CN106560579B - Control system for temperature field subarea of deep low-temperature environment - Google Patents
Control system for temperature field subarea of deep low-temperature environment Download PDFInfo
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- CN106560579B CN106560579B CN201610840577.2A CN201610840577A CN106560579B CN 106560579 B CN106560579 B CN 106560579B CN 201610840577 A CN201610840577 A CN 201610840577A CN 106560579 B CN106560579 B CN 106560579B
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- E—FIXED CONSTRUCTIONS
- E04—BUILDING
- E04H—BUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
- E04H5/00—Buildings or groups of buildings for industrial or agricultural purposes
- E04H5/02—Buildings or groups of buildings for industrial purposes, e.g. for power-plants or factories
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D3/00—Devices using other cold materials; Devices using cold-storage bodies
- F25D3/10—Devices using other cold materials; Devices using cold-storage bodies using liquefied gases, e.g. liquid air
- F25D3/102—Stationary cabinets
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Abstract
The invention discloses a control system for temperature field subareas in a deep low-temperature environment, which comprises an operation area and an area to be operated, wherein heat-insulating layers are arranged on the outer sides of the operation area and the area to be operated, and the operation area and the area to be operated are separated by a heat-insulating wall and are connected by a communication port; the operation area is a cavity with an opening at the top, the upper part of the operation area is provided with a heating area, two side surfaces of the operation area are provided with a plurality of through holes, a bottom liquid nitrogen tank and a side surrounding liquid nitrogen tank are arranged in the operation area, the tops of the bottom liquid nitrogen tank and the side surrounding liquid nitrogen tank are respectively provided with an operation area liquid nitrogen spray pipe in a penetrating way, and the bottoms of the bottom liquid nitrogen tank and the side surrounding liquid nitrogen tank are respectively connected with a liquid nitrogen collecting return pipe; the operation area is a closed cavity, and a liquid nitrogen spray pipe of the operation area is arranged at the top of the operation area in a penetrating way. The invention applies a specially designed three-dimensional liquid nitrogen cooling system and is matched with a partition heat-insulating layer to realize partition and layering of a temperature field according to an ideal state, thereby not only ensuring the activity of a biological sample, but also enabling an automatic device to normally work and avoiding the high cost of special equipment.
Description
Technical Field
The invention relates to a control system for temperature field subareas in a deep low-temperature environment.
Background
At present, automation equipment is widely applied to the fields of industry, medical treatment, office, household and the like, automatic operation of biological sample access is also realized, but in the whole operation process, the biological sample is in a deep low-temperature environment, and a common automation device cannot be used.
The common automatic device for accessing biological samples comprises the following main components: the machine comprises a machine body, a power part, a detection part, an actuating mechanism and a controller, wherein the working temperature of the general power part, the detection part, the actuating mechanism and the controller is basically-40-60 ℃, and the general power part, the detection part, the actuating mechanism and the controller cannot work in a deep low temperature environment (below-130 ℃); if the device is in a deep low temperature environment, the problems of reduced precision, solidified lubricating grease, shrinkage and blocking of mechanism materials, embrittlement of plastic parts, damage of electronic elements and the like can occur. For the automatic device working environment zone control system for biological sample access, the temperature of the bottom sample storage zone needs to be controlled at a deep low temperature; the working environments of the power part, the detection part, the actuating mechanism and the controller are required to be controlled at conventional temperatures all the time; and the freezing tube clamping jaw or the suction tube as the mechanical body can extend into a deep low-temperature area to pick the tube. If the whole system is to work in a cryogenic environment, special materials and a special lubricating mode or special heating and heat preservation measures are needed, so the manufacturing cost is high.
Disclosure of Invention
The invention provides a deep low temperature environment temperature field zoning control system capable of helping an automation device to normally work, aiming at solving the problem that the automation device is difficult to normally work in the deep low temperature environment in the prior art.
