CN106420579A - Dendrobium huoshanense containing skin regeneration-promoting combined skin-care cream - Google Patents
Dendrobium huoshanense containing skin regeneration-promoting combined skin-care cream Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/892—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a hydroxy group, e.g. dimethiconol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Abstract
The invention discloses a dendrobium huoshanense containing skin regeneration-promoting combined skin-care cream. The dendrobium huoshanense containing skin regeneration-promoting combined skin-care cream is prepared from the following raw materials in parts by weight: 15-25 parts of a dendrobium huoshanense extract, 10-20 parts of a spiral snail secretion, 3-6 parts of squalane oil, 5-10 parts of a centella extract, 3-5 parts of a perilla extract, 3-6 parts of fermented water lily, 10-15 parts of placentin, 3-7 parts of salmon ovarian peptide, 5-10 parts of a parsley seed extract, 2-3 parts of a grape seed extract, 0.05-0.1 part of hyaluronic acid, 1.5-2.5 parts of water-soluble chitosan, 3-4 parts of an epidermal cell growth factor, 5-10 parts of ginseng and 5-10 parts of astragalus membranaceus. The prepared dendrobium huoshanense containing skin regeneration-promoting combined skin-care cream has significant functions of promoting cell regeneration and repairing and rebuilding tissues, and thus has relatively good moisturizing, anti-aging and repairing functions.
Description
Technical field
The present invention relates to skin care field, and in particular to a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream.
Background technology
Sensitive skin has following characteristics mostly;
1st, epiderm skin is thin, and blood capillary is obvious;
2nd, skin lacks gloss, cheek easily congested redness;
3rd, skin is caused easily to assume unsure state because of seasonal variations;Situation, it may appear that itch, play erythra;
4th, cold wind, food, water quality, ultraviolet, synthetic fibers, fragrance are easily received;Or the impact of material.The life of healthy skin
The reason cycle is 28 days, forms the compact texture of marshalling from basal layer to horny layer, provides skin sufficiently protection and moisturizing
Function.Skin has normal physiological period, and the horny layer horn cell of the skin the superiors can be arranged very neatly, and lines is extremely thin
Cause, oil-water balance.The skin metabolism period staggering of sensitive skin, epidermal structure arrangement is mixed and disorderly, Skin Cell also immaturity, natural
When Moisture factor and intercellular lipid are also manufactured without complete, horny layer is just peeled off, and keratodermatitis cell arrangement is irregular, and
And up can roll up crowded, the moisture content inside skin is easily lost in, the protection without sebum film, and excitor substance or allergin are easily invaded
Enter, cause the internal inflammation of skin.
At present, the product that most of antiallergic senses are repaired on the market, antiinflammatory of only calming, this has side to immediate allergic skin
Help, but use be little in fact to the conditioning of sensitive skin, and also cannot be truly the reparative regeneration for realizing skin.
Herba Dendrobii, also known as rice dry measure used in former times, is the superfine product in Herba Dendrobii, is the endangered rare medical material of China national.Which dries
Stem (Huo Fengdou) and fresh dry measure used in former times can all be used as medicine.
《Compendium of Materia Medica》Record:Herba Dendrobii is sweet flat nontoxic.Damaging the spleen and stomach, the eliminating impediment therapeutic method to keep the adverse QI flowing downwards is cured mainly, tonifying five ZANG-organses asthenia wins thin, reinforcing YIN-essence benefit
Essence, long term usage thickness the intestines and stomach, never sufficient in benefit, flat stomach gas, long muscle, by skin pathogenic heat miliaria gas, it is weak that foot knee joint aches cold numbness.Sedate is removed shies,
Make light of one's life by commiting suicide macrobiosis, QI invigorating heat extraction, man's waist foot weakness is controlled, is good for sun.By skin migratory arthralgia, cold long in bone, the kidney invigorating benefit power, strengthening bone and muscle, warms up
Water is dirty, Fructus Alpiniae Oxyphyllae clearing heat in QI system, controls heating spontaneous perspiration, plug in carbuncle evacuation of pus.
Dry measure used in former times is rich in polysaccharide, aminoacid and more than the ten kind of alkaloid such as dendrobine, Herba Dendrobii amine base suddenly.Through Chinese Academy of Medical Sciences's medicine
Identified with Institute of Zoology:Polyoses content is 18.974%, and total alkaloid content is 0.030%.Immunity of organism can be effectively improved
Function, to human body eye, pharynx, lung.The disease such as the organs such as stomach, intestinal, kidney and blood, cardiovascular has special efficacy.Energy anti-cataract, prolongs
Slow aging, mutation, antitumor.
