation transformation to the picture frame after data converter conversion according to the position mark point to obtain school
Picture frame after standard, the three-dimensionalreconstruction unit are used to carry out three-dimensionalreconstruction to the picture frame after the calibration to obtain three-dimensional figure
Picture.
Further, the digital signal processing unit further includes feedback controller, and the feedback controller is used for basis
The luminance information and gradient information of picture frame after the data converter conversion control the movement shape of the probe interface unit
State；The feedback controller includes starting module of pulling back；It is described pull back starting module for detect vessel lumen whether rinse it is dry
Only the probe interface unit starting pullback motion is controlled and when the vessel lumen is rinsed well.
Further, the starting module of pulling back includes computing unit, judging unit and pulls back and begin to respond to unit, described
Computing unit is used to calculate the equal of brightness of the picture frame in scheduled flushing detection zone after the data converter conversion
Value and variance；The judging unit is triggered for judging whether the mean value and the variance meet trigger condition, and meeting
It is sent back when condition and pulls open beginning trigger signal；Described pull back begins to respond to unit and starts trigger signal control for pulling back according to
Make the probe interface unit starting pullback motion.
Further, the feedback controller includes stopping modular of pulling back, and the stopping modular of pulling back is described for detecting
Whether fibre-optical probe, which moves to predetermined position and control the probe when the fibre-optical probe moves to the predetermined position, connects
Mouth unit stops pullback motion.
Further, the stopping modular of pulling back includes the second computing unit, second judgment unit and stopping response of pulling back
Unit, second computing unit are used to calculate the mean value and most of the picture frame maximum brightness value after data converter conversion
The mean and variance of big gradient value；The second judgment unit is used to judge that the mean value of the maximum brightness value and the maximum to be terraced
Whether the mean and variance of angle value meets the second trigger condition, and stopping triggering letter of pulling back is sent when meeting the second trigger condition
Number；Described pull back stops response unit and stops the trigger signal control probe interface unit for pulling back according to and stop back
Roping is dynamic.
Further, the probe unit further includes conduit, optical fiber, transparent outer sleeve and bourdon tube, the optical fiber, spring
Pipe and fibre-optical probe are located in the conduit, and the conduit includes being provided with flushing on the body outside outside internal portion and body
Liquid inlet, the internal portion are additionally provided with flushing liquor outlet far from one end outside the body；The fibre-optical probe passes through institute
It states optical fiber to connect with the probe interface unit, the bourdon tube is sheathed on the optical fiber, and the transparent outer sleeve is coated at
In the internal portion and between the fibre-optical probe and the body outside.
Further, the probe interface unit includes motor, and the motor is connect with the bourdon tube.
Further, the optical signal processing unit includes light source, interferometer and point being separately connected with the interferometer
Light device, detector and reflective mirror, the light source are connect with the optical splitter, and the interferometer is connect with the probe interface unit
The detector is connect with the data signal processing unit.
Angiocarpy three-dimensional optical coherent video system proposed by the present invention has the advantage that
(1) the cardiovascular three-dimensional optical coherent video system includes data corrector, and data corrector can be right respectively
Picture frame after data converter conversion carries out Data correction and three-dimensionalreconstruction obtains 3-D image；
(2) the cardiovascular three-dimensional optical coherent video system includes feedback controller, can control the probe and connect
The motion state of mouth unit；The feedback controller includes starting module of pulling back, and starting module of pulling back is able to detect vessel lumen
Whether rinse well and controls the probe interface unit starting pullback motion in the case where vessel lumen is rinsed well；
(3) feedback controller further includes stopping modular of pulling back, and the stopping modular of pulling back is able to detect the optical fiber
Whether probe moves to the position of the transparent outer sleeve and moves to the position of the transparent outer sleeve in the fibre-optical probe
When control the probe interface unit and stop pullback motion.
