CN106520538A - Isothermal chain multiple-detection card of pathogen nucleic acid - Google Patents
Isothermal chain multiple-detection card of pathogen nucleic acid Download PDFInfo
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- CN106520538A CN106520538A CN201611014943.5A CN201611014943A CN106520538A CN 106520538 A CN106520538 A CN 106520538A CN 201611014943 A CN201611014943 A CN 201611014943A CN 106520538 A CN106520538 A CN 106520538A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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Abstract
The invention discloses an isothermal chain multiple-detection card of pathogen nucleic acid. The isothermal chain multiple-detection card comprises a device main body, wherein a handheld device is arranged at one end of the device main body; an information processing device is arranged at one end of an inner cavity of the device main body; sliding devices are arranged at both ends of the inner wall of the device main body; the sliding devices are provided with connecting devices by virtue of sliding blocks; an adjusting device is arranged at one end of each connecting device; an extension bar is arranged at one end of the adjusting device and one end of the extension bar extends to the outer side of the device main body; a sucking device is arranged at one end of the extension bar; a detection device is arranged in an inner cavity of the extension bar and the detection device is connected to the sucking device; and a control device is arranged in an inner cavity of the device main body. The isothermal chain multiple-detection card provided by the invention is simple to use and convenient to use, and the isothermal chain multiple-detection card can facilitate users, so that good convenience is guaranteed when the isothermal chain multiple-detection card is used by the users.
Description
Technical field
A kind of the present invention relates to pathogen detection technical field, more particularly to the isothermal chain Multiple detection of pathogen nucleic acid
Card.
Background technology
Diagnostic nucleic acid is the theory and technology with molecular biology, by directly detecting existence or the defect of nucleic acid,
The function of nucleic acid is analyzed from nucleic acid structure, duplication, transcription or translation skill, so as to make the side of diagnosis to body state and disease
Method.Its target molecule is DNA or RNA, reflects the 26S Proteasome Structure and Function of nucleic acid.The gene of detection has endogenouss（That is body itself
Gene）With it is exogenous（Such as virus, antibacterial etc.）Two kinds, the former whether there is pathological changes for diagnostic gene, and the latter is whether there is for diagnosis
Pathogenic infection.The lab construction that cma gene based on molecular pathology is sequenced in medical institutions is still very weak, and which is former
Therefore one be clinical pathology gene diagnosises operating technology it is complicated, Knowledge Base is not enough, can to a great extent automatically, accurately
Complete tens thousand of kinds of different types of gene sequencing, abrupt climatic changes.Morphological diagnosiss gold of the clinical gene sequencing detection to Pathology Deparment
The lifting of standard gold content and the exploitation of molecular pathology technology and economic benefit improve realistic meaning.More than 2 years, we complete
The detection of totally 1 100 of more than ten kinds of pathological gene sequencing and fragment analysis, knows from experience as follows：Tissue and blood DNA are extracted successfully
Rate 100%, paraffin specimen extract success rate 80% first, and key link is, from DNA extraction agent boxes, to be fixed with neutral formalin
Time<48 h, abundant eluting formaldehyde and digestion are thoroughly；As a result show that baseline is smooth.Sequencing quality key control point：Template DNA matter
Amount will height；PCR requires that band is single, but copy number is less demanding；PCR primer must be after purification process, sequencing reaction
Recommend with ethanol/NaAc method repuritys；Electrophoresis capillary needs periodic maintenance and encapsulating；By detecting the sequence of tumor and related gene
Row, sum up following points clinical application significance during development gene sequencing project is examined outside pathology：For suspicious precancerous lesion
Whether really patient can specify the mutation containing candidate gene of its pathological changes specimen, a large amount of by immunohistochemical markers cancer base to release
Because the psychology of positive patient is panic and financial burden.The lymphatic metastasiss for reflecting are failed to pathological section plane local, by complete
Lymph node tissue DNA colloidal sol KRAS oncogenes are sequenced, the clinical micrometastasis phenomenon of auxiliary detection.Identification cardiovascular and cerebrovascular disease APOE bases
Because of 6 kinds of gene phenotypes of polymorphism, 4 high-risk types of ε are relevant with hyperlipemia, coronary heart disease, cerebrovascular and alzheimer disease.To cancer
Relatives' detection Related oncogene mutation or polymorphism that disease family has relationship by blood, with subhealth state diagnosis and health check-up meaning.
Drug resistance of the YMDD abrupt climatic changes hepatitis B virus to lamivudine.
