CN106490229A - Selenium-rich Ramulus et Folium Mussaendae Pubescentis - Google Patents
Selenium-rich Ramulus et Folium Mussaendae Pubescentis Download PDFInfo
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- CN106490229A CN106490229A CN201610990092.1A CN201610990092A CN106490229A CN 106490229 A CN106490229 A CN 106490229A CN 201610990092 A CN201610990092 A CN 201610990092A CN 106490229 A CN106490229 A CN 106490229A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/06—Treating tea before extraction; Preparations produced thereby
- A23F3/14—Tea preparations, e.g. using additives
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Abstract
The invention discloses a kind of Folium Camelliae sinensis, specifically selenium-rich Ramulus et Folium Mussaendae Pubescentis, spend 15 20 parts, 10 15 parts of Flos Chrysanthemi Indici, 58 parts of dragon well green tea, 35 parts of 46 part, mao pellet of Herba Anoectochili roxburghii, 24 parts of Fructus Pruni pseudocerasi, 23 parts of Cortex Phellodendri, 13 parts of Fructus Schisandrae Chinensis, 46 parts of Caulis et Folium Brassicae capitatae, 24 parts of Herba Apii graveolentis, 35 parts of blue berry dry powder, 35 parts of Fructus Artocarpi Heterophylli, 46 parts of leaf of Moringa, 35 parts of embryo nelumbinises, 13 parts of Cordyceps militaris (L.) Link., 24 parts of Radix Trichosanthis, 0.5 part of calcium gluconate, are quantitatively sprayed organic selenium solution in trophophase and then pluck 40 67 parts of obtained Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis including Herba Artemisiae montanae Artemisia.Selenium-rich Ramulus et Folium Mussaendae Pubescentis of the present invention, can allow the patient for drinking or eating the selenium-rich Ramulus et Folium Mussaendae Pubescentis, its cellular immunity to strengthen, and growth of cancer cells is suppressed.
Description
Technical field
The present invention relates to tea field, in particular to a kind of selenium-rich Ramulus et Folium Mussaendae Pubescentis.
Background technology
Ramulus et Folium Mussaendae Pubescentis are one of Chinese six big teas, and Ramulus et Folium Mussaendae Pubescentis have profile bud complete in the least, drape over one's shoulders milli all over the body, fragrant in the least fresh clearly, soup look Huang
Green limpid, light time sweet quality characteristic of flavour.Belong to slight fermented tea, be the special treasure in China's teas.Because of its finished product
Tea mostly is bud head, completely drapes over one's shoulders pekoe, and such as silver is gained the name like snow.
Selenium element is trace mineral nutrient needed by human, and the selenium total content of human body itself is about 6-20mg.Selenium time
The each histoorgan of cloth and body fluid, concentration highest in kidney are extremely important to enhance immunity and prophylaxis of cancer.
Also having in the related combine green tea, postfermented tea, black tea and selenium and realize tea rich in selenium (green tea, postfermented tea, black tea)
The precedent of preparation；But for the preparation of selenium-rich Ramulus et Folium Mussaendae Pubescentis but has no report, in view of the special drug effect performance of Ramulus et Folium Mussaendae Pubescentis, there is provided Yi Zhongfu
The preparation method of selenium Ramulus et Folium Mussaendae Pubescentis is people's technical problem urgently to be resolved hurrily.
For solving above-mentioned technical problem, Chinese patent CN104186737A discloses a kind of selenium-rich Ramulus et Folium Mussaendae Pubescentis and the selenium-rich is white
The preparation method of tea, the preparation method include：Before Folium Camelliae sinensis are plucked, the 18-22 days growth temperatures by Camellia sinensis are controlled in 25-35
DEG C, and per ten days to spraying organic selenium solution on tea shoot once；After withering naturally, Folium Camelliae sinensis are in the bar that relative humidity is 70-80%
Part bottom fermentation 3-4 hours, Folium Camelliae sinensis after being fermented；Will fermentation after Folium Camelliae sinensis relative humidity be 70-80%, temperature be 24-28 DEG C
Under conditions of dry to its water content be 6-10%, obtain selenium-rich Ramulus et Folium Mussaendae Pubescentis.
Above-mentioned patent obtains the Ramulus et Folium Mussaendae Pubescentis with selenium element by way of spraying organic selenium solution, but such Ramulus et Folium Mussaendae Pubescentis
Do not possess anticancer growth, strengthen the effect of patient's cellular immunity.
