CN106563174B - A kind of compound rhodamine oil and preparation method thereof improving female reproductive health - Google Patents
A kind of compound rhodamine oil and preparation method thereof improving female reproductive health Download PDFInfo
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- CN106563174B CN106563174B CN201610939044.XA CN201610939044A CN106563174B CN 106563174 B CN106563174 B CN 106563174B CN 201610939044 A CN201610939044 A CN 201610939044A CN 106563174 B CN106563174 B CN 106563174B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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Abstract
The invention discloses a kind of compound rhodamine oils and preparation method thereof for improving female reproductive health, belong to both sexes field of health care products.Compound rhodamine oil disclosed by the invention includes 60 parts of Rosa Damascanas, 25 parts of cinnamon essential oils and 15 parts of onion essential oils.Product of the invention does not stimulate mildly, and effect of promoting the sexual maturity is obvious, is very suitable for nursing in daily privates.In addition, product temperature of the invention is pure and fresh, fragrance is simple and elegant, has and relieves stress, loosens the mind.
Description
Technical field
The present invention relates to a kind of enriching yin, the compound rhodamine oil of promotion hormone secretion, belong to both sexes field of health care products.
Background technique
With the progress of civilized society, people put forward higher requirements for quality of life, but environmental pollution, diet dirt
Dye is but aggravating, and causes cold yin-yang impotence, the incidence of presenility excessively higher and higher.
Vagina lubrication is the important physiological performance of sexual life incipient stage, and normal vagina can keep certain and moisten
Degree, during sexual arousal is walked to orgasm, due to the accumulation of sexual excitement, vagina can generate from less to more secretion to lubricate yin
Road.These lubricating fluids are formed by diffusate and before introitus mainly from the juice in uterus, vaginal wall hyperemia
The big glandular secretion liquid in front yard.If few do not secrete even of the lubricating fluid of secretion will result in vaginal dryness, and vaginal dryness not only influences
Life quality reduces the happiness and self-confidence of women, can also weaken the natural defence capability of vagina.It is reported that being more than
30% women is with diseases such as vaginitis, cervicitis, cervical erosion, pudendal pruritus.
" water-soluble human body lubricants " disclosed in CN1544100A, then water removal and glycerol, propylene glycol, hydroxyethyl cellulose increase
(methylparaben, ethylparaben, propylben, chlorhexidine gluconate, bi-imidazolidinyl urea are prevented for stick, preservative
Rotten agent) and pH adjusting agent (acetic acid and citric acid) is outside, it is main also added with the water-soluble aloe powder using nanofiltration membrane separation concentration
If utilizing its antiinflammation.It is the haptens because in asparagus juice and why with this aloe powder and without asparagus juice
Substance can cause allergic reaction and Aloe original juice in moisture content can not have excellent lubricant effect.And above-mentioned chemistry closes
Also there is certain stimulation to mucous membrane at preservative.Therefore in two sexual lifves, women need it is a kind of have promote hormone cover secretion,
The daily necessity without side-effects of antibacterial anti-inflammatory and maintenance health-care effect.
Summary of the invention
Aiming at the problem that being referred in above-mentioned background technique, the present invention provide it is a kind of for daily female reproductive health nursing
Compound rhodamine oil.Product of the invention mildly can promote estrogen to secrete, and have certain biocidal efficacies, very suitable
It is suitable for daily privates nursing and health care.In addition, product temperature of the invention is pure and fresh, fragrance is simple and elegant, has and relieves stress, loosens the heart
Mind calms down the effect of mood, can console from psychological levels user.
It is disclosed by the invention improve female reproductive health compound rhodamine oil, by parts by volume include: 60 parts of Rosa Damascana,
25 parts of cinnamon essential oil, 15 parts of onion essential oil.
Rosa Damascana is known as essential oil queen, and molecular weight is small, can penetrate into cortex and blood vessel rapidly, makes intracorporal deposit
It releases, in addition exclusive powerful antibiotic property and the effect of promoting the sexual maturity, can promote hormone secretion effect, effectively promoting property swashs
Element secretion, improves frigidity and impotence, is fabulous estrualization agent；Onion essential oil is because being rich in volatile sulfide and paddy Guang glycosides
Peptides, therefore there are different physiological roles, it such as prevents and treats artery sclerosis and thrombus, blood pressure lowering, anti-diabetic, improve liver
Dysfunction, resistant to infection disease etc.；Cinnamon essential oil energy eliminating cold to stop pain, is good for fortune spleen taste, has certain therapeutic effect to sombre impotence.
