CN106511154A - Peach kernel extract and application thereof - Google Patents
Peach kernel extract and application thereof Download PDFInfo
- Publication number
- CN106511154A CN106511154A CN201610943438.2A CN201610943438A CN106511154A CN 106511154 A CN106511154 A CN 106511154A CN 201610943438 A CN201610943438 A CN 201610943438A CN 106511154 A CN106511154 A CN 106511154A
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- China
- Prior art keywords
- solution
- semen persicae
- extract
- petroleum ether
- gained
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses peach kernel extract, and relates to the field of natural medicinal chemistry and the field of cosmetics. The peach kernel extract is prepared from ethyl alcohol, petroleum ether and ethyl acetate through sequential extraction. The prepared extract has a very good moisture preserving effect, can provide a very good moisture preserving function for skin horn cells, and can also absorb energy of ultraviolet rays and release the energy in the form of heat energy or visible light, and damage of the ultraviolet rays to skin is reduced. The peach kernel extract can be used in the cosmetics, has the effects of preserving and locking moisture, resisting bacteria and preventing the ultraviolet rays and makes the skin shiny and glossier.
Description
Technical field
The present invention relates to field of natural medicinal chemistry and cosmetic field, and in particular to a kind of Semen Persicae extract and its should
With.
Background technology
Semen Persicae, Chinese medicine name.For rosaceous plant Fructus Persicae Prunus persica (L.) Batsch or Prunus davidiana Prunus
The dry mature seed of davidiana (Carr.) Franch..Harvest after fruit maturation, remove sarcocarp and nucleocapsid, take out seed,
Dry.Generally cultivate all parts of the country.With blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma.For amenorrhea dysmenorrhea, abdominal mass abdominal mass
Mass in the abdomen, lung abscess acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma.Semen Persicae is mainly used in Chinese drugs agentia field at present, fresh few
See which is used in moisturizing or sun-proof cosmetics.
The content of the invention
The present invention is intended to provide a kind of Semen Persicae extract and its application.
The present invention is achieved through the following technical solutions：
A kind of Semen Persicae extract, comprises the steps：
（1）Semen Persicae is carried out after roguing process, then puts it into water in boiling water scalding 2 ~ 3min, dried after taking-up naturally standby；
（2）By step（1）Semen Persicae after process crosses 80 mesh after crushing, and the mass fraction for then placing into 3 ~ 4 times of its gross mass is
In 85% ethanol solution, continuous 12 ~ 14h of backflow extraction filters to obtain lixiviating solution and filtering residue, then lixiviating solution is carried out alcohol and processes
It is standby that solution A is obtained afterwards；
（3）By step（2）The filtering residue of gained is put in the petroleum ether of 4 ~ 5 times of its gross mass, by petroleum ether after 8 ~ 10h of soak extraction
Extracting solution takes out, and then carries out petroleum ether to which and goes division operation, obtains solution B standby；
（4）By step（2）The solution A and step of gained（3）After the common mix homogeneously of solution B of gained, its equal-volume is added
Ethyl acetate, while carry out supersound process, after continuously extracting 30 ~ 40min, take supernatant.
Further, step（4）Described in supersound process when ultrasound power be 350W.
A kind of application of Semen Persicae extract, in the moisturizing or sun care preparationss for human body skin.
Further, the addition mass percent during which is used in moisturizing or sun care preparationss is 0.2 ~ 0.7%.
The present invention has the advantages that：
The present invention has carried out ethanol, petroleum ether, ethyl acetate extraction process successively to Semen Persicae, contains substantial amounts of oils and fatss in extract
The compositions such as class, glycoside, volatile oil, flavone, glucoside compound, amino acid and protein, take full advantage of material composition, are obtained
Extract have good moisture-keeping efficacy, can give skin keratinocytes good moisture-keeping function, can effectively absorb ultraviolet again
Energy, then with the forms such as heat energy or visible ray discharge, reduce damage of the ultraviolet to skin.After being added in cosmetics, tool
There is the effect of moisturizing water lock, antibacterial ultraviolet-resistannanofiber, make skin brilliance more moisten.
