BR112016030507B1 - Compostos relacionados à vitamina d, e composição farmacêutica - Google Patents

Compostos relacionados à vitamina d, e composição farmacêutica Download PDF

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Publication number
BR112016030507B1
BR112016030507B1 BR112016030507-8A BR112016030507A BR112016030507B1 BR 112016030507 B1 BR112016030507 B1 BR 112016030507B1 BR 112016030507 A BR112016030507 A BR 112016030507A BR 112016030507 B1 BR112016030507 B1 BR 112016030507B1
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BR
Brazil
Prior art keywords
vitamin
compound
formula
antibody
analyte
Prior art date
Application number
BR112016030507-8A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112016030507A2 (pt
BR112016030507A8 (pt
Inventor
Zhu Teng
Qimu Liao
Manoj Sharma
Martin A. Drinan
Tie Quan Wei
Original Assignee
Siemens Healthcare Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics Inc filed Critical Siemens Healthcare Diagnostics Inc
Priority to BR122022025940-5A priority Critical patent/BR122022025940B1/pt
Publication of BR112016030507A2 publication Critical patent/BR112016030507A2/pt
Publication of BR112016030507A8 publication Critical patent/BR112016030507A8/pt
Publication of BR112016030507B1 publication Critical patent/BR112016030507B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112016030507-8A 2014-06-27 2015-06-22 Compostos relacionados à vitamina d, e composição farmacêutica BR112016030507B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122022025940-5A BR122022025940B1 (pt) 2014-06-27 2015-06-22 Kit para determinação da presença e/ou quantidade de analitos de vitamina d

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462018008P 2014-06-27 2014-06-27
US62/018,008 2014-06-27
PCT/US2015/036904 WO2015200180A1 (en) 2014-06-27 2015-06-22 Compositions relating to vitamin d

Publications (3)

Publication Number Publication Date
BR112016030507A2 BR112016030507A2 (pt) 2017-08-22
BR112016030507A8 BR112016030507A8 (pt) 2021-07-20
BR112016030507B1 true BR112016030507B1 (pt) 2023-03-28

Family

ID=54938699

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112016030507-8A BR112016030507B1 (pt) 2014-06-27 2015-06-22 Compostos relacionados à vitamina d, e composição farmacêutica
BR122022025940-5A BR122022025940B1 (pt) 2014-06-27 2015-06-22 Kit para determinação da presença e/ou quantidade de analitos de vitamina d

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122022025940-5A BR122022025940B1 (pt) 2014-06-27 2015-06-22 Kit para determinação da presença e/ou quantidade de analitos de vitamina d

Country Status (9)

Country Link
US (2) US10106498B2 (https=)
EP (1) EP3177297B1 (https=)
JP (1) JP6494670B2 (https=)
KR (1) KR102528381B1 (https=)
CN (1) CN106470684B (https=)
AU (1) AU2015280290B2 (https=)
BR (2) BR112016030507B1 (https=)
ES (1) ES2877562T3 (https=)
WO (1) WO2015200180A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106661115A (zh) * 2014-06-27 2017-05-10 西门子医疗保健诊断公司 对维生素d差向异构体特异性的结合配偶体
EP3234104B1 (en) 2014-12-17 2018-08-22 Siemens Healthcare Diagnostics Inc. Accurate assay measurement of hydrophobic haptenic analytes
CN107652302B (zh) * 2016-07-25 2020-09-15 深圳迈瑞生物医疗电子股份有限公司 化合物、缀合物、试剂盒及其用途
CN110381919A (zh) 2017-03-03 2019-10-25 西梯茜生命工学股份有限公司 含有伐尼克兰或其药学上可接受的盐的包合复合物的口服施用制剂
CN116143692B (zh) * 2019-02-01 2025-09-16 科美博阳诊断技术(上海)有限公司 用于测定维生素d的含量或存在的化合物、产品和方法
CN111474341B (zh) * 2020-04-28 2023-09-29 上海泰辉生物科技有限公司 基于免疫比浊和余辉发光的均相联合检测试剂和检测方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09143154A (ja) * 1995-11-20 1997-06-03 Kureha Chem Ind Co Ltd ビタミンｄ３ 誘導体の製造方法
DE873126T1 (de) * 1995-12-29 2000-11-02 A And D Assay, Inc. Markierte vitamin d-verbindungen und deren verwendung
US8133694B2 (en) 1998-06-25 2012-03-13 Immundiagnostik Ag Functional vitamin D derivatives and method of determining 25-hydroxy- and 1α, 25-dihydroxy vitamin D
WO1999067211A1 (de) * 1998-06-25 1999-12-29 Immundiagnostik Gesellschaft Für Produktion Und Vertrieb Von Labordiagnostika Mbh FUNKTIONELLE VITAMIN-D-DERIVATE UND VERFAHREN ZUR BESTIMMUNG VON 25-HYDROXY- UND 1α,25-DIHYDROXY-VITAMIN-D
US7253293B2 (en) * 2004-01-06 2007-08-07 Andrzej Slominski Enzymatic method to produce 7-dehydropregnenolone, vitamin D3-like compounds and derivatives thereof
US20100144671A1 (en) * 2005-03-04 2010-06-10 Women And Infants Hospital Of Ri, Inc. Compositions and Methods for Cancer Treatment
CN100431374C (zh) * 2005-06-28 2008-11-05 上海原动力通信科技有限公司 高速下行分组接入业务用户终端在多载波小区的工作方法
US8785603B2 (en) * 2011-05-20 2014-07-22 Siemens Healthcare Diagnostics Inc. Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof
CN108524919A (zh) 2012-05-17 2018-09-14 延伸生物科学股份有限公司 用于改进的药物递送的载体
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
WO2014085486A2 (en) 2012-11-30 2014-06-05 Waters Technologies Corporation Methods and apparatus for the analysis of vitamin d metabolites
US9618523B2 (en) 2013-02-28 2017-04-11 Siemens Healthcare Diagnostics Inc. Methods and reagents for determining isomeric analytes
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
US9804176B2 (en) * 2014-06-27 2017-10-31 Siemens Healthcare Diagnostics Inc. Assays for vitamin D epimers
CN106661115A (zh) * 2014-06-27 2017-05-10 西门子医疗保健诊断公司 对维生素d差向异构体特异性的结合配偶体
ES2853525T3 (es) * 2014-06-27 2021-09-16 Siemens Healthcare Diagnostics Inc Parejas de unión específicas para epímeros de vitamina D en ensayos de vitamina D

Also Published As

Publication number Publication date
CN106470684B (zh) 2021-03-23
US20190016677A1 (en) 2019-01-17
KR20170027791A (ko) 2017-03-10
EP3177297A4 (en) 2017-11-29
AU2015280290A1 (en) 2016-12-01
BR112016030507A2 (pt) 2017-08-22
US20170114012A1 (en) 2017-04-27
KR102528381B1 (ko) 2023-05-02
US10399938B2 (en) 2019-09-03
JP6494670B2 (ja) 2019-04-03
AU2015280290B2 (en) 2019-09-19
BR122022025940B1 (pt) 2023-11-28
JP2017522298A (ja) 2017-08-10
ES2877562T3 (es) 2021-11-17
BR112016030507A8 (pt) 2021-07-20
CN106470684A (zh) 2017-03-01
US10106498B2 (en) 2018-10-23
WO2015200180A1 (en) 2015-12-30
EP3177297B1 (en) 2021-04-07
EP3177297A1 (en) 2017-06-14

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