Wherein, the nursing product is prepared by the following method: in proportion measure 60 parts of Rosa Damascana, 25 parts of cinnamon essential oil,
15 parts of onion essential oil, after stirring 1-2h under conditions of 200-300rpm, it is ultrasonically treated 10-15min, ultraviolet sterilization 30-
60min is to get compound rhodamine oil nursing product.
Preferably, the nursing product is prepared by the following method: measuring Rosa Damascana 60ml, cinnamon essential oil 25ml, onion
Essential oil 15ml after stirring 1-2h under conditions of 200-300rpm, is ultrasonically treated 10-15min, ultraviolet sterilization 30-60min, i.e.,
Obtain compound rhodamine oil nursing product.
In addition, the present invention also provides a kind of preparation methods of compound rhodamine oil for improving female reproductive health, by body
Product part weighs 60 parts of Rosa Damascana, 25 parts of cinnamon essential oil, 15 parts of onion essential oil, stirs 1-2h under conditions of 200-300rpm
Afterwards, it is ultrasonically treated 10-15min, ultraviolet sterilization 30-60min is to get compound rhodamine oil nursing product.
In addition, product temperature of the invention is pure and fresh, fragrance is simple and elegant, has and relieves stress, loosens the mind.Compared to single
Essential oil (Rosa Damascana, cinnamon essential oil, onion essential oil), compound rhodamine oil of the invention can effectively promote sex hormone secretion,
With synergistic function, it is very suitable for the nursing of women day privates.
Detailed description of the invention
Fig. 1 is blank group, i.e. the young female sd inbred rats ovary tissue slice of non-administration.
Fig. 2 is menopausal syndrome rat model group, i.e. the climacteric female sd inbred rats ovary tissue slice of non-administration.
The climacteric female sd inbred rats ovary tissue slice of 1 Rosa Damascana is given once daily in Fig. 3 Rosa Damascana group.
The climacteric female sd inbred rats ovary tissue slice of 1 cinnamon essential oil is given once daily in Fig. 4 cinnamon essential oil group.
The climacteric female sd inbred rats ovary tissue slice of 1 onion essential oil is given once daily in Fig. 5 onion essential oil group.
The climacteric female sd inbred rats ovary tissue of 1 compound rhodamine oil is given once daily in Fig. 6 compound rhodamine oil group
Slice.
Specific embodiment
Technical solution of the present invention is described in further detail combined with specific embodiments below, but protection scope of the present invention is not
It is confined to the embodiment.
A kind of compound rhodamine oil and its application method for improving female reproductive health of embodiment 1
Formula:
Rosa Damascana 60ml, cinnamon essential oil 25ml, onion essential oil 15ml.
Preparation: measuring mixing according to the above ratio, after stirring 1-2h under conditions of 200-300rpm, is ultrasonically treated 10-
15min, ultraviolet sterilization 30-60min is to get compound rhodamine oil.
Usage: local use before sexual life is especially used in sensitive region, as after ear, in neck, breast and thigh
Side.The principle of the invention lies in the synergistic effect that different essential oils are utilized, its respectively effect is promoted.
A kind of effect assessment for the essential oil for improving female reproductive health of embodiment 2
1. preparing sample
(1) compound rhodamine oil group sample is compound rhodamine oil made from embodiment 1.
(2) Rosa Damascana group sample is Rosa Damascana used in embodiment 1.
(3) cinnamon essential oil group sample is cinnamon essential oil used in embodiment 1.
(4) onion essential oil group sample is onion essential oil used in embodiment 1.