But existing detection is stuck in when carrying out the isothermal chain of pathogen nucleic acid and detecting, it is impossible to enough have one it is well stable
Property and Multiple detection effect, inconvenience effectively detected with user, it is impossible to reach pathogen is carried out effectively from many aspects
Detection so that user causes user wasting using process easy-to-use well using process neither one
The many time and efforts of user.
The content of the invention
The invention aims to shortcoming present in prior art is solved, and a kind of pathogen nucleic acid for proposing etc.
Warm chain Multiple detection card.
To achieve these goals, present invention employs following technical scheme：
A kind of isothermal chain multiple detection card of pathogen nucleic acid, including apparatus main body, one end of described device main body is provided with hand-held
Device, inner chamber one end of described device main body are provided with information processor, and the inwall two ends of described device main body are equipped with slip
Device, the carriage are provided with attachment means by slide block, and one end of the attachment means is provided with adjusting means, the tune
One end of regulating device is provided with extension rod, and extends the outside that one end of rod extends to apparatus main body, one end of the extension rod
Suction means is provided with, the inner chamber of the extension rod is provided with detection means, and detection means is connected with suction means, described device
The inner chamber of main body is provided with control device, and the control device is electric with carriage, information processor and detection means respectively
Property connection.
Preferably, the inner chamber of described device main body is provided with Minisize electricity storage device, and the outer end side of apparatus main body is provided with
Charging device, the charging device are electrically connected with Minisize electricity storage device.
Preferably, the outer end side of described device main body is provided with control panel, and the control panel is electrical with control device
Connection.
Preferably, the outer end of the hand-held device is provided with anti-slip veins, and the side of hand-held device is provided with display device, described
Display device is electrically connected with control device.
Preferably, the detection means is electrically connected with information processor.
In the present invention, by way of being detected using telescopic multiple so that user can be good at using process
Used and operated, be easy to user to carry out more many detections to the isothermal chain of pathogen nucleic acid, increase the complete of detection
Face property so that user can have a good using effect using process, offer convenience to user so that user
There can be a good using effect using process, increase the easy-to-use of device, the device is having one using process
Operability, is easy to user to be operated and used so that user more can be being facilitated using process, effectively well
The time and efforts of user is saved.
Description of the drawings
Fig. 1 is a kind of structural representation of the isothermal chain multiple detection card of pathogen nucleic acid proposed by the present invention.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.
With reference to Fig. 1, a kind of isothermal chain multiple detection card of pathogen nucleic acid, including apparatus main body 4, the one of apparatus main body 4
End is provided with hand-held device 1, and inner chamber one end of apparatus main body 4 is provided with information processor 2, and the inwall two ends of apparatus main body 4 are all provided with
There is carriage 3, carriage 3 is provided with attachment means 6 by slide block 5, and one end of attachment means 6 is provided with adjusting means 7, adjust
One end of regulating device 7 is provided with extension rod 8, and extends the outside that one end of rod 8 extends to apparatus main body 4, extends one end of rod 8
Suction means 10 is provided with, the inner chamber for extending rod 8 is provided with detection means 9, and detection means 9 is connected with suction means 10, device
The inner chamber of main body 4 is provided with control device, and control device is electric with carriage 3, information processor 2 and detection means 9 respectively
Property connection, the inner chamber of apparatus main body 4 is provided with Minisize electricity storage device, and the outer end side of apparatus main body 4 is provided with charging device, fills
Electric installation is electrically connected with Minisize electricity storage device, and the outer end side of apparatus main body 4 is provided with control panel, control panel and control dress
Put electric connection, the outer end of hand-held device 1 is provided with anti-slip veins, and the side of hand-held device be provided with display device, display device with
Control device is electrically connected with, and detection means 9 is electrically connected with information processor 2.The present invention is using simple, install convenient, side
Just user is used so that user is having a good convenience using process.
The present invention is by way of being detected using telescopic multiple so that user can be good at carrying out using process
Use and operate, be easy to user to carry out more many detections to the isothermal chain of pathogen nucleic acid, increase the comprehensive of detection,
Enable user having a good using effect using process, offer convenience to user so that user makes
There can be a good using effect with process, increase the easy-to-use of device, the device is having one very well using process
Operability, be easy to user to be operated and used so that user is effectively saved more being facilitated using process
The time and efforts of user.
The above, the only present invention preferably specific embodiment, but protection scope of the present invention is not limited thereto,
Any those familiar with the art the invention discloses technical scope in, technology according to the present invention scheme and its
Inventive concept equivalent or change in addition, should all be included within the scope of the present invention.
