CN104939825A - Wearable electrical impedance tomography gastric motility information extracting device and method - Google Patents
Wearable electrical impedance tomography gastric motility information extracting device and method Download PDFInfo
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- CN104939825A CN104939825A CN201510357132.4A CN201510357132A CN104939825A CN 104939825 A CN104939825 A CN 104939825A CN 201510357132 A CN201510357132 A CN 201510357132A CN 104939825 A CN104939825 A CN 104939825A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0536—Impedance imaging, e.g. by tomography
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/42—Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
- A61B5/4222—Evaluating particular parts, e.g. particular organs
- A61B5/4238—Evaluating particular parts, e.g. particular organs stomach
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6823—Trunk, e.g., chest, back, abdomen, hip
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6831—Straps, bands or harnesses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
Abstract
The invention discloses a wearable electrical impedance tomography gastric motility information extracting device. The wearable electrical impedance tomography gastric motility information extracting device comprises an electrode array belt, a switch array, an impedance signal measurement module, a DSP and a wireless data transmission module. The electrode array belt is composed of a pasting strip and electrode buckles distributed on the belt at equal intervals and is connected with the switch array through a wire. The switch array is composed of an excitation gating switch and a measurement gating switch. An excitation current source is composed of a DDS multi-frequency signal generation unit and a voltage and current conversion module, and excitation current is injected in a corresponding electrode pair of the electrode array belt through the excitation gating switch. The impedance signal measurement module is composed of an instrumentation amplifier, a programmable amplifier, a demodulator and an AD conversion module. The measurement gating switch picks up impedance signals of the corresponding electrode pair on the electrode array belt and converts the impedance signals into digital information, and the DSP uploads the generated digital information to a portable intelligent device through the wireless data transmission module for processing.
Description
Technical field
The invention belongs to biomedical signals measuring field, particularly relate in peptic digestion process and carry out gastric motility signal detection by wearable bio-electrical impedance imaging system.
Background technology
Gastrointestinal motility disorders is common clinical, has had a strong impact on the work of people, studying and living quality.There are some researches show, there is gastric motility extremely in the gastrointestinal disease patient of 50%, and disease of stomach is always from gastric motility disorder, and to malignization future development, and extremely with gastric motility, gastric motility is one of source of gastrointestinal disease extremely always.Motility of stomach comprises the contraction of stomach, wriggling rule and the measurement in gastric emptying time.At home and abroad in more existing detection methods, chamber internal pressure measurement, barostat inspection etc. can be observed the pressure wave caused by gastric peristalsis.But will to gastric intubation when measuring, patient not easily accepts; Radionuclide breath test, particularly scintigraphy, it is quantitative, repeatability is better, is the goldstandard that current gastric emptying is measured.But because using nucleic, patient is harmful to, and expensive, also should not for a long time, repeatedly use, its application is restricted; Ultrasonic method can be observed the situation of gastric emptying or stomach motion.But be used for the long-time inspection of digestion process, operating technology also exists many difficulties, and the existence of gastric gas can affect acoustic beam propagation, interference imaging results; Electrogastrogram (EGG) noinvasive, convenience, with the good relationship of stomach contraction frequency, can be used for studying and evaluating the disease relevant with stomach rhythmicity, but it and stomach shrink or the relatedness of moving not by force, its correlational study for gastric motility evaluation need deep.In addition, above each existing inspection method mostly can only provide one, two index, is difficult to reflect gastric motility and digestive physiology, pathological change rule fully and effectively.
Electrical impedance tomography (electrical impedance tomography, hereinafter referred to as EIT) with the electrical impedance characteristics of tissue, organ and be changed to foundation, by being configured at the electrod-array of body surface, extract the tissue relevant to Human Physiology, pathological state or the electrical characteristics information of organ, provide the functional image result of response organization, organ dysfunction state and Changing Pattern thereof.Stomach is that human body internal ratio is easier to one of organ extracting electrical impedance information, in the active stage of stomach, as gastric emptying or stomach shrink, wriggle time, because the change of the form of stomach, volume and content thereof composition situation is larger, its electrical property change clearly, Changing Pattern is corresponding with gastric motor disovder situation, and dependency is strong.EIT technology is by pasting a circle electrode at human stomach's body surface map section, a faint current excitation is applied by pair of electrodes, then remaining electrode is measured to the magnitude of voltage of upper correspondence, switch pair of electrodes again to encourage, and measure the magnitude of voltage of remaining electrode to upper correspondence, repeat down, the magnitude of voltage under one group of current excitation can be recorded, according to measuring the one group of magnitude of voltage obtained, the distribution of conductivity in gastric portion or the distribution of conductivity variations can be reconstructed by certain restructing algorithm, can noinvasive, detect the motor message of stomach continuously, extract the electrical characteristics corresponding with gastric motor disovder situation and change information thereof, the contraction of reaction stomach, wriggle and evacuation procedure, thus reach test and repair gastric motor function.
