CN106470684B - 涉及维生素d的组合物 - Google Patents

涉及维生素d的组合物 Download PDF

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Publication number
CN106470684B
CN106470684B CN201580034583.2A CN201580034583A CN106470684B CN 106470684 B CN106470684 B CN 106470684B CN 201580034583 A CN201580034583 A CN 201580034583A CN 106470684 B CN106470684 B CN 106470684B
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vitamin
compound
formula
antibody
analyte
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Chinese (zh)
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CN106470684A (zh
Inventor
滕铸
廖起牧
M.沙马
M.A.德里南
魏铁全
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Siemens Healthcare Diagnostics Inc
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Siemens Healthcare Diagnostics Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580034583.2A 2014-06-27 2015-06-22 涉及维生素d的组合物 Active CN106470684B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462018008P 2014-06-27 2014-06-27
US62/018008 2014-06-27
PCT/US2015/036904 WO2015200180A1 (en) 2014-06-27 2015-06-22 Compositions relating to vitamin d

Publications (2)

Publication Number Publication Date
CN106470684A CN106470684A (zh) 2017-03-01
CN106470684B true CN106470684B (zh) 2021-03-23

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CN201580034583.2A Active CN106470684B (zh) 2014-06-27 2015-06-22 涉及维生素d的组合物

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US (2) US10106498B2 (https=)
EP (1) EP3177297B1 (https=)
JP (1) JP6494670B2 (https=)
KR (1) KR102528381B1 (https=)
CN (1) CN106470684B (https=)
AU (1) AU2015280290B2 (https=)
BR (2) BR112016030507B1 (https=)
ES (1) ES2877562T3 (https=)
WO (1) WO2015200180A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015200182A1 (en) * 2014-06-27 2015-12-30 Siemens Healthcare Diagnostics Inc. Binding partners specific for vitamin d epimers
EP3234104B1 (en) 2014-12-17 2018-08-22 Siemens Healthcare Diagnostics Inc. Accurate assay measurement of hydrophobic haptenic analytes
CN107652302B (zh) * 2016-07-25 2020-09-15 深圳迈瑞生物医疗电子股份有限公司 化合物、缀合物、试剂盒及其用途
EP3590498A4 (en) 2017-03-03 2020-12-16 CTC Bio, Inc. PREPARATION, INCLUDING AN INCLUSION COMPLEX OF VARENICLINE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREFOR, FOR ORAL ADMINISTRATION
CN116143692B (zh) * 2019-02-01 2025-09-16 科美博阳诊断技术(上海)有限公司 用于测定维生素d的含量或存在的化合物、产品和方法
CN111474341B (zh) * 2020-04-28 2023-09-29 上海泰辉生物科技有限公司 基于免疫比浊和余辉发光的均相联合检测试剂和检测方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103857698A (zh) * 2011-05-20 2014-06-11 西门子医疗保健诊断公司 针对25-羟基维生素d2和d3的抗体及其用途

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JPH09143154A (ja) 1995-11-20 1997-06-03 Kureha Chem Ind Co Ltd ビタミンｄ３ 誘導体の製造方法
EP0873126A4 (en) 1995-12-29 2000-04-19 A And D Assay Inc BRANDED VITAMIN COMPOUNDS AND THEIR USE
US8133694B2 (en) 1998-06-25 2012-03-13 Immundiagnostik Ag Functional vitamin D derivatives and method of determining 25-hydroxy- and 1α, 25-dihydroxy vitamin D
AU763458B2 (en) * 1998-06-25 2003-07-24 Biomedica Gmbh Functional vitamin D derivatives and a method for determining 25-hydroxy-vitamin D and 1alpha,25-dihydroxy-vitamin D
US7253293B2 (en) 2004-01-06 2007-08-07 Andrzej Slominski Enzymatic method to produce 7-dehydropregnenolone, vitamin D3-like compounds and derivatives thereof
WO2006096555A1 (en) 2005-03-04 2006-09-14 Women And Infants Hospital Of Ri, Inc. Compositions and methods for cancer treatment
CN100431374C (zh) * 2005-06-28 2008-11-05 上海原动力通信科技有限公司 高速下行分组接入业务用户终端在多载波小区的工作方法
AU2013263349B2 (en) * 2012-05-17 2016-09-08 Extend Biosciences, Inc Carriers for improved drug delivery
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
WO2014085486A2 (en) 2012-11-30 2014-06-05 Waters Technologies Corporation Methods and apparatus for the analysis of vitamin d metabolites
US9618523B2 (en) 2013-02-28 2017-04-11 Siemens Healthcare Diagnostics Inc. Methods and reagents for determining isomeric analytes
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
CN106661114B (zh) * 2014-06-27 2019-01-29 西门子医疗保健诊断公司 维生素d测定法中对维生素d差向异构体特异性的结合配偶体
KR20180023047A (ko) 2014-06-27 2018-03-06 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 에피머에 대한 검정 방법
WO2015200182A1 (en) * 2014-06-27 2015-12-30 Siemens Healthcare Diagnostics Inc. Binding partners specific for vitamin d epimers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103857698A (zh) * 2011-05-20 2014-06-11 西门子医疗保健诊断公司 针对25-羟基维生素d2和d3的抗体及其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Analytical measurement and clinical relevance of vitamin D3 C3-epimer;Dana Bailey;《Clinical Biochemistry》;20121112;第46卷;190-196 *

Also Published As

Publication number Publication date
EP3177297A4 (en) 2017-11-29
US20190016677A1 (en) 2019-01-17
JP6494670B2 (ja) 2019-04-03
JP2017522298A (ja) 2017-08-10
EP3177297B1 (en) 2021-04-07
BR112016030507B1 (pt) 2023-03-28
AU2015280290B2 (en) 2019-09-19
BR112016030507A8 (pt) 2021-07-20
CN106470684A (zh) 2017-03-01
BR112016030507A2 (pt) 2017-08-22
BR122022025940B1 (pt) 2023-11-28
ES2877562T3 (es) 2021-11-17
US10399938B2 (en) 2019-09-03
AU2015280290A1 (en) 2016-12-01
EP3177297A1 (en) 2017-06-14
US10106498B2 (en) 2018-10-23
KR20170027791A (ko) 2017-03-10
US20170114012A1 (en) 2017-04-27
KR102528381B1 (ko) 2023-05-02
WO2015200180A1 (en) 2015-12-30

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