CN106539819A - A kind of method that hyperoxia Medical liquid treats cerebral infarction - Google Patents
A kind of method that hyperoxia Medical liquid treats cerebral infarction Download PDFInfo
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- CN106539819A CN106539819A CN201510596837.1A CN201510596837A CN106539819A CN 106539819 A CN106539819 A CN 106539819A CN 201510596837 A CN201510596837 A CN 201510596837A CN 106539819 A CN106539819 A CN 106539819A
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Abstract
A kind of method that hyperoxia Medical liquid treats cerebral infarction, base fluid after the process of GY-1 type hyperxia medical fluids therapeutic instrument, with 5%GS liquid 250ml (the high person's normal saline of blood glucose), through hyperoxia instrument flow be 4L/min process after high-concentration oxygen fill it is molten after, add XUESAITONG ZHUSHEYE 400mg, intravenous drip, PaO2 rises to 100 ~ 120kPa by 21kPa, combine the input of corresponding Chinese medicine extract (Shu Xue-tong, XUESAITONG, Herba Erigerontiss etc.) vein again, one time a day, 10 1 courses for the treatment of, general treatment phase are 2 ~ 3 courses for the treatment of.Mitigating cardiovascular and cerebrovascular vessel ischemia symptom, help functional recovery of paralyzed limb and quality etc. of making the life better has obvious effect, there is preferably improvement to the microcirculation disturbance that extremity macroangiopathy and microangiopathies cause, cerebral infarction and diabetic cerebrovascular disease are become curative effect certainly.
Description
Technical field
The present invention relates to a kind of method that hyperoxia Medical liquid treats cerebral infarction, the method that specifically a kind of hyperoxia Medical liquid treats cerebral infarction.
Background technology
Currently known cerebral infarction is one of disease of serious harm human health.Research shows, disability rate and incidence rate is higher again after cerebral infarction, and it is not good that the usual prognosis of patient of cerebral infarction occurs again.After generation acute cerebral infarction, cerebral cell ischemia, anoxia, intracellular energy is lacked, intraor extracellular ion imbalance, ionic pump operating stop, and cause intracellular edema and Interstitial edema, so that calcium channel is opened, cause intracellular overload, cause cerebral tissue secondary lesion, so as to form the vicious cycle of " cerebral anoxia-cerebral edema ".In this vicious cycle, microcirculation disturbance is basis, and anoxia is key link, therefore improves microcirculation disturbance in time, increases brain cell oxygen supply, so that it may block its vicious cycle.
The content of the invention
Diagnostic criteria：
1. object of study：Cerebral infarction case 321, wherein man 172, female 149;It is the oldest 87 years old, minimum 46 years old;Curer 65 in curer 35 in morbidity 1 month, morbidity 3 months, more than 6 months persons of morbidity 221.All cases with 5%GS liquid 250ml (the high person's normal saline of blood glucose), the high-concentration oxygen after hyperoxia instrument flow is 4L/min process fill it is molten after, add XUESAITONG ZHUSHEYE 400mg, intravenous drip, one time a day, and 10 times is 1 course for the treatment of, and the general treatment phase is 2 ~ 3 courses for the treatment of.2. Outcome measure and result；Curative effect judging standard effectively (limbs disturbance, language function obstacle are wholly absent, and recover orthobiosiss);Take a turn for the better (limbs disturbance, language function obstacle part are recovered, and life can be taken care of oneself);Invalid (limbs disturbance, language function obstacle are unchanged, can't take care of oneself).3. result：As a result fall ill 30 days in 35, wherein：Effective 28 (80%), take a turn for the better 7 (20%), invalid 0.Morbidity 31 ~ 90 days in 65, wherein：Effective 48 (73.85%), take a turn for the better 12 (18.46%), invalid 5 (7.69%).Morbidity 91 ~ 180 days 221, wherein：Effective 125 (56.56%), take a turn for the better 52 (23.53%), invalid 44 (19.91%).
Goal of the invention：Hyperxia medical fluids therapeutic instrument intravenous fluids oxygen supply technology can make blood capillary open quantity to be increased, single arteriole blood flow rate is accelerated, ensure the hemoperfusion of ischemic tissue, and make the poikilocyte caused by ischemia injury return to normal condition, improve the mobility of cell membrane, the leukocyte of activation, platelet is made to tend to stable state, thrombosis are loosened or are reduced, intracellular respiratory function can be improved simultaneously, the activity of brain tissue cell Na, K-ATP enzyme is made to be able to recover or be close to the foundation for normally promoting the recovery and Doppler flow mapping of function of brain cell.Additionally, the technology can significantly improve the level of the superoxide dismutase of acute cerebral infarction patients, infringement of the free radical to brain is reduced, and it is convenient and easy, without obvious contraindication and complication.Therefore, the technology treatment efficacy of acute cerebral infarction significantly, using safety, possesses extensive clinical practice scene.