Because stomach motion and gastric emptying are processes slowly, adopted EIT to carry out motility of stomach often needs patient to stop for a long time before instrument and equipment in the past, by wire connections table electrod-array and end message extraction element, Body surface impedance information will be collected by the mode of USB or serial ports again to upload computer and carry out graphical analysis, patient is often needed to diagnose in the instrument and equipment room that hospital is special, As time goes on, the sense of discomfort of patient strengthens.Some gastric motility disorder patient is exactly because do not go to hospital seek medical advice and delayed golden hour in time, and then develops into gastritis, gastric ulcer even gastric cancer.
In recent years, along with the development of wireless communication technique and Internet technology, wearable armarium presents blowout formula and increases.Wearable device have simple to operation, by site condition restriction, low in energy consumption, facilitate the advantages such as remote monitoring.Physiological pathology of human body information can be uploaded mobile phone in time by Wearable device, information processing is carried out by the processor of mobile phone, and by network, data result is sent to the net data terminate of doctor, doctor can propose diagnostic comments according to network data information, and patient just can obtain the diagnostic result of doctor at home in time.
Wearable armarium is mainly applied to life sign measurement aspect at present, such as: Wrist-cuff device, cardiac monitor, blood glucose meter, pulse monitor, and the wearable sport and fitness product of PlayGear Stealth, arm straps or wrist strap; So far also do not have and utilize wearable armarium for forming the extraction element providing long-continued gastric motility signal of bio-electrical impedance imaging in human stomach digestion process.
Summary of the invention
For prior art, in order to solve the problems of the technologies described above, the present invention proposes a kind of wearable electrical impedance tomography gastric motility information extraction element, can the gastric motility information of long-continued acquisition wearer, thus provides basic data accurately for electrical impedance tomography.
In order to solve the problems of the technologies described above, a kind of wearable electrical impedance tomography gastric motility information extraction element of the present invention, comprise elasticity elastic waist band and portable intelligent device, described elasticity elastic waist band is provided with electrod-array, and described electrod-array comprises 8 or 16 electrode buttons of equidistantly arrangement, this device also comprises the switching gate array be integrated on one piece of circuit board, multi-frequency excitation current source, impedance signal measurement module, DSP signal processor unit and wireless data transfer module, described circuit board is provided with 8 or 16 union joints, described switching gate array comprises the excitation gating switch for exciting electrode gating and the measurement gating switch for measurement electrode gating, described excitation gating switch and described measurement gating switch are made up of 2 or 4 analog switching ic DG412 respectively, and the quantity measuring gating switch is equal with excitation gating switch quantity, described multi-frequency excitation current source comprises DDS multi-frequency signal generator and Voltage to current transducer module, described DDS multi-frequency signal generator is made up of the DDS chip of ADI company, and described Voltage to current transducer module adopts chip current mirror option A D844 based on ADI company or differential amplifier current source side case AD8130, described impedance signal measurement module comprises preposition instrument amplifier, programmable amplifier, AC-DC demodulator and AD conversion module, described preposition instrument amplifier selects the instrument amplifier of ADI company, described programmable amplifier selects the product of ADI company or TI company, ADI company root-mean-square value detection chip selected by described AD-DC demodulator, described AD conversion module selects ADI company or 16, TI company or 24 AD conversion chip, described DSP unit selects the DSP process chip of TI company, described wireless data transfer module adopts the transmission system based on bluetooth more than 4.0 chip, electrode button on described elasticity elastic waist band is connected with the union joint on described circuit board by standard lead line, each union joint is also connected with the output of the way switch encouraged in gating switch with the input of the way switch measured in gating switch respectively, and the state being decided electrode by the control of switch is for excitation or measures, DDS multi-frequency signal generator described in the IO port controlling of described DSP unit produces the ac voltage signal for encouraging, this ac voltage signal is input to the signal input part of Voltage to current transducer module, through Voltage to current transducer, export the excitation current source of satisfying the demand, the excitation current source of generation is injected into the input of each way switch of excitation gating switch, detecting electrode to be transported to preposition instrument amplifier signal input part to upper voltage signal is picked up successively by measuring the gating of gating switch, the input of programmable amplifier is transported to through the signal of enlarge leadingly, by the IO port controlling programming amplifying multiple of DSP unit, signal is through programming amplifying, to export and the input being transported to AC-DC demodulator carries out AC-DC converts d. c. voltage signal at the outfan of programmable amplifier, this voltage signal is directly inputted to the input end of analog signal of AD conversion module, DSP unit controls AD conversion module is carried out data conversion and reads transformation result, the transformation result of AD conversion module is uploaded portable intelligent device by DSP unit controls wireless data transfer module simultaneously.