Specific embodiment
Embodiment 1
A kind of Semen Persicae extract, comprises the steps：
（1）Semen Persicae is carried out after roguing process, then puts it into water in boiling water scalding 2min, dried after taking-up naturally standby；
（2）By step（1）Semen Persicae after process crosses 80 mesh after crushing, and the mass fraction for then placing into 3 times of its gross mass is 85%
Ethanol solution in, continuous backflow extraction 12h filters to obtain lixiviating solution and filtering residue, then carries out after alcohol is processed molten by lixiviating solution
Liquid A is standby；
（3）By step（2）The filtering residue of gained is put in the petroleum ether of 4 times of its gross mass, by Petroleum ether extraction after soak extraction 8h
Liquid takes out, and then carries out petroleum ether to which and goes division operation, obtains solution B standby；
（4）By step（2）The solution A and step of gained（3）After the common mix homogeneously of solution B of gained, its equal-volume is added
Ethyl acetate, while carry out supersound process, it is continuous extract 30min after, take supernatant.
Further, step（4）Described in supersound process when ultrasound power be 350W.
In order to verify the moistening effect of extract of the present invention, moisturizing experiment is carried out, specially：Simulated skin state, selects
The microscope slide of 25.4 × 76.2mm, sticks 3M adhesive tapes, and the extract described in embodiment 1 is configured to certain density aqueous solution,
The sample of 180mg is weighed, by its uniform application on microscope slide, is put in the instrument of constant temperature and humidity.This experiment is in room temperature（25
℃）Under carry out, 80% constant humidity environment is controlled using saturated ammonium sulfate solution.Weigh after certain hour, calculate sample
Percentage of water loss, compares moistening effect by the size of percentage of water loss, and percentage of water loss is less to represent that moistening effect is better.Wherein percentage of water loss
（%）=（M2-M3）/（M2-M1）× 100%, M1 are microscope slide weight（g）, M2 is gross weight before placing after smearing（g）, M3 is to apply
Gross weight after placing after smearing（g）.Table 1 below between concrete data：
Table 1
As can be seen from the above table, the Semen Persicae extract of present invention gained has good moisture-keeping efficacy.
Embodiment 2
A kind of Semen Persicae extract, comprises the steps：
（1）Semen Persicae is carried out after roguing process, then puts it into water in boiling water scalding 3min, dried after taking-up naturally standby；
（2）By step（1）Semen Persicae after process crosses 80 mesh after crushing, and the mass fraction for then placing into 4 times of its gross mass is 85%
Ethanol solution in, continuous backflow extraction 14h filters to obtain lixiviating solution and filtering residue, then carries out after alcohol is processed molten by lixiviating solution
Liquid A is standby；
（3）By step（2）The filtering residue of gained is put in the petroleum ether of 5 times of its gross mass, by Petroleum ether extraction after soak extraction 10h
Liquid takes out, and then carries out petroleum ether to which and goes division operation, obtains solution B standby；
（4）By step（2）The solution A and step of gained（3）After the common mix homogeneously of solution B of gained, its equal-volume is added
Ethyl acetate, while carry out supersound process, it is continuous extract 40min after, take supernatant.
Further, step（4）Described in supersound process when ultrasound power be 350W.
In order to further verify the sun-proof result of extract of the present invention, sun-proof experiment is carried out, specially：Example 2 is made
1.0 mL of Semen Persicae extract for obtaining, is placed in 10mL color comparison tubes, is settled to scale with corresponding Extraction solvent, with reagent blank as ginseng
Than using UV-2550 ultraviolet-uisible spectrophotometers (Japanese Shimadzu Corporation produces), determining its ultra-violet absorption spectrum, calculating respectively
200,210,220,230,240,250,260,270,280 nms of the extract in UVC (200 ~ 280nm) area, UVB (280 ~
320 nm) area 280,290,300,310,320 nm and UVA (320 ~ 400 nm) area 320,330,340,350,360,
370th, the mean absorbance values of 380,390,400 nm, evaluate the i.e. sun-proof performance of its ultra-violet absorption, and concrete data see the table below 2：
Table 2
| UVC areas absorbance（A） | UVB areas absorbance（A） | UVA areas absorbance（A） | |
| Semen Persicae extract | 0.685 | 0.826 | 0.554 |
By upper table 2 as can be seen that extract of the present invention has good sun-proof result.
