CN106420347B - A kind of method and intelligent medicine box system for improving patient's drug compliance - Google Patents

Abstract

The present invention relates to a method for improving patients' medication compliance and an intelligent medicine box system, which includes: setting up an intelligent medicine box system, which includes an intelligent medicine box device, a cloud platform and a mobile phone APP, and the intelligent medicine box device includes a central processing module, real-time Clock module, camera module, wireless communication module, MP3 player module, sensor module, storage module and speaker; establish a knowledge base, arrange the content in the knowledge base at different time points in the course of treatment, and form a stepped health education knowledge base ;Record the knowledge content in the knowledge base into a voice file, and then translate the file into different language versions, and store it in a classified and hierarchical manner; copy the voice file together with the directory to the memory card of the smart medicine box device, and the central processing unit Calculate the time of taking the medicine at any time, retrieve the voice file with the same name as the number of times or the number of days in the corresponding directory in the knowledge base on the memory card, and play or prompt to listen to realize the synchronous health education of the patient during the medicine taking process.

Description

A method for improving patient medication compliance and an intelligent medicine box system

technical field

The invention relates to the field of medicine, in particular to a method for improving patients' medication compliance and an intelligent medicine box system.

Background technique

At present, the rehabilitation treatment of many diseases is completed by taking long-term medication and chemotherapy, which requires patients to have a high degree of medication compliance throughout the course of treatment, otherwise not only will they not recover, but even cause many other adverse consequences. For this reason, many medical institutions and scientific research institutes at home and abroad are conducting research on medication compliance. The research results show that the factors that affect patients' medication compliance mainly include the following aspects: patients feel better and stop taking drugs, side effects lead to drug withdrawal or even Resistance to medication, weak health awareness of patients leads to irregular medication behavior, lack of recovery beliefs of patients giving up medication, tense doctor-patient relationship and patients' distrust of doctor's orders, lack of medical service resources resulting in insufficient follow-up and follow-up, patients are easy to forget, etc.

In the existing technology, most of the products that improve patients’ medication compliance only focus on the factor of “patient forgetting” to solve problems such as missed doses and wrong doses caused by patients’ memory errors. Most of the product function designs use alarm bells to remind patients Taking medicine, the sensor recognizes the patient's action of taking medicine, and then judges whether the medicine is taken according to whether the action of taking medicine occurs, and finally realizes the supervision of missed dose by sending a notification message to the guardian. E.g:

The application number is 201310701504.1, and the application date is 2013.12.18, which discloses a smart medicine box, including a control circuit, a medicine cartridge holder and at least one medicine cartridge; the medicine cartridge is placed in the medicine cartridge holder, through The bottom of the cartridge is against the medication monitoring circuit of the control circuit, so that the medication monitoring circuit is in an open state; when the cartridge is picked up, the medication monitoring circuit is turned on; the medication monitoring circuit includes The main body of the monitoring circuit and the circuit breaker connector, and the main body of the monitoring circuit is a circuit breaker structure, one end of the circuit breaker connector is connected to one end of the circuit breaker structure, and the other end is connected to the other end of the circuit breaker structure after the cartridge is picked up. The open circuit and conduction of the medication monitoring circuit are realized, and then the control circuit can realize a series of actions such as judging whether the patient has taken the medicine in the corresponding cartridge, canceling the interval voice alarm, canceling the interval light alarm, recording the medication event, changing the light prompt, etc. .

The application number is 201310272970.2, and the application date is 2013.07.02, which discloses an intelligent medicine box system, which includes a medicine box body and a box cover. The medicine box body is divided into two parts: a medicine storage room and a control room. Part; wherein there is at least one medicine storehouse in the medicine storage room, the bottom of the medicine storehouse is a semi-inverted cone-shaped detection device arranged in the medicine storage room, which is used to detect the condition of the medicine in the medicine box body, and a light-emitting device is arranged at the bottom of the medicine storehouse device. In the control room, there are controllers, control buttons, sounding devices, vibration devices and position balance sensors. The controller is integrated with a central control chip, which realizes the connection between the medicine box and the smart terminal through wireless data transmission. The invention enables the user to know the state of the medicine in the medicine box effectively, and can easily set the time for taking the medicine, and can accurately and effectively remind the user. At the same time, it is convenient to record the status of medication and replenish new medicines in real time, and the binding function can be used to reduce the problem of users forgetting to carry emergency medicine boxes.

The application number is 201210176315.2, and the invention with the application date of 2012.05.31 discloses a smart medicine box, including a PC, a repeater, and multiple smart medicine boxes; the PC and the repeater are connected by a network cable, and the The repeater communicates with multiple smart medicine boxes wirelessly. The intelligent medicine box and the intelligent medicine box system of the present invention can realize the intelligent medicine reminder to the patient, and can also realize the function of recording the patient's medicine taking situation at the same time.

The utility model with the application number 201320368681.8 and the application date of 2013.06.25 provides an intelligent medicine box system that monitors the situation of taking medicine and provides reminder services, including a switch monitoring device for monitoring whether the switch state of the medicine box changes. The device is wirelessly connected to the gateway device module, and the gateway device module is directly connected to the user terminal through a wireless network or a wired network, or connected to a background server system, and the background server system is then connected to the user terminal through a wireless network or a wired network. The utility model has the advantages of providing better and more flexible services through the combination of the background system and the short message gateway or call center, and can also provide more functions, combined with the short-distance wireless communication technology adopted by the switch monitoring device, in the Deployment, implementation and maintenance are simpler, more convenient and easy to use, and the cost is low.

