CN106543372A - Ophthalmic lens materials, eye lens and intraocular lens - Google Patents
Ophthalmic lens materials, eye lens and intraocular lens Download PDFInfo
- Publication number
- CN106543372A CN106543372A CN201510601068.XA CN201510601068A CN106543372A CN 106543372 A CN106543372 A CN 106543372A CN 201510601068 A CN201510601068 A CN 201510601068A CN 106543372 A CN106543372 A CN 106543372A
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- China
- Prior art keywords
- matrix
- lens
- natural yellow
- eye lens
- lutein
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Abstract
A kind of eye lens, including matrix and the natural yellow dyestuff being mixed in the matrix, the natural yellow dyestuff include lutein and at least one in maize quality.The present invention also provides a kind of intraocular lens, and for preparing the ophthalmic lens materials of above-mentioned eye lens and intraocular lens.
Description
Technical field
The present invention relates to a kind of ophthalmic lens materials, and prepared by the ophthalmic lens materials
Eye lens and intraocular lens.
Background technology
It is well known that the sun can send ultraviolet (UV), visible ray (visible) and infrared
Line (IR).Most of infrared rays can be absorbed by atmosphere, and visible ray (wavelength about between
400-700nm) and near infrared ray (wavelength is about between 700-1400nm) can penetrate atmosphere and arrive
Up to earth surface.Blue light (wavelength is about between 450-500nm) in visible ray may be to regarding
Nethike embrane is damaged.Furthermore, most electronic products are (such as liquid crystal display, light-emitting diodes
Pipe, mobile phone screen or computer screen) etc. also with the backlight module that can send blue light.
These blue lights may injure retina and increased the possibility of macular diseases, or even make
Into the damage that cannot be restored.
The content of the invention
In view of this, it is necessary to which a kind of eye lens for being capable of block blue light and artificial crystalline substance are provided
Shape body, can solve the problem that problem above.
Separately, there is a need to and provide a kind of for preparing above-mentioned eye lens and intraocular lens
Ophthalmic lens materials.
The present invention provides a kind of eye lens, including matrix and the day being mixed in the matrix
Right weld, the natural yellow dyestuff are included in lutein and maize quality at least
It is a kind of.
The present invention also provides a kind of intraocular lens, including matrix and is mixed in the matrix
Natural yellow dyestuff, during the natural yellow dyestuff includes lutein and maize quality
It is at least one.
The present invention also provides a kind of ophthalmic lens materials, for preparing eye lens or artificial water
Crystal, the ophthalmic lens materials include natural yellow dyestuff, hydrophilic monomer, hydrated polymer
Thing, light trigger and crosslinking agent, wherein, under ultraviolet light, the hydrophily list
After body and hydrated polymer can be copolymerized in the presence of light trigger and crosslinking agent
Matrix is formed, the natural yellow dyestuff is mixed in the matrix, the natural yellow dyestuff bag
Include lutein and at least one in maize quality.
Natural yellow dyestuff in the eye lens of the present invention can Jing veterinary antibiotics, fish etc.
Extracted in food easily, additionally, the natural yellow dyestuff can filter the blue light of surrounding environment with
The damage for effectively reducing or avoiding blue light to cause to retina, can also provide necessary for eyes
Nutrient and then protect eyes.
Specific embodiment
Better embodiment of the present invention provides a kind of eye lens or intraocular lens (IOLs),
Its natural yellow dyestuff for including matrix and being mixed in the matrix.The natural yellow dyestuff
For filtering the blue light of surrounding environment effectively to reduce or avoid the damage that blue light causes retina
Wound, can also provide necessary nutrient and then protect eyes for eyes.Wherein, the natural yellow
Dyestuff is included in lutein (lutein) and maize quality (zeaxanthin) at least
It is a kind of.Lutein and maize quality are two Carotenoids being widely present in the Nature,
Which can be extracted in food such as Jing veterinary antibiotics, fish easily.Wherein, the eye lens can
To be contact lenses, more specifically, the eye lens are hydrogel lenses or silicone-hydrogel mirror
Piece.