Content of the invention
For solving the above problems, the invention provides a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream, can promote
The new life of cell and reconstruction tissue.
For achieving the above object, the technical scheme that the present invention takes is:
A kind of Herba Dendrobii promotes skin regeneration combination protective skin cream, is prepared from by the raw material of following weight portion:
Herba Dendrobii extract 15-25 part, spiral Limax juice 10-20 part, shark alkane oil 3-6 part, Herba Centellae extract
5-10 part, Folium perillae extract 3-5 part, water Flos Nelumbinis fermented product 3-6 part, Placenta extract 10-15 part, salmon ovary peptide 3-7 part, caraway seed
Extract 5-10 part, Semen Vitis viniferae extract 2-3 part, hyaluronic acid 0.05-0.1 part, water-soluble chitosan 1.5-2.5 part, epidermis
Cell growth factor 3-4 part, Radix Ginseng 5-10 part, Radix Astragali 5-10 part.
Preferably, the water Flos Nelumbinis yeast powder prepares gained by following steps:
Take the water Flos Nelumbinis that cleans after draining to be placed in steam-explosion jar, it is 0.7- to be first passed through nitrogen to steam explosion pressure inside the tank
1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.8-2.8min, according to the ratio microbe inoculation leaven of inoculum concentration 1.5-1.7%, keeping temperature 25-35 DEG C, fermentation
After 48-54 hour, high temperature sterilize, lyophilization, obtain water Flos Nelumbinis yeast powder.
Preferably, the microbe leaven is by lactobacilluss, Bacillus licheniformis, Corynebacterium glutamicum in mass ratio 3:
2:1 mixing gained.
Preferably, the Herba Dendrobii extract prepares gained by following steps:
S1, the Herba Dendrobii that drains will be cleaned be placed in steam-explosion jar, be first passed through nitrogen to steam explosion pressure inside the tank be
1.4MPa, explosion treatment 8-25min;Then it is 1.4-1.8MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.5-2.5min, room temperature is concentrated into relative density 1.10-1.20, is spray-dried concentrated solution, obtains powder body;
S2, in powder body add 3-8 times of water, by mass percentage be 0.5-2% ratio add neutral protease, 30-
0.5-2h is digested at 50 DEG C, filter, obtain enzymolysis solution;
S3, by naturally to thaw again after the fermentation liquid quick freeze of gained, make age of starch precipitation in extract;Collect supernatant
Liquid, remainder is centrifuged, and collects centrifugal liquid and is incorporated in supernatant;
S4, by supernatant with the flow velocity of 3-7BV/h pass through macroporous resin column, after dynamic adsorption saturation, given birth to epidermis cell
The long factor is colourless to effluent with the above-mentioned macroporous resin column of the flow velocity drip washing of 5-8BV/h, then is 50%-70%'s with volume fraction
Organic solvent carries out eluting with the flow velocity of 8-12BV/h, collects eluent, and concentrating under reduced pressure obtains extractum;
S5, will after extractum water dissolution with the flow velocity of 3-5BV/h pass through polyamide column, after dynamic adsorption saturation, use 3-7BV
Epithelical cell growth factor is with the above-mentioned polyamide column of the flow velocity drip washing of 2-10BV/h, then is having for 30%-50% with volume fraction
Machine solvent aqueous solution carries out eluting with the flow velocity of 5-10BV/h, and collecting has eluent, is spray-dried, obtains Herba Dendrobii extract.
Preferably, the Folium perillae extract prepares gained by following steps:
90% methanol or the ethanol solution of 6 times of volumes being added after fresh Folium Perillae micronizing, processes 1-3 minute, Gu
After liquid is separated, methanol or ethanol solution is reclaimed, concentrate so that extract is in paste, then with water-saturated n-butanol to extract
Extraction 3 times, after recycling design, drying concentrated in vacuo for extract obtains Folium perillae extract.