Content of the invention
The invention is intended to providing selenium-rich Ramulus et Folium Mussaendae Pubescentis, the patient for drinking or eating the selenium-rich Ramulus et Folium Mussaendae Pubescentis can be allowed, its cellular immunity
Strengthen, growth of cancer cells is suppressed.
In order to solve above-mentioned technical problem, this patent provides following technical scheme;
Selenium-rich Ramulus et Folium Mussaendae Pubescentis, including the raw material of following mass fraction, Herba Artemisiae montanae Artemisia flower 15-20 parts, Flos Chrysanthemi Indici 10-15 parts, dragon well green tea 5-8 parts,
Herba Anoectochili roxburghii 4-6 parts, hair pellet 3-5 parts, Fructus Pruni pseudocerasi 2-4 parts, Cortex Phellodendri 2-3 parts, Fructus Schisandrae Chinensis 1-3 parts, Caulis et Folium Brassicae capitatae 4-6 parts, Herba Apii graveolentis 2-4 parts,
Blue berry dry powder 3-5 part, Fructus Artocarpi Heterophylli 3-5 parts, leaf of Moringa 4-6 parts, embryo nelumbinises 3-5 parts, Cordyceps militaris (L.) Link. 1-3 parts, Radix Trichosanthis 2-4 parts,
0.5 part of calcium gluconate, organic selenium solution is quantitatively sprayed in trophophase and then plucked obtained Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis 40-67 parts.
With the Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis rich in selenium element as primary raw material in the present invention, other component contents are less, so subject
Claim still to run after fame with selenium-rich Ramulus et Folium Mussaendae Pubescentis.
Using technical scheme, its advantage is：The present invention is mainly by adjusting patient's immunocyte institute
The elements such as the chlorophyll that lacks, tea polyphenols, alkaloid, strength remove free radical, accelerate the generation of interior tumor cell death toxin
The effect of thanking, it is to avoid these injuries of death of neoplastic cells toxin to lymphocyte, and it is scorching to improve the aseptic of tumor microenvironment
Disease is reacted, and serves the effect for adjusting immunocyte balance.
Further, 57 parts of the Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis, Herba Artemisiae montanae Artemisia spend 17 parts, 13 parts of Flos Chrysanthemi Indici, 7 parts of dragon well green tea, Herba Anoectochili roxburghii 5 part, mao
Red 4 parts, 3 parts of Fructus Pruni pseudocerasi, 3 parts of Cortex Phellodendri, 2 parts of Fructus Schisandrae Chinensis, 5 parts of Caulis et Folium Brassicae capitatae, 4 parts of Herba Apii graveolentis, 3 parts of blue berry dry powder, 3 parts of Fructus Artocarpi Heterophylli, peppery
6 parts of wooden leaf, 5 parts of embryo nelumbinises, 2 parts of Cordyceps militaris (L.) Link., 2 parts of Radix Trichosanthis, 0.5 part of calcium gluconate.
Experiments verify that, after each component of the present invention is further constrained according to the above ratio, which is to cellular immunity
Potentiation further can increase.
Further, Folium Nelumbinis 12-14 parts are also included；
Folium Nelumbinis contain multiple alkaloids such as nuciferine, miltanthin and nuciferine and vitamin C, polysaccharide；Have heat-clearing and toxic substances removing, removing heat from blood,
The effect of hemostasis, is added in selenium-rich Ramulus et Folium Mussaendae Pubescentis, can strengthen the detoxicating functions of the present invention.
Further, also include 2 parts of Fructus Lycii；
Rich in lycium barbarum polysaccharide in Fructus Lycii, cytophagous phagocytic function can be significantly improved, improve the multiplication capacity of lymphocyte.
Further, the selenium-rich Ramulus et Folium Mussaendae Pubescentis are powder formulation.
Further, the selenium-rich Ramulus et Folium Mussaendae Pubescentis are decoction dosage form.
Decoction is little with the overall efficacy difference of powder, but the phase that takes effect of powder formulation is shorter, so for acute disease
Shape, preferably uses powder formulation.
Description of the drawings
Fig. 1 is pancreatic cancer cell MTT testing results（Amplification 4 × 10 × 10）；
Fig. 2 is stomach cancer cell MTT testing results（Amplification 4 × 10 × 10）.