Detailed description of the invention
What is carried out in conjunction with the accompanying drawings is described below, above and other aspect, features and advantages of the embodiment of the present invention
It will become clearer, in attached drawing:
Fig. 1 is the structural schematic diagram of cardiovascular three-dimensional optical coherent video system；
Fig. 2 is the structural schematic diagram of feedback controller in Fig. 1；
Fig. 3 is the structural schematic diagram of starting module of pulling back in Fig. 2；
Fig. 4 is the schematic diagram for rinsing detection zone；
Fig. 5 is the structural schematic diagram of stopping modular of pulling back in Fig. 2；
Fig. 6 is coordinate transform schematic diagram；
Fig. 7 is the structural schematic diagram of data corrector in Fig. 1；
Fig. 8 is according to the corrected process schematic of position mark point；
Fig. 9 is the three-dimensionalreconstruction interface schematic diagram in the present embodiment；
Figure 10 is the flow diagram of the imaging method of cardiovascular three-dimensional optical coherent video system.
Specific embodiment
Hereinafter, with reference to the accompanying drawings to detailed description of the present invention embodiment.However, it is possible to come in many different forms real
The present invention is applied, and the present invention should not be construed as limited to the specific embodiment illustrated here.On the contrary, providing these implementations
Example is in order to explain the principle of the present invention and its practical application, to make others skilled in the art it will be appreciated that the present invention
Various embodiments and be suitable for the various modifications of specific intended application.
Referring to Fig.1, cardiovascular three-dimensional optical coherent video system provided in this embodiment, for obtaining three-dimensional optics phase
Dry imaged image, wherein three-dimensional optical coherence imaged image is made of multiple images frame.Cardiovascular three-dimensional optical coherent video
System include sequentially connected probe unit 1, probe interface unit 2, optical signal processing unit 3, digital signal processing unit 4 and
Display 5.Probe unit 1 includes fibre-optical probe 11, and fibre-optical probe 11 is used to acquire blood vessel according to the movement of probe interface unit 2
Sample signal and sample signal is sent to optical signal processing unit 3 by probe interface unit 2, probe interface unit here
2 movement includes rotation and pulls back, and the sample signal of blood vessel includes vascular wall and endovascular signal.Optical signal processing unit 3
For being handled sample signal to obtain picture frame.Specifically, digital signal processing unit 4 includes feedback controller 41, number
According to corrector 42 and data converter 44, feedback controller 41 is used for the brightness according to the picture frame after the conversion of data converter 44
The motion state of value and gradient value control probe interface unit 2, the motion state of probe interface unit 2 includes that starting is pulled back here
Movement and stop two states of pullback motion, data corrector 42 for respectively to data converter 44 convert after picture frame into
Row Data correction and three-dimensionalreconstruction obtain 3-D image, and display 5 is for showing 3-D image.Three-dimensional optical coherence
Imaged image is made of the mapping of multiple images frame interpolation, the three-dimensional optical coherence imaged image after display display mapping.
Probe unit 1 further includes conduit 12, optical fiber 13, transparent outer sleeve 14 and bourdon tube 15, optical fiber 13, bourdon tube 15 and
Fibre-optical probe 11 is located in conduit 12.Conduit 12 is connect with probe interface unit 2, and conduit 12 includes body outside internal portion and body
Inside is for being inserted into intracorporal blood vessel.Flushing liquor inlet 12a is provided on body outside, internal portion is far from one end outside body
It is additionally provided with flushing liquor outlet 12b, flushing liquor is injected into conduit 12 simultaneously by flushing liquor injection device from flushing liquor inlet 12a
It is discharged from flushing liquor outlet 12b.Fibre-optical probe 11 is located at internal portion far from one end outside body, passes through optical fiber 13 and probe
Interface unit 2 connects, and bourdon tube 15 is sheathed on optical fiber 13, and transparent outer sleeve 14 is coated in internal portion and is located at fibre-optical probe
Between 11 and body outside.
Probe interface unit 2 includes motor (not shown), and motor is connect with bourdon tube 15, and motor is used for driving spring pipe 15
It rotates and Return spring pipe 15, bourdon tube 15 occurs elastic deformation and be tightly sheathed on optical fiber 13 and by between optical fiber 13
Frictional force drives optical fiber 13 and fibre-optical probe 11 rotates together and pull back optical fiber 13 and fibre-optical probe 11, to make fibre-optical probe 11
It is moved in 12 inside spin of conduit, forms spiral three-dimensional scanning.