Claims (4)
1. a kind of Semen Persicae extract, it is characterised in that comprise the steps：
（1）Semen Persicae is carried out after roguing process, then puts it into water in boiling water scalding 2 ~ 3min, dried after taking-up naturally standby；
（2）By step（1）Semen Persicae after process crosses 80 mesh after crushing, and the mass fraction for then placing into 3 ~ 4 times of its gross mass is
In 85% ethanol solution, continuous 12 ~ 14h of backflow extraction filters to obtain lixiviating solution and filtering residue, then lixiviating solution is carried out alcohol and processes
It is standby that solution A is obtained afterwards；
（3）By step（2）The filtering residue of gained is put in the petroleum ether of 4 ~ 5 times of its gross mass, by petroleum ether after 8 ~ 10h of soak extraction
Extracting solution takes out, and then carries out petroleum ether to which and goes division operation, obtains solution B standby；
（4）By step（2）The solution A and step of gained（3）After the common mix homogeneously of solution B of gained, its equal-volume is added
Ethyl acetate, while carry out supersound process, after continuously extracting 30 ~ 40min, take supernatant.
2. a kind of Semen Persicae extract according to claim 1, it is characterised in that step（4）Described in supersound process when
The power of ultrasound is 350W.
3. a kind of application of Semen Persicae extract as claimed in claim 1 or 2, it is characterised in that for the moisturizing of human body skin
Or in sun care preparationss.
4. the application of a kind of Semen Persicae extract according to claim 3, it is characterised in which is used in moisturizing or sun-proof cosmetic
Addition mass percent in product is 0.2 ~ 0.7%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610943438.2A CN106511154A (en) | 2016-10-24 | 2016-10-24 | Peach kernel extract and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610943438.2A CN106511154A (en) | 2016-10-24 | 2016-10-24 | Peach kernel extract and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106511154A true CN106511154A (en) | 2017-03-22 |
Family
ID=58293297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610943438.2A Pending CN106511154A (en) | 2016-10-24 | 2016-10-24 | Peach kernel extract and application thereof |
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| Country | Link |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3070862A1 (en) * | 2017-09-14 | 2019-03-15 | Quanshen Liu | SKIN WHITENING AND SOLAR PROTECTION COMPOSITION COMPRISING NANO MATERIALS AND EXTRACT FROM CHINESE MEDICINE |
| CN112587710A (en) * | 2021-02-05 | 2021-04-02 | 甘肃省分析测试中心 | Preparation process and application of peach kernel extract core-shell nano-structure film |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631306A (en) * | 2012-01-09 | 2012-08-15 | 杭州万承志堂国药馆有限公司 | Freckle removing and skin whitening mask containing traditional Chinese medicines |
| CN105461765A (en) * | 2015-11-25 | 2016-04-06 | 江苏康缘药业股份有限公司 | Preparation method of amygdalin |
-
2016
- 2016-10-24 CN CN201610943438.2A patent/CN106511154A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102631306A (en) * | 2012-01-09 | 2012-08-15 | 杭州万承志堂国药馆有限公司 | Freckle removing and skin whitening mask containing traditional Chinese medicines |
| CN105461765A (en) * | 2015-11-25 | 2016-04-06 | 江苏康缘药业股份有限公司 | Preparation method of amygdalin |
Non-Patent Citations (1)
| Title |
|---|
| 吴兆宇，等: ""桃仁中苦杏仁苷及多糖的闪式提取工艺"", 《中成药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3070862A1 (en) * | 2017-09-14 | 2019-03-15 | Quanshen Liu | SKIN WHITENING AND SOLAR PROTECTION COMPOSITION COMPRISING NANO MATERIALS AND EXTRACT FROM CHINESE MEDICINE |
| CN112587710A (en) * | 2021-02-05 | 2021-04-02 | 甘肃省分析测试中心 | Preparation process and application of peach kernel extract core-shell nano-structure film |
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Application publication date: 20170322 |