CN106510613B - Optical phase delay device for axiallength measurement - Google Patents
Optical phase delay device for axiallength measurement Download PDFInfo
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- CN106510613B CN106510613B CN201611096046.3A CN201611096046A CN106510613B CN 106510613 B CN106510613 B CN 106510613B CN 201611096046 A CN201611096046 A CN 201611096046A CN 106510613 B CN106510613 B CN 106510613B
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- 230000003287 optical effect Effects 0.000 title claims abstract description 39
- 230000004323 axial length Effects 0.000 title claims abstract description 18
- 238000005259 measurement Methods 0.000 title claims abstract description 18
- 230000033001 locomotion Effects 0.000 claims abstract description 11
- 210000001508 eye Anatomy 0.000 claims description 9
- 238000006073 displacement reaction Methods 0.000 claims description 8
- 241000826860 Trapezium Species 0.000 claims description 3
- 230000035772 mutation Effects 0.000 claims description 2
- 238000010408 sweeping Methods 0.000 claims description 2
- 230000001154 acute effect Effects 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000010276 construction Methods 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 3
- 239000006185 dispersion Substances 0.000 description 6
- 239000000523 sample Substances 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 210000004087 cornea Anatomy 0.000 description 2
- 238000005305 interferometry Methods 0.000 description 2
- 238000012014 optical coherence tomography Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000005252 bulbus oculi Anatomy 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000005304 optical glass Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/102—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for optical coherence tomography [OCT]
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Eye Examination Apparatus (AREA)
Abstract
The present invention relates to a kind of optical phase delay device for axiallength measurement,Including fixed first right-angle prism and two transportable right-angle prisms,Second and the 3rd right-angle prism mounted on top on translation stage,Translation stage is motor driven movement,Make second and the 3rd right-angle prism synchronizing moving,The hypotenuse of three right-angle prisms all has identical angle,The hypotenuse of three right-angle prisms is set point-blank to be bonded,After source light is by the incidence of the right-angle side of the second right-angle prism or the 3rd right-angle prism and passing through,The right-angle side of the first right-angle prism is impinged perpendicularly on by the first right-angle prism hypotenuse,Backtracking after the highly reflecting films reflection plated again on the right-angle side of the first right-angle prism,Light source is motionless,Translation stage moves,In moving process light incide on two right-angle prisms produce range difference realize phase delay.Linear scan;Aberrationless introduces;It is simple in construction;Cost is low;Realize the full eye scanning of anterior ocular segment and oculi posterior segment.
Description
Technical field
The present invention relates to a kind of medical optical instrument, more particularly to a kind of optical phase put-off for axiallength measurement
Device.
Background technology
The measurement of axiallength is that the principle based on the interference of light either ultrasound detection, interference of light method can realize non-connect
Touch, high-resolution and it is quick the features such as, and ultrasonic power need contact eyes, resolution ratio is low, and ultrasonic probe is that have pressure to eye
Eyeball can all cause the precision of measurement result not ensure.In interference of light method, using partially coherent or low coherence interference technology, light
Source, which uses, the good light source of the spatial coherence of certain bandwidth, in terms of interferometry, reference arm and the optics position phase of sample arm
Interference can be just realized in the coherence length less than light source.In order to realize the measurement of axiallength, it is necessary to one axially
The optical phase put-off line of scanning, matching reference arm differ the phase less than light source with the position from sample different depth in sample arm
Dry length, realize the interference signal collection by cornea to eye ground.
In optical coherence tomography system, the axial optical phase put-off line reported at present includes:1st, linear translation
Speculum, it is most simply also most long axial scan mode that this, which is,;The defects of simple in construction, cost is low, but main is volume
Greatly, working line is grown, and stability is influenceed by mechanical structure;2nd, piezoelectricity control parallel mirror;Dependable performance, stability
Height, but price is high, scanning range is limited, the axiallength measurement for the scope that is not suitable for exposing thoroughly;3rd, swept using revolving cube
Retouch mode;The scope that exposes thoroughly can be realized using the scanning of this mode, but installation and debugging are difficult, and scanning be not it is linear,
There are dispersion, dutycycle low, it is necessary to which algorithm coordinates;4th, rotational micromirror array, mission nonlinear, have dispersion, have certain dutycycle,
Capacity usage ratio is low, regulation is excessively complicated, and cost is high, is not suitable for high-volume industrialization.5th, involute spiral mirror;Height can be realized
The advantages that speed, good linearity, regulation are simple, the scope that exposes thoroughly, non-dispersive, but make that required precision is too high, is difficult practical.It is existing
Stage, widely used was by the binary channels of the Fujimoto groups proposition of america's MIT in the reference arm of TD-OCT systems
Rapid scanning delay line (Double pass rapid scanning optical delay line, RSOD), passes through
The Phase and group velocities of optical grating diffraction effect independent control scanning, are provided simultaneously with dispersion adjustment ability.System architecture is complicated, member
The problems such as part is more, and debugging is difficult, and cost is high.
