CN106470684B - 涉及维生素d的组合物 - Google Patents

涉及维生素d的组合物 Download PDF

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Publication number
CN106470684B
CN106470684B CN201580034583.2A CN201580034583A CN106470684B CN 106470684 B CN106470684 B CN 106470684B CN 201580034583 A CN201580034583 A CN 201580034583A CN 106470684 B CN106470684 B CN 106470684B
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vitamin
compound
formula
antibody
analyte
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Chinese (zh)
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CN106470684A (zh
Inventor
滕铸
廖起牧
M.沙马
M.A.德里南
魏铁全
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Siemens Healthcare Diagnostics Inc
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Siemens Healthcare Diagnostics Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201580034583.2A 2014-06-27 2015-06-22 涉及维生素d的组合物 Active CN106470684B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462018008P 2014-06-27 2014-06-27
US62/018008 2014-06-27
PCT/US2015/036904 WO2015200180A1 (en) 2014-06-27 2015-06-22 Compositions relating to vitamin d

Publications (2)

Publication Number Publication Date
CN106470684A CN106470684A (zh) 2017-03-01
CN106470684B true CN106470684B (zh) 2021-03-23

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CN201580034583.2A Active CN106470684B (zh) 2014-06-27 2015-06-22 涉及维生素d的组合物

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US (2) US10106498B2 (enExample)
EP (1) EP3177297B1 (enExample)
JP (1) JP6494670B2 (enExample)
KR (1) KR102528381B1 (enExample)
CN (1) CN106470684B (enExample)
AU (1) AU2015280290B2 (enExample)
BR (2) BR122022025940B1 (enExample)
ES (1) ES2877562T3 (enExample)
WO (1) WO2015200180A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102309377B1 (ko) * 2014-06-27 2021-10-05 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 에피머에 특이적인 결합 파트너
JP6574839B2 (ja) 2014-12-17 2019-09-11 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． 疎水性ハプテン被検体の正確なアッセイ測定
CN107652302B (zh) * 2016-07-25 2020-09-15 深圳迈瑞生物医疗电子股份有限公司 化合物、缀合物、试剂盒及其用途
US11266658B2 (en) 2017-03-03 2022-03-08 Ctc Bio, Inc. Preparation, comprising inclusion complex of varenicline or pharmaceutically acceptable salt thereof, for oral administration
CN116143692B (zh) * 2019-02-01 2025-09-16 科美博阳诊断技术(上海)有限公司 用于测定维生素d的含量或存在的化合物、产品和方法
CN111474341B (zh) * 2020-04-28 2023-09-29 上海泰辉生物科技有限公司 基于免疫比浊和余辉发光的均相联合检测试剂和检测方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103857698A (zh) * 2011-05-20 2014-06-11 西门子医疗保健诊断公司 针对25-羟基维生素d2和d3的抗体及其用途

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JPH09143154A (ja) * 1995-11-20 1997-06-03 Kureha Chem Ind Co Ltd ビタミンｄ３ 誘導体の製造方法
JP2000503641A (ja) 1995-12-29 2000-03-28 エイ・アンド・ディ・アッセイ・インコーポレイテッド 標識ビタミンｄ化合物およびその使用
AU763458B2 (en) 1998-06-25 2003-07-24 Biomedica Gmbh Functional vitamin D derivatives and a method for determining 25-hydroxy-vitamin D and 1alpha,25-dihydroxy-vitamin D
US8133694B2 (en) 1998-06-25 2012-03-13 Immundiagnostik Ag Functional vitamin D derivatives and method of determining 25-hydroxy- and 1α, 25-dihydroxy vitamin D
US7253293B2 (en) * 2004-01-06 2007-08-07 Andrzej Slominski Enzymatic method to produce 7-dehydropregnenolone, vitamin D3-like compounds and derivatives thereof
WO2006096555A1 (en) 2005-03-04 2006-09-14 Women And Infants Hospital Of Ri, Inc. Compositions and methods for cancer treatment
CN100431374C (zh) 2005-06-28 2008-11-05 上海原动力通信科技有限公司 高速下行分组接入业务用户终端在多载波小区的工作方法
MX349035B (es) 2012-05-17 2017-07-07 Extend Biosciences Inc Portadores para el suministro mejorado de farmaco.
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9719970B2 (en) 2012-11-30 2017-08-01 Waters Technologies Corporation Methods and apparatus for the analysis of vitamin D metabolites
US9618523B2 (en) 2013-02-28 2017-04-11 Siemens Healthcare Diagnostics Inc. Methods and reagents for determining isomeric analytes
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
KR102309377B1 (ko) * 2014-06-27 2021-10-05 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 에피머에 특이적인 결합 파트너
KR20180021934A (ko) * 2014-06-27 2018-03-05 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 검정에서 비타민 d 에피머에 특이적인 결합 파트너
AU2015280288B2 (en) 2014-06-27 2019-07-11 Siemens Healthcare Diagnostics Inc. Assays for vitamin D epimers

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN103857698A (zh) * 2011-05-20 2014-06-11 西门子医疗保健诊断公司 针对25-羟基维生素d2和d3的抗体及其用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Analytical measurement and clinical relevance of vitamin D3 C3-epimer;Dana Bailey;《Clinical Biochemistry》;20121112;第46卷;190-196 *

Also Published As

Publication number Publication date
ES2877562T3 (es) 2021-11-17
KR102528381B1 (ko) 2023-05-02
WO2015200180A1 (en) 2015-12-30
EP3177297A1 (en) 2017-06-14
AU2015280290A1 (en) 2016-12-01
AU2015280290B2 (en) 2019-09-19
JP2017522298A (ja) 2017-08-10
JP6494670B2 (ja) 2019-04-03
US10106498B2 (en) 2018-10-23
US20190016677A1 (en) 2019-01-17
BR112016030507B1 (pt) 2023-03-28
US10399938B2 (en) 2019-09-03
US20170114012A1 (en) 2017-04-27
CN106470684A (zh) 2017-03-01
BR112016030507A8 (pt) 2021-07-20
BR112016030507A2 (pt) 2017-08-22
EP3177297A4 (en) 2017-11-29
EP3177297B1 (en) 2021-04-07
KR20170027791A (ko) 2017-03-10
BR122022025940B1 (pt) 2023-11-28

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