2. the effect assessment of compound rhodamine oil --- the om observation experiment of hot flushes in rats ovary tissue slice
The rat model of menopausal syndrome research selects 48 the monthly age 11~15 months, and the SD female of weight 280-350g is big
Mouse, Via vagina cast-off cells plate coating checking, selection presentation irregular oestrous cycle are determined as climacteric mouse.It is assigned randomly to mould
Type group, Rosa Damascana group, cinnamon essential oil group, onion essential oil group, compound rhodamine oil group, dip each group using cotton swab by every group 8
Rat private parts is smeared after corresponding essential oil, is administered once daily, successive administration 30 days, 8 hot flushes in rats of model group, with life
Salt water is managed to replace；Optionally the monthly age 3-5 month, weight 150-210g female sd inbred rats 8 are only used as blank control, and 6 groups of animals are broken simultaneously
Head is put to death, and ovary is won, and is set fixed in 10% formalin solution.It is dyed again through dehydration, embedding, slice, HE.
The ovary of blank group, under low power lens, it is seen that a large amount of primordial follicles and size, primary follicle in varying numbers,
Antral follicle count, interstitial gland enrich (Fig. 1))；The ovary of menopausal syndrome rat model, under low power lens, it is seen that primordial follicle,
Primary follicle and antral follicle count are less, and interstitial gland is sparse (Fig. 2), show without enough sex hormone and progesterone secretion；Rhodamine toner
Oily group, cinnamon essential oil group, onion essential oil group (Fig. 3,4,5), under low power lens, primordial follicle, primary follicle and antral follicle count,
Matter gland relative model group is more than blank group, shows that sex hormone and progesterone secretion increase；Compound rhodamine oil group, can under low power lens
Seeing has a fairly large number of primordial follicle, primary follicle and antral follicle count, relative to model group and Rosa Damascana group, cinnamon essential oil
Group, onion essential oil group are all more, show sex hormone and progesterone secretion at most (Fig. 6).
To sum up illustrate, compared to single essential oil (Rosa Damascana, cinnamon essential oil, onion essential oil), compound rose of the invention
Rare essential oil can effectively promote sex hormone secretion, have synergistic function, be very suitable for the nursing of women day privates.
Claims (4)
1. it is a kind of improve female reproductive health compound rhodamine oil, by parts by volume by 60 parts of Rosa Damascana, 25 parts of cinnamon essential oil,
15 parts of onion essential oil compositions.
2. improving the compound rhodamine oil of female reproductive health as described in claim 1, it is characterised in that the compound rose
Rare essential oil is prepared by the following method: 60 parts of Rosa Damascana of measurement, 25 parts of cinnamon essential oil and 15 parts of onion essential oil in proportion,
After stirring 1-2h under conditions of 200-300rpm, it is ultrasonically treated 10-15min, ultraviolet sterilization 30-60min is to get compound rhodamine toner
Oil.
3. improving the compound rhodamine oil of female reproductive health as claimed in claim 2, it is characterised in that the compound rose
Rare essential oil is prepared by the following method: Rosa Damascana 60ml, cinnamon essential oil 25ml, onion essential oil 15ml is measured, in 200-300rpm
Under conditions of stir 1-2h after, be ultrasonically treated 10-15min, ultraviolet sterilization 30-60min is to get compound rhodamine oil.
4. improving the preparation method of the compound rhodamine oil of female reproductive health as described in claim 1, preparation method is such as
Under: 60 parts of Rosa Damascana, 25 parts of cinnamon essential oil are weighed by parts by volume, 15 parts of onion essential oil, is stirred under conditions of 200-300rpm
After mixing 1-2h, it is ultrasonically treated 10-15min, ultraviolet sterilization 30-60min is to get compound rhodamine oil.
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| CN201610939044.XA CN106563174B (en) | 2016-10-25 | 2016-10-25 | A kind of compound rhodamine oil and preparation method thereof improving female reproductive health |
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| KR100434729B1 (en) * | 1998-03-18 | 2004-11-03 | 주식회사 엘지생명과학 | Method for improving production yield of erythropoietin from chinese hamster ovary(cho) by adding natural extracts in serum free medium, while reducing production cost |
| CN104224923A (en) * | 2014-07-07 | 2014-12-24 | 海南华拓天涯制药有限公司 | Tea tree essential oil antimicrobial gel for treating vaginal disease in gynecology |
| AU2015326419A1 (en) * | 2014-09-29 | 2017-04-06 | Botanocap Ltd. | Non-woven fabric containing microencapsulated essential oils for preservation of crops |
| CN105581926B (en) * | 2016-02-25 | 2018-10-30 | 刘忠波 | Women privates conditioning liquid and preparation method thereof |
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