Claims (5)
1. a kind of isothermal chain multiple detection card of pathogen nucleic acid, including apparatus main body（4）, it is characterised in that described device master
Body（4）One end be provided with hand-held device（1）, described device main body（4）Inner chamber one end be provided with information processor（2）, it is described
Apparatus main body（4）Inwall two ends be equipped with carriage（3）, the carriage（3）By slide block（5）Connection dress is installed
Put（6）, the attachment means（6）One end be provided with adjusting means（7）, the adjusting means（7）One end extension rod is installed
（8）, and extend rod（8）One end extend to apparatus main body（4）Outside, the extension rod（8）One end be provided with suction means
（10）, the extension rod（8）Inner chamber detection means is installed（9）, and detection means（9）With suction means（10）Connection, institute
State apparatus main body（4）Inner chamber control device is installed, the control device respectively with carriage（3）, information processor
（2）And detection means（9）It is electrically connected with.
2. a kind of isothermal chain multiple detection card of pathogen nucleic acid according to claim 1, it is characterised in that described device
Main body（4）Inner chamber Minisize electricity storage device, and apparatus main body are installed（4）Outer end side be provided with charging device, the charging
Device is electrically connected with Minisize electricity storage device.
3. a kind of isothermal chain multiple detection card of pathogen nucleic acid according to claim 1, it is characterised in that described device
Main body（4）Outer end side be provided with control panel, the control panel is electrically connected with control device.
4. the isothermal chain multiple detection card of a kind of pathogen nucleic acid according to claim 1, it is characterised in that described hand-held
Device（1）Outer end be provided with anti-slip veins, and the side of hand-held device is provided with display device, the display device and control device electricity
Property connection.
5. a kind of isothermal chain multiple detection card of pathogen nucleic acid according to claim 1, it is characterised in that the detection
Device（9）With information processor（2）It is electrically connected with.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611014943.5A CN106520538A (en) | 2016-11-18 | 2016-11-18 | Isothermal chain multiple-detection card of pathogen nucleic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611014943.5A CN106520538A (en) | 2016-11-18 | 2016-11-18 | Isothermal chain multiple-detection card of pathogen nucleic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106520538A true CN106520538A (en) | 2017-03-22 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611014943.5A Pending CN106520538A (en) | 2016-11-18 | 2016-11-18 | Isothermal chain multiple-detection card of pathogen nucleic acid |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102230032A (en) * | 2011-06-27 | 2011-11-02 | 广州弗赛生物科技有限公司 | Isothermal chain multiple detection card of pathogen nucleic acid |
| CN102612646A (en) * | 2009-10-21 | 2012-07-25 | 瑞士斯保德精密诊断有限公司 | Test device and method |
| CN204882369U (en) * | 2015-07-14 | 2015-12-16 | 天津亿朋医疗器械有限公司 | Blood detection device |
| CN205450000U (en) * | 2016-02-25 | 2016-08-10 | 杭州冰桶生物科技有限公司 | Pregnant excellent device is tested to electron |
| CN205450001U (en) * | 2016-02-25 | 2016-08-10 | 杭州冰桶生物科技有限公司 | Test pregnant excellent device |
| CN205643168U (en) * | 2015-12-28 | 2016-10-12 | 天津派普大业仪器科技有限公司 | Urine detection device for urine detection cloud computing system |
-
2016
- 2016-11-18 CN CN201611014943.5A patent/CN106520538A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102612646A (en) * | 2009-10-21 | 2012-07-25 | 瑞士斯保德精密诊断有限公司 | Test device and method |
| CN102230032A (en) * | 2011-06-27 | 2011-11-02 | 广州弗赛生物科技有限公司 | Isothermal chain multiple detection card of pathogen nucleic acid |
| CN204882369U (en) * | 2015-07-14 | 2015-12-16 | 天津亿朋医疗器械有限公司 | Blood detection device |
| CN205643168U (en) * | 2015-12-28 | 2016-10-12 | 天津派普大业仪器科技有限公司 | Urine detection device for urine detection cloud computing system |
| CN205450000U (en) * | 2016-02-25 | 2016-08-10 | 杭州冰桶生物科技有限公司 | Pregnant excellent device is tested to electron |
| CN205450001U (en) * | 2016-02-25 | 2016-08-10 | 杭州冰桶生物科技有限公司 | Test pregnant excellent device |
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Application publication date: 20170322 |
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