The utility model with the application number 201220625359.4 and the application date of 2012.11.23 discloses a remote network management device that can set, interact and monitor medication in real time, including a disc-shaped smart medicine box and multiple wireless remote reminder devices; The shaped smart medicine box has a disc-shaped housing and a medicine box base, and a microcomputer central processing unit, a power supply unit and a network camera are arranged in the disc-shaped housing; and a motor connected with the microcomputer central processing unit /medicine disk driving device, a safety key, a warning unit, a communication transceiver unit, a sensing unit, a storage unit for storing physiological data, a driving unit for a medicine storage temperature control device, and a state switching control unit; disk-shaped The disc-shaped casing of the smart medicine box is provided with a plurality of radially arranged fan-shaped pharmaceutical compartments. The microcomputer central processing unit is used to set, store, and time-control multiple mid-term medications. The warning unit is controlled by the microcomputer central processing unit. The time control logic of the system sends out a medicine reminder to notify the user of the medicine.

However, these existing technologies mainly solve the problem of missed doses and wrong doses caused by forgetting patients through different usage methods. In fact, long-term medication chemotherapy is a long process of treatment and recovery, which determines the patient’s medication compliance. The decisive factor is the patient's own health awareness and health management ability, how to continue to provide patients with customized one-on-one education and health services during the course of treatment, including education on treatment plans, medication knowledge, nutrition and health care, etc., review Re-examination reminders and medication reminders, as well as follow-up consultation services such as psychological counseling and question answers, have become technical problems that need to be solved urgently. Only by doing these can the medication compliance of patients treated at home be truly improved.

Contents of the invention

In view of the above problems, the object of the present invention is to provide a method for improving patient medication compliance and an intelligent medicine box system, which provides functions such as medication supervision and reminder, health education, consultation and follow-up for the patient's entire course of treatment. It is simple, easy to use, and has a very low market cost, and can help patients gradually improve, maintain, and improve medication compliance.

In order to achieve the above object, the present invention adopts the following technical solutions: a method for improving patient medication compliance, which is characterized in that it comprises the following steps: 1) an intelligent medicine box system is set, which includes an intelligent medicine box device, a cloud platform and a mobile phone APP , the intelligent medicine box device includes a central processing module, a real-time clock module, a camera module, a wireless communication module, an MP3 player module, a sensor module, a power supply charging and discharging module, a memory module, a button and a display module, a speaker and a battery, and a charging and communication interface ;2) Establish a knowledge base centered on the disease, which covers pathology and treatment plan interpretation, medication knowledge, nutrition and health care, psychological counseling, reexamination reminders, etc., and then arrange these contents at different time points in the course of treatment, The time point can be after taking the medicine every time or every day, or after taking the medicine for a certain time or day, thus forming a step-by-step health education knowledge base; 3) recording the knowledge content programmed at each time point into voice The files are named with time points, and the voice files are recorded into different language versions, and then these voice files are classified and stored according to the disease type and language type; 4) the voice files are copied to the memory card of the smart medicine box device together with the directory Above all, the central processor of the smart medicine box device will first find the corresponding coded folder in the first-level directory according to the patient's disease type parameter every time the patient takes medicine, and then find the corresponding coded file in the second-level directory according to the patient's language type parameter. Folder, finally calculate the times or days of the course of treatment or the number of days to take the medicine, retrieve the voice file with the same name as the number of times or days in the folder, and finally the central processor instructs the MP3 module to automatically play or prompt the patient to listen to the way to take the medicine Health education is carried out simultaneously in the process.