The invention solves the technical problems through the following technical scheme:
the invention provides a control system for temperature field subareas in a deep low-temperature environment, which comprises an operation area and an area to be operated, wherein heat-insulating layers are arranged on the outer sides of the operation area and the area to be operated, and the operation area and the area to be operated are separated by a heat-insulating wall and are connected by a communication port; the operation area is a cavity with an opening at the top, a heating area is arranged at the top of the operation area, a plurality of through holes are arranged on two side surfaces of the operation area, a bottom liquid nitrogen tank is arranged in the center of the bottom surface of the operation area, side surrounding liquid nitrogen tanks are arranged on the periphery of the bottom surface of the operation area, operation area liquid nitrogen spray pipes are arranged at the tops of the bottom liquid nitrogen tank and the side surrounding liquid nitrogen tanks in a penetrating manner, and the bottoms of the bottom liquid nitrogen tank and the side surrounding liquid nitrogen tanks are connected with a liquid nitrogen collecting return pipe; treat that the operation district is a closed cavity, treat that the top in operation district wears to be equipped with and waits to operate the district liquid nitrogen spray tube, treat that the bottom in operation district is equipped with the sample entry of a switch formula.
In the invention, the heat-insulating layer and the heat-insulating wall body are preferably made of heat-insulating materials, and the heat-insulating materials are one of polyurethane foaming materials, vacuum heat-insulating board materials, XPS extruded sheet materials or polypropylene foam plastics.
In the present invention, the communication port is preferably provided below the thermal insulation wall, and serves as a passage for sample transfer and cold air circulation.
In the present invention, the height of the communication port is preferably 1/4, which is the height of the working space.
In the present invention, the area of the communication port is preferably 1/5 of the area of the bottom of the working space.
In the present invention, the distance between the position of the through hole and the bottom of the working area is preferably 0.3 times the height of the working area.
In the present invention, the top of the heating zone is flush with the top of the working zone, and the thickness of the heating zone is preferably 1/4 the height of the working zone.
In the present invention, a heating element is preferably disposed in the working area, and the heating element is one of a heating wire, a heating ring or a heating sheet.
In the present invention, a cover plate is preferably disposed on the top of the operation area, and the cover plate is located above the heating area; the cover plate is preferably of a sliding or single-axis outward opening type, preferably made of a non-insulating material, which is one of steel, aluminum or copper.
In the present invention, the bottom liquid nitrogen tank is preferably of a top opening structure.
In the invention, the side-surrounding liquid nitrogen tanks are preferably of split structures at corners, and the split side-surrounding liquid nitrogen tanks are connected through liquid nitrogen pipes.
In the present invention, the side is preferably provided with a cover plate around the top of the liquid nitrogen tank.
In the invention, a plurality of waist-shaped holes are preferably arranged on the side surface of the side surrounding liquid nitrogen tank in the central direction facing the operation area; more preferably, the height of the waist-shaped hole is 1/2-3/4 of the height of the side surrounding the liquid nitrogen tank.
In the invention, the part of the operation area liquid nitrogen spray pipe penetrating through the bottom liquid nitrogen tank and the side surrounding the liquid nitrogen tank is preferably provided with downward liquid nitrogen spray holes.
In the invention, the part of the liquid nitrogen spray pipe of the area to be operated, which penetrates through the inside of the area to be operated, is preferably provided with downward liquid nitrogen spray holes.
In the invention, the height of the liquid nitrogen spray pipe of the area to be operated is preferably 0.95 times of the height of the area to be operated.
In the present invention, the sample inlet is preferably provided with a cover plate, which is preferably of a sliding or uniaxial outward opening type, preferably made of the heat insulating material.
On the basis of the common knowledge in the field, the above preferred conditions can be combined randomly to obtain the preferred embodiments of the invention.
The positive progress effects of the invention are as follows: the invention applies a specially designed three-dimensional liquid nitrogen cooling system and is matched with a partition heat-insulating layer to realize partition and layering of a temperature field according to an ideal state, thereby not only preventing a biological sample from being exposed to a normal temperature environment and ensuring the activity of the sample, but also preventing an automatic mechanism at the upper part of an operation area from being damaged in a deep low temperature environment, ensuring the normal work of the automatic device and avoiding the high cost of applying special equipment.
Drawings
FIG. 1 is a system diagram of the preferred embodiment of the present invention.
FIG. 2 is a schematic structural diagram of an operation area and an area to be operated according to a preferred embodiment of the present invention.
FIG. 3 is a schematic diagram of the temperature distribution in the operation area according to the preferred embodiment of the present invention.
Detailed Description
The invention is further illustrated by the following examples, which are not intended to limit the scope of the invention.