Optical signal processing unit 3 includes light source 31, optical splitter 32, detector 33, interferometer 34 and reflective mirror 35.Light source 31
The light beam of sending is divided into two bundles duplicate light after the effect of optical splitter 32, and light beam is emitted to reflective mirror by interferometer 34
35, referred to as reference arm, a branch of to be sent to probe interface unit 2 by interferometer 34, probe interface unit 2 again passes through the light beam
Optical fiber 13, which is transmitted to fibre-optical probe 11 and is concurrently incident upon internal blood vessel, to be detected, referred to as sample arm.Light in reference arm is through reflective
The reference light that mirror 35 is formed after reflecting is incident on interferometer 34, is formed after the reflection of light menses inside pipe wall and scattering in sample arm
Sample signal is received by fibre-optical probe 11 and is back to interferometer 34.Interferometer 34 is overlapped reference signal and sample signal
Generate the optical signal after optical interference is interfered, wherein different tissue profiles forms the letter of the light after the interference of different powers
Number, the power of optical signal can reflect endovascular design feature.Detector 33 is used to detect the optical signal after interfering and by its turn
It is changed to corresponding electric signal.
Digital signal processing unit 4 further includes data collector 43.Data collector 43 is connect with detector 33, is used for
It receives the electric signal and the electric signal is converted into the corresponding digital signal of picture frame, data converter 44 is for receiving institute
It states digital signal and the digital signal is converted into cartesian coordinate space from polar coordinate space.Wherein, in the present embodiment
Data converter 44 can realization in many different forms, including but not limited to processor (CPU), graphics processor (GPU),
Programmable gate array (FPGA), microprocessor (such as ARM), digital signal processor (DSP) device or their any combination.
It in optical coherence video imaging, generally requires and vessel inner blood is rinsed, otherwise blood has light relatively strong
Absorption and scattering process, influence image quality.Before triggering cardiovascular optical coherence image scan, clinician's injecting blood
Flushing liquor, and observe optical coherence video imaging preview screen when confirmation blood is rinsed well, triggers PIU manually and pulls back instruction
Carry out three-dimensional imaging.Very big inconvenience is brought to clinical practice operation however, manually triggering PIU and pulling back, pulls back and triggers too early often
Vessel inner blood is not rinsed well, and image quality is caused to be deteriorated, and is unable to satisfy clinical diagnosis demand；It was triggered on the contrary, pulling back
Evening, the blood flushing liquor that patient injection will be given excessive bring unnecessary side effect to patient.
In addition, existing angiocarpy optical coherence image is often by one fixed distance of pulling back of setting at present, i.e.,
PIU triggering after certain distance of pulling back stops pulling back.However, being collected when fibre-optical probe is withdrawn into transparent outer sleeve
Data be invalid, the data in transparent outer sleeve, not only carried out unnecessary money to Data Post, data tape
Source waste, after three-dimensional rendering, also can cause to judge by accident to diagnosis.
Referring to Fig. 2, the feedback controller 41 in the present embodiment includes pull back starting module 410 and stopping modular 411 of pulling back.
Starting module of pulling back 410 is used to detect whether vessel lumen to be rinsed well and control probe connects when vessel lumen is rinsed well
Mouth unit 2 starts pullback motion, and after probe interface unit 2 starts pullback motion, motor starts to pull back and driving spring pipe is pulled back
Optical fiber 13 and fibre-optical probe 11, fibre-optical probe 11 start screw in conduit 12 and start three-dimensional spiral scanning.It pulls back and stops
Only whether module 411 moves to the position of transparent outer sleeve 14 and moves in fibre-optical probe 11 for detection fiber probe 11
Probe interface unit 2 is controlled when the position of transparent outer sleeve 14 and stops pullback motion, and probe interface unit 2 stops pullback motion
Afterwards, motor stops rotating and stops driving spring pipe 15, at this point, fibre-optical probe 11 stops scanning.