Further, in the step 4), the specific working process of the smart medicine box device is as follows: 4.1) First, configure the parameters of the medicine box, and after the parameter configuration is completed, the medicine box starts to enter the working state, and the configuration parameters will be stored in the EEPROM of the memory module Middle; 4.2) Judging whether the current date of the medicine box is within the course of treatment, if it is not within the course of treatment, it will be in a dormant state, otherwise, judge whether the current time of the medicine box is within the time interval of taking medicine, and enter the next step if it is within the time interval of taking medicine; otherwise, enter the next step 4.4) Medium; 4.3) Judging whether the current time of the medicine box has reached the reminder time, if it reaches the reminder time, then judge whether the medication value has been taken, if it has been taken, enter the dormant state, otherwise play an alarm to remind the patient to take the medicine, and enter step 4.6 ); if the reminder time is not reached, then enter step 4.5); 4.4) when the date value of the real-time clock module of the smart pill box is located in the beginning and end date of the course of treatment and the time value of the real-time clock module does not enter the time interval of taking medicine, the smart pill box The default value of the second dose status is "not taken". At this time, the patient opens the upper cover of the medicine box, and the sensor module is interrupted due to the change of magnetic force. The central processing unit will control the mp3 module to play a voice prompt to the patient "the time for taking the medicine is not up. Please take the medicine according to the doctor's advice." ", and enter the dormant state; 4.5) When the date value of the real-time clock module of the smart pill box is within the start and end dates of the course of treatment and the time value of the real-time clock module is in the time interval of taking medicine, and is in the time interval of taking medicine, the patient opens the upper cover of the medicine box , the sensor module is interrupted due to the change of magnetic force, the central processing unit will instruct the camera module to take pictures in sequence, the storage module to record the interruption time, the storage module to store the data to the memory card, and then the central processing unit calculates the number of days of the course or the day According to the number of times or days of taking medicine, search the knowledge base folder on the memory card, find the voice file in the corresponding directory with the same name as the calculated number of times or days to play or prompt the patient to listen, play an alarm to remind the patient to take the medicine, and Set the medicine taking status value as taken, enter step 4.7); 4.6) judge whether the medicine box is open, if it is opened, enter step 4.5); if not open, play the alarm once every 5 minutes, three times each time, at the same time, No photo data of taking medicine is generated, the medicine taking status value in the medicine box is still "not taken", enter step 4.8); 4.7) judge whether to use the network, if not, send a text message to the mobile phone of the doctor or guardian, and the medicine box enters Dormant state; on the contrary, if it is connected to the Internet, the photo in the memory card will be sent to the cloud platform via the wireless communication module after 5 minutes of medication interruption, and the medicine box will enter the dormant state, and step 4.8) will be executed; Start to retrieve the data file in 25 minutes, judge whether there is a data file and whether the interruption time in the data file is within 20 minutes from the start time of the medication reminder time interval to the medication reminder time, and if so, send a notification message of the taken medicine to the mobile APP, otherwise send a missed message. Service notification message to mobile APP.

Further, in the step 4.1), the parameter configuration is completed by connecting the host computer with the charging and communication interface, or downloading the parameter configuration file by connecting to the cloud platform.

Further, in the step 4.1), the parameters include the medicine box ID, the patient name, the medicine box clock, the start and end dates of the course of treatment, the total number of times of taking medicine, the time interval of each medicine taking, the reminder time, the medicine taking interval, the patient's Disease type and language, doctor's contact number and guardian's contact number.

Further, in said step 4.3), when the date value of the real-time clock module of the smart medicine box is located in the start and end date of the course of treatment and the time value of the real-time clock module reaches the reminder time, if the medicine status value in the smart medicine box has been "taken" , then the central processor of the smart medicine box will not control the mp3 module to play a reminder alarm; if the medicine status value in the smart medicine box is still "not taken", the central processor of the smart medicine box will control the mp3 module to play an alarm file to remind the patient to take the medicine At this time, if the patient opens the medicine box and triggers the sensor module to cause an interruption, the central processing unit will instruct the mp3 module to stop playing the alarm file, the camera module to take pictures, the memory module to record the interruption time, the memory module to store data to the memory card, and then The central processor calculates the number of times or days of taking the medicine for the current time or day, and then searches the knowledge base folder on the memory card to find the voice in the corresponding directory with the same name as the calculated times or days. The file is played or the patient is prompted to listen, and then the status value of the medicine in the medicine box is changed to "taken"; otherwise, the reminder bell is repeated several times to remind the patient to take the medicine.

Further, in the step 4.8), the data file includes the smart medicine box ID, interruption time and image data.

An intelligent medicine box system for realizing the above-mentioned method for improving patient medication compliance, characterized in that: the system includes an intelligent medicine box device, a cloud platform, a mobile phone APP and a database; the intelligent medicine box device passes through the cloud platform Information interaction with the mobile phone APP, the smart medicine box device realizes the functions of automatic step-by-step education, medication supervision and one-key consultation, and is connected to the cloud platform through a wireless network, or used alone; Information management, knowledge base management and data analysis of patients; the mobile phone APP software realizes intelligent medicine box parameter configuration, information query and receiving notification messages sent by the cloud platform; the cloud platform is also connected with the database, and the database Responsible for storing the patient’s file information, treatment plan, medicine box configuration information and knowledge base file information; the database receives and stores the medicine-taking behavior data uploaded by the smart medicine box device through the cloud platform, and analyzes and processes the data, and Send and push new configuration information and knowledge base voice files to the smart medicine box device; push medicine status notification information to the mobile phone APP and mobile phone.

Further, the smart medicine box device includes a housing and a central processing module, a real-time clock module, a camera module, a wireless communication module, an MP3 player module, a sensor module, a power supply charging and discharging module, a storage module, and a central processing module arranged in the housing. Button and display module, speaker and battery, and charging and communication interface; the real-time clock module, camera module, wireless communication module, MP3 player module, sensor module, power supply charging and discharging module, memory module, button and display module, speaker and The battery and the charging and communication interface are evenly connected to the central processing module, and perform information interaction with the central processing module; and each module is connected by an electronic circuit, and the electronic circuit is located in the housing and connected The connection is secured by screws.

Further, the central processing module includes a microcontroller and a memory, and the microcontroller is used to control the workflow of the entire medicine box; the memory module includes a built-in T-Flash memory card and an EEPROM chip, and the Audio files and other data files of health promotion are stored in the T-Flash memory card.