In the present embodiment, the shared quality in the eye lens of the natural yellow dyestuff
Percentage is 0.0001%-0.5%.
In the present embodiment, the natural yellow dyestuff includes lutein and maize quality,
The shared mass percent in the eye lens of lutein and maize quality is
0.00005%-0.25%.
In the present embodiment, when the eye lens are hydrogel lenses, the matrix is water
Gel；When the eye lens are silicone hydrogel lenses, the matrix is silicone-hydrogel.Wherein,
The hydrogel and silicone-hydrogel by hydrophilic monomer and hydrated polymer light trigger with
And formed after being copolymerized in the presence of crosslinking agent.Wherein, the hydrated polymer does
For hydrogel and the main chain of silicone-hydrogel, the hydrophilic monomer is used as hydrogel and silicon water-setting
In glue, functional monomer is increasing the performances such as its hydrophily and oxygen permeability.
More specifically, when the matrix is hydrogel, the hydrophilic monomer may be selected from N-
Vinyl pyrrolidone (NVP), GMA (GMA) and N, N-
One of which in DMAA (DMAA), the hydrated polymer may include first
Base methyl acrylate (MMA) and hydroxyethyl methacrylate (HEMA).When the base
When body is silicone-hydrogel, the hydrophilic monomer can be NVP (NVP),
The hydrated polymer may include methyl methacrylate (MMA), hydroxyethyl methacrylate second
Ester (HEMA), dimethyl silicone polymer (PDMS) and trishydroxymethylaminomethane
(TRIS).Wherein, the light trigger can adopt Irgacure-1173 (chemical industry marks
Pseudotype number), the crosslinking agent can adopt GDMA (EGDMA).
The present invention is specifically described below by embodiment.
Embodiment 1
The lutein that eye lens include hydrogel and are mixed in the hydrogel, lutein
In the eye lens, shared mass percent is 0.4%.
Embodiment 2
Eye lens include hydrogel and the lutein that is mixed in the hydrogel and maize
The shared mass percent in the eye lens of quality, lutein and maize quality is
0.2%.
Embodiment 3
Eye lens include silicone-hydrogel and the lutein that is mixed in the silicone-hydrogel and jade
The shared mass percent in the eye lens of cream-coloured quality, lutein and maize quality
It is 0.15%.
The present invention also provides a kind of for preparing the ophthalmically acceptable of above-mentioned eye lens or intraocular lens
Lens materials, which includes that natural yellow dyestuff, hydrophilic monomer, hydrated polymer, light draw
Agent and crosslinking agent are sent out, wherein, under ultraviolet light, the hydrophilic monomer and hydration
Polymer can form base after being copolymerized in the presence of light trigger and crosslinking agent
Body, makes the natural yellow dyestuff be mixed in the matrix.The natural yellow dyestuff includes that leaf is yellow
At least one in element and maize quality.
In addition, for the person of ordinary skill of the art, can be with skill of the invention
Art design make other it is various it is corresponding change with deformation, and it is all these change and deform all
The protection domain of the claims in the present invention should be belonged to.
Claims (8)
1. a kind of eye lens, including matrix and the natural yellow dye being mixed in the matrix
Material, the natural yellow dyestuff include lutein and at least one in maize quality.
2. eye lens as claimed in claim 1, it is characterised in that the natural yellow contaminates
The shared mass percent in the eye lens of material is 0.0001%-0.5%.
3. eye lens as claimed in claim 1, it is characterised in that the natural yellow contaminates
Material include lutein and maize quality, lutein and maize quality in the ophthalmically acceptable mirror
In piece, shared mass percent is 0.00005%-0.25%.
4. eye lens as claimed in claim 1, it is characterised in that the matrix is water-setting
Glue or silicone-hydrogel.