The content of the invention
The problem of existing the present invention be directed to axial optical phase put-off line, it is proposed that a kind of to be used for what axiallength measured
Optical phase delay device, axiallength is measured based on optics low coherence interference principle, i.e., by the geometrical length of cornea to retina,
Need the device of a phase delay or axial scan, using the principle of phase compensation in interferometry devise variable phase or
The delayer of axiallength measurement, the present invention is in the fixed bit phase delay 2 of setting(n-1)In the case of s, can with it is before eyes section and
Oculi posterior segment scans, and realizes the scanning of full eye.
The technical scheme is that:A kind of optical phase delay device for axiallength measurement, including it is fixed
The first right-angle prism and two transportable second and the 3rd right-angle prism, second and the 3rd right-angle prism mounted on top position
In on a translation stage, translation stage is motor driven movement, makes second and the 3rd right-angle prism synchronizing moving, the 3rd right-angle prism
For right-angled trapezium prism, the second right-angle prism is right angled triangle, and the hypotenuse of three right-angle prisms all has identical angle, made
The hypotenuses of three right-angle prisms be point-blank bonded, as fitting side, as translation stage moves, second and the 3rd right angle
Prism can move along fitting side, and source light is incident by the right-angle side of the second right-angle prism or the 3rd right-angle prism and passes through
Afterwards, the right-angle side of the first right-angle prism, then the right angle by the first right-angle prism are impinged perpendicularly on by the first right-angle prism hypotenuse
Backtracking after the highly reflecting films reflection plated on side, light source is motionless, and translation stage movement, light incides the second right-angle prism right angle
On side and the range difference that incides on the 3rd right-angle prism right-angle side is s.
The refractive index of three right-angle prisms is identical.
Described second and the 3rd movable length of the right-angle prism incidence right-angle side under electrode drive be L, right-angle prism
Refractive index is n, air refraction n0, the second right-angle prism right-angle side is with the angle for being bonded sidea, that is, it is coated with high reflection
First right-angle prism right-angle side of film is with the angle for being bonded sidea, then the optical phase delay device is in translation stage motion scan
When total optics optical path difference be:
。
The beneficial effects of the present invention are:The present invention is used for the optical phase delay device of axiallength measurement, scan mode
To be linear;It is simple in construction;Cost is low;And the scope of required scanning is small, speed is fast;After very advantageously realizing anterior ocular segment and eye
The full eye scanning of section;Two prisms constitute an optical flat, collimated ray vertical incidence, and aberrationless introduces;Meanwhile prism
Using low dispersion, optical glass having high refractive index, the influence of system dispersion is eliminated, high index of refraction can reduce sweep length and can
To realize large area scanning.
Brief description of the drawings
Fig. 1 is the optical phase delay device structural representation that the present invention is used for axiallength measurement;
Fig. 2 is two right-angle prism geometrical relationship figures in optical phase delay device of the present invention.