Specifically, starting module of pulling back 410 includes the first computing unit 100, the first judging unit 101 referring to Fig. 3, Fig. 4
And pull back and begin to respond to unit 102, for the ease of distinguishing, the computing unit in starting module of pulling back is named as the first meter here
Unit 100 is calculated, the judging unit in starting module of pulling back is named as the first judging unit 101.First computing unit 100 is used for
Calculate the brightness I of the digital signal in the cartesian coordinate space in scheduled flushing detection zone1Mean and variance,
First threshold th is preset in one judging unit 1011And second threshold th2, the first judging unit 101 is for judging the mean value
Whether first threshold th is less than1And whether the variance is less than second threshold th2And it is less than first threshold th in the mean value1And
The variance is less than second threshold th2When send back to pull open beginning trigger signal and give back to and pull open beginning response unit 102, pull back and start to ring
Answer unit 102 for according to pulling back and start the trigger signal control starting pullback motion of probe interface unit 2, i.e., the described mean value and institute
It states variance and meets following trigger condition:
mean(I1) < th1
std(I1) < th2。
The scheduled width for rinsing detection zone is set as to 2 times (as shown in Figure 4) of conduit diameter in the present embodiment, when
So, scheduled flushing detection zone can determine according to the actual situation, here without limitation.If vessel lumen is rinsed well,
Then the mean value and variance of the brightness of annular detection zone should be smaller, therefore, when the mean value and the variance meet above two
When a condition, the first judging unit 101, which generates one and pulls back, to be started trigger signal and described pull back is started trigger signal transmission
It gives back to and pulls open beginning response unit 102, the motor begun to respond in the control probe interface unit 2 of unit 102 of pulling back starts high speed and revolves
Turn and bourdon tube 15 is driven to rotate, bourdon tube 15 occurs elastic deformation and drives optical fiber 13 by the frictional force between optical fiber 13
With fibre-optical probe 11 rotation and pull back optical fiber 13 and fibre-optical probe 11, thus make fibre-optical probe 11 12 inside spin of conduit move,
Spiral three-dimensional scanning is formed, endovascular three-dimensional spiral scan image is finally obtained.
Referring to Fig. 5, Fig. 6, stopping modular 411 of pulling back includes the second computing unit 103, second judgment unit 104 and pulls back
Stop response unit 105.Second computing unit 103 is for being converted to the digital signal in the cartesian coordinate space in Fig. 6
Digital signal in polar coordinate space (ρ, θ), wherein ρ is polar diameter, and θ is polar angle.Second computing unit 103 is also used to calculate pole
The maximum brightness value I on each column of digital signal radially in coordinate spacedAnd greatest gradient value G and calculate it is all most
Big brightness value IdMean value and all greatest gradient value G mean and variance.
Third threshold value th is preset in second judgment unit 1043, the 4th threshold value th4And the 5th threshold value th5, the second judgement list
Member 104 is for judging maximum brightness value IdMean value whether be greater than third threshold value th3, greatest gradient value G mean value whether be greater than
Four threshold value th4And whether the variance of greatest gradient value is less than the 5th threshold value th5And in maximum brightness value IdMean value be greater than third threshold
Value th3, greatest gradient value G mean value be greater than the 4th threshold value th4And the variance of greatest gradient value G is less than the 5th threshold value th5When send
It pulls back and stops trigger signal and stop response unit 105 to pulling back, pulling back stops response unit 105 and control in probe interface unit 2
Motor stopping pull back fibre-optical probe 11, i.e. maximum brightness value IdMean value, the mean value of greatest gradient value G and greatest gradient value G
Variance meet following three conditions:
mean(Id) > th3
Mean (G) > th4。
Std (G) < th5
Wherein, the number in polar coordinate space is believed by using to vertical edge sensitive Prewitt boundary filter
Number handled, obtain gradient image, then detect the greatest gradient value G on each column radially, then calculate it is all most
The gradient mean value and variance of big gradient value G.As maximum brightness value IdMean value, the mean value of greatest gradient value G and greatest gradient value G
Variance simultaneously meet above three formulas when, then illustrate to include transparent outer sleeve 14 in the picture frame, i.e. fibre-optical probe 11
Scheduled position is moved to.
Data referring to Fig. 7, Fig. 8, in order to improve the accuracy of three-dimensional optical coherence imaged image, in the present embodiment
Corrector 42 includes reference points detection unit 420, image correction unit 421 and three-dimensionalreconstruction unit 422.Reference points detection unit
420 for obtaining the position mark point of the digital signal in cartesian coordinate space, especially by detection in pre-set radius area
The gray value of the digital signal in cartesian coordinate space in domain then takes maximum ash if there is multiple points meet gray threshold
Mark point of the location point corresponding to angle value as the digital signal in cartesian coordinate space.