Further, the housing of the intelligent medicine box device has an upper cover, the upper cover is connected to the housing through a shaft, and a permanent magnet is arranged in the upper cover; when the upper cover is in a closed state When the permanent magnet is closest to the sensor module, the permanent magnet will attract the sensor module, the sensor module is in a closed state, and the sensor module is connected to the central processing module. The central processing module judges that the medicine box is in a closed state through processing, and controls the whole medicine box to stand by; when the upper cover is opened, the permanent magnet will be far away from the sensor module, and at this time the magnetic force weakens and the sensor module is disconnected, and the The central processing module controls each functional module to wake up, and the medicine box enters a working state.

Due to the adoption of the above technical solutions, the present invention has the following advantages: 1. The present invention organically combines health education and medication behavior, and implements automatic step-by-step education during the patient's medication process to help patients improve their awareness and ability of self-health management, thereby Achieve the goal of improving patient medication compliance. 2. The present invention only plays the alarm bell when the patient forgets through the intelligent reminder function, which can not only solve the problem of the patient forgetting but also minimize the disturbance to the patient. 3. The present invention realizes doctor-patient communication and eases doctor-patient conflicts through follow-up and consultation. The function of patient consultation is realized by sending appointment text messages, which can quickly establish contact with doctors without disturbing the work of doctors. 4. The intelligent medicine box device of the present invention can be used both stand-alone and networked. 5. The parameters of the intelligent medicine box of the present invention are set with the start and end dates of the course of treatment, which realizes the automatic start and end of the working state of the medicine box; the medicine reminder time is set The time interval and reminder time point realize the supervision and reminder of medication behavior. 6. The intelligent medicine box of the present invention records the doctor-patient call data and uploads it to the cloud platform, which can accurately count the workload of follow-up doctors. 7. The partition design of the small medicine box of the present invention provides a variety of medicine storage methods, which can be stored according to the amount of medicine taken each time or according to the type of medicine taken. 8. The present invention is simple to operate, and can be easily and conveniently used by patient groups of all ages, nationalities and languages.

Description of drawings

Fig. 1 is the structural representation of the intelligent medicine box system of the present invention;

Fig. 2 is the structural representation of the intelligent medicine box device of the present invention;

Fig. 3 is the schematic diagram of the knowledge base file directory classification and the file naming mode of the automatic step-by-step mission method of the present invention;

Fig. 4 is a schematic diagram of the workflow of the smart medicine box device of the present invention.

detailed description

The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

As shown in Figure 1, the present invention provides a smart medicine box system for improving patients' medication compliance, which includes a smart medicine box device, a cloud platform, a mobile APP and a database. The smart medicine box device conducts information interaction with the mobile phone APP through the cloud platform. The smart medicine box device realizes the functions of automatic step-by-step education, medication supervision and one-key consultation. It can be connected to the cloud platform through a wireless network or used alone; the cloud platform realizes Information management, knowledge base management and data analysis of patients; mobile phone APP software realizes intelligent medicine box parameter configuration, information query and receiving notification messages from the cloud platform. The cloud platform is also connected to the database, which is responsible for storing the patient’s file information, treatment plan and medicine box configuration information, knowledge base file information, etc.; the database receives and stores the medication behavior data uploaded by the smart medicine box device through the cloud platform and analyzes the data Processing, and sending and pushing new configuration information and knowledge base voice files to the smart medicine box device; pushing notification information such as medication status to the mobile phone APP and mobile phone. When in use, the intelligent medicine box system of the present invention organically combines health education and medication management, helps patients improve their awareness and ability of self-health management through automated step-by-step education, and solves the problem of patients forgetting through an intelligent reminder function. Key to make an appointment for consultation to achieve doctor-patient communication to ease doctor-patient conflicts, and ultimately improve patients' medication compliance.

In the above-mentioned embodiment, the mobile phone APP is connected to the cloud platform, and the login user can be a medical staff, a patient guardian, the patient himself, etc. After the user registers and logs in successfully, he can enter and modify patient-related information on the cloud platform according to the authority, and configure a smart phone for the patient. According to the parameters of the medicine box, you can view the data and reports on the cloud platform according to the authority, and receive notification information such as the status of taking medicine from the cloud platform.

In the foregoing embodiment, as shown in Figure 2, the smart medicine box device includes a housing and a central processing module, a real-time clock module, a camera module, a wireless communication module, an MP3 player module, a sensor module, and a power supply charging and discharging module arranged in the housing. , memory module, button and display module, speaker and battery, and charging and communication interface. Real-time clock module, camera module, wireless communication module, MP3 player module, sensor module, power supply charging and discharging module, storage module, button and display module, speaker and battery, and charging and communication interface uniform central processing module connection, and central processing module carry out information exchange. And each module is connected by electronic circuit, and the electronic circuit is located in the housing and fixedly connected with the housing by screws. in:

The central processing module includes a microcontroller and a memory. The microcontroller uses a high-performance 32-bit microcontroller to control the workflow of the entire medicine box; the memory module includes a built-in T-Flash memory card and an EEPROM chip. Audio files and other data files of health promotion are stored in the T-Flash memory card.