Utilize above-mentioned wearable electrical impedance tomography gastric motility information extraction element to carry out the method for information retrieval, comprise the following steps:
Step one, the elasticity elastic waist band with electrod-array is placed in the body surface projection area of wearer's abdominal part stomach, by bonding strip, elasticity elastic waist band is connected to form endless belt, buckles at each electrode of elasticity elastic waist band and be provided with the disposable electrocardioelectrode of a standard respectively;
Step 2, described DSP signal processor unit control DDS multi-frequency signal generator generation amplitude is variable, the ac voltage signal of frequency-adjustable, and Voltage to current transducer module converts this ac voltage signal to excitation current source; Successively exciting current is injected in the pair of electrodes of elasticity elastic waist band by described excitation gating switch,
The impedance signal that on step 3, described measurement gating switch pickup elasticity elastic waist band, respective electrode is right;
Step 4, described preposition instrument amplifier once pick up amplification to the impedance signal on this electrode pair, programmable amplifier carries out secondary programming amplifying to the impedance signal once amplified, separate through AC-DC successively through the impedance signal of twice amplification and be in harmonious proportion AD conversion and become the digital signal of DSP signal processor unit identification, and this digital signal is passed on portable intelligent device through wireless data transfer module carry out date processing.
Compared with prior art, the invention has the beneficial effects as follows:
(1) human stomach's dynamic Information can be uploaded portable intelligent device by this wearable electrical impedance tomography gastric motility information extraction element in time, information processing is carried out by the processor of portable intelligent device, and by network, data result is sent to the net data terminate of doctor, doctor can propose diagnostic comments according to network data information, patient just can obtain the diagnostic result of doctor at home in time, facilitates the diagnosis of seeking medical advice of disease of stomach patient;
(2) by electrical impedance imaging detecting electrode being evenly distributed on a wearable elasticity degree of tightness electrod-array belt, enable the contact that detecting electrode and skin are fully good, reduce because electrode places the uneven impact on rebuilding image, image reconstruction effect repeatability, concordance are good;
(3) be integrated on a less circuit board by detecting automatically controlled, control circuit, communicating circuit etc., and be arranged on a detection box that can be placed in it, shorten the distance between electrode and testing circuit greatly, decrease because distribution capacity, distributed inductance and various electromagnetic interference on wire are on the impact of impedance measurement precision;
(4) this wearable electrical impedance tomography gastric motility information extraction element can be convenient to disease of stomach patient continuous monitoring gastric motility information, can propose diagnostic comments, convenient, flexible use according to long-term gastric motility information testing result continuously.
Accompanying drawing explanation
Fig. 1 is wearable electrical impedance tomography gastric motility information extraction element structure chart;
Fig. 2-1 is instantaneous picture after experimental example drinking-water, Fig. 2-2 is images after experimental example is drunk water 4 minutes, and Fig. 2-3 is images after experimental example is drunk water 8 minutes, and Fig. 2-4 is images after experimental example is drunk water 12 minutes, Fig. 2-5 is images after experimental example is drunk water 16 minutes, and Fig. 2-6 is images after experimental example is drunk water 20 minutes;
Fig. 3 is experimental example gastric emptying time curve chart;
Fig. 4 is that experimental example stomach moves rhythm and pace of moving things figure.