Embodiment
In order to realize high stability, expose thoroughly scope, the purpose of quick axiallength measurement, is prolonged using prism axial direction optics
Slow technology realizes the quick scanning of anterior ocular segment and oculi posterior segment, finally realizes that axiallength measures;Specific measures for implementation are:Such as figure
Optical phase delay device structural representation shown in 1, axial scan optical delay line is by fixed big right-angle prism 1 and can be with
Mobile right-angle prism 2 and 3 forms;The mounted on top of right-angle prism 2 and 3 is on a translation stage 5, by translation stage 5 in motor 6
Make the synchronizing moving of right-angle prism 2 and 3 under driving;Right-angle prism 3 is by square or rectangular right-angle prism, and it is small straight to remove part
The arm of angle, formed while being bonded with the hypotenuse of triangular right-angle prism 2 or being directly processed into the right-angle prism of right-angled trapezium, three straight
The hypotenuse of angle prism all has identical angle so that the hypotenuse of three right-angle prisms is point-blank bonded, dotted line in Fig. 1
To be bonded side, as translation stage 5 moves, right-angle prism 2 and 3 can move along fitting side;Source light by right-angle prism 2 or
The right-angle side of right-angle prism 1 is impinged perpendicularly on after the right-angle side incidence of right-angle prism 3, then is plated on the right-angle side of right-angle prism 1
Highly reflecting films 4 reflect after backtracking original optical path.The geometrical relationship figure of two right-angle prisms 2 and 3 as shown in Figure 2, right-angle prism 2
It is with the angle for being bonded sidea, and the right-angle side of right-angle prism 1 for being coated with highly reflecting films 4 and the angle for being bonded side, light source is motionless,
Translation stage 5 moves, and it is s that light, which incides the range difference on the right-angle side of right-angle prism 2 and incided on the right-angle side of right-angle prism 3,
In the translation motion of right-angle prism 2 and 3, what the variable quantity of caused axial scan depth or optics position phase can be as shown in Figure 2
Relation is calculated.
If motor driving translational movement is L;Light source incidence since the incident right-angle side summit of right-angle prism 2, mobile translation stage
5,2 incident right-angle side of light source opposing right angles prism is moved down into the base of 3 incident right-angle side of right-angle prism from summit, then axial light
Phase-delay quantity is learned to may be calculated:
Wherein, n is the refractive index of three right-angle prisms(The refractive index of three right-angle prisms is identical), n0For air refraction
Rate, generally 1;From axial optics optical path difference phase delay calculating formula of length, optics optical path difference is put down with motor-driven
Shifting amount L is in direct ratio, axial optical phase put-off in this way be linear change, displacement motor is set in systems
L measurement sensors are measured, as long as the numerical value can for measuring L linearly corresponds to axial optical path difference;This displacement transducer can select
With magnetic grid displacement transducer, grating displacement sensor can also be selected, the resolution ratio of sensor is better than 10um.Right-angle prism 2 and 3
For a special optical texture, i.e. it is s that the incident right-angle side of right-angle prism 2 and 3, which has a range difference,;The advantages of this spline structure
Be, incident ray from the right-angle side of right-angle prism 2 be transitioned into 3 right-angle side of right-angle prism when, in axial scan, optics optical path difference has
Individual mutation, 2 (n-1) s, scanning range so can directly be jumped to the scope on eyeground from anterior ocular segment, in other words right angle
Prism 2 can be used for the axial scan of anterior ocular segment, and right-angle prism 3 directly arrives optical phase put-off across the vitreum in eyes
Eye ground, realize the measurement of full axiallength.The foundation so designed is exactly the vitreum between anterior ocular segment and oculi posterior segment
Length be about 16mm, the tissue on this segment distance is optically considered uniform, without any interface, so complete in scanning
The direct surface sweeping oculi posterior segment in this part can be at the moment skipped, oculi posterior segment optics optical path difference total when scanning may be calculated:
In the making of all prisms, glass uses high index of refraction, the material of low dispersion.System non-dispersive is so can guarantee that,
And scanning range can be smaller.