The casing of the intelligent medicine box device has an upper cover, the upper cover and the casing are connected by a shaft, and a permanent magnet is arranged in the upper cover. When the upper cover is in a closed state, the permanent magnet is closest to the sensor module on the circuit board (the sensor module can be a reed switch or a Hall sensor, preferably a reed switch in this example), and the permanent magnet will attract the sensor module , the sensor module is in a closed state, and the sensor module is connected to the central processing module. At this time, the central processing module judges that the medicine box is in a closed state through processing, and controls the overall standby of the medicine box; when the upper cover of the medicine box is opened, the permanent magnet will be far away from the sensor module. At this time, the magnetic force weakening sensor module is disconnected, the central processing module controls each functional module to wake up, and the medicine box enters the working state.

In a preferred embodiment, the built-in program of the smart pill box device can periodically send device operation status data to the cloud server, including but not limited to battery power, working status values of each module, and SIM card registration base station data. The cloud platform can use these data to achieve early warning and reminders. For example, battery power data can be used to remind guardians and patients to charge the device in time. The working status of each module can be used to monitor the operation of the device. Base station data can be used to locate the device through algorithms. Patient position and position changes.

In a preferred embodiment, a cavity for storing medicines is provided in the casing of the smart medicine box device, which is covered by an upper cover. The smart medicine box device is accompanied by a plurality of small medicine boxes that can be put into the cavity, each small There are three small baffles in the box. Patients can put the medicine together with the packaging directly into the cavity without using the small medicine box, or put different medicines into the small medicine box and then put them into the cavity according to their own needs. in:

There are two ways to use the small pill boxes. One is to fill them separately according to the type of medicine, that is, each small medicine box contains a kind of medicine, and the patient takes out the corresponding small medicine box to open it when taking it; the other is To fill according to the amount of medicine taken each time, you need to use the baffle attached to the small medicine box to separate the small medicine box first. You can use the baffle to separate the small medicine box according to the number of times you take medicine every day. The separation method is 1 grid (once a day) ), 2 grids (twice a day), 3 grids (three times a day), 4 grids (four times a day). When taking it, just take out the medicine corresponding to the small box and take it, so as to avoid the occurrence of wrong dose.

In a preferred embodiment, the camera module on the casing of the smart medicine box device is triggered by an interruption caused by the sensor module when the patient opens the box, and can take multiple photos or continuous video, and the shooting method is determined by the built-in parameter configuration of the medicine box ;The charging and communication interface can charge the rechargeable battery of the smart pill box device or supply power to the device through a transformer and rectifier power supply. The display module of the smart pill box can display the remaining power, and will prompt the user to charge when the power is insufficient. The computer is connected with the computer, and the smart medicine box device can be configured and debugged through the host computer software running on the computer; the microphone is used to collect the patient's voice during the patient's call and communication; the speaker module is used to play the sound of the smart medicine box device.

In a preferred embodiment, a display screen and a control panel are also arranged on the casing of the smart medicine box device. The display screen is used to display information such as battery power, semaphore, time, missed call prompt, unplayed voice file prompt, currently playing file name and other information; the control panel is provided with a play/pause button, a previous song button, a next song button, Help button, download doctor's order button, appointment/answer button.

In a preferred embodiment, the wireless communication module includes but not limited to GSM/GPRS communication, WIFi communication and Bluetooth communication.

The present invention also provides a method for improving patient medication compliance, which comprises the following steps:

1) Set up an intelligent medicine box system;

2) Establish a knowledge base centered on the disease. The knowledge base covers pathology and treatment plan interpretation, medication knowledge, nutrition and health care, psychological counseling, re-examination and re-examination reminders, etc., and then scientifically arrange these contents at different time points in the course of treatment , the time point can be after each (daily) medication or after a certain (certain day) medication, thus forming a stepped health education knowledge base.

3) Record the knowledge content arranged at each time point into a voice file and name it after the time point. For example, the health education content that needs to be understood when taking medicine on the tenth day is recorded into a voice file and named 010.mp3, and the Voice files can be recorded into different language versions, and then these voice files are classified and stored according to disease type and language type. The file storage directory structure and coding rules are shown in Figure 3;

In this embodiment, the first-level directory is the disease classification, and the disease classification is represented by two digits, 01 represents tuberculosis, 02 represents AIDS, 03 represents brucellosis, and so on; the second-level directory is the language category, and the language category is represented by Two digits represent, 01 represents Chinese, 02 represents Uyghur, 03 represents Tibetan, and so on.

4) Copy the voice file together with the directory to the memory card of the smart pill box device. The central processor of the smart pill box device will first find the corresponding coded folder in the first-level directory according to the patient's disease type parameters every time the patient takes medicine. , and then find the folder corresponding to the code in the secondary directory according to the patient's language type parameter, and finally calculate the number (or days) of taking the medicine for the current (or day) course of treatment, and search the folder with the same name as the number of times (number of days) Finally, the central processing unit instructs the MP3 module to automatically play or remind the patient to listen to the way to realize the synchronous health education in the process of taking medicine.

In the above step 4), as shown in Figure 4, the specific workflow of the smart medicine box device is as follows:

4.1) Before use, configure the parameters of the pill box first. The parameter configuration can be completed by connecting the host computer with the charging and communication interface, or downloading the parameter configuration file by connecting to the cloud platform. After the parameter configuration is completed, the medicine box starts to enter the working state, and the configuration parameters will be stored in the EEPROM of the memory module, and the configuration information will not be lost when the power is cut off or the battery is exhausted;

Among them, the parameters include but are not limited to the medicine box ID, patient name, medicine box clock, start and end dates of the course of treatment, total number of medicines taken, time interval of each medicine taken, reminder time, time interval between medicines taken, disease type and language of the patient Type, doctor's contact number, guardian's contact number, etc.