Detailed description of the invention
Be described in further detail technical solution of the present invention below in conjunction with the drawings and specific embodiments, described specific embodiment only explains the present invention, not in order to limit the present invention.
As shown in Figure 1, the present invention's wearable electrical impedance tomography gastric motility information extraction element, comprises wearable elasticity elastic waist band 1, switching gate array 2, multi-frequency excitation current source 3, impedance signal measurement module 4, DSP unit 5 and wireless data transfer module 6 that one is provided with electrod-array.
Described elasticity elastic waist band is provided with electrod-array, and described electrod-array comprises 8 or 16 electrode buttons of equidistantly arrangement.
Described switching gate array 2, multi-frequency excitation current source 3, impedance signal measurement module 4, DSP signal processor unit 5 and wireless data transfer module 6 are integrated on one piece of circuit board, and described circuit board is provided with 8 or 16 union joints; This circuit board can be arranged in the can of a long 10cm, wide 6cm, high 3cm, and this can be carried on the arm easily on waist or be placed in pocket.
Described switching gate array 2 comprises the excitation gating switch for exciting electrode gating and the measurement gating switch for measurement electrode gating; Described excitation gating switch and described measurement gating switch are made up of 2 or 4 analog switching ic DG412 respectively, and the quantity measuring gating switch is equal with excitation gating switch quantity;
Described multi-frequency excitation current source 3 comprises DDS multi-frequency signal generator and Voltage to current transducer module, and described DDS multi-frequency signal generator is made up of the DDS chip of ADI company, can adopt AD9832 chip or AD9850 chip.
Described Voltage to current transducer module adopts chip current mirror option A D844 based on ADI company or differential amplifier current source side case AD8130.
Described impedance signal measurement module 4 comprises preposition instrument amplifier, programmable amplifier, AC-DC demodulator and AD conversion module; Described preposition instrument amplifier selects the instrument amplifier of ADI company, can be a in AD8421 chip, AD8221 chip and AD8220 chip; Described programmable amplifier selects the product of ADI company or TI company, can be a in THS7001, THS7002 and AD8251; ADI company root-mean-square value detection chip selected by described AD-DC demodulator, can be that ADI company root-mean-square value detects AD637 chip; Described AD conversion module selects ADI company or 16, TI company or 24 AD conversion chip, can be ADS1274 or ADS1278 chip.
Described DSP unit 5 selects the DSP process chip of TI company, can TMS320C5509 chip.
Described wireless data transfer module 6 adopts the transmission system based on bluetooth more than 4.0 chip; Described portable intelligent device is mobile phone, panel computer, intelligent watch or Intelligent bracelet.
Electrode button on described elasticity elastic waist band is connected with the union joint on described circuit board by standard lead line, each union joint is also connected with the output (output of the way switch namely on DG412) of the way switch encouraged in gating switch with the input (input of the way switch namely on DG412) of a way switch of measuring in gating switch respectively, and the state being decided electrode by the control of switch is for excitation or measures.
DDS multi-frequency signal generator described in the IO port controlling of described DSP unit 5 produces the ac voltage signal for encouraging, this ac voltage signal is input to the signal input part of Voltage to current transducer module, through Voltage to current transducer, export the excitation current source of satisfying the demand, the excitation current source of generation is injected into the input (namely for encouraging each road input of the DG412 of gating) of each way switch of excitation gating switch.
Detecting electrode to be transported to preposition instrument amplifier signal input part to upper voltage signal is picked up successively by measuring the gating of gating switch, the input of programmable amplifier is transported to through the signal of enlarge leadingly, by the IO port controlling programming amplifying multiple of DSP unit, signal is through programming amplifying, to export and the input (ADI company root-mean-square value detection chip) being transported to AC-DC demodulator carries out AC-DC converts d. c. voltage signal at the outfan of programmable amplifier, this voltage signal is directly inputted to the input end of analog signal of AD conversion module, DSP unit controls AD conversion module is carried out data conversion and reads transformation result, the transformation result of AD conversion module is uploaded portable intelligent device by DSP unit controls wireless data transfer module simultaneously.
