CN106419915A - Intestinal mobility detection system based on impedance change - Google Patents
Intestinal mobility detection system based on impedance change Download PDFInfo
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- CN106419915A CN106419915A CN201611028862.0A CN201611028862A CN106419915A CN 106419915 A CN106419915 A CN 106419915A CN 201611028862 A CN201611028862 A CN 201611028862A CN 106419915 A CN106419915 A CN 106419915A
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- 238000001514 detection method Methods 0.000 title claims abstract description 35
- 230000008859 change Effects 0.000 title claims abstract description 10
- 230000000968 intestinal effect Effects 0.000 title abstract description 9
- 238000012545 processing Methods 0.000 claims abstract description 20
- 238000001914 filtration Methods 0.000 claims abstract description 8
- 230000000694 effects Effects 0.000 claims abstract description 6
- 230000004899 motility Effects 0.000 claims description 15
- 238000002847 impedance measurement Methods 0.000 claims description 10
- 230000005284 excitation Effects 0.000 claims description 8
- 230000005611 electricity Effects 0.000 claims description 7
- 230000007794 irritation Effects 0.000 claims description 6
- 229910021607 Silver chloride Inorganic materials 0.000 claims description 5
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 claims description 5
- 235000003642 hunger Nutrition 0.000 claims description 3
- 230000037351 starvation Effects 0.000 claims description 3
- 238000005259 measurement Methods 0.000 claims description 2
- 238000005086 pumping Methods 0.000 claims 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 11
- 230000002496 gastric effect Effects 0.000 abstract description 10
- 238000012544 monitoring process Methods 0.000 abstract description 4
- 230000003321 amplification Effects 0.000 abstract description 3
- 238000006243 chemical reaction Methods 0.000 abstract description 3
- 230000006378 damage Effects 0.000 abstract description 3
- 238000003199 nucleic acid amplification method Methods 0.000 abstract description 3
- 230000008991 intestinal motility Effects 0.000 abstract 2
- 238000001467 acupuncture Methods 0.000 description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000003187 abdominal effect Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 238000003745 diagnosis Methods 0.000 description 3
- 208000010643 digestive system disease Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000012806 monitoring device Methods 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 208000018685 gastrointestinal system disease Diseases 0.000 description 2
- 210000004247 hand Anatomy 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 230000008855 peristalsis Effects 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 206010067715 Gastrointestinal sounds abnormal Diseases 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000009530 blood pressure measurement Methods 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000036397 gastrointestinal physiology Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 238000000968 medical method and process Methods 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0531—Measuring skin impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
- A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
- A61B5/063—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using impedance measurements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
- A61B5/065—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
- A61B5/068—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe using impedance sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6871—Stomach
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6873—Intestine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/725—Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7253—Details of waveform analysis characterised by using transforms
- A61B5/7257—Details of waveform analysis characterised by using transforms using Fourier transforms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
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- Heart & Thoracic Surgery (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract
The invention discloses an intestinal motility detection system based on an impedance change. The intestinal motility detection system comprises a bio-impedance detecting device, and further comprises a signal processing module and a displaying module, wherein the bio-impedance detecting device is connected with the signal processing module and the displaying module; the bio-impedance detecting device comprises a transducer and an impedance detecting chip, wherein the transducer can convert an ion potential generated from electrochemical activities of living bodies into potential of a measuring system; the signal processing module comprises a signal filtration and amplification unit and an A/D conversion unit. The intestinal dynamic detection system based on the impedance change can conduct monitoring on gastrointestinal bio-impedance by a scanning drive signal generated by the bio-impedance detecting device, and can select a monitoring mode and a detection state through a mobile display interface so as to conduct a pertinent and distinctive monitoring and monitor dynamic conditions of the gastrointestinal tracts in real time. In this way, harm of the prior art to human bodies can be avoided.
Description
Technical field
The present invention relates to modern medical service detection field, particularly a kind of Instestinal motility detecting system based on impedance variation.