4.2) Judging whether the current date of the medicine box is within the course of treatment, if not within the course of treatment, it will be in a dormant state, otherwise, determine whether the current time of the medicine box is within the time interval of taking medicine, and enter the next step if it is within the time interval of taking medicine; otherwise, enter step 4.4) middle;

4.3) Judging whether the current time of the medicine box reaches the reminder time, if it reaches the reminder time, then judge whether the medication value is taken, if it is taken, enter the dormant state, otherwise play an alarm to remind the patient to take the medicine, and enter step 4.6); if not When the reminder time is reached, go to step 4.5);

4.4) When the date value of the real-time clock module of the smart pill box is within the start and end dates of the course of treatment and the time value of the real-time clock module does not enter the medication time interval, the status value of this medication in the smart pill box defaults to "not taken". At this time, the patient Open the upper cover of the medicine box, the sensor module will be interrupted due to the change of magnetic force, and the central processing unit will control the mp3 module to play a voice prompting the patient "the time for taking the medicine is not up, please take the medicine according to the doctor's advice" and enter the dormant state;

4.5) When the date value of the real-time clock module of the smart medicine box is within the start and end dates of the course of treatment and the time value of the real-time clock module is within the time interval of taking medicine, the patient opens the upper cover of the medicine box, and the sensor module causes an interruption due to a change in magnetic force, and the central processing unit will Instruct the camera module to take pictures in sequence, the storage module to record the interruption time, and the storage module to store data to the memory card, and then the central processing unit calculates the number of times (or the number of days) of the course of treatment (or the number of days) that the current time (or the day) is the number of times the medicine is taken ( number of days), retrieve the knowledge base folder on the memory card, find the voice file with the same name as the calculated number of times (number of days) under the corresponding directory to play or prompt the patient to listen, then set the medication status value as taken, and enter step 4.7);

4.6) Judging whether the medicine box is opened, if it is opened, enter step 4.5); if it is not opened, the alarm will be played every 5 minutes, three times each time, at the same time, no photo data of taking medicine will be generated, and the medicine taking status value in the medicine box Still "not accepted", go to step 4.8);

4.7) Judging whether to use the network, if not connected to the network, send the text message taken to the mobile phone of the doctor or guardian, and the medicine box enters a dormant state; otherwise, the data file in the memory card will be sent to the cloud via the wireless communication module after 5 minutes of interruption of taking the medicine platform, the medicine box enters the dormant state, and executes step 4.8);

4.8) The cloud platform starts to retrieve the data file 25 minutes after the end of the reminder time for taking the medicine prescribed by the doctor, and judges whether there is a data file and whether the interruption time in the data file is within 20 minutes from the start time of the reminder time interval of taking the medicine to the 20 minutes after the reminder time of taking the medicine. Send the notification message of the completed dose to the mobile APP, otherwise send the notification message of the missed dose to the mobile APP; the data files include the smart medicine box ID, interruption time, image data, etc.

In the above step 4.3), when the date value of the real-time clock module of the smart medicine box is within the start and end dates of the course of treatment and the time value of the real-time clock module reaches the reminder time, if the medication status value in the smart medicine box has been "taken", the smart The central processing unit of the medicine box will not control the mp3 module to play the reminder alarm. If the medicine status value in the smart medicine box is still "not taken", the central processor of the smart medicine box controls the mp3 module to play an alarm file to remind the patient to take the medicine. Instruct the mp3 module to stop playing the alarm file, the camera module to take photos, the memory module to record the interruption time, the memory module to store data to the memory card, and then the central processing unit calculates the number of times (or How many days) take the medicine to get the number of times (number of days) value, then search the knowledge base folder on the memory card, find the voice file in the corresponding directory with the same name as the calculated number of times (number of days) value to play or prompt the patient to listen, and then change the medicine box The status value of the internal medicine is "taken"; otherwise, the reminder bell will be repeated several times to remind the patient to take the medicine.

In the above steps, the smart reminder function of the smart medicine box device will only play an alarm to remind the patient when the patient forgets. If the patient obeys the will and takes the medicine on time, the smart reminder function will no longer play the reminder alarm to disturb the patient.

When the present invention is in use, the inquiry and follow-up function of the intelligent medicine box device can conveniently help patients establish contact with doctors. If the patient has a health problem during the course of treatment, he can press the appointment/answer button on the display and control module of the smart medicine box. After receiving the button information, the central processor of the smart medicine box can instruct the wireless communication module to dial the doctor's phone through the GSM network or send a call to the cloud. The platform sends a data packet in the form of a consultation request. After receiving the data packet, the cloud platform will immediately send an appointment notification message to the doctor account APP associated with the patient account or send an appointment SMS to the doctor's mobile phone, thereby realizing instant consultation or appointment consultation. Function; doctors can directly dial the phone number of the SIM card in the medicine box device according to follow-up needs, and patients can answer the doctor's follow-up call by pressing the appointment/answer button, so as to quickly realize doctor-patient communication. During the call, the smart medicine box device will store the call data on the memory card of the storage module, and the call record data includes: call direction, call start time, and call end time.