Claims (1)
1. a kind of optical phase delay device for axiallength measurement, it is characterised in that including fixed first right angle
Prism and two transportable second and the 3rd right-angle prism, second and the 3rd right-angle prism mounted on top positioned at one translation
On platform, translation stage is motor driven movement, makes second and the 3rd right-angle prism synchronizing moving, the 3rd right-angle prism is right-angled trapezium
Prism, the first and second right-angle prisms are right-angled triangular prism, and in structure, the second right-angle prism overlays the 3rd right-angle prism
On make hypotenuse conllinear, the first right-angle prism hypotenuse is more than conllinear hypotenuse, and is bonded conllinear hypotenuse, three right-angle prisms after fitting
Right-angle side is parallel two-by-two, as conllinear hypotenuse is bonded, as translation stage moves, second and the 3rd right-angle prism can be along fitting altogether
Line hypotenuse moves, and source light is incident by the right-angle side of the second right-angle prism or the 3rd right-angle prism and after passing through, by the
One right-angle prism hypotenuse impinges perpendicularly on the right-angle side of the first right-angle prism, then the height plated on the right-angle side of the first right-angle prism
Backtracking after reflectance coating reflection, light source is motionless, translation stage movement, if motor driving translational movement is L;Light source is from the second right-angled edge
Mirror incidence right-angle side summit starts incidence, mobile translation stage, makes light source with respect to the second right-angle prism incidence right-angle side under summit
The base of the 3rd right-angle prism incidence right-angle side is moved on to, then axial optical phase put-off amount may be calculated:
Wherein, n is the refractive index of three right-angle prisms, and the refractive index of three right-angle prisms is identical, n0For air refraction,aFor
Angle of the two right-angle prism incidence right-angle sides with being bonded conllinear hypotenuse, it is coated with the first right-angle prism right-angle side and patch of highly reflecting films
Amount to the angle of line hypotenuse withaIt is equal, the acute angle and 90 on the conllinear hypotenuse of fitting of the 3rd right-angle prism°- aIt is equal;
From axial optical phase put-off amount calculation formula, axial optical phase put-off amount and motor-driven translational movement L into
Direct proportion, axial optical phase put-off amount are linear change, set the displacement of the translational movement L of motor measurement to pass in systems
Sensor, as long as the numerical value can for measuring L linearly corresponds to axial optical phase put-off amount;Displacement transducer selects magnetic grid position
Displacement sensor or grating displacement sensor, the resolution ratio of sensor are better than 10 μm;
Second and the 3rd right-angle prism be a special optical texture, i.e., second and the 3rd the incident right-angle side of right-angle prism have
One range difference is s;Incident ray from the second right-angle prism right-angle side be transitioned into the 3rd right-angle prism right-angle side when, in axial scan
When axial direction optical phase put-off amount have 2 (n-1) s of mutation, so scanning range directly can be jumped to eyeground from anterior ocular segment
Scope, in other words the second right-angle prism can be used for the axial scan of anterior ocular segment, the 3rd right-angle prism is across in eyes
Vitreum directly by axial optical phase put-off to eye ground, realize the measurement of full axiallength;
The length that the foundation of design is exactly the vitreum between anterior ocular segment and oculi posterior segment is about 16mm, being organized on this segment distance
Optically it is considered uniform, without any interface, so the direct surface sweeping oculi posterior segment in this part can be at the moment skipped entirely in scanning,
Total axial optical phase put-off amount may be calculated when oculi posterior segment scans:
。
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Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0433008A2 (en) * | 1989-12-11 | 1991-06-19 | Konica Corporation | Laser interferometric measuring apparatus |
CN201212838Y (en) * | 2008-07-16 | 2009-03-25 | 中国科学院上海光学精密机械研究所 | Space phase shifter for synchronous phase-shifting interferometer |
CN103256991A (en) * | 2013-05-08 | 2013-08-21 | 中国科学院上海光学精密机械研究所 | Spatial phase shift lateral shearing interferometer |
CN204129323U (en) * | 2014-08-06 | 2015-01-28 | 张建平 | The total-reflection type prism assemblies of digital micro mirror projection light engine |
CN204909391U (en) * | 2015-07-24 | 2015-12-30 | 广东福地新视野光电技术有限公司 | OCT reference arm structure and OCT imaging system |
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JP5168973B2 (en) * | 2007-03-27 | 2013-03-27 | 横河電機株式会社 | Interferometer, demodulator and branch element |
JP5588769B2 (en) * | 2010-07-01 | 2014-09-10 | 株式会社 光コム | Optical measuring device |
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Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0433008A2 (en) * | 1989-12-11 | 1991-06-19 | Konica Corporation | Laser interferometric measuring apparatus |
CN201212838Y (en) * | 2008-07-16 | 2009-03-25 | 中国科学院上海光学精密机械研究所 | Space phase shifter for synchronous phase-shifting interferometer |
CN103256991A (en) * | 2013-05-08 | 2013-08-21 | 中国科学院上海光学精密机械研究所 | Spatial phase shift lateral shearing interferometer |
CN204129323U (en) * | 2014-08-06 | 2015-01-28 | 张建平 | The total-reflection type prism assemblies of digital micro mirror projection light engine |
CN204909391U (en) * | 2015-07-24 | 2015-12-30 | 广东福地新视野光电技术有限公司 | OCT reference arm structure and OCT imaging system |
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