Background technology
Digestive tract power procuratorial theory is to the research about gastroenteropathy.For doctor physician, digestive tract is always meat
The blind area that eye cannot be seen.Since the application having fibrescope, gastroenterologist just has the honor to see digestive tract, and knows
Whether pathological changes.But whereby can not be fully solved problem, some gastrointestinal function diseases, especially power abnormality disease,
It is not can determine that diagnosis according to vision finding.Due to the numerous studies to gastrointestinal physiology, thus establishing much new
Technology, such as pH monitoring, gastrointestinal pressure measurement and clectrogastrogram, these new techniques have become the routine of gastroenteropathy research all over the world
Method.
Gastrointestinal tract medical information can reflect that gastrointestinal tract dyskinesiss disease physiological and pathological changes situation, to digestive system disease
Disease early stage diagnosis and treatment and prevent Alimentary malignant change significant.At present, clinical acquisition gastrointestinal tract medical information
Diagnostic instrumentss, need the early stages such as bowel relieving, fasting to process, patient suffering is big, detection has blind area, and detection data is not normally to give birth to
Data under reason state, these factors lead to medical circle for a long time gastroenteritic power function disease cannot be made Accurate Diagnosis and
Accurate treatment, cannot timely, comprehensive, objective, scientifically evaluate gastrointestinal tract dynamia function.
A kind of assistant officer's convenient, fast equipment that gastrointestinal tract is monitored to appear.
Content of the invention
A kind of Instestinal motility detecting system based on impedance variation that the present invention provides, its object is to provide a kind of letter
Just, fast, effective gastrointestinal tract monitoring device.
The technical scheme is that and be achieved in that：A kind of Instestinal motility detecting system based on impedance variation, including
Bio-impedance detection means, also includes signal processing module and display module, and described bio-impedance detection means connects at signal
Reason module and display module；Described bio-impedance detection means includes the ionic potential that can produce organism electrochemical activity
It is converted into transducer and the impedance measurement chip of measuring system current potential；Described signal processing module includes signal filtering and amplifies list
Unit, A/D converting unit.
Further, described impedance measurement chip is to produce the impedance survey that scanning and excitation signal enters row energization to transducer
Amount chip.
Further, described scanning and excitation signal is low frequency sinusoidal scanning signal.
Preferably, described display module is display interface of mobile phone, and described signal processing module passes through bluetooth connection mobile phone.
Preferably, described signal processing module also includes detection pattern unit and detection state cell；Described detection pattern
Unit includes no electricity irritation and has electricity irritation；Described detection state cell includes starvation, normal and have one's mind filled with.
Preferably, described transducer is the silver chloride electrode being pasted onto on paster by conducting resinl.
A kind of Instestinal motility detecting system based on impedance variation that the present invention provides, is sent out by bio-impedance monitoring device
Raw scanning and excitation signal is monitored to gastrointestinal bio-impedance, and is monitored pattern and detection by display interface of mobile phone
State is selected, specific aim, distinctive be monitored, at-once monitor gastrointestinal power situation, and avoid prior art
Injury to human body.
Brief description
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, below will be to embodiment or existing
Have technology description in required use accompanying drawing be briefly described it should be apparent that, drawings in the following description be only this
Some embodiments of invention, for those of ordinary skill in the art, without having to pay creative labor, also may be used
So that other accompanying drawings are obtained according to these accompanying drawings.
Fig. 1：Present configuration schematic diagram.
In figure：10th, bio-impedance detection means；11：Transducer；12nd, impedance measurement chip；20th, signal processing module；
21：Signal filtering amplifying unit；22：A/D converting unit；23：Detection pattern unit；24：Detection state cell；30th, show mould
Block.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation description is it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of not making creative work
Embodiment, broadly falls into the scope of protection of the invention.
A kind of Instestinal motility detecting system based on impedance variation disclosed in this invention, including bio-impedance detection means
10, also include signal processing module 20 and display module 30, described bio-impedance detection means 10 connects signal processing module 20
With display module 30；The ionic potential that described bio-impedance detection means 10 includes to produce organism electrochemical activity turns
Change transducer 11 and the impedance measurement chip 12 of measuring system current potential into；Described signal processing module 20 includes signal filtering and amplifies
Unit 21, A/D converting unit 22.