Preferably, the Apium graveolenss seed extract prepares gained by following steps:
Caraway seed is cleaned and is placed in steam-explosion jar after draining, it is 0.6-1.4MPa to be first passed through nitrogen to steam explosion pressure inside the tank,
Explosion treatment 8-25min;Then it is 1.4-1.8MPa, Steam explosion treatment 0.5-
After 2.5min, room temperature is down to, 90% ethanol solution of 6-10 times of volume is added, 1-3 minute is processed, after solid-liquid separation, reclaim second
Alcoholic solution, concentrates so that extract is in paste, then with water-saturated n-butanol, extract is extracted 3 times, after recycling design, will
Extract drying concentrated in vacuo, obtains Apium graveolenss seed extract.
The invention has the advantages that:
By the secretion of spiral Limax, Placenta extract and salmon ovary peptide and homemade Herba Dendrobii extract, Folium perillae extract
Synergism with Apium graveolenss seed extract so that the protective skin cream of gained has the significant new life for promoting cell and reconstruction group
The function of knitting;The reasonable interpolation of collaboration shark alkane oil, hyaluronic acid etc. so as to preferable moisturizing, anti-ageing and repair function.
Specific embodiment
In order that objects and advantages of the present invention become more apparent, with reference to embodiments the present invention is carried out further
Describe in detail.It should be appreciated that specific embodiment described herein is not used to limit this only in order to explain the present invention
Bright.
In following examples, the water Flos Nelumbinis yeast powder for being used prepares gained by following steps:
Take the water Flos Nelumbinis that cleans after draining to be placed in steam-explosion jar, it is 0.7- to be first passed through nitrogen to steam explosion pressure inside the tank
1.5MPa, explosion treatment 7-23min;Then it is 1.5-2.1MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.8-2.8min, according to the ratio microbe inoculation leaven of inoculum concentration 1.5-1.7%, keeping temperature 25-35 DEG C, fermentation
After 48-54 hour, high temperature sterilize, lyophilization, obtain water Flos Nelumbinis yeast powder, wherein, the microbe leaven by lactobacilluss,
Bacillus licheniformis, Corynebacterium glutamicum in mass ratio 3:2:1 mixing gained.
The Herba Dendrobii extract for being used prepares gained by following steps:
S1, the Herba Dendrobii that drains will be cleaned be placed in steam-explosion jar, be first passed through nitrogen to steam explosion pressure inside the tank be
1.4MPa, explosion treatment 8-25min;Then it is 1.4-1.8MPa to be passed through rapidly steam to steam explosion pressure inside the tank, at steam explosion
After reason 0.5-2.5min, room temperature is concentrated into relative density 1.10-1.20, is spray-dried concentrated solution, obtains powder body;
S2, in powder body add 3-8 times of water, by mass percentage be 0.5-2% ratio add neutral protease, 30-
0.5-2h is digested at 50 DEG C, filter, obtain enzymolysis solution;
S3, by naturally to thaw again after the fermentation liquid quick freeze of gained, make age of starch precipitation in extract;Collect supernatant
Liquid, remainder is centrifuged, and collects centrifugal liquid and is incorporated in supernatant;
S4, by supernatant with the flow velocity of 3-7BV/h pass through macroporous resin column, after dynamic adsorption saturation, given birth to epidermis cell
The long factor is colourless to effluent with the above-mentioned macroporous resin column of the flow velocity drip washing of 5-8BV/h, then is 50%-70%'s with volume fraction
Organic solvent carries out eluting with the flow velocity of 8-12BV/h, collects eluent, and concentrating under reduced pressure obtains extractum;
S5, will after extractum water dissolution with the flow velocity of 3-5BV/h pass through polyamide column, after dynamic adsorption saturation, use 3-7BV
Epithelical cell growth factor is with the above-mentioned polyamide column of the flow velocity drip washing of 2-10BV/h, then is having for 30%-50% with volume fraction
Machine solvent aqueous solution carries out eluting with the flow velocity of 5-10BV/h, and collecting has eluent, is spray-dried, obtains Herba Dendrobii extract.
The Folium perillae extract for being used prepares gained by following steps:
90% methanol or the ethanol solution of 6 times of volumes being added after fresh Folium Perillae micronizing, processes 1-3 minute, Gu
After liquid is separated, methanol or ethanol solution is reclaimed, concentrate so that extract is in paste, then with water-saturated n-butanol to extract
Extraction 3 times, after recycling design, drying concentrated in vacuo for extract obtains Folium perillae extract.