Technical scheme：Base fluid after the process of GY-1 type hyperxia medical fluids therapeutic instrument, with 5%GS liquid 250ml (the high person's normal saline of blood glucose), through hyperoxia instrument flow be 4L/min process after high-concentration oxygen fill it is molten after, add XUESAITONG ZHUSHEYE 400mg, intravenous drip, PaO2 rises to 100 ~ 120kPa by 21kPa, combine the input of corresponding Chinese medicine extract (Shu Xue-tong, XUESAITONG, Herba Erigerontiss etc.) vein again, one time a day, 10 1 courses for the treatment of, general treatment phase are 2 ~ 3 courses for the treatment of.Cerebral infarction and diabetic cerebrovascular disease are become and all obtains good therapeutic effect.Mitigating cardiovascular and cerebrovascular vessel ischemia symptom, help functional recovery of paralyzed limb and quality etc. of making the life better has obvious effect, there is preferably improvement to the microcirculation disturbance that extremity macroangiopathy and microangiopathies cause, cerebral infarction and diabetic cerebrovascular disease are become curative effect certainly.
Invention beneficial effect：Patients with Acute Cerebral Infarction case therapeutic effect is good compared with chronic phase case, receives treatment after morbidity in 6 months, and its effective percentage is 56.56%, receives treatment after morbidity in 3 months, and its effective percentage is 73.84%, receives treatment after morbidity in 1 month, and its effective percentage is 80%.
Preferred forms：Drug therapy is carried out to patient.
Innovation：This new patent of invention is related to a kind of method that hyperoxia Medical liquid treats cerebral infarction, hyperxia medical fluids therapeutic instrument intravenous fluids oxygen supply technology can make blood capillary open quantity to be increased, single arteriole blood flow rate is accelerated, ensure the hemoperfusion of ischemic tissue, and make the poikilocyte caused by ischemia injury return to normal condition, improve the mobility of cell membrane, make the leukocyte of activation, platelet tends to stable state, thrombosis are loosened or are reduced, intracellular respiratory function can be improved simultaneously, make brain tissue cell Na, the activity of K-ATP enzymes is able to recover or be close to normally, promote the recovery of function of brain cell and the foundation of Doppler flow mapping.Additionally, the technology can significantly improve the level of the superoxide dismutase of acute cerebral infarction patients, infringement of the free radical to brain is reduced, and it is convenient and easy, without obvious contraindication and complication.Therefore, the technology treatment efficacy of acute cerebral infarction significantly, using safety, possesses extensive clinical practice scene.
Claims (1)
1. a kind of method that hyperoxia Medical liquid treats cerebral infarction, base fluid of the method after the process of GY-1 type hyperxia medical fluids therapeutic instrument, PaO2 rises to 100 ~ 120kPa by 21kPa, combine the input of corresponding Chinese medicine extract (Shu Xue-tong, XUESAITONG, Herba Erigerontiss etc.) vein again, one time a day, 10 1 courses for the treatment of, general treatment phase are 2 ~ 3 courses for the treatment of；Hyperxia medical fluids vein treatment, cerebral infarction and diabetic cerebrovascular disease are become curative effect certainly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510596837.1A CN106539819A (en) | 2015-09-18 | 2015-09-18 | A kind of method that hyperoxia Medical liquid treats cerebral infarction |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510596837.1A CN106539819A (en) | 2015-09-18 | 2015-09-18 | A kind of method that hyperoxia Medical liquid treats cerebral infarction |
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| CN106539819A true CN106539819A (en) | 2017-03-29 |
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| CN201510596837.1A Pending CN106539819A (en) | 2015-09-18 | 2015-09-18 | A kind of method that hyperoxia Medical liquid treats cerebral infarction |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021536447A (en) * | 2018-08-31 | 2021-12-27 | レヴァレシオ・コーポレーション | Methods and Compositions for Treating Stroke |
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2015
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021536447A (en) * | 2018-08-31 | 2021-12-27 | レヴァレシオ・コーポレーション | Methods and Compositions for Treating Stroke |
| EP3843673A4 (en) * | 2018-08-31 | 2022-06-15 | Revalesio Corporation | Methods and compositions for treating stroke |
| JP7486474B2 (en) | 2018-08-31 | 2024-05-17 | レヴァレシオ・コーポレーション | Methods and Compositions for Treating Stroke |
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Application publication date: 20170329 |
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| WD01 | Invention patent application deemed withdrawn after publication |