When the present invention is used, the intelligent medicine box device will check whether there is a call data file at a random time point between 0:00 and 2:00 in the morning every day, and if there is, it will be sent to the service platform immediately, and the data file will be deleted after sending; The box device conducts a self-test to obtain various operating status data, and then sends the data to the service platform.

The above-mentioned embodiments are only used to illustrate the present invention, and the structure, size, location and shape of each component can be changed. On the basis of the technical solution of the present invention, all improvements to individual components according to the principles of the present invention and equivalent transformations shall not be excluded from the protection scope of the present invention.

Claims (9)

1. A kind of 1. method for improving patient's drug compliance, it is characterised in that comprise the following steps：

   1）One intelligent medicine box system is set, and it includes intelligent medicine box device, high in the clouds platform and cell phone application, intelligent medicine box device bag Include central processing module, real-time clock module, camera module, wireless communication module, MP3 playing modules, sensor assembly, electricity Source charge-discharge modules, reservoir module, button and display module, loudspeaker and battery and charging and communication interface；

   2）Disease-based learning to establish knowledge base, knowledge base covers pathology and therapeutic scheme deciphering, knowledge on drug abuse, nutrition and guarantor Reminded contents are rechecked in strong, psychological counseling, check, and then by these content arrangements in the different time points of the course for the treatment of, time point can To be after can also being certain or the medication of certain day, to be consequently formed a stepped health education and know after each or daily medication Know storehouse；

   3）The knowledge content of upper layout of each time point is recorded into voice document and named with time point, and by voice text Part is recorded into different language versions, then by these voice documents according to disease type and language form classification classification storage；

   4）Voice document is copied on the storage card of intelligent medicine box device together with catalogue, the central processing unit of intelligent medicine box device The file of corresponding coding under first class catalogue can be found according to patient's type parameter first when patient per takes medicine, then The file of corresponding coding under second-level directory is found according to patient's language form parameter, it is the course for the treatment of finally to calculate when the secondary or same day Which time or which day medication, the interior voice document of the same name with number or number of days of retrieval file folder, last central processing unit instruction The mode that MP3 modules play automatically or prompting patient listens to, which is realized, synchronously carries out health education in drug administration process；

   The specific workflow of intelligent medicine box device is as follows：

   4.1）Parameter configuration first is carried out to medicine box, medicine box initially enters working condition after the completion of parameter configuration, and configuration parameter can be deposited Storage is in the EEPROM of reservoir module；

   4.2）Medicine box current date is judged whether in the course for the treatment of, the then resting state not in the course for the treatment of, conversely, when judging that medicine box is current Between whether in medicine time section, then enter in next step in medicine time section；Conversely, then enter step 4.4）In；

   4.3）Judge medicine box current time whether the arriving reminding time, if the arriving reminding time, judge whether medication value is Clothes, then enter resting state to have taken, otherwise play clock alarming patient medication, and enter step 4.6）；Carried if not reaching Wake up the time, then into step 4.5）；

   4.4）When intelligent medicine box real-time clock module date value is located in the beginning and end date of the course for the treatment of and real-time clock module Time value is introduced into medicine time section, and this medication state value is defaulted as " not taking " in intelligent medicine box, and now patient opens medicine Box can go up lid, and sensor assembly interrupts because magnetic force change triggers, and central processing unit can control mp3 modules to play voice message trouble Person's " medicine time does not arrive, please by medication ", and enter resting state；

   4.5）When intelligent medicine box real-time clock module date value is located in the beginning and end date of the course for the treatment of and real-time clock module Time value is located at medicine time section, and is located at medicine time section, then patient opens medicine box cover, and sensor assembly is due to magnetic Power change, which triggers, to be interrupted, central processing unit can instruct camera module to shoot photo successively, reservoir module records the break period, Reservoir module stores data into storage card, and then central processing unit is calculated when the secondary or same day is which time or which day of the course for the treatment of Medication obtains number or number of days, retrieves the knowledge Base article folder on storage card, finds number or day with calculating under corresponding catalogue Number voice document of the same name plays out or prompts patient to listen to, and plays clock alarming patient medication, and set medication state It is worth to have taken, into step 4.7）；

   4.6）Judge whether medicine box is opened, step 4.5 is entered if having opened）；If being not turned on quarter-bell was played every 5 minutes Once, every time three times, meanwhile, do not produce medication picture data, the medication state value in medicine box is still " not taking ", into step 4.8）；

   4.7）Judge whether networking, sent if not networking and taken short message to doctor or care provider's mobile phone, medicine box entrance Resting state；Otherwise networking, then medication send photo in storage card through wireless communication module after interrupting generation 5 minutes and put down to high in the clouds Platform, medicine box enters resting state, and performs step 4.8）；