Utilize the concrete steps of the present invention's wearable electrical impedance tomography gastric motility information extraction element as follows:
Step one, wearable elasticity degree of tightness electrod-array belt 1 is placed in the body surface projection area of wearer's abdominal part stomach, elasticity degree of tightness electrod-array belt is buckled (quantity is 8 or 16) by bonding strip and the electrode be equidistantly distributed on belt and is formed, belt is wide 5cm, the elasticity degree of tightness bandage of long 50cm or 70cm or 90cm tri-kinds of models (large, medium and small), on bandage, evenly distributed equidistant 8 or 16 electrodes are buckled, during detection, disposable for standard electrocardioelectrode is placed in electrode to buckle, is connected to form endless belt by bonding strip;
Step 2, described DSP signal processor unit control DDS multi-frequency signal generator generation amplitude is variable, the ac voltage signal of frequency-adjustable, and Voltage to current transducer module 8 converts this ac voltage signal to excitation current source; Successively exciting current is injected into successively in the pair of electrodes of elasticity elastic waist band by described excitation gating switch and wire,
The preposition instrument amplifier of step 3, impedance signal measurement module picks up by measuring gating switch the impedance signal that on elasticity degree of tightness electrod-array belt, respective electrode is right successively, for adjacent actuators measurement pattern: set number of electrodes as n, number of electrodes is 8 or 16 in the present embodiment, when electrode 1-2 is exciting electrode, measure 3-4,4-5 ... (n-1) voltage of the electrode pair such as-n; Then replace exciting electrode 2-3, measures 4-5,5-6 ... (n-1) voltage of the electrode pair such as-n, n-1, the once complete DATA REASONING of order obtains the individual impedance voltage value of n* (n-3) altogether successively;
Step 4, described preposition instrument amplifier once picks up amplification to the impedance signal on this electrode pair, programmable amplifier carries out secondary programming amplifying to the impedance signal once amplified, the AC impedance signal amplified by secondary through AC-DC demodulator successively through the impedance signal of twice amplification converts the direct current signal meeting AD sampling to, AD conversion module converts this direct current signal to DSP unit discernible digital information, and by DSP unit, the transformation result of AD conversion module is uploaded on portable intelligent device by wireless data transfer module, and carry out date processing.
Embodiment of the present invention breaker in middle gating array is made up of 8 or 16 analog switching ic DG412, and wherein 4 or 8 are for exciting electrode gating, and other 4 or 8 are for measurement electrode gating; In multi-frequency excitation current source, DDS multiple-frequency signal generating unit forms (such as AD9832 by ADI company DDS chip, AD9850), Voltage to current transducer module adopts based on the chip current mirror scheme (AD844) of ADI company or differential amplifier current source side case (AD8130); The preposition instrument amplifier of impedance signal measurement module selects ADI company instrument amplifier (such as AD8421, AD8221, AD8220 etc.), programmable amplifier selects the product of ADI company or TI company (such as: THS7001, THS7002, AD8251 etc.), ADI company root-mean-square value detection chip (such as AD637 etc.) selected by AD-DC demodulator, AD conversion module selects ADI company or 16, TI company or 24 AD conversion chip (such as the ADS1274 of TI company, ADS1278 etc.); DSP unit selects the DSP process chip (as TMS320C5509) of TI company, and wireless data transfer module is selected and supported bluetooth 4.0 and above chip.
Adopt the present invention's wearable electrical impedance tomography gastric motility information extraction element and method, to an example empty stomach in the morning volunteer of more than 8 hours, drink 400ml temperature boiled water, carry out the image testing gained, and draw emptying curve according to image result, the one piece of data simultaneously intercepting wherein 2 minutes carries out stomach and moves the rhythm and pace of moving things and calculate, result is as Fig. 2-1, Fig. 2-2, Fig. 2-3, Fig. 2-4, shown in Fig. 2-5 and Fig. 2-6, wherein, Fig. 2-1 shows the rear instantaneous picture of drinking-water, Fig. 2-2 shows drinking-water image after 4 minutes, Fig. 2-3 shows drinking-water image after 8 minutes, Fig. 2-4 shows drinking-water image after 12 minutes, Fig. 2-5 shows drinking-water image after 16 minutes, Fig. 2-6 shows drinking-water image after 20 minutes.Fig. 3 shows gastric emptying time curve chart, and Fig. 4 shows stomach and moves rhythm and pace of moving things figure.