Image correction unit 421 is used to carry out school to the digital signal in cartesian coordinate space according to position mark point
Picture frame after calibration will definitely be arrived, carries out school to the digital signal in cartesian coordinate space especially by rotational transformation matrix
Standard, rotation transformation used by the present embodiment is rotated based on picture centre, the matrix of rotation transformation are as follows:
Rotation transformation formula is as follows:
In formula, (x0, y0) be original coordinate system coordinate, (x, y) be postrotational picture frame in pixel coordinate, θ table
Show rotation angle, rotate clockwise and be positive, rotation is negative counterclockwise.As shown in figure 8, after by calibration, all images in sequence
The mark point of frame is longitudinally being based on identical direction.
Three-dimensionalreconstruction unit 422 is used to carry out three-dimensionalreconstruction to the picture frame after calibration to obtain 3-D image, specifically will
Picture frame after calibration is by three-dimensionalreconstruction algorithm, i.e., according to color mapping and opacity mapping function, by the figure after calibration
As frame is mapped to projected image plane by object plotting method.
The three-dimensionalreconstruction interface according to shown in the present embodiment is shown referring to Fig. 9, Fig. 9.It is aobvious that it comprises cardiovascular 3D
Show window, longitudinal cross-section display window, transversal cross-section display window and control panel.Through this embodiment, it can be seen that right
After Cardiovascular data calibration, three-dimensional structure can accurately reflect blood vessel and intravascular each component (such as conduit, seal wire)
Actual position.
Referring to Fig.1 0, the present embodiment additionally provides the imaging method of above-mentioned cardiovascular three-dimensional optical coherent video system, uses
In obtaining three-dimensional optical coherence imaged image, three-dimensional optical coherence imaged image is made of multiple images frame, the method
The following steps are included:
Step S1, fibre-optical probe 11 acquires the sample signal of blood vessel according to the movement of probe interface unit 2 and believes sample
Number optical signal processing unit 3 is sent to by probe interface unit 2.
Wherein, step S1 is specifically included first under the guidance of seal wire and X-ray radiography, passes through percutaneous coronary intervention
Fibre-optical probe 11 is placed in position to be scanned, flushing is then injected in flushing liquor inlet 12a by flushing liquor injection device
Liquid is rinsed the blood in vessel lumen, meanwhile, fibre-optical probe 11 acquires sample signal and will by probe interface unit 2
Sample signal is sent to optical signal processing unit 3.
Step S2, optical signal processing unit 3 is handled to obtain picture frame and picture frame is sent to number to sample signal
Word signal processing unit 4.
Step S3, digital signal processing unit 4 carries out Data correction respectively to picture frame and three-dimensionalreconstruction obtains three-dimensional figure
Picture.
Step S4, display 5 receives and shows 3-D image.
Specifically, digital signal processing unit 4 carries out Data correction respectively to picture frame in step S3 and three-dimensionalreconstruction obtains
To 3-D image the following steps are included:
Gray value of the described image frame in pre-set radius region is calculated, gray threshold and the maximum point of gray value will be met
Position mark point as described image frame；
The picture frame after rotation transformation is corrected is carried out to described image frame according to the position mark point；
Three-dimensionalreconstruction is carried out to the picture frame after the correction and obtains 3-D image.
Specifically, step S3 further includes luminance information and gradient information control of the digital signal processing unit 4 according to picture frame
The motion state of probe interface unit 2 processed；Wherein, first threshold and second threshold are preset in digital signal processing unit 4, number
Word signal processing unit 4 according to the luminance information and gradient information of picture frame control probe interface unit 2 motion state include
Following steps:
Calculate brightness I of the described image frame in scheduled flushing detection zone1Mean and variance；
Judge whether the mean value is less than first threshold th1And whether the variance is less than second threshold th2If described equal
Value is less than first threshold th1And the variance is less than second threshold th2, then control probe interface unit 2 and start pullback motion.
If the mean value is not less than first threshold th1Or the variance is not less than second threshold th2, then step S3 further include:
Described image frame is converted into the picture frame under polar coordinate system；
Calculate the maximum brightness value I of each column image of picture frame radially under the polar coordinate systemdAnd greatest gradient
Value G；
Calculate all maximum brightness value IdMean value and all greatest gradient value G mean and variance；
Judge maximum brightness value IdMean value whether be greater than third threshold value th3, greatest gradient value G mean value whether be greater than
Four threshold value th4And whether the variance of greatest gradient value G is less than the 5th threshold value th5If maximum brightness value IdMean value be greater than third threshold
Value th3, greatest gradient value G mean value be greater than the 4th threshold value th4And the variance of greatest gradient value G is less than the 5th threshold value th5, then control
Probe interface unit 2 processed stops pullback motion.