Further, described impedance measurement chip 12 is to produce the resistance that scanning and excitation signal enters row energization to transducer 11
Anti- measurement chip 12.
Further, described scanning and excitation signal is low frequency sinusoidal scanning signal.
Preferably, described display module 30 is display interface of mobile phone, and described signal processing module 20 passes through bluetooth connection handss
Machine.
Preferably, described signal processing module 20 also includes detection pattern unit 23 and detection state cell 24；Described inspection
Survey mode unit 23 to include no electricity irritation and have electricity irritation；Described detection state cell 24 includes starvation, normal and have one's mind filled with.
Preferably, described transducer 11 is the silver chloride electrode being pasted onto on paster by conducting resinl.
The resistance antinoise signal being extracted from human body epigastrium body surface using bio-electrical impedance technology, not only contains the intestinal of routine
Gastric peristalsis frequecy characteristic, and carry the deeper information of reflection gastrointestinal motivity situation.Extract and analyze these information,
Detection to gastrointestinal motivity is significant with evaluation.
Instestinal motility is related to some human acupoints, such as：Tsu san li, Shangjuxu, Xiajuxu cave.And human acupoint is straight
Leakage resistance and AC impedance are all low than non-acupuncture point point, it is believed that its low-resistance on the premise of still there be no evidence to suggest the essence of channels and collaterals
Anti- characteristic is not only a certain to organism or few kinds of tissues is related, and it is more likely that whole coefficient knot of organizational structure
Really.Thus when studying acupuncture point electrical characteristics, measuring system should be able to reflect the change of acupuncture point deep tissues.
Acupuncture point low-frequency electrostimulating and acupuncture at Zusanli Shangjuxu all can substantially shorten abdominal post-operation micturition time, curative effect
It is substantially better than matched group.And acupuncture point low-frequency electrostimulating and acupuncture group compare curative effect there was no significant difference, acupuncture treatment belongs to motherland
Traditional medical method, belongs to store period, and patient's sensation compared with pain, is also easy to produce fear, increases the risk of infection.
The present invention passes through to gather the intestines and stomach impedance and the intestines and stomach signal of telecommunication, and it is carried out with signal processing is judged and show.
Using low-frequency electrostimulating tsu san li, Shangjuxu, Xiajuxu cave, by detecting abdominal part acupuncture point related to intestinal, particularly Pishu,
The acupuncture points such as the middle part of gastric cavity, Zhangmen, Tianshu, Qihai, Guan Yuan, the resistance antinoise signal in back acupuncture point related to intestinal san chiao shu cave, a chlorine
Change silver electrode in abdominal acupoints, another silver chloride electrode is placed on back point.By comparative experimentss object in empty stomach, satisfy
When swollen, diarrhoea, the similarities and differences of electrical impedance, indirectly judge the strong and weak fine or not of Instestinal motility.Main basis has or not borborygmus
Sound, the power of sound, whether stool is unobstructed, and number of times is how many, is contrasted with impedance matter, as when empty stomach, resistance value is low full
When swollen, when resistance value height, diarrhoea, resistance value is low, judges the strong and weak quality of power by this mode.
The present invention adopts AD5933 impedance measurement chip 12, one voltage output pin Vout, can send certain frequency
The sinusoidal scanning signal of rate enters row energization to outside impedance Z (ω).Signal is after tested organism more amplified, after filtering
Sampled by analog-digital converter, and carry out discrete Fourier transform, calculate resistance value to be measured.