As shown in fig. 1-2, a temperature field zoning control system for a deep low temperature environment comprises an operation zone and a zone to be operated, wherein heat insulation layers 2 are respectively arranged at the outer sides of the operation zone and the zone to be operated; the operation area is a cavity with an opening at the top, the top of the operation area is provided with a heating area 9, the thickness of the heating area 9 is 1/4 of the height of the operation area, two side surfaces of the operation area are provided with a plurality of through holes 10, the center of the bottom surface of the operation area is provided with a bottom liquid nitrogen tank 5, the periphery of the bottom surface of the operation area is provided with side surrounding liquid nitrogen tanks 6, the tops of the bottom liquid nitrogen tank 5 and the side surrounding liquid nitrogen tanks 6 are both provided with operation area liquid nitrogen spray pipes 4 in a penetrating manner, and the bottoms of the bottom liquid nitrogen tanks 5 and the side surrounding liquid nitrogen tanks 6 are both connected with a liquid nitrogen collecting return pipe 3; the to-be-operated area is a closed cavity, the top of the to-be-operated area is penetrated by a liquid nitrogen spray pipe 1 of the to-be-operated area, and the bottom of the to-be-operated area is provided with a switchable sample inlet 8; bottom liquid nitrogen tank 5 is open-top structure, the side encircles liquid nitrogen tank 6 and adopts split type structure in the corner, and is split type the side encircles through the liquid nitrogen union coupling between the liquid nitrogen tank, the side encircles the top of liquid nitrogen tank 6 and is equipped with the apron, the side that the side encircles liquid nitrogen tank 6 is in towards be equipped with a plurality of waist shape holes on the central direction in operation district, the height in waist shape hole does the side encircles 1/2-3/4 around the height of liquid nitrogen tank 6, operation district liquid nitrogen spray tube 4 wears to locate bottom liquid nitrogen tank 5 reaches the part that the liquid nitrogen tank 6 was surrounded to the side is equipped with decurrent liquid nitrogen orifice, treat that operation district liquid nitrogen spray tube 1 wears to locate treat that the inside part in operation district is equipped with decurrent liquid nitrogen orifice, treat that the height of operation district spray tube 1 is for treat that the height in operation district is 0.95 times the height in operation district.
The operation area and the area to be operated are separated by a heat insulation wall and are connected through a communication port 7, the height of the communication port 7 is 1/4 of the height of the operation area, the area of the communication port 7 is 1/5 of the bottom area of the operation area, the height of the through hole 10 is 0.3 times of the height of the operation area, and the sample inlet 8 is provided with a sliding type cover plate which is preferably made of a heat insulation material.
When the device is used, firstly, liquid nitrogen is sprayed to the area to be operated in the heat-insulating layer 2 through the liquid nitrogen spray pipe 1 of the area to be operated, the space of the area to be operated can be integrally cooled in the process that cold air sinks from the top, and the uniform distribution of temperature can be realized after a period of time; meanwhile, the liquid nitrogen spray pipe 4 of the operation area sprays liquid nitrogen into the liquid nitrogen tank 5 at the bottom and the side surrounding liquid nitrogen tank 6, cold air overflows outwards through the top of the liquid nitrogen tank 5 at the bottom and the waist-shaped hole of the side surrounding liquid nitrogen tank 6, the cold air of the operation area flows to the operation area through the communication port 7, and the cold air naturally sinks and is intensively distributed at the bottom of the operation area due to small air convection of the operation area, so that the temperature of the space below the waist-shaped hole of the side surrounding liquid nitrogen tank 6 is extremely low; the space above the waist-shaped hole is only subjected to the action of heat radiation and heat conduction, so that the heat transfer efficiency is low, the cooling effect is weakened, the micro-positive pressure environment is kept in the cavity due to the vaporization of the liquid nitrogen, and partial cold air overflows from the through holes 10 on the left side and the right side of the cavity outwards, so that the heat transfer to the upper space is further reduced; the top of the working area is a heating area 9 and is provided with heating elements, which are at a higher temperature and transfer heat to the lower space. The surplus liquid nitrogen flows back to the liquid nitrogen container through the liquid nitrogen collecting return pipe 3. And redundant liquid nitrogen sprayed out by the liquid nitrogen spray pipe 1 in the area to be operated flows back to the liquid nitrogen container through a sample inlet in the heat-insulating layer 2.