   4.8）High in the clouds platform starts to retrieve data file for 25 minutes after in the medication alert time of doctor's advice terminating, and determines whether to count According to the break period in file and data file whether 20 after the medication alert time interval time started to medication alert time It is to send to have taken notification message to cell phone application, otherwise send and miss notification message to cell phone application in minute.
2. A kind of 2. method for improving patient's drug compliance as claimed in claim 1, it is characterised in that：The step 4.1） In, parameter configuration is connected host computer with communication interface using charging and completed, or by connecting high in the clouds platform download parameters configuration text Part.
3. A kind of 3. method for improving patient's drug compliance as claimed in claim 1, it is characterised in that：The step 4.1） In, parameter includes medicine box ID, patient's name, medicine box clock, the beginning and end date of the course for the treatment of, every time medication total degree, medication Time interval, reminder time, the dosing interval time, the ill type and category of language of patient, the telephone number of doctor and The telephone number of guardian.
4. A kind of 4. method for improving patient's drug compliance as claimed in claim 1, it is characterised in that：The step 4.3） In, when intelligent medicine box real-time clock module date value is located in the beginning and end date of the course for the treatment of and real-time clock module time value The arriving reminding time, if intelligent medicine box medicine for oral administration state value has been " clothes ", intelligent medicine box central processing unit will not be controlled Mp3 modules processed, which play, reminds quarter-bell；If intelligent medicine box medicine for oral administration state value is still " not taking ", intelligent medicine box central processing unit Mp3 modules are controlled to play quarter-bell document reminding patient medication, now if patient is opened in the initiation of medicine box trigger sensor module Disconnected, central processing unit can instruct mp3 modules to stop playing quarter-bell file, camera module shooting photo, reservoir module successively Record break period, reservoir module store data into storage card, and it is the course for the treatment of that then central processing unit, which was calculated when the secondary or same day, Which time or which day medication obtain number or day numerical value, retrieve the knowledge Base article folder on storage card afterwards, find corresponding mesh The lower voice document of the same name with the number of calculating or day numerical value of record plays out or prompted patient to listen to, and then changes in medicine box State value of taking medicine is " clothes "；Otherwise the tinkle of bells is repeatedly reminded to remind patient's medication.
5. A kind of 5. method for improving patient's drug compliance as claimed in claim 1, it is characterised in that：The step 4.8） In, data file includes intelligent medicine box ID, break period and view data.
6. 6. a kind of intelligent medicine box system for realizing the method that patient's drug compliance is improved as described in any one of claim 1 to 5, It is characterized in that：The system includes intelligent medicine box device, high in the clouds platform, cell phone application and database；The intelligent medicine box device warp The high in the clouds platform carries out information exchange with the cell phone application, and the intelligent medicine box device realizes automation staged propaganda and education, clothes Medicine is supervised and a key interrogation function, is connected by wireless network with the high in the clouds platform, or is used alone；The high in the clouds platform is real The now information management to patient, knowledge base management and data analysis；The cell phone application software realize intelligent medicine box parameter configuration, The notification message that information inquiry and reception high in the clouds platform are sent；The high in the clouds platform is also connected with the database, the data It is responsible for storing archive information, therapeutic scheme and the medicine box configuration information and knowledge Base article information of patient in storehouse；The database leads to The high in the clouds platform is crossed to receive and store the drug administration behavior data that the intelligent medicine box device uploads and carry out at analysis data Reason, and issue and push new configuration information and knowledge base voice document to the intelligent medicine box device；To the cell phone application and Mobile phone push medication state notification information.
7. A kind of 7. intelligent medicine box system for improving patient's drug compliance as claimed in claim 6, it is characterised in that：The intelligence Energy medicine box device includes housing and the central processing module being arranged in the housing, real-time clock module, camera module, nothing Line communication module, MP3 playing modules, sensor assembly, power supply charge and discharge module, reservoir module, button and display module, raise Sound device and battery and charging and communication interface；The real-time clock module, camera module, wireless communication module, MP3 are played Module, sensor assembly, power supply charge and discharge module, reservoir module, button and display module, loudspeaker and battery and charging Uniformly the central processing module is connected with communication interface, and information exchange is carried out with the central processing module；And each module is all Connected using electronic circuit, the electronic circuit, which is located in the housing and is screwed with the housing, to be connected.
8. A kind of 8. intelligent medicine box system for improving patient's drug compliance as claimed in claim 7, it is characterised in that：In described Centre processing module includes microcontroller and memory, and the microcontroller is used for the workflow for controlling whole medicine box；The storage Buffer module includes the T-Flash storage cards and a piece of eeprom chip built in one, is stored in the T-Flash storage cards strong Kang Xuanchuan audio file and other data files.
9. A kind of 9. intelligent medicine box system for improving patient's drug compliance as claimed in claim 7, it is characterised in that：The intelligence The housing of energy medicine box device has a upper lid, and by axis connection between the upper lid and the housing, the upper lid is interior to be set There is a permanent magnet；When the upper lid is in closure state, the permanent magnet and the sensor assembly are nearest, now described Permanent magnet can attract the sensor assembly, and the sensor assembly is in closure state, the sensor assembly with it is described in Processing module connection is entreated, now the central processing module judges that medicine box is closed by processing, and control medicine box is overall It is standby；When the upper lid is opened, the permanent magnet meeting weakens the sensor die away from the sensor assembly, now magnetic force Block disconnects, and the central processing module controls each functional module to wake up, and medicine box enters working condition.