The present invention's wearable electrical impedance tomography gastric motility information extraction element and method is adopted to carry out the test of liquid gastric motility to 10 Healthy Youth schoolboys.Need more than 8 hours on an empty stomach before each tester tests, test-meal is 400ml temperature boiled water.Adopt apparatus of the present invention, carry out data message extraction, and upload mobile phone analysis, show that 10 tested emptying times are all within 20 ± 2 minutes, it is per minute at 2.5-3.5 time that stomach moves the rhythm and pace of moving things.
Adopt the present invention's wearable electrical impedance tomography gastric motility information extraction element and method, to an example empty stomach in the morning volunteer of more than 8 hours, drink 400ml temperature boiled water, carry out the image testing gained, and draw emptying curve according to image result, the one piece of data simultaneously intercepting wherein 2 minutes carries out stomach and moves the rhythm and pace of moving things and calculate, result is as Fig. 2-1, Fig. 2-2, Fig. 2-3, Fig. 2-4, shown in Fig. 2-5 and Fig. 2-6, wherein, Fig. 2-1 shows the rear instantaneous picture of drinking-water, Fig. 2-2 shows drinking-water image after 4 minutes, Fig. 2-3 shows drinking-water image after 8 minutes, Fig. 2-4 shows drinking-water image after 12 minutes, Fig. 2-5 shows drinking-water image after 16 minutes, Fig. 2-6 shows drinking-water image after 20 minutes.Fig. 3 shows gastric emptying time curve chart, and Fig. 4 shows stomach and moves rhythm and pace of moving things figure.
Adopt the present invention wearable electrical impedance tomography gastric motility information extraction element can noinvasive, detect gastric content electrical characteristics signal continuously, extract the electrical characteristics corresponding with gastric motor disovder situation and change information thereof, react the contraction of stomach, wriggling and evacuation procedure, thus reach test and repair gastric motor function.Adopt the present invention's wearable electrical impedance tomography gastric motility information extraction element can extract emptying information stomach function regulating movable information simultaneously, compensate for the shortcoming that existing motility of stomach equipment Inspection information is single, have flexibly simple, convenient simultaneously, abundant information, to patient without any injury and side effect.
Although invention has been described by reference to the accompanying drawings above; but the present invention is not limited to above-mentioned detailed description of the invention; above-mentioned detailed description of the invention is only schematic; instead of it is restrictive; those of ordinary skill in the art is under enlightenment of the present invention; when not departing from present inventive concept, can also make a lot of distortion, these all belong within protection of the present invention.
Claims (10)
1. a wearable electrical impedance tomography gastric motility information extraction element, comprises elasticity elastic waist band (1) and portable intelligent device, it is characterized in that,
Described elasticity elastic waist band is provided with electrod-array, and described electrod-array comprises 8 or 16 electrode buttons of equidistantly arrangement;
This device also comprises the switching gate array (2) be integrated on one piece of circuit board, multi-frequency excitation current source (3), impedance signal measurement module (4), DSP signal processor unit (5) and wireless data transfer module (6); Described circuit board is provided with 8 or 16 union joints;
Described switching gate array (2) comprises the excitation gating switch for exciting electrode gating and the measurement gating switch for measurement electrode gating; Described excitation gating switch and described measurement gating switch are made up of 2 or 4 analog switching ic DG412 respectively, and the quantity measuring gating switch is equal with excitation gating switch quantity;
Described multi-frequency excitation current source (3) comprises DDS multi-frequency signal generator and Voltage to current transducer module, described DDS multi-frequency signal generator is made up of the DDS chip of ADI company, and described Voltage to current transducer module adopts chip current mirror option A D844 based on ADI company or differential amplifier current source side case AD8130;
Described impedance signal measurement module (4) comprises preposition instrument amplifier, programmable amplifier, AC-DC demodulator and AD conversion module; Described preposition instrument amplifier selects the instrument amplifier of ADI company; Described programmable amplifier selects the product of ADI company or TI company; ADI company root-mean-square value detection chip selected by described AD-DC demodulator; Described AD conversion module selects ADI company or 16, TI company or 24 AD conversion chip;
Described DSP unit (5) selects the DSP process chip of TI company;
Described wireless data transfer module (6) adopts the transmission system based on bluetooth more than 4.0 chip;