As shown in fig. 3, under the combined action of the above structures, the temperature of the whole working area is obviously layered from bottom to top, wherein the horizontal axis represents the height of the working area: the 0-A area is a freezing tube placing area, the temperature of the freezing tube placing area is lower than-130 ℃, and the biological sample is ensured to be in a deep low-temperature storage environment; the B-C area is an area where the clamping motor is located, the temperature of the B-C area is-40 to-30 ℃, and the mechanical part of the automation device, namely the clamping motor and the like, can be ensured to normally work at the temperature; the D-E area is the area where the electric cylinder is located, and the temperature of the D-E area is 0-room temperature, so that the normal work of a power part of the automation device, even a detection part, an execution mechanism, a controller and other equipment at the same height can be guaranteed. In general, the invention can ensure that the biological sample is well preserved in a deep low temperature environment, and simultaneously, the respective motorized devices can normally work at an ideal temperature.
While specific embodiments of the invention have been described above, it will be appreciated by those skilled in the art that these are by way of example only, and that the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the spirit and scope of the invention, and these changes and modifications are within the scope of the invention.
Claims (9)
1. A temperature field zoning control system in a deep low temperature environment is characterized by comprising an operation zone and a zone to be operated, wherein heat insulation layers are arranged on the outer sides of the operation zone and the zone to be operated, and the operation zone and the zone to be operated are separated by a heat insulation wall and are connected through a communication port; the operation area is a cavity with an opening at the top, a heating area is arranged at the top of the operation area, a plurality of through holes are arranged on two side surfaces of the operation area, a bottom liquid nitrogen tank is arranged in the center of the bottom surface of the operation area, side surrounding liquid nitrogen tanks are arranged on the periphery of the bottom surface of the operation area, operation area liquid nitrogen spray pipes are arranged at the tops of the bottom liquid nitrogen tank and the side surrounding liquid nitrogen tanks in a penetrating manner, and the bottoms of the bottom liquid nitrogen tank and the side surrounding liquid nitrogen tanks are connected with a liquid nitrogen collecting return pipe; the device comprises a to-be-operated area, a liquid nitrogen spray pipe, a sample inlet, a sample outlet, a sample collecting pipe and a sample collecting pipe, wherein the to-be-operated area is a closed cavity, the top of the to-be-operated area is penetrated with the liquid nitrogen spray pipe, and the bottom of the to-be-operated area is provided with the sample inlet which can be opened and closed;
the side surface of the side surrounding liquid nitrogen tank is provided with a plurality of waist-shaped holes in the central direction facing the operation area, and the height of each waist-shaped hole is 1/2-3/4 of the height of the side surrounding liquid nitrogen tank.
2. The profound hypothermia environment temperature field zoning control system of claim 1, wherein the insulation layer and the insulation wall are made of insulation material, and the insulation material is one of polyurethane foam material, vacuum insulation board material, XPS extruded board material or polypropylene foam plastic.
3. The profound hypothermia ambient temperature field zoning control system of claim 1, wherein the communication port is provided below the thermal insulation wall, the height of the communication port is 1/4 of the height of the working zone, and the area of the communication port is 1/5 of the bottom area of the working zone;
the distance between the position of the through hole and the bottom of the operation area is 0.3 times of the height of the operation area.
4. The profound hypothermia ambient temperature field zoning control system of claim 1, wherein a top of the heating zone is flush with a top of the work zone, a thickness of the heating zone being 1/4 of a height of the work zone;
a heating element is arranged in the operation area, and the heating element is one of a heating wire, a heating ring or a heating sheet;
the top in operation district is equipped with a apron, the apron is located on the district of heating, the apron is slidingtype or unipolar outward opening, the apron is made by non-insulation material, non-insulation material is one of steel, aluminium or copper.
5. The profound hypothermia ambient temperature field zoning control system of claim 1 wherein the bottom liquid nitrogen bath is of an open-topped configuration.
6. The profound hypothermia environment temperature field zoning control system of claim 1, wherein the side surrounding liquid nitrogen tank adopts a split type structure at a corner, the split type side surrounding liquid nitrogen tank is connected with each other through a liquid nitrogen pipe, and a cover plate is arranged at the top of the side surrounding liquid nitrogen tank.