Specific embodiment
Below by specific embodiment, the present invention is further detailed explanation：
Embodiment one
The present embodiment selenium-rich Ramulus et Folium Mussaendae Pubescentis, including the raw material of following mass fraction, 40 parts of Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis, Herba Artemisiae montanae Artemisia spend 20 parts, Flos Chrysanthemi Indici 13
Part, 8 parts of dragon well green tea, 3 parts of 6 part, mao pellet of Herba Anoectochili roxburghii, 4 parts of Fructus Pruni pseudocerasi, 2 parts of Cortex Phellodendri, 3 parts of Fructus Schisandrae Chinensis, 5 parts of Caulis et Folium Brassicae capitatae, 3 parts of Herba Apii graveolentis, indigo plant
4 parts of certain kind of berries dry powder, 5 parts of Fructus Artocarpi Heterophylli, 4 parts of leaf of Moringa, 3.5 parts of embryo nelumbinises, 1.5 parts of Cordyceps militaris (L.) Link., 4 parts of Radix Trichosanthis, calcium gluconate
0.5 part.
Embodiment two
The present embodiment selenium-rich Ramulus et Folium Mussaendae Pubescentis, including the raw material of following mass fraction, are quantitatively sprayed organic selenium solution then in trophophase
59 parts of Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis, Herba Artemisiae montanae Artemisia obtained in plucking spend 20 parts, 11 parts of Flos Chrysanthemi Indici, 5 parts of dragon well green tea, 3 parts of 6 part, mao pellet of Herba Anoectochili roxburghii, Fructus Pruni pseudocerasi
4 parts, 3 parts of Cortex Phellodendri, 3 parts of Fructus Schisandrae Chinensis, 4.5 parts of Caulis et Folium Brassicae capitatae, 3.5 parts of Herba Apii graveolentis, 4.5 parts of blue berry dry powder, 3 parts of Fructus Artocarpi Heterophylli, leaf of Moringa 4
Part, 3 parts of embryo nelumbinises, 3 parts of Cordyceps militaris (L.) Link., 4 parts of Radix Trichosanthis, 0.5 part of calcium gluconate.
Embodiment three
57 parts of the Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis, Herba Artemisiae montanae Artemisia spend 17 parts, 13 parts of Flos Chrysanthemi Indici, 7 parts of dragon well green tea, 4 parts of 5 part, mao pellet of Herba Anoectochili roxburghii, Fructus Pruni pseudocerasi 3
Part, 3 parts of Cortex Phellodendri, 2 parts of Fructus Schisandrae Chinensis, 5 parts of Caulis et Folium Brassicae capitatae, 4 parts of Herba Apii graveolentis, 3 parts of blue berry dry powder, 3 parts of Fructus Artocarpi Heterophylli, 6 parts of leaf of Moringa, Semen Nelumbinis
5 parts of core, 2 parts of Cordyceps militaris (L.) Link., 2 parts of Radix Trichosanthis, 0.5 part of calcium gluconate, 2 parts of Fructus Lycii, 12 parts of Folium Nelumbinis.
Example IV
The present embodiment selenium-rich Ramulus et Folium Mussaendae Pubescentis, including the raw material of following mass fraction, are quantitatively sprayed organic selenium solution then in trophophase
66 parts of Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis, Herba Artemisiae montanae Artemisia obtained in plucking spend 20 parts, 9 parts of Flos Chrysanthemi Indici, 4 parts of dragon well green tea, 8 parts of 3 part, mao pellet of Herba Anoectochili roxburghii, Fructus Pruni pseudocerasi 5
Part, 3 parts of Cortex Phellodendri, 4 parts of Caulis et Folium Brassicae capitatae, 3 parts of Herba Apii graveolentis, 3 parts of blue berry dry powder, 8 parts of Fructus Artocarpi Heterophylli, 7 parts of leaf of Moringa, 6 parts of embryo nelumbinises, pupa worm
Careless 4 parts, 5 parts of Radix Trichosanthis
Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis in aforementioned four embodiment be trophophase just quantitatively sprayed organic selenium solution then pluck prepared
, its concrete preparation method is included in before plucking Folium Camelliae sinensis and controls the growth temperature of Camellia sinensis at 25-35 DEG C in 18-22 days, and per ten
It is to spraying organic selenium solution once on tea shoot；After withering naturally, Folium Camelliae sinensis ferment under conditions of relative humidity is 70-80%
3-4 hours, Folium Camelliae sinensis after being fermented；Will fermentation after Folium Camelliae sinensis relative humidity be 70-80%, temperature be 24-28 DEG C under conditions of
It is 6-10% to dry to its water content, obtains Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis.
Powder is beaten to the corresponding component of four embodiments respectively now, (the powder gross mass of four embodiments is equal used as powder
For 100g), the cell of patient in the gruel of the daily consumption for being put into patient, is then extracted, makees following observation experiment, Fig. 1, a in 2
Represent that embodiment one, b represents that embodiment two, c represents that embodiment three, d represents example IV, so as to prove the present invention to cell
The potentiation of immunity.