Electrode button on described elasticity elastic waist band is connected with the union joint on described circuit board by standard lead line, each union joint is also connected with the output of the way switch encouraged in gating switch with the input of the way switch measured in gating switch respectively, and the state being decided electrode by the control of switch is for excitation or measures;
DDS multi-frequency signal generator described in the IO port controlling of described DSP unit (5) produces the ac voltage signal for encouraging, this ac voltage signal is input to the signal input part of Voltage to current transducer module, through Voltage to current transducer, export the excitation current source of satisfying the demand, the excitation current source of generation is injected into the input of each way switch of excitation gating switch;
Detecting electrode to be transported to preposition instrument amplifier signal input part to upper voltage signal is picked up successively by measuring the gating of gating switch, the input of programmable amplifier is transported to through the signal of enlarge leadingly, by the IO port controlling programming amplifying multiple of DSP unit, signal is through programming amplifying, to export and the input being transported to AC-DC demodulator carries out AC-DC converts d. c. voltage signal at the outfan of programmable amplifier, this voltage signal is directly inputted to the input end of analog signal of AD conversion module, DSP unit controls AD conversion module is carried out data conversion and reads transformation result, the transformation result of AD conversion module is uploaded portable intelligent device by DSP unit controls wireless data transfer module simultaneously.
2. wearable electrical impedance tomography gastric motility information extraction element according to claim 1, is characterized in that, described DDS multiple-frequency signal generating unit adopts AD9832 chip or AD9850 chip.
3. wearable electrical impedance tomography gastric motility information extraction element according to claim 1, is characterized in that, described preposition instrument amplifier is a in AD8421 chip, AD8221 chip and AD8220 chip.
4. wearable electrical impedance tomography gastric motility information extraction element according to claim 1, is characterized in that, what what described programmable amplifier was selected was in THS7001, THS7002 and AD8251 is a.
5. wearable electrical impedance tomography gastric motility information extraction element according to claim 1, it is characterized in that, described DSP unit selects the TMS320C5509 chip of TI company.
6. wearable electrical impedance tomography gastric motility information extraction element according to claim 1, is characterized in that, described AD-DC demodulator selects ADI company root-mean-square value to detect AD637 chip.
7. wearable electrical impedance tomography gastric motility information extraction element according to claim 1, it is characterized in that, described AD conversion module selects ADS1274 or ADS1278 chip.
8. wearable electrical impedance tomography gastric motility information extraction element according to claim 1, it is characterized in that, described portable intelligent device is mobile phone, panel computer, intelligent watch or Intelligent bracelet.
9. a wearable electrical impedance tomography gastric motility information extracting method, is characterized in that, adopt wearable electrical impedance tomography gastric motility information extraction element as claimed in claim 1, concrete steps are as follows:
Step one, the elasticity elastic waist band (1) with electrod-array is placed in the body surface projection area of wearer's abdominal part stomach, by bonding strip, elasticity elastic waist band is connected to form endless belt, buckles at each electrode of elasticity elastic waist band and be provided with the disposable electrocardioelectrode of a standard respectively;
Step 2, described DSP signal processor unit control DDS multi-frequency signal generator generation amplitude is variable, the ac voltage signal of frequency-adjustable, and Voltage to current transducer module converts this ac voltage signal to excitation current source; Successively exciting current is injected in the pair of electrodes of elasticity elastic waist band by described excitation gating switch,
The impedance signal that on step 3, described measurement gating switch pickup elasticity elastic waist band, respective electrode is right;
Step 4, described preposition instrument amplifier once pick up amplification to the impedance signal on this electrode pair, programmable amplifier carries out secondary programming amplifying to the impedance signal once amplified, separate through AC-DC successively through the impedance signal of twice amplification and be in harmonious proportion AD conversion and become the digital signal of DSP signal processor unit identification, and this digital signal is passed on portable intelligent device through wireless data transfer module carry out date processing.
10. wearable electrical impedance tomography gastric motility information extracting method according to claim 9, is characterized in that,
In step 3, the quantity of described elasticity elastic waist band top electrode button is n, and wherein n is 8 or 16, adopts adjacent actuators measurement pattern, measures and obtains the individual impedance voltage value of n* (n-3).
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