5. a kind of intraocular lens, including matrix and the natural yellow being mixed in the matrix
Dyestuff, the natural yellow dyestuff include lutein and at least one in maize quality.
6. a kind of ophthalmic lens materials, for preparing eye lens or intraocular lens, which is special
Levy and be, the ophthalmic lens materials include that natural yellow dyestuff, hydrophilic monomer, hydration are poly-
Compound, light trigger and crosslinking agent, wherein, under ultraviolet light, the hydrophily
Monomer and hydrated polymer can be copolymerized in the presence of light trigger and crosslinking agent
After form matrix, the natural yellow dyestuff is mixed in the matrix, the natural yellow dyestuff
Including at least one in lutein and maize quality.
7. ophthalmic lens materials as described in claim 6, it is characterised in that the matrix
For hydrogel, the hydrophilic monomer is selected from NVP, methacrylic acid contracting
The one of which of water glyceride and N,N-DMAA, the hydrated polymer bag
Include methyl methacrylate and hydroxyethyl methacrylate.
8. ophthalmic lens materials as described in claim 6, it is characterised in that the matrix
For silicone-hydrogel, the hydrophilic monomer is NVP, the hydrated polymer
Thing include methyl methacrylate, hydroxyethyl methacrylate, dimethyl silicone polymer and
Trishydroxymethylaminomethane.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510601068.XA CN106543372A (en) | 2015-09-18 | 2015-09-18 | Ophthalmic lens materials, eye lens and intraocular lens |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510601068.XA CN106543372A (en) | 2015-09-18 | 2015-09-18 | Ophthalmic lens materials, eye lens and intraocular lens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106543372A true CN106543372A (en) | 2017-03-29 |
Family
ID=58363045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510601068.XA Pending CN106543372A (en) | 2015-09-18 | 2015-09-18 | Ophthalmic lens materials, eye lens and intraocular lens |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106543372A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113549233A (en) * | 2021-07-20 | 2021-10-26 | 北京沃视医疗科技有限公司 | Preparation method of lutein injection type eye protection substrate |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101151332A (en) * | 2005-04-08 | 2008-03-26 | 株式会社美你康 | Novel polymerizable dye and ophthalmic lens containing the same |
| CN102439512A (en) * | 2009-03-25 | 2012-05-02 | 高效光学技术有限公司 | Photochromic ophthalmic systems that selectively filter specific blue light wavelengths |
| CN103941320A (en) * | 2014-04-08 | 2014-07-23 | 丁鹏飞 | Device for selectively filtering light rays |
| CN103998974A (en) * | 2011-12-08 | 2014-08-20 | 埃西勒国际通用光学公司 | Ophthalmic filter |
-
2015
- 2015-09-18 CN CN201510601068.XA patent/CN106543372A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101151332A (en) * | 2005-04-08 | 2008-03-26 | 株式会社美你康 | Novel polymerizable dye and ophthalmic lens containing the same |
| CN102439512A (en) * | 2009-03-25 | 2012-05-02 | 高效光学技术有限公司 | Photochromic ophthalmic systems that selectively filter specific blue light wavelengths |
| CN103998974A (en) * | 2011-12-08 | 2014-08-20 | 埃西勒国际通用光学公司 | Ophthalmic filter |
| CN103941320A (en) * | 2014-04-08 | 2014-07-23 | 丁鹏飞 | Device for selectively filtering light rays |
Non-Patent Citations (1)
| Title |
|---|
| 杨国俊等: "眼镜镜片中的化学", 《化学教学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113549233A (en) * | 2021-07-20 | 2021-10-26 | 北京沃视医疗科技有限公司 | Preparation method of lutein injection type eye protection substrate |
| CN113549233B (en) * | 2021-07-20 | 2023-04-28 | 北京沃视医疗科技有限公司 | Preparation method of lutein injection type eye protection substrate |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20170329 |