AD5933 impedance measurement chip 12 is to produce sinusoidal scanning signal by the DDS of chip internal, these signals
Initial frequency, the increment of frequency and increased number of times all can be set by mobile phone.Scanning and excitation signal is by tested impedance
Afterwards, the digital signal exporting through amplification, filtering and A/D conversion is directly entered digital signal processor and carries out discrete fourier change
Change.Can also be filtered using low-pass filter circuit, then pass through wavelet transformation, specifically, the signal of collection be comprise breathing,
The mixed signals such as blood flow signal, strength ratio intestinal signal is higher, and extracting intestinal peristalsis promoting signal from above-mentioned signal is intestinal signal,
Can be analyzed by time domain, frequency domain, finally data be changed by A/D, shown by display interface of mobile phone.
In use, by bluetooth connection mobile phone, by display interface of mobile phone to detection pattern unit 23 and detection
State cell 24 is selected；Particularly to no electricity irritation with have electrical stimulation pattern and hungry, normal carry out with the state of having one's mind filled with
Corresponding selection；
It is pasted onto the silver chloride electrode abdominal part as tested organism and the back intestinal respectively on paster by conducting resinl
Related acupuncture point；
Low frequency sinusoidal scanning signal is produced by impedance measurement chip 12 and encourages outer electrode；
The gastrointestinal tract model that signal processing module 20 collects to electrode carries out signal filtering amplification, A/D conversion, and in handss
Show on machine display interface.
A kind of Instestinal motility detecting system based on impedance variation that the present invention provides, by bio-impedance monitoring device 10
Occur scanning and excitation signal that gastrointestinal bio-impedance is monitored, and pattern and inspection are monitored by display interface of mobile phone
Survey state is selected, specific aim, distinctive be monitored, at-once monitor gastrointestinal power situation, and avoid existing skill
The injury to human body for the art.
Certainly, in the case of without departing substantially from present invention spirit and its essence, those of ordinary skill in the art should be permissible
Various corresponding changes are made according to the present invention and deforms, but these corresponding changes and deformation all should belong to appended by the present invention
Scope of the claims.
Claims (6)
1. a kind of Instestinal motility detecting system based on impedance variation, including bio-impedance detection means it is characterised in that：Also wrap
Include signal processing module and display module, described bio-impedance detection means connects signal processing module and display module；Described
The ionic potential that bio-impedance detection means includes to produce organism electrochemical activity is converted into measuring system current potential
Transducer and impedance measurement chip；Described signal processing module includes signal filtering amplifying unit, A/D converting unit.
2. a kind of Instestinal motility detecting system based on impedance variation according to claim 1 it is characterised in that：Described resistance
Anti- measurement chip is to produce the impedance measurement chip that scanning and excitation signal enters row energization to transducer.
3. a kind of Instestinal motility detecting system based on impedance variation according to claim 2 it is characterised in that：Described sweep
Retouching pumping signal is low frequency sinusoidal scanning signal.
4. a kind of Instestinal motility detecting system based on impedance variation according to any one in claim 13, its
It is characterised by：Described display module is display interface of mobile phone, and described signal processing module passes through bluetooth connection mobile phone.
5. a kind of Instestinal motility detecting system based on impedance variation according to claim 4 it is characterised in that：Described letter
Number processing module also includes detection pattern unit and detection state cell；Described detection pattern unit includes no electricity irritation and has electricity
Stimulate；Described detection state cell includes starvation, normal and have one's mind filled with.
6. a kind of Instestinal motility detecting system based on impedance variation according to claim 5 it is characterised in that：Described change
Can device be the silver chloride electrode being pasted onto on paster by conducting resinl.
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| CN201611028862.0A CN106419915A (en) | 2016-11-18 | 2016-11-18 | Intestinal mobility detection system based on impedance change |
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| CN201611028862.0A CN106419915A (en) | 2016-11-18 | 2016-11-18 | Intestinal mobility detection system based on impedance change |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108742540A (en) * | 2018-06-27 | 2018-11-06 | 重庆金山医疗器械有限公司 | Automatic identification stomach esophagus swallows device and method |
| CN108836273A (en) * | 2018-06-27 | 2018-11-20 | 重庆金山医疗器械有限公司 | Esophageal dynamic function evaluation system and method |
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