Experiment one
If four experimental grouies, respectively correspondingly four apply example, set 6 repetitions per group, take Patients with Pancreatic Cancer logarithmic (log) phase growth
Insulinoma cells, are made into the cell that density is 5 × 104～2 × 105/mL with the RPMI RPMI-1640s containing 10%FBS and hang
Liquid, is inoculated in 96 well culture plates, per 100 μ L of hole, 37 DEG C, 5%CO2After incubator training 2h, then after cellar culture 24h, add per hole
Enter 20 μ L 5mg/mL MTT solution, continue culture 4h, terminate culture, discard supernatant in hole.150 μ L DMSO are added per hole, is shaken
Bed vibration 10min, is then observed with medical microscope, and observation result is as shown in Figure 1.
Experiment two
This experiment is that with the difference of experiment one this provides the stomach oncocyte of Patients with Gastric Cancer logarithmic (log) phase growth, other realities
Test step and parameter is identical, last observation result is as shown in Figure 2.
From Fig. 1,2, the medicine scope of embodiment 1-3 belongs in zone of reasonableness, for suppression and the cell of cancerous cell
Substantially, corresponding cancerous cell is effectively suppressed the increasing action of immunity.Especially embodiment three, examine in different cancerous cell
Have outstanding performance in survey, can be as the presently preferred embodiments.
Selenium-rich Ramulus et Folium Mussaendae Pubescentis of the present invention also have decoction dosage form in addition to powder formulation, wherein prepare the side of the selenium-rich Ramulus et Folium Mussaendae Pubescentis decoction
Method, comprises the steps：
（1）The Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis of above-mentioned mass fraction, Anoectochilus roxburghii, Cortex Phellodendri, Fructus Schisandrae Chinensis, leaf of Moringa, embryo nelumbinises, Cordyceps militaris (L.) Link. are cleaned mixed
Close, then water extraction 1-2 time, merge Aqueous extracts and be concentrated into 100-150ml, standby；
（2）Weigh by weight hair pellet, Fructus Pruni pseudocerasi, Caulis et Folium Brassicae capitatae, Herba Apii graveolentis clean smash to pieces, be subsequently adding blue berry dry powder, pollen and
Appropriate water, mixing beating are obtained mixed serum, standby；
（3）Weigh Herba Artemisiae montanae Artemisia flower, Flos Chrysanthemi Indici, dragon well green tea by weight, clean, drain after pulverize, then with above-mentioned steps（1）
Chinese traditional medicine water extract, step（2）Other residues such as mixed serum and nutrient extract make raw material mixing, and add appropriate water, boil
Boiling 30-40 minutes, then slow fire is stewed 40-50 minutes slowly again, you can the millet paste of the selenium-rich Ramulus et Folium Mussaendae Pubescentis is obtained.
The instructions of taking of powder is that corresponding component is beaten powder, as powder, in the gruel of the daily consumption for being put into patient
Edible, the instructions of taking of the decoction is also to eat in the gruel for put into daily consumption, for convenience Experimental comparison, with embodiment
As a example by one, it is desirable to the raw material gross mass in embodiment one（Water is not included）For 200g, then take 100g and make powder, 100g under remainder
Make decoction, take to two groups of Patients with Gastric Cancer respectively, every group of gastric cancer has 20 people, the wherein Patients with Gastric Cancer of powder group taking per capita
Second week just had more than half patients the phenomenon of appetite growth occur, and decoction group will just have more than half patients at the 3rd week
There is the phenomenon that appetite increases, it can be seen that the powder formulation quick result of the present invention.
Gastric cancer mouse group with chemotherapy（20 per group）With the selenium-rich Ramulus et Folium Mussaendae Pubescentis for drinking effective ingredient 100g daily（Embodiment three
Decoction）Experiment mouse group compare, observe 20 days, both organize average tumour inhibiting rate（（Before experiment after tumor quality-experiment 20 days
Tumor quality）Tumor quality before/experiment）：To 45.9%, the inhibitory rate of selenium-rich Ramulus et Folium Mussaendae Pubescentis group is arrived the tumor inhibitory rate of chemotherapy group
74 .3%.
Above-described is only embodiments of the invention, and in scheme, the known general knowledge here such as concrete structure and characteristic is not made
Excessive description.It should be pointed out that for a person skilled in the art, on the premise of without departing from present configuration, can be with
Some deformations and improvement is made, these should also be considered as protection scope of the present invention, these are implemented all without the impact present invention
Effect and practical applicability.This application claims protection domain should be defined by the content of its claim, in description
Specific embodiment etc. records the content that can be used for explaining claim.