The cardiovascular three-dimensional optical coherent video system and its imaging method that the present embodiment proposes have the advantage that
(1) cardiovascular three-dimensional optical coherent video system includes data corrector 42, and data corrector 42 can be to data
Picture frame after the conversion of converter 44 carries out Data correction respectively and three-dimensionalreconstruction obtains 3-D image, improves three-dimensional optics
The accuracy of coherent video image；
(2) cardiovascular three-dimensional optical coherent video system includes feedback controller 41, can control probe interface unit 2
Motion state；Feedback controller 41 includes starting module 410 of pulling back, and starting module of pulling back 410, which is able to detect vessel lumen, is
It is no to rinse well and control the starting pullback motion of probe interface unit 2 in the case where vessel lumen is rinsed well；
(3) feedback controller 41 further includes stopping modular 411 of pulling back, and stopping modular 411 of pulling back is able to detect fibre-optical probe
Whether 11 move to the position of transparent outer sleeve 14 and control spy when fibre-optical probe 11 moves to the position of transparent outer sleeve 14
Head interface unit 2 stops pullback motion.
Although the present invention has shown and described referring to specific embodiment, it should be appreciated by those skilled in the art that:
In the case where not departing from the spirit and scope of the present invention being defined by the claims and their equivalents, can carry out herein form and
Various change in details.
Claims (7)
1. a kind of angiocarpy three-dimensional optical coherent video system, which is characterized in that connect including sequentially connected probe unit, probe
Mouth unit, optical signal processing unit, digital signal processing unit and display；The probe unit includes fibre-optical probe, described
Fibre-optical probe is used for the sample signal of the movement acquisition blood vessel according to the probe interface unit, and the sample signal is passed through
The probe interface unit is sent to the optical signal processing unit；The optical signal processing unit is used for the sample signal
It is handled to obtain picture frame；The digital signal processing unit includes data converter and data corrector；The data school
Picture frame of the positive device for after converting respectively to the data converter carries out Data correction and three-dimensionalreconstruction obtains 3-D image,
And export and shown to the display, the digital signal processing unit further includes feedback controller, the feedback control
Device is used to control the probe interface list according to the luminance information and gradient information of the picture frame after data converter conversion
The motion state of member；The feedback controller includes starting module of pulling back；The starting module of pulling back is for detecting vessel lumen
Whether rinse and control when the vessel lumen is rinsed well the probe interface unit starting pullback motion well, it is described
Starting module of pulling back includes the first computing unit, the first judging unit and pulls back and begin to respond to unit, first computing unit
For calculating the mean and variance of brightness of the picture frame after the data converter is converted in scheduled flushing detection zone；
First judging unit is for judging the mean value and whether the variance meets trigger condition, and when meeting trigger condition
It sends back and pulls open beginning trigger signal；Described pull back begins to respond to unit and starts described in trigger signal control for pulling back according to
Probe interface unit starting pullback motion.
2. angiocarpy three-dimensional optical coherent video system according to claim 1, which is characterized in that the data corrector
Including reference points detection unit, image correction unit and three-dimensionalreconstruction unit；The reference points detection unit is described for obtaining
The position mark point of picture frame after data converter conversion, described image correct unit and are used for according to the position mark point pair
Picture frame after the data converter conversion carries out the picture frame after rotation transformation is calibrated, and the three-dimensionalreconstruction unit is used
3-D image is obtained in carrying out three-dimensionalreconstruction to the picture frame after the calibration.
3. angiocarpy three-dimensional optical coherent video system according to claim 1, which is characterized in that the feedback controller
Including stopping modular of pulling back, it is described pull back stopping modular for detect the fibre-optical probe whether move to predetermined position and
The fibre-optical probe controls the probe interface unit and stops pullback motion when moving to the predetermined position.
4. angiocarpy three-dimensional optical coherent video system according to claim 3, which is characterized in that described pull back stops mould
Block includes the second computing unit, second judgment unit and pulls back and stop response unit, and second computing unit is for calculating institute
The mean value of picture frame maximum brightness value after stating data converter conversion and the mean and variance of greatest gradient value；Described second sentences
Disconnected unit is for judging whether the mean value of the maximum brightness value and the mean and variance of the greatest gradient value meet the second touching
Clockwork spring part, and send to pull back when meeting the second trigger condition and stop trigger signal；Described pull back stops response unit for root
Stop the trigger signal control probe interface unit stopping pullback motion according to described pull back.