7. The cryogenic environment temperature field zoning control system according to claim 1, wherein the operating zone liquid nitrogen spray pipe is provided with downward liquid nitrogen spray holes at the part where the operating zone liquid nitrogen spray pipe penetrates through the bottom liquid nitrogen tank and the side surrounding the liquid nitrogen tank, and the part where the operating zone liquid nitrogen spray pipe penetrates through the inside of the operating zone is provided with downward liquid nitrogen spray holes.
8. The profound hypothermia environment temperature field zoning control system according to claim 1, wherein the height of the liquid nitrogen spraying pipe of the area to be operated is 0.95 times the height of the area to be operated.
9. The cryogenic environment temperature field zoning control system of claim 1, wherein the sample inlet is provided with a cover plate, the cover plate is a sliding type or a single shaft outward opening type, the cover plate is made of an insulation material, and the insulation material is one of a polyurethane foam material, a vacuum insulation plate material, an XPS extruded plate material or a polypropylene foam plastic.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610840577.2A CN106560579B (en) | 2016-09-21 | 2016-09-21 | Control system for temperature field subarea of deep low-temperature environment |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610840577.2A CN106560579B (en) | 2016-09-21 | 2016-09-21 | Control system for temperature field subarea of deep low-temperature environment |
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| CN106560579A CN106560579A (en) | 2017-04-12 |
| CN106560579B true CN106560579B (en) | 2022-03-01 |
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| CN109335325B (en) * | 2018-10-09 | 2023-06-27 | 上海原能细胞生物低温设备有限公司 | Biological sample partition cooling storage device and operation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ATE166221T1 (en) * | 1993-07-06 | 1998-06-15 | Cryonic Medical | CRYOTHERAPY FACILITY |
| US6332325B1 (en) * | 2000-08-17 | 2001-12-25 | Coldfire Technolgy, Inc. | Apparatus and method for strengthening articles of manufacture through cryogenic thermal cycling |
| CN201184718Y (en) * | 2008-02-19 | 2009-01-21 | 王绍钢 | Ultra-low-temperature recycle equipment |
| CN101628245A (en) * | 2009-07-31 | 2010-01-20 | 杭州凯德空分设备有限公司 | Test performing device for deep low-temperature substance |
| CN203163381U (en) * | 2013-02-21 | 2013-08-28 | 中国科学院理化技术研究所 | Cryogenic treatment equipment with cold energy recovery device |
| CN103983065A (en) * | 2014-05-04 | 2014-08-13 | 南通天工深冷新材料强化有限公司 | Cryogenic treatment tank with uniformly-distributed cold medium |
| CN105211050B (en) * | 2015-10-22 | 2017-12-12 | 上海原能细胞医学技术有限公司 | Operating desk for freeze-stored cell |
| CN105650959B (en) * | 2015-12-31 | 2017-12-05 | 上海振华重工集团(南通)传动机械有限公司 | A kind of liquid nitrogen cooling device and its assembly method |
| CN105737471B (en) * | 2016-02-04 | 2018-08-31 | 上海理工大学 | Quickly cooling portable biometric sample Cord blood case |
| CN105857941B (en) * | 2016-04-28 | 2018-06-29 | 上海原能健康管理有限公司 | Cryopreservation tube access device |
| CN206091410U (en) * | 2016-09-21 | 2017-04-12 | 原能细胞科技集团有限公司 | Dark low temperature environment temperature field zone control system |
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Effective date of registration: 20200123 Address after: 200120 Room 102, floor 1, building 4, no.1227, zhangheng road and no.1118, Halley Road, China (Shanghai) pilot Free Trade Zone, Pudong New Area, Shanghai Applicant after: Shanghai primary cell biological low temperature Equipment Co Ltd Address before: 201299, Shanghai, Pudong New Area Zhou Zhu Road No. 9, building 313, room 337 Applicant before: ORIGINCELL TECHNOLOGY GROUP CO., LTD. Applicant before: SHANGHAI ORIGINCELL MEDICAL TECHNOLOGY Co.,Ltd. Applicant before: Shanghai Original Health Management Co., Ltd. |
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