Claims (6)
1. selenium-rich Ramulus et Folium Mussaendae Pubescentis, it is characterised in that：Including the raw material of following mass fraction, Herba Artemisiae montanae Artemisia flower 15-20 parts, Flos Chrysanthemi Indici 10-15 parts,
Dragon well green tea 5-8 parts, Herba Anoectochili roxburghii 4-6 parts, hair pellet 3-5 parts, Fructus Pruni pseudocerasi 2-4 parts, Cortex Phellodendri 2-3 parts, Fructus Schisandrae Chinensis 1-3 parts, Caulis et Folium Brassicae capitatae 4-6
Part, Herba Apii graveolentis 2-4 parts, blue berry dry powder 3-5 part, Fructus Artocarpi Heterophylli 3-5 parts, leaf of Moringa 4-6 parts, embryo nelumbinises 3-5 parts, Cordyceps militaris (L.) Link. 1-3 parts,
Radix Trichosanthis 2-4 parts, 0.5 part of calcium gluconate, organic selenium solution is quantitatively sprayed in trophophase and then plucked obtained Ramulus et Folium Mussaendae Pubescentis tea
Leaf 40-67 parts.
2. selenium-rich Ramulus et Folium Mussaendae Pubescentis according to claim 1, it is characterised in that：57 parts of the Ramulus et Folium Mussaendae Pubescentis Folium Camelliae sinensis, Herba Artemisiae montanae Artemisia spend 17 parts, Herba Dendranthematis indici
Spend 13 parts, 7 parts of dragon well green tea, 4 parts of 5 part, mao pellet of Herba Anoectochili roxburghii, 3 parts of Fructus Pruni pseudocerasi, 3 parts of Cortex Phellodendri, 2 parts of Fructus Schisandrae Chinensis, 5 parts of Caulis et Folium Brassicae capitatae, Herba Apii graveolentis 4
Part, 3 parts of blue berry dry powder, 3 parts of Fructus Artocarpi Heterophylli, 6 parts of leaf of Moringa, 5 parts of embryo nelumbinises, 2 parts of Cordyceps militaris (L.) Link., 2 parts of Radix Trichosanthis, calcium gluconate
0.5 part.
3. selenium-rich Ramulus et Folium Mussaendae Pubescentis according to claim 2, it is characterised in that：Also include Folium Nelumbinis 12-14 parts.
4. selenium-rich Ramulus et Folium Mussaendae Pubescentis according to claim 3, it is characterised in that：Also include 2 parts of Fructus Lycii.
5. selenium-rich Ramulus et Folium Mussaendae Pubescentis according to claim 3, it is characterised in that：The selenium-rich Ramulus et Folium Mussaendae Pubescentis are powder formulation.
6. selenium-rich Ramulus et Folium Mussaendae Pubescentis according to claim 3, it is characterised in that：The selenium-rich Ramulus et Folium Mussaendae Pubescentis are decoction dosage form.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107410574A (en) * | 2017-09-17 | 2017-12-01 | 胡爱琴 | A kind of clearing heat and detoxicating white tea |
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| CN103271185A (en) * | 2013-06-19 | 2013-09-04 | 山东华夏茶联茶业有限公司 | Health white tea |
| CN104186737A (en) * | 2014-09-25 | 2014-12-10 | 张丽珍 | Preparation method of selenium-rich white tea and selenium-rich white tea prepared with method |
| CN106070835A (en) * | 2016-06-07 | 2016-11-09 | 安徽国顺中药发展有限公司 | A kind of aid digestion Fructus Sapindi Mukouossi scented tea and preparation method thereof |
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2016
- 2016-11-10 CN CN201610990092.1A patent/CN106490229A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103271185A (en) * | 2013-06-19 | 2013-09-04 | 山东华夏茶联茶业有限公司 | Health white tea |
| CN104186737A (en) * | 2014-09-25 | 2014-12-10 | 张丽珍 | Preparation method of selenium-rich white tea and selenium-rich white tea prepared with method |
| CN106070835A (en) * | 2016-06-07 | 2016-11-09 | 安徽国顺中药发展有限公司 | A kind of aid digestion Fructus Sapindi Mukouossi scented tea and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107410574A (en) * | 2017-09-17 | 2017-12-01 | 胡爱琴 | A kind of clearing heat and detoxicating white tea |
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