The Apium graveolenss seed extract for being used prepares gained by following steps:
Caraway seed is cleaned and is placed in steam-explosion jar after draining, it is 0.6-1.4MPa to be first passed through nitrogen to steam explosion pressure inside the tank,
Explosion treatment 8-25min;Then it is 1.4-1.8MPa, Steam explosion treatment 0.5-
After 2.5min, room temperature is down to, 90% ethanol solution of 6-10 times of volume is added, 1-3 minute is processed, after solid-liquid separation, reclaim second
Alcoholic solution, concentrates so that extract is in paste, then with water-saturated n-butanol, extract is extracted 3 times, after recycling design, will
Extract drying concentrated in vacuo, obtains Apium graveolenss seed extract.
The organic solvent for being used is the turpentine derivatives of natural origin, and the turpentine derivatives are different for pinene
Structure, disproportionation products.
Other materials is commercially available.
Embodiment 1
A kind of Herba Dendrobii promotes skin regeneration combination protective skin cream, is prepared from by the raw material of following weight portion:
15 parts of Herba Dendrobii extract, 10 parts of spiral Limax juice, 3 parts of shark alkane oil, 5 parts of Herba Centellae extract, Folium Perillae
3 parts of extract, 3 parts of water Flos Nelumbinis fermented product, 10 parts of Placenta extract, 3 parts of salmon ovary peptide, 5 parts of Apium graveolenss seed extract, Semen Vitis viniferae are extracted
2 parts of thing, 0.05 part of hyaluronic acid, 1.5 parts of water-soluble chitosan, 3 parts of epithelical cell growth factor, 5 parts of Radix Ginseng, 5 parts of the Radix Astragali.
Embodiment 2
A kind of Herba Dendrobii promotes skin regeneration combination protective skin cream, is prepared from by the raw material of following weight portion:
25 parts of Herba Dendrobii extract, 20 parts of spiral Limax juice, 6 parts of shark alkane oil, 10 parts of Herba Centellae extract, Folium Perillae
5 parts of extract, 6 parts of water Flos Nelumbinis fermented product, 15 parts of Placenta extract, 7 parts of salmon ovary peptide, 10 parts of Apium graveolenss seed extract, Semen Vitis viniferae are carried
Take 3 parts of thing, 0.1 part of hyaluronic acid, 2.5 parts of water-soluble chitosan, 4 parts of epithelical cell growth factor, 10 parts of Radix Ginseng, the Radix Astragali 10
Part.
Embodiment 3
A kind of Herba Dendrobii promotes skin regeneration combination protective skin cream, is prepared from by the raw material of following weight portion:
20 parts of Herba Dendrobii extract, 15 parts of spiral Limax juice, shark alkane oil 4.5 parts, 7.5 parts of Herba Centellae extract,
4 parts of Folium perillae extract, 4.5 parts of water Flos Nelumbinis fermented product, 12.5 parts of Placenta extract, 5 parts of salmon ovary peptide, 7.5 parts of Apium graveolenss seed extract,
2.5 parts of Semen Vitis viniferae extract, 0.075 part of hyaluronic acid, 2 parts of water-soluble chitosan, 3.5 parts of epithelical cell growth factor, Radix Ginseng
7.5 parts, 7.5 parts of the Radix Astragali.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (6)
1. a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream, it is characterised in that by the raw material preparation of following weight portion
Become:
Herba Dendrobii extract 15-25 part, spiral Limax juice 10-20 part, shark alkane oil 3-6 part, Herba Centellae extract 5-10
Part, Folium perillae extract 3-5 part, water Flos Nelumbinis fermented product 3-6 part, Placenta extract 10-15 part, salmon ovary peptide 3-7 part, caraway seed are extracted
Thing 5-10 part, Semen Vitis viniferae extract 2-3 part, hyaluronic acid 0.05-0.1 part, water-soluble chitosan 1.5-2.5 part, epidermis cell
Somatomedin 3-4 part, Radix Ginseng 5-10 part, Radix Astragali 5-10 part.
2. a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream as claimed in claim 1, it is characterised in that the water lotus
Flower yeast powder prepares gained by following steps:
Take the water Flos Nelumbinis that cleans after draining to be placed in steam-explosion jar, it is 0.7-1.5MPa, quick-fried to be first passed through nitrogen to steam explosion pressure inside the tank
Tear manages 7-23min;Then it is 1.5-2.1MPa, Steam explosion treatment 0.8-
After 2.8min, according to the ratio microbe inoculation leaven of inoculum concentration 1.5-1.7%, keeping temperature 25-35 DEG C, ferment 48-54
After hour, high temperature sterilize, lyophilization, obtain water Flos Nelumbinis yeast powder.