5. angiocarpy three-dimensional optical coherent video system according to claim 1, which is characterized in that the probe unit is also
Including conduit, optical fiber, transparent outer sleeve and bourdon tube, the optical fiber, bourdon tube and fibre-optical probe are located in the conduit, described
Conduit includes flushing liquor inlet being provided on the body outside, the internal portion is far from described external outside internal portion and body
The one end in portion is additionally provided with flushing liquor outlet；The fibre-optical probe is connect by the optical fiber with the probe interface unit, institute
Bourdon tube is stated to be sheathed on the optical fiber, the transparent outer sleeve be coated in the internal portion and be located at the fibre-optical probe with
Between the body outside.
6. angiocarpy three-dimensional optical coherent video system according to claim 5, which is characterized in that the probe interface list
Member includes motor, and the motor is connect with the bourdon tube.
7. angiocarpy three-dimensional optical coherent video system according to claim 1, which is characterized in that the optical signal prosessing
Unit includes light source, interferometer and the optical splitter being separately connected with the interferometer, detector and reflective mirror, the light source and institute
Optical splitter connection is stated, the interferometer is connect with the probe interface unit, and the detector and data-signal processing are single
Member connection.
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| CN2016108162272 | 2016-09-09 | ||
| CN201610816227.2A CN106343957A (en) | 2016-09-09 | 2016-09-09 | Three dimensional OCT scan imaging system for cardiovascular applications and imaging method thereof |
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| CN201720058984.8U Withdrawn - After Issue CN207286036U (en) | 2016-09-09 | 2017-01-17 | A kind of angiocarpy three-dimensional optical coherent video system |
| CN201710036413.9A Active CN106580239B (en) | 2016-09-09 | 2017-01-17 | A kind of angiocarpy three-dimensional optical coherent video system |
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| CN201720058984.8U Withdrawn - After Issue CN207286036U (en) | 2016-09-09 | 2017-01-17 | A kind of angiocarpy three-dimensional optical coherent video system |
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| CN106343957A (en) * | 2016-09-09 | 2017-01-25 | 深圳市中科微光医疗器械技术有限公司 | Three dimensional OCT scan imaging system for cardiovascular applications and imaging method thereof |
| CN106846347B (en) * | 2017-02-15 | 2021-09-14 | 深圳市中科微光医疗器械技术有限公司 | OCT-based analysis system and analysis method before stent implantation |
| CN107518877A (en) * | 2017-08-25 | 2017-12-29 | 广州永士达医疗科技有限责任公司 | A kind of calibrating installation and method of OCT conduits |
| CN107945176B (en) * | 2017-12-15 | 2021-05-11 | 西安中科微光影像技术有限公司 | Color IVOCT imaging method |
| CN108553088B (en) * | 2018-05-11 | 2024-04-16 | 苏州阿格斯医疗技术有限公司 | OCT system |
| CN109223047B (en) * | 2018-09-19 | 2022-04-15 | 深圳开立生物医疗科技股份有限公司 | Ultrasonic instrument |
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| CN207286036U (en) * | 2016-09-09 | 2018-05-01 | 深圳市中科微光医疗器械技术有限公司 | A kind of angiocarpy three-dimensional optical coherent video system |
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| JP5523791B2 (en) * | 2008-10-27 | 2014-06-18 | 株式会社東芝 | X-ray diagnostic apparatus and image processing apparatus |
| US20140379369A1 (en) * | 2012-01-04 | 2014-12-25 | Draeger Medical Systems, Inc. | Patient Identification and Monitoring System |
| US9351698B2 (en) * | 2013-03-12 | 2016-05-31 | Lightlab Imaging, Inc. | Vascular data processing and image registration systems, methods, and apparatuses |
| US9702762B2 (en) * | 2013-03-15 | 2017-07-11 | Lightlab Imaging, Inc. | Calibration and image processing devices, methods, and systems |
| CN105792747A (en) * | 2013-11-18 | 2016-07-20 | 火山公司 | Tracking an intraluminal catheter |
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