3. a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream as claimed in claim 1, it is characterised in that micro- life
Thing leaven is by lactobacilluss, Bacillus licheniformis, Corynebacterium glutamicum in mass ratio 3:2:1 mixing gained.
4. a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream as claimed in claim 1, it is characterised in that the Huoshan
Herba Dendrobii extract prepares gained by following steps:
S1, the Herba Dendrobii that drains will be cleaned be placed in steam-explosion jar, be first passed through nitrogen to steam explosion pressure inside the tank be 0.6-1.4MPa,
Explosion treatment 8-25min;Then it is 1.4-1.8MPa, Steam explosion treatment 0.5-
After 2.5min, room temperature is concentrated into relative density 1.10-1.20, is spray-dried concentrated solution, obtains powder body;
S2, in powder body add 3-8 times of water, by mass percentage be 0.5-2% ratio add neutral protease, 30-50 DEG C
Lower enzymolysis 0.5-2h, filters, obtains enzymolysis solution;
S3, by naturally to thaw again after the fermentation liquid quick freeze of gained, make age of starch precipitation in extract;Collect supernatant,
Remainder is centrifuged, and collects centrifugal liquid and is incorporated in supernatant;
S4, by supernatant with the flow velocity of 3-7BV/h pass through macroporous resin column, after dynamic adsorption saturation, use epidermal growth because
Son is colourless to effluent with the above-mentioned macroporous resin column of the flow velocity drip washing of 5-8BV/h, then is the organic of 50%-70% with volume fraction
Solvent carries out eluting with the flow velocity of 8-12BV/h, collects eluent, and concentrating under reduced pressure obtains extractum;
S5, will after extractum water dissolution with the flow velocity of 3-5BV/h pass through polyamide column, after dynamic adsorption saturation, use 3-7BV epidermis
Cell growth factor is with the above-mentioned polyamide column of the flow velocity drip washing of 2-10BV/h, then is the organic molten of 30%-50% with volume fraction
Agent aqueous solution carries out eluting with the flow velocity of 5-10BV/h, and collecting has eluent, is spray-dried, obtains Herba Dendrobii extract.
5. a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream as claimed in claim 1, it is characterised in that the Folium Perillae
Extract prepares gained by following steps:
90% methanol or the ethanol solution of 6 times of volumes being added after fresh Folium Perillae micronizing, processing 1-3 minute, solid-liquid divides
From rear, methanol or ethanol solution is reclaimed, concentrate so that extract is in paste, then 3 is extracted with water-saturated n-butanol to extract
Secondary, after recycling design, drying concentrated in vacuo for extract obtains Folium perillae extract.
6. a kind of Herba Dendrobii promotes skin regeneration combination protective skin cream as claimed in claim 1, it is characterised in that the Apium graveolenss
Seed extract prepares gained by following steps:
Caraway seed is cleaned and is placed in steam-explosion jar after draining, it is 0.6-1.4MPa, explosion to be first passed through nitrogen to steam explosion pressure inside the tank
Process 8-25min;Then it is 1.4-1.8MPa, Steam explosion treatment 0.5-2.5min
Afterwards, room temperature is down to, 90% ethanol solution of 6-10 times of volume is added, 1-3 minute is processed, after solid-liquid separation, ethanol solution is reclaimed,
Concentrate so that extract is in paste, then with water-saturated n-butanol, extract is extracted 3 times, after recycling design, extract is true
Empty concentrate drying, obtains Apium graveolenss seed extract.
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Cited By (4)
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CN107007700A (en) * | 2017-04-28 | 2017-08-04 | 珠海安生凤凰制药有限公司 | A kind of Chinese medicine composition promoting blood circulation and removing blood stasis and preparation method thereof |
CN108686084A (en) * | 2018-08-13 | 2018-10-23 | 临沂大学 | A kind of oral administration solid self-emulsifying dispersion for treating livestock and birds respiratory disease |
CN108938499A (en) * | 2018-09-26 | 2018-12-07 | 梅淑婕 | It is a kind of enhance elasticity of skin skin care compositions and facial mask preparation method |
US11786451B2 (en) | 2019-06-28 | 2023-10-17 | The Procter & Gamble Company | Skin care composition |
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